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Artykuły w czasopismach na temat "MCE"

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Kumar, Ashwani, Mridula Bose i Vani Brahmachari. "Analysis of Expression Profile of Mammalian Cell Entry (mce) Operons of Mycobacterium tuberculosis". Infection and Immunity 71, nr 10 (październik 2003): 6083–87. http://dx.doi.org/10.1128/iai.71.10.6083-6087.2003.

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ABSTRACT The sequencing of the complete genome of M. tuberculosis H37Rv has resulted in the recognition of four mce operons in its genome by in silico analysis. In an attempt to understand the significance of the redundancy of mce operons, we analyzed the expression profile of mce operons after different periods of growth in culture as well as during in vivo infection. Our results strongly suggest that mce1 is expressed as a polycistronic message. In culture from day 8 to day 12, expression of only mce1 was observed, but as the cultures progress towards stationary phase the expression profile of mce operons was altered; the transcripts of the mce1 operon were barely detected while those of the mce4 operon were prominent. In an analysis of the expression of mce operons in tubercle material collected from infected animal tissues, we detected the expression of mce1, -3 and -4. Our results imply that mce operons other than mce1 are also expressed during infection and that it is necessary to examine their role in pathogenesis.
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El-Shazly, Sherief, Suhail Ahmad, Abu S. Mustafa, Raja Al-Attiyah i Dimitrolos Krajci. "Internalization by HeLa cells of latex beads coated with mammalian cell entry (Mce) proteins encoded by the mce3 operon of Mycobacterium tuberculosis". Journal of Medical Microbiology 56, nr 9 (1.09.2007): 1145–51. http://dx.doi.org/10.1099/jmm.0.47095-0.

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The mammalian cell entry (Mce) operon 3 (mce3) is one of four homologous mce operons of Mycobacterium tuberculosis, encoding six (Mce3A–F) invasin-like membrane-associated proteins. Previous studies have shown that recombinant expression of Mce1A encoded by the mce1 operon in Escherichia coli allows this non-pathogenic bacterium to invade and survive inside macrophages, and latex beads coated with Mce1A are internalized by non-phagocytic HeLa cells. However, the role of other mce1 operon proteins (Mce1B–F) and proteins encoded by the operons mce2–4 in facilitating the internalization of M. tuberculosis in mammalian cells has not been studied. This study was carried out to determine whether Mce proteins encoded by the mce3 operon also facilitated the internalization of latex beads by HeLa cells. Recombinant pure Mce3A and lipoprotein LprM (Mce3E) were expressed and purified from E. coli cells. Mce1A expressed as a fusion protein with glutathione S-transferase (GST–Mce1A) and GST alone, purified similarly from E. coli cells, were used as control proteins. Fluorescent latex beads coated with purified proteins were used to study their uptake by HeLa cells using fluorescence microscopy, flow cytometry and electron microscopy. Fluorescence microscopy and flow cytometry showed an association of HeLa cells with beads coated with both Mce3A and LprM, whilst GST–Mce1A and GST yielded the expected results. Transmission electron microscopy confirmed the uptake of beads coated with Mce3A or LprM by HeLa cells. The data showed that Mce3A encoded by the mce3 operon facilitated the uptake and internalization of latex beads by HeLa cells. The data also showed, for the first time, the role of another Mce protein (LprM/Mce3E) in facilitating the interaction and internalization of M. tuberculosis by mammalian cells.
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Asthana, Pooja, Dhirendra Singh, Jan Skov Pedersen, Mikko J. Hynönen, Ramita Sulu, Abhinandan V. Murthy, Mikko Laitaoja, Janne Jänis, Lee W. Riley i Rajaram Venkatesan. "Structural insights into the substrate-binding proteins Mce1A and Mce4A from Mycobacterium tuberculosis". IUCrJ 8, nr 5 (28.07.2021): 757–74. http://dx.doi.org/10.1107/s2052252521006199.

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Mycobacterium tuberculosis (Mtb), which is responsible for more than a million deaths annually, uses lipids as the source of carbon and energy for its survival in the latent phase of infection. Mtb cannot synthesize all of the lipid molecules required for its growth and pathogenicity. Therefore, it relies on transporters such as the mammalian cell entry (Mce) complexes to import lipids from the host across the cell wall. Despite their importance for the survival and pathogenicity of Mtb, information on the structural properties of these proteins is not yet available. Each of the four Mce complexes in Mtb (Mce1–4) comprises six substrate-binding proteins (SBPs; MceA–F), each of which contains four conserved domains (N-terminal transmembrane, MCE, helical and C-terminal unstructured tail domains). Here, the properties of the various domains of Mtb Mce1A and Mce4A, which are involved in the import of mycolic/fatty acids and cholesterol, respectively, are reported. In the crystal structure of the MCE domain of Mce4A (MtMce4A39–140) a domain-swapped conformation is observed, whereas solution studies, including small-angle X-ray scattering (SAXS), indicate that all Mce1A and Mce4A domains are predominantly monomeric. Further, structural comparisons show interesting differences from the bacterial homologs MlaD, PqiB and LetB, which form homohexamers when assembled as functional transporter complexes. These data, and the fact that there are six SBPs in each Mtb mce operon, suggest that the MceA–F SBPs from Mce1–4 may form heterohexamers. Also, interestingly, the purification and SAXS analysis showed that the helical domains interact with the detergent micelle, suggesting that when assembled the helical domains of MceA–F may form a hydrophobic pore for lipid transport, as observed in EcPqiB. Overall, these data highlight the unique structural properties of the Mtb Mce SBPs.
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Baba, Yuko, Atsushi Shimonaka, Jinichiro Koga, Hidetoshi Kubota i Toshiaki Kono. "Alternative Splicing Produces Two Endoglucanases with One or Two Carbohydrate-Binding Modules in Mucor circinelloides". Journal of Bacteriology 187, nr 9 (1.05.2005): 3045–51. http://dx.doi.org/10.1128/jb.187.9.3045-3051.2005.

