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1

Forward, SP, PJ McGrath, D. MacKinnon, TL Brown, J. Swann i EL Currie. "Medication Patterns of Recurrent Headache Sufferers: A Community Study". Cephalalgia 18, nr 3 (kwiecień 1998): 146–51. http://dx.doi.org/10.1046/j.1468-2982.1998.1803146.x.

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This community-based telephone survey determined medication patterns of 274 frequent headache sufferers who reported 12 or more headaches a year. Headaches were classified using the International Headache Society's (IHS) criteria. Participants reported on 465 types of headaches: 129 tension headaches, 158 migraine headaches, 8 chronic tension headaches, and 148 headaches which were unclassifiable using IHS criteria. Females ( n=133) reported an average of 1.9 types of headache and males ( n=141) reported 1.5 headache types. Fifty-six percent of respondents used acetaminophen for tension-type and 60% used acetaminophen for migraine. One percent used prescription medication for tension headache and 12% used prescriptions for migraine. The perceived effectiveness of over-the-counter medication was approximately 7 on a scale of 0–10 for tension headaches and 6 for migraine. Both tension-headache and migraine-headache sufferers waited about 1 h before taking any medication. Tension-headache sufferers waited until the headache was above 5 on a 0 to 10 scale (4.6 for migraine). It is possible that more aggressive use of medication might improve headache management.
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Djuric, Marija, Jasna Zidverc-Trajkovic, Nadezda Sternic, Jasna Trbojevic-Stankovic, Ivko Maric, Miodrag Milic i Biljana Stojimirovic. "Hemodialysis-related headaches". Vojnosanitetski pregled 64, nr 5 (2007): 319–23. http://dx.doi.org/10.2298/vsp0705319d.

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Background/Aim. Hemodialysis (HD) is a therapeutic procedure used to partially correct homeostatic disorders and prevent complications of uremia to appear in the terminal stage of renal insufficiency. The aim of this study was to evaluate and analyze the incidence and features of headaches in patients undergoing hemodialysis. Methods. A total of 143 patients, 50 women and 93 men, undergoing hemodialysis, were questioned about their problems with headache using a questionnaire designed according to the diagnostic criteria of the International Headache Classification of Headache Disorders from 2004. The patients were separated into two groups: the patients without headache and the patients with repeated headaches. Afterwards, the patients with headaches were further divided into subgroups: the patients who had the headaches before the beginning of HD and patients who experienced repeated headaches with the beginning of HD headache (HDH). In the group of patients with headaches we analyzed characteristics of headache according to which diagnoses of headaches were made, as well as the effects of HD on headaches. We also analyzed features of HDH. The patients with headache were compared to the patients without headache regarding sex, age, duration of HD, causes of end-stage renal disease, arterial diastolic and systolic blood pressure and serum concentration of hemoglobin, urea nitrogen, creatinine, sodium and potassium. The results were statistically compared. Results. In the group of 143 patients examined, 27 (18.9%) patients had headaches. There were no statistically significant differences between the group of patients with headaches and those without headache regarding to sex, age, duration of HD, causes of end-stage renal disease, serum concentration of hemoglobin, urea nitrogen, creatinine, sodium and potassium. The patients with headaches showed significantly higher mean values of systolic blood pressure during HD in comparison to the patients without headaches (p = 0.029). There was no statistically significant difference between the two groups regarding the mean values of diastolic blood pressure. Nineteen (13.3%) patients had had headache before starting HD. HD did not have any effect on the characteristics of headaches in more than a half of these patients. In 8 (5.6%) patients we diagnosed HDH using the diagnostic criteria of the International Headache Classification of Headache Disorders from 2004. HDH showed similar characteristics in all the patients: it appeared mostly in men, during the 4th hour of HD, lasted less than four hours, it was localized bilaterally in the frontal parts of the head, strong in intensity, throbbing and without the associated symptoms. Conclusion. The results of our study clearly showed that HDH was a particular entity of headache, not only because of its connection with HD, but because it had similar characteristics in all the patients in which it had appeared. Finding out the pathophysiological mechanisms of their occurrence would significantly improve the quality of life style of patients on hemodialysis. .
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De, Cadeo Chinh, i Hao Tam. "Unconventional Therapy on Headache from Anatomy and Physiology Standpoint". Journal of Asian Multicultural Research for Medical and Health Science Study 3, nr 2 (16.03.2022): 35–41. http://dx.doi.org/10.47616/jamrmhss.v3i2.263.

