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Artykuły w czasopismach na temat "I-838"

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CERSONSKY, JEFF. "Cocaine Abusers as Mothers". Pediatrics 82, nr 1 (1.07.1988): 136. http://dx.doi.org/10.1542/peds.82.1.136.

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To the Editor.— I have two points to raise concerning the article by Chasnoff et al (Pediatrics 1987;80:836-838). First, the history of alcohol intake given was consistent with dependency. As an addictionologist working with teenage alcoholics and addicts, I can give you a pretty good assurrance that the alcohol intake related by this mother was a gross underestimation. The physical features of this child lead one to believe that the child did suffer from prenatal maternal abuse and should have been further discussed.
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CHASNOFF, IRA J. "Cocaine Abusers as Mothers". Pediatrics 82, nr 1 (1.07.1988): 136–37. http://dx.doi.org/10.1542/peds.82.1.136a.

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In Reply.— I would like to thank Dr Cersonsky for his comments regarding our article (Pediatrics 1987;80:836-838). I certainly agree that the social aspects of a case regarding maternal substance abuse in pregnancy are important in the ultimate prognosis for the exposed child. In our experience with addicted pregnant women, our major work has been pointed toward the importance of early intervention in pregnancy. Unfortunately, the woman reported in this article was not referred to our program, and her physicians never obtained any type of substance abuse history during the pregnancy.
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Li, Yinkui, Xiaoxiao Qin, Wen Li, Xiaoling Wang i Haicheng Ma. "Connected even factors in k-tree". Open Mathematics 18, nr 1 (29.12.2020): 1601–5. http://dx.doi.org/10.1515/math-2020-0106.

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Abstract A connected even {[}2,2s] -factor of a graph G is a connected factor with all vertices of degree i(i=2,4,\ldots ,2s) , where s\ge 1 is an integer. In this paper, we show that a \tfrac{k+1}{s+2} -tough k-tree has a connected even {[}2,2s] -factor and thereby generalize the result that a \tfrac{k+1}{3} -tough k-tree is Hamiltonian in [Hajo Broersma, Liming Xiong, and Kiyoshi Yoshimoto, Toughness and hamiltonicity in k-trees, Discrete Math. 307 (2007), 832–838].
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Li, Yinkui, Xiaoxiao Qin, Wen Li, Xiaoling Wang i Haicheng Ma. "Connected even factors in k-tree". Open Mathematics 18, nr 1 (1.01.2020): 1601–5. http://dx.doi.org/10.1515/math-2020-0106.

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Abstract A connected even [ 2 , 2 s ] {[}2,2s] -factor of a graph G is a connected factor with all vertices of degree i ( i = 2 , 4 , … , 2 s ) i(i=2,4,\ldots ,2s) , where s ≥ 1 s\ge 1 is an integer. In this paper, we show that a k + 1 s + 2 \tfrac{k+1}{s+2} -tough k-tree has a connected even [ 2 , 2 s ] {[}2,2s] -factor and thereby generalize the result that a k + 1 3 \tfrac{k+1}{3} -tough k-tree is Hamiltonian in [Hajo Broersma, Liming Xiong, and Kiyoshi Yoshimoto, Toughness and hamiltonicity in k-trees, Discrete Math. 307 (2007), 832–838].
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Fang, Ping, Kyle R. Cron, Oanh Pham, Julie R. Janes, John Brandenburg, Fauna Yarza, Bret Peterson, Christopher Thanos, Chan Whiting i Akshata R. Udyavar. "Abstract 576: ACTM-838, a novel immunotherapy that enriches in solid tumors after IV dosing and comprehensively reverses the immunosuppressive TME to promote durable anti-tumor immunity". Cancer Research 83, nr 7_Supplement (4.04.2023): 576. http://dx.doi.org/10.1158/1538-7445.am2023-576.

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Abstract ACTM-838 is an avirulent bacterial immunotherapy that encodes an engineered IL-15 (IL-15plex) and a constitutively active STING variant (eSTING). The ACTM-838 strain is a highly modified, attenuated S. Typhimurium that lacks several major inflammatory and immunogenic components on the surface of the microbe and is designed to naturally and specifically enrich in the tumor microenvironment (TME) via auxotrophic dependency on metabolites of the adenosine pathway and purines, to achieve tumor-specific payload delivery. ACTM-838 was selectively internalized by phagocytic, primary human antigen presenting cells (APCs) but not endothelial cells. ACTM-838 was stable in human whole blood and is not inactivated by complement. Human macrophage uptake of labeled ACTM-838 led to acidic lysosomes and nuclear delivery with a concomitant increase in expression of encoded IL-15plex and eSTING payloads such as IL-15, IRF3 reporter activity and IFN ⍺/β secretion, respectively. Primary human and murine macrophages polarized towards a dual co-stimulatory and phagocytic M1/M2 dual phenotype in response to ACTM-838. ACTM-838 delivered eSTING payload in STING knockout macrophages and induced significantly higher Type I IFN production over a negative control strain. IV delivered ACTM-838 showed dose and payload dependent tumor enrichment and potent single-agent efficacy in two independent syngeneic tumor models, EMT6 (orthotopic) and MC38. Sustained memory anti-tumor immunity upon tumor rechallenge in cured animals was demonstrated. ACTM-838 treated tumors exhibited a significant increase in human IL-15plex protein payload. ACTM-838 as a single agent induced profound immune reprogramming and remodeling of the TME over time through increased infiltration and activation of myeloid, NK, B and cytolytic CD8 T cells, MHC class I and II, antigen presentation as well as decreased Treg, PD1+Lag3+ exhausted T cells, and a remodeled stromal signature, as assessed by bulk RNAseq, and confirmed by flow cytometry. Synergistic anti-tumor activity was observed in multiple tumor models when ACTM-838 was dosed in combination with anti-PD1, safely inducing complete responses. No significant body weight loss or death was observed in any treatment regimens of ACTM-838 alone (single or multiple doses) or in combination with anti-PD1. Analyses of public RNAseq datasets from patients with primary or metastatic disease revealed cancer types with high levels of myeloid infiltration and adenosine enrichment, suggesting that ACTM-838 efficacy could provide benefit in these indications. ACTM-838 is a novel immunotherapy delivering IL-15plex + eSTING payloads to phagocytic APCs, inducing a durable anti-tumor immune response, after IV dosing. It possesses a compelling safety profile, and is currently in IND-enabling, preclinical development. Citation Format: Ping Fang, Kyle R. Cron, Oanh Pham, Julie R. Janes, John Brandenburg, Fauna Yarza, Bret Peterson, Christopher Thanos, Chan Whiting, Akshata R. Udyavar. ACTM-838, a novel immunotherapy that enriches in solid tumors after IV dosing and comprehensively reverses the immunosuppressive TME to promote durable anti-tumor immunity [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 576.
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Peelen, E., A. Muehler, D. Vitt i H. Kohlhof. "P064 IMU-838, a Small Molecule DHODH Inhibitor in Phase 2 Clinical Trial for Ulcerative Colitis, Shows Potent Anti-inflammatory Activity in Cell-Culture-Based and In Vivo Systems". Journal of Crohn's and Colitis 16, Supplement_1 (1.01.2022): i172—i173. http://dx.doi.org/10.1093/ecco-jcc/jjab232.193.

