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Artykuły w czasopismach na temat „Mammalian tissues”

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Data publikacji: 4 czerwca 2021

Data aktualizacji: 20 lutego 2023

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1

Graham, John. "Homogenization of Mammalian Tissues". Scientific World JOURNAL 2 (2002): 1626–29. http://dx.doi.org/10.1100/tsw.2002.849.

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Satisfactory homogenization of a tissue is a necessary prerequisite to any fractionation schedule. A detailed protocol is given for rat liver because of the widespread use of this tissue. Although this technique should be broadly applicable to any soft tissue and to any subsequent fractionation procedure, there are certain tissues and applications that require either minor or extensive modification. Some of these points are addressed in the Notes section.

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2

Khrameeva, Ekaterina, Ilia Kurochkin, Katarzyna Bozek, Patrick Giavalisco i Philipp Khaitovich. "Lipidome Evolution in Mammalian Tissues". Molecular Biology and Evolution 35, nr 8 (11.05.2018): 1947–57. http://dx.doi.org/10.1093/molbev/msy097.

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3

Antonsson, Bruno. "Phosphatidylinositol synthase from mammalian tissues". Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1348, nr 1-2 (wrzesień 1997): 179–86. http://dx.doi.org/10.1016/s0005-2760(97)00105-7.

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4

Fei, D. Y., i K. K. Shung. "Ultrasonic backscatter from mammalian tissues". Journal of the Acoustical Society of America 78, nr 3 (wrzesień 1985): 871–76. http://dx.doi.org/10.1121/1.393115.

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5

Kruse, Rikke, i Kurt Højlund. "Mitochondrial phosphoproteomics of mammalian tissues". Mitochondrion 33 (marzec 2017): 45–57. http://dx.doi.org/10.1016/j.mito.2016.08.004.

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6

COLEMAN, Catherine S., Guirong HU i Anthony E. PEGG. "Putrescine biosynthesis in mammalian tissues". Biochemical Journal 379, nr 3 (1.05.2004): 849–55. http://dx.doi.org/10.1042/bj20040035.

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l-Ornithine decarboxylase provides de novo putrescine biosynthesis in mammals. Alternative pathways to generate putrescine that involve ADC (l-arginine decarboxylase) occur in non-mammalian organisms. It has been suggested that an ADC-mediated pathway may generate putrescine via agmatine in mammalian tissues. Published evidence for a mammalian ADC is based on (i) assays using mitochondrial extracts showing production of 14CO2 from [1-14C]arginine and (ii) cloned cDNA sequences that have been claimed to represent ADC. We have reinvestigated this evidence and were unable to find any evidence supporting a mammalian ADC. Mitochondrial extracts prepared from freshly isolated rodent liver and kidney using a metrizamide/Percoll density gradient were assayed for ADC activity using l-[U-14C]-arginine in the presence or absence of arginine metabolic pathway inhibitors. Although 14CO2 was produced in substantial amounts, no labelled agmatine or putrescine was detected. [14C]Agmatine added to liver extracts was not degraded significantly indicating that any agmatine derived from a putative ADC activity was not lost due to further metabolism. Extensive searches of current genome databases using non-mammalian ADC sequences did not identify a viable candidate ADC gene. One of the putative mammalian ADC sequences appears to be derived from bacteria and the other lacks several residues that are essential for decarboxylase activity. These results indicate that 14CO2 release from [1-14C]arginine is not adequate evidence for a mammalian ADC. Although agmatine is a known constituent of mammalian cells, it can be transported from the diet. Therefore l-ornithine decarboxylase remains the only established route for de novo putrescine biosynthesis in mammals.

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7

Harry, Martin, i Daniel Comeskey. "Folate Measurement in Mammalian Tissues by Fluorescence Polarization". Pteridines 22, nr 1 (luty 2011): 105–10. http://dx.doi.org/10.1515/pteridines.2011.22.1.105.

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Abstract Measurement of folate in animal tissues is expensive and time-consuming. A fluorescence polarization assay has been developed that allows the rapid and inexpensive quantification of folate in various animal tissues. The concentration of tissue folate is determined by its ability to compete with the binding of Alexa-660-folate to bovine milk folate binding protein. The technique uses a few milligrams of material and is amenable to automated screening in 384-well microplates. Using this approach, the folate concentration in mouse liver, kidney & brain was found to be 21.4, 4.22 and 0.73 nanomoles/g fresh tissue, respectively. Packed human erythrocytes were found to contain 1.31 mM folate. These estimates are similar to published folate values for these tissues. Ascorbate was not included in the assay buffer because of its pro-oxidant effects in iron rich tissues such as erythrocytes and liver. The assay is homogeneous, completed within a few hours of the availability of the samples, and will enable the high throughput analyses of folate in human and animal samples.