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This article discusses applied pharmacotherapy related to headaches and Gout. Headache is one of the frequently reported subjective complaints. Based on the causes, they are classified as primary headaches and secondary headaches. The aim of this paper is that students can know the definition of headache, know the classification of panic pain, know the anatomy and physiology of headache, know the prevention of headaches and adjunctive therapy and know the management for headaches.
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Аrtemenkо, Аda R., Olga A. Shavlovskaya, Vera V. Оsipovа, Gennadiy V. Kovrov i Rovshan L. Gasanov. "Sleep-related headaches: clinical features and treatment approaches". L.O. Badalyan Neurological Journal 1, nr 1 (19.04.2020): 35–46. http://dx.doi.org/10.17816/2686-8997-2020-1-01-35-46.

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Headaches occurring during sleep are one of the most common types of night time pain complaints, along with back pain. Sleep-related headaches can be a manifestation of both primary headaches (migraine, cluster headache, chronic paroxysmal hemicrania, hypnic headache) and secondary headaches associated with somatic pathology (anemia, hypoxemia), neurological disorders (brain tumors, arteriovenous malformations), psychiatric (depressive, anxiety) and sleep disorders (obstructive sleep apnea). The relationship between headaches and sleep depends on the patients age, frequency and severity of the headaches, provoking factors (excessive sleep, sleep deprivation, overuse of painkillers), the stage of sleep (REM sleep or slow-wave sleep) and possible genetic predisposition (hemiplegic migraine). The connections between sleep and headaches are complex and interrelated. Sleep can both provoke and relieve headaches. On the other hand, headaches can cause sleep disorders, which are typical for a severe type of cephalgia with the development of chronic daily headache syndrome, medication overuse, and psychiatric comorbidity. General anatomical structures, neurochemical and neurophysiological mechanisms involved in sleep and headache regulation are assumed. According to polysomnography data, objective changes in the structure of night sleep were detected in patients with a sleep-related headache: a reduction in the sleep duration and a decrease in the slow-wave sleep representation. Most nighttime headache attacks are linked with the REM sleep phase. Management of patients with sleep-related headaches should include the diagnosis and treatment of both headache and sleep disorder, which will significantly improve the results of treatment or even cure headaches in some cases.
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5

Haas, DC. "Chronic Post-Traumatic Headaches Classified and Compared with Natural Headaches". Cephalalgia 16, nr 7 (listopad 1996): 486–93. http://dx.doi.org/10.1046/j.1468-2982.1996.1607486.x.

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This study sought to determine whether chronic post-traumatic headaches are different from or identical to the naturally occurring headaches. The chronic post-traumatic headaches of 48 patients were classified, as if they were natural headaches, by the diagnostic criteria of the International Headache Society. Thirty-six patients' headaches (75%) were chronic tension-type headache, 10 (21%) were migraine without aura, and 2 (4%) were unclassifiable. The characteristics and accompaniments of the headaches within each diagnostic group were then compared to those in a control group with natural headaches of the same type. No notable differences between the post-traumatic and control groups were found. Hence, chronic post-traumatic headaches have no special features, but are symptomatically identical to either chronic tension-type headache or migraine without aura (in this series of patients). This identity suggests that post-traumatic headaches are generated by the same processes causing the natural headaches, not by intracranial derangement from head blows or jolts.
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6

Shulman, Stan. "Headaches, Headaches, Headaches". Pediatric Annals 34, nr 6 (1.06.2005): 425. http://dx.doi.org/10.3928/0090-4481-20050601-03.

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Souza, Delon D., Sonia Shivde, Poonam Awatare, Amrutha Avati, Saji K. John, Sagar Badachi, Raghunandan Nadig, GRK Sarma i Thomas Mathew. "Headaches associated with acute SARS-CoV-2 infection: A prospective cross-sectional study". SAGE Open Medicine 9 (styczeń 2021): 205031212110502. http://dx.doi.org/10.1177/20503121211050227.

