Rozprawy doktorskie na temat „Inhibition”
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Booker, Samuel A. "Inhibiting inhibition : interactions amongst interneurons of the hippocampus". Thesis, University of Glasgow, 2011. http://theses.gla.ac.uk/2995/.
Pełny tekst źródłaGlossop, Paul. "Thrombin inhibition". Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244533.
Pełny tekst źródłaBonardi, C. "Discriminative inhibition". Thesis, University of Cambridge, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384313.
Pełny tekst źródłaBrian, Jessica Ann. "Inhibition in autism evidence of excessive inhibition-of-return /". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ56219.pdf.
Pełny tekst źródłaHeduy, Fabrice. "Inhibition cognitive et schizophrénie : étude en situation d'auto-inhibition". Lille 3, 2001. http://www.theses.fr/2001LIL30010.
Pełny tekst źródłaRoweth, Harvey George. "Mechanisms of platelet inhibition by the selective serotonin reuptake inhibitor citalopram". Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/275477.
Pełny tekst źródłaBowditch, William Antony. "Response inhibition and associative learning : training stimulus specific response inhibition". Thesis, University of Exeter, 2016. http://hdl.handle.net/10871/24923.
Pełny tekst źródłaChowdhury, Nahian Shahmat. "Intracortical Inhibition and Response Inhibition in healthy adults and gamblers". Thesis, The University of Sydney, 2019. https://hdl.handle.net/2123/21945.
Pełny tekst źródłaFrings, Christian. "Inhibition von Distraktorinformation". Kassel : Kassel Univ. Press, 2004. http://deposit.d-nb.de/cgi-bin/dokserv?idn=97180110X.
Pełny tekst źródłaSmith, Gary Thomas. "Inhibition of IPNS". Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.276831.
Pełny tekst źródłaElfant, David J. "Inhibiting inhibition : GABAergic networks in the CA1 area of the rat hippocampus". Thesis, University of Oxford, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.496867.
Pełny tekst źródłaShkirskiy, Viacheslav. "Corrosion inhibition of galvanized steel by LDH - inhibitor hybrids : Mechanisms of Inhibitor Release and Corrosion Reactions". Thesis, Paris 6, 2015. http://www.theses.fr/2015PA066216/document.
Pełny tekst źródłaThe current work was dedicated to the investigation of the fundamental mechanisms of the action of a layered double hydroxide (LDH) inhibitor hybrid coated systems for the corrosion protection of galvanized steel. The objective of the work was achieved by the realization of three milestones: (1) the identification of the effective water soluble inhibitor on Zn and steel substrates and the understanding the mechanisms of its action, (2) the revealing the factors and mechanisms controlling the release of the selected inhibitor from Zn2Al/-LDH hosts and (3) the understanding the mechanisms of coated system controlled by inhibitor release and its action. MoO42- showed the best inhibition efficiency comparable to CrO42- in alkaline and neutral solutions. The protective properties of MoO42- were assigned to the fast formation of Mo(V) film. The effect of MoO42- on the dissolution of low carbon steel was also verified to exclude the possible accelerating effect of chosen species. The leaching tests showed that MoO42- release from LDH was controlled by the nature of the exchanged ions from the media by ion-exchange mechanism at neutral pH and by the dissolution of the LDH framework at alkaline pH. The presence of only Cl- resulted in less than 40 % of MoO42- release after 24 hours of the immersion while the additions of the carbonates resulted in 100 % release after 1 hour. The immersion tests showed slight inhibiting effect of coated system in Cl and high in CO32- medias coherent with higher level of MoO¬42- released. The ways to control the inhibitor release and hence, the inhibition performance of coated systems were discussed in the vein of environment composition
Mizon, Guy Andrew. "Selective attention and inhibition : effects of inhibition tasks on subsequent distractor rejection". Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.404990.
Pełny tekst źródłaBearss, Nicole R. "Inhibition of Prostate Cancer via Inhibition of Peptidylglycine α-Amidating Monooxygenase (PAM)". University of Toledo / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1302200866.
Pełny tekst źródłaKöhncke, Clemens [Verfasser]. "Zerebrale Oxygenierungsänderungen bei Inhibition in einem Modell der transkallosalen Inhibition / Clemens Köhncke". Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2010. http://d-nb.info/1024743128/34.
Pełny tekst źródłaMcCready, Tara Lyn. "Inhibition of protein phosphatase-1 by endogenous inhibitor proteins and natural product toxins". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0032/NQ46885.pdf.
Pełny tekst źródłaGuerrant, William. "Targeted histone deacetylase inhibition". Diss., Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/44907.
Pełny tekst źródłaCamp, Gino. "Forgetting: inhibition or interference?" Rotterdam : Rotterdam : Erasmus Universiteit ; Erasmus University [Host], 2006. http://hdl.handle.net/1765/8200.
Pełny tekst źródłaCarter, Wendy Jayne. "Legumain structure and inhibition". Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.615940.
Pełny tekst źródłaRichardson, J. "Corrosion inhibition with amides". Thesis, University of Nottingham, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381056.