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8

Okuda, Tetsuya. "Dietary Control of Ganglioside Expression in Mammalian Tissues". International Journal of Molecular Sciences 21, nr 1 (26.12.2019): 177. http://dx.doi.org/10.3390/ijms21010177.

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Gangliosides are series of glycosphingolipids containing sialic acids in the oligosaccharide portion in mammalian cells. Gangliosides are a component of cellular membranes and play roles in modulating membrane function and the activity of membrane proteins. Abnormal expression and metabolism of gangliosides lead to the onset of several conditions in humans, such as neurologic diseases, diabetes, and cancer. A number of studies have been carried out to date to investigate the role of gangliosides in these diseases, and the effect of diet on tissue expression of gangliosides has recently become a topic of interest in this field. As gangliosides are degraded in the intestinal tract, ingested food-derived gangliosides are not directly absorbed into tissues in vivo, but the degradation products can be absorbed and affect ganglioside expression in the tissues. Recent studies have also shown that the expression of gangliosides in tissue cells can be indirectly induced by controlling the expression of ganglioside metabolism-related genes via the diet. These results indicate that dietary control can regulate the expression levels of gangliosides in tissues, which is expected to play a role in preventing and treating ganglioside-related diseases. This review introduces recent studies on the effect of diet on the expression of gangliosides in tissues, with a focus on our findings.

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9

Hulbert, A. J., W. Mantaj i P. A. Janssens. "Development of mammalian endothermic metabolism: quantitative changes in tissue mitochondria". American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 261, nr 3 (1.09.1991): R561—R568. http://dx.doi.org/10.1152/ajpregu.1991.261.3.r561.

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The development of energy metabolism of mammalian tissues was assessed in the tammar wallaby Macropus eugenii by the measurement of mitochondrial parameters in the liver, heart, kidney, and brain. Tissues taken from wallabies (n = 27) ranging from 10-day-old pouch young (weighing approximately 4 g) to adults (averaging 6.2 kg) were weighed and fixed, and mitochondrial volume and mitochondrial membrane surface area (MMSA) were determined by quantitative electron microscopy techniques. Developmental changes in these parameters were analyzed chronologically and allometrically. Relative growth rates of all four tissues decreased during development. Liver and heart showed constant allometric growth throughout development, whereas kidney and brain showed biphasic allometric growth. Tissue metabolic intensity assessed by MMSA (m2/cm3 tissue) was constant in liver, showed a threefold increase in brain during pouch life, showed a fourfold increase in the heart between 100 and 200 days of age, and showed a twofold increase in the kidney at the end of pouch life. In all tissues, adult levels of tissue metabolic capacity were present at pouch exit. In all four tissues, total MMSAs were at "reptilian" levels at birth and gradually increased to "mammalian" levels. Each tissue exhibited a different developmental timetable. When the total MMSAs for all four tissues were summed there was a similar pattern of allometric development between summed MMSA and whole animal metabolic rate.

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10

Nagata, Takeaki, Shigetoshi Kage, Kojiro Kimura, Keiko Kudo i Midori Noda. "Sulfide Concentrations in Postmortem Mammalian Tissues". Journal of Forensic Sciences 35, nr 3 (1.05.1990): 12876J. http://dx.doi.org/10.1520/jfs12876j.

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11

Heacock, Anne M., i Bernard W. Agranoff. "CDP-diacylglycerol synthase from mammalian tissues". Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1348, nr 1-2 (wrzesień 1997): 166–72. http://dx.doi.org/10.1016/s0005-2760(97)00096-9.

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12

Ishidate, Kozo. "Choline/ethanolamine kinase from mammalian tissues". Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1348, nr 1-2 (wrzesień 1997): 70–78. http://dx.doi.org/10.1016/s0005-2760(97)00118-5.

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13

Wood, Jonathan. "Printing mammalian cells for replacement tissues". Materials Today 7, nr 6 (czerwiec 2004): 18. http://dx.doi.org/10.1016/s1369-7021(04)00278-0.

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14

Balsalobre, Aurélio. "Clock genes in mammalian peripheral tissues". Cell and Tissue Research 309, nr 1 (lipiec 2002): 193–99. http://dx.doi.org/10.1007/s00441-002-0585-0.

