Rozprawy doktorskie na temat „Hormones”
Utwórz poprawne odniesienie w stylach APA, MLA, Chicago, Harvard i wielu innych
Sprawdź 50 najlepszych rozpraw doktorskich naukowych na temat „Hormones”.
Przycisk „Dodaj do bibliografii” jest dostępny obok każdej pracy w bibliografii. Użyj go – a my automatycznie utworzymy odniesienie bibliograficzne do wybranej pracy w stylu cytowania, którego potrzebujesz: APA, MLA, Harvard, Chicago, Vancouver itp.
Możesz również pobrać pełny tekst publikacji naukowej w formacie „.pdf” i przeczytać adnotację do pracy online, jeśli odpowiednie parametry są dostępne w metadanych.
Przeglądaj rozprawy doktorskie z różnych dziedzin i twórz odpowiednie bibliografie.
Pajor, Ana Marie. "Transport of amino acids and glucose in brush border membrane vesicles from the gills of the marine mussel, Mytilus edulis". Diss., The University of Arizona, 1988. http://hdl.handle.net/10150/184462.
Pełny tekst źródłaBetley, Stephen. "Regulation of hepatocyte function by insulin, growth hormone and thyroid hormones". Thesis, University of Newcastle Upon Tyne, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287415.
Pełny tekst źródłaScarano, Wellerson Rodrigo. "Repercussões histopatologicas na prostata ventral do gerbilo da Mongolia (Merinones unguiculatus) apos suplementação por hormonios esteroides". [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317918.
Pełny tekst źródłaTese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia
Made available in DSpace on 2018-08-07T17:58:14Z (GMT). No. of bitstreams: 1 Scarano_WellersonRodrigo_D.pdf: 4897591 bytes, checksum: ce5fe2f21b6836d646532424d518315c (MD5) Previous issue date: 2006
Resumo: O tecido prostático é susceptível aos desníveis hormonais provocados, principalmente pelo processo de envelhecimento. A hiperplasia benigna prostática e o câncer de próstata são doenças que acometem uma grande parcela da população masculina, e parecem estar envolvidas com alterações hormonais. Por isso, o esclarecimento dos processos celulares e teciduais envolvendo os hormônios sexuais: testosterona e estradiol são, sem dúvida, importantes para o entendimento da etiologia desses processos patológicos. O gerbilo (Meriones unguiculatus) foi utilizado como modelo experimental pois, segundo a literatura, é susceptível ao aparecimento de lesões autóctones e responde bem à carcinogênese experimental, mostrando-se um bom modelo experimental. Numa primeira etapa, foram utilizados animais de três idades diferentes: púbere, adulta e senil. Esses animais foram submetidos à suplementação androgênica e as próstatas ventrais foram destinadas a análises histopatológicas, quantitativas, imunocitoquímicas e ultraestruturais. Foi observado aumento no peso da glândula e também na altura das células epiteliais em todas as idades. Tal aumento reflete o aumento da capacidade sintética observada pela dilatação das organelas de síntese, às vezes de aspecto vesiculoso, ocupando toda a região supranuclear. Nos animais adultos e velhos foram notadas regiões hiperplásicas e displásicas freqüentemente associadas a Neoplasias Intraepiteliais de diferentes graus e a adenocarcinomas. Houve aumento na espessura da camada de células musculares lisas (CML) ao redor dos ácinos nos animais púberes e adultos, enquanto nos animais velhos houve diminuição dessa camada. Além disso, as CML se mostraram aparentemente hipertróficas e com maior atividade sintética nos animais púberes e adultos. Foi notado aparente aumento da vascularização periacinar, onde se observou a presença de freqüentes vasos sanguíneos em todas as idades após o tratamento. Ademais, em todas as idades foi observado aumento da densidade de marcação de receptores androgênicos após o tratamento, evidenciando a possível relação desses receptores com os efeitos observados. Em uma segunda etapa experimental, avaliou-se o efeito do estradiol sobre o tecido prostático intacto e hipoandrogênico em animais adultos, tentando com isso simular situações de descompensação hormonal, típicas da senilidade. As alterações epiteliais foram freqüentes nos animais tratados com estradiol onde se observou aumento na altura das células epiteliais, aparecimento de regiões de intensa displasia e hiperplasia, e a formação de PINs. Outro aspecto que independe da presença da testosterona é o arranjo dos elementos fibrilares e não fibrilares da matriz extracelular entre as CML, apontando para um possível papel dessas células no rearranjo e na síntese desses componentes após os tratamentos estrogênicos. Nos animais castrados observou-se acúmulo de elementos da matriz extracelular sob o epitélio e em animais intactos presença desses elementos dispersos e escassos. Em ambos os grupos: intactos e castrados, notou-se que as CML e os fibroblastos apresentam fenótipo secretor acentuado após o tratamento com estradiol. Houve aumento na densidade de marcação ERa e AR positivos em regiões de hiperplasia apontando para um possível papel desses receptores na formação de lesões pré-malígnas e malignas. Portando, conclui-se que o gerbilo é susceptível a ação da testosterona e do estradiol, os quais provocam desarranjos estruturais e ultraestruturais de cunho patológico e funcional, mostrando-se um ótimo modelo para o estudo das doenças prostáticas de etiologia hormonal
Abstract: Not informed.
