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Caldana, Cleber Gomes. "Infusion". Florianópolis, SC, 2003. http://repositorio.ufsc.br/xmlui/handle/123456789/85828.
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Este trabalho apresenta um estudo sobre métodos de engenharia reversa para Sistemas Legados. Sistemas Legados caracterizam-se por apresentarem elevado custo de manutenção devido a não utilização dos conceitos de engenharia de software e são mantidos por desenvolvedores que não participaram da sua concepção. A Engenharia Reversa surge como uma abordagem para melhorar a manutenção de Sistemas Legados através de estudos sobre o código fonte e a documentação existente, caso exista, revitalizando a documentação inerente as etapas de Análise e Projeto, recuperando assim o entendimento do sistema. Também é apresentado um estudo de caso baseado no método de Engenharia Reversa FUSION/RE. O desenvolvimento do estudo de caso é descrito através de documentações geradas e dos procedimentos aplicados durante a aplicação do método FUSION/RE na Engenharia Reversa. Como contribuições deste trabalho são apresentadas alterações nos procedimentos do método FUSION/RE e uma proposta de validação da documentação gerada durante o processo de Engenharia Reversa. This work represents a study about Reverse Engineering for Legacy Systems.Legacy Systems are caracterized by high cost of maintenance due to the nonutilization of software engineering concepts, and are kept updated by developers that do not participated of the conception of the System. The Reverse Engineering emerge as an approach to improve the maintenance of the Legacy Systems through studies over the source code and the documentation, case it exists, revitalizing the documentation to the phases of Analysis and Project, recovering this way the understanding of the system. It is also presented a case study based on the FUSION/RE Reverse Engineering method. The development of the case study is described throuhg documentation generated and the procedures applied during the application of the FUSION/RE method on the Reverse Engineering. The contributions of this work focus on the alterations to the procedures on the FUSION/RE method and to a proposal of validation of the documentation generated during the Reverse Engineering proccess.
Casas, Ormeño Camila Alexandra, Nuñez Carlos Eduardo Ortiz, Barboza Ximena Alexandra Prado, Dias Fiorella del Pilar Salazar i Barrantes Adriana Stefhany Sarmineto. "Proyecto SANI". Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/652293.
Pełny tekst źródłaThe present project of a 100% natural infusion based on jamaica leaf, dehydrated pinacapple and cinnamon, which helps women combat the annoying symptoms of menstruation, such as headache, cramps and anxiety. The base of our filter has anticoagulant, antioxidant and relaxation properties. In the present work it will be announced hoy the problem was identified and how we detected the solution, for whom and hoy to approach them. It was found that women have low productivity at work or in studies when they are their menstrual period. Finally, we validete our hypotheses through personal interviews and focus groups. In order to implement this project, an in-depth analysis of the industry was carried out, such as consumers, suppliers, amog others. Likewise, plans were made for the different areas: Strategic, Operations, Marketing, Human Resources, Social Responsability, Financial. These plans have the strategics that we will use for the viability of the company. We had an initial investment of S/. 83,451 in the first year, the net income of year 1 is –S/. 58,540, for the second year S/. 272,438 and finally in the year 3 S/. 238,315.
Trabajo de investigación
Hahn, Robert G. "Clinical pharmacology of infusion fluids". Linköpings universitet, Anestesiologi med intensivvård, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-91319.
Pełny tekst źródłaMcQuinn, Dylan Thomas. "Infusion urban and domestic transformation /". Thesis, Montana State University, 2009. http://etd.lib.montana.edu/etd/2009/mcquinn/McQuinnD0509.pdf.
Pełny tekst źródłaBrandley, Mark Wesley. "Void Modeling in Resin Infusion". BYU ScholarsArchive, 2015. https://scholarsarchive.byu.edu/etd/5460.
Pełny tekst źródłaSchmidt, Thorsten. "Infusion, Hüftkopfanbohrung oder Infusion nach Hüftkopfanbohrung in der Behandlung der atraumatischen Hüftkopfnekrose und des Knochenmarködemsyndroms". kostenfrei, 2009. http://www.opus-bayern.de/uni-regensburg/volltexte/2009/1233/.
Pełny tekst źródłaLipsett, Mark Andrew. "Pancreatic plasticity during chronic glucose infusion". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0024/MQ51396.pdf.
Pełny tekst źródłaMarsollier-Ferrer, Catherine. "L'amnio-infusion en salle de travail". Montpellier 1, 1997. http://www.theses.fr/1997MON11090.
Pełny tekst źródłaPrice, William Evan. "Kinetics and equilibria of tea infusion". Thesis, Imperial College London, 1985. http://hdl.handle.net/10044/1/8238.
Pełny tekst źródłaKleine, Astrid, i Emma Stibe. "DropIt : Ett alternativt sätt att ge infusion". Thesis, Halmstad University, School of Business and Engineering (SET), 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-5214.
Pełny tekst źródłaThibaudeau, Mikaël. "Towards a fully integrated resin infusion process". Thesis, University of Southampton, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274693.
Pełny tekst źródłaZhang, Siqi. "Functional polymer fibre spinning by infusion gyration". Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10052048/.
Pełny tekst źródłaCorreia, Nuno André Curado Mateus. "Analysis of the vacuum infusion moulding process". Thesis, University of Nottingham, 2004. http://eprints.nottingham.ac.uk/12762/.
Pełny tekst źródłaRoloff, Nils. "Kontrollierte klinische Studie über die Auswirkungen einer Infusion mit hypertoner Kochsalzlösung auf die Kreislaufsituation bei Kühen mit rechtsseitiger Labmagenverlagerung". Giessen : VVB Laufersweiler, 2007. http://geb.uni-giessen.de/geb/volltexte/2007/4836/index.html.
Pełny tekst źródłaMacaulay, Ewan. "Ischaemia-reperfusion during infrainguinal bypass for critical limb ischaemia and the effects of a nitric oxide donor". Thesis, University of Aberdeen, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301228.
