Artykuły w czasopismach na temat „LKB1/mTOR”
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Xiong, Yan, Ziye Xu, Yizhen Wang, Shihuan Kuang i Tizhong Shan. "Adipocyte-specific DKO of Lkb1 and mTOR protects mice against HFD-induced obesity, but results in insulin resistance". Journal of Lipid Research 59, nr 6 (10.04.2018): 974–81. http://dx.doi.org/10.1194/jlr.m081463.
Pełny tekst źródłaJiang, Wenxiao, Yijun Zhang, Ye Huang, Yunfeng Cheng i Zhigang Liu. "Effect of Hepatic Kinase B1 (LKB1) on Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells During Senescence". Journal of Biomaterials and Tissue Engineering 10, nr 2 (1.02.2020): 246–51. http://dx.doi.org/10.1166/jbt.2020.2247.
Pełny tekst źródłaYilmaz, Emrullah, Lauren Averett Byers, Lixia Diao, Uma Giri, Jayanthi Gudikote, You Hong Fan, Jing Wang i in. "Use of proteomic analysis of LKB1/AMPK/mTOR pathways to identify IGF-1R pathway upregulation with LKB1 loss or mTOR inhibition in NSCLC: Implications for targeted combinations." Journal of Clinical Oncology 30, nr 15_suppl (20.05.2012): 10612. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.10612.
Pełny tekst źródłaNishimura, Sadaaki, Masakazu Yashiro, Tomohiro Sera, Yurie Yamamoto, Yukako Kushitani, Atsushi Sugimoto, Shuhei Kushiyama i in. "Serine threonine kinase 11/liver kinase B1 mutation in sporadic scirrhous-type gastric cancer cells". Carcinogenesis 41, nr 11 (31.03.2020): 1616–23. http://dx.doi.org/10.1093/carcin/bgaa031.
Pełny tekst źródłaPaunovic, Verica, Stojan Peric, Irena Vukovic, Marina Stamenkovic, Emina Milosevic, Danijela Stevanovic, Milos Mandic i in. "Downregulation of LKB1/AMPK Signaling in Blood Mononuclear Cells Is Associated with the Severity of Guillain–Barre Syndrome". Cells 11, nr 18 (16.09.2022): 2897. http://dx.doi.org/10.3390/cells11182897.
Pełny tekst źródłaYang, Jing, Chengxian Xu, Joseph Lechner, Haley Walls i Kai Yang. "LKB1 regulates macrophage metabolism and functional polarization in immunomodulation". Journal of Immunology 210, nr 1_Supplement (1.05.2023): 168.14. http://dx.doi.org/10.4049/jimmunol.210.supp.168.14.
Pełny tekst źródłaZhou, Wei, Adam I. Marcus i Paula M. Vertino. "Dysregulation of mTOR activity through LKB1 inactivation". Chinese Journal of Cancer 32, nr 8 (5.08.2013): 427–33. http://dx.doi.org/10.5732/cjc.013.10086.
Pełny tekst źródłaBorkowsky, Sarah, Maximilian Gass, Azadeh Alavizargar, Johannes Hanewinkel, Ina Hallstein, Pavel Nedvetsky, Andreas Heuer i Michael P. Krahn. "Phosphorylation of LKB1 by PDK1 Inhibits Cell Proliferation and Organ Growth by Decreased Activation of AMPK". Cells 12, nr 5 (6.03.2023): 812. http://dx.doi.org/10.3390/cells12050812.
Pełny tekst źródłaRadu, Anca G., Sakina Torch, Florence Fauvelle, Karin Pernet-Gallay, Anthony Lucas, Renaud Blervaque, Véronique Delmas i in. "LKB1 specifies neural crest cell fates through pyruvate-alanine cycling". Science Advances 5, nr 7 (lipiec 2019): eaau5106. http://dx.doi.org/10.1126/sciadv.aau5106.
Pełny tekst źródłaLi, Yongqiang, Tao Sun, Shuxin Shen, Lixia Wang i Jifeng Yan. "LncRNA DYNLRB2-2 inhibits THP-1 macrophage foam cell formation by enhancing autophagy". Biological Chemistry 400, nr 8 (26.07.2019): 1047–57. http://dx.doi.org/10.1515/hsz-2018-0461.