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Abstract Background IMU-838 (vidofludimus calcium) is a well-tolerated and orally available small molecule inhibitor of dihydroorotate dehydrogenase (DHODH) and is currently in phase 2 clinical development for ulcerative colitis (UC). Here, we investigated the effect of IMU-838 on different immune cell subsets and analysed the mechanism of action in more detail in T cells. Methods The effect of IMU-838 on regulatory macrophages (Mregs) was investigated by adding IMU-838 or anti-TNFα antibodies (infliximab, adalimumab), alone or in combination, in a mixed lymphocyte reaction assay, determining Mregs (CD206+CD14+) by FACS analysis. To investigate the effect of IMU-838 on human T and B cells, PBMC were stimulated with PHA (48h) or Oligonucleotide 2006-PTO (70h), respectively. An affinity-dependent effect of IMU-838 was assessed on CD8 T cells from OT-I and OT-III mice, containing a high and a low affinity T cell receptor (TCR), respectively, for OVA257-264 peptide. These cells were stimulated with ovalbumin (OVA) peptide loaded splenocytes or anti-CD3/anti-CD28 for 3 days. Oxidative phosphorylation (OXPHOS) and glycolysis in murine T cells was investigated by the Seahorse/Agilent technique in murine CD4 and CD8 T cells activated with anti-CD3/anti-CD28 with or without IMU-838. Results IMU-838 slightly induced Mregs, but strongly and dose-dependently decreased TNFα and IL-6 secretion. Anti-TNFα antibodies alone strongly induced Mregs, but also increased IL-6 levels. When IMU-838 was added, Mregs induction was even higher, and IL-6 was reduced. Besides reducing proinflammatory cytokines secreted by macrophages, IMU-838 also inhibits proliferation of activated B and T cells, as well as inflammatory T cell cytokine secretion, IL-17A, IL-17F and IFNγ, and increased apoptosis up to 3-fold compared to vehicle control. By investigating IMU-838’s role on affinity related activity status of T cells, it was shown that IMU-838 strongly inhibited cell proliferation in the peptide stimulated high affinity, but not in the low affinity, CD8 T cells. Peptide stimulated high affinity T cells show an upregulation of OXPHOS and glycolysis pathways, which are involved in the generation of the cell’s energy supply, compared to low affinity cells. IMU-838 strongly inhibited OXPHOS and glycolysis in both CD4 and CD8 T cells. Conclusion IMU-838 reduces the proinflammatory immune cell response by inducing Mregs, reducing pro-inflammatory cytokine secretion and reducing immune cell proliferation. DHODH is only important in cells that received a strong stimulus and are highly metabolically active. Therefore, IMU-838 will only specifically target these cells and will still allow for a normal immune response, representing a huge safety advantage for treatment of IBD patients.
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Kehoe, Haixing, Alexandre Iannello, Keith Cheung, Bret Peterson, Marie Marotel, Sara Tribble, Hailey He i in. "853 ACTM-838: a microbial-based immunotherapy that delivers combination IL-15 + engineered STING to tumor-resident APCs after IV dosing in T-cell excluded solid tumors". Journal for ImmunoTherapy of Cancer 9, Suppl 2 (listopad 2021): A894. http://dx.doi.org/10.1136/jitc-2021-sitc2021.853.

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BackgroundIn a metastatic setting, systemically-administered therapies that overcome the immunosuppressive tumor microenvironment to promote T-cell recruitment and T-cell cytolytic function will be required to elicit durable anti-tumor immunity. To accomplish this, the STACT (S. Typhimurium-Attenuated Cancer Therapy) platform was developed. STACT is a live bacterial product that has been highly modified using precision genome editing for the following properties: (1) enhanced tolerability after IV dosing, (2) tumor-specific enrichment, (3) phagocytosis by tumor-resident antigen-presenting cells (APCs) with a lack of epithelial cell infectivity, (4) multiplexed genetic cargo delivery, and (5) attenuation of bacterial pathways that impair CD8+ T-cell function. An extensive screening campaign was performed to identify ideal encoded immunomodulatory payload combinations delivered by STACT for efficacy against T-cell excluded tumors.MethodsChromosomal edits to the STACT platform strain were made using PCR. A panel of immunomodulatory proteins, including cytokines, type I interferon (IFN)-inducing factors, co-stimulatory receptors, checkpoint antibodies and TGFβR-Fc decoys were tested for combinatorial potency using STACT. An engineered STING (eSTING) was designed through an extensive protein engineering campaign to identify optimal variants. Combinations were evaluated in primary human APCs using in vitro functional assays, where STACT IL-15Rα-IL-15 (IL-15) + eSTING (ACTM-838) emerged as a lead candidate. ACTM-838 was then evaluated in multiple murine tumor models for therapeutic efficacy and mechanism, as well as tolerability in rodents and primates after systemic administration.ResultsCombinatorial target profiling led to the discovery of ACTM-838, a STACT encoding IL-15 + eSTING. In vitro, ACTM-838 payloads synergistically produced high levels of type I IFN and T-cell recruitment and activation factors from primary human APCs. In vivo, ACTM-838 demonstrated a high degree of complete tumor responses that were entirely CD8+ T-cell dependent. In an autochthonous breast cancer model that lacks any significant lymphocyte infiltrate, ACTM-838 was able to uniformly enrich in each spontaneous lesion to high levels after IV dosing and resulted in significant CD8+ T-cell infiltration. In primates, ACTM-838 was well-tolerated, rapidly cleared, and elicited minimal cytokine response after IV dosing.ConclusionsACTM-838 is a highly attenuated, precision genome-engineered bacterial immunotherapy that delivers IL-15 + eSTING to phagocytic APCs of the solid tumor microenvironment after systemic administration. In preclinical studies, ACTM-838 promotes CD8+ T-cell mediated tumor clearance in T-cell excluded tumors and elicits durable anti-tumor immunity, and is well tolerated in primates. Based on these data, ACTM-838 was nominated for clinical development and has entered cGMP manufacturing and IND-enabling studies.Ethics ApprovalAll animals were used according to protocols approved by an Institutional Animal Care and Use Committee and maintained in specific pathogen-free conditions in a barrier facility.
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Reeve, Michael D. "Ovid Met. 15, 838: an apology (of sorts) to Loriano Zurli". AL. Rivista di studi di Anthologia Latina 13 (listopad 2022): 95–102. http://dx.doi.org/10.1484/j.alat.5.133359.

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Lu, William, Kyle Cron, Julie Janes, Leigh Berryman, Gurvinder Singh, Christopher Thanos i Akshata Udyavar. "Abstract 736: ACTM-838 safely and comprehensively re-activates the immunosuppressive TME by exploiting myeloid biology intrinsic in many cancers". Cancer Research 84, nr 6_Supplement (22.03.2024): 736. http://dx.doi.org/10.1158/1538-7445.am2024-736.

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Abstract ACTM-838 is a genetically modified bacterial vehicle encoding a DNA plasmid with two engineered payloads, IL-15plex and constitutively active eSTING. The bacterial vehicle is a highly attenuated S. typhimurium, engineered to facilitate safe IV administration. ACTM-838 is designed to specifically enrich in the TME via auxotrophic dependency on extracellular adenosine and purine metabolites. ACTM-838 is then selectively internalized by tumor-resident myeloid cells achieving tumor-specific payload delivery. Previously, we showed ACTM-838 exhibited significant and durable anti-tumor efficacy across syngeneic tumor mouse models (EMT6 breast, MC38 colon) and MMTV-PyMT GEMM. To elucidate TME changes induced by ACTM-838, EMT6 tumors were analyzed post-treatment by scRNA-seq, which demonstrated that ACTM-838 induced significant transcriptional changes in several cell populations in the TME. Cytolytic pathways were upregulated in T and NK cells, while type I IFN and PDL1 were upregulated in myeloid populations consistent with previous bulk RNAseq analyses. To understand the tolerability and safety of ACTM-838, a GLP toxicology study was performed on naïve cynomolgus monkeys (NHP). No ACTM-838-related clinical or veterinary observations were reported at any dose level. Acute dose-dependent increases in serum cytokines were observed at 4 hours which reverted to baseline by 24 hours. ACTM-838 was cleared from blood by 24 hours post-dose with no significant shedding in urine or feces. ACTM-838 was only detected in the spleen in 2 and 1 animals at 22- and 49-days post treatment, respectively. Pre-existing ADA was observed in some animals with subsequent increases in ADA upon dosing in most animals. However, no correlation of serum ADA and blood PK levels suggested that the presence of ADA does not impact drug stability. The ACTM-838 mechanism of action requires high levels of adenosine or purine metabolites to enrich and colonize the TME as well as phagocytic internalization by tumor-intrinsic myeloid cells to achieve tumor-specific payload delivery. Myeloid cells comprise roughly half of all cells in the TME in human tumors. Bioinformatics analyses of the public patient datasets identified key tumor indications enriched in both adenosine and myeloid pathways. To further understand the spatial heterogeneity in the TME across tumors, we performed multiplex immunofluorescence on patient tumor microarrays to validate tumor types with a high prevalence of myeloid populations coupled with an active adenosine pathway, which will help guide future clinical study design. In summary, we demonstrate that ACTM-838 modulates the TME and is stable and safe in animal models. Additionally, our studies recommend the prioritization of certain tumor indications for treatment with ACTM-838 in the clinic. Citation Format: William Lu, Kyle Cron, Julie Janes, Leigh Berryman, Gurvinder Singh, Christopher Thanos, Akshata Udyavar. ACTM-838 safely and comprehensively re-activates the immunosuppressive TME by exploiting myeloid biology intrinsic in many cancers [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 736.
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Cáceres-Vásquez, Joaquín, Danilo H. Jara, Juan Costamagna, Fabián Martínez-Gómez, Carlos P. Silva, Luis Lemus, Eleonora Freire, Ricardo Baggio, Cristian Vera i Juan Guerrero. "Correction: Effect of non-covalent self-dimerization on the spectroscopic and electrochemical properties of mixed Cu(i) complexes". RSC Advances 13, nr 17 (2023): 11296. http://dx.doi.org/10.1039/d3ra90033a.