Pełny tekst źródłaSouza, Sérgio dos Santos. "Efeitos da dexmedetomidina, por via epidural ou infusão contínua intravenosa, em gatas anestesiadas com propofol e isofluorano e submetidas a ovariossalpingohisterectomia". Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/10/10137/tde-06032007-151544/.
Pełny tekst źródłaThis study compared the effects of epidural or continuous intravenous infusion of dexmedetomidine in isoflurane-anesthetized cats undergoing ovariohysterectomy. Twenty-one cats (weight: 3.06±0.35 kg) were premedicated with dexmedetomidine (4 mcg.kg-1, IM). Fifteen minutes later, propofol was titrated to allow endotracheal intubation and anesthesia was maintained in spontaneously breathing cats with isoflurane in oxygen using a Mapleson D system. Cats were randomly allocated to receive either epidural lidocaine (1 mg.kg-1, G1, n=7) or epidural lidocaine (1 mg.kg-1) + dexmedetomidine (4 mcg.kg-1, G2, n=7) or epidural lidocaine (1 mg.kg-1) + continuous intravenous infusion of dexmedetomidine (0,25 mcg.kg-1. min-1, G3, n=7). The volume of either epidural injection was adjusted to 0.3 mL.kg-1 with saline. The individual controlling depth of anesthesia was blinded to the drug being administered epidurally and intravenouslly. Heart (HR) and respiratory (RR) rates, systolic arterial blood pressure (SAP) and rectal temperature (RT) were recorded before and after 15 minutes of premedication. During anesthesia, heart (HR) and respiratory (RR) rates, invasive arterial blood pressures, end-tidal CO2, end-tidal isoflurane (ISOe), RT and muscular relaxation were recorded at 15 minute intervals from 20 until 80 minutes. Arterial blood gases were measured at 20 and 80 min after induction. HR, RR, RT, analgesia score, and recovery quality and times were compared for 3 hours after end of anesthesia. Paired t test were performed to compare the premedication effects and arterial blood gases at differents intervals. ANOVA with Tukey post-test and Friedmann with Dunn post-test were performed to parametric and nonparametric values, respectively (P<0.05). Dexmedetomidine premedication decreased HR, RR, SAP and RT. The induction dose of propofol was 7.4±1.4 mg.kg-1. When compared to the G1, epidural dexmedetomidine significantly decreased HR from 20 to 65 minutes of anesthesia and 150 and 180 minutes after end of anesthesia, however, continuous intravenous infusion decreased HR all times during anesthesia and recovery time. When compared to G2, continuous intravenous infusion of dexmedetomidine decreased HR at 60 and 90 minutes during recovery. In the G1 mean±SD ISOe concentrations ranged form 0.86±0.28% to 1.91±0.63% from 20 to 80 min. At the same time interval, ISOe concentrations were significantly lower in the G2 (ISOe ranged from 0.70±0.12% to 0.97±0.20%) and G3 (ISOe ranged from 0.69±0.12% to 1.17±0.25%). PaCO2 was significantly greater in G3 than G1 at 20 minutes. The recovery times were significantly lower in the G1 except for extubation time when compared with G2. There were no significant differences among groups for the remaining variables. It was concluded that premedication with dexmedetomidine produced cardiorespiratory depression. Epidural administration and continuous intravenous infusion of dexmedetomidine significantly reduced inhalant requirements for maintaining anesthesia and produced a better anesthesia recovery although of longer duration. Dexmedetomidine administration may cause bradycardia, however reduced HR does not affect arterial blood pressure.
Tohnai, Iwai. "Chemotherapy using Intra-Arterial Infusion for Oral Cancer". Nagoya University School of Medicine, 2006. http://hdl.handle.net/2237/6962.
Pełny tekst źródłaFan, Xiu-Di. "Substantia nigra dopamine infusion, behavioral and biochemical correlates". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ32783.pdf.
Pełny tekst źródłaHoogma, Roeland Petrus Leonardus Maria. "Subcutaneous insulin infusion in type 1 diabetes mellitus". [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2006. http://dare.uva.nl/document/29301.
Pełny tekst źródłaGharavi, Hosein. "Infusion of information systems in the stockbroking sector". Connect to thesis, 2006. http://portal.ecu.edu.au/adt-public/adt-ECU2006.0016.html.
Pełny tekst źródłaShafik, I. M. "Effects of magnesium infusion on renal calcium excretion". Thesis, University of Manchester, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379137.
Pełny tekst źródłaHoagland, David Wayne. "Continuous Permeability Measurement During Unidirectional Vacuum Infusion Processing". BYU ScholarsArchive, 2017. https://scholarsarchive.byu.edu/etd/6457.
Pełny tekst źródłaMurphy, Robert S. "The design of safety-critical medical infusion devices". Thesis, University of South Wales, 2007. https://pure.southwales.ac.uk/en/studentthesis/the-design-of-safetycritical-medical-infusion-devices(1557c702-3087-43f9-a399-99a9ba65ae9b).html.
Pełny tekst źródłaThompson, Joseph E. "Compaction and Cure of Resin Film Infusion Prepregs". Thesis, Virginia Tech, 2004. http://hdl.handle.net/10919/36479.
Pełny tekst źródłaMaster of Science
Waschburger, Diane Jaqueline. "Parâmetros Cardiorrespiratórios e Hematológicos em Cães Anestesiados com Isofluorano e Tramadol, Pré-medicados com Clonidina". Universidade Federal do Pampa, 2014. http://dspace.unipampa.edu.br:8080/xmlui/handle/riu/185.
