Rozprawy doktorskie na temat „LNMB”
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Dumaz, Philippe. "Comportement électrochimique de matériaux à haut potentiel : LiCoPO4 et LiNi1/3Mn3/2O4, en électrodes couches minces ou composites". Thesis, Université Grenoble Alpes (ComUE), 2017. http://www.theses.fr/2017GREAI095/document.
Pełny tekst źródłaThe use of unlimited natural sources such as solar, wind or hydraulic power is booming. However, their energy production is dependant of climatic conditions and is therefore intermittent. These systems are usually associated with energy storage, in order to smooth the production before injection on the network. For all these reasons, Li-ion batteries need to incorporate new electrode materials to achieve high power and high energy density while maintaining a long life and safe use.In this context, our work consisted in preparing high potential materials, LiCoPO4 (LCP) and LiNi0.5Mn1.5O4 (LNMO). The latter are perfectly integered in the context of development of materials with high energy density since they have an oxidation potential of 4.8 and 4.7 V vs Li + / Li and theoretical mass energy densities of 802 and 691 Wh.kg-1 over lithium, respectively.These materials were first synthesized in the form of thin thin films to obtain model electrodes to study the kinetics and thermodynamics properties of materials transport and interactions with the presence of a liquid electrolyte including phenomena at the electrode interface / electrolyte. The understanding acquired during this first axis allowed us to transpose and adapt these characterization techniques to more complex systems : composite electrodes.The properties of these materials with respect to lithium insertion and desinsertion have been tested and characterized in electrochemicals cells. Kinetic and thermodynamic parameters have been extracted using several electrochemical techniques such as intermittent titration (GITT), impedance spectroscopy (PEIS and GEIS), galvano-static cycling and power tests. We propose a simple method, based on power tests, to determine the diffusion coefficient of lithium. Finally, we attempt to answer several questions that remain unsolved about the capacity loss of high potential materials during long cycling, and we propose a very simple technique for improving the cycling of composites electrodes of LNMO
Штанько, Д. Г. "Система живлення високочастотних BUC і LNB на основі застосування універсального інжектора". Master's thesis, Сумський державний університет, 2021. https://essuir.sumdu.edu.ua/handle/123456789/86600.
Pełny tekst źródłaSalian, Girish Dayanand. "Fabrication and characterization of thin-film microbatteries based on self-organized titania nanotubes". Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0396/document.
Pełny tekst źródłaSelf-supported titanium dioxide nanotube (TiO2 nts) is explored as a potential negative electrode for 3D Li-ion microbatteries. Different chemical modifications on the TiO2 nts have been explored and studied like Nb-alloyed TiO2 nts, ALD-Al2O3 coated TiO2 nts, Lithium titanate-TiO2 nts and sulphurized TiO2 nts. The deposition of PEO (polyethylene oxide) based polymer electrolyte (PMMA-PEG) carrying LiTFSI salt into TiO2 nts has been achieved by the electropolymerization reaction on the TiO2 nts anode and the Lithum nickel manganese oxide (LNMO) cathode. The main aim here was to exploit the active surface area of the electrodes using electrodeposition and there by enhance the electrode-electrolyte interface. Such a microbattery containing polymer-coated electrodes reveal that the capacity values obtained at different C-rates are doubled when the electrodes are completely filled by the polymer electrolyte compared with the microbattery with the raw electrodes. The excellent electrochemical performance is attributed to the improved electrode-electrolyte interfaces in both the electrodes
Stoll, Andreas Christian [Verfasser], i M. J. [Akademischer Betreuer] Hoffmann. "Ru-/Ti-substituierter LNMO-Spinell als positives Elektrodenmaterial für Li-Ionen-Batterien – Degradationsprozesse und ergänzende Strukturaufklärung / Andreas Christian Stoll ; Betreuer: M. J. Hoffmann". Karlsruhe : KIT-Bibliothek, 2020. http://d-nb.info/121003347X/34.
Pełny tekst źródłaMorales, Murillo Esteban. "Síntesis, Caracterización y Estudio de Resonancia Plasmónica de Superficie de Nanopartículas Core-Shell: Au-Pt y Ag-Au". Thesis, Universidad de las Américas Puebla, 2010. http://catarina.udlap.mx/u_dl_a/tales/documentos/lnm/morales_m_e/.