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Objectives: The prevalence and characteristics of COVID-19-related headaches are not known in Indian patients. We aim to determine the prevalence and characteristics of headache in COVID-19-infected individuals and make a comparison with those without headaches. Methods: This prospective cross-sectional observational study was conducted from 1 October to 31 October 2020. Data were collected using a detailed questionnaire. We compared the data of those with and without headaches to identify the differences between the groups. Results: During the study period of 1 month, among 225 COVID-19-infected patients, 33.8% patients had headaches. The mean age of patients with headache was 48.89 ± 15.19 years. In all, 53.9% were females. In 65.8%, headache occurred at the onset of viral illness; 44.7% described the headache as dull aching; 39.5% had bifrontal headache; and 32.9% had holocranial headache. In total, 78.9% had complete resolution of headache within 5 days. A comparison between those with and without headaches showed that those with headaches were more younger (48.89 ± 15.19 vs 54.61 ± 14.57 years, p = 0.007) and of female gender (41/76(53.9%) vs 41/149 (27.5%), p = 0.001). Primary headache disorders were more common in the headache group. Levels of inflammatory markers such as leukocyte count (7234.17 ± 3054.96 vs 8773.35 ± 5103.65, p = 0.017), erythrocyte sedimentation rate (39.28 ± 23.29 vs 50.41 ± 27.61, p = 0.02) and ferritin (381.06 ± 485.2 vs 657.10 ± 863.80, p = 0.014) were lower in those with headaches. Conclusions: Headaches are a common and early symptom of acute SARS-CoV-2 infection more frequently seen in young females and in those with a history of primary headache disorders. The lower level of inflammatory markers in those with headaches suggests that these headaches are probably due to the local spread of virus through the trigeminal nerve endings, resulting in activation of the trigeminovascular system.
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8

Greenfield, Daniel P., i Subramanian Hariharan. "Diagnosis and Clinical Management of Headaches". CNS Spectrums 4, nr 9 (wrzesień 1999): 32–37. http://dx.doi.org/10.1017/s1092852900012153.

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AbstractIn this article, we will first present an overview of the epidemiology and classification of headaches, distinguishing between primary headaches (in which the headache itself is the primary disorder) and secondary headaches (ie, headaches due to an underlying condition, such as a neoplastic and/or space-occupying lesion, a cerebrovascular accident, or other type of structural brain lesion). We will use the current classification system of the International Headache Society, focusing on primary headache disorders (migraine, tension-type headache, cluster headache), which we will discuss from the practical clinical perspectives of diagnosis and clinical management. Throughout this article, we will emphasize the chronicity and periodicity of headaches as a type of chronic pain syndrome.
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González-Quintanilla, Vicente, Jorge Madera i Julio Pascual. "Update on headaches associated with physical exertion". Cephalalgia 43, nr 3 (14.02.2023): 033310242211469. http://dx.doi.org/10.1177/03331024221146989.

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Background Headaches associated with physical exertion include headache precipitated by coughing or other Valsalva maneuvers, headache brought on by prolonged physical exercise, sexual headaches and cardiac cephalalgia. Objective To review and update the clinical characteristics, etiologies, pathophysiology and management of these headaches related to exertion. Methods In depth review of the publications, both in PubMed and in the main textbooks, of the different headaches induced by physical exercise. Results Cough, exercise and sexual headaches can be primary or secondary; therefore, complementary studies are mandatory to rule out structural lesions. However, clinical characteristics, such as an old age and response to indomethacin for cough headache or being a young male and response to beta-blockers for exercise and sexual headaches, plus a normal examination are suggestive of a primary etiology. Etiology for secondary varieties, as posterior fossa lesions for cough headache or vascular malformations for exercise and sexual headaches, are also different. Finally, headache as a distant manifestation of myocardial ischemia, also known as “cardiac cephalalgia”, appears at exertion in around two-thirds of cases and typically lasts less than 30 minutes and is relieved by nitroglycerine. Conclusions Primary and secondary cough headache can usually be suspected based on clinical characteristics and separated from exercise and sexual headaches, which share many aspects. Cardiac cephalalgia is not necessarily an exertional headache and should be considered in adult patients with short lasting headaches and patent vascular risk factors.
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10

Selvakumar, Kiruthika. "THE EFFECT OF AEROBIC EXERCISES ON PAIN, QUALITY OF LIFE IN PRIMARY HEADACHE". Journal of Experimental Biology and Agricultural Sciences 9, Spl-1- GCSGD_2020 (25.03.2021): S01—S09. http://dx.doi.org/10.18006/2021.9(spl-1-gcsgd_2020).s01.s09.