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15

Pett, J. Patrick, Matthew Kondoff, Grigory Bordyugov, Achim Kramer i Hanspeter Herzel. "Co-existing feedback loops generate tissue-specific circadian rhythms". Life Science Alliance 1, nr 3 (czerwiec 2018): e201800078. http://dx.doi.org/10.26508/lsa.201800078.

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Gene regulatory feedback loops generate autonomous circadian rhythms in mammalian tissues. The well-studied core clock network contains many negative and positive regulations. Multiple feedback loops have been discussed as primary rhythm generators but the design principles of the core clock and differences between tissues are still under debate. Here we use global optimization techniques to fit mathematical models to circadian gene expression profiles for different mammalian tissues. It turns out that for every investigated tissue multiple model parameter sets reproduce the experimental data. We extract for all model versions the most essential feedback loops and find auto-inhibitions of period and cryptochrome genes,Bmal1–Rev-erb-αloops, and repressilator motifs as possible rhythm generators. Interestingly, the essential feedback loops differ between tissues, pointing to specific design principles within the hierarchy of mammalian tissue clocks. Self-inhibitions ofPerandCrygenes are characteristic for models of suprachiasmatic nucleus clocks, whereas in liver models many loops act in synergy and are connected by a repressilator motif. Tissue-specific use of a network of co-existing synergistic feedback loops could account for functional differences between organs.

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16

Morrison, Jamie I., Sara Lööf, Pingping He i András Simon. "Salamander limb regeneration involves the activation of a multipotent skeletal muscle satellite cell population". Journal of Cell Biology 172, nr 3 (30.01.2006): 433–40. http://dx.doi.org/10.1083/jcb.200509011.

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In contrast to mammals, salamanders can regenerate complex structures after injury, including entire limbs. A central question is whether the generation of progenitor cells during limb regeneration and mammalian tissue repair occur via separate or overlapping mechanisms. Limb regeneration depends on the formation of a blastema, from which the new appendage develops. Dedifferentiation of stump tissues, such as skeletal muscle, precedes blastema formation, but it was not known whether dedifferentiation involves stem cell activation. We describe a multipotent Pax7+ satellite cell population located within the skeletal muscle of the salamander limb. We demonstrate that skeletal muscle dedifferentiation involves satellite cell activation and that these cells can contribute to new limb tissues. Activation of salamander satellite cells occurs in an analogous manner to how the mammalian myofiber mobilizes stem cells during skeletal muscle tissue repair. Thus, limb regeneration and mammalian tissue repair share common cellular and molecular programs. Our findings also identify satellite cells as potential targets in promoting mammalian blastema formation.

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17

Johnson, D. Thor, Robert A. Harris, Stephanie French, Paul V. Blair, Jinsam You, Kerry G. Bemis, Mu Wang i Robert S. Balaban. "Tissue heterogeneity of the mammalian mitochondrial proteome". American Journal of Physiology-Cell Physiology 292, nr 2 (luty 2007): C689—C697. http://dx.doi.org/10.1152/ajpcell.00108.2006.

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The functionality of the mitochondrion is primarily determined by nuclear encoded proteins. The mitochondrial functional requirements of different tissues vary from a significant biosynthetic role (liver) to a primarily energy metabolism-oriented organelle (heart). The purpose of this study was to compare the mitochondrial proteome from four different tissues of the rat, brain, liver, heart, and kidney, to provide insight into the extent of mitochondrial heterogeneity and to further characterize the overall mitochondrial proteome. Mitochondria were isolated, solubilized, digested, and subjected to quantitative liquid chromatography-mass spectroscopy. Of the 16,950 distinct peptides detected, 8,045 proteins were identified. High-confidence identification threshold was reached by 1,162 peptides, which were further analyzed. Of these 1,162 proteins, 1,149 were significantly different in content ( P and q values < 0.05) between at least 2 tissues, whereas 13 were not significantly different between any tissues. Confirmation of the mitochondrial origin of proteins was determined from the literature or via NH2-terminal mitochondrial localization signals. With these criteria, 382 proteins in the significantly different groups were confirmed to be mitochondrial, and 493 could not be confirmed to be mitochondrial but were not definitively localized elsewhere in the cell. A total of 145 proteins were assigned to the rat mitochondrial proteome for the first time via their NH2-terminal mitochondrial localization signals. Among the proteins that were not significantly different between tissues, three were confirmed to be mitochondrial. Most notable of the significantly different proteins were histone family proteins and several structural proteins, including tubulin and intermediate filaments. The mitochondrial proteome from each tissue had very specific characteristics indicative of different functional emphasis. These data confirm the notion that mitochondria are tuned by the nucleus for specific functions in different tissues.

