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Artykuły w czasopismach na temat "Kidneys"

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Churchill, P. C., M. C. Churchill i A. K. Bidani. "Kidney cross transplants in Dahl salt-sensitive and salt-resistant rats". American Journal of Physiology-Heart and Circulatory Physiology 262, nr 6 (1.06.1992): H1809—H1817. http://dx.doi.org/10.1152/ajpheart.1992.262.6.h1809.

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Previous kidney cross-transplant studies have demonstrated that the genotype of the kidney plays a role in determining the blood pressure of the recipient in Dahl salt-sensitive (S) and salt-resistant (R) rats. The present studies were designed to elucidate this role. Kidney cross transplants were performed in unilaterally nephrectomized male recipients (John Rapp strains), such that each rat had a native kidney and a transplanted kidney of the opposite genotype. S and R rats with a native kidney and a transplanted kidney of the same genotype served as controls. After 4 wk on a 7.8% NaCl diet, rats were anesthetized and renal clearance studies were performed. S kidneys had lower glomerular filtration rate (GFR) and renal plasma flow (RPF) than R kidneys, and these differences were determined by the kidney's genotype rather than the recipient's, since S kidneys in R recipients tended to have lower GFR and RPF than R kidneys in S recipients. In contrast, independent of the kidney's genotype, the kidneys in S rats tended to have higher fractional excretion of H2O and Na (FEH2O and FENa) than the kidneys in R rats. Thus there were genetically determined differences in renal function between S and R rats; some (RPF and GFR) were intrinsic to the kidney, whereas others (FEH2O and FENa) were intrinsic to the host.(ABSTRACT TRUNCATED AT 250 WORDS)
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Vlajkovic, Slobodan, Marija Dakovic-Bjelakovic, Rade Cukuranovic i Jasmina Popovic. "Evaluation of absolute volume of human fetal kidney's cortex and medulla during gestation". Vojnosanitetski pregled 62, nr 2 (2005): 107–11. http://dx.doi.org/10.2298/vsp0502107v.

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Background. Human fetal kidney is quite different from the mature kidney, both macroscopically and hystologically. Lobulated surface of the human fetal kidney reflects its inner organization. Aim. To determine the fetal kidneys' volume according to the gestational age, to establish periods of their maximal and minimal growth and to compare these values for various gestational ages. Methods. Forty five human fetal kidneys aged from IV to X lunar months were analyzed. Kidneys were divided into nine groups according to their gestational age. The volumes of cortex and medulla were determined using stereological methods. The results were statistically analyzed and the periods of significant growth of these structures were marked. Results. Fetal kidney's cortex and medulla grew continually with a very high coefficient of linear correlation with crown-rump length. The cortex/medulla ratio was minimal in the first half of V lunar month, when medulla grew most rapidly and it was maximal immediately before birth, when cortex achieved its maximum. Conclusion. This study was an effort to provide some parameters which would help in the future investigations of the development of human fetal kidney.
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V. M. Monastyrsʹkyy. "CHARACTERISTICS OF THE KIDNEY PARAMETERS ACCORDING TO THE DATA OF MAGNETIC RESONANCE IMAGING OF PATIENTS WITH UROLITHIASIS IN PERSONS WITH A SINGLE KIDNEY". Clinical anatomy and operative surgery 17, nr 3 (28.08.2018): 38–43. http://dx.doi.org/10.24061/1727-0847.17.3.2018.6.

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Urolithiasis is one of the most common diseases of the kidneys and urinary tract. The purpose of the study is to compare the size of a single kidney in patients with urolithiasis with parameters of the kidneys of patients with two kidneys who don’t have any diseases of the kidneys and urinary tract. A comprehensive examination of 84 patients with urolithiasis and single kidney and 65 patients with two kidneys who didn’t have any kidney and urinary tract diseases were conducted. The research was carried out on a magnetic resonance tomography Philips Intera-1,5T (standard magnetic resonance protocol included scanning in sagittal, frontal and axial projections to obtain T1 images). The length of the right single kidney is statistically significantly greater (1.18 times) in men with urolithiasis than in men with two kidneys who did not have any kidney and urinary tract disorders (p<0.05). The width, thickness and volume of the kidneys were also statistically significantly larger respectively 1.25 times, 1.27 times and 2.01 times (p <0.05). The parameters of the kidney (length, width, thickness and volume) were larger, respectively, in 1.21 times, 1.26 times, 1.26 times and 1.93 times in women with the single right kidney with urolithiasis. Conclusion. The morphometric parameters of a single kidney in patients with urolithiasis (length, width, thickness and volume) were statistically significantly different from those in patients with two kidneys who don’t have any kidney and urinary tract disorders. The measure of the volume of the right single kidney in men suffering from urolithiasis was the highest (p <0.05) in comparison with the same parameters in patients with two kidneys who don’t have any kidney and urinary tract disorders.
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Potluri, Vishnu S., David S. Goldberg, Sumit Mohan, Roy D. Bloom, Deirdre Sawinski, Peter L. Abt, Emily A. Blumberg i in. "National Trends in Utilization and 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys". Journal of the American Society of Nephrology 30, nr 10 (12.09.2019): 1939–51. http://dx.doi.org/10.1681/asn.2019050462.

