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1
McRae, Vicki. "Output, input and interaction in formal/informal teacher interactions and in NS, NNS children's interactions". Thesis, University of British Columbia, 1987. http://hdl.handle.net/2429/26884.
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Output, input and interaction are examined in this study for a native English speaking (NS) teacher and for native and non-native English speaking (NS, NNS) young children in two situations in the classroom, child organized and teacher organized. Video tapes and transcripts of fourteen samples of interactions in teacher organized situations and fourteen samples of naturally occurring interactions in child organized situations, each limited to the first consecutive one hundred utterances, were analyzed. Output was assessed in terms of verbal participation - utterances and words. Input and interaction were assessed both for discourse features (twelve negotiating devices) and in terms of the situational structure of the contexts that existed during the interactions - their distance from the speaker and the action was assessed with measures of exophoric and anaphoric reference (twenty-four reference items).
The results indicate: 1) that output or verbal participation varies for the teacher and the NS, NNS children with situation, 2) that discourse features, often used to assess input, vary in their use by the teacher and the children with the situational context, increase with verbal participation, and may not be useful measures of input, and 3) that the situational structure of the contexts that exist during teacher organized interactions and child organized interactions vary with situation - the distance of the language and the action from the speaker as well as the nature of the interaction. Individual variations amongst items, within and across groups are noted.
It is concluded that: 1) output, input and interaction vary with situation, 2) data analyses concerning input and interaction are more meaningful if they are related to the output occurring in different situations, and 3) L2 researchers will benefit from moving beyond the analysis of discourse features as the sole predictors of input during interaction to examine other aspects of the interaction situation.Education, Faculty of
Graduate
2
Liang, Qiyu Ph D. Massachusetts Institute of Technology. "Strongly interacting photons via Rydberg-Rydberg interactions". Thesis, Massachusetts Institute of Technology, 2017. http://hdl.handle.net/1721.1/115027.
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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Physics, 2017.Cataloged from PDF version of thesis.
Includes bibliographical references (pages 181-188).
A quantum nonlinear optical medium, i.e. a medium where the light propagation depends on photon number, has been a long-standing goal due to its applications in quantum information, communication and metrology. When the medium is nonlinear at single photon level, it can be viewed as strong interactions between individual photons mediated by the medium. Here, we achieve such strong interactions by coupling the photons to highly polarizable Rydberg states with a phenomena called electromagnetically induced transparency (EIT). The strong van der Waals or dipole-dipole interactions between Rydberg excitations map to the photons under EIT conditions. The photons are incident on a cigar-shaped laser-cooled rubidium cloud in free space. After the photons emerge out of the cloud, we measure the photon correlations from time-resolved single photon detections, which reveal crucial information about the quantum states of strongly interacting two or three photons. In this thesis, I will present four experiments. The first two experiments demonstrate quantum nonlinearities with a propagating continuous wave (cw) light field via Rydberg-Rydberg interactions in the dissipative and dispersive regimes, respectively. In the dissipative regime, strong photon anti-bunching is observed. In the dispersive regime, we achieve a conditional phase shift ~ [pi]/4, together with photon-bunching driven by attractive force. Moreover, the photons acquire a finite mass and we see evidence for a diphoton molecule. In the third experiment, by measuring higher-order correlation functions, we observe a three-photon bound state evidenced by tighter binding in addition to a larger conditional phase shift than the two-photon states. By comparing with an effective field theory, our results suggest that there might be a three-photon force on top of the pairwise interactions owing to the saturation of the interaction. Namely, only one Rydberg excitation can be created within a characteristic length scale called blockade radius. Finally, we explore the exchange interaction instead of the widely studied blockade shifts. Under the exchange interactions, a propagating photon and a stored one experience coherent collisions protected by a symmetry of the Hamiltonian and pick up a robust [pi]/2 phase shift.
by Qiyu Liang.
Ph. D.
3
El, Jed Mehdi. "Interactions sociales en univers virtuel : Modèles pour une interaction située". Phd thesis, Université Paul Sabatier - Toulouse III, 2006. http://tel.archives-ouvertes.fr/tel-00144856.
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La recherche proposée s'intéresse au développement d'un modèle d'interaction sociale capable de prendre en compte, en univers virtuel collaboratif, une partie de la dimension émotionnelle et sociale des interactions humaines.Dans notre approche, chaque utilisateur contrôle son propre avatar (représentation de l'utilisateur dans l'environnement virtuel) et peut prendre des décisions selon ses propres perceptions, son expertise et historique. La problématique de recherche devient donc d'offrir une solution pour maintenir un contexte d'interaction 'riche' lors de la collaboration.
Nous proposons des solutions qui permettent d'enrichir l'interaction sociale en univers virtuel. D'une part, l'interface proposée permet aux interactants d'exploiter leurs références indexicales (par exemple pointer de la main des objets de l'univers, orienter le regard vers une direction, etc.). D'autre part, notre modèle d'interaction sociale permet de produire automatiquement des comportements chez les avatars qui soient pertinents par rapport au contexte de l'interaction (par exemple distribuer le regard vers ses interlocuteurs, regarder les autres avatars en marchant, effectuer des expressions gestuelles en parlant, etc.).
Nous proposons également un modèle émotionnel pour simuler les états internes des personnages virtuels en interaction.
Ces modèles s'intègrent dans une architecture multi-agents capable de fusionner de façon 'réaliste' les actions intentionnelles décidées par l'acteur humain et les comportements non-intentionnels (produits par le modèle d'interaction sociale) comme les gestes, postures, expressions émotionnelles qui dépendent du contexte dans lequel évoluent les avatars.
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Kan, Viirj. "Molecular design interactions : material synthesis for human interaction with fluids". Thesis, Massachusetts Institute of Technology, 2017. http://hdl.handle.net/1721.1/112539.
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Thesis: S.M., Massachusetts Institute of Technology, School of Architecture and Planning, Program in Media Arts and Sciences, 2017.Cataloged from PDF version of thesis.
Includes bibliographical references (pages 89-99).
[Color illustrations] Figure 0-1. Key elements within a Molecular Design Interactions interaction loop. Be it information embodied within rain, the oceans, a dinner plate, or human tears; the flow of information through fluids provides insights into the biological and chemical states of systems. Yet a large portion of our everyday experience with these systems remain inaccessible to users, designers and engineers whom operate outside the context of chemical disciplines. This thesis introduces a design framework coined Molecular Design Interactions, along with a toolbox of material based input-output devices termed Organic Primitives to facilitate the design of interactions with organic, fluid-based systems. The design methodology utilizes organic compounds from food for the development of color, odor and shape changing information displays. Activated by units of fluid information called droplets, this thesis focuses on pH signals in fluid as a model to demonstrate how molecular scale phenomena can be brought from materials into applications for interaction with a range of organic systems. A design language and vocabulary, drawing from signaling theory and molecular associations, offer designers a method with which to translate sensor-display output into meaningful experience designs for human perception. The design space showcases techniques for how the Organic Primitives can transcend beyond mere input-output devices to achieve higher order complexity. Passive and computational methods are presented to enable designers to control material interface output behaviors. An evaluation of the individual output properties of the sensors-actuators is presented to assess the rate, range, and reversibility of the changes as a function of pH 2-10. Strategies for how the materiality of objects can be augmented using Organic Primitives are investigated through several applications under four contexts: environmental, on-body, food, and interspecies. Molecular Design Interactions offers a process and toolbox to create interfaces between humans and molecules in fluids, across scales, from the nano to the macro systems.
by Viirj Kan.