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ABSTRACT We previously cloned three endoglucanase genes, rce1, rce2, and rce3, that were isolated from Rhizopus oryzae as the first cellulase genes from a member of the subdivision Zygomycota. In this study, two cDNAs homologous to the rce1 gene, designated the mce1 and mce2 cDNAs, were cloned from Mucor circinelloides, a member of the subdivision Zygomycota. The mce1 cDNA encoded an endoglucanase (family 45 glycoside hydrolase) having one carbohydrate-binding module (CBM), designated MCE1, and the mce2 cDNA encoded the same endoglucanase having two tandem repeated CBMs, designated MCE2. The two cDNAs contained the same sequences but with a 147-bp insertion. The corresponding genomic mce gene consisted of four exons. The mce1 cDNA was created from exons 1, 3, and 4, and the mce2 cDNA was created from exons 1, 2, 3, and 4. These results indicate that the mce1 and mce2 cDNAs were created from one genomic mce gene by alternative splicing. MCE1 and MCE2, purified to apparent homogeneity from the culture supernatant of M. circinelloides, had molecular masses of 43 and 47 kDa, respectively. The carboxymethyl cellulase specific activity of MCE2 was almost the same as that of MCE1, whereas the Avicelase specific activity of MCE2 was two times higher than that of MCE1. Furthermore, MCE2, whose two tandem CBMs might be more effective for degradation of crystalline cellulose than one CBM, was secreted only at an early culture stage when crystalline cellulose was abundant.
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Wongverawattanakul, Chonnipa, Phim on Suklaew, Charoonsri Chusak, Sirichai Adisakwattana i Thavaree Thilavech. "Encapsulation of Mesona chinensis Benth Extract in Alginate Beads Enhances the Stability and Antioxidant Activity of Polyphenols under Simulated Gastrointestinal Digestion". Foods 11, nr 15 (8.08.2022): 2378. http://dx.doi.org/10.3390/foods11152378.

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The aim of this study was to investigate the stability and antioxidant activity of the polyphenols from Mesona chinensis Benth extract (MCE) and its alginate-based encapsulation by extrusion technique during simulated gastrointestinal digestion. The encapsulation efficacy ranged from 41.1 ± 4.7 to 56.7 ± 3.4% with different concentrations of MCE (50–75% v/v), sodium alginate (1.2–1.8% w/v), and CaCl2 solution (3–5% w/v). The optimal condition for MCE-loaded alginate beads (MCB) was composed of 75% MCE, 1.5% alginate, and 3% CaCl2 solution, which provided the highest encapsulation efficiency with a spherical structure and a mean particle diameter of 1516.67 ± 40.96 μm. Fourier transform infrared spectroscopy (FT-IR) reported no chemical interaction between alginate and MCE. The release of total phenolic content (TPC) was only 8.9% after placing MCB in water for 4 h. After simulated digestion, changes in TPC and ferric reducing antioxidant power (FRAP) of MCE significantly decreased by 25.0% and 29.7%, respectively. Interestingly, the incorporation of MCB significantly increased TPC and FRAP in the digesta compared to those of MCE during gastrointestinal tract conditions. The findings suggest that the encapsulation of MCE with alginate as a carrier helps to improve the bioaccessibility and biological activity of M. chinensis polyphenols.
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Myagkonosov, D. S., I. T. Smykov, D. V. Abramov, I. N. Delitskaya i V. N. Krayushkina. "Effect of the recombinant chymosins of different origins on production process of soft cheese". Food systems 5, nr 2 (11.07.2022): 164–71. http://dx.doi.org/10.21323/2618-9771-2022-5-2-164-171.

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The effect of milk-clotting enzymes (MCE) with different milk-clotting activity (MCA) and proteolytic activity (PA) based on recombinant calf chymosins (Chy-max® Extra: MCA=554 IMCU/g; PA=0.71 UA/g), camel (Chymax® M: MCA=904 IMCU/g; PA=0.68 PA units/g) and “modified” chymosin (Chy-max® Supreme: MCA=912 IMCU/g; PA=0.26 PA units/g) on the duration of milk coagulation, the composition of whey and fresh cheeses in the production of soft cheese of the Italian type Crescenza at a dose of MCE equal to 1500, 2500 and 3500 IMCU per 100 kg of milk was studied. With an equal introduction dose, the shortest average duration of curd formation is noted for Chy-max Supreme MCE (15.0–27.5 min), long one — for Chy-max M MCE (17.0–31.0 min), and the longest one — for MCE Chy-max Extra (18.0–35.5 min). There was no statistically significant effect (p<0.05) of the type and dose of MCE on the total duration of cheese processing, as well as on the content of fat, protein and dry matter of whey. The type and dose of MCE had an impact on the properties of fresh cheeses: cheese options produced with the maximum dose of Chy-max Supreme had a statistically significant (p><0.05) higher average dry matter content (49.61%) than cheese options made with minimal doses of MCE (47.64–47.91%).>< 0.05) of the type and dose of MCE on the total duration of cheese processing, as well as on the content of fat, protein and dry matter of whey. The type and dose of MCE had an impact on the properties of fresh cheeses: cheese options produced with the maximum dose of Chy-max Supreme had a statistically significant (p<0.05) higher average dry matter content (49.61%) than cheese options made with minimal doses of MCE (47.64–47.91%).> <0.05) of the type and dose of MCE on the total duration of cheese processing, as well as on the content of fat, protein and dry matter of whey. The type and dose of MCE had an impact on the properties of fresh cheeses: cheese options produced with the maximum dose of Chy-max Supreme had a statistically significant (p<0.05) higher average dry matter content (49.61%) than cheese options made with minimal doses of MCE (47.64–47.91%).><0.05) higher average dry matter content (49.61%) than cheese options made with minimal doses of MCE (47.64–47.91%).
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Senaratne, Ryan H., Ben Sidders, Patricia Sequeira, Grainne Saunders, Kathleen Dunphy, Olivera Marjanovic, J. Rachel Reader i in. "Mycobacterium tuberculosis strains disrupted in mce3 and mce4 operons are attenuated in mice". Journal of Medical Microbiology 57, nr 2 (1.02.2008): 164–70. http://dx.doi.org/10.1099/jmm.0.47454-0.