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BackgroundRecent pilot trials have demonstrated the safety of transplanting HCV-viremic kidneys into HCV-seronegative recipients. However, it remains unclear if allograft function is impacted by donor HCV-viremia or recipient HCV-serostatus.MethodsWe used national United States registry data to examine trends in HCV-viremic kidney use between 4/1/2015 and 3/31/2019. We applied advanced matching methods to compare eGFR for similar kidneys transplanted into highly similar recipients of kidney transplants.ResultsOver time, HCV-seronegative recipients received a rising proportion of HCV-viremic kidneys. During the first quarter of 2019, 200 HCV-viremic kidneys were transplanted into HCV-seronegative recipients, versus 69 into HCV-seropositive recipients, while 105 HCV-viremic kidneys were discarded. The probability of HCV-viremic kidney discard has declined over time. Kidney transplant candidates willing to accept a HCV-seropositive kidney increased from 2936 to 16,809 from during this time period. When transplanted into HCV-seronegative recipients, HCV-viremic kidneys matched to HCV-non-viremic kidneys on predictors of organ quality, except HCV, had similar 1-year eGFR (66.3 versus 67.1 ml/min per 1.73 m2, P=0.86). This was despite the much worse kidney donor profile index scores assigned to the HCV-viremic kidneys. Recipient HCV-serostatus was not associated with a clinically meaningful difference in 1-year eGFR (66.5 versus 71.1 ml/min per 1.73 m2, P=0.056) after transplantation of HCV-viremic kidneys.ConclusionsBy 2019, HCV-seronegative patients received the majority of kidneys transplanted from HCV-viremic donors. Widely used organ quality scores underestimated the quality of HCV-viremic kidneys based on 1-year allograft function. Recipient HCV-serostatus was also not associated with worse short-term allograft function using HCV-viremic kidneys.
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Emond, C., J. L. Bascands, J. Rakotoarivony, F. Praddaude, G. Bompart, C. Pecher, J. L. Ader i J. P. Girolami. "Glomerular B2-kinin-binding sites in two-kidney, one-clip hypertensive rats". American Journal of Physiology-Renal Physiology 260, nr 5 (1.05.1991): F626—F634. http://dx.doi.org/10.1152/ajprenal.1991.260.5.f626.

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To extend our recent observations of the possible downregulation of glomerular B2-kinin-binding sites, we investigated density (Bmax) of bradykinin (BK)-binding sites in glomerular membranes of both the clipped (C) and nonclipped (NC) kidneys of two-kidney, one-clip (2K-1C) Goldblatt hypertensive rats, in relation to tissue kallikrein activity and glomerular three-dimensional structure. Compared with the Bmax of sham-operated (SO) kidney (31.8 +/- 7 fmol/mg protein), a significant increase in Bmax was observed in glomeruli of both kidneys in hypertensive rats, the Bmax being higher in glomeruli of NC than in C kidneys (98 +/- 11 vs. 59 +/- 12 fmol/mg protein). NC kidney compensatory hypertrophy was expressed by an increase in glomerular diameter, surface area, and volume. When expressed per unit of area or volume, Bmax in NC kidneys remained significantly higher than in both C and SO kidneys. Increased Bmax in both kidneys of 2K-1C rats was associated with a decreased intrarenal level of kallikrein. We also examined prostaglandin (PG) E2 release by isolated glomeruli from SO, C, and NC kidneys as a possible biological effect induced by BK. Whereas C kidney released more PGE2 than NC kidney under basal conditions, addition of BK (10 nM) induced greater PGE2 production in NC kidney consistent with the difference in Bmax between C and NC kidneys. These results suggest a possible downregulation of glomerular B2-binding sites by bradykinin, which may explain the difference between SO and C kidneys.(ABSTRACT TRUNCATED AT 250 WORDS)
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Gadade, Varsha, Wasim Hiroli i Sunil Mathew. "Examining congenital renal abnormalities in adult cadavers: an observational study". Perspectives in Medical Research 11, nr 1 (30.05.2023): 74–78. http://dx.doi.org/10.47799/pimr.1101.12.

