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Чемич, Оксана Миколаївна, Оксана Николаевна Чемич, Oksana Mykolaivna Chemych, Я. Л. Кравцова i А. А. Олефір. "Structure of opportunistic infections in patients with HIV- infection". Thesis, Sumy State University, 2018. http://essuir.sumdu.edu.ua/handle/123456789/74893.
Pełny tekst źródłaДиагностика первой и второй стадии ВИЧ-инфекции невысока. Оппортунистические инфекции и сопутствующие заболевания обостряют течение ВИЧ-инфекции. Наиболее распространенной оппортунистической инфекцией является кандидоз ротоглотки. Хронический вирусный гепатит С и метаболическая кардиомиопатия преобладают в структуре сопутствующей патологии.
Diagnosis of the first and second stages of HIV-infection is low. Opportunistic infections and concomitant illnesses aggravate the course of HIV-infection. The most common opportunistic infection is oropharyngeal candidiasis. Chronic viral hepatitis C and metabolic cardiomyopathy are predominate in the structure of concomitant pathology.
Uccellini, L. "HOST GENETIC INFLUENCE ON HIV AND HCV INFECTIONS". Doctoral thesis, Università degli Studi di Milano, 2013. http://hdl.handle.net/2434/215587.
Pełny tekst źródłaNelson, Patrick William. "Mathematical models of HIV pathogenesis and immunology /". Thesis, Connect to this title online; UW restricted, 1998. http://hdl.handle.net/1773/6783.
Pełny tekst źródłaTakehisa, Jun. "HIV Mixed Infections and Recombination". Kyoto University, 1999. http://hdl.handle.net/2433/181727.
Pełny tekst źródłaLau, Katherine Aik Hee. "Biology and molecular biology of new HIV-1 recombinant forms from Malaysia". Connect to full text, 2008. http://hdl.handle.net/2123/4129.
Pełny tekst źródłaTitle from title screen (viewed 31 March 2009). Submitted in fulfilment of the of the requirements for the degree of Doctor of Philosophy to the Discipline of Medicine, Faculty of Medicine. Degree awarded 2009; thesis submitted 2008. Includes bibliographical references. Also available in print form.
Falconer, Karolin. "HIV-1/HCV co-infection immunity and viral dynamics /". Stockholm, 2010. http://diss.kib.ki.se/2010/978-91-7409-762-7/.
Pełny tekst źródłaCherner, Mariana. "Ethnicity and the experience of stress, coping, social support, and depressive symptoms in persons infected with HIV /". Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 1997. http://wwwlib.umi.com/cr/ucsd/fullcit?p9804025.
Pełny tekst źródłaVödrös, Dalma. "Receptor use of primate lentiviruses /". Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-497-6/.
Pełny tekst źródłaSchmidt, Fabian. "On the evolution of HIV-1 virulence". Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708265.
Pełny tekst źródłaLong, Elizabeth Michelle. "Genetic and co-receptor characterization of viral diversity early in human immunodeficiency virus type 1 infection /". Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/4997.
Pełny tekst źródłaDasgupta, Abhijit. "Parametric identifiability and related problems /". Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/9602.
Pełny tekst źródłaWeinberger, Beverley Slome Kloss Jacqueline D. "Posttraumatic stress in adolescents with HIV and its relationship with treatment adherence : the role of health beliefs /". Philadelphia, Pa. : Drexel University, 2010. http://hdl.handle.net/1860/3221.
Pełny tekst źródłaJohn, Grace Chiramukuthu. "Genital shedding and intrapartum transmission of HIV-1 /". Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/10956.
Pełny tekst źródłaBakari, Muhammad. "The natural history of HIV-1 infection and preparations for HIV vaccine trials in Tanzania /". Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-908-4/.
Pełny tekst źródłaKolotylo, T. R. "Peculiarities of HIV infection with active tuberculosis in association with other opportunistic infections". Thesis, БДМУ, 2020. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18222.