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Headache disorders are among the most common disorders of the nervous system. According to World Health Organisation reports that almost half of all adults worldwide experience a headache in any given year. Based on research, headaches are classified into primary and secondary headaches. Depending on global prevalence the most common primary headaches are migraine, tension-type, and cluster headaches. If left untreated it can result in increased pain, decreased quality of life. The objective of this literature article is to analyze the effect of aerobic exercise on pain and quality of life among subjects with primary headaches like migraine, tension-type, and cluster headache and to discuss the current updates in the literature. In this article, relevant data available in PubMed, Cochrane, and Medline databases were retrieved from 2010 to February 2020 using the search terms aerobic exercise and tension-type headaches, aerobic exercise and migraine, aerobic exercise and cluster headaches, pain, and quality of life. The search strategy identified five articles that considered the effect of aerobic exercise on primary headaches like a migraine; tension-type and cluster. Results have positive effects for aerobic exercise on tension-type headache, migraine headache mainly on pain intensity, whereas the quality of life is less studied. On the other hand, these studies did not provide a specific protocol or parameter on exercise intensities. The availability of data on the influence of aerobic exercise on primary headaches though is limited, aerobic exercises are the best option for reducing pain and improving quality of life in primary headaches, especially for tension-type and migraine-type headaches.
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11

Sheftell, Fred, Mary Almas, Randall Weeks, Ninan T. Mathew, Verne Pitman i Richard B. Lipton. "Quantifying the return of headache in triptan-treated migraineurs: An observational study". Cephalalgia 30, nr 7 (17.03.2010): 838–46. http://dx.doi.org/10.1177/0333102409354390.

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To improve understanding of secondary treatment failure in migraine patients, we evaluated ‘headache return’ as a novel endpoint to assess returning headaches according to their severity, expanding on current standard assessments of overall recurrence or relapse rates, in a six-month observational study of triptan-treated migraineurs. A total of 359 patients (91% female; mean age, 42.5 years) recorded data for 2168 headaches in electronic diaries. Two-thirds of headaches responded to triptan treatment (improved-to-mild or no pain two hours post-dose); 34% of headaches had a pain-free response. By 48 hours post-dose, 19% of all responding headaches returned; 24% of headaches achieving a pain-free response returned, predominantly to mild pain. More severe baseline headache, short duration since diagnosis of migraine, and female gender were associated with increased likelihood of headache return. Treatment satisfaction declined with increasing severity of headache return, demonstrating the value of assessing headache return by severity to fully evaluate its impact.
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Lebedeva, Elena R., Anton V. Ushenin, Denis V. Gilev i Jes Olesen. "Clinical characteristics of persistent headaches after the first-ever ischemic stroke (follow-up of 529 patients)". Consilium Medicum 24, nr 11 (5.01.2023): 823–27. http://dx.doi.org/10.26442/20751753.2022.11.201974.

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Background. Although persistent headaches are a common post-stroke pain syndrome, the epidemiology and clinical features of persistent headache after first-ever ischemic stroke have not been considered previously. There is no exact data on how often headache attributed to stroke persists for more than 3 months, i.e. meets the criteria for persistent headache after stroke and what are their distinctive clinical features. The tasks of our study were: to analyze the occurrence/incidence of persistent headaches after the first-ever ischemic stroke; to determine clinical characteristics and types of persistent headaches in comparison with headaches at the onset of stroke. Materials and methods. The study included 550 patients (mean age 63.1 years, 54% men) with first-ever ischemic stroke, of which 529 patients were followed up for at least three months after the stroke. Standardized semi-structured interview forms were used to assess these headaches during professional face-to-face interviews at the onset of stroke and 3 months after the stroke using telephone interview by neurologist. Results. Among 529 follow up patients 55 (10.4%) had persistent headaches after first-ever ischemic stroke. Among these 55 patients 34 patients had persistent new-type headaches which arose for the first time during the onset of stroke, they included predominated migraine-like headaches (n=20), tension-type-like headaches (n=9) and thunderclap-like headaches (n=5). 21 patients had persistent headaches with altered characteristics: predominated tension-type-like headaches (n=16), and less common migraine-like headaches (n=5). Persistent headaches after stroke had the following characteristics compared to headaches at onset of stroke: severe headache intensity, a gradual decrease of occurrence of accompanying symptoms (photo- and phonophobia; p=0.03), the transition of unilateral headaches in bilateral (p=0.004), the presence of headaches 15 days per month in 30.9% of the patients. Conclusion. Persistent post-stroke headaches represent a persistent pain syndrome with severe intensity and frequency of attacks, which requires their further study and creation of guidelines for their management.
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He, Yunsen, Mengjun Zhang, Caiquan Huang, Xiaohong Qin, Zhou Zhang, Yishuang Wang, Lili Guo i in. "Prevalence and treatment of typical and atypical headaches in patients with Chiari I malformation: A meta-analysis and literature review". Cephalalgia 43, nr 1 (styczeń 2023): 033310242211313. http://dx.doi.org/10.1177/03331024221131356.