Pełny tekst źródłaC��rdenas, D��valos Lucero Arantxa. "Caracterizaci��n y estabilidad de los aceites esenciales de or��gano nanoencapsulados por nanoemulsiones para su acci��n antimicrobiana en carne cruda". Thesis, Universidad de las Am��ricas Puebla, 2012. http://catarina.udlap.mx/u_dl_a/tales/documentos/lnm/cardenas_d_la/.
Pełny tekst źródłaCarvajal, Rossainz Christian Gerardo. "Efecto de la incorporaci��n de Eu+3 en las propiedades optoelectr��nicas de nanopart��culas de TiO2". Thesis, Universidad de las Am��ricas Puebla, 2011. http://catarina.udlap.mx/u_dl_a/tales/documentos/lnm/carvajal_r_cg/.
Pełny tekst źródła(cont.) Las NPs obtenidas resultaron en una estructura amorfa y fueron tratadas t��rmicamente a determinadas temperaturas en aire para inducir la fase cristalina anatasa. Las nanoparticulas de TiO2 dopadas con Eu fueron sometidas a estudio de fotoluminiscencia (PL) con el objetivo de determinar los efectos del dopante sobre las propiedades optoelectr��nicas y evaluar sus posibles aplicaciones tecnol��gicas, su caracterizaci��n fue realizada mediante microscop��a SEM para la evaluaci��n del tama��o y morfolog��a de las NPs dopadas y no dopadas, se llev�� a cabo la caracterizaci��n por EDS para estudiar su composici��n de manera cualitativa y cuantitativa, la caracterizaci��n estructural por difracci��n de rayos X y espectroscopia Raman, y la evaluaci��n de sus propiedades optoelectr��nicas se realiz�� por medio de espectroscopia de fotoluminiscencia PL. Los resultados de todas las pruebas se discuten en el presente trabajo. Finalmente, este trabajo de investigaci��n consiste en la preparaci��n y caracterizaci��n de las nanoparticulas de TiO2 dopadas y no dopadas llevando a cabo procedimientos sencillos y econ��micos para promover sus usos m��s populares
López, Vázquez Ciro. "Preparación de Nanopartículas de ferritas magnéticas y su funcionalización superficial con polímeros (PEG y TREG) para su evaluación como agentes de contraste en imagenología de resonancia magnética nuclear (MRI)". Thesis, Universidad de las Américas Puebla, 2012. http://catarina.udlap.mx/u_dl_a/tales/documentos/lnm/lopez_v_c/.
Pełny tekst źródłaAlamilla, Peralta German. "Transistores de película delgada sobre substratos flexibles". Thesis, Universidad de las Américas Puebla, 2013. http://catarina.udlap.mx/u_dl_a/tales/documentos/lnm/alamilla_p_g/.
Pełny tekst źródłaCuahtecontzi, Delint Rosalía. "Estudio de Toxicidad de Nanopartículas de CeO2 en Diferentes Sistemas Biológicos". Thesis, Universidad de las Américas Puebla, 2013. http://catarina.udlap.mx/u_dl_a/tales/documentos/lnm/cuahtecontzi_d_r/.
Pełny tekst źródłaRoland, Lilian. "Etude du rôle de MYD88 et des voies NF-kB dans l'émergence des lymphomes B". Thesis, Limoges, 2021. http://www.theses.fr/2021LIMO0014.