S.M.
5
Oiknine, Michel. "Interactions médicamenteuses de la théophylline". Paris 5, 1988. http://www.theses.fr/1988PA05P144.
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Bimbard, Erwan. "Production and interaction of photons using atomic polaritons and Rydberg interactions". Thesis, Palaiseau, Institut d'optique théorique et appliquée, 2014. http://www.theses.fr/2014IOTA0015/document.
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Produire et faire interagir entre eux des photons optiques de façon contrôlée sont deux conditions nécessaires au développement de communications quantiques à longue distance, et plus généralement au traitement quantique d’information codée sur des photons. Cette thèse présente une étude expérimentale de solutions possibles a ces deux problèmes, en utilisant la conversion des photons en excitations collectives (polaritons) dans un nuage d’atomes froids, placé dans le mode d’une cavité optique de faible finesse (~100). Dans un premier temps, des polaritons entre états atomiques fondamentaux sont utilisés pour « mettre en mémoire » une excitation unique dans le nuage. Celle-ci est ensuite convertie efficacement en un photon unique, dont le champ est analysé par tomographie homodyne. La fonction de Wigner de l’état à un photon est reconstruite a partir des données expérimentales, et présente des valeurs négatives, démontrant que les degrés de liberté de ce photon (mode spatio-temporel et état quantique) sont complètement contrôlés. Dans un second temps, les photons sont couplés à des polaritons impliquant des états de Rydberg. Les fortes interactions dipolaires entre ces derniers se traduisent par des non-linéarités optiques dispersives très importantes, qui sont caractérisées dans un régime d’excitation classique. Ces non-linéarités peuvent être amplifiées jusqu’à ce qu’un seul photon suffise à modifier totalement la réponse du système, permettant en principe de générer des interactions effectives entre photonsControllably producing optical photons and making them interact are two key requirements for the development of long-distance quantum communications, and more generally for photonic quantum information processing. This thesis presents experimental studies on possible solutions to these two problems, using the conversion of the photons into collective excitations (polaritons) in a cold atomic cloud, inside the mode of a low-finesse optical cavity (~100). Firstly, ground-state polaritons are used to store a single excitation in the cloud memory. This polariton is then efficiently converted into a single photon, whose field is characterized via homodyne tomography. The single photon state’s Wigner function is reconstructed from the experimental data and exhibits negative values, demonstrating that the photon’s degrees of freedom (spatio-temporal mode and quantum state) are well controlled. Secondly, photons can be coupled to polaritons involving Rydberg states. The strong dipolar interactions between these give rise to very strong optical dispersive nonlinearities, that are characterized in a classical excitation regime. These nonlinearities can be amplified until a single photon is enough to modify the entire system’s response, allowing in principle for the generation of effective photon-photon interactions
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Carrillo, Sonia. "Father-child interaction and its relation to children's interactions with peers /". Digital version accessible at:, 1999. http://wwwlib.umi.com/cr/utexas/main.
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Wicks, P. J. "Plume interactions". Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239265.
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Pascoe, Dominic James. "Orbital interactions". Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/33196.
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It is widely accepted that the sharing of electrons constitutes a bond. Conversely, molecular interactions that do not involve electron transfer, such as van der Waals forces and electrostatics are defined as "non-bonding" or "non-covalent" interactions. More recently computational and experimental observations have shown situations where the division between "bonding" and "non-bonding" interactions is blurred. One such class of interactions are known as σ-hole interactions. Chapter 1 provides a literature review of investigations into the nature of σ-hole interactions, highlighting the individual contributing factors. Chapter 2 provides a detailed analysis into the nature of chalcogen-bonding interactions. Synthetic molecular balances are employed for experimental measurements of conformational free energies in different solvents, facilitating a detailed examination of the energetics and associated solvent and substituent effects on chalcogen-bonding interactions. The chalcogen-bonding interactions examined were found to have surprisingly little solvent dependence. The independence of the conformational free energies on solvent polarity, polarisability and H-bond characteristics showed that electrostatic, solvophobic or dispersion forces were not dominant factors in accounting for the experimentally observed trends. A molecular orbital analysis provided a quantitative relationship between the experimental free energies and the molecular orbital energies, which was consistent with chalcogen-bonding interactions being dominated by an n→σ* orbital delocalisation. Chapters 3 and 4 both use the molecular orbital modelling approach established in Chapter 2 to investigate the potential partial covalency in H-bonding and carbonyl···carbonyl interactions. H-bonding is generally considered to be an electrostatically dominated interaction. However, computational results have suggested a partial covalent character in H-bonding. The molecular orbital analysis revealed an n→σ* electron delocalisation in all H-bonding systems evaluated. However, no quantitative correlation could be found with experimental free energies. Similarly, the nature of carbonyl···carbonyl interactions has been subject to debate, with electrostatic or an n→π* electron delocalisation having been proposed as the dominant factors. The molecular orbital analysis employed here showed that n→π* delocalisation was exceptionally geometry dependent. Studies of literature systems reveal that n→π* delocalisation contributes to overall stability of a range of systems, with a quantitative link between molecular orbital energy and conformational free energies.
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Rego, Kristen. "Altered Interactions". VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/2160.
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Surrounding materials, signage, and detritus on the daily path offer plenty to look at, if not too much. The eye seeks comfort in its passive vision by ignoring its peripheries. Identification of my personal vision reveals itself through the manipulation of ignored material. I consider hand-made vs. machine made, singular vs. the multiple particularly in plastics, packaging and other utilitarian objects. Industrial processes influence my one-person operation. Understanding the way objects are made allows for an opportunity to connect with them. I’m already surrounded by them, the least I can do is get to know them better.
11
Erlandsson, Fredrik. "Human Interactions on Online Social Media : Collecting and Analyzing Social Interaction Networks". Doctoral thesis, Blekinge Tekniska Högskola, Institutionen för datalogi och datorsystemteknik, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-15503.