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Abstract To know the percentages of incidences of various types of congenital anomalies of the renal system, an observational study was conducted at Departments of Anatomy of three medical colleges by dissection method and observation was made on dissected specimens for the presence of morphological anomalies in kidneys and the anatomical locations of kidneys and ureters. We found various types of renal anomalies like agenesis of kidney, nodular kidney and constricted (small) kidney location, ectopic kidneys bilateral polycystic kidneys. Conclusion: Various abnormalities were found in this study and so, knowledge of such anomalies of kidneys not only to anatomists but to all clinicians especially to urologists and nephrologists and radiologists.
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Dharmaratne, RW. "Exploring the role of excess fluoride in chronic kidney disease: A review". Human & Experimental Toxicology 38, nr 3 (25.11.2018): 269–79. http://dx.doi.org/10.1177/0960327118814161.

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This review covers nearly 100 years of studies on the toxicity of fluoride on human and animal kidneys. These studies reveal that there are direct adverse effects on the kidneys by excess fluoride, leading to kidney damage and dysfunction. With the exception of the pineal gland, the kidney is exposed to higher concentrations of fluoride than all other soft tissues. Therefore, exposure to higher concentrations of fluoride could contribute to kidney damage, ultimately leading to chronic kidney disease (CKD). Among major adverse effects on the kidneys from excessive consumption of fluoride are immediate effects on the tubular area of the kidneys, inhibiting the tubular reabsorption; changes in urinary ion excretion by the kidneys disruption of collagen biosynthesis in the body, causing damages to the kidneys and other organs; and inhibition of kidney enzymes, affecting the functioning of enzyme pathways. This review proposes that there is a direct correlation between CKD and the consumption of excess amounts of fluoride. Studies particularly show immediate adverse effects on the tubular area of human and animal kidneys leading to CKD due to the consumption of excess fluoride. Therefore, it is very important to conduct more investigations on toxicity studies of excess fluoride on the human kidney, including experiments using human kidney enzymes, to study more in depth the impact of excess fluoride on the human kidney. Further, the interference of excess fluoride on collagen synthesis in human body and its effect on human kidney should also be further investigated.
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Borda, Bernadett, Edit Szederkényi, Aurél Ottlakán, Éva Kemény, Viktor Szabó, Zoltán Hódi i György Lázár. "Banff-score-változások a marginális donorokból származó veséknél". Orvosi Hetilap 157, nr 8 (luty 2016): 298–301. http://dx.doi.org/10.1556/650.2016.30346.

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Introduction: Despite an increase in the number of cadaver donors and the number of overall organ transplantations, the dramatic increase in the waiting list makes it necessary to reconsider donor criteria. Aim: The authors examined whether differences could exist in the function and/or morphology of transplanted kidneys originated from marginal and ideal donors one and five years after transplantation. Method: Kidney function and histopathologic findings were analysed and compared one and 5 years after transplantation in 97 patients having marginal donor kidneys and 178 patients who received ideal donor kidneys. Results: Serum creatinine level was significantly higher (p = 0.0001) and estimated glomerular filtration rate was significantly lower (p = 0.003) in patients having marginal donor kidneys as compared to those with ideal donor kidneys 5 years after transplantation. Morphological changes in the transplated kidneys such as tubulitis (p = 0.014) and interstitial inflammation (p = 0.025) were significantly more frequently present in patients with marginal donor kidneys than in those with ideal donor kidneys one year after transplantation. Conclusion: Despite an absence of differences in kidney function one year after kidney transplantation between patients having marginal and ideal donor kidneys, morphologic differences in the transplanted kidneys can be detected between the two groups of patients. Orv. Hetil., 2016, 157(8), 298–301.
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Reshma Dayma. "Machine Learning Algorithms as a Boon for Chronic Kidney Disease Prediction". Journal of Electrical Systems 20, nr 3 (30.04.2024): 499–508. http://dx.doi.org/10.52783/jes.2977.

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Chronic kidney disease (CKD) is one type of condition where kidney function damage over several month or year. In body, kidney’s main task is to filter impurities and waste from blood which is flush out from body in form of urine. But because of some condition or diseases, in which the kidneys are damaged and cannot filter blood as well as it should. People with kidney disease may not feel ill or notice any symptoms in early stage but it is very serious problem as it may lead to complete failure of kidneys. Machine learning (ML) techniques are used for prediction. Here we have created machine learning model for CKD prediction. We have use three algorithms, logistic regression, support vector machine (SVM) and random forest with feature selection technique and finally applied bagging method on it. we have applied this model on chronic kidney dataset which have derived from UCI machine learning repository. This model predict person have chronic kidney disease or not.
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WILLIS, LYNN R., ANDREW P. EVAN, BRET A. CONNORS, PHIL BLOMGREN, NAOMI S. FINEBERG i JAMES E. LINGEMAN. "Relationship between Kidney Size, Renal Injury, and Renal Impairment Induced by Shock Wave Lithotripsy". Journal of the American Society of Nephrology 10, nr 8 (sierpień 1999): 1753–62. http://dx.doi.org/10.1681/asn.v1081753.