Pełny tekst źródłaWang, Yuan, Shan Zhu, Hongtao Liu, Wen Wei, Yi Tu, Chuang Chen, Junlong Song i in. "Thyroxine Alleviates Energy Failure, Prevents Myocardial Cell Apoptosis, and Protects against Doxorubicin-Induced Cardiac Injury and Cardiac Dysfunction via the LKB1/AMPK/mTOR Axis in Mice". Disease Markers 2019 (18.12.2019): 1–10. http://dx.doi.org/10.1155/2019/7420196.
Pełny tekst źródłaAkasaka, Yasuyuki, Shun Hasei, Yukino Ohata, Machi Kanna, Yusuke Nakatsu, Hideyuki Sakoda, Midori Fujishiro i in. "Auraptene Enhances AMP-Activated Protein Kinase Phosphorylation and Thereby Inhibits the Proliferation, Migration and Expression of Androgen Receptors and Prostate-Specific Antigens in Prostate Cancer Cells". International Journal of Molecular Sciences 24, nr 21 (6.11.2023): 16011. http://dx.doi.org/10.3390/ijms242116011.
Pełny tekst źródłaShaw, Reuben J., Nabeel Bardeesy, Brendan D. Manning, Lyle Lopez, Monica Kosmatka, Ronald A. DePinho i Lewis C. Cantley. "The LKB1 tumor suppressor negatively regulates mTOR signaling". Cancer Cell 6, nr 1 (lipiec 2004): 91–99. http://dx.doi.org/10.1016/j.ccr.2004.06.007.
Pełny tekst źródłaLee, H. R., J. Kim, S. J. Yoo, J. A. Park i S. W. Kang. "POS0005 THE EFFECT OF LKB1 INHIBITION IN RA PATHOGENESIS". Annals of the Rheumatic Diseases 80, Suppl 1 (19.05.2021): 204.3–204. http://dx.doi.org/10.1136/annrheumdis-2021-eular.946.
Pełny tekst źródłaAznar, Nicolas, i Marc Billaud. "Primary Cilia Bend LKB1 and mTOR to Their Will". Developmental Cell 19, nr 6 (grudzień 2010): 792–94. http://dx.doi.org/10.1016/j.devcel.2010.11.016.
Pełny tekst źródłaZhao, Jimeng, Zhe Ma, Handan Zheng, Yan Huang, Luyi Wu, Huangan Wu, Yin Shi, Huirong Liu i Yanan Liu. "Effects of Herb-Partitioned Moxibustion on Autophagy and Immune Activity in the Colon Tissue of Rats with Crohn’s Disease". Evidence-Based Complementary and Alternative Medicine 2022 (28.01.2022): 1–12. http://dx.doi.org/10.1155/2022/3534874.
Pełny tekst źródłaXu, Ziye, Wenjing You, Fengqin Wang, Yizhen Wang i Tizhong Shan. "Elucidating the role of Lkb1 and mTOR in adipose tissue". Adipocyte 8, nr 1 (20.10.2018): 26–30. http://dx.doi.org/10.1080/21623945.2018.1535743.
Pełny tekst źródłaTreilleux, Isabelle, Monica Arnedos, Claire Cropet, Jean-Marc Ferrero, Sophie Abadie Lacourtoisie, Dominique Spaeth, Christelle Levy i in. "Predictive markers of everolimus efficacy in hormone receptor positive (HR+) metastatic breast cancer (MBC): Final results of the TAMRAD trial translational study." Journal of Clinical Oncology 31, nr 15_suppl (20.05.2013): 510. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.510.
Pełny tekst źródłaHuang, Xu, Stephan Wullschleger, Natalia Shpiro, Victoria A. McGuire, Kei Sakamoto, Yvonne L. Woods, Wendy Mcburnie, Stewart Fleming i Dario R. Alessi. "Important role of the LKB1–AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice". Biochemical Journal 412, nr 2 (14.05.2008): 211–21. http://dx.doi.org/10.1042/bj20080557.
Pełny tekst źródłaSun, Gao, Andrei I. Tarasov, James A. McGinty, Paul M. French, Angela McDonald, Isabelle Leclerc i Guy A. Rutter. "LKB1 deletion with the RIP2.Cre transgene modifies pancreatic β-cell morphology and enhances insulin secretion in vivo". American Journal of Physiology-Endocrinology and Metabolism 298, nr 6 (czerwiec 2010): E1261—E1273. http://dx.doi.org/10.1152/ajpendo.00100.2010.