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Objective A meta-analysis was conducted to analyze the incidence of typical and atypical headaches and outcomes following various treatments in patients with Chiari I malformation. Background Headache is the most common symptom of Chiari malformation, which can be divided into typical and atypical subgroups to facilitate management. Much controversy surrounds the etiology, prevalence and optimal therapeutic approach for both types of headaches. Method We identified relevant studies published before 30 July 2022, with an electronic search of numerous literature databases. The results of this study were reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Result A total of 1913 Chiari malformation type I CIM patients were identified, 78% of whom presented with headache, within this group cephalgia was typical in 48% and atypical in 29% of patients, and migraine was the most common type of atypical headache. The ratio of typical/atypical headaches with international classification of headache disorders diagnosis was 1.53, and without international classification of headache disorders diagnosis was 1.56, respectively. The pooled improvement rates of typical headaches following conservative treatment, extradural decompression and intradural decompression were 69%, 88%, and 92%, respectively. The corresponding improvement rates for atypical headaches were 70%, 57.47%, and 69%, respectively. The complication rate in extradural decompression group was significantly lower than in intradural decompression group (RR, 0.31; 95% CI: 0.06–1.59, I2 = 50%, P = 0.14). Low reoperation rates were observed for refractory headaches in extradural decompression and intradural decompression groups (1%). Conclusion The International Classification of Headache Disorders can assist in screening atypical headaches. extradural decompression is preferred for typical headaches, while conservative therapy is optimal for atypical headaches. A definite correlation exists between atypical headaches and Chiari Malformation Type I patients with higher prevalence than in the general population. Importantly, decompression is effective in relieving headaches in this particular patient population.
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Greve, Esther, i Jesper Mai. "Cluster Headache-Like Headaches: A Symptomatic Feature?: A Report of Three Patients with Intracranial Pathologic Findings". Cephalalgia 8, nr 2 (czerwiec 1988): 79–82. http://dx.doi.org/10.1046/j.1468-2982.1988.0802079.x.

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This report concerns three patients with cluster headache-like headaches associated with intracranial pathologic findings. The question whether the occurrence of cluster headache-like headaches may be a symptomatic feature is still not solved. In two of the three presented cases the cluster headache-like headaches disappeared when the intracranial abnormalities were treated.
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Mohammadi, Nurallah, Marzyeh S. Sajadinejad, Mohammad R. Taghavi i Nahid Ashjazadeh. "Effects of Cognitive-Behavioral Group Therapy on Recurrent Headaches in Iranian Culture". Psychological Reports 103, nr 3 (grudzień 2008): 893–98. http://dx.doi.org/10.2466/pr0.103.3.893-898.

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This study investigated effects of applying cognitive-behavioral group therapy on recurrent headaches. Among Shiraz University female students complaining of headaches, 20 patients, each reporting either migraine or tension-type headaches and who met the 1988 International Headache Society diagnosis criteria for migraine and tension-type headaches, formed two groups. Analysis showed cognitive-behavioral group therapy decreased headache index significantly. Therapeutic response patterns on dependent variables were similar for patients with migraines and those with tension-type headaches.
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Metti, Andrea, Karen Schwab, Alan Finkel, Renee Pazdan, Lisa Brenner, Wesley Cole, Heidi Terrio i Ann I. Scher. "Posttraumatic vs nontraumatic headaches". Neurology 94, nr 11 (10.01.2020): e1137-e1146. http://dx.doi.org/10.1212/wnl.0000000000008935.

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ObjectiveTo describe and compare phenotypic features of posttraumatic headaches (PTH) and headaches unrelated to concussion.MethodsParticipants are a random sample of recently deployed soldiers from the Warrior Strong cohort, consisting of soldiers with (n = 557) and without (n = 1,030) a history of a recent mild traumatic brain injury (mTBI; concussion). mTBI+ soldiers were subdivided as PTH+ (n = 230) and PTH− (n = 327). Headache classification was based on a detailed phenotypic questionnaire. Medical encounters for headache were documented for the year after deployment.ResultsThe findings here are limited to the soldiers with headaches, consisting of 94% of the mTBI+ soldiers and 76% of the mTBI− soldiers. Other than headache duration, all headache/migraine features were more common or more severe in the PTH+ group compared to the nonconcussed group (mTBI−) and compared to the concussed group with nontraumatic headaches (PTH−). Headaches were largely similar in the mTBI− and PTH− groups. The features most specific to PTH+ included allodynia, visual aura, sensory aura, daily headache, and continuous headache. Medical consultation for headache was most common in the PTH+ group (62%) vs the PTH− group (20%) or the mTBI− group (13%) (p < 0.008).ConclusionsIn this cohort of recently deployed soldiers, PTHs are more severe, frequent, and migraine-like and more often associated with medical consultation compared to headaches presumed unrelated to concussion. Future observational studies are needed to verify and characterize the PTH phenotype, which could be followed by treatment trials with appropriate and possibly novel outcomes for prespecified subgroups.ClinicalTrials.gov identifierNCT01847040.
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Zwart, J.-A., G. Dyb, TL Holmen, LJ Stovner i T. Sand. "The Prevalence of Migraine and Tension-Type Headaches Among Adolescents in Norway. The Nord-Trøndelag Health Study (Head-Hunt-Youth), A Large Population-Based Epidemiological Study". Cephalalgia 24, nr 5 (maj 2004): 373–79. http://dx.doi.org/10.1111/j.1468-2982.2004.00680.x.