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18

Ake Lu, Viviana Perez, Zhe Fei, Ken Raj i Steve Horvath. "Universal DNA Methylation Age Across Mammalian Tissues". Innovation in Aging 5, Supplement_1 (1.12.2021): 410. http://dx.doi.org/10.1093/geroni/igab046.1588.

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Abstract Aging is often perceived as a degenerative process caused by random accrual of cellular damage over time. In spite of this, age can be accurately estimated by epigenetic clocks based on DNA methylation profiles from almost any tissue of the body. Since such pan-tissue epigenetic clocks have been successfully developed for several different species, it is difficult to ignore the likelihood that a defined and shared mechanism instead, underlies the aging process. To address this, we generated over 10,000 methylation arrays, each profiling up to 37,000 cytosines in highly-conserved stretches of DNA, from over 59 tissue-types derived from 128 mammalian species. From these, we identified and characterized specific cytosines, whose methylation levels change with age across mammalian species. Genes associated with these cytosines are greatly enriched in mammalian developmental processes and implicated in age-associated diseases. From the methylation profiles of these age-related cytosines, we successfully constructed three highly accurate universal mammalian clocks for eutherians, and one universal clock for marsupials. The universal clocks for eutherians are similarly accurate for estimating ages (r>0.96) of any mammalian species and tissue with a single mathematical formula. Collectively, these new observations support the notion that aging is indeed evolutionarily conserved and coupled to developmental processes across all mammalian species - a notion that was long-debated without the benefit of this new and compelling evidence.

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19

Bayraktar, Erol C., Lou Baudrier, Ceren Özerdem, Caroline A. Lewis, Sze Ham Chan, Tenzin Kunchok, Monther Abu-Remaileh i in. "MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo". Proceedings of the National Academy of Sciences 116, nr 1 (12.12.2018): 303–12. http://dx.doi.org/10.1073/pnas.1816656115.

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Mitochondria are metabolic organelles that are essential for mammalian life, but the dynamics of mitochondrial metabolism within mammalian tissues in vivo remains incompletely understood. While whole-tissue metabolite profiling has been useful for studying metabolism in vivo, such an approach lacks resolution at the cellular and subcellular level. In vivo methods for interrogating organellar metabolites in specific cell types within mammalian tissues have been limited. To address this, we built on prior work in which we exploited a mitochondrially localized 3XHA epitope tag (MITO-Tag) for the fast isolation of mitochondria from cultured cells to generate MITO-Tag Mice. Affording spatiotemporal control over MITO-Tag expression, these transgenic animals enable the rapid, cell-type-specific immunoisolation of mitochondria from tissues, which we verified using a combination of proteomic and metabolomic approaches. Using MITO-Tag Mice and targeted and untargeted metabolite profiling, we identified changes during fasted and refed conditions in a diverse array of mitochondrial metabolites in hepatocytes and found metabolites that behaved differently at the mitochondrial versus whole-tissue level. MITO-Tag Mice should have utility for studying mitochondrial physiology, and our strategy should be generally applicable for studying other mammalian organelles in specific cell types in vivo.

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20

Buckberry, Lorraine D., Ian S. Blagbrough, Barrie W. Bycroft i P. Nicholas Shaw. "Bovine Pulmonary, Hepatic and Renal Tissues: Models for the Study of Mammalian C-S Lyase Enzymes". Alternatives to Laboratory Animals 21, nr 3 (lipiec 1993): 360–70. http://dx.doi.org/10.1177/026119299302100306.

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C-S lyase (CSL) enzymes are responsible for the generation of toxicity via the cleavage of cysteine conjugates to generate reactive thiol species. In order to explore and characterise CSL activity in mammalian organs, cysteine conjugate CSL enzymes were isolated from bovine pulmonary, hepatic and renal tissues. Bovine tissue”, obtained from the abbatoir, affords a readily available source of viable CSL enzymes, without the necessity of sacrificing large numbers of laboratory animals simply to provide tissue. We have demonstrated that significant CSL activity exists in bovine tissues, and that the level of this activity is comparable with that found in human tissues. These enzymes provide an explanation for the previously reported episodes of bovine toxicity, and may provide a reasonable model for other mammalian CSL enzymes.