Pełny tekst źródłaKalonji, Kabasele Muboyayi Hubert. "Demographic profile of pregnant HIV-positive women in Postmasburg, South Africa". Thesis, University of Limpopo (Medunsa Campus), 2011. http://hdl.handle.net/10386/449.
Pełny tekst źródłaBackground: South Africa hosts the largest number of pregnant HIV-positive women, accounting for almost 15% of the global total. Many amongst these HIV-positive pregnancies are unplanned and may be related to reproductive unmet needs, sexual risky behaviours, and/or community, contextual and individual factors that may determine and/or make these HIV-infected women to fall pregnant. The occurrence of an HIV-positive pregnancy in our region implies however the practice of unprotected sex, and is associated with the risk of reinfection with a different strain of HIV as well as with the risk of HIV transmission to an uninfected male partner and to the offspring. Knowing the demographic profile of HIV-infected women who become pregnant and experience parenthood as well as the circumstances of occurrence of their pregnancies is necessary for developing policies and interventions aimed at addressing the reproductive needs of this subpopulation, thus preventing HIV-positive unintended pregnancies as well as the horizontal and vertical transmission of HIV. Objectives: This study had three objectives. The first objective was to describe the demographic profile of pregnant HIV-positive women attending antenatal care (ANC) in public sector clinics in Postmasburg, South Africa. The second study objective was to determine the proportion of these pregnant HIV-infected women who were aware of their HIV-positive status prior to the occurrence of their current pregnancy. Lastly, the third objective sought to describe the circumstances of occurrence of their current pregnancy. Methodology: We used a quantitative descriptive design to collect data on 41 consecutive pregnant HIV-positive women who attended ANC at three public sector clinics in Postmasburg, from September to December 2010. Participants were administered a structured pre-tested questionnaire in their home language by trained interviewers. The study instrument was designed to collect data related to participants‘ socio-demographic characteristics, the time-period of HIV- v positive diagnosis relative to their current pregnancy, and the circumstances of occurrence of their current pregnancy. Results: The analyses of the study results showed that pregnant HIV-positive women attending ANC in Postmasburg were likely to be young (mean age, 27.71 ± 5.72 years), never married (56.10%), Afrikans (65.9%) and Setswana speakers (58.52%) of low socioeconomic status, with no or one child (65.85%). The majority of participants (63.4%) were from a predominantly informal settlement; 78% were unemployed while 61% were either devoid of any income or were living with Rands 500 or less. Sex mixing was common in the 15-19 years-old, involving 80% of respondents of this age category. Most of respondents (78.05%) became aware of their HIV-positive diagnosis during their current pregnancy that was unplanned in 73.17%. The study findings also revealed low levels of pregnancy intendedness (31.71%), hormonal contraceptives use (24.9%) and condoms uptake (34.15%), with high rates of condoms failure among users (87.12%). Respondents also reported other circumstances of occurrence of their current pregnancy, including, irregular condoms use (14.29% of condom users), partner refusal to use condom (10%), stopping contraceptives use because of side effects (50% of users), partner‘s pressure (12% of participants), coerced sex (2.4%) and having had sex under the influence of alcohol (2.4%). Conclusion: These results highlight the need for improving the reproductive health services that are offered to HIV-positive individuals. Integrating PMTCT and Family planning services, training health workers in issues related to the reproductive rights and reproductive health of HIV-infected individuals, systematically offering HIV counseling and testing to women of childbearing age who come into contact with health facilities for any reason and adequately informing HIV-positive women of childbearing age about available reproductive options, planned conception and safer motherhood, are necessary for preventing unintended HIV-positive pregnancies as well as the horizontal and vertical transmission of HIV.
Nkambule, Jeaniffer Dekeledi. "The Emotional experiences of HIV-positive married women wanting to bear children: An exploratory study". Thesis, University of Limpopo (Medunsa Campus), 2012. http://hdl.handle.net/10386/1083.