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Online social media, such as Facebook, Twitter, and LinkedIn, provides users with services that enable them to interact both globally and instantly. The nature of social media interactions follows a constantly growing pattern that requires selection mechanisms to find and analyze interesting data. These interactions on social media can then be modeled into interaction networks, which enable network-based and graph-based methods to model and understand users’ behaviors on social media. These methods could also benefit the field of complex networks in terms of finding initial seeds in the information cascade model. This thesis aims to investigate how to efficiently collect user-generated content and interactions from online social media sites. A novel method for data collection that is using an exploratory research, which includes prototyping, is presented, as part of the research results in this thesis. Analysis of social data requires data that covers all the interactions in a given domain, which has shown to be difficult to handle in previous work. An additional contribution from the research conducted is that a novel method of crawling that extracts all social interactions from Facebook is presented. Over the period of the last few years, we have collected 280 million posts from public pages on Facebook using this crawling method. The collected posts include 35 billion likes and 5 billion comments from 700 million users. The data collection is the largest research dataset of social interactions on Facebook, enabling further and more accurate research in the area of social network analysis. With the extracted data, it is possible to illustrate interactions between different users that do not necessarily have to be connected. Methods using the same data to identify and cluster different opinions in online communities have also been developed and evaluated. Furthermore, a proposed method is used and validated for finding appropriate seeds for information cascade analyses, and identification of influential users. Based upon the conducted research, it appears that the data mining approach, association rule learning, can be used successfully in identifying influential users with high accuracy. In addition, the same method can also be used for identifying seeds in an information cascade setting, with no significant difference than other network-based methods. Finally, privacy-related consequences of posting online is an important area for users to consider. Therefore, mitigating privacy risks contributes to a secure environment and methods to protect user privacy are presented.
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Yao, Jerry Wei-Hua. "IDK : an Interaction Development Kit to design interactions for lightweight autonomous vehicles". Thesis, Massachusetts Institute of Technology, 2019. https://hdl.handle.net/1721.1/127725.
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Thesis: S.M., Massachusetts Institute of Technology, School of Architecture and Planning, Program in Media Arts and Sciences, 2019Cataloged from PDF of thesis.
Includes bibliographical references (pages 78-80).
Various studies have demonstrated that privately owned cars will become significantly less prevalent in the city in the next 10 to 15 years. Other efficient alternatives for mobility platforms within the city are in demand around the world. One example is the emergence of the PEV (Persuasive Electric Vehicle), an agile autonomous bike-sharing platform (M Lin, 2015). Based on this trend, it is reasonable to anticipate that increasingly more mobility systems of different forms will emerge in urban areas in the future. These new mobility systems might not necessarily be similar to cars; they may instead be a new class of social robot that could blend into the city more seamlessly. Moreover, when there is no longer a driver within each vehicle, designing human-machine interface (HMI) that is simple for users to process will be more important than ever.
For example, if a pedestrian encounters a lightweight autonomous vehicle for which it is apparent that no one is in the vehicle, how can the pedestrian understand the intention of the vehicle? And how can we, as designers, make this more intuitive and seamless? This thesis presents IDK, which is an Interaction Development Kit equipped with essential tools to help facilitate the design and prototyping process. IDK could be physically installed in PEVs, thereby enabling designers and developers to prototype human-machine interactions in a rapid and intuitive manner. This thesis also identifies multiple situations that a lightweight autonomous vehicle may encounter while navigating through streets and proposes a range of interactions that can tackle these problems. All prototypes from this thesis are based on the latest version of the PEV as an interactive platform.
The proposed interactions are evaluated through outdoor testing as well as indoor exhibitions to determine how people respond to these new norms of communication. My hope is that the results of this thesis will provide useful insights for designers and developers who seek to develop interactions that allow humans to seamlessly interact with lightweight autonomous vehicles.
by Jerry Wei-Hua Yao.
S.M.
S.M. Massachusetts Institute of Technology, School of Architecture and Planning, Program in Media Arts and Sciences
13
Yang, Lixu. "Non-covalent interactions in solution". Thesis, University of Edinburgh, 2013. http://hdl.handle.net/1842/8097.
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Non-covalent interactions taking place in solution are essential in chemical and biological systems. The solvent environment plays an important role in determining the geometry and stability of interactions. This thesis examines aromatic stacking interactions, alkyl-alkyl interactions, edge-to-face aromatic interactions, halogen bonds and hydrogen…hydrogen interactions in solution. Chapter 1 briefly introduces the different classes of non-covalent interactions, in addition to the state-of-the-art models and methods for investigating these weak interactions. The chapter finishes with a focus on dispersion interaction in alkanes and arenes. Chapter 2 investigates dispersion interactions between stacked aromatics in solution using a new class of complexes and thermodynamic double mutant cycles (DMCs). In extended aromatics, dispersion was detected as providing a small but significant contribution to the overall stacking free energies. Chapter 3 concerns the experimental measurement of alkyl-alkyl dispersion interactions in a wide range of solvents using Wilcox torsion balances. The contribution of dispersion interactions to alkyl-alkyl association was shown to be very small, with DMC, QSPR method and Hunter's solvation model. Chapter 4 studies edge-to-face aromatic interactions in series of solvents. In the open system, edge-to-face aromatic interactions were found to be sensitive to the solvent environment. The solvent effects were complicated and cannot be rationalised by a single parameter. Further analysis is needed. Chapter 5 describes a preliminary approach to investigate organic halogen…π interactions in solution using supramolecular complexes and torsion balances. Chapter 6 is a preliminary investigation of the ability of hydrogen atoms to act as H bond acceptors in silane compounds. Computations and 1H NMR demonstrated a weak interaction between silane and perfluoro-tert-butanol.
14
Nam, Hye In. "Multiplexed fragmentation and protein interaction reporter technology application to human cells". Pullman, Wash. : Washington State University, 2009. http://www.dissertations.wsu.edu/Thesis/Summer2009/h_nam_071509.pdf.
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Thesis (M.S. in Chemistry)--Washington State University, August 2009.Title from PDF title page (viewed on Sept. 21, 2009). "Department of Chemistry." Includes bibliographical references (p. 60-66).
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Wheadon, Andrew John. "Wave-turbulence interaction in shallow water numerical models : asymptotic limits, and subgrid interactions". Thesis, University of Exeter, 2018. http://hdl.handle.net/10871/34333.
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The ability to directly simulate all atmospheric motion is currently well beyond the limits of the computers available to us. As such techniques must be developed that accurately model important processes in an affordable manner. Large-scale balanced motion is well understood, but as affordable resolution increases, models are able to resolve scales where large-scale turbulence and small-scale waves are important. This requires a new set of techniques that respect the interactions between these different kinds of motion. In this thesis we look at two ways of assessing the accuracy of models capable of representing the scales at which these interactions occur. The first approach uses asymptotic limit solutions to derive a set of terms whose scale is known. These terms can then be evaluated as the model approaches a relevant asymptotic regime, and a `good' model should reproduce the expected rate of scaling. We apply this method of asymptotic limit solutions to an Eulerian and a Lagrangian shallow water model. The former is based upon ENDGame, the model currently in use at the Met Office, and the latter is based upon a candidate model from GungHo which is seeking a replacement for ENDGame. In addition, the Eulerian model is evaluated with both small and large timesteps and the results confirm the ability of the semi-implicit scheme to retain accuracy at large timesteps. Errors in the higher-order diagnostics used in this section highlight the need to make these analytic diagnostics consistent with the discretisations of the model in question. The second method involves looking at the exchanges of energy in a spectral shallow water model in order to inform the design of subgrid models. By running a high-resolution simulation and truncating the energy at a certain wavenumber, comparing the result to a run without truncation shows the contribution of the scales below the truncation limit. We extend this by separating the total energy into separate components that may be truncated and evaluated individually in order to give a more complete picture of energy exchanges at the subgrid scale.