Doutorado
Biologia Celular
Doutor em Biologia Celular e Estrutural
Uchuya, Castillo Luis Joël. "Étude du signal véhiculé par les hormones thyroïdiennes dans la physiopathologie intestinale". Thesis, Lyon, 2017. http://www.theses.fr/2017LYSE1221/document.
Pełny tekst źródłaThe intestinal epithelium is characterized by constant renewal and differentiation due to the presence of stem cells located at the bottom of the crypts. This permanent renewal depends on the crosstalk between several signaling pathways whose alteration can lead to tumor initiation and progression. Our team demonstrated the implication of the thyroid hormones and their nuclear receptor TRa1 in the control of the intestinal epithelium homeostasis through the regulation of the Wnt pathway. Moreover, the overexpression of TRa1 in the intestinal epithelium of mice is sufficient to promote tumor initiation, and in an APC loss of function context, it accelerates tumor progression highlighting its oncogenic potential. Through gene expression profiling, we highlighted an activation of the Wnt pathway activity by TRa1 during tumor progression. We next confirm these results in human patient samples by demonstrating that high TRa1 expression in tumors invariably is associated with an increased Wnt pathway activity. In addition, in CRC cell lines, TRa1-associated WNT pathway activation enhances their aggressiveness. Altogether these results showed the implication of TRa1 in intestinal carcinogenesis and open avenues for new therapeutic treatment against TRa1 targeting TRa1
McGinley, Susan. "Insect Hormones and Anti-Hormones: Protecting Plants and Public Health". College of Agriculture and Life Sciences, University of Arizona (Tucson, AZ), 1995. http://hdl.handle.net/10150/622378.
Pełny tekst źródłaHussein, Mohamed Osman. "Hormonal modulation of Leydig cell membrane luteinizing hormone receptors /". The Ohio State University, 1986. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487267024995937.
Pełny tekst źródłaStevens, Jeffrey David. "LHRH fusion protein vaccines in beef heifers and bovine ectopic ovarian xenografting". Online access for everyone, 2004. http://www.dissertations.wsu.edu/Dissertations/Fall2004/J%5FStevens%5F092204.pdf.
Pełny tekst źródłaEdholm, Therese. "The role of incretin peptides and ghrelin in upper gut motility and metabolic control /". Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-937-8/.
Pełny tekst źródłaKallmeier, Robert Charles. "Molecular studies of luteinizing hormone-releasing hormones in the brain of domestic fowl". Thesis, University of Reading, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306719.
Pełny tekst źródłaThompson, Jennifer Jo, Cheryl Ritenbaugh i Mark Nichter. "Why women choose compounded bioidentical hormone therapy: lessons from a qualitative study of menopausal decision-making". BIOMED CENTRAL LTD, 2017. http://hdl.handle.net/10150/626039.
Pełny tekst źródłaHassan, A. Quamrul. "Molecular complementation of mutant thyroid hormone receptors that disrupt transactivation mechanism". Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file 9.11 Mb., 175 p, 2006. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3205433.
Pełny tekst źródłaDavies, Mina C. G. "Factors affecting embryo mortality in ewe lambs". Thesis, Aberystwyth University, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.340852.
Pełny tekst źródłaVillar, David. "Hormonal regulation of the fibre growth and moult cycle in cashmere goats". Thesis, University of Aberdeen, 1998. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU106170.
Pełny tekst źródłaZheng, Jianfei. "Development of thyroid hormone receptor-targeting conjugates". Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 130 p, 2009. http://proquest.umi.com/pqdweb?did=1833641661&sid=5&Fmt=2&clientId=8331&RQT=309&VName=PQD.
Pełny tekst źródłaKask, Kristiina. "Hormones, Mood and Cognition". Doctoral thesis, Uppsala universitet, Institutionen för kvinnors och barns hälsa, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9365.