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21

SOHAR, ISTVAN, i GYORGY KATONA. "REGULATION OF PROTEINASE ACTIVATION IN MAMMALIAN TISSUES". Biological Chemistry Hoppe-Seyler 373, nr 2 (styczeń 1992): 567–72. http://dx.doi.org/10.1515/bchm3.1992.373.2.567.

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22

de la Rosa, Vanessa, José A. Campos-Sandoval, Mercedes Martín-Rufián, Carolina Cardona, José M. Matés, Juan A. Segura, Francisco J. Alonso i Javier Márquez. "A novel glutaminase isoform in mammalian tissues". Neurochemistry International 55, nr 1-3 (styczeń 2009): 76–84. http://dx.doi.org/10.1016/j.neuint.2009.02.021.

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23

Rees, S. A. "Electrical Properties of Mammalian Tissues: An Introduction." Cardiovascular Research 26, nr 10 (1.10.1992): 1008. http://dx.doi.org/10.1093/cvr/26.10.1008.

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24

Stefano, Anna Di, Maria Pizzichini, Germano Resconi i Enrico Marinello. "3 DETERMINATION OF ALLANTOIN IN MAMMALIAN TISSUES". Pediatric Research 24, nr 1 (lipiec 1988): 111. http://dx.doi.org/10.1203/00006450-198807000-00027.

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25

Kumble, Krishnanand D., i Arthur Kornberg. "Inorganic Polyphosphate in Mammalian Cells and Tissues". Journal of Biological Chemistry 270, nr 11 (17.03.1995): 5818–22. http://dx.doi.org/10.1074/jbc.270.11.5818.

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26

Chieffi Baccari, Gabriella, Sara Falvo, Alessandra Santillo, Federica Di Giacomo Russo i Maria Maddalena Di Fiore. "d-Amino acids in mammalian endocrine tissues". Amino Acids 52, nr 9 (wrzesień 2020): 1263–73. http://dx.doi.org/10.1007/s00726-020-02892-7.

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27

Plevin, Robin, i P. Jane Owen. "Multiple B2 kinin receptors m mammalian tissues". Trends in Pharmacological Sciences 9, nr 11 (listopad 1988): 387–89. http://dx.doi.org/10.1016/0165-6147(88)90059-4.

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28

Bahar Halpern, Keren, Inbal Caspi, Doron Lemze, Maayan Levy, Shanie Landen, Eran Elinav, Igor Ulitsky i Shalev Itzkovitz. "Nuclear Retention of mRNA in Mammalian Tissues". Cell Reports 13, nr 12 (grudzień 2015): 2653–62. http://dx.doi.org/10.1016/j.celrep.2015.11.036.

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29

Slivka, P. F., C. L. Dearth, T. J. Keane, F. W. Meng, C. J. Medberry, R. T. Riggio, J. E. Reing i S. F. Badylak. "Fractionation of an ECM hydrogel into structural and soluble components reveals distinctive roles in regulating macrophage behavior". Biomater. Sci. 2, nr 10 (2014): 1521–34. http://dx.doi.org/10.1039/c4bm00189c.

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Else, P. L., i A. J. Hulbert. "Evolution of mammalian endothermic metabolism: "leaky" membranes as a source of heat". American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 253, nr 1 (1.07.1987): R1—R7. http://dx.doi.org/10.1152/ajpregu.1987.253.1.r1.

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O2 consumption was measured at 37 degrees C in tissue slices of liver, kidney, and brain from Amphibolurus vitticeps and Rattus norvegicus (a reptile and mammal with same weight and body temperature) both in the presence and absence of ouabain. O2 consumption of the mammalian tissues was two to four times that of the reptilian tissues and the mammalian tissues used three to six times the energy for Na+-K+ transport than the reptilian tissues. Passive permeability to 42K+ was measured at 37 degrees C in liver and kidney slices, and passive permeability to 22Na+ was measured at 37 degrees C in isolated and cultured liver cells from each species. The mammalian cell membrane was severalfold "leakier" to both these ions than was the reptilian cell membrane, and thus the membrane pumps must use more energy to maintain the transmembrane ion gradients. It is postulated that this is a general difference between the cells of ectotherms and endotherms and thus partly explains the much higher levels of metabolism found in endothermic mammals.

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31

Keller, Chandler R., Kelsey F. Ruud, Steve R. Martinez i Weimin Li. "Identification of the Collagen Types Essential for Mammalian Breast Acinar Structures". Gels 8, nr 12 (18.12.2022): 837. http://dx.doi.org/10.3390/gels8120837.