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The Mycobacterium tuberculosis genome contains four copies of an operon called mce (mce1–4). Previously we reported that M. tuberculosis disrupted in the mce1 operon is more virulent than wild-type M. tuberculosis in mice. We generated single deletion mutants in mce3 (Δmce3) and mce4 (Δmce4) operons and a double deletion mutant (Δmce3/4). Similar doubling times and growth characteristics were observed for all mutants and the wild-type (parent) M. tuberculosis H37Rv strain in culture and in macrophages. In addition, similar bacterial burdens were detected in organs from mice infected with Δmce3 and the parent strain. However, the bacterial burdens of mice infected with Δmce4 and Δmce 3/4 were less than those of mice infected with the parent strain. The median survival times of mice infected with wild-type M. tuberculosis, Δmce3, Δmce4 and Δmce3/4 were 40.5, 46, 58 and 62 weeks, respectively. Histopathological examination of lungs at 15 weeks post-infection showed that the extent of the lung lesions was less prominent in mice infected with Δmce4 and Δmce 3/4 mutants than in mice infected with the other two strains. These observations suggest that the mce3 and mce4 operons have a role distinct from that of mce1 for in vivo survival of M. tuberculosis.
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Fongsamut, Kanokkarn, Monsit Tanasittikosol i Mingkhuan Phaksunchai. "Effectiveness of the simulation-based learning (SBL) assisted with scaffolding approach to address students’ misconceptions about projectile motion". Physics Education 58, nr 2 (14.12.2022): 025002. http://dx.doi.org/10.1088/1361-6552/aca57d.

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Abstract This research studied the effectiveness of the simulation-based learning assisted with scaffolding approach to address students’ misconceptions (MCs) about projectile motion. The five MCs were related to the direction of the force acting on an object (MC1), the acceleration of an object at the top of the trajectory (MC2), the directions of velocity and acceleration during projectile motion (MC3), the time of flight of objects (MC4), and the relationship between the range of projectile motion and angle of projection (MC5). This study was a pre-experimental design using both quantitative and qualitative data. The sample comprised 35 tenth-grade Thai high school students who were chosen using the cluster sampling technique. The teaching method consisted of three steps: a briefing, simulation, and debriefing. Each step was assisted with scaffolding to guide and help the students. The MCs tests consisted of five multiple-choice questions with a four-tier diagnostic test, and the tests were used as a pre-test, end-of-class test, and end-of-topic test. Six semi-structured interview questions were used to obtain in-depth data. The results indicated that MC1, MC2, MC3, MC4, and MC5 were addressed by 11.1%, 85.7%, 57.2%, 57.2%, and 61.5%, respectively, at the end-of-topic test. Students who had MCs in the pre-test changed their understanding of the concepts in MC2, MC3, MC4, and MC5 by 57.1%, 14.3%, 28.6%, and 53.8%, respectively. None of the MC students in MC1 understood the concept at the end-of-topic test. Nevertheless, the overall results showed increased students’ understanding of all conceptions.
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Wang, Jingxin, Mengxi Yang, Zhi Yang, Lu Ye, Hong Luo i Yingkun Guo. "Long-Term Prognostic Value of Myocardial Viability by Myocardial Contrast Echocardiography in Patients after Acute Myocardial Infarction: A Systematic Review and Meta-Analysis". Medicina 58, nr 10 (11.10.2022): 1429. http://dx.doi.org/10.3390/medicina58101429.

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Background and Objectives: According to recent guidelines, myocardial contrast echocardiography (MCE) is recommended for detecting residual myocardial viability (MV). However, the long-term prognostic value of MV as assessed by MCE in identifying major adverse cardiac events (MACE) after acute myocardial infarction (AMI) remains undefined. Materials and Methods: We searched multiple databases, including PubMed, EMBASE, and Web of Science for studies on the prognostic value of MCE for clinical outcomes in AMI patients. The primary endpoints were MACEs during follow-up. Six studies that evaluated a total of 536 patients with a mean follow-up of 36.8 months were reviewed. Results: The pooled sensitivity and specificity of MCE for predicting MACEs were 0.80 and 0.78, respectively, and the summary operating receiver characteristics achieved an area under the curve of 0.84. The pooled relative risks demonstrated that the MV evaluated by MCE after AMI was correlated with a high risk for total cardiac events (pooled relative risk: 2.07; 95% confidence interval: 1.28–3.37) and cardiac death (pooled relative risk: 2.48; 95% confidence interval: 1.03–5.96). MV evaluated by MCE was a highly independent predictor of total cardiac events (pooled hazard ratio: 2.09, 95% confidence interval: 1.14–3.81) in patients after AMI. Conclusions: Residual MV evaluated by MCE may be an effective long-term prognostic tool for predicting MACE in patients after AMI that can provide moderate predictive accuracy. The assessment of MV by MCE may become an alternative technique with the potential to rapidly provide important information for improving long-term risk stratification in patients after AMI, at the bedside in clinical practice, especially for patients who cannot tolerate prolonged examinations. The PROSPERO registration number is CRD42020167565.
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Myagkonosov, D. S., I. T. Smykov, D. V. Abramov, I. N. Delitskaya i V. N. Krayushkina. "Influence of different milk-clotting enzymes on the process of producing soft cheeses". Food systems 4, nr 3 (16.10.2021): 204–12. http://dx.doi.org/10.21323/2618-9771-2021-4-3-204-212.