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Com o presente estudo, propôs-se avaliar os efeitos da clonidina como medicação pré-anestésica, sobre parâmetros cardiorrespiratórios e hematimétricos em cães anestesiados com isoflurano, associada à infusão contínua de tramadol. Para isso, foram utilizados 8 cães sem raça definida, adultos, hígidos, com peso médio de 15,3 ± 3,7 kg, oriundos do canil da Universidade Federal do Pampa mediante doação. Cada animal foi anestesiado em duas ocasiões, com intervalo mínimo de um mês. Os animais foram distribuídos em dois grupos aleatórios: grupo Clonidina (GCL; pré-medicados com clonidina, 5 μg/kg) e grupo Controle (GC; pré-medicados com solução salina). Passados 15 minutos da MPA, os animais foram induzidos à anestesia geral pela administração de propofol 8mg/kg e mantidos com isoflurano à 1 CAM. Após período de estabilização, foi realizada a aplicação do bolus de tramadol (2 mg/kg) seguido pela infusão contínua do mesmo (1,5 mg/kg/h). Foram mensurados temperatura (oC), frequência cardíaca (FC), frequência respiratória (f), eletrocardiografia, pressões arteriais sistólica, diastólica e média (PAS/PAD/PAM), pressão parcial de dióxido de carbono ao final da expiração (EtCO 2 ), saturação de oxigênio (SpO2), hemograma, leucograma, glicemia, e lactacemia, dose de indução, tempo de extubação e qualidade da recuperação anestésica. As mensurações foram realizadas nos seguintes períodos: antes da MPA, antes da indução, antes do bolus de tramadol e após início das infusões, a cada 10 minutos até se completarem 60 minutos das mesmas. Os parâmetros hematológicos, glicemia e lactacemia foram mensurados nas amostras de sangue coletadas antes da aplicação da medicação pré-anestésica, antes da indução, antes do bolus do tramadol e aos 30 e 60 minutos após início das infusões. A avaliação estatística dos resultados foi realizada utilizando-se teste de ANOVA seguido pelo teste de Tukey (p<0,05). Houve diferenças na frequência cardíaca e nas demais variáveis as diferenças não foram significativas ao longo do período experimental. A associação demonstrou-se segura em animais hígidos, sendo necessário mais estudos quanto à doses, vias de aplicação e antinocicepção na espécie.
With this study, the effects of premedication with clonidine over cardiorespiratory and hematimetry in dogs anesthetized with isoflurane and receiving continuous infusion of tramadol, were evaluated. Eight crossbreeding healthy adult dogs, weighting 15,3±3,7kg, provided from Federal University of Pampa kennel, were used. Animals were randomly anesthetized twice with a month interval and allocated in two groups (n=8), Clonidine (CLG) and Control (CG). Animals in CLG received a 5 μg kg -1 bolus of Clonidine diluted in 1mL as premed, while animals in CG received an injection of 1 mL of saline. Anesthesia was acquired with propofol 8 mg kg -1 and maintained with isoflurane (1MAC). After a stabilization period, animals received a bolus of tramadol (2 mg kg -1 ) followed by a continuous rate infusion of 1.5 mg kg -1 h of the same drug. Parameters evaluated were: body temperature (oC), heart rate (HR), respiratory frequency (f), electrocardiography, systolic, diastolic and median arterial blood pressure (SAP, DAP and MAP, respectively), end-tidal carbon dioxide (EtCO 2 ), hemoglobin saturation (SpO 2 ), hematimetric, leucocitary, glucose, lactate, propofol consumption, time of extubation and recovery quality. Data were collected before premed, before induction, before tramadol bolus, and each 10 minutes after CRI was initiated, until a 60 minutes period was achieved. Blood samples were performed before premed, before induction, before tramadol bolus and 30 and 60 minutes after CRI was initiated. Data were evaluated with ANOVA followed by Tukey`s test (p<0.05). It was observed a significant decrease in HR, while other variables showed no differences throughout the experimental period. It was concluded that the association has been shown to be safe for use in healthy animals. Further studies are necessary to determinate if this drug could enhance antinociceptive effect of tramadol in dogs.
Thuresson, Jenny, i Mathilda Davidsson. "Moneo: Säkert varningssystem för detektering vid infiltration". Thesis, Högskolan i Halmstad, Sektionen för ekonomi och teknik (SET), 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-15255.
Pełny tekst źródłaEach year more than 150 children suffer from severe injuries during IV infusion therapy in Sweden. In close cooperation with Hallands sjukhus Halmstad, a new warning system has been developed for detection of infiltration during IV infusion. For more than 30 years this kind of product has been requested from pediatrician and innovator Kent- Åke Henricson. Infiltration is a medical term used to describe when you infuse medical drugs into the surrounding tissue instead of into the vein. Depending on the type of medicine that has been infiltrated, the severity of the injury varies from light skin reaction to severe necrosis. A severe infiltration leads to extended hospital stays for the patient, which can be costly for the hospital. Today a nurse does regular checkups every two hours at the puncture site in order to insure that the medicine is being delivered properly. This is very time consuming for medical staff, as well as, annoying for the patient. Our product will function as an additional safe guard during infusion therapy and is adapted to be used with existing infusion devices. Moneo allows for easier monitoring by medical staff while giving children a more safe treatment. Children are active patients and Moneo’s light weight and smart design allows for physical movement and comfort of the patient. It is also easily integrated into the existing procedures and routines of the medical professionals. The project group is proud and happy to present their final thesis, Moneo, which has resulted in a product that can eliminate unnecessary suffering in the children receiving IV infusion therapy thereby providing a more safe treatment option. It is a basic medical principle that no patient should suffer negative side effects of a medical procedure. Moneo can be used to avoid these kinds of concerns.
Ackerman, Henrieta. "Improving thinking abilities by creating a culture of a thinking classroom during science and technology lessons for pupils of the 11-12 years old age group". Thesis, Anglia Ruskin University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248883.
Pełny tekst źródłaChanner, Kevin John. "Experimental investigation into the double RIFT diaphragm forming process". Thesis, University of Warwick, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.246819.
Pełny tekst źródłaKenerson, Jonathan E. "Quality Assurance and Quality Control Methods for Resin Infusion". Fogler Library, University of Maine, 2010. http://www.library.umaine.edu/theses/pdf/KenersonJE2010.pdf.