Pełny tekst źródłaIt was estimated that 557 730 deaths from lymphoma worldwide in 2018 and are the 5th leading cause of cancer death in France. Basic and applied research in this area is therefore crucial to improve diagnostics and therapies. Cell signaling pathways of the transcription factor NF-κB, playing a central role in cell survival and proliferation, are frequently deregulated and involved in the emergence of non-Hodgkin B-cell lymphomas (B-NHL). The laboratory studies over these three years concerned the role of MYD88 and NF-κB in the context of the emergence of B cell-linked lymphomas. The L265P mutation of protein adaptor MYD88 (MYD88L265P), exacerbating toll-like receptor (TLR) signaling, receptors involved in the innate immune B cell response, results in constitutive NF-κB activation. This mutated protein MYD88L265P is found in many cases of LNH ranging from indolent lymphoplasmacytic lymphomas (LPL) to aggressive diffuse large B-cell lymphomas (DLBCL). Waldenström's macroglobulinemia (WM) presents in about 90% of cases this MYD88L265P mutation, making it a primary event in the emergence of this LPL. To study the consequences of this mutation on the transformation of the B cell, we carried out a in vivo study, thanks to a murine model expressing MYD88L252P (murine ortholog of the MYD88L265P mutation in humans) exclusively in B cells through the expression of CRE-recombinase due to the Cd19 promotor. Indeed, the study of this model developing a lymphoma close to WM, allowed us to visualize its transforming power on the B cell, but also the behavior of the cell in the microenvironment of an entire organism. We were able to confirm the ability of MYD88L252P to form a lymphoplasmacytic clone, as well as the presence of a serum monoclonal IgM peak and an IgM plasma cells invasion in the bone marrow, which are characteristics of WM.Immune escape is a major component in the emergence of B-LNH. In the case of lymphomas linked to the Epstein Barr virus (EBV), the B cells immortalized by this virus are also able to modulate the immune response. Regarding this last phenomenon, we have described the immunoregulatory profile in vitro of B cells infected by EBV in latency III. The LMP1 protein, produced during latency II and III, essentially activating the NF-κB alternative pathway, allows the overexpression of the immunomodulatory proteins PD-L1, IL-10, TGF-β1 and IL35 (EBI3 and IL12A). We have also demonstrated the expansion of conventional and unconventional regulatory T cells (Tregs) depending on the PD-1/PD-L1 axis. In many cancers, the PD-L1 surface protein is overexpressed, strongly impacting the microenvironment of tumor cells. Thus, in the case of DLBCL, this overexpression associated to poor prognosis. Due to its importance in the progression of the tumor, therapeutic tests with anti-PD-L1 antibodies can be very effective. For this, we did preclinical in vivo tests targeting PD-L1 directly, and ex vivo targeting the pathways allowing its expression. The L.CD40 (lmp1/cd40) murine model developing indolent lymphoma close to marginal zone lymphoma (MZL), in which we shown the overexpression of PD-L1 from tumoral B cells. We were able to demonstrate the beneficial effects of this treatment with a in vivo spleen size reduction and ex vivo PD-L1 downregulation, as well as T cell reactivation. These studies open new research perspectives on our MYD88 mouse model
Correard, Sebastien. "Calibration de l'etiquetage de jets issus de quarks beaux et recherche du boson de Higgs dans le canal ttH -> lnub jjb bb dans l'experience ATLAS aupres du LHC". Phd thesis, Université de la Méditerranée - Aix-Marseille II, 2006. http://tel.archives-ouvertes.fr/tel-00076100.
Pełny tekst źródłaChiou, Tze-Jiun, i 邱則鈞. "Storage Ageing Effects of Commercial LIB with Composite LMO-LNMC Cathode Material". Thesis, 2013. http://ndltd.ncl.edu.tw/handle/06763694358853878251.
Pełny tekst źródła大同大學
化學工程學系(所)
101
Storage ageing effects of commercial lithium-ion battery with composite LMO-LNMC cathode material has been investigated in this study. Sixteen sets of batteries were stored in four temperatures each with four depths of charge for six months. The batteries were charged and discharged at a constant current every month, and the impedances were determined in order to investigate the change inside the battery during charge and discharge, and to investigate the phenomenon of battery ageing. Results show that capacity decrease of the commercial batteries stored between 0℃ and 60℃and between 25% DOC and 100% DOC can be expressed as: where Q is dimensionless capacity [ - ], t is ageing time [day], DOC is depth of charge [ - ], T is temperature [K] and k1 is rate constant of capacity decrease [1/day]. The impedance increase can be expressed by where RE is the dimensionless impedance [ - ], k2 is the rate constant of impedance increase [1/day]. The experimental data of Q and RE are consistent with model calculations. Increasing storage temperature or depth of charge increases the ageing of battery, including capacity decrease and impedance increase. Battery ageing results in the shift of peak (valley) of the plot of dQ/dV vs V towards high voltage side, as well as in the decrease of the height (depth) of the peak (valley). The storage ageing effect is not obvious if the battery is stored below 25℃, regardless of the depth of charge. On the contrary, at temperature of 60℃ and depth of charge of 100%, the ageing effect is most obvious. At this condition, the capacity decreases by 16% and impedance increases by 70% after 6 months.
Chen, Hsin Yu, i 陳欣妤. "The Study on Peer-to-Peer Lending Platform in Taiwan -A Case of Lnb Company". Thesis, 2018. http://ndltd.ncl.edu.tw/handle/g5k7wh.