Pełny tekst źródłaRecent literature on childbearing and HIV has indicated a plethora of evidence suggesting that many women living with HIV continue to desire children, become pregnant and give birth after knowing their HIV status. This desire to have children has been associated with the availability of HAART and PMTC interventions and its improvement in the quality of life for HIV-positive women. This study aimed at exploring the emotional experiences of HIV-positive married women wanting to bear children. A qualitative research design was used to explore the above mentioned aim. Through the use of semi-structured interviews a sample of 12 HIV-positive married women were purposefully selected. The participants were chosen from Tshepang clinic at Dr. George Mukhari Hospital situated in the township of Ga-Rankuwa using a purposive sampling design. Semi-structured interviews using interview guide were conducted to explore their unique and subjective emotional experiences of being HIV, married and in need of a child. The process of data analysis in the current study was guided by phenomenological approach in order to allow the inherent meaning of the data to emerge without being distorted. The findings of these study revealed that the experiences surrounding HIV positive diagnosis, marriage and childbearing proves to be associated with overwhelming emotional experiences for women in the current study. Most of the participants in this study viewed motherhood as a unique, subjective and a personal fulfilment for all women irrespective of their HIV status. Participants felt that children stabilise a marriage by giving it meaning. A decision to conceive for some participants is influenced by pressure as a result of their marital, social and situational context
Lizeng, Qin. "Dynamics of the HIV-2-specific immunoglobulin A(IgA) response /". Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-259-4/.
Pełny tekst źródłaHawes, Stephen Edward. "HIV-1, HIV-2, and dual infection with HIV-1 and HIV-2 are associated with increased risk for human papillomavirus (HPV) and high grade squamous intraepithelial lesions (HSIL) in Senegal, West Africa /". Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/10881.
Pełny tekst źródłaNolte, Jeanine Lucasta. "The formulation and refinement of a polymerase chain reaction (PCR) assay for early diagnosis of paediatric HIV infection and genetic analysis of variants involved in vertical transmission of HIV-1". Master's thesis, University of Cape Town, 1996. http://hdl.handle.net/11427/26361.
Pełny tekst źródłaUrassa, Willy Shileanga Kikoka. "HIV-1 infection in Tanzania : HIV antibody testing strategies and lymphocyte subset determinations /". Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-530-1.
Pełny tekst źródłaHutchinson, Angela Blair. "A health technology assessment of HIV counseling and testing technologies evidence of effectiveness, cost-effectiveness and the consumer perspective /". Available online, Georgia Institute of Technology, 2004:, 2003. http://etd.gatech.edu/theses/available/etd-06072004-131203/unrestricted/hutchinson%5Fangela%5Fb%5F200405%5Fphd.pdf.
Pełny tekst źródłaBarnes, Nielan. "Transnational networks and community-based organizations: the dynamics of AIDS activism in Tijuana and Mexico City /". Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC IP addresses, 2005. http://wwwlib.umi.com/cr/ucsd/fullcit?p3167838.
Pełny tekst źródłaÅsander, Ann-Sofie. "HIV-infected African parents living in Stockholm social networks, disclosure, parenthood, and knowledge about HIV-transmission /". Stockholm : Infectious diseases unit, Karolinska Institutet, 2010. http://diss.kib.ki.se/2010/978-91-7409-774-0/.
Pełny tekst źródłaDe, la Harpe Alana. "A comparative analysis of mathematical models for HIV epidemiology". Thesis, Stellenbosch : Stellenbosch University, 2015. http://hdl.handle.net/10019.1/96983.