Pełny tekst źródłaMallen, Cheryl Ann. "Rethinking pedagogy for the times: a change infusion pedagogy". University of Southern Queensland, Faculty of Education, 2006. http://eprints.usq.edu.au/archive/00004789/.
Pełny tekst źródłaDuQuesnay, Renée. "Infusion of oligonucleotides into the brain produces behavioral effects". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ36433.pdf.
Pełny tekst źródłaSjöstrand, Fredrik. "Volume kinetics of glucose solutions given by intravenous infusion /". Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-235-7/.
Pełny tekst źródłaAvison, Shane J. "Supercritical infusion of flavour into synthetic- and bio- polymers". Thesis, University of Nottingham, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250532.
Pełny tekst źródłaGoran, M. I. "Metabolic responses to chronic endotoxin infusion in the rat". Thesis, University of Manchester, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376584.
Pełny tekst źródłaLove, Christopher K. "Investigation of RF Curing Parameters in Resin Infusion Molding". BYU ScholarsArchive, 2010. https://scholarsarchive.byu.edu/etd/2074.
Pełny tekst źródłaAdams, C. B., D. S. Street i John B. Bossaer. "Incidence of Cetuximab-related Infusion Reactions in Northeastern Tennessee". Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/etsu-works/2351.
Pełny tekst źródłaAdams, C. B., D. S. Street i John B. Bossaer. "Incidence of Cetuximab-related Infusion Reactions in Northeastern Tennessee". Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/2352.
Pełny tekst źródłaDanielsson, Sebastian. "Physiological characteristics of sodium lactate infusion during resistance exercise". Thesis, Gymnastik- och idrottshögskolan, GIH, Institutionen för idrotts- och hälsovetenskap, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:gih:diva-5782.
Pełny tekst źródłaTidigare studier som använt natriumlaktat infusion använde inte styrketräningsprotokoll, eller analyserade muskelbiopsier eller utförde könsspecifika analyser. Syfte och frågeställningar: Vi initierade ett projekt där styrketräning utfördes med låga eller höga nivåer av laktat som erhölls genom venös natriumlaktat infusion med det specifika syftet att undersöka och kartlägga fysiologisk karakteristiska av naturiumlaktat infusion under styrketräningsövning på helgrupps- och könsseparerad nivå. Följande frågeställningar inrättades; hur påverkar natriumlaktat infusion under styrketräning helblod- och plasma laktat, glukos, natrium, kalium, plasma volym genom hemoglobin och hematokrit, blod pH, muskellaktat- och muskel pH samt om skillnader i respons finns efter att könsspecifika analyser utförts på dessa variabler. Metod: En randomiserad, placebokontrollerad cross-over design implementerades där styrketräningsvana män (n = 8) och kvinnor (n = 8) besökte laboratoriet tre gånger för preliminäraför tester och träningsfamiliarisering. I efterföljande två experimentella försök anlände försökspersonerna i ett över nattligt fastande tillstånd. En baslinje biopsi extraherades från m. vastus lateralis och repeterade blodprover initierades med efterföljande 20 minuter av baslinje infusion av endera infusat i vilotillstånd med 0.05 mmol/kg/min infusionshastighet med ytterligare bolusdoser under efterföljande träning. Efter en kort uppvärmning utfördes unilaterala knäextensioner (6 x 8-10 reps vid 75% av 1-RM) med eller utan venös infusion av natrium laktat, med volymmatchande saltlösning som kontroll. Träningsbelastning och volym matchades mellan försök. Ytterligare fyra biopsier extraherades vid efter-träning, återhämtningsperiod, och efter 24 timmar. Resultat: Natriumlaktat respektive saltlösnings infusion under styrketräning gav signifikant högre blodlaktat med natriumlaktat infusion (6.78 ± 0.33 mmol/l mot 2.99 ± 0.17 mmol/l), plasmalaktat (8.86 ± 0.39 mmol/l mot 4.39 ± 0.22 mmol/l), blodnatrium (143 ± 0.4 mmol/l mot 142 ± 0.3 mmol/l), blod pH (7.42 ± 0.01 mot 7.34 ± 0.01), men lägre blod kalium (3.9 ± 0.1 mmol/l mot 4.2 ± 0.1 mmol/l), alla direkt efter träning. Natriumlaktat infusion framkallade huvudeffekt av försök och muskellaktat ökade från baslinje (8.5 ± 0.9 mmol·kg-1 dw mot 7.0 ± 0.6 mmol·kg-1 dw) till efter-träning (31.5 ± 2.8 mmol·kg-1 dw mot 26.9 ± 3.2 mmol·kg-1 dw) med natriumlaktat respektive saltlösnings infusion. Blodglukos, hemoglobin och muskel pH påverkades inte av natriumlaktat infusion. Slutsats: Användande av natriumlaktat infusion som metod under styrketräning kan effektivt användas som verktyg för att höja blod/plasma laktat, och i mindre utsträckning, muskellaktat. Emellertid är samtidig alkalisering av blod en sannolik följd.
Potential sex differences in the molecular response to resistance exercise with lactate infusion
Peña, Kristen Helen. "Characterization of an oxygen suspension used for intravenous infusion". Thesis, Massachusetts Institute of Technology, 2012. http://hdl.handle.net/1721.1/75714.
Pełny tekst źródłaCataloged from PDF version of thesis.
Includes bibliographical references (p. 45).
Oxygenated fluid mixture can be used to treat critically ill patients suffering from asphyxia, lung injury, and cardiac arrest. This oxygenated fluid delivered intravenously re-oxygenates the bloodstream, allowing for more time to resuscitate a patient before they suffer brain and/or organ damage. The concentration of the mixture is crucial for treatment as it affects the viscosity of the fluid, which in turn affects how well the fluid mixes with blood and how long it takes for oxygen to diffuse out of it. Evaluating the quality of fluid delivered and characterizing oxygenated fluid mixture at different concentrations was paramount. Since the fluid is a non-Newtonian emulsion, delivering a specific flow rate is challenging due to the following effects: degradation, compressibility, and shear thinning. Therefore, a testing machine was developed to aid in understanding the fluid dynamic behavior of the oxygenated mixture. The quality of the fluid can be assessed through measurement of the volume percentage, particle size distribution, oxygen tension, and rheometry. The data collected from the experiments will serve to create a model for delivering a specific volumetric flow rate of the fluid at atmospheric pressure.
by Kristen Helen Peña.