Pełny tekst źródłaLe, Roux Carel Wynand. "Gut hormones and appetite". Thesis, Imperial College London, 2005. http://hdl.handle.net/10044/1/7840.
Pełny tekst źródłaARNIAUD, DENIS. "Rhumatismes inflammatoires et hormones". Aix-Marseille 2, 1994. http://www.theses.fr/1994AIX20867.
Pełny tekst źródłaBaynham, Mark Kevin. "Gibberellin plant growth hormones". Thesis, University of Sussex, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328329.
Pełny tekst źródłaDonald, Angela Sheila. "Sex hormones in dermatophytes". Thesis, University of Aberdeen, 1990. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU078356.
Pełny tekst źródłaRodway, Marie R. "Effector mechanisms in the endocrine control of steroidogenesis". Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/31411.
Pełny tekst źródłaMedicine, Faculty of
Obstetrics and Gynaecology, Department of
Graduate
Levin, Tracy M. "Evidence for the existence of juvenile hormone in the horseshoe crab". Link to electronic thesis, 2003. http://www.wpi.edu/Pubs/ETD/Available/etd-0528103-140647.
Pełny tekst źródłaGross, Bernadette. "Structure du gène humain du récepteur de la TSH : polarisation des récepteurs de la LH dans les cellules MDCK". Paris 11, 1993. http://www.theses.fr/1993PA11T016.
Pełny tekst źródłaBrischoux, Frédéric. "Etude ontogénétique du système à hormone de mélano-concentration (MCH) chez le rat et régionalisation de l'hypothalamus". Besançon, 2002. http://www.theses.fr/2002BESA0006.
Pełny tekst źródłaMarion, Sébastien. "Influence de la dynamique intracellulaire des kinases spécifiques des récepteurs couplés aux protéines G (GRKs) et des β-arrestines sur l'état d'activation du récepteur de l'hormone folliculo-stimulante (RFSH)". Tours, 2002. http://www.theses.fr/2002TOUR4001.
Pełny tekst źródłaBillon, Cyrielle. "Hormones thyroïdiennes et désordres métaboliques". Thesis, Lyon, École normale supérieure, 2012. http://www.theses.fr/2012ENSL0720.
Pełny tekst źródłaThyroid hormones (TH) play a role in many processes such as development, growth and metabolic control. HT bind to their nuclear receptors, the TR (TRalpha and beta). TRs belong to the superfamily of nuclear hormone receptors. These TRs are transcription factors whose activity is controlled by the binding of their ligand. During my PhD thesis I focused on the roles of TR in two contexts. Initially, I highlighted the role of TRbeta in the regulation of the hepatic metabolism via the activation of the key gene ChREBP, a glucose-responsive transcription factor. Using transgenic animal models and in vitro systems, I showed that TRbeta up regulates the expression of ChREBP via binding to its response element present in the promoter. I have shown that this activation is isoform specific and independent of another nuclear receptor LXR. In a second part, I demonstrated that the TRalpha isoform is involved in the development of atherosclerosis, a cardiovascular disease. Using a transgenic mice model, I observed that TRalpha has an anti-inflammatory effect and it is also able to stimulate the reverse cholesterol transport by macrophages. The absence of this receptor induces an increase in the development of the disease as well as in the level of circulating cytokines in mice. The deletion of TRalpha decreases the cholesterol efflux in bone marrow derived macrophages in vitro and it is correlated with a decrease of ABCA1 expression. All these data suggest a novel role of HT / TR in the development of human pathologies, including an anti-inflammatory role assumed, but recently demonstrated
Diekman, Mattheus Jozef Maria. "Thyroid hormones, lipids and endothelium". [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2000. http://dare.uva.nl/document/84351.
Pełny tekst źródłaSmith, Kirsty Louise. "Metabolic hormones and energy homeostasis". Thesis, Imperial College London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.411789.
Pełny tekst źródłaWatts, Julian Daniel. "Thymic hormones : structure and function". Thesis, University of Portsmouth, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328160.
Pełny tekst źródłaCleator, M. "Developmental hormones in parasitic nematodes". Thesis, University of Liverpool, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356250.
Pełny tekst źródłaO'Hanlon, Graham Michael. "Developmental hormones in ascarid nematodes". Thesis, University of Liverpool, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.293137.
Pełny tekst źródłaFoster, Jeremy Michael. "Hormones and isoprenoids in trematodes". Thesis, University of Liverpool, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303679.