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The effect of the type of milk clotting enzyme (MCE) on the duration of milk coagulation, parameters of the composition of whey and cheeses, and the output of cheeses in the production of soft cheese such as “Lyubitel'skiy” were investigated. Three brands of MCE of different origins were investigated: Marzyme® (MCE of microbial origin based on Rhizomucor miehei protease), Naturen® (calf rennet) and Chy-max® M (recombinant camel chymosin). It was established that MCEs had different ratios of milk clotting activity (MCA) to total proteolytic activity (PA). It was determined that the MCA/PA ratio, which characterizes the degree of specificity of the MCE action with regard to kappa-casein, in Chy-max M 1000 is ~7 times higher than that of Naturen and ~50 times higher than that of Marzyme. Such differences did not lead to a negative effect when using the Marzyme preparation in the production of soft cheeses. There were no statistically significant differences in the amount of dry matter loss of the curd into the whey, physicochemical parameters and output between the variants of cheeses made with the studied brands of MCE. Shorter duration of milk clotting (16.5 min) was observed with Marzyme than with MCE of Naturen (20.5 min) and Chy-max M (22.5 min). The results of the coagulation duration were explained by the stimulation of the activity of MCE of microbial origin, by the pH level of milk before coagulation (below pH 6.4). It was shown that modern MCEs of microbial origin could be recommended as a cost-effective replacement for more expensive rennet and recombinant chymosins in the production of soft and fresh cheeses.
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Rozprawy doktorskie na temat "MCE"

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Ma, Chuanhong. "MCE training basd continuous density HMM landmine detection system /". free to MU campus, to others for purchase, 2003. http://wwwlib.umi.com/cr/mo/fullcit?p1418048.

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Hilding, Fredrik, i Rebecca Ilehag. "Visualization and Analysis of Historical OHCA Occurrences and Other Risk Factors for Improved Placement of AEDs". Thesis, KTH, Geodesi och geoinformatik, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-147186.

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When an out of hospital cardiac arrest (OHCA) occurs, time is of the utmost importance. For every minute that the arrest goes untreated, the chance of survival decreases rapidly. The most common treatment, that is also the most known, is Cardiopulmonary Resuscitation (CPR). Thanks to new technology, the defibrillator is no longer a tool only available to hospital personnel but to anyone who knows where they are located. The objective of this thesis is partly to visualize OHCA occurrences as well as visualize the differences in OHCA occurrences between locations and years. The thesis will analyze where the optimal locations of AEDs are based on a number of variables such as location and year, which is referred to as risk analysis. The analysis was performed by using daytime and nighttime population data from Statistics Sweden (SCB) in combination with heart disease statistics from the national patient register of Socialstyrelsen as well as socio-economic data from SCB. Along with that data, AED locations at the end of 2013 and OHCA data from 2006 up until 2013 was used in visualizations and risk analysis. In order to determine the final optimal placement through the risk analysis, a Geographical Information System (GIS) tool named Multi-Criteria Evaluation (MCE) was used. This tool enabled the weighting of the different parameters against each other, which was integral for the final result. In order to visualize differences, e.g. between two years, a raster was created which consisted of a density difference between the two years. This analysis method shows the spots where there is a majority of either case, e.g. if one area had a larger number of OHCA cases one year compared to previous year. Simple plots were included to show an overview of the problem e.g. where OHCA occurred between the years 2006 and 2013. The results implied that the recommended locations of AEDs while using daytime population data were located in commercial areas. Recommended AEDs from using the nighttime population data was located differently but was located as well as clusters in residential areas. A large source of error in the analysis was the prior heart disease data. The chosen method, an assignment of a percentage chance of heart disease per age group, is a rough and inexact approximation of the actual heart disease statistics. Had there been data about exactly where patients with prior heart disease live and work, the results would most likely be even better.
När ett hjärtstopp utanför sjukhus (OHCA) inträffar, är tiden av yttersta vikt. För varje minut som hjärtstoppet går obehandlat minskar snabbt chansen för överlevnad. Den vanligaste behandlingen, som även är den mest kända, är hjärt- och lungräddning. Tack vare ny teknik är defibrillatorn inte längre ett verktyg som endast är tillgänglig för sjukvårdspersonal utan för alla som vet var de finns. Syftet med denna uppsats är att delvis visualisera förekomsten av OHCA men även att åskådliggöra skillnaderna mellan platser och år. I studien analyseras även, baserat på ett antal variabler, var de optimala platserna för Automatiska Externa Defibrillatorer (AED) är. Denna del av analysen är benämnd som riskanalys. Analysen genomfördes med hjälp av att använda dag- och nattidsbefolkningsdata från Statistiska Centralbyrån (SCB) i kombination med hjärtsjuksdomsstatistik från Socialstyrelsens nationella patientsregister och även socioekonomiska data från SCB. Dessa data, samt AED data från slutet av 2013 och OHCA data daterat från 2006 till 2013 användes både till visualiseringen och till riskanalysen. För att bestämma de slutgiltiga optimala platserna genom riskanalysen användes ett Geografiskt Information System (GIS) verktyg som heter multikriterieanalys (MCE). Detta verktyg gör det möjligt att vikta de olika parametrarna mot varandra, vilket var väsentligt för det slutgiltiga resultatet. För att kunna visualisera skillnader, till exempel mellan två år, skapades ett raster som bestod av en densitetskillnad mellan de två åren. Denna analysmetod kunde sedan visualisera var det finns en majoritet av det ena fallet, till exempel om ett område hade fler hjärtstopp ett år jämfört med tidigare år. Enklare kartor användes för att ge en översikt, till exempel var OHCA har skett mellan åren 2006 och 2013. Resultatet tyder på att de rekommenderade platserna för AED då dagtidsbefolkningsdata användes hamnade i områden med många arbetsplatser. De optimala platserna för AED med nattidsbefolkningsdata var annorlunda utplacerade men hamnade även dem i kluster i befolkningstäta områden med mycket bostäder. En av de större felkällorna i analysen tros vara hjärtsjuksdomsstatistiken. Den metod som användes var att extrahera ålder- och könsgrupper från ett patientregister vilket är en grov och inexakt approximation av den faktiska hjärtsjuksdomsstatistiken. Hade tillgång till data om var befolkning med hjärtsjukdomar faktiskt bor och arbetar funnits, kunde resultatet blivit mer pålitligt.
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Dávila, Flores Humberto Arturo. "Cambios en la representación social del conocimiento". Thesis, Universidad de las Américas Puebla, 2010. http://catarina.udlap.mx/u_dl_a/tales/documentos/mce/davila_f_ha/.