S.B.
O'Keefe, Zachary Scott. "Infusion: catalyzing progressive design strategies in the Knobtown District". Kansas State University, 2012. http://hdl.handle.net/2097/13688.
Pełny tekst źródłaDepartment of Landscape Architecture/Regional and Community Planning
Blake Belanger
Sustainable landscape design is generally understood in relation to three principles—ecological health, social justice, and economic prosperity. However, people have neglected to recognize the significance of their impact on the environment. The real conflict begins to address our relationship with the environment and how we attempt to reconnect and reverse centuries of environmental degradation. As a society, we lie at the intersection of the past and the future, presenting us the opportunity to think organically. Harboring values much different from post-industrial thinking, organic values work with nature rather than against it. However, most contemporary processes are not organic in nature. Rather they are products of our isolated way of thinking; a limited form of consciousness that arrogantly declares that we are the greatest intelligence on Earth. This consciousness has taught us that for our survival, it is our duty to subdue nature, relating to it as a resource for implementing how and what our minds invent. We have learned to relate to nature as a commodity rather than respect it as our community. Infusion seeks to establish this connection by creating a Transit-Oriented Development in the Knobtown District that uses the power of aesthetics to promote and inspire educational exploration, cultural expression, and ethical revelation of sustainable design. Supporting this solution is a four-part foundational framework that identifies specific design principles that are envisioned to improve the way we relate to our environment through aesthetic eminence educational exploration, cultural expression and ethical revelation. The conceptualized framework is structured to be adaptable for many design situations becoming a foundation for the way in which we design and interact with form and space. In its final state, Infusion communicates the significance of these essential design principles and how the new Knobtown District can become an important part of the Rock Island Corridor.
Lindemalm, Josefin, i Anna Akkawi. "The New Infusion Pump System at New Karolinska Solna". Thesis, KTH, Medicinsk teknik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-210183.
Pełny tekst źródłaReid, Peter Geddes. "Cardiovascular and respiratory effects of adenosine infusion in man". Thesis, University of Edinburgh, 1991. http://hdl.handle.net/1842/27252.
Pełny tekst źródłaLinderoth, Henrik. "Från vision till integration : infusion av telemedicin : en översättningsprocess". Doctoral thesis, Umeå universitet, Handelshögskolan vid Umeå universitet (USBE), 2000. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-66623.
Pełny tekst źródładigitalisering@umu
Batiston, Michele Cristina. "O uso da bomba de infusão inteligente em pacientes hospitalizados". Botucatu, 2018. http://hdl.handle.net/11449/154826.
Pełny tekst źródłaResumo: O objetivo deste trabalho foi avaliar a evidência científica disponível sobre o uso das bombas de infusão inteligentes em pacientes hospitalizados. Foi realizado um estudo, de acordo com Diretrizes Metodológicas propostas pelo Ministério da Saúde para a elaboração de pareceres técnico-científicos (PTC). Foi realizada uma busca até 14 de novembro de 2017 nas bases de dados The Cochrane Library, EMBASE, PubMed, Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) e de Avaliações de Tecnologias de Saúde (ATS), não houve restrição de idioma e ano de publicação do artigo. Os resultados das bases de dados foram agrupados e eliminados os estudos em duplicatas. Em seguida, aplicados os critérios de elegibilidade para os títulos e resumos, restando 51 estudos para leitura completa. Após leitura dos artigos na íntegra, foram selecionados 6 estudos, que incluíram revisão sistemática sem metanálise, três estudos observacionais sem comparador e dois estudos observacionais do tipo antes e depois. Os estudos não apresentaram dados conclusivos para redução do número de eventos ocorridos. Para a interceptação de erros/prevenção de erros, os estudos demonstraram que a bomba inteligente interceptou e impediu diversos erros como frequência, dose e programação erradas. Para os custos, o estudo de revisão sistemática sem metanálise inclui um estudo que apresentou redução de custos da Bomba de Infusão Inteligente pelos possíveis eventos adversos evitáveis. A recomendação é incerta,... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: Title: Intelligent Infusion Pump versus Conventional Infusion Pump: Comparison of cost and safety. Recommendation for the use of technology: ( ) In favor of (X) Uncertain ( ) Against Brief justification for the recommendation: Studies with little scientific evidence, the costs with the materials, the need to qualify, the construction of a library, among other strategies. Population: Patients hospitalized Technology: Intelligent Infusion Pumps Comparator: Conventional Infusion Pumps Search and analysis of scientific evidence: A search was performed to 2017, November 14 in the databases The Cochrane Library, EMBASE, PubMed and Latin American, Caribbean Literature in Health Sciences (LILACS) and the Health Technology Assessment (ATS). There was no language restriction and year of publication of the article. The results of the databases were grouped and the duplicate studies were eliminated. Then, the eligibility criteria for titles and abstracts were applied, leaving 51 studies for complete reading. After reading the articles in full, 06 studies were selected. Summary of results of selected studies: Six studies were included: one systematic review without meta-analysis, three observational studies without comparator, and two before-after observational studies. The studies did not present conclusive data to reduce the number of events that occurred. For error interception / error prevention, studies have shown that the smart pump intercepted and prevented various errors such as f... (Complete abstract click electronic access below)
Mestre
Souto, Maria Teresa de Mello Rêgo. "Estudos clínicos da infusão contínua de fentanil, quetamina ou lidocaína sobre o requerimento de isoflurano em cavalos submetidos à cirurgia de artroscopia". Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/10/10137/tde-27022012-110748/.