Pełny tekst źródłaGooding, Kim Mary. "Sex hormones and the microcirculation". Thesis, University of Exeter, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248164.
Pełny tekst źródłaOh, Hannah. "Lifestyle, Hormones, and Breast Cancer". Thesis, Harvard University, 2014. http://nrs.harvard.edu/urn-3:HUL.InstRepos:14117761.
Pełny tekst źródłaNeary, Nicola Marguerite. "Gut hormones and energy homeostasis". Thesis, Imperial College London, 2007. http://hdl.handle.net/10044/1/7152.
Pełny tekst źródłaVon, Boetticher S. "Investigating the mechanism of transcriptional regulation of the gonadotropin-releasing hormone receptor (GnRHR) gene by dexamethasone". Thesis, Link to the online version, 2008. http://hdl.handle.net/10019/1796.
Pełny tekst źródłaBarsnick, Rosa. "Hormones of Energy Metabolism in Critically Ill Foals: Insulin, Glucagon, Leptin, Adiponectin, Ghrelin and Growth Hormone". The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1275523617.
Pełny tekst źródłaWormald, Patricia J. "GnRH and neuropeptide regulation of gonadotropin secretion from cultured human pituitary cells". Doctoral thesis, University of Cape Town, 1988. http://hdl.handle.net/11427/27168.
Pełny tekst źródłaDamasceno, Danielle Zanerato. "Indução a espermiação do mandi-pintado, Pimelodus britskii no período reprodutivo (Teleostei: Pimelodidae) /". Jaboticabal, 2014. http://hdl.handle.net/11449/108928.
Pełny tekst źródłaBanca: Sérgio Ricardo Batlouni
Banca: Alexandre Ninhaus Silveira
Resumo: O objetivo deste trabalho foi caracterizar o sêmen de Pimelodus britskii através de diferentes métodos de coleta e doses hormonais. O experimento foi executado em dois períodos reprodutivos, novembro/2011 a março/2012 e outubro/2012 a março/2013. No primeiro período reprodutivo (Experimento 1) em todos os meses 12 peixes foram divididos em dois grupos, um grupo induzido com Extrato Hipofisádo de Carpa-EHC (3,0 mg.kg-1) e um grupo sem indução hormonal, após 240 unidades térmicas acumuladas-UTAs os peixes dos dois grupos foram eutanasiados e tiveram seus testículos macerados. No segundo período reprodutivo (Experimento 2) 30 peixes foram divididos em cinco grupos para comparação de diferentes doses de EHC e Gonadotrofina Coriônica humana-hCG na espermiação (T1: controle; T2: 3,0 mg.kg-1EHC; T3: 0,5 mg.kg-1+3,0 mg.kg-1EHC; T4: 0,5mg.kg-1+7,0 mg.kg-1EHC; T5: 200UI.kg-1hCG), sendo que neste período os mesmos peixes foram utilizados todos os meses, e após 240 UTAs o sêmen foi coletado através de massagem abdominal. Foram avaliadas a motilidade e velocidade espermática por meio do software CASA (Computer Assisted Sperm Analysis). As variáveis seminais por meio do Statistica 7.0. Por meio da maceração, verificou-se alterações na cor (branco a amarelado), pH (6 a 7) e concentração espermática (11,9x109±4,16x109 a 9,15x109±3,55x109 espermatozoides/mL-1). O volume mostrou relação entre meses e tratamentos (p<0,05). Para todos os exemplares a motilidade foi superior em nov/2011, diminuindo gradativamente até fev/2012. O mesmo ocorreu em relação aos valores dos IGS (p<0,05), mostrando a ação da indução hormonal no volume seminal. Os peixes do Experimento1 liberaram volume reduzido de sêmen ...
Abstract: The aim of this study was to characterize the semen Pimelodus britskii through different collection methods and hormonal doses. The experiment was run in two reproductive periods, November/2011 to March/2012 and October/2012 to March/2013. In the first breeding season (Experiment 1 ) in all months 12 fish were divided into two groups, one experimental group with Carp Pituitary Extract - EHC (3.0 mg.kg- 1) and a group without hormonal induction, after 240 units accumulated thermal-UTA fish from both groups were euthanized and had their macerated testes. In the second reproductive period (Experiment 2 ) 30 fish were divided into five groups for comparison of different doses of human Chorionic Gonadotropin-hCG and EHC in spermiation (T1: Control, T2: 3,0mg.kg-1 EHC, T3: 0,5 mg.kg-1 +3,0 mg.kg-1 EHC , T4: 0,5 mg.kg-1 +7,0 mg.kg-1 EHC , T5: 200UI.kg-1 hCG ) , and in this period the same fish were used every month, and after 240 UTA semen was collected by abdominal massage. Motility and sperm velocity were evaluated through the CASA software (Computer Assisted Sperm Analysis). The seminal variables using Statistica 7.0. Through the soaking, there was color change (white to yellow), pH (6 to 7) and sperm concentration (11,9x109±4,16x109 to 9,15x109±3,55x109 spermatozoa/mL-1). The volum months showed relationship between treatments (p<0,05). For all copies motility was higher in November/2011, decreasing gradually until February/2012. The same occurred with the values of the IGS (p<0,05), showing the action of hormonal induction in seminal volume ...