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The aim of this study was to examine the prevalence of headache and primary headache disorders like migraine and tension-type headaches among adolescents, and to explore the differences in headache prevalence and frequency by gender and age. This cross-sectional study was conducted in Nord-Trøndelag county, Norway, during the years 1995-97. In total, 8984 (88%) out of 10 202 invited adolescents aged 12-19 years participated in the youth part of the Nord-Trøndelag Health Study [Helseundersøkelsen i Nord-Trøndelag (HUNT)]. The total study population in this study consisted of 8255 individuals after exclusion of invalid questionnaires and students outside the target range of 13-18 years of age. The students completed a comprehensive questionnaire, and one of the questions was whether the students had experienced any headaches during the last 12 months. In addition, 5847 of these students were also subject to an interview in which they were asked whether they had experienced recurring headaches during the last year and, if so, were they classified as migraine (MI), tension-type headache (TTH) or non-classifiable headache. In the total questionnaire-based population, 76.8% reported having had headaches during the last 12 months (69.4% boys and 84.2% girls). Among those who also were interviewed, 29.1% reported having recurrent headaches (21.0% boys and 36.5% girls). The overall 1-year prevalence of migraine was 7%, of tension-type headache 18%, and of non-classifiable headache 4.8%. Higher prevalence rates were found for girls in all age groups and for all headache categories. The overall frequency of recurrent headaches did not vary significantly with age, but girls had significantly more frequent headaches than boys. We concluded that headache in general, and recurrent primary headache disorders like migraine and tension-type headaches, are common somatic complaints among Norwegian adolescents, especially among girls.
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Lupi, Chiara, Luana Evangelista, Valentina Favoni, Antonio Granato, Andrea Negro, Lanfranco Pellesi, Raffaele Ornello i in. "Rare primary headaches in Italian tertiary Headache Centres: Three year nationwide retrospective data from the RegistRare Network". Cephalalgia 38, nr 8 (12.05.2018): 1429–41. http://dx.doi.org/10.1177/0333102418768824.

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Background Rare primary headaches are mainly included in Chapters 3, Trigeminal autonomic cephalalgias, and 4, Other primary headache disorders, Part One of the International Classification of Headache Disorders 3rd edition. Epidemiological data are scarce, mostly emerging from case series or small studies, with the exception of cluster headache. In order to overcome the knowledge gap about rare primary headaches, the RegistRare Network was launched in 2017 to promote research in the field. Methods A retrospective cohort study including patients who, from April 30, 2014 to May 1, 2017, visited seven Italian tertiary Headache Centres, was undertaken to estimate in that clinical setting prevalence and incidence of headaches included in Chapters 3 and 4, Part One of the International Classification of Headache Disorders 3rd edition. Prevalent headache is defined as a headache recorded within the study timeframe, regardless of when the diagnosis was made. Incident headache is defined as a headache diagnosed for the first time in the patient during the study period. Results Twenty thousand and eighty-three patients visited the participating centres, and 822 (4.1%) prevalent cases, of which 461 (2.3%) were incident cases, were registered. Headaches listed in Chapter 3 affected 668 patients, representing 81.3% of the total number of prevalent cases. Headaches listed in Chapter 4 affected 154 patients and represent 18.7% of the total number of prevalent cases. Cluster headaches represent the most frequently diagnosed rare headaches (70.4%). For 13 entities out of 20, no cases were registered in more than 50% (n ≥ 4) of the centres, and for 14 entities more than 50% of diagnoses were incident. Conclusions This large, multicentre study gives the first wide-ranging snapshot of the burden in clinical practice of rare headaches and confirms that cooperative networks are necessary to study rare headaches, as their prevalence is often very low. The launch of a disease registry by the RegistRare Network will favour research in this neglected population of headache patients. Trial registration NCT03416114.
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Simić, Svetlana, Tamara Rabi-Žikić, José R. Villar, José Luis Calvo-Rolle, Dragan Simić i Svetislav D. Simić. "Impact of Individual Headache Types on the Work and Work Efficiency of Headache Sufferers". International Journal of Environmental Research and Public Health 17, nr 18 (22.09.2020): 6918. http://dx.doi.org/10.3390/ijerph17186918.