Pełny tekst źródłaVolatile anesthetics are commonly used in horse anesthesia in surgical procedures over 60 minutes, resulting in a dose-dependent cardiovascular depression, contributing to a high mortality rate. Thus, the aimed this study was determine whether fentanyl continuous rate infusion would be able to reduce end tidal isoflurane, promoting intraoperative cardiovascular stability and a better recovery after arthroscopic surgery, when compared to lidocaine or ketamine infusion during maintenance of anesthesia with isoflurane. Therefore, 20 horses aging 3-8 years and weighing 350 to 500 kg underwent arthroscopic surgery in dorsal recumbence. The animals were randomly divided into four groups: GL (1.5 mg/kg bolus and 0.15 mg/kg/min infusion rate of lidocaine), GQ (2 mg/kg bolus and 0.2 mg/kg/min infusion of ketamine); GF (7µg/kg bolus and 0.7 mg/kg/min infusion rate of fentanyl) and GI did not receive any adjuvant infusion. Cardiovascular parameters (HR, MBP, SBP and DBP), ventilatory and oxygenation (PaO2, PaCO2, Cst and Rva), end tidal isoflurano [ISO] (Fexp%), and quality of recovery were evaluated. Regarding [ISO] (Fexp%) the highest decreases were observed at the time 30bolus in all groups with adjuvants, in comparison to base line -GL (1.50 to 0.90%) GQ (1.44 to 0.96 %) and GF (1.32 to 0.96%). At 15 minutes after the end of continuous rate infusion of fentanyl and lidocaine, expired fraction of isoflurane was increased 25% for GL and 45% for GF. Although there was no statistical difference, GF showed lower recovery score - 16.8 points, while 24.6 for GL, 30.0 for GQ and 31.8 points for GI. In conclusion, fentanyl was able to reduce end tidal isoflurane to 43%, with no side effects at recovery time after re-sedation with xylazine 0.5 mg / kg.
Mendes, Marina Ceccato [UNESP]. "Efeitos cardiorrespiratórios da infusão contínua de amitraz ou de romifidina em equinos anestesiados com isofluorano. Determinação das concentrações plasmáticas do amitraz". Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/101150.
Pełny tekst źródłaFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Com base na ação do amitraz (AMZ) e da romifidina (RMF) em receptores alfa-2 adrenérgicos e nas possíveis vantagens da associação destes fármacos com agentes inalatórios para uma anestesia geral segura, compararamse os efeitos clínicos, cardiocirculatórios e hemogasométricos da infusão contínua (IC) de AMZ ou de RMF associada ao isofluorano. Relacionaram-se os efeitos observados à concentração plasmática do amitraz (CPA) e investigaram-se possíveis efeitos farmacodinâmicos do diluente lipídico (DIL) utilizado na sua formulação. A medicação pré-anestésica (MPA) intravenosa (IV) para cada grupo foi: RMF - 60 μg/kg; AMZ - 0,2 mg/kg; DIL - 60 μg/kg de RMF. Induziu-se a anestesia com midazolam (0,1 mg/kg IV) e cetamina S(+) (0,2 mg/kg IV). A manutenção foi feita com 1,3 V% de isofluorano associado às ICs (RMF - 60 μg/kg.h; AMZ - 0,2 mg/kg.h; DIL - 0,1 mL/kg.h) por 60 minutos. Um minuto após a MPA a CPA média foi 396 ng/mL, aumentando durante a IC (de 93 ng/mL para 257 ng/mL) e diminuindo na recuperação, atingindo 47 ng/mL em 60 minutos. A RMF causou boa sedação e indução, com intubação fácil; manteve a FC estável e aumentou gradualmente a PAM, alterando pouco o CO2; resultou em recuperação ideal. O AMZ causou sedação leve e manteve planos anestésicos mais superficiais do que a RMF, com hipotensão durante a IC; a indução e a intubação foram de boa qualidade; o miorrelaxamento foi maior do que com RMF; a recuperação não teve boa qualidade. O DIL não causou sedação e resultou em recuperação de má qualidade, sendo inerte em relação aos efeitos do AMZ. Concluiu-se que há possibilidade do uso clínico do AMZ, ficando indicados estudos complementares.
Based on the action of amitraz (AMZ) and romifidine (RMF) on alpha-2 adrenergic receptors and in the possible advantages of combining them with inhalation anesthetics for a safe general anesthesia, the clinical, cardiocirculatory and hemogasometric effects of the continuous infusion (CI) of AMZ or RMF in association with isoflurane anesthesia were compared. The observed effects were related to the AMZ plasmatic levels (APL). The existence of pharmacodynamic effects of the lipid vehicle (LV) used for AMZ formulation was also investigated. The intravenous (IV) pre-anesthetic medications (PAM) were: RMF - 60 μg/kg; AMZ - 0.2 mg/kg; LV - 60 μg/kg de RMF. Anesthesia was inducted with midazolam (0.1 mg/kg IV) and S-ketamine (0.2 mg/kg IV) and maintained with 1.3 V% isoflurane, in association with the CIs (RMF - 60 μg/kg.h; AMZ - 0.2 mg/kg.h; LV - 0.1 mL/kg.h) for 60 minutes. One minute after PAM, APL was 396 ng/mL. During the CI, APL increased from 93 to 257 ng/mL. On recovery, APL decreased to 47 ng/mL in 60 minutes. With RMF there were good sedation and induction and the intubation was easy; HR was stable and MAP increased, with little CO2 alterations; the recovery was ideal. AMZ had less sedative effect and reached superficial anesthesia compared to RMF, with hypotension during CI; there were good induction and easy intubation; miorelaxation was greater with AMZ than with RMF; recovery was not good. The LV did not induce sedative effects and resulted in a poor recovery; it did not influence AMZ effects. The clinical use of AMZ is possible, but further studies are indicated.
Castro, Vanessa Bastos [UNESP]. "Efeitos hemodinâmicos do cloridrato de dexmedetomidina administrado por infusão intravenosa contínua em cães anestesiados com propofol". Universidade Estadual Paulista (UNESP), 2008. http://hdl.handle.net/11449/105629.