16
Xue, Vincent. "Modeling and designing Bc1-2 family protein interactions using high-throughput interaction data". Thesis, Massachusetts Institute of Technology, 2018. http://hdl.handle.net/1721.1/120446.
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Thesis: Ph. D., Massachusetts Institute of Technology, Computational and Systems Biology Program, 2018.Cataloged from PDF version of thesis.
Includes bibliographical references (pages 153-164).
Protein-protein interactions (PPIs) play a major role in cellular function, mediating signal processing and regulating enzymatic activity. Understanding how proteins interact is essential for predicting new binding partners and engineering new functions. Mutational analysis is one way to study the determinants of protein interaction. Traditionally, the biophysical study of protein interactions has been limited by the number of mutants that could be made and analyzed, but advances in high-throughput sequencing have enabled rapid assessment of thousands of variants. The Keating lab has developed an experimental protocol that can rank peptides based on their binding affinity for a designated receptor. This technique, called SORTCERY, takes advantage of cell sorting and deep-sequencing technologies to provide more binding data at a higher resolution than has previously been achievable. New computational methods are needed to process and analyze the high-throughput datasets. In this thesis, I show how experimental data from SORTCERY experiments can be processed, modeled, and used to design novel peptides with select specificity characteristics. I describe the computational pipeline that I developed to curate the data and regression models that I constructed from the data to relate protein sequence to binding. I applied models trained on experimental data sets to study the peptide-binding specificity landscape of the Bc1-xL, Mc1-1, and Bf1-1 anti-apoptotic proteins, and I designed novel peptides that selectively bind tightly to only one of these receptors, or to a pre-specified combination of receptors. My thesis illustrates how data-driven models combined with high-throughput binding assays provide new opportunities for rational design.
by Vincent Xue.
Ph. D.
17
Gil, Pascual Miriam. "Adapting Interaction Obtrusiveness: Making Ubiquitous Interactions Less Obnoxious. A Model Driven Engineering approach". Doctoral thesis, Universitat Politècnica de València, 2013. http://hdl.handle.net/10251/31660.
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La Computaci'on Ubicua plantea proveer de inteligencia a nuestros entornos ofreciendo servicios a los usuarios que permitan ayudarlos en su
vida cotidiana. Con la inclusi'on de dispositivos ubicuos en nuestra vida
(por ejemplo los dispositivos m'oviles), los usuarios hemos pasado a estar siempre conectados al entorno, pudiendo interactuar con el. Sin embargo, a diferencia de las interacciones de escritorio tradicionales donde
los usuarios eran quienes ped'¿an informaci'on o introduc'¿an datos, las
interacciones ubicuas tienen que lidiar con un entorno de los usuarios
variable, demandando uno de los recursos mas valiosos para los usuarios: la atenci'on humana. De esta forma, un reto en el paradigma de
computaci'on ubicua es regular las peticiones de atenci'on del usuario.
Esto implica que las interacciones de los servicios deber'¿an comportarse
de una manera ¿considerada¿ teniendo en cuenta el grado en que cada
servicio se inmiscuye en la mente del usuario (el nivel de molestia).
Partiendo de las bases de la Ingenier'¿a Dirigida por Modelos (MDE)
y de los principios de la Computaci'on Considerada, esta tesis se orienta a dise¿nar y desarrollar servicios que sean capaces de adaptar sus
interacciones de acuerdo a la atenci'on del usuario en cada momento. El
principal objetivo de esta tesis es introducir capacidades de adaptaci'on
considerada en los servicios ubicuos para proporcionar interacciones que
no perturben al usuario. Esto lo conseguimos mediante un proceso de desarrollo que cubre desde el dise¿no de los servicios hasta su implementaci'on, centr'andose en los requisitos de adaptaci'on de la interacci'on
particulares para cada usuario.
Para el dise¿no del comportamiento de la interacci'on en base al nivel
de molestia se han de¿nido unos modelos de intromisi'on e interacci'on
independientes de la tecnolog'¿a. Estos modelos son los que posteriormente conducen la adaptaci'on de la interacci'on din'amicamente, por
medio de una infraestructura aut'onoma que los usa en tiempo de ejecuci'on. Esta infraestructura es capaz de detectar cambios en la situaci'on
del usuario (por ejemplo cambios en su localizaci'on, su actividad, etc.)
y planear y ejecutar modi¿caciones en la interacci'on de los servicios.
Cuando se detecta un cambio del contexto del usuario, los servicios se
auto-adaptan para usar los componentes de interacci'on m'as apropiados
de acuerdo a la nueva situaci'on y no molestar al usuario.
Adem'as, como las necesidades y preferencias de los usuarios pueden
cambiar con el tiempo, nuestra aproximaci'on utiliza la estrategia del
aprendizaje por refuerzo para ajustar los modelos de dise¿no iniciales de
forma que maximicemos la experiencia del usuario. El dise¿no inicial
de la interacci'on basado en el nivel de molestia nos asegura un comportamiento inicial consistente con las necesidades de los usuarios en
ese momento. Luego, este dise¿no se va re¿nando de acuerdo al comportamiento y preferencias de cada usuario por medio de su retroalimentaci'on a trav'es de la experiencia de uso. Adem'as, tambi'en proporcionamos una interfaz m'ovil que permite a los usuarios ¿nales personalizarse de forma manual los modelos en base a sus propias preferencias.
El trabajo presentado en esta tesis se ha llevado a la pr'actica para su
evaluaci'on desde el punto de vista de los dise¿nadores y de los usuarios
¿nales. Por una parte, el m'etodo de dise¿no se ha validado para comprobar que ayuda a los dise¿nadores a especi¿car este tipo de servicios. Pese
a que el proceso de desarrollo no ofrece una automatizaci'on completa,
las gu'¿as ofrecidas y la formalizaci'on de los conceptos implicados ha demostrado ser 'util a la hora de desarrollar servicios cuya interacci'on es
no molesta. Por otra parte, la adaptaci'on de la interacci'on en base al
nivel de molestia se ha puesto en pr'actica con usuarios para evaluar su
satisfacci'on con el sistema y su experiencia de usuario. Esta validaci'on ha desvelado la importancia de considerar los aspectos de molestia en
el proceso de adaptaci'on de la interacci'on para ayudar a mejorar la
experiencia de usuario.In Ubiquitous Computing environments, people are surrounded by a lot of embedded services. Since ubiquitous devices, such as mobile phones, have become a key part of our everyday life, they enable users to be always connected to the environment and interact with it. However, unlike traditional desktop interactions where users are used to request for information or input data, ubiquitous interactions have to face with variable user¿s environment, making demands on one of the most valuable resources of users: human attention. A challenge in the Ubiquitous Computing paradigm is regulating the request for user¿s attention. That is, service interactions should behave in a considerate manner by taking into account the degree in which each service intrudes the user¿s mind (i.e., the obtrusiveness degree). In order to prevent service behavior from becoming overwhelming, this work, based on Model Driven Engineering foundations and the Considerate Computing principles, is devoted to design and develop services that adapt their interactions according to user¿s attention. The main goal of the present thesis is to introduce considerate adaptation capabilities in ubiquitous services to provide non-disturbing interactions. We achieve this by means of a systematic method that covers from the services¿ design to their implementation and later adaptation of interaction at runtime
Gil Pascual, M. (2013). Adapting Interaction Obtrusiveness: Making Ubiquitous Interactions Less Obnoxious. A Model Driven Engineering approach [Tesis doctoral no publicada]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/31660
TESIS
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Ralph, Alan. "The verbal interaction analysis system: A valid measure of competence in interpersonal interactions". Thesis, Ralph, Alan (1988) The verbal interaction analysis system: A valid measure of competence in interpersonal interactions. PhD thesis, Murdoch University, 1988. https://researchrepository.murdoch.edu.au/id/eprint/50427/.