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Modeling human breast tissue architecture is essential to study the pathophysiological conditions of the breast. We report that normal mammary epithelial cells grown in human breast extracellular matrix (ECM) hydrogel formed acini structurally similar to those of human and pig mammary tissues. Type I, II, III and V collagens were commonly identified in human, pig, and mouse breast ECM. Mammary epithelial cells formed acini on certain types or combinations of the four collagens at normal levels of breast tissue elasticity. Comparison of the collagen species in mouse normal breast and breast tumor ECM revealed common and distinct sets of collagens within the two types of tissues. Elevated expression of collagen type I alpha 1 chain (Col1a1) was found in mouse and human breast cancers. Collagen type XXV alpha 1 chain (Col25a1) was identified in mouse breast tumors but not in normal breast tissues. Our data provide strategies for modeling human breast pathophysiological structures and functions using native tissue-derived hydrogels and offer insight into the potential contributions of different collagen types in breast cancer development.

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32

Hulbert, A. J., i P. L. Else. "Evolution of mammalian endothermic metabolism: mitochondrial activity and cell composition". American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 256, nr 1 (1.01.1989): R63—R69. http://dx.doi.org/10.1152/ajpregu.1989.256.1.r63.

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Body composition was measured and compared in Amphibolurus vitticeps and Rattus norvegicus (a reptile and a mammal with the same weight and body temperature). Homogenates were prepared from liver, kidney, brain, heart, lung, and skeletal (gastrocnemius) muscle, and mitochondria were isolated. Cytochrome oxidase activities of both tissue homogenates and isolated mitochondria were measured (at 37 degrees C) as was protein content. Phospholipids were extracted from liver and kidney, and the fatty acid composition was determined. The brain, liver, kidney, heart, and skeletal muscle were significantly larger in the mammal, whereas the skin, reproductive organs, lung, and digestive tract showed no significant difference in size. All mammalian tissues examined contained approximately 50% more protein and phospholipid than the respective reptilian tissue. Although the mammalian phospholipids contained significantly less total unsaturated fatty acids, these unsaturated fatty acids were significantly more polyunsaturated than in the reptilian tissues. Tissue cytochrome oxidase activity was significantly greater in mammals when expressed on a wet weight basis but not when expressed on a tissue protein basis. Mitochondrial cytochrome oxidase activity (on a protein basis) was the same in both species in liver, kidney, and brain, but in heart, lung, and skeletal muscle mammalian mitochondria were twice as active as reptilian mitochondria. The implications of these differences in tissue composition were discussed relative to the evolution of mammalian endothermy.

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Zahra, Syeda Qandiel, Sidra Latif, Hira Nazir, Zunaira Izhar Shah, Azka Zafar, Ayesha Majid, Adil Farooq i Asif Mehmood Qureshi. "Efficacy of SDS For Protein Extraction from Broiler Muscles and Mammalian Liver Tissue". Albus Scientia 2022, nr 1 (24.06.2022): 1–4. http://dx.doi.org/10.56512/as.2022.1.e220624.

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Background: The present study purports to check and validate the potential of sodium dodecyl sulfate (SDS) alone being a suitable and cost-effective lysis buffer for maximum and efficient protein extraction from various muscle tissues of broiler chicken and mammalian liver. Materials and Methods: Three different muscle tissues (I; chest, II; wing and III; leg) were extracted from randomly selected commercial broilers (n=4) while mice (n=3) were dissected for the extraction of liver tissue samples. 1:1 ratio (w/v) of SDS; 10 and 1.0 & 1.5% was used for muscles and liver tissues, respectively for its best time optimization for protein extraction. After incubation, respective tissues were homogenized followed by centrifugation. The supernatant was then processed for crude protein (CP) extraction by Bromocresol Green (BCG) method. Results: SDS (10%) achieved a maximum yield of CP after 1 hour of incubation. When checked the co-dependence of SDS-reagent on muscle-tissue type and time of incubation, tissue I (chest) was found to give maximum CP contents after 1 hour of incubation, tissue II (wing) extracted more CP after 3 hours while tissue III (leg) rendered equal amounts of CP after 1, 2 and 3 hours of incubation, respectively. From the mammalian liver tissue maximum yield of CP (6.9 g/dl), and albumin (ALB) (1.6 g/dl) was obtained with 1.5% of SDS. While the CP and albumin (Alb) content was not detected after homogenization with 1.0% SDS. Significance was checked at (P< 0.05). Conclusion: It is concluded from the above findings that 10% SDS is the best lysis buffer concentration to extract crude protein from all the studied broiler muscle tissues while from mice liver samples we found 1.5% SDS lysis reagent seems good than 1.0%. Furthermore, this simple and cheapest procedure and ease of preparation this reagent may be suitable for extraction of important tissue protein fractions.