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Este trabajo explora el uso de la noción de "Representación Social" (Moscovici, S., 1961) en la evaluación de cambios en el conocimiento acerca de un objeto específico, con el cual se supone está familiarizada la población escolar de una área geográfica. Con tal fin se combinan las técnicas de redes semánticas naturales (Figueroa, González y Solis, 1981) y el diferencial semántico (Osgood, Succi & Tannenbaum, 1967) en la construcción de un artefacto experimental. El instrumento consta de dos encuestas aplicadas en dos tiempos distintos, dentro del intervalo de un mismo periodo semestral, a una muestra aleatoria de escolares de la misma área urbana (Cuautlancingo, San Andrés Cholula y San Pedro Cholula, en el Estado de Puebla). La muestra contó con la participación de 366 escolares, tanto del sector público como del privado, de distintas instituciones de Educación Primaria, Secundaria, Bachillerato y Licenciatura. Los resultados del análisis estadístico se han interpretado desde la perspectiva de la teoría del núcleo central (Abric, J-C, 1994), asumiendo que hay una génesis en la "representación social" (Duveen & Lloyd, 1990), una estructura (Chi, M., 2006) y una "práctica deliberada" (Ericsson y colaboradores, 1997) en la adquisición, modificación y conservación de la misma. Las transformaciones e invariancias observadas se evalúan en los términos de un modelo simple del desarrollo de conocimiento experto (Dreyfus y Dreyfus, 1980). Finalmente, se ensaya con dos formas de representar gráficamente la correspondencia entre el nivel de escolaridad y el conocimiento de los estudiantes acerca del objeto específico "Tecnologías de Información y Comunicación".
(cont.) La primera está basada en la homología de un sistema de masas que giran en torno de un centro de gravedad, o la situación del centroide de un constructo sobre el vértice de una sección cónica en el espacio unitario multivariable (Little y colaboradores, 1999). La otra, incorporando sobre una red tridimensional de vínculos y nodos los parámetros que el artefacto propuesto permite definir. Esta última tiene la ventaja de que puede construirse con gran facilidad mediante el "software" disponible para los mapas conceptuales ( http://cmap.ihmc.us/ ). Investigaciones de campo recientes han aplicado instrumentos con una metodología parecida, enfocando en otras regiones de nuestro país precisamente el mismo objeto de conocimiento (cf. Zermeño, Arellano y Ramírez, 2005). Así que la identificación de patrones mesurables en el dominio del conocimiento previo puede extraer elementos de juicio útiles, aprovechando el contraste que el presente estudio procura. San Andrés Cholula, Pue., mayo de 2010 .
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Bonilla, Mendoza Ana Lilia María. "La Educación Popular y sus posibilidades en la Educación Formal". Thesis, Universidad de las Américas Puebla, 2010. http://catarina.udlap.mx/u_dl_a/tales/documentos/mce/bonilla_m_al/.

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P��rez, De Le��n Marina. "Sistematizaci��n de la estrategia de formaci��n de j��venes voluntarios desarrollada por un educador social. El caso de una Organizaci��n Civil, el Centro de Comunicaci��n Popular". Thesis, Universidad de las Am��ricas Puebla, 2010. http://catarina.udlap.mx/u_dl_a/tales/documentos/mce/perez_d_m/.

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S��nchez, Sol��s Mariana. "TIC y transformaci��n docente: cambios en el conocimiento, las creencias pedag��gicas y la auto-percepci��n. Estudio de Casos en telesecundarias rurales". Thesis, Universidad de las Am��ricas Puebla, 2011. http://catarina.udlap.mx/u_dl_a/tales/documentos/mce/sanchez_s_m/.

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El presente estudio tiene como foco de inter��s el uso de las tecnolog��as de la informaci��n y la comunicaci��n como detonadores de la transformaci��n del conocimiento, las creencias pedag��gicas y la auto-percepci��n de los maestros. Esta investigaci��n fue realizada en escuelas telesecundarias rurales de la mixteca y la sierra norte del estado de Puebla. La metodolog��a responde al estudio de casos de una muestra de ocho docentes. Los resultados de la investigaci��n permiten establecer la transformaci��n que sufren los docentes en cuanto a su conocimiento tecnol��gico, sus creencias pedag��gicas y forma en que se auto perciben, as�� como las implicaciones que esta transformaci��n trae consigo.
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Gonz��lez, List Ver��nica. "Aprendizajes no intencionados en las organizaciones y movimientos civiles en M��xico entre 2002-2012 ��Qu�� nos dicen la investigaci��n y los conocedores expertos?" Thesis, Universidad de las Am��ricas Puebla, 2012. http://catarina.udlap.mx/u_dl_a/tales/documentos/mce/gonzalez_l_v/.

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Este trabajo es un estudio exploratorio-descriptivo que recoge y documenta lo concerniente con respecto al v��nculo entre aprendizajes no intencionados y procesos aglutinantes de la sociedad civil. Forma parte de un estudio m��s amplio sobre los estados del conocimiento en M��xico en la ��ltima d��cada (2002-2012) elaborados por el Consejo Mexicano de Investigaci��n Educativa (COMIE). Poco sabemos con respecto a lo que se aprende, sin que se tuviera la intenci��n, por participar en procesos civiles organizados que generalmente surgen por situaciones de exclusi��n, pobreza, violencia o injusticia. Aportar a la comprensi��n de la dimensi��n educativa de lo que ocurre dentro de los movimientos y las organizaciones sociales, es el objeto de este estudio. .
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Castillo, Sanguino Narciso. "Las TIC como herramienta docente para fortalecer la identidad cultural: estudio de casos en telesecundarias rurales de Puebla". Thesis, Universidad de las Am��ricas Puebla, 2011. http://catarina.udlap.mx/u_dl_a/tales/documentos/mce/castillo_s_n/.