Pełny tekst źródłaBi, Chengfeng, Chunsun Jiang, Xiaoxing Jiang, Xin Huang, Mario R. Fernandez, Javeed Iqbal, Robert E. Lewis, Wing Chung Chan, Timothy McKeithan i Kai Fu. "The Mir-17∼92 Cluster Activates mTORC1 Signaling in MCL by Targeting Multiple Regulators of the LKB1/AMPK/mTOR Pathway". Blood 120, nr 21 (16.11.2012): 5118. http://dx.doi.org/10.1182/blood.v120.21.5118.5118.
Pełny tekst źródłaHan, Dong, Shao-Jun Li, Yan-Ting Zhu, Lu Liu i Man-Xiang Li. "LKB1/AMPK/mTOR Signaling Pathway in Non-small-cell Lung Cancer". Asian Pacific Journal of Cancer Prevention 14, nr 7 (30.07.2013): 4033–39. http://dx.doi.org/10.7314/apjcp.2013.14.7.4033.
Pełny tekst źródłaJiménez-Mora, Eva, Beatriz Gallego, Sergio Díaz-Gago, Marina Lasa, Pablo Baquero i Antonio Chiloeches. "V600EBRAF Inhibition Induces Cytoprotective Autophagy through AMPK in Thyroid Cancer Cells". International Journal of Molecular Sciences 22, nr 11 (3.06.2021): 6033. http://dx.doi.org/10.3390/ijms22116033.
Pełny tekst źródłaXiao, Jia, Rui Guo, Man-Lung Fung, Emily C. Liong, Raymond Chuen Chung Chang, Yick-Pang Ching i George L. Tipoe. "Garlic-Derived S-Allylmercaptocysteine Ameliorates Nonalcoholic Fatty Liver Disease in a Rat Model through Inhibition of Apoptosis and Enhancing Autophagy". Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–11. http://dx.doi.org/10.1155/2013/642920.
Pełny tekst źródłaTzatsos, Alexandros, i Konstantin V. Kandror. "Nutrients Suppress Phosphatidylinositol 3-Kinase/Akt Signaling via Raptor-Dependent mTOR-Mediated Insulin Receptor Substrate 1 Phosphorylation". Molecular and Cellular Biology 26, nr 1 (1.01.2006): 63–76. http://dx.doi.org/10.1128/mcb.26.1.63-76.2006.
Pełny tekst źródłaShaw, R. J. "LKB1 and AMP-activated protein kinase control of mTOR signalling and growth". Acta Physiologica 196, nr 1 (maj 2009): 65–80. http://dx.doi.org/10.1111/j.1748-1716.2009.01972.x.
Pełny tekst źródłaGreen, Alexa S., Nicolas Chapuis, Thiago Trovati Maciel, Lise Willems, Mireille Lambert, Christophe Arnoult, Olivier Boyer i in. "The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation". Blood 116, nr 20 (18.11.2010): 4262–73. http://dx.doi.org/10.1182/blood-2010-02-269837.
Pełny tekst źródłaMoore, Timothy M., Xavier M. Mortensen, Conrad K. Ashby, Alexander M. Harris, Karson J. Kump, David W. Laird, Aaron J. Adams, Jeremy K. Bray, Ting Chen i David M. Thomson. "The effect of caffeine on skeletal muscle anabolic signaling and hypertrophy". Applied Physiology, Nutrition, and Metabolism 42, nr 6 (czerwiec 2017): 621–29. http://dx.doi.org/10.1139/apnm-2016-0547.
Pełny tekst źródłaLemoine, Manuela, Enrico Derenzini, Daniela Buglio, L. Jeffrey Medeiros, R. Eric Davis, Jiexin Zhang, Yuan Ji i Anas Younes. "The pan-deacetylase inhibitor panobinostat induces cell death and synergizes with everolimus in Hodgkin lymphoma cell lines". Blood 119, nr 17 (26.04.2012): 4017–25. http://dx.doi.org/10.1182/blood-2011-01-331421.
Pełny tekst źródłaJung, Taek-Yeol, Jae-Eun Ryu, Mi-Mi Jang, Soh-Yeon Lee, Gyu-Rin Jin, Chan-Woo Kim, Chae-Young Lee i in. "Naa20, the catalytic subunit of NatB complex, contributes to hepatocellular carcinoma by regulating the LKB1–AMPK–mTOR axis". Experimental & Molecular Medicine 52, nr 11 (listopad 2020): 1831–44. http://dx.doi.org/10.1038/s12276-020-00525-3.