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Correction for ‘Effect of non-covalent self-dimerization on the spectroscopic and electrochemical properties of mixed Cu(i) complexes’ by Joaquín Cáceres-Vásquez et al., RSC Adv., 2023, 13, 825–838, https://doi.org/10.1039/D2RA05341A.
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Rozprawy doktorskie na temat "I-838"

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Tomaszewski, Tomasz. "Wykorzystanie minipróbek do wyznaczania trwałości i wytrzymałości zmęczeniowej". Rozprawa doktorska, Uniwersytet Technologiczno-Przyrodniczy w Bydgoszczy, 2015. http://dlibra.utp.edu.pl/Content/838.

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Praca dotyczy problematyki identyfikacji własności zmęczeniowej dla próbek o małych wymiarach. Badania eksperymentalne w zakresie zmęczenia wysokocyklowego przeprowadzono dla dwóch materiałów konstrukcyjnych (stop aluminium, miedź)
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Wallin, Pia. "Läroboken i ett sfi-perspektiv : om kvalitet i läroböcker i ämnet svenska för invandrare". Thesis, Linköping University, Department of Educational Science (IUV), 2000. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-838.

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Uppsatsen har till syfte att analysera och utvärderar fyra läroböcker i ämnet svenska för invandrare. Två problemformuleringar besvaras: vad bör en lärobok i sfi på nybörjarnivå för vuxna innehålla och vad är tecken på god kvalitet för en lärobok i sfi.

Analysen visar att en lärobok i sfi på nybörjarnivå för vuxna bör innehålla ett stoff som är korrekt, aktuellt och objektivt. Stoffet ska också vara anpassat till rätt stadium och ålder för målgruppen samt presenterat på ett språk som är begripligt för den som ska ta del av innehållet. Stoffet bör vidare spegla det mångkulturella samhället, bestå av olika typer av texter samt behandla olika språkliga element som grammatik, ordförråd och ordförklaringar, uttal och prosodi på ett varierat och autentiskt sätt.

Läroboken måste också ha ett pedagogiskt perspektiv som möjliggör varierade och individanpassade undervisningsmetoder, redovisningssätt och studiegångar. Den ska medvetandegöra eleverna om olika inlärningsstrategier och motivera dem till eget ansvarstagande för lärandet.

Illustrationerna i läroboken ska också utnyttja färger på ett riktigt sätt, samspela väl med texten och fylla en uppgift i sig själva och inte endast vara dekorativa.

Tecken på god kvalitet för en lärobok i sfi är att den är beskaffad på detta sätt, det vill säga innehåller rätt stoff, har ett godtagbart pedagogiskt perspektiv och godtagbara illustrationer.

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Ruiz, Grases Mònica. "Paper de la Reelina i la Netrina-1 en la migració neuronal al sistema nerviós central". Doctoral thesis, Universitat de Barcelona, 2001. http://hdl.handle.net/10803/838.

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L'objectiu general d'aquesta tesi ha estat el d'aprofundir en la funció de les molècules que fan possible que la migració neuronal es dugui a terme, permetent així un correcte desenvolupament del sistema nerviós central. Per assolir aquesta fita, ens hem centrar en les molècules de guia Reelina i Netrina-1, la proteïna adaptadora Dab1, i l'hormona tiroïdea, els mutants de les quals presenten greus alteraciones en el cervell degudes a migraciones neuronals aberrants en les primeres etapes de desenvolupament.
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Erlandsson, Jessica. "Gympa i förskolan? : En studie om pedagogers syn på motorik och rörelseglädje i förskolan". Thesis, Karlstad University, Faculty of Social and Life Sciences, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-838.

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The intention of the study is to investigate pedagogues understanding of physical activities in preschool. Should special activities be planned in order to stimulate children´s progress in motor skills? I also want to find out if pedagogues found the acitivities in preschool curriculum which says that the aim is to develop children´s body perception and teaching children how to care for their own health. I have interviewed seven pedagogues and focus of the question lied within motor skills and the joy of movement among preschool children. The result shows that pedagogues regard it to be important to stimulate motor activities and to encourage joy of movement in preschool. However the interviewed pedagogues believe that children can be supported in their development both through planned and more spontaneous activities. It is only a few of the pedagogues that make a connection between well developed motor skills in preschool children and the children´s future health.

Keywords: Preschool pedagogues, motor activity, planned activity and joy of movement

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Berglind, Lotta. "Användbarhetsexpertens roll som representant och medlare i systemutvecklingsprocesser". Thesis, University of Skövde, Department of Computer Science, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-838.

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I denna rapport talas det om användbarhetsexpertens roll som representant för användaren,medlare av termen användbarhet samt medlare mellan användaren och andra yrkesroller i en systemutvecklingsprocess. Denna roll har många gånger en tendens till att inte få tillräckligt med gehör av andra yrkesroller i utvecklingsprojekt. Det finns flera olika faktorer som kan bidra till detta. Vad som framkom i resultatet var en bekräftelse på att användbarhetsexpertens

roll är viktig i fråga om representering och medling. Vad gäller faktorn samarbete anser respondenterna att samarbetet för det mesta fungerar bra mellan dem och andra yrkesroller. Samarbete ses därmed inte som en faktor som påverkar gehöret för en användbarhetsexperts roll i systemutvecklingsprocesser. Respondenterna tycker däremot att de inte alltid får gehör för sin roll som användbarhetsexpert fast att de tycker att samarbetet med andra yrkesroller fungerar bra. En faktor som bidrar till

detta är den svårdefinierade termen användbarhet.

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Sara, Hammarin, Sjöholm Anna i Carlsson Evelina. "Revisionsplikten försvinner - en studie över vad kreditgivare i framtiden kommer att efterfråga för information vid kreditärenden". Thesis, Halmstad University, School of Business and Engineering (SET), 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-838.

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I mars 2005 publicerade Svenskt Näringsliv en rapport om revisionsplikten i små och medelstora aktiebolag. Rapporten slog fast att Sverige bör avskaffa revisionsplikten i små aktiebolag.

Med den här uppsatsen har vi utrett vilken slags information som kreditgivare kommer att använda vid kreditärenden för småföretag när revision blir frivillig. Syftet med uppsatsen är att ur kreditgivarnas synvinkel beskriva och analysera vad för slags information som kommer att bli aktuell vid framtida kreditärenden, när revision blir frivillig. Vi har även tagit reda på vad bankerna kan se för konsekvenser med att revisionsplikten avskaffas.

För att få klarhet i vår problemställning har vi genomfört en empirisk undersökning i form av personliga intervjuer med Sveriges fyra största banker (Petersson, 2006). Vidare har vi även använt tidigare undersökningar av bland annat Halling (2007) och Thorell & Norberg (2005).

Studien visade att bankerna även i fortsättningen kommer att efterfråga redovisningsinformation som ger den säkerhet som revision innebär. Informationen i årsredovisningen fungerar som en förtroendeskapande faktor för att säkerställa att företaget kan fullfölja sina förpliktelser gentemot banken. Ett borttagande av revisionsplikten kommer leda till att kvalitetsstämpeln försvinner vilket innebär att bankerna kommer efterfråga en utomstående parts bedömning för att säkra informationen i årsredovisningen.

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Gååse, Marie. "Jämställdhet i skolan : Jämställdhet och demokrati måste ständigt erövras på nytt (SOU:83, s. 59 f)". Thesis, Högskolan Dalarna, Pedagogiskt arbete, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:du-29382.