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Tsang, Christopher W., Mathew P. Estey, Jessica E. DiCiccio, Hong Xie, Dana Patterson i William S. Trimble. "Characterization of presynaptic septin complexes in mammalian hippocampal neurons". Biological Chemistry 392, nr 8-9 (1.08.2011): 739–49. http://dx.doi.org/10.1515/bc.2011.077.

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Abstract Septins are GTPases that form heteromeric complexes and are linked to neurological disorders. Although several septin subcomplexes have been reported in various mammalian tissues, the cellular and subcellular distribution of these complexes is largely unexplored. Using antibodies against ten mammalian septins, we show that septins diverge with respect to their tissue distribution implying that septin complexes in various tissues have unique composition. Although all ten septins examined were expressed in brain tissue, we describe septin complex(es) including SEPT3, SEPT5, SEPT6, SEPT7 and SEPT11 that could be functional within the presynapse because, unlike other septins they: (1) showed an increase in expression from embryonic day 15 to post-natal day 70, (2) were abundantly expressed in axons and growth cones of developing hippocampal neurons, (3) were found in presynaptic terminals of mature synapses, (4) were enriched in a preparation of synaptic vesicles and (5) immunoprecipitated together from brain tissue and cultured nerve cells. Knockdown of SEPT5 or SEPT7 in developing hippocampal neurons impaired axon growth. Because septins are functionally linked to the cytoskeleton and vesicle traffic, presynaptic neuronal septin complexes could be important for ensuring proper axon development and neurotransmitter release.

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TeSlaa, Tara, Caroline R. Bartman, Connor S. R. Jankowski, Zhaoyue Zhang, Xincheng Xu, Xi Xing, Lin Wang, Wenyun Lu, Sheng Hui i Joshua D. Rabinowitz. "The Source of Glycolytic Intermediates in Mammalian Tissues". Cell Metabolism 33, nr 2 (luty 2021): 367–78. http://dx.doi.org/10.1016/j.cmet.2020.12.020.

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Currey, John D., Kevin Brear i Peter Zioupos. "Notch sensitivity of mammalian mineralized tissues in impact". Proceedings of the Royal Society of London. Series B: Biological Sciences 271, nr 1538 (7.03.2004): 517–22. http://dx.doi.org/10.1098/rspb.2003.2634.

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Nagase, Hiroki, i Srimoyee Ghosh. "Epigenetics: differential DNA methylation in mammalian somatic tissues". FEBS Journal 275, nr 8 (7.03.2008): 1617–23. http://dx.doi.org/10.1111/j.1742-4658.2008.06330.x.

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Ganapathy, Vadivel, i Seiji Miyauchi. "Transport systems for opioid peptides in mammalian tissues". AAPS Journal 7, nr 4 (grudzień 2005): E852—E856. http://dx.doi.org/10.1208/aapsj070482.

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Jarry, Gilbert, Florence Henry i Robin Kaiser. "Anisotropy and multiple scattering in thick mammalian tissues". Journal of the Optical Society of America A 17, nr 1 (1.01.2000): 149. http://dx.doi.org/10.1364/josaa.17.000149.

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Seimetz, Joseph, Waqar Arif, Sushant Bangru, Mikel Hernaez i Auinash Kalsotra. "Cell-type specific polysome profiling from mammalian tissues". Methods 155 (luty 2019): 131–39. http://dx.doi.org/10.1016/j.ymeth.2018.11.015.

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Ueda, Natsuo, Kazuhito Tsuboi i Didier M. Lambert. "A second N-acylethanolamine hydrolase in mammalian tissues". Neuropharmacology 48, nr 8 (czerwiec 2005): 1079–85. http://dx.doi.org/10.1016/j.neuropharm.2004.12.017.

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Curatolo, W., F. B. Jungalwala, B. Sears, L. Tuck i L. J. Neuringer. "Deuterium NMR spectroscopy of biosynthetically deuterated mammalian tissues". Biochemistry 24, nr 16 (30.07.1985): 4360–64. http://dx.doi.org/10.1021/bi00337a017.