Pełny tekst źródłaCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
O emprego de procedimentos de anestesia intravenosa total em cães tem sido mais freqüente, devido ao melhor conhecimento do perfil farmacocinético dos fármacos empregados. Como ainda não existe um único fármaco que produza todas as características desejáveis em uma anestesia geral, há a necessidade de se associar ao hipnótico, agentes com propriedades analgésicas. O objetivo desse estudo foi avaliar os efeitos hemodinâmicos causados pela associação do cloridrato de dexmedetomidina, nas doses de 1 e 2 μg/kg/h, e propofol na dose de 0,3 mg/kg/min, administrada em infusão intravenosa contínua em cães, bem como o tempo de recuperação anestésica após duas horas de infusão. Seis cães, clinicamente sadios, sem raça definida, pesando 17,6±1,8 kg, foram submetidos a três tratamentos com intervalo de uma semana e em seqüência aleatória. Todos os animais foram inicialmente anestesiados com isofluorano a 5V% com fluxo de 3 l/min de O2. Após a indução e intubação, os animais foram posicionados em decúbito lateral esquerdo e mantidos com isofluorano na concentração de 1,8V%. As veias cefálicas e a artéria dorsal podal foram cateterizadas e um cateter de Swan Ganz 5F foi introduzido pela veia jugular. Após fixação dos cateteres na pele, a administração do isofluorano foi interrompida. Os cães permaneceram despertos por 1 hora, e após esse período, foi realizada a avaliação das variáveis hemodinâmicas. Em seguida os cães receberam um dos seguintes tratamentos: Controle: indução com propofol (6 mg/kg/30s) e solução de NaCl 0,9% (5 ml/10min) seguida de manutenção com propofol (0.3 mg/kg/min) e NaCl 0,9% (4 ml/h); Dex 1: indução com propofol (6 mg/kg/30s) e cloridrato de dexmedetomidina (1 μg/kg/10min) seguida de manutenção com propofol (0.3 mg/kg/min)...
Total intravenous anesthesia in dogs has been more frequently used, the pharmacokinetic profile of the new drugs is better understood. No injectable anesthetic produces all of the components of a general anesthesia, it is required to associate additional analgesics with hypnotic. The aim of this study was to evaluate the hemodynamic effects caused by the association of 1 and 2 μg/kg/h of dexmedetomidine and 0,3 mg/kg/min of propofol, administered by continuous intravenous infusion, as well time of anesthetic recovery after 2 hours of infusion. Six healthy dogs weighting 17,6±1,8 kg were randomly allocated to 3 treatments with at least one week intervals between each treatment. All animals were initially anesthetized with 5V% of isoflurane and 3 l/min of oxygen. After induction and intubation, the animals were posicionated in left lateral recumbence and maintained with 1.8% end tidal. All animals were instrumented with a cephalic veins and arterial catheter and a Swan Ganz catheter in order to a monitor hemodynamic parameters. After instrumentation isoflurane was interrupted and animals were awake and remained awake for one hour. After that, baselines parameters were taken. Dogs received each one of these treatments: Control: was induced with propofol (6 mg/kg/30s) and saline (5 ml/10 min), maintenance was with propofol (0.3 mg/kg/min) and saline (4 ml/h). Dex 1 was induced with propofol (6 mg/kg30s) and dexmedetomidine (1 μg/kg10 min), maintenance with propofol (0.3 mg/kg/min) and dexmedetomidine (1 μg/kg/h). Dex 2 was induced with propofol (6 mg/kg30s) and dexmedetomidine (2 μg/kg/10min), maintenance with propofol (0.3 mg/kg/min) and dexmedetomidine (2 μg/kg/h) during 120 minutes. The parameters (HR, SBP, MAP, DAP, CI, SI, CVP, PAP, POPA, SVRI, PVRI, RR, ETCO2, SaO2, pHa, PaO2, PaCO2, HCO3, Hb, CaO2, IDO2, temperature) were taken at 15, 30, 60, 90 e 120 minutes after induction... (Complete abstract click electronic access below)
Beier, Suzane Lilian [UNESP]. "Infusão alvo-controlada com propofol e remifentanil: estudo experimental em cães". Universidade Estadual Paulista (UNESP), 2007. http://hdl.handle.net/11449/105646.
Pełny tekst źródłaFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Os modernos sistemas de infusao alvo-controlada (TCI), usados para a inducao e manutencao da anestesia, permitem que a velocidade de infusao seja ajustada atraves da utilizacao de avancados softwares alimentados com parametros farmacocineticos, de modo a assegurar uma adequada profundidade da anestesia e uma rapida e eficiente recuperacao. O objetivo inicial deste estudo foi determinar a concentracao plasmatica calculada de propofol (Cpcalculada) determinada por meio de estimulacao eletrica (50V, 50 Hz e 10 ms). Na segunda fase, o objetivo foi investigar a performance do uso de um sistema de infusao alvo-controlada de propofol usado isoladamente ou associado ao remifentanil. Paralelamente foram avaliados as respostas hemodinamicas e o periodo de recuperacao. A Performance e determinada pela Mediana da Performance do erro (MDPE), e a Mediana Absoluta da Performance do erro (MDAPE), sendo considerada clinicamente aceitavel uma MDPE de ate 20% e a MDAPE de ate 40%. Seis caes adultos saudaveis (26,6} 3,6kg) foram alocados aleatoriamente em 2 grupos com um intervalo de uma semana entre os experimentos. GI = TCI de propofol e G II = TCI de propofol + remifentanil. Os resultados foram analisados estatisticamente atraves da analise de variancia seguida pelo teste gt-Studenth. Foi considerado como significante um p<0,05. Houve uma reducao na frequencia cardiaca e indice cardiaco em GII, enquanto a pressao venosa central e a pressao de oclusao da arteria pulmonar aumentaram significativamente em GII comparado a GI. Os resultados obtidos para o grupo propofol foram de MDPE = 16,3% e MDAPE = 32,1% e para o grupo propofol+remifentanil foram de MDPE = 6,8% e MDAPE = 36,5%. A Cp50calculada foi de 2,0Êg.ml-1 (GI) e de 0,9Êg.ml-1 (GII)...