Pełny tekst źródłaNargaroo, Venodha. "The influence of age, sex, and socio-economic status on the performance of normal adults on the Luria-Nebraska Neuropsychological Battery (LNNB)". Thesis, 1991. http://hdl.handle.net/10413/5817.
Pełny tekst źródłaThesis (M.A.)-University of Durban-Westville, Durban, 1991.
Mallick, Kingshuk. "Probing phase transition and anisotropy in magnetic insulator based heterostructures employing magnon spin currents". Thesis, 2019. https://etd.iisc.ac.in/handle/2005/4857.
Pełny tekst źródłaHuang, Yi-Shu, i 黃益書. "Structural Analysis of GPS autoproteolysis of LNB-TM7 receptors – Characterization of the interaction between the extracellular α-subunit and the 7TM β-subunit". Thesis, 2007. http://ndltd.ncl.edu.tw/handle/23985514582628849440.
Pełny tekst źródła長庚大學
基礎醫學研究所
95
The classical G protein-coupled receptors (GPCRs) control many physiological responses through one polypeptide chain, which normally consists of a 7TM domain and a short extracellular domain. In contrast, the novel class B2 GPCRs (LNB-TM7) have been found to undergo post-translational autoproteolysis at the G protein-coupled receptor proteolytic site (GPS) located within a conserved Cys-rich domain that is upstream of the first transmembrane segment. Therefore, the GPS autoproteolysis of LNB-TM7 receptors produces constitutively two subunits, a large extracellular domain (α-subunit) resembling cell- adhesion protein and a TM7 domain (β-subunit) that is a typical TM7 moiety of GPCR, from a single polypeptide chain in the endoplasmic reticulum soon after the receptor biosynthesis. The proteolytic mechanism is mediated by a self-catalyzed reaction commonly employed by the N-terminal nucleophile hydrolase style autoproteolysis. Intriguingly, the cleaved α-subunit was shown to remain firmly on the cell membrane. It has long been believed that the tight plasma membrane association is due to the non-covalent interaction with β-subunit. Hence, the LNB-TM7 heterdimer receptors are thought to function through ligand binding or protein-protein interaction via the α-subunit, followed by signal transduction via the β-subunit. In a recent study, Volynski et al. demonstrated that the α-subunit and β-subunit of latrophilin, a LNB-TM7 receptor for -latrotoxin, do not normally interact on the cell membrane, but behave rather as separate entities responsible for ligand binding and cellular signaling, respectively. However, the functional roles of GPS autoproteolysis and the fate of the α-subunit and β-subunit on the cell membrane remain to be identified. Using EMR2, a well characterized membrane of the EGF-TM7 family as a model molecule, we investigated the fates of the cleaved α-subunit and β-subunit. We now demonstrate that the α-subunit is likely anchored on the membrane directly by itself and the β-subunit is partially localized in the lipid raft. Nevertheless, separated α-subunit and β-subunit can re-associate in soluble form. Hence, we propose a model where the agonist binding to the α-subunit induces re-association to the β-subunit in the lipid raft and promotes signal transduction via the β-subunit.
Wang, Kuei-Chen, i 王貴貞. "Structure-based catalytic mechanisms of galacto-N-biose/lacto-N-biose I phosphorylase and N-acetylhexosamine 1-kinase in the LNB/GNB pathway of Bifidobacterium longum". Thesis, 2014. http://ndltd.ncl.edu.tw/handle/61013302146238748954.
Pełny tekst źródła國立臺灣大學
生化科學研究所
102
Bifidobacteria, gram-positive anaerobic bacteria, feature a unique lacto-N-biose I (LNB)/galacto-N-biose (GNB) pathway to utilize LNB and GNB for colonization in the gastrointestinal tract of humans. The LNB/GNB pathway is encoded in a four-gene lnpABCD operon. Galacto-N-biose/lacto-N-biose I phosphorylase (GLNBP) encoded by the gene lnpA catalyzes phosphorolysis of LNB and GNB into galactose-1-phosphate (Gal-1P) and N-acetyl-D-hexoamine (GlcNAc/GalNAc) without ATP consumption. This maximizes the effectiveness of ATP production under anaerobic conditions. A novel N-acetylhexosamine 1-kinase (NahK) encoded by the gene lnpB then phosphorylates N-acetyl-D-hexoamine to N-acetylhexoamine 1-phosphate (GlcNAc-1P/GalNAc-1P). NahK has been extensively used in chemoenzymatic synthesis of carbohydrates. However, the molecular mechanisms for both GLNBP and NahK remain unclear. In this study, we wanted to determine the crystal structures of GLNBP and NahK in complex with substrates/products to gain insight into the catalytic mechanisms of these two enzymes. For GLNBP, crystal structures of GLNBP in complex with LNB/GNB were solved. Based on the structural information, GLNBP was proposed to proceed through an inverting phosphorolytic reaction by the direct nucleophilic attack of an inorganic phosphate at the anomeric carbon. For NahK, seven 3-D structures of NahK in complex with GlcNAc, GalNAc, GlcNAc-1P, GlcNAc/AMPPNP and GlcNAc-1P/ADP were solved. Based on these snapshot structures, a direct in-line phosphoryl transfer mechanism was proposed. The NahK structures presented here represent the first multiple-reaction complexes of the enzyme. The demonstration of the protein crystal structures and the elucidation of the catalytic mechanisms would provide useful information for expanding the utilizations of both GLNBP and NahK to a great extent.