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This thesis proposes a novel approach to the assessment of persons experiencing difficulties with interpersonal interactions. Conversation skills were selected as the focus of the research, these being an important element in such interactions. A broad review of psychological research associated with 4 different perspectives on this topic indicated a variety of approaches to defining, assessing and remediating problems Social, developmental, with interpersonal interactions. educational and clinical perspectives were explored. Clinically useful measurement procedures either evaluated the global effect of persons or evaluated specific structural components of their behaviour. The former provided little information about how to intervene to bring about improvements, while the latter failed to identify behaviour which consistently correlated with other indicators of competent performance. Valid measures from other domains were examined for their application to the assessment of conversation skills.
An initial study analysed data from a sample of university students and job seekers to provide a benchmark for subsequent comparison with a newly developed measurement system. Results were interpreted to support previous research findings that component analysis measures were not appropriate. Sequential and interaction analysis concepts were adapted to develop the Verbal Interaction Analysis System. The VIAS measured the effect of verbal behaviour in interpersonal interactions by focusing on whether the topic of conversation was maintained and if contributions were made which developed the current topic. The VIAS was applied to a number of different dyadic interactions beginning with a reanalysis of the initial study. Scores obtained with this measure resulted in improved correlations with global judgements of competence and predicted high- and low- competent subjects. Subsequent experiments supported the validity of the VIAS. The VIAS was administered to a group of low-competent subjects during a social-skills training programme and was used in a clinical case study with a person experiencing difficulties with interpersonal interactions. In addition, experiments were carried out with university students to investigate the effects on the VIAS of manipulating the behaviour of the confederate or the subject during initial interactions. Results indicated that the VIAS (1) was easy to use with high inter-rater agreement. (2) was sensitive to improvements in the competence of one category of low-competent subjects during a social skills training programme, (3) assisted in the selection of target IV behaviour in a single-subject clinical intervention, and (4) was sensitive to manipulations of behaviour such as changing levels of responsibility for maintaining the interaction. The major advantage of the System was its flexibility. Empirically determined adjustments to the scoring procedure produced valid scores from a different type of interaction, as exemplified by a job interview.
The potential of the System as a research tool is discussed firstly, in the context of determining the demands made in different interpersonal interactions and secondly, for its relevance as an aid to improving maintenance and transfer (generalisation) of treatment gains.
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Threadgill, James. "Unsteadiness of shock wave boundary layer interactions across multiple interaction configurations and strengths". Thesis, Imperial College London, 2016. http://hdl.handle.net/10044/1/48475.
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Shock Wave Boundary Layer Interactions (SWBLIs) represent complex flow phenomena that remain poorly understood despite their prevalence on high-speed vehicles, in part due to their complicated underlying physics. In particular, the mechanisms that drive the high-amplitude, low-frequency unsteadiness within the interaction have perplexed researchers for many years while remaining a limitation to vehicle performance and a potential danger to airframe integrity. This investigation has specifically examined the influence of interaction strength and configuration type on the characteristic unsteady behaviour that describes the flow environment. Until now, researchers have typically focused on testing a specific configuration in a given test facility. This approach can obscure meaningful conclusions that may be drawn due to the interference of the test environment. The present research effort therefore tackles this flaw by assessing flow behaviours across a range of SWBLIs, all tested within a common environment. Four strengths of oblique shock reflection interactions and two strengths of compression ramp interactions have been assessed and compared. Experiments have been conducted in the Imperial College Supersonic Wind Tunnel with a Mach 2 turbulent incoming boundary layer with momentum thickness Reynolds number of 8000. Using a combined approach of synchronised PIV and fast-response wall-pressure measurements the unsteady elements to the interactions have been investigated. The spectral evolutions of unsteady wall-pressure disturbances are assessed throughout each of the interactions. Results confirm that the high-frequency component of the separation shock spectral content is common across all interactions. Meanwhile, low-frequency amplitudes scale with the interaction length, acting to decrease the characteristic frequency used to describe such motion when the interaction strength is increased. Instantaneous shock structures have also been identified which confirm the presence of two unsteady mechanisms governing the dynamics of the separation shock: rotation and translation. Quasi-steady modelling of these mechanisms indicates how their relative dominance varies with interaction strength and configuration type. This body of work represents a unique assessment of valuable data that is crucial to the development of unsteady SWBLI understanding.
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Senouf, David Benjamin. "Interactions statines - clopidogrel /". Genève : [s.n.], 2005. http://www.unige.ch/cyberdocuments/theses2005/SenoufD/these.pdf.
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Valstar, Ank. "Protein-surfactant interactions". Doctoral thesis, Uppsala University, Department of Physical Chemistry, 2000. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1070.
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Protein-surfactant interactions in aqueous media have been investigated. The globular proteins lysozyme and bovine serum albumin (BSA) served as model proteins. Several ionic and non-ionic surfactants were used.
Fluorescence probe measurements showed that at low sodium dodecyl sulfate (SDS) concentration (< 0.1 M) one micelle-like SDS cluster is bound to lysozyme. From dynamic light scattering (DLS) results it was observed that lysozyme in the complex does not correspond to the fully unfolded protein. At high SDS concentration (> 0.1 M) one compact and one more extended lysozyme-SDS complex coexist.
The influence of surfactant alkyl chain length and headgroup on BSA-surfactant complex formation was investigated. In these studies, binding isotherms were determined by nuclear magnetic resonance (NMR), DLS was used to measure the hydrodynamic radii of the complexes and the size of the micelle-like aggregates on BSA was determined using fluorescence probe methods.
It was observed from fluorescence measurements that the number of bound SDS molecules does not depend on the presence of the disulfide bridges. Reduced proteins wrap more efficiently around the micelle-like structures, resulting in somewhat smaller complexes, as observed with DLS.
Concentrated BSA-SDS solutions and the corresponding heat-set gels were investigated using DLS and fluorescence probe methods. Correlation lengths in the gel were determined and it was concluded that SDS forms micelle-like aggregates on BSA in concentrated solution and gel phase. The gel region in the ternary phase diagram BSA-SDS-3.1 mM NaN3 has been determined at room temperature.
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Nguyen, Hai. "Acanthamoeba-Campylobacter Interactions". Thèse, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/20172.