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Wagers, Amy J. "Systemic regulation of aging phenotypes in mammalian tissues". Experimental Gerontology 68 (sierpień 2015): 94. http://dx.doi.org/10.1016/j.exger.2015.01.012.

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Jitrapakdee, S., A. Vidal-Puig i J. C. Wallace. "Anaplerotic roles of pyruvate carboxylase in mammalian tissues". Cellular and Molecular Life Sciences 63, nr 7-8 (28.02.2006): 843–54. http://dx.doi.org/10.1007/s00018-005-5410-y.

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McClatchy, Daniel B., Lujian Liao, Sung Kyu Park, Tao Xu, Bingwen Lu i John R. Yates III. "Differential Proteomic Analysis of Mammalian Tissues Using SILAM". PLoS ONE 6, nr 1 (20.01.2011): e16039. http://dx.doi.org/10.1371/journal.pone.0016039.

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Emmett, Mark, i Barbara Petrack. "Rapid isolation of total RNA from mammalian tissues". Analytical Biochemistry 174, nr 2 (listopad 1988): 658–61. http://dx.doi.org/10.1016/0003-2697(88)90069-3.

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Pacher, P., J. Magyar, P. Szigligeti, T. Bányász, C. Pankucsi, Z. Korom, Z. Ungvári, V. Kecskeméti i P. P. Nánási. "Electrophysiological effects of fluoxetine in mammalian cardiac tissues". Naunyn-Schmiedeberg's Archives of Pharmacology 361, nr 1 (1.01.2000): 67–73. http://dx.doi.org/10.1007/s002109900154.

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Fonda, Margaret L. "Pyridoxamine (pyridoxine) phosphate oxidase activity in mammalian tissues". Comparative Biochemistry and Physiology Part B: Comparative Biochemistry 90, nr 4 (styczeń 1988): 731–37. http://dx.doi.org/10.1016/0305-0491(88)90327-6.

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Trounson, Alan. "Derivation characteristics and perspectives for mammalian pluripotential stem cells". Reproduction, Fertility and Development 17, nr 2 (2005): 135. http://dx.doi.org/10.1071/rd04119.

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Pluripotential stem cells have been derived in mice and primates from preimplantation embryos, postimplantation embryos and bone marrow stroma. Embryonic stem cells established from the inner cell mass of the mouse and human blastocyst can be maintained in an undifferentiated state for a long time by continuous passage on embryonic fibroblasts or in the presence of specific inhibitors of differentiation. Pluripotential stem cells can be induced to differentiate into all the tissues of the body and are able to colonise tissues of interest after transplantation. In mouse models of disease, there are numerous examples of improved tissue function and correction of pathological phenotype. Embryonic stem cells can be derived by nuclear transfer to establish genome-specific cell lines and, in mice, it has been shown that embryonic stem cells are more successfully reprogrammed for development by nuclear transfer than somatic cells. Pluripotential stem cells are a very valuable research resource for the analysis of differentiation pathways, functional genomics, tissue engineering and drug screening. Clinical applications may include both cell therapy and gene therapy for a wide range of tissue injury and degeneration. There is considerable interest in the development of pluripotential stem cell lines in many mammalian species for similar research interests and applications.

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Zhao, Jingjing, Hongbo Shi i Nadav Ahituv. "Classification of topological domains based on gene expression and regulation". Genome 56, nr 7 (lipiec 2013): 415–23. http://dx.doi.org/10.1139/gen-2013-0111.

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Tissue-specific gene expression is thought to be one of the major forces shaping mammalian gene order. A recent study that used whole-genome chromosome conformation assays has shown that the mammalian genome is divided into specific topological domains that are shared between different tissues and organisms. Here, we wanted to assess whether gene expression and regulation are involved in shaping these domains and can be used to classify them. We analyzed gene expression and regulation levels in these domains by using RNA-seq and enhancer-associated ChIP-seq datasets for 17 different mouse tissues. We found 162 domains that are active (high gene expression and regulation) in all 17 tissues. These domains are significantly shorter, contain less repeats, and have more housekeeping genes. In contrast, we found 29 domains that are inactive (low gene expression and regulation) in all analyzed tissues and are significantly longer, have more repeats, and gene deserts. Tissue-specific active domains showed some correlation with tissue-type and gene ontology. Domain temporal gene regulation and expression differences also displayed some gene ontology terms fitting their temporal function. Combined, our results provide a catalog of shared and tissue-specific topological domains and suggest that gene expression and regulation could have a role in shaping them.

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