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Background: Headaches have not only medical but also great socioeconomic significance, therefore, it is necessary to evaluate the overall impact of headaches on a patient’s life, including their work and work efficiency. The aim of this study was to determine the impact of individual headache types on work and work efficiency. Methods: This research was designed as a cross-sectional study performed by administering a questionnaire among employees. The questionnaire consisted of general questions, questions about headache features, and questions about the impact of headaches on work. Results: Monthly absence from work was mostly represented by migraine sufferers (7.1%), significantly more than with sufferers with tension-type headaches (2.23%; p = 0.019) and other headache types (2.15%; p = 0.025). Migraine sufferers (30.2%) worked in spite of a headache for more than 25 h, which was more frequent than with sufferers from tension-type and other-type headaches (13.4%). On average, headache sufferers reported work efficiency ranging from 66% to 90%. With regard to individual headache types, this range was significantly more frequent in subjects with tension-type headaches, whereas 91–100% efficiency was significantly more frequent in subjects with other headache types. Lower efficiency, i.e., 0–40% and 41–65%, was significantly more frequent with migraine sufferers. Conclusions: Headaches, especially migraines, significantly affect the work and work efficiency of headache sufferers by reducing their productivity. Loss is greater due to reduced efficiency than due to absenteeism.
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Schwaiger, J., S. Kiechl, K. Seppi, M. Sawires, H. Stockner, T. Erlacher, ML Mairhofer i in. "Prevalence of Primary Headaches and Cranial Neuralgias in Men and Women Aged 55–94 Years (Bruneck Study)". Cephalalgia 29, nr 2 (luty 2009): 179–87. http://dx.doi.org/10.1111/j.1468-2982.2008.01705.x.

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The aim of the current study was to estimate the prevalence of all primary headaches and cranial neuralgias in the general community. As part of the population-based Bruneck Study, 574 men and women aged 55–94 years underwent extensive neurological and laboratory examinations involving a standardized headache interview. In the Bruneck Study population the lifetime prevalence of all primary headaches combined and of cranial neuralgias was 51.7 and 1.6%, respectively. Tension-type headache (40.9%) and migraine (19.3%) emerged as the most common types of headache. In men and women aged 55–94 years the 1-year prevalence of primary headaches was high at 40.5%. In this age range headaches caused significant impairment of health-related quality of life. The Bruneck Study has confirmed the high lifetime prevalence of primary headaches and cranial neuralgias in the general population and provided first valid prevalence data for all primary headaches based on International Classification of Headache Disorders, 2nd edition criteria.
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Toom, Kati, Aire Raidvee, Katri-Helena Allas, Elina Floria, Kristiina Juhkami, Gustav Klimušev, Maria Leping i in. "The prevalence of primary headache disorders in the adult population of Estonia". Cephalalgia 39, nr 7 (11.02.2019): 883–91. http://dx.doi.org/10.1177/0333102419829909.

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Objective To estimate the one-year prevalence of primary headaches, most importantly migraine and tension type headache, but also other primary headaches, in Estonia. Methods A population-based random sample of 2162 subjects in Tartu City and Tartu County were interviewed by telephone or face to face using a previously validated questionnaire. Results Of the 2162 contacted participants, 1215 (56%) fully completed the study. Of these, 502 (41.3%) reported headache during the previous year. The prevalences adjusted by weighting by age, gender, education, marital status and habitat were the following: All headaches 41.0%, all migraine 17.7%, all tension-type headache 18.0%, trigeminal autonomic cephalalgias 0.4%, other primary headaches 2.5%, and chronic headaches 2.7%. Conclusion The 1-year prevalences of primary headache disorders in Estonia are comparable to the previous findings in other European countries.
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Vishwanath, Mr Bite Rushikesh. "Preparation and Characterization Mustard Oil, Nutmeg and Cloves to Treat Headache". International Journal for Research in Applied Science and Engineering Technology 9, nr 12 (31.12.2021): 1290–98. http://dx.doi.org/10.22214/ijraset.2021.39526.