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Campylobacter jejuni is an avian commensal bacterium and causes gastrointestinal diarrhea in humans called campylobacteriosis. Campylobacteriosis is acquired by consumption of undercooked poultry contamined with C. jejuni. Poultry can become colonized from contaminated drinking water. The chicken flock and drinking water of 4 poultry farms in Ontario were sampled and the prevalence of C. jejuni in these flocks was determined to be 16.7% over a 1 year sampling period. We determined that contamined- water was a significant risk factor for Campylobacter-positive flocks from flaA typing, PFGE analysis, and genomotyping several isolated strains. Free living amoebae, such as Acanthamoeba species, live in the drinking water of poultry farms. It is hypothesized that Acanthamoeba in the drinking water of poultry farms can take up and act as environmental reservoirs of C. jejuni. Acanthamoeba species were isolated from the drinking water. Acanthamoeba strains were found to act as a vehicle for protection, persistence and growth of C. jejuni isolated from the farm water. The transcriptome of both C. jejuni and A. castellanii during the initial stages of C. jejuni internalization were described by RNA-seq. C. jejuni oxidative defence genes (such as katA, sodB, fdxA) and some other unknown genes (Cj0170, Cj1325, Cj1725) were found to be essential in the interaction with A. castellanii. Our findings suggest that Acanthamoebae act as a C. jejuni reservoir and could be a contributing source of C. jejuni in the environment. Through transcriptomics studies, we have begun to uncover some genetic clues involved in this interaction.
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Echevarría, García Joaquín, i Barrantes James José Ordinola. "Proyecto ensemble interactions". Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2016. http://hdl.handle.net/10757/622175.
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En la actualidad, no existe gran variedad de herramientas que permitan a la comunidad de desarrolladores Android implementar aplicaciones orientadas a entornos de múltiples pantallas y que, adicionalmente, les permitan cumplir con lo descrito por Ensemble Interactions y los patrones de diseño definidos para estos entornos, los cuales, en conjunto, son conceptos que proponen el trabajo en conjunto de todos los dispositivos disponibles en un mismo entorno. Por otro lado, de las pocas herramientas que permiten el desarrollo de este tipo de aplicaciones, algunas han sido implementadas por grandes empresas desarrolladoras de dispositivos móviles que limitan sus herramientas para que funcionen únicamente con los dispositivos que le pertenecen.
Por todo ello, este trabajo busca implementar una herramienta que permita a la comunidad de desarrolladores Android desarrollar aplicaciones móviles orientadas a entornos de múltiples dispositivos y que se alineen a lo definido por Ensemble Interactions y los patrones de diseño. Dicha herramienta basará la interacción entre los dispositivos sobre una red Wi-Fi sin la necesidad que esta cuente con acceso a internet. Asimismo, esta herramienta estará disponible en dos versiones, una para el desarrollo de aplicaciones Android y otra para el desarrollo de aplicaciones en Samsung Smart TVs.
A continuación, en el primer capítulo se expondrá el proyecto y su gestión. Luego, se dará paso al marco teórico sobre el que se basa este trabajo. En el tercer capítulo se analizará a detalle la situación actual de todas herramientas y tecnologías que permiten desarrollar aplicaciones orientadas a entornos de múltiples pantallas. A continuación, en el quinto capítulo describirá la metodología de trabajo empleada en el desarrollo de este proyecto y los resultados obtenidos. En el sexto capítulo se presentará el producto final del trabajo y las medidas de gestión tomadas a lo largo de su desarrollo. Finalmente, se listarán las conclusiones y recomendaciones propuestas con este trabajo.
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Todd, Allan. "Helium-Antihydrogen Interactions". Thesis, University of Nottingham, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485533.
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Alza, Guzmán Diego Andrés, i Martinez Jean Carlo Canales. "Ensemble interactions iOS". Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2018. http://hdl.handle.net/10757/622927.
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Definir e implementar un SDK que integre las principales características definidas por Ensemble Interactions (EI). Para ello, se analizarán e implementarán los patrones descritos por E.I. De esta forma, la investigación brindará el marco teórico necesario para el correcto entendimiento de EI y los seis patrones principales que lo definen.
La interpretación de los resultados obtenidos en el análisis de los patrones será fundamental debido a que esta será la base que respaldara los artefactos que se realizaran a lo largo del proyecto. Asimismo, la implementación se dividirá en entregables: Desarrollar un SDK que permita la conectividad entre los dispositivos mediante WiFi y Bluetooth, así como implementar dos pruebas de concepto que implementen los patrones descritos por EI, por último, desarrollar una aplicación final que integre las características principales de Ensemble Interactions.
Con respecto a los riesgos presentes en el desarrollo del proyecto, se ha remarcado el hecho que, actualmente, no existe una aplicación que integre todos los conceptos descritos por EI en los dispositivos Apple, por lo cual plantear el desarrollo de una aplicación que lo haga es un reto significativo. Asimismo, un riesgo fundamental del proyecto es la correcta interpretación de los patrones y su implementación.Nowadays, there are not many tools that allow IOS developer community implement applications oriented to multi-display environments and, additionally, to fulfill what is described by Ensemble Interactions and the design patterns defined for these environments, which are concepts that propose the joint work of all available devices in the same environment. On the other hand, of the few tools that allow the development of such applications, some have been implemented by large companies that also develop mobile devices and limit their tools to work with only those devices from their own. Therefore, this paper seeks to implement a tool that allows IOS developer communitydevelop mobile applications for multiple devices environments that meet what is described by Ensemble Interactions and design patterns. This tool base the interaction between devices on a Wi-Fi network without access to the internet and Bluetooth. Then, in the first chapter the project and its management will be discussed. Then, the theoretical framework on which this work is based. The third chapter will analyze in detail the current status of all tools and technologies that allow the development of multi-display environments applications. Then, the fifth chapter will describe the methodology employed in the development of this project and the results obtained. In the sixth chapter, the final product of labor and management measures taken during its development will be presented. Finally, conclusions and recommendations proposed in this work are listed.
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Bartzoka, Vasiliki. "Silicone-protein interactions". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape3/PQDD_0035/NQ66252.pdf.
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Schef, Peter. "Weak Atomic Interactions". Doctoral thesis, Stockholm : Physics Department, Stockholm University, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-1064.
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Bredenberg, Johan. "Modelling biomolecular interactions /". Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-571-9.
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Murray, Philip. "Interactions & answers /". Online version of thesis, 1989. http://hdl.handle.net/1850/11539.
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Schroers, Bernd Johannes. "Quantised soliton interactions". Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260578.
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Marsh, Adam. "Oocyte-follicle interactions". Thesis, University of Nottingham, 2012. http://eprints.nottingham.ac.uk/12684/.