Mestre
Baillot, Aurélie. "Réentraînement à l'effort chez des sujets atteints du syndrome métabolique : impact sur les réponses hormonales et la qualité de vie". Thesis, Orléans, 2010. http://www.theses.fr/2010ORLE2038/document.
Pełny tekst źródłaThe metabolic syndrome (Mets) is a cluster of metabolically related abnormalities (abdominal obesity insulin resistance, dyslipidemia and hypertension), with no obvious defined cause. In the literature, individuals with Mets seem to have hormonal and quality of life alterations, but this concept is relatively recent and few studies have investigated the effects of regular physical activity on these parameters. Our work divides into two parts. First, we studied the correlation between plasmatic and saliva adrenocortical hormonal at rest and during exercise in men with Mets. It appears that the correlation obtained at rest is maintained during exercise. Secondly, we studied the effects of 8 weeks of controlled regular physical activity on the pituitary, adrenocortical and androgenic hormones, physical capacity and quality of life in men with Mets. Our results show that aerobic exercise training does not induce anthropometric modifications but decreases significantly basal saliva cortisol without any other hormonal change. In parallel, physical capacity and psychosocial impact dimension of quality of life are significantly improved. These data confirm the beneficial effect of regular physical activity on physical capacity and quality of life. It is tempting to suggest that saliva cortisol could be an early marker reflecting improvement of physical capacities in individuals with Mets. Further works with larger cohort and longer training programs are required to complete this work
Wihlbäck, Anna-Carin. "Ovarian hormones and effects in the brain : studies of neurosteroid sensitivity, serotonin transporter and serotonin2A receptor binding in reproductive and postmenopausal women". Umeå : Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-365.
Pełny tekst źródłaWang, Ying. "Molecular and functional characterization of the prolactin receptor, prolactin-releasing peptide receptor, and growth hormone-releasing hormone receptor genes in chicken". Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/HKUTO/record/B39556864.
Pełny tekst źródłaRoberts, April M. "Steroid hormone treatments alter growth characteristics in transformed human ovarian cell lines". Virtual Press, 2003. http://liblink.bsu.edu/uhtbin/catkey/1265095.
Pełny tekst źródłaPowell, R. C. "Evolution of the structure and function of vertebrate brain gonadotropin-releasing hormone". Master's thesis, University of Cape Town, 1986. http://hdl.handle.net/11427/27201.
Pełny tekst źródłaVan, Koesveld Marika J. "Potential applications of growth hormone-releasing peptide-6 as a growth promotant". Thesis, The University of Sydney, 2003. https://hdl.handle.net/2123/28158.
Pełny tekst źródłaFradinger, Erica Aileen. "Isolation and developmental expression of growth hormone-releasing hormone (GRF), pituitary adenylate cyclase-activating polypeptide (PACAP) and their receptors in the zebrafish, Danio rerio". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/NQ62513.pdf.
Pełny tekst źródłaEriksson, Maria. "Adipocyte-derived hormones and cardiovascular disease". Doctoral thesis, Umeå universitet, Institutionen för folkhälsa och klinisk medicin, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-36679.
Pełny tekst źródłaDaja, Mirella Maria. "Enzyme activities associated with gonadotropic hormones". Thesis, University of Auckland, 1993. http://hdl.handle.net/2292/2311.
Pełny tekst źródłaAlehagen, Siw. "Fear pain stress hormones during labor /". Linköping : Univ, 2002. http://www.bibl.liu.se/liupubl/disp/disp2002/med730s.pdf.
Pełny tekst źródłaAl-Mana, D. "Ovarian steroid hormones and auditory function". Thesis, University College London (University of London), 2013. http://discovery.ucl.ac.uk/1386639/.
Pełny tekst źródłaFarquharson, Roy G. "Fetal abstraction of placental steroid hormones". Thesis, University of Aberdeen, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328653.
Pełny tekst źródła