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Abstract. The relationship between kidney size and impaired renal function induced by shock-wave lithotripsy (SWL) was examined in 6- and 10-wk-old anesthetized pigs. Each pig received 2000 shock waves, 24 kV, or sham SWL to the lower pole calyx of one kidney. Bilateral GFR, renal plasma flow (RPF), and para-aminohippurate extraction was measured 1 h before and 1 and 4 h after SWL. The kidneys were then removed for morphometric analysis. Mean kidney weights were 66.1 ± 2.7 g (n = 9) and 103.1 ± 3.3 g (n = 8) in the SWL groups, and 60.1 ± 2.6 g (n = 9) and 82.3 ± 4.0 g (n = 9) in the sham-SWL groups. SWL-induced lesions occupied a significantly greater volume of the small kidneys (6.1 ± 1.7 vol % versus 1.5 ± 0.2 vol % in the large kidneys). RPF was significantly reduced by SWL in small and large kidneys, but to a significantly greater extent in small kidneys. RPF was also significantly reduced in the contralateral kidneys of both groups, but only at 1 h after SWL. SWL significantly reduced GFR to similar degrees in both kidneys of both groups, regardless of kidney size. Para-aminohippurate extraction was likewise reduced to similar degrees in both groups, but this effect was evident only in the SWL-treated kidneys, and only in the pole to which the shock waves had been applied. The injury induced by SWL affected a larger fraction of small kidneys than large ones, and the renal vasoconstriction induced by SWL was greatest in small kidneys.
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Rozprawy doktorskie na temat "Kidneys"

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Tang, Chi-wai Sydney. "The many facets of the renal proximal tubular epithelial cell in human". Click to view the E-thesis via HKUTO, 2005. http://sunzi.lib.hku.hk/hkuto/record/B31992468.

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Tang, Chi-wai Sydney, i 鄧智偉. "The many facets of the renal proximal tubular epithelial cell inhuman". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B31992468.

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Wallin, Lena. "99m Tc-DMSA renal scintigraphy in the diagnosis and follow-up of acute pyelonephritis in children". Lund : Dept. of Clinical Physiology, Lund University, 1997. http://books.google.com/books?id=6kFsAAAAMAAJ.

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Melnychuk, S. P. "Emoxypine prevents structural changes in kidneys in rats with acute kidney injury". Thesis, БДМУ, 2021. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18906.

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Antoniv, A. A. "Kidneys functional status in patients with chronic kidney disease and nonalcoholic steatohepatitis". Thesis, БДМУ, 2020. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18082.

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RYLANDER, LESLIE ANN. "PROXIMAL TUBULE SUSPENSIONS FROM RABBIT KIDNEY: AN IN VITRO SYSTEM FOR THE STUDY OF NEPHROTOXICITY". Diss., The University of Arizona, 1986. http://hdl.handle.net/10150/183785.

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The proximal tubule of the renal cortical nephron is highly susceptible to intoxication by chemical agents. An in vitro system was developed to study directly the effects of nephrotoxic chemicals on this renal sub-organ fraction without the complication of extrarenal factors. Segments of proximal tubules were isolated by a mechanical method from the kidneys of young rabbits. Tubules obtained by this method retained biochemical, functional, and morphological features comparable to those existing in vivo. Preliminary acute susceptibility studies demonstrated that the isolated proximal tubule segments were sensitive to a variety of known nephrotoxic agents that target the proximal tubule. These agents include halogenated hydrocarbons, heavy metals, and a halogenated vinyl cysteine conjugate. Incubation conditions were optimized to maintain the viability of proximal tubule suspensions for up to four hours. Longer incubation times made it possible to establish a chronology of early tubule responses to chemical intoxication. Long term incubation of proximal tubule suspensions with two model nephrotoxins, cadmium chloride and S-(trans-1,2-dichlorovinyl)-L-cysteine, produced in vitro tubule response patterns similar to those reported in vivo for these agents. While not entirely representative of in vivo exposure conditions, suspensions of isolated proximal tubules are an easily obtained system that proved equally applicable as a screening technique for nephrotoxic compounds or as an in vitro system for delineating proximal tubule response to chemical insult.
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Shweta, Amany 1971. "The renal sympathetic nerves : implications for vascular remodelling in the SHR kidney". Monash University, Dept. of Physiology, 2001. http://arrow.monash.edu.au/hdl/1959.1/8351.

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Antoniv, A. A. "The kidneys functional state in chronic kidney disease in patients with nonalcoholic steatohepatitis". Thesis, БДМУ, 2021. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18584.

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Chambers, Jeanette Kay. "Knowledge, attitudes, and uncertainty of adult patients with decreased kidney function". Connect to resource, 1991. http://rave.ohiolink.edu/etdc/view.cgi?acc%5Fnum=osu1260191207.