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Detta är en kvalitativ studie som undersöker pedagogers arbete med jämställdhetsuppdraget på en skola. Syftet med studien är att undersöka hur de definierar begreppet jämställdhet och hur de arbetar med jämställdhet i relation till eleverna och om de anser att arbetet är lyckat. För att få svar på dessa frågor har fyra pedagoger intervjuats som arbetar på en skola med elever från förskoleklass till sexan. Studien belyser även vilka resurser som finns för att genomföra uppdraget och vilka prioriteringar som pedagogerna gör. Resultatet visar att pedagogerna i brist på resurser, kompetens och pedagogisk ledning inte har möjlighet att prioritera jämställdhetsarbetet. De enskilda pedagogerna använder sig ibland av en medveten pedagogik med ett jämställdhetsperspektiv men det finns inget genomgående jämställdhetsarbete i verksamheten. Definitionen av jämställdhet är inte samstämmig bland pedagogerna och de är inte enade om deras jämställdhetsarbete är lyckat eller ej. Jag har i min studie kommit fram till att de intervjuade kvinnliga pedagogernas kunskap kring jämställdhet bygger mycket på "common sense", förgivet taganden som reproducerar könsmönstren istället för att motverka dessa. Kraven på flickorna är högre än på pojkarna och pojkarna tillåts att ta mer utrymme i klassrummet än flickorna.
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Elias, Therése. "En översyn av översynen : En studie av SOU 2015:83s förslag om utvidgad rätt att vidta stridsåtgärder i ljuset av lex Laval och EU-rätten". Thesis, Uppsala universitet, Juridiska institutionen, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-312855.

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The year of 2007 was indeed a year of turmoil for the Swedish labor law. This was the year of the preliminary ruling in the case “Laval un Partneri” (C-341/05), in which the ECJ ruled that the right to take collective action against foreign employers who post employees to work in Sweden as stated in Swedish labor law at the time constituted a disproportionate restriction on the freedom to provide services.   Due to the ruling of the ECJ, the Swedish legislature governing the right to take collective action toward these employers had to be modified. Changes were made in order to align the Swedish labour law with the EU-law, especially concerning the Posting of Workers Act. These amendments came to be referred to as “lex Laval”, and they constitute a restriction on the right to take collective action.   As a result of a heated public debate regarding the right to take collective action, lex Laval is now about to be amended. The purpose of the revision of the legislation is to, once again, extend the right to take collective action. This is motivated by a demand of improved possibilities to control the working conditions which the employers actually apply to the posted workers. This is said to be in line with the EU-law since the approval of the new Enforcement Directive (2014/67/EU) in 2014.     The main purpose of this essay is to give an account of the legislative changes made to the Swedish labor law in consequence of the Laval case as well as the expected changes to come, and to analyze these coming changes from an EU-law point of view. Will they constitute a disproportionate restriction on the freedom to provide services just like the legislation before the Laval case did? In addition, the essay will also give an account of the public debate regarding posting of workers, both on a Swedish national level and on an EU-level. In the light of the debate, the essay will also analyze the European Commission’s proposal of a new directive amending the existing Posted Workers directive (96/71/EC) in relation to the latest proposed change of lex Laval.
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Hultsch, Christina. "Die Anfechtung der Erbschaftsausschlagung im deutschen, US-amerikanischen und dänischen Insolvenzverfahren : ein Beitrag zu [section] 83 I InsO aus rechtsvergleichender und effizienztheoretischer Sicht /". Dresden : TUD-Press, 2006. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=015616975&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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Korth, Hans-Otto. "Das älteste Gesangbuch Schlesiens - Breslau 1525, herausgegeben und mit einem Kommentar versehen von Anna Mańko-Matysiak / Najstarszy šlaski špiewnik košcielny - Wrocław 1525, Redakcja i komentarz Anna Mańko-Matysiak, Wrocław 2004. ISBN: 83-921013-1-6. (CD; = e-Biblioteka Historyczna 1) [Rezension]". Arbeitsgemeinschaft für die Musikgeschichte in Mittel- und Osteuropa an der Universität Leipzig, Leipzig, 2005. https://ul.qucosa.de/id/qucosa%3A15980.

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Książki na temat "I-838"

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Забаштанська, Н., red. Українська мова та література: I частина: За новою редакцією правопису. Київ, Україна: Грамота, 2020.

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Slovat︠s︡kiĭ, Roman. Khramy i monastyri Kolomenskoi zemli: K 835-letiiu Kolomny. Kolomna: Liga, 2012.

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Fīrūz, Zanūzī Jalālī, red. Qiṣṣah-ʼi 83: Majmūʻah-i dāstān. Tihrān: Sūrah-i MIhr, 2004.

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Kemppainen, Eeva-Kaisa. Väestön koulutustaso Helsingissä 1981-83 =: Befolkningens utbildningsnivå i Helsingfors 1981-83. Helsinki: TILK, 1985.

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Ier, Bibliothèque royale Albert. Het Geraardsbergse handschrift: Hs. Brussel, Koninklijke Bibliotheek Albert I, 837-845. Hilversum [Netherlands]: Verloren, 1994.

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Knudsen, Jørgen. Georg Brandes: I modsigelsernes tegn Berlin 1877-83. København: Gyldendal, 1988.

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Farzām, Ḥamīd. Taḥqīq dar aḥvāl va naqd-i ās̲ār va āfkār-i Shāh Niʻmat Allāh Valī: 731-834 H.Q. Wyd. 8. Tihrān: Surūsh, 1995.

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1932-, Futagawa Yukio, i Ashraf Kazi Khaleed, red. Louis I. Kahn: National capital of Bangladesh, 1962-83. Tokyo: A.D.A. Edita, 1994.

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Regulski, Wojciech, i Bartłomiej Bałut. 83 lata Pracowni Liternictwa i Typografii w ASP w Krakowie. Kraków: Akademia Sztuk Pięknych im. Jana Matejki w Krakowie, 2012.

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Kristoffersen, Terje. De tause heltene: 830 S : i livsfarlig oppdrag for norsk etterretning og sikringstjenese 1940-45. Porsgrunn: Norgesforl., 2009.

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Części książek na temat "I-838"

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Elste, Martin. "Die sechs Partiten der Clavierübung I BWV 825–830". W Meilensteine der Bach-Interpretation 1750–2000, 366–71. Stuttgart: J.B. Metzler, 2000. http://dx.doi.org/10.1007/978-3-476-03792-3_38.

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Screen, Elina. "Lothar I in Italy, 834–40: Charters and Authority". W Problems and Possibilities of Early Medieval Charters, 231–52. Turnhout: Brepols Publishers, 2013. http://dx.doi.org/10.1484/m.imr-eb.1.101685.

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Tomei, Paolo. "Writing, textuality, politics in the Lucca of Bishops Berengar and Ambrose (837-852)". W Reti Medievali E-Book, 157–80. Florence: Firenze University Press, 2022. http://dx.doi.org/10.36253/978-88-5518-623-0.09.

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The article consists of two intertwined sections. In the first, I intend to reconstruct the processes of political and social transformation that took place in Lucca under the actions of Bishops Berengar (837-843) and Ambrose (843-852): foreigners appointed in succession by the Court. In order to do this, I will take the viewpoint offered by the numerous private charters preserved in the Archivio Storico Diocesano of Lucca. Secondly, I will present the first results of a study on the manuscripts of the same period preserved there – an heritage not yet fully explored and appreciated. I will focus in particular on the most-recently entered text in ms 490: the so-called Dicta Gelasii papae. It was written in a Carolingian hand that Armando Petrucci has compared to that of Bishop Berengar. The text constitutes an exceptional insight into the turmoil that animated the sacred palace after the «penitential reform» of 813, and which spread throughout the Empire within a general movement of correctio.
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De Francesco, Siria. "Sulle tracce della Querelle du Roman de la Rose. Alcune osservazioni su un anonimo explicit del MS Ludwig XV 7 (83.MR.177), J. Paul Getty Museum, Los Angeles". W Lectio, 91–116. Turnhout, Belgium: Brepols Publishers, 2023. http://dx.doi.org/10.1484/m.lectio-eb.5.135388.

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Morales, Yonis, i Rolando Grajeda. "Virulence genes of new population of coffee rust (Hemileia vastatrix) affecting coffee variety 'Lempira', in Honduras; resistant and susceptible varieties." W Mutation breeding, genetic diversity and crop adaptation to climate change, 338–43. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789249095.0035.