Abrantes, Cristina Mamede. "Investigação em corpora informatizados de produções orais e escritas de aprendentes de PLNM: FAQ e orientações para a exploração de valências". Master's thesis, 2019. http://hdl.handle.net/10316/93366.
Pełny tekst źródłaA definição de um conjunto de perguntas (FAQ) para exploração de valências de pesquisa em corpora informatizados de produções escritas e orais de aprendentes de português língua não materna, a partir de uma plataforma digital, tem como principal objetivo orientar o utilizador na extração de dados consistentes destes acervos.Na génese deste projeto estão dois corpora que disponibilizam dados de aprendentes de português língua não materna com vista à sustentação empírica da investigação no âmbito da aquisição/aprendizagem de língua não materna, à fundamentação de práticas pedagógicas e, ainda, à criação de novos instrumentos didáticos: o corpus de Produções Escritas de Aprendentes de PL2 (PEAPL2_PLE) e o Corpus Oral de Português L2 (COral-Co).Estes corpora foram disponibilizados online a partir do TEITOK, uma plataforma que possibilita a pesquisa através do Corpus Query Processor (CQP), uma ferramenta flexível e eficiente, mas cuja rentabilização está condicionada, essencialmente, pelos processos de inserção e edição dos dados na plataforma e pela complexidade das expressões de pesquisa.Assim, as virtualidades da pesquisa em corpora informatizados de aprendentes, por um lado, e os constrangimentos à pesquisa que se podem colocar, por outro, motivaram a definição de um conjunto de FAQ com o objetivo de orientar o utilizador na exploração de corpora e rentabilizar as potencialidades da plataforma de pesquisa. As perguntas e as respetivas respostas encontram-se disponíveis para consulta online, na página de pesquisa de cada um dos referidos corpora, em dois formatos (PDF e mp4).Este modelo de construção de FAQ, baseado nos objetivos inerentes à construção de corpora e nas valências de pesquisa do CQP, potencia a atualização e o aperfeiçoamento deste tipo de help search e a sua replicação em corpora desenvolvidos a partir do TEITOK.
The definition of a set of questions (FAQ) for the exploration of research valences in computerised corpora of oral and written production of Portuguese as a Second or Foreign Language learners, on a digital platform, has as main goal to guide the user in the extraction of data from such collection.In the genesis of this project are two corpora that provide data of Portuguese as a Second or Foreign Language learners for the empirical support of the research in the scope of the acquisition/learning of a second or foreign language, the rationale of education practices, and the creation of didactic instruments: the Corpus de Produções Escritas de Aprendentes de PL2 (PEAPL2_PLE) and the Corpus Oral de Português L2 - Coimbra (COral-Co). These corpora have been made available online on TEITOK, a platform that allowed the research through the Corpus Query Processor (CQP), a flexible and efficient tool, but whose effectiveness is conditioned, mainly, by the data insertion and editing processes in the platform, and by the complexity of the research expressions.As such, the virtualities of the research in computerised corpora of learners, o non e hand, and the restraints that may occur on the research, on the other, have led to the definition of a set of FAQ with the purpose of guiding the user in the exploration of corpora and retrieving higher benefit from the research platform capabilities. The questions as the corresponding answers are available for online check in the research page of each of the mentioned corpora, in two formats (PDF and mp4).This model of FAQ construction, based on the goals inherent to the construction of corpora and the CQP’s research valences, empower the update and perfecting of this type of help search and its replication in corpora developed in TEITOK.