Pełny tekst źródłaENGLISH ABSTRACT: HIV infection is one of the world’s biggest health problems, with millions of people infected worldwide. HIV infects cells in the immune system, where it primarily targets CD4+ T helper cells and without treatment, the disease leads to the collapse of the host immune system and ultimately death. Mathematical models have been used extensively to study the epidemiology of HIV/AIDS. They have proven to be effective tools in studying the transmission dynamics of HIV. These models provide predictions that can help better our understanding of the epidemiological patterns of HIV, especially the mechanism associated with the spread of the disease. In this thesis we made a functional comparison between existing epidemiological models for HIV, with the focus of the comparison on the force of infection (FOI). The spread of infection is a crucial part of any infectious disease, as the dynamics of the disease depends greatly on the rate of transmission from an infectious individual to a susceptible individual. First, a review was done to see what deterministic epidemiological models exist. We found that many manuscripts do not provide the necessary information to recreate the authors’ results and only a small amount of the models could be simulated. The reason for this is mainly due to a lack of information or due to mistakes in the article. The models were divided into four categories for the analysis. On the basis of the FOI, we distinguished between frequency- or density-dependent transmission, and as a second criterion we distinguished models on the sexual activity of the AIDS group. Subsequently, the models were compared in terms of their FOI, within and between these classes. We showed that for larger populations, frequency-dependent transmission should be used. This is the case for HIV, where the disease is mainly spread through sexual contact. Inclusion of AIDS patients in the group of infectious individuals is important for the accuracy of transmission dynamics. More than half of the studies that were selected in the review assumed that AIDS patients are too sick to engage in risky sexual behaviour. We see that including AIDS patients in the infectious individuals class has a significant effect on the FOI when the value for the probability of transmission for an individual with AIDS is bigger than that of the other classes. The analysis shows that the FOI can vary depending on the parameter values and the assumptions made. Many models compress various parameter values into one, most often the transmission probability. Not showing the parameter values separately makes it difficult to understand how the FOI works, since there are unknown factors that have an influence. Improving the accuracy of the FOI can help us to better understand what factors influence it, and also produce more realistic results. Writing the probability of transmission as a function of the viral load can help to make the FOI more accurate and also help in the understanding of the effects that viral dynamics have on the population transmission dynamics.
AFRIKAANSE OPSOMMING: MIV-infeksie is een van die wêreld se grootste gesondheidsprobleme, met miljoene mense wat wêreldwyd geïnfekteer is. MIV infekteer selle in die immuunstelsel, waar dit hoofsaaklik CD4+ T-helperselle teiken. Sonder behandeling lei die siekte tot die ineenstorting van die gasheer se immuunstelsel en uiteindelik sy dood. Wiskundige modelle word breedvoerig gebruik om die epidemiologie van MIV/vigs te bestudeer. Die modelle is doeltreffende instrumente in die studie van die oordrag-dinamika van MIV. Hulle lewer voorspellings wat kan help om ons begrip van epidemiologiese patrone van MIV, veral die meganisme wat verband hou met die verspreiding van die siekte, te verbeter. In hierdie tesis het ons ‘n funksionele vergelyking tussen bestaande epidemiologiese modelle vir MIV gedoen, met die fokus van die vergelyking op die tempo van infeksie (TVI). Die verspreiding van infeksie is ‘n belangrike deel van enige aansteeklike siekte, aangesien die dinamika van die siekte grootliks afhang van die tempo van oordrag van ‘n aansteeklike persoon na ‘n vatbare persoon. ‘n Oorsig is gedoen om te sien watter kompartementele epidemiologiese modelle alreeds bestaan. Ons het gevind dat baie van die manuskripte nie die nodige inligting voorsien wat