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Abstract The coffee variety 'Lempira', released in Honduras in 1998, was classified 100% resistant to races I and II of coffee rust identified by Portugal's Centre for Research into Coffee Rusts (Centro de Investigação das Ferrugens do Cafeeiro) (CIFC) in 1997. However, since 2007, the disease has been reported in seed foundation plots and producer farms, the most recent epidemic report being in April 2016 in Vegas de Jalan, Juticalpa Olancho, affecting 210 ha. Since this variety constitutes 45% of the cultivated area under coffee in the country, there is a need to identify the virulence genes of the new strain and to determine the resistance and susceptibility of other cultivated varieties. For these purposes, mass samples of rust were inoculated on leaf discs of the differential clones 1343/269, 110/5, 147/1, 152/3, 33/1, 419/20, 832/1 and 832/2, together with 87/1, 1006/10, 420/10 and 420/2 from the Federal University of Vicosa, as well as on the two main cultivated resistant varieties ('Parainema' and 'IHCAFE- 90'), and seven promising genotypes, under controlled temperature conditions and relative humidity. After 20-60 days of inoculation, seven virulence genes were identified (v1, v2, v4, v5, v6, v7, v9), of which v1, v4, v6, v7 and v9 had not been reported in Honduras previously. It is inferred that this rust population arose by recombination of race v5 with v6, v7 or v9. Races with 3, 4, 5, 6 or 7 virulence determinants were identified as the most complex and aggressive strains described but they lacked the v3 and v8 determinants. In addition, it was found that 'Parainema', 'H27', 'T5296-170', 'Central American', 'Pacamara yellow' and 'Anacafe-14' are resistant because they possess the SH8 gene, absent from 'Lempira'. 'IHCAFE-90' and 'Obatá' showed 20% susceptibility, and 'Ruiru 11' was susceptible. The results reveal the diversity of rust virulence genes in Honduras and emphasize the importance of the SH3 and SH8 genes as sources of resistance.
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René, Miloš. "Investigation of Accessory Minerals from the Blatná Granodiorite Suite, Bohemian Massif, Czech Republic". W Mineralogy [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.102628.

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The Central Bohemian magmatic complex belongs to the Central European Variscan belt. The granitic rocks of this plutonic complex are formed by several suites of granites, granodiorites, and tonalites, together with small bodies of gabbros, gabbro diorites, and diorites. The granodiorites of the Blatná suite are high-K, calc-alkaline to shoshonitic, and metaluminous to slightly peraluminous granitic rocks. Compared to the common I-type granites, granodiorites of the Blatná suite are enriched in Mg (1.0–3.4 wt.% MgO), Ba (838–2560 ppm), Sr. (257–506 ppm), and Zr (81–236 ppm). For granodiorites of the Blatná suite is assemblage of apatite, zircon, titanite, and allanite significant. Zircon contains low Hf concentrations (1.1–1.7 wt.% HfO2). The composition of titanite ranges from 83 to 92 mol.% titanite end-member. Allanite is relatively Al-poor and displays Feox. ratio 0.2–0.5.
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"χωρέω". W P[i] - O[mega], 1570. De Gruyter, 2015. http://dx.doi.org/10.1515/9783110802184-838.

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Radcliffe, Philip. "1838–44". W Mendelssohn, 35–44. Oxford University PressOxford, 2001. http://dx.doi.org/10.1093/oso/9780198164937.003.0005.

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Abstract The next few years were spent for the most part at Leipzig and involved much musical activity. The concerts flourished; there was an enterprising historical series, including works by composers as unfamiliar as Naumann, Righini and Vogler; there were performances of Beethoven’s little-known cantata Der glorreiche Augenblick and of Felix’s own setting of Psalm XLII. Much music was written in I 838, including the Cello Sonata in B flat, op. 45, the String Quartets in E flat and D from op. 44 and the setting of Psalm XCV. On 7 February 1838 his first son, Karl Wolfgang Paul, was born; Cecile was seriously ill and caused Felix acute anxiety. In June he conducted the Lower Rhine Festival at Cologne, and the rest of the summer was spent very happily in Berlin. This was Cecile’s first meeting with the rest of the family.
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Skotnicki, Krzysztof, i Katarzyna Wlaźlak. "Wprowadzenie". W Regiony w prawie i praktyce. Polska - Ukraina, 7–9. Wydawnictwo Uniwersytetu Łódzkiego, 2015. http://dx.doi.org/10.18778/7969-838-7.01.

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Kasiński, Michał. "Kształtowanie pozycji ustrojowej województwa jako regionu samorządowego". W Regiony w prawie i praktyce. Polska - Ukraina, 11–35. Wydawnictwo Uniwersytetu Łódzkiego, 2015. http://dx.doi.org/10.18778/7969-838-7.02.

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Streszczenia konferencji na temat "I-838"

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Jorgensen, Kirsten, Chi-Fang Wu, Clare Meernik, Roni Nitecki, Alexander Melamed i Jose Alejandro Rauh-Hain. "2022-RA-838-ESGO All-cause and cancer-specific mortality after fertility-sparing surgery for stage I epithelial ovarian cancer". W ESGO 2022 Congress. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/ijgc-2022-esgo.375.

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Veiga, Dayana Pereira, i Cristiane Fernandes de Freitas Tavares. "PERFIL HEMATOLÓGICO DOS IDOSOS ACOMETIDOS PELO COVID-19 NA CIDADE DE FRANCA-SP". W I Congresso Brasileiro de Bioquímica Humana On-line. Revista Multidisciplinar em Saúde, 2021. http://dx.doi.org/10.51161/rems/838.

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Introdução: Covid-19 é uma doença altamente contagiosa provocada pelo coronavírus denominado SARS-CoV2, síndrome respiratória aguda grave. Em 2020, a Covid-19 foi caracterizada pela Organização Mundial de Saúde (OMS) como uma pandemia, atingindo todo o mundo, porém acometendo gravemente os idosos. Estes são mencionados como o grupo mais vulnerável uma vez que possuem doenças crônicas como hipertensão, diabetes, cardiopatias, doenças respiratórias e renais. Objetivo: Correlacionar o perfil hematológico dos pacientes idosos da cidade de Franca-SP, acometidos pelo Covid-19, que apresentaram alguma comorbidade e vieram a óbito. Material e métodos: Para o levantamento de estudo foi realizado uma busca de dados na fonte da Vigilância Epidemiológica Municipal de Franca-SP. Resultados: O quadro clínico-laboratorial da Covid-19 teve relação com as alterações hematológicas e da coagulação, capazes de levar ao dano tecidual e morte. Dados laboratoriais relataram uma variação na contagem total de leucócitos, diminuição da hemoglobina, aumento da taxa de hemossedimentação de eritrócitos, linfopenia com depleção de linfócitos CD4 e CD8 e alteração plaquetária. Os pacientes, na faixa etária de 70 aos 89 anos apresentaram algum tipo de comorbidade relacionadas com alterações hematológicas, ocorrendo o óbito em 78,2% no mês de dezembro, 65,7% em janeiro e 76,8% em fevereiro de 2020. Conclusão: Esses dados evidenciam uma alta taxa de mortalidade em pacientes idosos e que apresentavam algum tipo de comorbidade. A análise laboratorial foi fundamental para o maior conhecimento da doença, na definição e avaliação do diagnóstico dos pacientes com Covid-19. Para a Vigilância Epidemiológica é crucial coletar amostras clínicas para detecção do vírus e para um protocolo melhor de tratamento.
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Zhang, Yue, i Arti Ramesh. "Learning Interpretable Relational Structures of Hinge-loss Markov Random Fields". W Twenty-Eighth International Joint Conference on Artificial Intelligence {IJCAI-19}. California: International Joint Conferences on Artificial Intelligence Organization, 2019. http://dx.doi.org/10.24963/ijcai.2019/838.