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Meyer, Amanda Jane. "The impact of prenatal glucocorticoid exposure on the ovine kidney". University of Western Australia. School of Women's and Infants' Health, 2006. http://theses.library.uwa.edu.au/adt-WU2006.0105.

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[Truncated abstract] In obstetric practice, pregnant women at risk of pre-term delivery between 24 and 34 weeks of gestation are administered synthetic glucocorticoids (betamethasone or dexamethasone) to induce fetal organ maturation. During this gestational period, the fetal kidney is undergoing a phase of rapid organogenesis with an increase in renal growth and active nephrogenesis occurring. The studies comprising this thesis examine the effects of prenatal betamethasone exposure on the fetal and adult ovine kidney. The central hypothesis of these studies was that exposure of the fetal kidney to betamethasone in late gestation would change renal structure and induce long-term alterations in the expression of glucocorticoid-sensitive genes and proteins. In the fetal studies, pregnant Merino ewes bearing single fetuses received single or repeated-weekly intra-muscular (i.m.) injections of betamethasone (0.5 mg/kg body weight) or saline commencing on day 104 of gestation (term is 150 days). Kidneys were collected from fetuses at 109, 116, 121 and 146 days of gestation (d). Using gold standard unbiased stereological techniques, the physical disector/fractionator method, total glomerular (nephron) number and glomerular volume were determined in 146 d fetal kidneys exposed to repeated maternal saline or betamethasone administration. In the adult study, kidneys were collected from 3.5-year-old sheep that had been exposed to ... In this thesis I have demonstrated that renal growth restriction as a result of betamethasone exposure is associated with a reduction in fetal nephron endowment. Although betamethasone does not appear to consistently alter nephron number or glomerular size, it may indirectly affect total nephron endowment through effects on renal growth. I have also provided evidence which suggests that lategestation betamethasone exposure in sheep does not program permanent alterations in the renal expression of genes or proteins involved in glucocorticoid hormone action or components of the renin-angiotensin system. Therefore, exposure of the fetal kidney to betamethasone during nephrogenesis may alter renal structure if kidney growth is perturbed; however, there are no persistent alterations in the expression of glucocorticoid-sensitive genes. These findings are consistent with the preservation of normal basal blood pressure in the adult sheep I studied and with the limited results from human studies of late-gestation maternal glucocorticoid administration.
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Książki na temat "Kidneys"

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Eaton, Douglas C. Vander's renal physiology. Wyd. 7. New York: McGraw-Hill Medical, 2009.

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Larre, Claude. The kidneys. Cambridge, U.K: Monkey Press, 1992.

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Adamec, Christine. The encyclopedia of kidney diseases and disorders. New York, USA: Facts on File, 2012.

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Stewart, Cameron J., i Rees A. J, red. Oxford textbook of clinical nephrology. Oxford: Oxford University Press, 1992.

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Danziger, John. Renal physiology: A clinical approach. Baltimore, MD: Lippincott Williams & Wilkins, 2012.

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1943-, Morris Peter J., red. Kidney transplantation: Principles and practice. Wyd. 3. Philadelphia: Saunders, 1988.

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D, Catto Graeme R., red. Transplantation. Dordrecht: Kluwer Academic Publishers, 1989.

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A, Porter K., Pugh R. C. B i Ansell I. D. 1938-, red. The Kidneys. Wyd. 3. Edinburgh: Churchill Livingstone, 1992.

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Endre, Krüger, i Hahn Kelemen, red. Nephrology, dialysis, transplantation. Hauppauge, N.Y: Nova Science Publishers, 2009.

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Wardener, H. E. De. The kidney: An outline of normal and abnormal function. Edinburgh: Churchill-Livingstone, 1985.

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Części książek na temat "Kidneys"

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Srivastava, Aneesh, i Rahul Jena. "Horseshoe Kidneys, Polycystic Kidney, and Post-transplant Kidneys". W Minimally Invasive Percutaneous Nephrolithotomy, 285–93. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-6001-6_27.

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Treves, S. Ted, Alan B. Packard i Frederick D. Grant. "Kidneys". W Pediatric Nuclear Medicine and Molecular Imaging, 283–333. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-9551-2_12.

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Pickuth, Dirk. "Kidneys". W Essentials of Ultrasonography, 133–57. Berlin, Heidelberg: Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-642-79579-4_9.

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Gedroyc, Wladyslaw, i Sheila Rankin. "Kidneys". W Practical CT Techniques, 52–55. London: Springer London, 1992. http://dx.doi.org/10.1007/978-1-4471-3275-2_16.

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Alerhand, Stephen. "Kidneys". W Atlas of Handheld Ultrasound, 149–53. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-73855-0_28.