Pełny tekst źródłaColombo, Marika, Matteo Demetrio Tripodi, Gabriel Caso, Elisa Perin, Mirko Marabese, Massimo Broggini i Elisa Caiola. "Abstract 6346: Identification of ERK inhibitor-based combinations targeting LKB1-mutated NSCLC". Cancer Research 82, nr 12_Supplement (15.06.2022): 6346. http://dx.doi.org/10.1158/1538-7445.am2022-6346.
Pełny tekst źródłaYang, Cong, Hongyu Ding, Yang Yang, Long Yang, Yun Yang, Meimiao Fang, Jin Ren, Ronggui Hu, Chengcheng Wang i Wujun Geng. "BAP1 regulates AMPK-mTOR signalling pathway through deubiquitinating and stabilizing tumour-suppressor LKB1". Biochemical and Biophysical Research Communications 529, nr 4 (wrzesień 2020): 1025–32. http://dx.doi.org/10.1016/j.bbrc.2020.05.223.
Pełny tekst źródłaRegina, Sandra, Jean-Baptiste Valentin, Sébastien Lachot, Bruno Giraudeau, Jerome Rollin i Yves Gruel. "Alterations of P53 and PTEN Genes Are Associated with Increased TF Expression and Reduced Survival in Non Small Cell Lung Cancer". Blood 112, nr 11 (16.11.2008): 1032. http://dx.doi.org/10.1182/blood.v112.11.1032.1032.
Pełny tekst źródłaTsai, Hui-Jen, Tsung-Ming Chang, Yan-Shen Shan, Pei-Yi Chu, Shih Sheng Jiang, Wen-Chun Hung, Yu-Lin Chen, Hsu-Chi Tu i Li-Tzong Chen. "The regulatory role of PTEN and LKB1 on mTOR pathway in pancreatic neuroendocrien tumors". Pancreatology 17, nr 3 (lipiec 2017): S11. http://dx.doi.org/10.1016/j.pan.2017.05.035.
Pełny tekst źródłaGreen, Alexa S., Nicolas Chapuis, Catherine Lacombe, Patrick Mayeux, Didier Bouscary i Jerome Tamburini. "LKB1/AMPK/mTOR signaling pathway in hematological malignancies: From metabolism to cancer cell biology". Cell Cycle 10, nr 13 (lipiec 2011): 2115–20. http://dx.doi.org/10.4161/cc.10.13.16244.
Pełny tekst źródłaLazo-de-la-Vega-Monroy, Maria-Luisa, Karen-Alejandra Mata-Tapia, Juan-Antonio Garcia-Santillan, Maria-Angelica Corona-Figueroa, Martha-Isabel Gonzalez-Dominguez, Hector-Manuel Gomez-Zapata, Juan-Manuel Malacara, Leonel Daza-Benitez i Gloria Barbosa-Sabanero. "Association of placental nutrient sensing pathways with birth weight". Reproduction 160, nr 3 (wrzesień 2020): 455–68. http://dx.doi.org/10.1530/rep-20-0186.
Pełny tekst źródłaÁvalos, Yenniffer, Jimena Canales, Roberto Bravo-Sagua, Alfredo Criollo, Sergio Lavandero i Andrew F. G. Quest. "Tumor Suppression and Promotion by Autophagy". BioMed Research International 2014 (2014): 1–15. http://dx.doi.org/10.1155/2014/603980.
Pełny tekst źródłaTanwar, Pradeep S., Tomoko Kaneko-Tarui, LiHua Zhang i Jose M. Teixeira. "Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of Sertoli cell polarity and spermatogenesis". Human Molecular Genetics 21, nr 20 (12.07.2012): 4394–405. http://dx.doi.org/10.1093/hmg/dds272.
Pełny tekst źródłaLiemburg-Apers, Dania C., Jori A. L. Wagenaars, Jan A. M. Smeitink, Peter H. G. M. Willems i Werner J. H. Koopman. "Acute stimulation of glucose influx upon mitoenergetic dysfunction requires LKB1, AMPK, Sirt2 and mTOR–RAPTOR". Journal of Cell Science 129, nr 23 (28.10.2016): 4411–23. http://dx.doi.org/10.1242/jcs.194480.