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Statistical relational models such as Markov logic networks (MLNs) and hinge-loss Markov random fields (HL-MRFs) are specified using templated weighted first-order logic clauses, leading to the creation of complex, yet easy to encode models that effectively combine uncertainty and logic. Learning the structure of these models from data reduces the human effort of identifying the right structures. In this work, we present an asynchronous deep reinforcement learning algorithm to automatically learn HL-MRF clause structures. Our algorithm possesses the ability to learn semantically meaningful structures that appeal to human intuition and understanding, while simultaneously being able to learn structures from data, thus learning structures that have both the desirable qualities of interpretability and good prediction performance. The asynchronous nature of our algorithm further provides the ability to learn diverse structures via exploration, while remaining scalable. We demonstrate the ability of the models to learn semantically meaningful structures that also achieve better prediction performance when compared with a greedy search algorithm, a path-based algorithm, and manually defined clauses on two computational social science applications: i) modeling recovery in alcohol use disorder, and ii) detecting bullying.
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Shterengas, L., R. Liang, T. Hosoda, G. Kipshidze, G. Belenky, S. S. Bowman i R. L. Tober. "Type-I QW cascade diode lasers with 830 mW of CW power at 3 μm". W SPIE OPTO, redaktorzy Alexey A. Belyanin i Peter M. Smowton. SPIE, 2015. http://dx.doi.org/10.1117/12.2076631.

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Георгиев, Павел. "Princeps Avarum and Cani Zauci in Aachen in the autumn of 811. Towards the Bulgarian-Frankish relations under the rules Krum (802?–814) and Omurtag (814–831)". W Hadak útján. A népvándorláskor kutatóinak XXIX. konferenciája. Budapest, 2019. november 15–16. 29th. Bölcsészettudományi Kutatóközpont Magyar Őstörténeti Kutatócsoport, 2022. http://dx.doi.org/10.55722/arpad.kiad.2021.4.1_10.

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The author offers new possibilities for interpretation of Frankish, domestic and Byzantine sources regarding the Bulgarian political control over territories of Avar Khaganate, destroyed by Charlemagne. The main focus is placed on the certificate of embassy led by Princeрs Avarum and Canizauci in Aachen in November 811. Coordinating it with Bulgarian and Byzantine sources, leads to the following conclusions. 1. It is likely that the diplomatic mission to Charlemagne in 811, involving representatives of the Avar com­munity, led by its Tudun and Slavic tribal princes, was led by the Bulgarian prince – Omurtag, the younger brother of the ruler Krum (802? – 814), in his capacity as prince (princeps) and ombritag. i. e. Avars hegem­on, in the northwestern borders after 803 and „Khan’s beloved younger brother” (khani sev`ingi or khani sev(inč) ingi). In Aachen, he introduced himself as a cani zautzi, that is, with his post of „Khan’s envoy”. 2. The khanas uvigi Omurtag (814–831) missions to Emperor Louis in 824 and 825–826 appear to have also been led by a member of the ruling family in Plisk oba (Pliska), maybe from his second son – Zvinitsa/Zvinichis. They also appear to have had a representative/s of settlers between 813 and 837 in Trans­Danubian Bulgaria (probably in the Lower Tisza region) of Bulgarian captives of Eastern Thrace of Armenian origin. One of their leaders in 837 was named Tzantzès, and his son, Stilian, and his descendants gained fame in Byzantium under the surname Ζαούτζης, Ζαούτζας. It coincides exactly with the pro­Bulgarian official title (position) zautzi (tzautci), (=chaush) and probably derived from it. On this basis, we conclude that Τζάντζην (Öан¤·þ воеводэ) was performing the carrier of messages or emissary functions of the Bulgarian state before 837. 3. The considered evidence, facts and circumstances surrounding the Bulgarian diplomatic missions of 811, 824 and 825/6 provide new testifies for the Bulgarian state’s control over the south-eastern parts of the Avar Khaganate after its collapse in the period 791–803. They have a contribution to clarify important aspects of the Bulgarian state’s relations with the East Frankish Kingdom, as well as with the local population of Avars, Bulgarians and Slavs there.
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Mahambetov, E. M., Roman Voroshilin, O. I. Kalugina, Yu A. Kostel'ceva, S. S. Golubeva i V. V. Maklyuk. "DEVELOPMENT AND RESEARCH OF TECHNOLOGICAL PARAMETERS OF THE VACUUM DRYER FOR THE PRODUCTION OF DRY GELATIN". W I International Congress “The Latest Achievements of Medicine, Healthcare, and Health-Saving Technologies”. Kemerovo State University, 2023. http://dx.doi.org/10.21603/-i-ic-83.

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Purpose: to develop a prototype of a laboratory vacuum dryer, to select parameters for obtaining dry gelatin. To conduct research on the indications of the quality of the obtained dry gelatin in a vacuum dryer.
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Santiskulvong, Chintda, Carol Eng, David T. Wang, Wing Y. Lung, Sara Zabih, Richard C. Koya i Oliver Dorigo. "Abstract 836: Insulin-like growth factor-I receptor (IGF-IR) dowregulation in cisplatin-resistant human ovarian cancer cells". W Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-836.

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Bašan, Lorena. "UPOTREBLJAVAJU LI HOTELI WEB-STRANICE ZA KOMUNIKACIJU ODRŽIVOSTI DESTINACIJE?" W Hotelska kuća 2022. University of Rijeka, Faculty of Tourism and Hospitality Management, 2022. http://dx.doi.org/10.20867/hk.1.1.

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Svrha – Svrha je ovog rada utvrditi uporabu okolišnih, društveno-kulturnih i ekonomskih atributa na web-stranicama hotela za komunikaciju održivosti destinacije, odnosno informiranje o održivosti destinacije te motiviranje i uključivanje dionika u destinaciji u primjenu održivosti. Metode – Empirijsko istraživanje provedeno je u periodu od ožujka do lipnja 2018. godine. U okviru istraživanja primijenjena je analiza sadržaja web-stranica hotela s 4 i 5 zvjezdica u Republici Hrvatskoj. Istraživanjem je obuhvaćeno ukupno 236 web-stranica hotela ili 70,2 % svih hotela s 4 i 5 zvjezdica u Republici Hrvatskoj, odnosno 37 web-stranica hotela s 5 zvjezdica (83,8 %) i 205 web-stranica hotela s 4 zvjezdice (68,6 %). Analizirane dimenzije odnose se na okolišne, društveno-kulturne i ekonomske atribute značajne u kontekstu informiranja te uključivanja i motiviranja dionika destinacije s ciljem efikasnije i efektivnije komunikacije održivosti destinacije putem web-stranica hotela. Korišten je Pearsonov koeficijent korelacije za utvrđivanje statističkog značaja povezanosti održivih atributa web-stranice hotela s ukupnim informiranjem te ukupnim uključivanjem i motiviranjem dionika za održivost destinacije. U analizi utjecaja atributa održivosti korištenih na web-stranicama hotela na ukupnu informiranost o održivosti destinacije te na ukupno motiviranje i uključivanje dionika u primjenu održivosti, korištena je višestruka linearna regresijska analiza. Zaključci – Rezultati istraživanja provedene analize sadržaja web-stranica hrvatskih hotela ukazuju na to da vrlo mali udio hotela koristi svoje web-stranice za informiranje o održivosti destinacije te za uključivanje i motiviranje dionika za primjenu održivosti. Najveći udio hotela, u kontekstu informiranja javnosti o održivosti destinacije, putem svojih web-stranica pruža informacije o važnosti turizma u destinaciji (ekonomski atribut), doprinosu turizma poboljšavanju života lokalne zajednice (društveno-kulturni atribut) i prezentira karte osjetljivih područja za kulturne i prirodne resurse (okolišni atribut). S ciljem motiviranja i uključivanja dionika za primjenu održivosti, hoteli u najvećoj mjeri upotrebljavaju u okviru svojih web-stranica forume i blogove za povezivanje dionika (društveno-kulturni atribut), izravne rezervacije (ekonomski atribut) i sustav certifikacije (okolišni atribut). Dobivene vrijednosti Pearsonovog koeficijenta korelacije ukazuju na slabu do umjereno pozitivnu i značajnu povezanost analiziranih atributa web-stranica hotela s ukupnim informiranjem te ukupnim uključivanjem i motiviranjem dionika za održivost destinacije. Rezultatima višestruke linearne regresijske analize potvrđen je pozitivan i značajan utjecaj svih atributa održivosti kako na informiranost o održivosti destinacije, tako i na motiviranje i uključivanje dionika u primjenu održivosti. Doprinos – Rezultati empirijskog istraživanja predstavljaju značajan doprinos ukazujući na nedovoljnu iskorištenost potencijala web-stranica hotela kako u kontekstu informiranja o održivosti destinacije tako i za uključivanje i motiviranje dionika za održivost. U primjeni atributa održivosti na web-stranicama hotela postoji neusklađenost između intenziteta korištenja atributa kod svih dimenzija održivosti i njihove povezanosti s ukupnom informiranošću o održivosti destinacija, kao i s ukupnim motiviranjem i uključivanjem dionika u primjenu održivosti. Stoga je aplikativni doprinos ovog rada vidljiv iz preporuka hotelskom menadžmentu za korištenje pojedinih atributa u komunikaciji održivosti, s ciljem postizanja uravnoteženosti između okolišnih, društvenokulturnih i ekonomskih atributa prilikom komunikacije održivosti hotela putem web-stranica.
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Huh, Jin, i Chun-Taek Rim. "KAIST Wireless Electric Vehicles - OLEV". W 1st International Electric Vehicle Technology Conference. 10-2 Gobancho, Chiyoda-ku, Tokyo, Japan: Society of Automotive Engineers of Japan, 2011. http://dx.doi.org/10.4271/2011-39-7263.