The target-controlled infusion systems (TCI), designed to keep the drug concentration in the bloodstream constant, are controlled by state-of-art software based upon pharmacokinetic models. These models have been designed for each species to produce an adequate anesthetic depth and fast and efficient recover. The aim of this study was to establish the predicted plasmatic concentration (Cppredicted) based upon electric stimulus (50V, 50 Hz and 10 ms). In a second phase, the aim was to investigate the anesthetic performance of the TCI of propofol used alone and associated with remifentanil. Moreover, haemodynamic parameters and anesthesia recovery time were evaluated. The performance was established based on the Median Performance error (MDPE < 20%) and Absolute Median Performance error (MDAPE < 40%). Six clinically normal dogs (26.6 l 3.6 kg) were randomly divided in 2 groups with at least one week between experiments. G1 = TCI of propofol alone; G2 = TCI of propofol + remifentanil. The statistical analysis was based on Student's t-distribution test, with alpha set at 0.05. Heart rate (HR) and cardiac index (CI) were significantly decreased after propofol + remifentanil (G2) infusion administration until the end, while central venous pressure (CVP) and pulmonary capillary wedge pressure (PCWP) were significantly increased. The G1 group demonstrated MDPE of 16.3% and MDAPE of 32.1%, whereas the G2 group had MDPE of 6.8% and MDAPE of 36.5%. The average Cp50predict for G1 was 2,0ìg.ml-1 and for G2 was 0,9ìg.ml-1. The evaluation of these parameters and the control of the anesthetic depth suggested that the TCI stanpump could be considered clinically acceptable in dogs. The remifentanil enhances the propofol's CPpredict in an average of 56.7%; however, haemodynamic side effects were detected.
Hatschbach, Eduardo [UNESP]. "Estudo comparativo entre anestesia venosa total alvo-controlada e por infusão contínua em cães pré-tratados com levomepromazina e tratados com propofol e remifentanila". Universidade Estadual Paulista (UNESP), 2007. http://hdl.handle.net/11449/105639.
Pełny tekst źródłaCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
A anestesia venosa total possui muitas vantagens, não polui ar ambiente, fácil de usar em lugares remotos, estabilidade cardiovascular e boa qualidade de recuperação. O propofol, devido sua farmacologia, é um dos fármacos mais usados em infusões contínuas. Recentes avanços têm acontecido na anestesia venosa total com a utilização de infusões alvo controlada, baseados em simulações farmacodinâmicas e farmacocinéticas dos fármacos em tempo real, inclusive na Medicina Veterinária. Em função disso, pretendeu-se colocar em prática este tipo de anestesia, utilizando-a em cadelas para a realização de cirurgias de ovariosalpingohisterectomia. Para isso foram anestesiadas 20 cadelas, após o consentimento livre e esclarecido dos proprietários. Sendo divididos em dois grupos (GI e GII). Em GI, os animais foram pré-tratados com levomepromazina na dose de 0,5mg/kg IV e anestesiados com propofol por infusão alvo controlada na dose de indução de 3,5æg/ml e na dose de manutenção de 1,5 æg/ml IV, através bomba de infusão Harvard pump, associado com remifentanila na dose de 0,3æg/kg/min, através de bomba de seringa. Em GII, os animais receberam o mesmo tratamento de GI, só que ao invés de receberem o propofol por infusão alvo controlada, receberam o propofol a 5mg/kg como dose de indução e como manutenção, receberam o propofol em infusão contínua de velocidade fixa, na dose de 0,2mg/kg/min. Assim, compararam-se as duas técnicas de infusão, a de velocidade fixa e a alvo controlada, concluindo-se que as doses de propofol utilizadas em ambas as técnicas, após o pré-tratamento de levomepromazina e associadas ao opióide, foram eficazes para a realização cirúrgica, promovendo bradicardia e discreta hipotensão, porém estabilidade hemogasométrica e respiratória...
Total venous anesthesia has many advantages as it does not pollute environmental air, can be easily used in remote sites, provides cardiovascular stability and good recovery quality. Due to its pharmacology, propofol is one of the most frequently used drugs in continuous infusions. Recently, advances have also been observed in total venous anesthesia with the use of target-controlled infusions based on real-time pharmacodynamic and pharmacokinetic drug simulations in Veterinary Medicine. As a result, this study aimed at applying this type of anesthesia by using it in female dogs for the performance of ovariosalpingohysterectomy surgery. To that end, twenty female dogs were anesthetized after free consent was given by their owners. The animals were divided into two groups (GI and GII). In GI, the dogs were pre-treated with methotrimeprazine at a dose of 0.5mg/kg IV and anesthetized with propofol by target-controlled infusion at an induction dose of 3.5æg/ml and a maintenance dose of 1.5 æg/ml IV by means of a Harvard infusion pump associated with remifentanil at a dose of 0.3æg/kg/min by means of a syringe pump. In GII, the animals received the same treatment as that given to GI, except that instead of receiving propofol by target-controlled infusion, they were given propofol at 5mg/kg as an induction dose. As maintenance, they received propofol by single-speed continuous infusion at a dose of 0.2mg/kg/min. Hence, two infusion techniques, fixed-speed infusion and target-controlled infusion, were compared, leading to the conclusion that the doses of propofol used in both techniques, after pre-treated with methotrimeprazine, associated with the opioid were efficient for surgery performance as they promoted bradycardia and discreet hypotension, but hemogasometric and respiratory stability, futher good muscle relaxation, more evident in fixed-speed infusion... (Complete abstract click electronic access below)
Aldaek, Taher A. A. "Untersuchungen zur Beeinflussung der Konzentrationen von Glukose und Phosphat in Blut und Harn bei Milchkühen durch eine Glukoseinfusion". Giessen VVB Laufersweiler, 2009. http://d-nb.info/996005560/04.
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