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The ovarian follicle is an individual functional unit that provides the optimal environment for the oocyte within to develop. This thesis outlines the research in the field of ovarian follicular dynamics that has already been established, and further develops these findings to explore in greater detail the relationship between the oocyte and its environment, both in an in vitro and in vivo setting, using a variety of species. The first major research area involved studying the role of oocyte-secreted factors, which was examined using a series of dose response experiments. These were performed using an ovine granulosa cell culture model, and elucidated a possible role for a collaborative action of BMP15 and GDF9 in the promotion of oestradiol synthesis, while inhibiting production of progesterone in this species. This finding was then further investigated using an ovine in vivo immune-neutralisation study, the endocrine and histological results of which confirmed these findings in a proportion of these animals, although this study was limited by the animals appearing to have been in seasonal anoestrus. The second major topic that was investigated was based around the ovarian microenvironment, in terms of angiogenesis and hypoxia. Again, ovine granulosa cell cultures were used, in this instance to examine the effect of hypoxic conditions on steroid hormone production. These experiments indicated that somatic cell steroid hormone production is likely to be compromised by a hypoxic environment, and therefore that the provision of oxygen through a local blood supply may be a vital requirement for these cells. To investigate the relevance of studying ovarian blood supply and physiology in a clinical setting, perfusion studies were carried out based on a series of bovine phantom experiments, which were used to study the effect of varying flow rate on the parameters routinely measured using this technology. The routine clinical ultrasonographic methods of ovarian assessment such as 4D ViewTM, SonoAVCTM and VOCAL were also examined, based on bovine phantom experiments, revealing possible weaknesses in the data provided by ultrasound that are increasingly relied upon in the clinical setting. Finally, a clinical trial was carried out to try and encompass all of the findings of the in vitro and in vivo work, in order to place these theories into context in a human IVF setting. This work was unfortunately limited severely by a lack of patient numbers, but some interesting results were observed with regard to oocyte developmental potential relationships with follicular fluid and somatic cell factors, as well as ultrasound measures of peri-follicular blood supply.
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McQuillan, Jonathan. "Bacterial-nanoparticle interactions". Thesis, University of Exeter, 2010. http://hdl.handle.net/10036/3101.
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Bionanotechnology is an intersection between biology and nanotechnology, a field in which novel applications for very small materials are being realised at an alarming rate. Nanoparticles have 3 dimensions that can be measured in nanometers, their small size conferring upon them different properties from individual atoms or the bulk material. The interactions between these unique materials and microorganisms are often toxic, thus have been exploited for antimicrobial applications. However, there is a considerable paucity of data for the underlying molecular mechanisms. This study has been carried out to investigate the interactions that occur between nanoparticles and bacteria with the objective of identifying these toxicological mechanisms and novel nanoparticle effects, using the model Gram negative organism Escherichia coli K12. This study has identified metal nanoparticles that are a superior vehicle for the delivery of toxic metal ions to E. coli. The nanoparticles associate with the bacterial surface, but do not cross the cell wall. They then dissolve, releasing a concentration of metal ions that accumulate at the bacterial-nanoparticle interface, enhancing the antibacterial efficacy compared to the concentration of metal ions in the bulk solution phase. Measurement of the whole transcriptome response to silver nanoparticles in comparison to the silver ion indicates that the different modes of ion delivery may induce a differential stress response. Moreover, this data identifies molecular mechanisms that are involved in the toxicity of this metal that is now becoming increasingly prevalent in society. The dissolution based toxic effects of zinc oxide nanoparticles are augmented by an interaction with ultra-violet light, offering an alternative mode for nanoparticle toxicity.
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Wade, R. C. "Ligand-macromolecule interactions". Thesis, University of Oxford, 1988. http://ora.ox.ac.uk/objects/uuid:576ce119-6a93-4eb0-a7e4-1f2513736dbd.
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The optimisation of ligand-macromolecule interactions is fundamental to the design of therapeutic agents. The GRID method is a procedure for determining energetically favourable ligand binding sites on molecules of known structure using an empirical energy potential. In this thesis, it has been extended, tested, and then applied to the design of anti-influenza agents. In the GRID method, the energy of a hydrogen-bond is determined by a function which is dependent on the length of the hydrogen-bond, its orientation at the hydrogen-bond donor and acceptor atoms, and the chemical nature of these atoms. This function has been formulated in order to reproduce experimental observations of hydrogen-bond geometries. The reorientation of hydrogen atoms and lone-pair orbitals on the formation of hydrogen-bonds is calculated analytically. The experimentally observed water structures of crystals of four biological molecules have been used as model systems for testing the GRID method. It has been shown that the location of well-ordered waters can be predicted accurately. The ability of the GRID method to assist in the assignment of water sites during crystallographic refinement has been demonstrated. It has also been shown that waters in the active site of an enzyme may be both stabilized and displaced by a bound substrate. Ligands have been designed to block the highly conserved host cell receptor site of the influenza virus haemagglutinin in order to prevent the attachment of the virus to the host cells. The protein was mapped energetically by program GRID and specific ligand binding sites were identified. Ligands, which exploited these binding sites, were then designed using computer graphics and energy minimization techniques. Some of the designed ligands were peptides and these were synthesised and assayed. Preliminary results indicate that they may possess anti-influenza activity.
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Peberdy, Jemma C. "Biomacromolecule-ligand interactions". Thesis, University of Warwick, 2004. http://wrap.warwick.ac.uk/4069/.
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The interactions and binding of various ligands to biomacromoleculcs e.g. DNA and proteins finds widespread application in the design and development of novel pharmaceuticals. DNA has been identified as the target molecule for a number of drugs and carcinogens and the supramolecular synthetic approach has led to the discovery of a range of bimetallo iron cylinders that bind to DNA inducing remarkable structural effects. The cylinders arc chiral and the enantiomers were separated on cellulose packed in paper or in a column. The optimum mobile phase for efficient separation was found to be 90% acctonitrilc: 10% 0.02 M NaCl. The (M)-enantiomers of the parent cylinder have been found to bind to DNA in the major groove. I Hydrophobic methyl groups were added at various positions on the ligand backbone. UV/visible absorbance, circular and linear dichroism were used to investigate any interactions of the metal complex with DNA with the aim of investigating any sequence preference or selectivity upon binding. Competitive binding studies and molecular dynamics simulations were used to probe the binding geometries of the enantiomers of the parent cylinder and two methylated cylinders to DNA as the exact site of interaction of the (P)-enantiomers of the parent cylinder was unclear. It was concluded that the methylated bimetallo iron cylinders bind to DNA and provide major groove recognition and may show some sequence preference. Circular dichroism was used to structurally characterise a range of buanosine-rich oligonucleotides (GRO's) and to investigate their interactions with a nucleolar protein - nucicolin. Biological/anti-proliferative activity has been related to the ability of the oligonucleotide to bind to this protein. It was found that nucleolin does bind to a biologically active GRO in the presence of K+ and induces a structural change in it.
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Kant, Avinash. "Starch-aroma interactions". Thesis, University of Nottingham, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.403302.
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Chamberlain, Charles William. "Hydrogen-antihydrogen interactions". Thesis, University of Nottingham, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.395602.
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Xie, Kang. "Spatial soliton interactions". Thesis, University of Salford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.358454.
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Parkinson, Andrew. "DNA-amine interactions". Thesis, University of Warwick, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302652.
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Arnold, Rebecca. "Earthworm - copper interactions". Thesis, University of Reading, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430943.
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Kingham, Paul. "Microglial-neuronal interactions". Thesis, University College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.394396.
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Boeg, Martin. "Endogenous social interactions". Thesis, University College London (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430058.
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Jones, Susan. "Protein-protein interactions". Thesis, University College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338952.