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<div class="section abstract"><div class="htmlview paragraph">In order to minimize the greenhouse effect due to the emission of CO<sub>2</sub>, automobile manufactures have been developing battery-powered plug-in automobiles with re-chargeable Lithium Polymer batteries. However, these pure electric vehicles (EVs) are not welcomed in the market because the Lithium batteries are heavy and still expensive with limited rechargeable cycles. Furthermore, charging time and relatively short driving range obstruct the commercialization of EVs. To solve the problems, KAIST proposed four generations of On-Line Electric Vehicles (OLEVs), a sort of roadway wireless powered EVs. This paper summarizes the progress of the OLEV developments. Four generations of OLEV were demonstrated for different underground electric power rails and pick-ups. The air-gap of the 1st generation OLEV car is 1 <i>cm</i> and the input to output power efficiency is 80 % with 3 <i>kW</i> output power. The ultra slim U-type mono rail applied to the 2nd generation OLEV bus gives 52 <i>kW</i> output power with 72 % efficiency at 17 <i>cm</i> air-gap. The ultra slim W-type dual rail applied to the 3rd generation OLEV sports utility vehicle delivers 15 <i>kW</i>/pick-up power with 71 % efficiency at 17 <i>cm</i> air- gap, which has recently been improved to 83 % at 20 <i>cm</i> air-gap for an OLEV bus, and 74 % efficiency at 12 <i>cm</i> air-gap for an OLEV train, respectively. The 4th generation of OLEV bus is under development, which has very narrow I-type underground power rails and compact high power pick-ups with drastically reduced electro-magnetic field (EMF), lower construction cost, small installation time, and enhanced lateral displacement. Throughout the development of OLEV, it has shown that low cost EV without high reliance on batteries with sufficiently high power capacity, efficiency, and air-gap is possible, which were the major obstacles of the roadway powered EV for practical applications.</div></div>
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De Backer, Hugo, Eric P. Visser, Dirk De Muer i Daan P. J. Swart. "To what extent can routine ozone lidar measurements provide a representative data set in view of the restricted operation time due to cloud cover?" W Optical Remote Sensing of the Atmosphere. Washington, D.C.: Optica Publishing Group, 1993. http://dx.doi.org/10.1364/orsa.1993.pd.5.

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For a proper understanding of long term trends in atmospheric ozone concentrations, the availability of high quality data sets is of great importance. At present, total ozone column densities are routinely measured by the ground based Dobson, Brewer and M-83/124 filter ozonometer networks, as well as by satellite based instruments such as the Total Ozone Mapping Spectrometer (TOMS). Vertical concentration profiles are obtained by ground based Umkehr methods, balloon borne electrochemical ozone sondes and by satellite based limb path atmospheric extinction measurements, such as the Stratospheric Aerosol and Gas Experiments (SAGE I/II).
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Raporty organizacyjne na temat "I-838"

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Palmer, E. Phase I Focused Corrective Measures Study/Feasibility Study for the L-Area Oil and Chemical Basin (904-83G). Office of Scientific and Technical Information (OSTI), luty 1997. http://dx.doi.org/10.2172/630852.

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Jacobson, Birgitta, Håkan Wickström, Jennie Strömquist i John Persson. Ålmärkningsprojekt i sjön Ymsen : sammanställning av data från 1998–2022. Department of Aquatic Resources, Swedish University of Agricultural Sciences, 2024. http://dx.doi.org/10.54612/a.1bbflv35va.

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Denna rapport sammanställer information om märkningsprojekt med ål (Anguilla anguilla) utförda i sjön Ymsen. Märkningsexperimenten utfördes åren 1998–2002 samt 2012. Data över återfångster samlas in kontinuerligt, en insamling som pågår än idag (år 2023). Denna rapport innehåller data insamlad fram till och med år 2022. Syftet med rapporten är både att sammanfatta vad som har gjorts och att redogöra för vilka data som finns tillgängliga för framtida projekt. Följande märkningsprojekt har utförts i sjön: • År 1998 utfördes en mindre inledande testmärkning med PIT-tags på ålyngel, 190 märkta ålar sattes ut. • År 1999 utfördes ytterligare en testmärkning med PIT-tags, denna gång märktes 83 gulålar. • År 1999–2002 utfördes märkningsexperiment för att undersöka om strontiummärkning (Sr) fungerar för att skilja utsatt från naturligt förekommande ål. Totalt sattes 17 768 Sr-märkta ålar ut, varav 2 627 även var märkta med PIT-tags (PIT-tags användes år 1999 och 2000). Av de som både var Sr och PIT-tag märkta så har 334 återfångats (till och med 2022) och resultaten visade att strontium fungerade bra för att märka ål. • År 2004 undersökte man skarvens påverkan som predator på ål genom att söka efter PIT-tags (från märkningarna som utfördes 1999 och 2000) i en skarvkoloni. Totalt 30 PIT-tag märken återfanns i skarvkolonin. • År 2012 utfördes ett märkningsexperiment där 118 gulålar märktes med PIT-tags och Carlinmärken för att undersöka om förlust av Carlinmärken förekom. Av de 65 ålar som återfångats (till och med 2016) hade en förlorat sitt Carlinmärke. Data över utsättningar och återfångster finns lagrade på Sötvattenslaboratoriet server, och/eller i databasen ”Sötebasen” (som hanteras av Sveriges lantbruksuniversitet, institutionen för akvatiska resurser, SLU Aqua)
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Stepanova, Y. V. PINS IN THE COSTUME OF THE POPULATION OF THE UPPER VOLGA OF THE 11TH –17TH CENTURIES. In: Zhenskaya traditsionnaya kul'tura i kostum v epokhu srednecekovya i novoe vremya. Vol. 4. Tver, Tver State University, 2022. P. 72-83. DOI СODE, 2022. http://dx.doi.org/10.18411/doicode-2022.020.

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Dohaney, J., J. M. R. Joseph i G. D. M. Andrews. Interactive bibliography and database for the Chilcotin Group basalts (NTS 82E, L, M; 83D; 92H, I, J, O, P; 93A, B, C, F, G, J, K, L), south-central British Columbia. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2010. http://dx.doi.org/10.4095/261828.

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Galvin, Jeff, i Sarah Strudd. Vegetation inventory, mapping, and characterization report, Saguaro National Park: Volume II, association summaries. Redaktor Alice Wondrak Biel. National Park Service, marzec 2021. http://dx.doi.org/10.36967/nrr-2284793.

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The Sonoran Desert Network (SODN) conducted a vegetation mapping and characterization effort at the two districts of Saguaro National Park from 2010 to 2018. This project was completed under the National Park Service (NPS) Vegetation Mapping Inventory, which aims to complete baseline mapping and classification inventories at more than 270 NPS units. The vegetation map data were collected to provide park managers with a digital map product that meets national standards of spatial and thematic accuracy, while also placing the vegetation into a regional and national context. A total of 97 distinct vegetation communities were described: 83 exclusively at the Rincon Mountain District, 9 exclusively at the Tucson Mountain District, and 5 occurring in both districts. These communities ranged from low-elevation creosote (Larrea tridentata) shrub-lands spanning broad alluvial fans to mountaintop Douglas fir (Pseudotsuga menziesii) forests on the slopes of Rincon Peak. All 97 communities were described at the association level, each with detailed narratives including lists of species found in each association, their abundance, landscape features, and overall community structural characteristics. Only 15 of the 97 vegetation types were existing “accepted” types within the National Vegetation Classification (NVC). The others are newly described and specific to Saguaro National Park (and will be proposed for formal status within the NVC). This document is Volume II of three volumes comprising the Saguaro National Park Vegetation Mapping Inventory. This volume provides two-page summaries of the 97 associations identified and mapped during the project, and detailed in Volume I. Summaries are presented by district, starting with the Tucson Mountain District. These summaries are abridged versions of the full association descriptions found in Volume III.
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Galvin, Jeff, i Sarah Studd. Vegetation inventory, mapping, and characterization report, Saguaro National Park: Volume III, type descriptions. Redaktor Alice Wondrak Biel. National Park Service, marzec 2021. http://dx.doi.org/10.36967/nrr-2284802.