nodig is om die resultate van die skrywers te repliseer nie, en slegs ‘n klein hoeveelheid van die modelle kon gesimuleer word. Die rede hiervoor is hoofsaaklik as gevolg van ‘n gebrek aan inligting of van foute in die artikel. Die modelle is in vier kategorieë vir die analise verdeel. Op grond van die TVI het ons tussen frekwensie- of digtheidsafhanklike oordrag onderskei, en as ‘n tweede kriterium het ons die modelle op die seksuele aktiwiteit van die vigs-groep onderskei. Daarna is die modelle binne en tussen die klasse vergelyk in terme van hul TVIs. Daar is gewys dat frekwensie-afhanklike oordrag gebruik moet word vir groter bevolkings. Dit is die geval van MIV, waar die siekte hoofsaaklik versprei word deur seksuele kontak. Die insluiting van die vigs-pasiënte in die groep van aansteeklike individue is belangrik vir die akkuraatheid van die oordrag-dinamika van MIV. Meer as helfte van die uitgesoekte studies aanvaar dat vigs-pasiënte te siek is om betrokke te raak by riskante seksuele gedrag. Ons sien dat die insluiting van vigs-pasiënte in die groep van aansteeklike individue ‘n beduidende uitwerking op die TVI het wanneer die waarde van die waarskynlikheid van oordrag van ‘n individu met vigs groter is as dié van die ander klasse. Die analise toon dat die TVI kan wissel afhangende van die parameter waardes en die aannames wat gemaak is. Baie modelle voeg verskeie parameter waardes bymekaar vir die waarskynlikheid van oordrag. Wanneer die parameter waardes nie apart gewys word nie, is dit moeilik om die werking van die TVI te verstaan, want daar is onbekende faktore wat ‘n invloed op die TVI het. Die verbetering van die akkuraatheid van die TVI kan ons help om die faktore wat dit beïnvloed beter te verstaan, en dit kan ook help om meer realistiese resultate te produseer. Om die waarskynlikheid van oordrag as ‘n funksie van die viruslading te skryf kan help om die TVI meer akkuraat te maak en dit kan ook help om die effek wat virale dinamika op die bevolkingsoordrag-dinamika het, beter te verstaan.
Harry, Karuna. "The changing knowledge and expectations of public health nurses in a HIV/AIDS training programme for managers". Thesis, Rhodes University, 2001. http://hdl.handle.net/10962/d1002495.
Pełny tekst źródłaWalther, Jallow Lilian. "Methods for detection of HIV-2/SIV infections /". Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4214-5/.
Pełny tekst źródłaPessane, Nilza. "Analysis of the impact of HIV/AIDS on civil society and a growing economy in Mozambique "Assessing aspects of democratic consolidation" /". Pretoria : [S.n.], 2010. http://upetd.up.ac.za/thesis/available/etd-02232010-142353.
Pełny tekst źródłaScherer, aus Pullach Patricia. "Diagnose HIV+ trauma oder chance? : das human immunodeficiency virus uns das acquired immune deficiency syndrome als "voodoo-formeln" der moderne /". München : Ludwig-Maximilians-Universität, 1996. http://catalog.hathitrust.org/api/volumes/oclc/38175768.html.
Pełny tekst źródłaPetoumenos, Kathy Public Health & Community Medicine Faculty of Medicine UNSW. "Treatment experience and HIV disease progression: findings from the Australian HIV observational database". Awarded by:University of New South Wales. School of Public Health and Community Medicine, 2006. http://handle.unsw.edu.au/1959.4/24937.
Pełny tekst źródłaBrennan, Erin Ann. "Stigmatization of HIV positive individuals". Click here for download, 2008. http://proquest.umi.com/pqdweb?did=1574154001&sid=1&Fmt=2&clientId=3260&RQT=309&VName=PQD.
Pełny tekst źródłaJames, Katherine Louise. "Viral genetics of HIV-2 infection". Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:68ba022d-62e4-4cb1-8032-085ea5240b98.
Pełny tekst źródłaCullen, Christine. "Understanding misperceptions about HIV and AIDS". Diss., Connect to the thesis, 2006. http://thesis.haverford.edu/154/01/2006CullenCEconomics.pdf.
Pełny tekst źródłaChohan, Bhavna H. "Characteristics of human immunodeficiency virus type-1 envelope at infection and reinfection in a cohort of Kenyan women /". Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/9304.
Pełny tekst źródłaMegazzini, Karen M. "Provision of rapid HIV testing and nevirapine administration in Zambian labor wards to improve population antiretroviral coverage of HIV-infected women and their HIV-exposed infants". Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2009r/megazzini.pdf.