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Luboldt, W., i G. P. Krestin. "Kidneys". W Abdominal and Pelvic MRI, 149–66. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-18194-8_12.

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Daneman, Alan. "Kidneys". W Pediatric Body CT, 145–71. London: Springer London, 1987. http://dx.doi.org/10.1007/978-1-4471-3137-3_11.

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Treves, S. T., M. Majd, A. Kuruc, A. B. Packard i W. Harmon. "Kidneys". W Pediatric Nuclear Medicine, 339–99. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4757-4205-3_17.

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Ramalho, Miguel, António Matos, Ersan Altun, Larissa Braga i Richard C. Semelka. "Kidneys". W Abdominal-Pelvic MRI, 851–1003. Oxford, UK: John Wiley & Sons, Ltd, 2015. http://dx.doi.org/10.1002/9781119012979.ch9.

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Harisinghani, Mukesh G., i Arumugam Rajesh. "Kidneys". W Genitourinary Imaging, 23–80. London: Springer London, 2014. http://dx.doi.org/10.1007/978-1-4471-4772-5_2.

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Streszczenia konferencji na temat "Kidneys"

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Yan, Feng, Chen Wang, Bornface M. Mutembei, Zaid A. Alhajeri, Qinghao Zhang, Ebenezer Raj Selvaraj Mercyshalinie, Zhongxin Yu, Yu Chen, Kar-Ming Fung i Qinggong Tang. "Evaluation of Human Kidney for Transplantation Using Polarization-Sensitive Optical Coherence Tomography". W Imaging Systems and Applications. Washington, D.C.: Optica Publishing Group, 2023. http://dx.doi.org/10.1364/isa.2023.itu5e.3.

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We confirmed that human kidneys have various quality evaluations on different locations from histological scores. Polarization-sensitive optical coherence tomography (PS-OCT) can noninvasively provide multiple evaluations for the whole kidney for the feasibility of transplantation.
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Myronenko, Andriy, i Ali Hatamizadeh. "Edge-Aware Network for Kidneys and Kidney Tumor Semantic Segmentation". W 2019 Kidney Tumor Segmentation Challenge: KiTS19. University of Minnesota Libraries Publishing, 2019. http://dx.doi.org/10.24926/548719.009.

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Chen, Pan, Chenghai Xu, Jie He, Chengwei Sun, Yingying Ma i Fenglong Sun. "Using Two-stage Network to Segment Kidneys and Kidney Tumors". W 2019 Kidney Tumor Segmentation Challenge: KiTS19. University of Minnesota Libraries Publishing, 2019. http://dx.doi.org/10.24926/548719.049.

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Suh, Ga Young, Gilwoo Choi, Mary Draney Blomme i Charles A. Taylor. "Quantification of Three-Dimensional Motion of the Renal Arteries Using Image-Based Modeling Techniques". W ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176291.

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Stents implanted to treat renal artery stenosis are vulnerable to stent fracture and thrombosis [1–3]. We hypothesize that the motion of the renal arteries during respiration is a possible cause of stent fracture or in-stent restenosis. However, the respiratory motion of the renal arteries and the kidneys is poorly understood. Using magnetic resonance imaging data we previously quantified the two-dimensional deformation of the renal arteries and demonstrated that respiration-induced kidney motion results in vessel bending near the ostia [4]. In this study we quantified the complex three-dimensional motion of the renal arteries and kidneys over the respiratory cycle using magnetic resonance angiography data and imaged-based modeling methods. We provide quantitative information on anatomic changes to the renal arteries that may provide data to design improved pre-clinical, benchtop tests for renal stents.
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Sauliutė, Gintarė, Milda Stankevičiūtė, Gintaras Svecevičius, Janina Baršienė i Roberta Valskienė. "Assessment of heavy metals bioconcentration factor (BCF) and genotoxicity response induced by metal mixture in Salmo salar tissues". W Environmental Engineering. VGTU Technika, 2017. http://dx.doi.org/10.3846/enviro.2017.043.