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The Sonoran Desert Network (SODN) conducted a vegetation mapping and characterization effort at the two districts of Saguaro National Park from 2010 to 2018. This project was completed under the National Park Service (NPS) Vegetation Mapping Inventory, which aims to complete baseline mapping and classification inventories at more than 270 NPS units. The vegetation map data were collected to provide park managers with a digital map product that meets national standards of spatial and thematic accuracy, while also placing the vegetation into a regional and national context. A total of 97 distinct vegetation communities were described: 83 exclusively at the Rincon Mountain District, 9 exclusively at the Tucson Mountain District, and 5 occurring in both districts. These communities ranged from low-elevation creosote (Larrea tridentata) shrub-lands spanning broad alluvial fans to mountaintop Douglas fir (Pseudotsuga menziesii) forests on the slopes of Rincon Peak. All 97 communities were described at the association level, each with detailed narratives including lists of species found in each association, their abundance, landscape features, and overall community structural characteristics. Only 15 of the 97 vegetation types were existing “accepted” types within the NVC. The others are newly de-scribed and specific to Saguaro National Park (and will be proposed for formal status within the NVC). This document is Volume III of three volumes comprising the Saguaro National Park Vegetation Mapping Inventory. This volume provides full type descriptions of the 97 associations identified and mapped during the project, and detailed in Volume I. Volume II provides abridged versions of these full descriptions, briefly describing the floristic and structural characteristics of the vegetation and showing representative photos of associations, their distribution, and an example of the satellite imagery for one polygon.
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Hajarizadeh, Behzad, Jennifer MacLachlan, Benjamin Cowie i Gregory J. Dore. Population-level interventions to improve the health outcomes of people living with hepatitis B: an Evidence Check brokered by the Sax Institute for the NSW Ministry of Health, 2022. The Sax Institute, sierpień 2022. http://dx.doi.org/10.57022/pxwj3682.

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Background An estimated 292 million people are living with chronic hepatitis B virus (HBV) infection globally, including 223,000 people in Australia. HBV diagnosis and linkage of people living with HBV to clinical care is suboptimal in Australia, with 27% of people living with HBV undiagnosed and 77% not receiving regular HBV clinical care. This systematic review aimed to characterize population-level interventions implemented to enhance all components of HBV care cascade and analyse the effectiveness of interventions. Review questions Question 1: What population-level interventions, programs or policy approaches have been shown to be effective in reducing the incidence of hepatitis B; and that may not yet be fully rolled out or evaluated in Australia demonstrate early effectiveness, or promise, in reducing the incidence of hepatitis B? Question 2: What population-level interventions and/or programs are effective at reducing disease burden for people in the community with hepatitis B? Methods Four bibliographic databases and 21 grey literature sources were searched. Studies were eligible for inclusion if the study population included people with or at risk of chronic HBV, and the study conducted a population-level interventions to decrease HBV incidence or disease burden or to enhance any components of HBV care cascade (i.e., diagnosis, linkage to care, treatment initiation, adherence to clinical care), or HBV vaccination coverage. Studies published in the past 10 years (since January 2012), with or without comparison groups were eligible for inclusion. Studies conducting an HBV screening intervention were eligible if they reported proportion of people participating in screening, proportion of newly diagnosed HBV (participant was unaware of their HBV status), proportion of people received HBV vaccination following screening, or proportion of participants diagnosed with chronic HBV infection who were linked to HBV clinical care. Studies were excluded if study population was less than 20 participants, intervention included a pharmaceutical intervention or a hospital-based intervention, or study was implemented in limited clinical services. The records were initially screened by title and abstract. The full texts of potentially eligible records were reviewed, and eligible studies were selected for inclusion. For each study included in analysis, the study outcome and corresponding 95% confidence intervals (95%CIs) were calculated. For studies including a comparison group, odds ratio (OR) and corresponding 95%CIs were calculated. Random effect meta-analysis models were used to calculate the pooled study outcome estimates. Stratified analyses were conducted by study setting, study population, and intervention-specific characteristics. Key findings A total of 61 studies were included in the analysis. A large majority of studies (study n=48, 79%) included single-arm studies with no concurrent control, with seven (12%) randomised controlled trials, and six (10%) non-randomised controlled studies. A total of 109 interventions were evaluated in 61 included studies. On-site or outreach HBV screening and linkage to HBV clinical care coordination were the most frequent interventions, conducted in 27 and 26 studies, respectively. Question 1 We found no studies reporting HBV incidence as the study outcome. One study conducted in remote area demonstrated that an intervention including education of pregnant women and training village health volunteers enhanced coverage of HBV birth dose vaccination (93% post-intervention, vs. 81% pre-intervention), but no data of HBV incidence among infants were reported. Question 2 Study outcomes most relevant to the HBV burden for people in the community with HBV included, HBV diagnosis, linkage to HBV care, and HBV vaccination coverage. Among randomised controlled trials aimed at enhancing HBV screening, a meta-analysis was conducted including three studies which implemented an intervention including community face-to-face education focused on HBV and/or liver cancer among migrants from high HBV prevalence areas. This analysis demonstrated a significantly higher HBV testing uptake in intervention groups with the likelihood of HBV testing 3.6 times higher among those participating in education programs compared to the control groups (OR: 3.62, 95% CI 2.72, 4.88). In another analysis, including 25 studies evaluating an intervention to enhance HBV screening, a pooled estimate of 66% of participants received HBV testing following the study intervention (95%CI: 58-75%), with high heterogeneity across studies (range: 17-98%; I-square: 99.9%). A stratified analysis by HBV screening strategy demonstrated that in the studies providing participants with on-site HBV testing, the proportion receiving HBV testing (80%, 95%CI: 72-87%) was significantly higher compared to the studies referring participants to an external site for HBV testing (54%, 95%CI: 37-71%). In the studies implementing an intervention to enhance linkage of people diagnosed with HBV infection to clinical care, the interventions included different components and varied across studies. The most common component was post-test counselling followed by assistance with scheduling clinical appointments, conducted in 52% and 38% of the studies, respectively. In meta-analysis, a pooled estimate of 73% of people with HBV infection were linked to HBV clinical care (95%CI: 64-81%), with high heterogeneity across studies (range: 28-100%; I-square: 99.2%). A stratified analysis by study population demonstrated that in the studies among general population in high prevalence countries, 94% of people (95%CI: 88-100%) who received the study intervention were linked to care, significantly higher than 72% (95%CI: 61-83%) in studies among migrants from high prevalence area living in a country with low prevalence. In 19 studies, HBV vaccination uptake was assessed after an intervention, among which one study assessed birth dose vaccination among infants, one study assessed vaccination in elementary school children and 17 studies assessed vaccination in adults. Among studies assessing adult vaccination, a pooled estimate of 38% (95%CI: 21-56%) of people initiated vaccination, with high heterogeneity across studies (range: 0.5-93%; I square: 99.9%). A stratified analysis by HBV vaccination strategy demonstrated that in the studies providing on-site vaccination, the uptake was 78% (95%CI: 62-94%), significantly higher compared to 27% (95%CI: 13-42%) in studies referring participants to an external site for vaccination. Conclusion This systematic review identified a wide variety of interventions, mostly multi-component interventions, to enhance HBV screening, linkage to HBV clinical care, and HBV vaccination coverage. High heterogeneity was observed in effectiveness of interventions in all three domains of screening, linkage to care, and vaccination. Strategies identified to boost the effectiveness of interventions included providing on-site HBV testing and vaccination (versus referral for testing and vaccination) and including community education focussed on HBV or liver cancer in an HBV screening program. Further studies are needed to evaluate the effectiveness of more novel interventions (e.g., point of care testing) and interventions specifically including Indigenous populations, people who inject drugs, men who have sex with men, and people incarcerated.
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