Pełny tekst źródłaCorin, Karolina A. (Karolina Ann) 1981. "Inhibition of myofibroblast contraction". Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/32381.
Pełny tekst źródłaIncludes bibliographical references (p. 46-49).
Although current medical procedures cannot restore complete function of a transected nerve, inserting both of its ends in a tube helps it regenerate. The regenerate is inferior to the uninjured nerve: it has a smaller diameter and poorer electrical conduction. Layers of contractile cells known as myofibroblasts have been observed around regenerated nerve portions. An inverse relationship between the layer thickness and the quality of the regenerate has also been observed. These findings suggest that the cells are exerting contractile forces which prevent the regenerating nerve from fully developing. Inhibiting this contraction should thus improve the quality of nerve regeneration. Alpha smooth muscle actin ([alpha]-SMA) is a critical contractile protein. Its expression can be upregulated by the growth factor TGF-[beta]1, and blocked by the pharmacological agent PP2. To investigate whether blocking SMA expression alone can inhibit myofibroblast contraction, NR6 wild type fibroblasts were seeded into short cylindrical collagen-GAG matrices, and administered either media alone, media with TGF-[beta]1 (3ng/ml), or media with TGF-[beta]1 and PP2 (10 [mu]M). Non-seeded matrix samples were also prepared. The matrix diameters were measured every day for 12 days, after which the matrices were digested and the number of adhered cells were counted. The daily change in matrix diameter was calculated. The results showed that the cells contracted the matrices. TGF-[beta]1 increased cell contractility, while PP2 inhibited it..
(cont.) Normalizing the Day 12 diameter change measurements to cell number and the original matrix diameter showed that TGF-[beta] increased the strain generated by each cell ... relative to ... for untreated cells), and that PP2 counteracted this effect (...). Using the linear elastic constitutive relations, the average force exerted per cell was calculated for the untreated cells (...), TGF-[beta]1 stimulated cells (...), and TGF-[beta] + PP2 stimulated cells (...). The cell counts after Day 12 indicate that PP2 interferes with cell adhesion to the matrices. After 6 hours in culture, 21% of untreated cells, 25% percent of cells treated with TGF-[beta] 1, and 25% of cells treated with TGF-[beta]1 and PP2 had adhered. By Day 12, only 12% of the seeded untreated cells, 14% of cells treated with TGF-[beta] I, and 3.2% of cells treated with both TGF-[beta]1 and PP2 remained adhered. This study thus indicates that PP2 inhibits cellular contraction, possibly by preventing cell-substrate adhesion
by Karolina A. Corin.
S.M.
Roberts, Henrietta Whitley. "Rumination and cognitive inhibition". Thesis, University of Exeter, 2013. http://hdl.handle.net/10871/10281.
Pełny tekst źródłaBonetti, Kelly. "Inhibition studies of SIRT1". Thesis, Boston University, 2013. https://hdl.handle.net/2144/12057.
Pełny tekst źródłaSilent Information Regulator 2 (Sir2) of Saccharomyces cerevisiae is the progenitor of an ancient family of proteins known as sirtuins. Sirtuins act on substrates in various regulatory pathways critical to normal cell function. Human SIRT1 is the closest known homologue of yeast Sir2. This study focuses on the function of human SIRT1 and the influence of this protein on the host inflammatory response. To better understand the role of SIRT1 and its role in disease, a working clone that expresses the SIRT1 protein is necessary. In this study, the human SIRT1 gene was amplified from commercially available template DNA using the Polymerase Chain Reaction (PCR). The SIRT1 gene was ligated into pET28b(+), a bacterial expression vector that works in Escherichia coli. The SIRT1 gene is expressed under control of the T7 promoter, which is not recognized by the transcriptional machinery in E.coli. Protein expression does not occur until a source of T7 RNA polymerase is provided. Once obtained, the SIRT1-pET28b(+) plasmid was transferred into TOP10, a bacterial maintenance strain. Once established, the SIRT1-pET28b(+) construct is transformed into an expression host containing a chromosomal copy of the T7 RNA polymerase gene. Induced by the addition of Isopropylthio-β-Galactoside (IPTG), the expression cell diverts almost all of its resources to express the target SIRT1 gene. Overexpression of the SIRT1 protein allows for characterization of enzyme activity. Characterization of the mechanism where SIRT1 is inhibited by the native inhibitor nicotinamide (NAM) and the clinical antimycobacterial agent pyrazinamide (PZA) is needed. The focus of this thesis is elucidation of the mechanism of inhibition of SIRT1. PZA, a clinical agent used to treat tuberculosis (TB), has been shown to allosterically inhibit SIRT1. It is of particular interest to determine where PZA, a NAM derivative, binds SIRT1 and if this binding can be included in natural regulatory network mechanisms within the cell. At the heart of this study, are attempts to understand the complex binding interactions of both PZA and pyrazinoic acid (POA), the chemotherapeutically active metabolite of PZA, in the presence of NAM. Competition experiments with these agents may prove useful to determine if these molecules interact at the same site, if the molecules can be displaced competitively, or if certain residues within parts of the enzyme are essential for characteristic binding.