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Augustus, Adebayo Samuel. "Attractive steric interactions". Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391708.
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Rice, Judith. "Bone biomaterial interactions". Thesis, University of Liverpool, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366672.
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Rooney, E. K. "Drug-membrane interactions". Thesis, University of Southampton, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375371.
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Patel, Ramila. "Transposase-IR interactions". Thesis, University of Bristol, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240011.
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Zheng, Qingshu. "Understanding metallophilic interactions". Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/33237.
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Metallophilic (metal-metal) interactions are weak interactions between closed-shell (d10, s2) or pseudo-closed-shell (d8) metal cations. This type of interaction is generally believed to be responsible for various intriguing structures, luminescence, catalysis and magnetism. To gain a better understanding of metallophilic interactions, both experimental and computational investigations have been carried out in this thesis. Chapter 1 gave an up-to-date literature review on the definition, significance, and methods of estimating metallophilic interactions. The disputed nature and strength of metallophilic interactions encouraged us to further understand them. Chapter 2 focused on aurophilic interactions between AuI cations. Aurophilic interactions were observed in the solid state, but not well expressed in solution. Further experimental and computational results suggested that the strength of aurophilic interactions were weaker than electrostatic interactions. The nature of aurophilic interactions arose from orbital interactions rather than dispersion. Chapter 3 presented the study of metallophilic interactions between group 10 metal centres, including PtII-PtII, PdII-PdII and NiII-NiII. A series of cyclometalated square-planar metal complexes with different metals or substituents were prepared. PtII-PtII interactions were found to be stronger than PdII-PdII and NiII-NiII interactions. The dimerization constants of the Pt-containing complexes increased in line with increasing electron-withdrawing ability. Chapter 4 investigated the solvent-induced and thermally dependent colour changes of the Pt-containing complexes synthesised in chapter 3. Metallophilic interactions were proposed to be important in influencing the luminescence properties.
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Swanson, Eric (Eric Peter). "Interactions with context". Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/37356.
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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Linguistics and Philosophy, 2006.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Includes bibliographical references (p. [109]-119).
My dissertation asks how we affect conversational context and how it affects us when we participate in any conversation -- including philosophical conversations. Chapter 1 argues that speakers make pragmatic presuppositions when they use proper names. I appeal to these presuppositions in giving a treatment of Frege's puzzle that is consistent with the claim that coreferential proper names have the same semantic value. I outline an explanation of the way presupposition carrying expressions in general behave in belief ascriptions, and suggest that substitutivity failure is a special case of this behavior. Chapter 2 develops a compositional probabilistic semantics for the language of subjective uncertainty, including epistemic adjectives scoped under quantifiers. I argue that we should distinguish sharply between the effects that epistemically hedged statements have on conversational context, and the effects that they have on belief states. I also suggest that epistemically hedged statements are a kind of doxastic advice, and explain how this hypothesis illuminates some otherwise puzzling phenomena. Chapter 3 argues that ordinary causal talk is deeply sensitive to conversational context. The principle that I formulate to characterize that context sensitivity explains at least some of the oddness of 'systematic causal overdetermination,' and explains why some putative overgenerated causes are never felicitously counted, in conversation, as causes. But the principle also makes metaphysical theorizing about causation rather indirectly constrained by ordinary language judgments.
by Eric Swanson.
Ph.D.
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Nigmatullina, Yuliya. "Visual-vestibular interactions". Thesis, Imperial College London, 2014. http://hdl.handle.net/10044/1/25086.
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Following repeated exposure to vestibular stimulation, the vestibular response as measured by the vestibular-ocular reflex and perception of self-motion is reduced. Similarly, prolonged viewing of a visual motion stimulus results in a reduced sensitivity to the adapting motion stimulus. These phenomena of visual-vestibular desensitisation are utilised as part of treatment of patients with peripheral or central vestibular disorders. Patients typically receive vestibular rehabilitation therapy, which involves exposure to repeated visual and/or vestibular stimulation. Whilst the effects of vestibular rehabilitation at the behavioural level have been widely studied, the neural mechanism of how it works is unclear. In this thesis, asymptomatic subjects were recruited to investigate the neural mechanisms underlying visual and vestibular desensitisation. In the first study, the effect of long term vestibular training was investigated on the vestibular psychophysical measures and on the structure of the brain. To this aim, a group of high level dancers and a group of non-dancers were recruited with both groups undergoing a battery of vestibular tests and neuroimaging brain scans. Compared to controls, dancers showed a significant reduction in both vestibular ocularmotor response and perception of self-motion. Moreover, in controls a significant correlation was found between ocularmotor and perceptual measures, which was absent in dancers. This uncoupling of the vestibular measures was also seen at the neuroanatomical level in the locus of the vestibular-cerebellum, as revealed by voxel based morphometry (VBM) analysis of the dancers' brain grey matter. Using diffusion tensor imaging (DTI), a widespread cortical white matter (WM) network was found to correlate with vestibular perception in the control group only. The findings suggest that in dancers, a cerebellar gating of perceptual signals to cortical regions takes place that may mediate the training-related resistance to vertigo. The second study of the thesis looked at the effect of a single prolonged exposure to unilateral visual motion stimulus in healthy untrained subjects. This involved using transcranial magnetic stimulation (TMS) induced phosphenes to assess early visual cortical excitability. Following visual motion adaptation, excitability of visual cortex (V1) was significantly reduced when viewing motion in the adapted direction and significantly increased when viewing motion in the non-adapted direction. This suggests that reciprocal inhibition takes place between oppositely tuned directionally selective neurones in V1 to facilitate motion perception. The visual cortical excitability returned to its prior-adaptation state after five minutes suggesting that a single exposure to visual motion stimulus is not sufficient to cause a long-term adaptive effect. The final study of the thesis investigated potential neural mechanisms involved in suppressing visual symptom of oscillopsia (perception of the world oscillating/moving), a potentially distressing condition that occurs in some vestibular and ocularmotor disorders. The study recruited participants with nystagmus and they were divided into two groups according to their experience of oscillopsia: symptomatic (with oscillopsia) and asymptomatic (no oscillopsia). TMS induced phosphenes were used to assess (1) whether visual cortical spatial updating takes place according to the eye position and (2) whether modulation of visual cortical excitability takes place during nystagmus. In the asymptomatic group only, evidence for both visual cortical updating and modulation of visual cortical excitability was found, which was absent in the symptomatic group. The findings suggest that spatial updating of eye position and changes in visual cortical excitability are implicated in the suppression of oscillopsia. In particular, the work presented in the thesis provides neuroanatomical imaging basis for vestibular adaptation and provides evidence for a direct cortical involvement in visual motion adaptation. Both of these mechanisms are likely to be involved in the clinical recovery process of patients with vestibular and ocularmotor disorders. Greater understanding of the neural mechanisms involved in long lasting visual-vestibular desensitisation will bring us closer to developing personalised treatments that are more effective in improving symptoms of patients with visuo-vestibular disorders.
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Padilla, Mélanie. "Des interactions carcérales". Nice, 2011. http://www.theses.fr/2011NICE2024.
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