Pełny tekst źródłaVila-Bedmar, Rocio, Margarita Lorenzo i Sonia Fernández-Veledo. "Adenosine 5′-Monophosphate-Activated Protein Kinase-Mammalian Target of Rapamycin Cross Talk Regulates Brown Adipocyte Differentiation". Endocrinology 151, nr 3 (4.02.2010): 980–92. http://dx.doi.org/10.1210/en.2009-0810.
Pełny tekst źródłaShackelford, D. B., D. S. Vasquez, J. Corbeil, S. Wu, M. Leblanc, C. L. Wu, D. R. Vera i R. J. Shaw. "mTOR and HIF-1 -mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome". Proceedings of the National Academy of Sciences 106, nr 27 (18.06.2009): 11137–42. http://dx.doi.org/10.1073/pnas.0900465106.
Pełny tekst źródłaDong, Li-xia, Lin-lin Sun, Xia Zhang, Li Pan, Lin-juan Lian, Zhe Chen i Dian-sheng Zhong. "Negative regulation of mTOR activity by LKB1-AMPK signaling in non-small cell lung cancer cells". Acta Pharmacologica Sinica 34, nr 2 (26.11.2012): 314–18. http://dx.doi.org/10.1038/aps.2012.143.
Pełny tekst źródłaWildenberg, Manon, Anne Christine Vos, Marjolijn Duijvestein, Auke P. Verhaar, Daniel W. Hommes i Gijs R. van den Brink. "Tu1945 Induction of Autophagy Upon DC-T Cell Contact is Mediated by LKB1-AMPK-mTOR Signalling". Gastroenterology 142, nr 5 (maj 2012): S—884. http://dx.doi.org/10.1016/s0016-5085(12)63432-5.
Pełny tekst źródłaWildenberg, M. E., A. C. Vos, M. Duijvestein, A. Verhaar, G. van den Brink i D. W. Hommes. "OP03 Induction of autophagy upon DC-T cell contact is mediated by LKB1 AMPK mTOR signalling". Journal of Crohn's and Colitis 6 (luty 2012): S2. http://dx.doi.org/10.1016/s1873-9946(12)60004-x.
Pełny tekst źródłaHan, Jie, Huimin Liang, Derun Tian, Jianying Du, Qiming Wang, Pengjiao Xi, Haomin Wang i Yongmei Li. "mTOR remains unchanged in diet-resistant (DR) rats despite impaired LKB1/AMPK cascade in adipose tissue". Biochemical and Biophysical Research Communications 476, nr 4 (sierpień 2016): 333–39. http://dx.doi.org/10.1016/j.bbrc.2016.05.123.
Pełny tekst źródłaBorthakur, Gautam, Michael Andreeff, Kevin R. Coombes, Yi Hua Qiu, Seshagiri Duvvuri, Nianxiang Zhang, Vivian Ruvolo i in. "High Expression of Autophagy Related Proteins Negatively Impacts Clinical Outcomes in Acute Myelogenous Leukemia–Time to Target Autophagy to Improve Therapy Outcomes?" Blood 118, nr 21 (18.11.2011): 2513. http://dx.doi.org/10.1182/blood.v118.21.2513.2513.
Pełny tekst źródłaHou, Yawei, Yameng Li, Yichuan Wang, Wenpu Li i Zhenwei Xiao. "Screening and Analysis of Key Genes in miRNA-mRNA Regulatory Network of Membranous Nephropathy". Journal of Healthcare Engineering 2021 (16.11.2021): 1–13. http://dx.doi.org/10.1155/2021/5331948.
Pełny tekst źródłaGoel, MadhuMati, Annu Makker, AbbasAli Mahdi, Vikram Bhatia, Vinita Das, Anjoo Agarwal i Amita Pandey. "PI3K/Akt/mTOR signaling & its regulator tumour suppressor genes PTEN & LKB1 in human uterine leiomyomas". Indian Journal of Medical Research 143, nr 7 (2016): 112. http://dx.doi.org/10.4103/0971-5916.191808.
Pełny tekst źródłaNguyen, H. B., J. T. Babcock, C. D. Wells i L. A. Quilliam. "LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap". Oncogene 32, nr 35 (1.10.2012): 4100–4109. http://dx.doi.org/10.1038/onc.2012.431.
Pełny tekst źródłaLai, L. P., B. N. Lilley, J. R. Sanes i A. P. McMahon. "Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formation". Proceedings of the National Academy of Sciences 110, nr 48 (11.11.2013): 19450–55. http://dx.doi.org/10.1073/pnas.1309001110.
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