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El equipamiento con TIC a las escuelas rurales corre de manera vertiginosa. Las TIC en las escuelas est��n generando otro tipo de din��micas. La incorporaci��n de las TIC enfrenta el reto de dotarlas de sentido tanto a nivel individual como colectivo. Este estudio de corte cualitativo se inserta dentro de este contexto. La pregunta de la que naci�� fue: ��pueden las TIC ser aplicadas para fortalecer la identidad culturalα Se utiliz�� la metodolog��a de estudio de casos seleccionando 4 casos (profesores que trabajan en zonas rurales) en el estado de Puebla. El modo de aproximaci��n al fen��meno de estudio fue a trav��s de entrevistas y documentos y teniendo como referente te��rico conceptual la Teor��a del Control Cultural de Bonfil. En base a la pregunta focal, se encontr�� que las TIC pueden encausar el fortalecimiento de la identidad cultural siempre y cuando los profesores sometan a las TIC a un proceso de apropiaci��n en t��rminos del control cultural.
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Sun, Yu. "Simulating Future Land Use Change in the East Fork Little Miami River (EFLMR) Watershed in Ohio". University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1236277626.

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Fu, Qiang. "A generalization of the minimum classification error (MCE) training method for speech recognition and detection". Diss., Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/22705.

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The model training algorithm is a critical component in the statistical pattern recognition approaches which are based on the Bayes decision theory. Conventional applications of the Bayes decision theory usually assume uniform error cost and result in a ubiquitous use of the maximum a posteriori (MAP) decision policy and the paradigm of distribution estimation as practice in the design of a statistical pattern recognition system. The minimum classification error (MCE) training method is proposed to overcome some substantial limitations for the conventional distribution estimation methods. In this thesis, three aspects of the MCE method are generalized. First, an optimal classifier/recognizer design framework is constructed, aiming at minimizing non-uniform error cost.A generalized training criterion named weighted MCE is proposed for pattern and speech recognition tasks with non-uniform error cost. Second, the MCE method for speech recognition tasks requires appropriate management of multiple recognition hypotheses for each data segment. A modified version of the MCE method with a new approach to selecting and organizing recognition hypotheses is proposed for continuous phoneme recognition. Third, the minimum verification error (MVE) method for detection-based automatic speech recognition (ASR) is studied. The MVE method can be viewed as a special version of the MCE method which aims at minimizing detection/verification errors. We present many experiments on pattern recognition and speech recognition tasks to justify the effectiveness of our generalizations.
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Książki na temat "MCE"

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MCE for Texas real estate professionals. Chicago, IL: Real Estate Education Co., 1999.

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1918-, Wiedemer John P., red. Keeping current with Texas real estate MCE. Wyd. 3. Mason, Ohio: Thomson/South-Western, 2004.

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1918-, Wiedemer John P., i Goeters Joseph E. 1934-, red. Keeping current with Texas real estate MCE. Mason, Ohio: Centage Learning, 2008.

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Jacobus, Charles J. Keeping current with Texas real estate MCE. Mason, Ohio: Thomson/South-Western, 2006.

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Jacobus, Charles J. Keeping current with Texas real estate MCE. Wyd. 2. Mason, Ohio: Thomson/South-Western, 2003.

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Jacobus, Charles J. Keeping current with Texas real estate MCE, 2004. Wyd. 4. Mason, Ohio: Thomson/South-Western, 2005.

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Vickery, V. R. Names for taxa proposed by the late D. Keith McE. Kevan (and taxa named to honour Kevan). Ste-Anne-de-Bellevue, Quebec, Canada: Lyman Entomological Museum and Research Laboratory, 1996.

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Tennefoss, Gregg. Preparing for Microsoft Windows 2000 professional MCP/MCSE certification. New York, NY: DDC Pub., 2001.

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Brock-Soldavini, Jada. ExamWise for MCP / MCSE certification: Microsoft Windows 2000 network infrastructure exam 70-216. Friendswood, Tex: TotalRecall Publications, 2003.

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Shapiro, Jeffrey R. ExamWise for MCP/MCSE certification: Microsoft Windows 2000 directory services infrastructure exam 70-219. Friendswood, Tex: TotalRecall Publications, 2003.

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Części książek na temat "MCE"

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Paegelow, M. "Multi Criteria Evaluation (MCE)". W Geomatic Approaches for Modeling Land Change Scenarios, 447–49. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-60801-3_26.

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Bensard, Denis D., Philip F. Stahel, Jorge Cerdá, Babak Sarani, Sajid Shahul, Daniel Talmor, Peter M. Hammer i in. "Mass-Casualty Event (MCE)". W Encyclopedia of Intensive Care Medicine, 1359. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-00418-6_1871.

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Hutchins, Tiffany, Giacomo Vivanti, Natasa Mateljevic, Roger J. Jou, Frederick Shic, Lauren Cornew, Timothy P. L. Roberts i in. "Manually Coded English (MCE)". W Encyclopedia of Autism Spectrum Disorders, 1804. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1698-3_100847.

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Khoury, A., Michael Halberthal, Gila Hymes, Liora Utitz, Shimon M. Reisner, Rami Mosheiff i Meir Liebergal. "Civilian Hospital Role in Mass Casualty Event (MCE)". W Orthopedics in Disasters, 61–81. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-48950-5_7.

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Alusaifeer, Tariq, Sheela Ramanna, Christopher J. Henry i James Peters. "GPU Implementation of MCE Approach to Finding Near Neighbourhoods". W Rough Sets and Knowledge Technology, 251–62. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-41299-8_24.