Pełny tekst źródłaReid, Carol. "A randomised clinical trial to evaluate the effect of diet on quality of life of people living with HIV and lipodystrophy". Thesis, Queensland University of Technology, 2003. https://eprints.qut.edu.au/36787/2/36787_Digitised%20Thesis.pdf.
Pełny tekst źródłaWise, Daniel Lynn Goggin Kathy J. "Criminal penalties for non-disclosure of HIV-positive status effects on HIV testing rates and incidence /". Diss., UMK access, 2008.
Znajdź pełny tekst źródła"A dissertation in clinical psychology." Advisor: Kathleen J. Goggin. Typescript. Vita. Title from "catalog record" of the print edition Description based on contents viewed Sept. 12, 2008. Includes bibliographical references (leaves 127-136). Online version of the print edition.
Chigali, George M. "Assessment of the factors associated with HIV risk behaviours amongst women in Livingstone, Southern Province, Zambia". Thesis, University of the Western Cape, 2006. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_2551_1189600940.
Pełny tekst źródłaThe aim of this study was to assess the factors associated with HIV risk behaviours in women in Livingstone, Zambia. A cross-sectional analytical survey using a structured questionnaire was carried out in two sites in Livingstone, which were selected on the basis of differences in socio-economic status. Married women and women in the urban community are at high risk of contracting HIV and every effort should be made to ensure that HIV/AIDS programmes help to reduce their vulnerability to HIV infection.
Calitz, Margaretha. "The effect of an aerobic exercise program on the health-related quality of life of HIV-positive employees". Pretoria : [S.n.], 2009. http://upetd.up.ac.za/thesis/available/etd-10192009-145934/.
Pełny tekst źródłaKok, Tuckweng. "Early events in the replication cycle of human immunodeficiency virus /". Title page, contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phk79.pdf.
Pełny tekst źródłaCopy of author's previously published article on back end-paper. Includes bibliographical references (leaves 105-158).
GOURGEONNET, ALAIN. "Hypertrichose ciliaire acquise au cours des infections vih". Aix-Marseille 2, 1990. http://www.theses.fr/1990AIX20136.
Pełny tekst źródłaCarey, Catherine Louise. "Prospective memory in HIV-1 infection /". Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2005. http://wwwlib.umi.com/cr/ucsd/fullcit?p3170274.
Pełny tekst źródłaWhelan, Kathryn Theresa. "Dendritic cell function in HIV disease". Thesis, University of Oxford, 2003. http://ora.ox.ac.uk/objects/uuid:15b65f1c-4d92-48ec-bcab-aecc92dc674c.
Pełny tekst źródłaSpeelmon, Emily. "Innate mechanisms of HIV-1 protection in highly exposed, seronegative individuals /". Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/4998.
Pełny tekst źródłaHejdeman, Bo. "Studies on medical and immunological interventions in HIV-1 infection /". Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-019-2/.
Pełny tekst źródłaSmed, Sörensen Anna. "On the role of dendritic cells in HIV-1 infection /". Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-052-4/.
Pełny tekst źródłaWang, Bin. "Biological and molecular mechanisms in HIV disease progression and co-infection". Thesis, The University of Sydney, 2000. https://hdl.handle.net/2123/27745.
Pełny tekst źródłaHotchkiss, Graham. "Towards ribozyme-mediated gene therapy of HIV-1 infections /". Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4007-X/.
Pełny tekst źródłaRussell, Rodney S. "The influence of HIV-1 proviral burden on disease progression and response to antiretroviral therapy". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0015/MQ55539.pdf.
Pełny tekst źródłaLeonard, Erin. "Attachment, depression, and medication in adolescents with HIV infection". Click here for text online. The Institute of Clinical Social Work Dissertations website, 2007. http://www.icsw.edu/_dissertations/Leonard_2007.pdf.
Pełny tekst źródłaA dissertation submitted to the faculty of the Institute of Clinical Social Work in partial fulfillment for the degree of Doctor of Philosophy.