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The aim of this study was to evaluate metals bioconcentration factor (BCF) in gills, liver, kidneys and muscle in relation with genotoxicity effects of metal mixture in peripheral blood, kidneys, gills and liver erythrocytes of the Atlantic salmon (Salmo salar). Fish were exposed to maximum-permissible waterborne concentrations of Zn – 0.1, Cu – 0.01, Ni – 0.01, Cr – 0.01, Pb – 0.005 and Cd – 0.005 mg/L, respectively for 7 and 14 days. Genotoxicity was studied using the micronucleus test. In addition, erythrocyte nuclear abnormalities (ENAs) were analysed. Our study indicates that metal BCF in Atlantic salmon is tissue-dependent. Based on the BCF classification scale, the relatively low values of metals bioconcentration were assessed, except for Zn (gills) and Cu (liver) (359.6 and 594.0, respectively). Zn intensively concentrated in fish tissues, while Pb – least of all. Overall, metals were concentrated mostly in the liver, least – in the muscle. Significant differences among BCF values of Pb in gills and muscle and Cd in gills were measured between 7 and 14 d exposure groups. Treatment with metal mixture significantly increased micronucleus frequencies after 7 d of exposure in liver and peripheral blood erythrocytes. Significant genotoxicity response was not observed after 14 d treatment. The erythrocytic nuclei abnormalities determined in S. salar blood were nuclear bud on filament (NBf), nuclear bud (NB), blebbed (BL), kidney shaped, vacuolated (VacNuc), 8-shaped nuclei and fragmented-apoptotic (FA) erythrocytes. Significant elevation in total ENAs level was detected in kidneys and liver erythrocytes after 7 d treatment, while after 14 d – in gills and kidneys erythrocytes. No significant differences among analysed responses were measured between 7 and 14 d exposure groups, except total ENAs level in liver erythrocytes.
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Chu, Sauman, Allyson Hart i Marilyn Bruin. "A patient-centered approach in designing a kidney transplant decision aid". W AHFE 2023 Hawaii Edition. AHFE International, 2023. http://dx.doi.org/10.54941/ahfe1004234.

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The kidney transplant decision aid tool (https://www.srtr.org/tools/kidney-transplant-decision-aid/) was designed, created, and included as part of the Scientific Registry of Transplant Recipients (SRTR) resource website. The decision aid tool was created with input from patients with kidney disease and the doctors who care for them. An extensive information gathering and testing process with user-centered approach was implemented. Ten interviews and 4 focus group discussion sessions were held with an average of 4.5 patients in each group to gather preliminary design and content directions. Two additional focus groups with a total of 12 kidney transplant providers and 4 additional national focus group discussions with a total of 19 patients were held afterward to discuss the created content and design approach. Finally, 15 individual patient testing sessions were conducted to refine the content, design, and navigation of the tool. The tool is intended to be used during patient’s visit with their doctor as the patient learns about kidney transplant. Our goal is to provide informative materials to empower patients by helping them understand treatment options and outcomes. The doctor will guide patient through the tool and explain the information to help them to make informed decisions.The decision aid tool contains concise information to compare the pros and cons of dialysis vs. transplant treatments, living donor vs. deceased donor transplant, accepting higher quality vs. lower quality deceased donor kidney offers, and increased infectious risk kidneys vs. standard infectious risk kidneys. We also created a calculator to estimate a patient’s likely outcomes on the kidney transplant wait list based on the transplant regions or center and the individual’s medical condition. Preliminary testing suggests that patients find the tool and the likely outcomes helpful in leading to informative decision making.
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He, Xiaoming, Shawn Mcgee, James E. Coad, Paul A. Iaizzo, David J. Swanlund, Stan Kluge, Eric Rudie i John C. Bischof. "Investigation of the Thermal and Injury Behavior During Microwave Thermal Therapy of Porcine Kidney". W ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-32048.

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In this paper, we report on the characterization of microwave therapy of normal porcine kidneys both in vitro and in vivo. This technology is being developed for eventual use in the treatment of small renal cell carcinoma (RCC) by minimally invasive procedures. During experiments, microwave energy was applied through an interstitial microwave probe (Urologix, Plymouth, MN) to the kidney cortex with occasional involvement of the kidney medulla. The thermal histories at several locations were recorded. After treatment, the kidneys were bisected and small tissue slices were cut out at approximately the same depth as the thermal probes. The tissue slices were further processed for histological study. Both cellular injury and the area of microvascular stasis were quantitatively evaluated by histology. Absolute rate kinetic models of cellular injury and vascular stasis were developed and fit to this data. A 3-D finite element thermal model based on the Pennes Bioheat equation was developed and solved using a commercial software package (ANSYS, V5.7). The Specific Absorption Rate (SAR) of the microwave probe was measured experimentally in tissue equivalent gel-like solution. The thermal model was first validated by the measured in vitro thermal histories. It was then used to determine the blood perfusion term in vivo.
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Cornelio, Cristina, Lucrezia Furian, Antonio Nicolò i Francesca Rossi. "Using Deceased-Donor Kidneys to Initiate Chains of Living Donor Kidney Paired Donations". W AIES '19: AAAI/ACM Conference on AI, Ethics, and Society. New York, NY, USA: ACM, 2019. http://dx.doi.org/10.1145/3306618.3314276.

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Cargill, Robert S., Kevin K. Toosi i Edward J. Macarak. "Mechanical Properties of the Fetal Bovine Bladder Lamina Propria and Their Correlation With Changes in Extracellular Matrix". W ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-193131.