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Estoque, Ronald C., i Yuji Murayama. "Suitability Analysis for Beekeeping Sites Integrating GIS & MCE Techniques". W Spatial Analysis and Modeling in Geographical Transformation Process, 215–33. Dordrecht: Springer Netherlands, 2011. http://dx.doi.org/10.1007/978-94-007-0671-2_13.

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de Kare-Silver, Michael. "How Ready is your Organization to Become an Effective MCE?" W E-Shock 2020, 29–31. London: Palgrave Macmillan UK, 2011. http://dx.doi.org/10.1057/9780230343368_6.

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Pang, Zaihu, Xihong Wu i Lei Xu. "A Comparative Study of RPCL and MCE Based Discriminative Training Methods for LVCSR". W Intelligent Science and Intelligent Data Engineering, 27–34. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-31919-8_4.

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Li, Sinan, Zhuhuang Zhou i Shuicai Wu. "Nakagami Parametric Imaging Based on the Multi-pyramid Coarse-to-Fine Bowman Iteration (MCB) Method". W Proceeding of 2021 International Conference on Wireless Communications, Networking and Applications, 944–54. Singapore: Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-2456-9_96.

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AbstractNakagami-m parametric imaging has been used for imaging and detection of coagulation zone in microwave ablation. In order to improve the image smoothness and accuracy of coagulation zone detection, the multi-pyramid coarse-to-fine bowman iteration (MCB) method was proposed and compared with traditional moment-based estimator (MBE) method. Phantom simulations showed that the MCB method could obtain better image smoothness and higher accuracy in lateral target size detection than the MBE method. Experimental results of porcine liver ex vivo (n = 18) indicated that the m parameter obtained by the MCB method was more accurate than that obtained by the MBE method in detecting the coagulation zone. Nakagami-m parametric imaging based on MCB method can be used as a potential tool for microwave ablation monitoring.
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da Silva, José Alberto Fracassi, Claudimir Lucio do Lago, Dosil Pereira de Jesus i Wendell Karlos Tomazelli Coltro. "Capacitively Coupled Contactless Conductivity Detection (C4D) Applied to Capillary Electrophoresis (CE) and Microchip Electrophoresis (MCE)". W Capillary Electrophoresis and Microchip Capillary Electrophoresis, 145–60. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118530009.ch8.

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Streszczenia konferencji na temat "MCE"

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Roorda, Jonathan E., i Jeremy M. Wolfe. "The McCollough effect is a by-product of an internal error-correcting mechanism". W OSA Annual Meeting. Washington, D.C.: Optica Publishing Group, 1990. http://dx.doi.org/10.1364/oam.1990.wr6.

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The visual system requires error-correcting mechanisms that can cope with internal changes (e.g., cell death, lens yellowing). An error correcting mechanism might examine the statistical properties of the visual input and recalibrate if the input is inconsistent with normal visual stimulation.1 For example, on average, color and orientation are uncorrelated in natural stimuli. A correlation might indicate a change internal to the visual system (e.g., damage to one input to an orientationally-tuned, color opponent mechanism). In a standard McCollough effect (McE) paradigm, Ss adapt to red vertical and green horizontal stimuli, making white verticals appear greenish and white horizontals appear reddish. Adaptation to red vertical alone also produces a McE; however, adaptation to red vertical and red horizontal produces little or no McE. In all three cases, orientationally-selective color mechanisms are strongly stimulated and one might expect similar effects of adaptation. However, in the last there is no correlation between color and orientation and no stimulus for error-correction. These restrictions on the McE act to prevent erroneous recalibration under normal viewing conditions.2
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Wipf, David, Kensuke Sekihara i Srikantan Nagarajan. "EM Algorithms for Generalizing MCE and Focuss". W 2007 Joint Meeting of the 6th International Symposium on Noninvasive Functional Source Imaging of the Brain and Heart and the International Conference on Functional Biomedical Imaging. IEEE, 2007. http://dx.doi.org/10.1109/nfsi-icfbi.2007.4387678.

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Gonzalez, Javier, Javier G. Monroy, Francisco Garcia i Jose Luis Blanco. "The multi-chamber electronic nose (MCE-nose)". W 2011 IEEE International Conference on Mechatronics (ICM). IEEE, 2011. http://dx.doi.org/10.1109/icmech.2011.5971193.

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McDermott, Erik, i Shigeru Katagiri. "String-level MCE for continuous phoneme recognition". W 5th European Conference on Speech Communication and Technology (Eurospeech 1997). ISCA: ISCA, 1997. http://dx.doi.org/10.21437/eurospeech.1997-58.

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Zhou, Jianlai, Eric Chang i Chao Huang. "Selective MCE training strategy in Mandarin speech recognition". W 7th European Conference on Speech Communication and Technology (Eurospeech 2001). ISCA: ISCA, 2001. http://dx.doi.org/10.21437/eurospeech.2001-460.

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Jaehoon Kim, Heesook Mo, Wanchan Jung i Hojin Lee. "CCSDS packet data processing of KOMPSAT MCE system". W Proceedings of APCC/OECC'99 - 5th Asia Pacific Conference on Communications/4th Optoelectronics and Communications Conference. IEEE, 1999. http://dx.doi.org/10.1109/apcc.1999.825019.

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Bandara, K. R. Damindra S., Satish Kolli i Duminda Wijesekara. "Secure Intelligent Radio for Trains (SIRT)". W 2017 Joint Rail Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/jrc2017-2243.