Rodkey, Elizabeth A. "INHIBITOR RESISTANCE MECHANISMS AND INHIBITOR DESIGN IN ¿¿-LACTAMASES". Case Western Reserve University School of Graduate Studies / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=case1354463033.
Pełny tekst źródłaLembo, Gaia. "Substrate targeting and inhibition of editing deaminases". Doctoral thesis, Università di Siena, 2021. http://hdl.handle.net/11365/1144295.
Pełny tekst źródłaVitaliti, Alessandra. "Inhibition of tumor induced angiogenesis /". [S.l.] : [s.n.], 1999. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=13409.
Pełny tekst źródłaBell, Theodore Anthony. "Individual differences in memory inhibition /". view abstract or download file of text, 2005. http://wwwlib.umi.com/cr/uoregon/fullcit?p3181082.
Pełny tekst źródłaTypescript. Includes vita and abstract. Includes bibliographical references (leaves 95-104). Also available for download via the World Wide Web; free to University of Oregon users.
Åkerfelt, Annika. "Visual-tactile stop signal inhibition". [S.l. : s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=972887520.
Pełny tekst źródłaCook, Joanna Clare. "Ageing and inhibition in memory". Thesis, University of Southampton, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288442.
Pełny tekst źródłaLarson, Susan Joyce. "External inhibition of ethanol tolerance". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/NQ30100.pdf.
Pełny tekst źródłaBartels-Tobin, Lori R. "Naming and inhibition in aphasia". [Tampa, Fla.] : University of South Florida, 2007. http://purl.fcla.edu/usf/dc/et/SFE0001959.
Pełny tekst źródłaAmmar, Ahmed A. "Intake inhibition by neuropeptide Y /". Stockholm : Karolinska institutet, 2005. http://diss.kib.ki.se/2005/91-7140-308-6/.
Pełny tekst źródłaStrauss, Sandra Jean. "Proteasome inhibition in lymphoid malignancy". Thesis, Queen Mary, University of London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.429409.
Pełny tekst źródłaDay, Jonathan Robert Stewart. "Therapeutic inhibition of thrombin signalling". Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.434321.
Pełny tekst źródłaKingsbury, Oliver William. "The inhibition of cysteine proteinases". Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360390.
Pełny tekst źródłaTrunkfeild, Amy Elizabeth. "Inhibition of Glycosyl Transferase MurG". Thesis, University of Warwick, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.487830.
Pełny tekst źródła孫耀君 i Yiu-kwan Edmond Suen. "Backward inhibition in pathological gamblers". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41712638.
Pełny tekst źródłaFrings, Christian [Verfasser]. "Inhibition von Distraktorinformation / Christian Frings". Kassel : Kassel Univ. Press, 2004. http://d-nb.info/97180110X/34.
Pełny tekst źródłaHicks, Jake Thomas. "Surfactant aspects of corrosion inhibition". Thesis, University of Hull, 2007. http://hydra.hull.ac.uk/resources/hull:6996.
Pełny tekst źródłaBullock, Anthony James. "Metabolic inhibition in the ureter". Thesis, University of Liverpool, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366420.
Pełny tekst źródłaReith, Alison. "Inhibition of fibrinolysis in pregnancy". Thesis, University of Aberdeen, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303338.
Pełny tekst źródłaO'Connell, James P. "Matrix metalloproteinase activation and inhibition". Thesis, Open University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338338.
Pełny tekst źródłaAxamawaty, Mohammed Taleb Hassan. "Inhibition and inactivation of hydrolases". Thesis, University of Bristol, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.481028.
Pełny tekst źródłaPollux, Petra. "Cognitive inhibition in Parkinson's disease". Thesis, University of Lincoln, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.263964.
Pełny tekst źródłaTorres, Molina Maria. "Corrosion inhibition : a spectroscopic study". Thesis, University of Manchester, 2017. https://www.research.manchester.ac.uk/portal/en/theses/corrosion-inhibition-a-spectroscopic-study(7279a328-ec12-4bd4-b7c0-7c3f118095f4).html.
Pełny tekst źródłaHanczakowski, Maciej. "Inhibition in long-term memory". Thesis, University of Hull, 2012. http://hydra.hull.ac.uk/resources/hull:6355.
Pełny tekst źródłaCranwell, Joanne. "Inhibition training using smartphone technology". Thesis, University of Nottingham, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.659213.
Pełny tekst źródłaCook, Erik C. "Calcineurin: From Activation to Inhibition". UKnowledge, 2016. http://uknowledge.uky.edu/biochem_etds/29.
Pełny tekst źródłaBillard, 1959 Jean-Marie. "Olive inférieure et inhibition cérébelleuse". Paris 6, 1986. http://www.theses.fr/1986PA066044.
Pełny tekst źródłaEdge, Colin Michael. "Theoretical studies of enzyme inhibition". Thesis, University of St Andrews, 1989. http://hdl.handle.net/10023/14388.
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