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The urinary bladder is an organ whose purpose is to store urine at low pressure and periodically expel it. This system normally operates at relatively low pressure to protect the kidneys from the deleterious effects of increased pressure. In certain pathologies, this organ can be subject to a decrease in compliance (“stiffening”) and an increase of the storage pressure which causes higher back pressure on the kidney and ultimately results in kidney damage if untreated. Clinically, these pathologies are exemplified in disorders such as myelomeningocele, posterior urethral valves, dysfunctional voiding, and disorders associated with spinal cord injuries. In these disorders, bladder structure is altered and the bladder becomes stiff and noncompliant.
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Gasimzade, G. Sh. "Diagnostics of the injuries of kidneys". W Scientific achievements of the third millennium. LJournal, 2019. http://dx.doi.org/10.18411/scienceconf-05-2019-21.

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Raporty organizacyjne na temat "Kidneys"

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Zhang, Mingzhu, Wujisiguleng Bao, Luying Sun, Zhi Yao i Xiyao Li. Efficacy and safety of finerenone in chronic kidney disease associated with type 2 diabetes: meta-analysis of randomized clinical trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, marzec 2022. http://dx.doi.org/10.37766/inplasy2022.3.0020.

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Review question / Objective: To assess the beneficial effect and safety of finerenone for patients with chronic kidney disease associated with type 2 diabetes. Condition being studied: Chronic kidney disease (CKD) is a major contributor to morbidity and mortality from non-communicable diseases, affecting almost 700 million people worldwide. Approximately 40% of patients with diabetes have CKD, which exposes them to a 3-fold higher risk of cardiovascular death versus those with T2D alone. Strategies to protect the kidneys of patients with CKD and T2D may reduce their risk of cardiovascular events. Finerenone, a nonsteroidal, selective mineralocorticoid receptor antagonist, reduced composite kidney and cardiovascular outcome in trials involving patients with chronic kidney disease. Recently, quite a few clinical studies have been conducted to compare finerenone and placebo. Our meta-analysis aimed to investigate the efficacy and safety of finerenone in chronic kidney disease associated with T2D. 1st author* - Mingzhu Zhang and Wujisiguleng Bao contributed equally to this study.
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Elias, Julio, Nicola Lacetera i Mario Macis. Paying for Kidneys? A Randomized Survey and Choice Experiment. Cambridge, MA: National Bureau of Economic Research, luty 2019. http://dx.doi.org/10.3386/w25581.

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Agarwal, Nikhil, Itai Ashlagi, Michael Rees, Paulo Somaini i Daniel Waldinger. Equilibrium Allocations under Alternative Waitlist Designs: Evidence from Deceased Donor Kidneys. Cambridge, MA: National Bureau of Economic Research, luty 2019. http://dx.doi.org/10.3386/w25607.

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Agarwal, Nikhil, Charles Hodgson i Paulo Somaini. Choices and Outcomes in Assignment Mechanisms: The Allocation of Deceased Donor Kidneys. Cambridge, MA: National Bureau of Economic Research, listopad 2020. http://dx.doi.org/10.3386/w28064.

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Hua, Zi Bo, i Lv Yuan Chen. Human UCB MSC versus placebo for effect on kidney fibrosis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, październik 2022. http://dx.doi.org/10.37766/inplasy2022.10.0104.

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Review question / Objective: Human UCB MSC versus placebo for effect on kidney fibrosis Condition being studied: Renal fibrosis is the final outcome of long-term chronic kidney disease, and the kidney will lose its basic function. This experiment will explore the effect of Human UCB MSC for effect on kidney fibrosis. Main outcome(s): Correlation analysis of Human UCB MSC treatment on renalfibrosis.
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Roth, Alvin, Tayfun Sonmez i M. Utku Unver. Kidney Exchange. Cambridge, MA: National Bureau of Economic Research, wrzesień 2003. http://dx.doi.org/10.3386/w10002.

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Roth, Alvin, Tayfun Sonmez i M. Utku Unver. Pairwise Kidney Exchange. Cambridge, MA: National Bureau of Economic Research, sierpień 2004. http://dx.doi.org/10.3386/w10698.

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Morani, Ajaykumar, Ahmad Mubarak i Raghunandan Vikram. Imaging and kidney cancer. BJUI Knowledge, maj 2019. http://dx.doi.org/10.18591/bjuik.0097.

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Agarwal, Nikhil, Itai Ashlagi, Eduardo Azevedo, Clayton Featherstone i Ömer Karaduman. Market Failure in Kidney Exchange. Cambridge, MA: National Bureau of Economic Research, czerwiec 2018. http://dx.doi.org/10.3386/w24775.

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Wilkie, Martin. Kidney Services: Improving at Scale. Redaktor Helen Crisp. Renal Association, 2020. http://dx.doi.org/10.37900/hfqireport.

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