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American Railroads are planning to complete implementing their Positive Train Control (PTC) systems by 2020. Safety objectives of PTC are to avoid inter-train collisions, train derailments and ensuring railroad worker safety. Under published specifications of I-ETMS (the PTC system developed by Class I freight railroads), the on-board PTC controller communicates with two networks; namely, the Signaling network and the Wayside Interface Unit network to gather navigational information such as the positions of other trains, the status of critical infrastructure (such as switches) and any hazardous conditions that may affect the train path. By design, PTC systems are predicated on having a reliable radio network operating in reserved radio spectrum, although the PTC system itself is designed to be a real-time fail safe distributed control systems. Secure Intelligent Radio for Trains (SIRT) is an intelligent radio that is customized to train operations with the aim of improving the reliability and security of the radio communication network. SIRT has two tiers. The upper tier has the Master Cognitive Engine (MCE) which communicates with other SIRT nodes to obtain signaling and wayside device information. To do so, the MCE communicates with cognitive engines at the lower tier of SIRT; namely the Cryptographic Cognitive Engine (CCE) (that provide cryptographic security and threat detection) and the Spectrum Management Cognitive Engine (SCE) (that uses spectrum monitoring, frequency hopping and adaptive modulation to ensure the reliability of the radio communication medium). We presented the architecture and the prototype development of the CCE in [1]. This paper presents the design of the MCE and the SCE. We are currently developing a prototype of the SCE and the MCE and testing the performance of our cognitive radio system under varying radio noise conditions. Our experiments show that SIRT dynamically switches modulation schemes in response to radio noise and switches channels in response to channel jamming.
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Wu, Gin-Der, i Zhen-Wei Zhu. "Matrix-MCE based fuzzy neural network for speech recognition". W 2014 11th IEEE International Conference on Control & Automation (ICCA). IEEE, 2014. http://dx.doi.org/10.1109/icca.2014.6870978.

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Peinado, Antonio M., Antonio J. Rubio, José C. Segura, Victoria Sanchez i Jesus E. Diaz. "MCE estimation of VQ parameters for MVQHMM speech recognition". W 4th European Conference on Speech Communication and Technology (Eurospeech 1995). ISCA: ISCA, 1995. http://dx.doi.org/10.21437/eurospeech.1995-28.

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Shimodaira, Hiroshi, Jun Rokui i Mitsuru Nakai. "Improving the generalization performance of the MCE/GPD learning". W 5th International Conference on Spoken Language Processing (ICSLP 1998). ISCA: ISCA, 1998. http://dx.doi.org/10.21437/icslp.1998-416.

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Raporty organizacyjne na temat "MCE"

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Peters, T., A. Washington, F. Fondeur i S. Fink. SOLVENT HOLD TANK SAMPLE RESULTS FOR MCU-11-314, MCU-11-315, MCU-11-316, MCU-11-317, MCU-11-318 AND MCU-11-319. Office of Scientific and Technical Information (OSTI), czerwiec 2011. http://dx.doi.org/10.2172/1018484.

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Peters, T., F. Fondeur i S. Fink. SOLVENT HOLD TANK SAMPLE RESULTS FOR MCU-11-1452, MCU-11-1453, MCU-11-1454, MCU-11-1455, MCU-11-1456 AND MCU-11-1457. Office of Scientific and Technical Information (OSTI), styczeń 2012. http://dx.doi.org/10.2172/1032954.

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Peters, T., A. Washington, F. . Fondeur i S. Fink. SUPPLEMENTAL ANALYSES FOR SOLVENT HOLD TANK SAMPLES MCU-11-314, MCU-11-315, MCU-11-316, MCU-11-317, MCU-11-318 AND MCU-11-319. Office of Scientific and Technical Information (OSTI), wrzesień 2011. http://dx.doi.org/10.2172/1026684.

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Fondeur, F. F., i K. M. Taylor-Pashow. Solvent Hold Tank Sample Results For MCU-13-814, MCU-13-815, MCU-13-816, MCU-13,817, MCU-13-818 And MCU-13-819: Quarterly Sample From May 2013. Office of Scientific and Technical Information (OSTI), sierpień 2013. http://dx.doi.org/10.2172/1090763.

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Fondeur, F. F., T. B. Peters i S. D. Fink. SOLVENT HOLD TANK SAMPLE RESULTS FOR MCU-12-488, MCU-12-489, MCU-12-490, MCU-12-491, MCU-12-492 AND MCU-12-493: QUARTERLY SAMPLE FROM OCTOBER 2012. Office of Scientific and Technical Information (OSTI), styczeń 2013. http://dx.doi.org/10.2172/1061033.

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Fondeur, F. F., i T. B. Peters. Solvent hold tank sample results for MCU-13-143, MCU-13-144, MCU-13-145, MCU-13-146, MCU-13-147 AND MCU-13-148: quarterly sample from January 2013. Office of Scientific and Technical Information (OSTI), marzec 2013. http://dx.doi.org/10.2172/1073613.

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Chen, Mercy. Interaction of Dietary Genistein, Equol, and Aromatase Inhibitors on Growth of Estrogen-Dependent Human Breast Cancer (MCF-7Ca) Cell in Athymic Mice. Fort Belvoir, VA: Defense Technical Information Center, październik 2004. http://dx.doi.org/10.21236/ada431970.

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SEXTON, R. A. MCO Monitoring Plan. Office of Scientific and Technical Information (OSTI), wrzesień 2000. http://dx.doi.org/10.2172/804797.

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Howard, Marylesa, Aaron Luttman, Daniel Marks i Daniel Frayer. Mie Scattering Analysis. Office of Scientific and Technical Information (OSTI), grudzień 2016. http://dx.doi.org/10.2172/1755228.

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Deng, Yingjun, ShengJing Liu, Ming Zhao, Feng Zhao, Jun Guo i Bin Yan. Diet-induced male infertility in mice models: a systematic review and network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, maj 2022. http://dx.doi.org/10.37766/inplasy2022.5.0116.

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Review question / Objective: In order to compare the different high energy diet such as high-fat diet and high sugar diet how to damage the male mice model in metabolize and fertility,and explore a reliable mice model method in the study of obesity with male infertility. P:obesity mice model with male infertility. I: High energy diet such as High-fat or High-sugar diet. C:High-fat diet,High-sugar diet, compared with normal diet in mice model. O:High energy diet induce male mice obesity model and damage their fertility. S: Use network meta-analysis. Condition being studied: The relationship between obesity and male infertility attacth more and more attention at present.So many animal expriments are carried out on this problem,there are enough exprimental article to support this meta analysis.
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