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Abstract: Headache is an extremely common symptom and collectively headache disorders are among the most common of the nervous system disorders, with a prevalence of 48.9% in the general population.1 Headache affects people of all ages, races and socioeconomic status and is more common in women. Some headaches are extremely debilitating and have significant impact on an individual’s quality of life, imposing huge costs to healthcare and indirectly to the economy in general. Only a small proportion of headache disorders require specialist input. The vast majority can be effectively treated by a primary care physician or generalist with correct clinical diagnosis that requires no special investigation. Primary headache disorders – Headaches, tension headache and cluster headache – constitute nearly 98% of all headaches; however, secondary headaches are important to recognise as they are serious and may be life threatening. This article provides an overview of the most common headache disorders and discusses the red flag symptoms that help identify serious causes that merit urgent specialist referral. The current pathway of headache care in the UK is discussed with a view to proposing a model that might fit well in the financially constrained National Health Service (NHS) and with new NHS reforms. The role of the national society, the British Association for the Study of Headache, and the patient organisations such as Headaches Trust in headache education to the professionals and the general public in shaping headache care in the UK is described. The article concludes by summarising evidence-based management of common headache diagnoses. Keywords: Headache, Headaches, tension headache, cluster headache, medication overuse headache
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Nowak, Aleksandra, Aleksandra Babicz i Mariusz Nowak. "Primary headache – causes and differential diagnosis". Pediatria i Medycyna Rodzinna 17, nr 4 (31.12.2021): 310–14. http://dx.doi.org/10.15557/pimr.2021.0049.

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It is estimated that 30–80% of the population in Europe and the United States experience frequent and recurrent headaches, the most common of which are tension-type, migraine and cluster headaches. Migraine can also overlap with tension-type headache, which is referred to as vasomotor or mixed headache. According to the 3rd edition of the International Classification of Headache Disorders (ICHD-3 beta), these entities are classified as idiopathic (primary) headaches, where pain is both the essence and the main symptom of the disease. Idiopathic headaches are difficult to diagnose as they differ mainly in intensity. When collecting medical history, the focus should be placed on the duration and location of pain. Therefore, a thorough interview to assess subjective pain intensity is one of the basic elements of the diagnostic workup. Tension-type headache, migraine and cluster headaches are also characterised by specific symptoms, identification of which is essential for the diagnosis. Cluster headache produces the most typical symptoms. Since these types of headaches require different therapeutic strategies, it is necessary to differentiate them. Their treatment requires interdisciplinary cooperation of, among others, dentists, neurologists, and physiotherapists. In this paper, we made an attempt to discuss the pathogenesis, symptoms and differential diagnosis of tension headache, migraine and cluster headache, based on literature review.
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Armini, Ni Wayan Yusi, i Diah Nirmala Dewi. "Hatha Yoga Sebagai Terapi Alternatif Pada Nyeri Kepala". JURNAL YOGA DAN KESEHATAN 4, nr 1 (31.03.2021): 76. http://dx.doi.org/10.25078/jyk.v4i1.2028.

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<p><em>Headaches often suddenly attack and this causes disruption to the various activities that are being carried out by ours. Headaches are pain in the head that can occur gradually or appear instantly almost unexpectedly. Headaches that appear can be felt light, heavy, and the area can be felt in the entire head or only in certain areas. There are many ways to deal with headaches, such as get some medication or get some massage therapy at certain points area, depending kind of headaches. However, the use of pain medication usually only has a short-term impact, so that at any time this headache reappears. Yoga therapy is an alternative in dealing with this headache. Yoga is indeed known as an alternative healing for certain diseases, one of them is headache. Although there is no exact and in-depth research on this issue, but some yoga movements are said to be able to deal with headaches, especially for those who often experience this headache attack at the wrong time, for example.</em></p>
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Constantinidis, Theodoros S., Chryssa Arvaniti, Nikolaos Fakas, Jobst Rudolf, Evangelos Kouremenos, Ermioni Giannouli i Dimos D. Mitsikostas. "A population-based survey for disabling headaches in Greece: Prevalence, burden and treatment preferences". Cephalalgia 41, nr 7 (1.02.2021): 810–20. http://dx.doi.org/10.1177/0333102421989630.

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Objective To estimate the prevalence, burden and current treatment of disabling primary headaches in a large sample of the Greek population aged 18–70 years old. Methods This is an observational descriptive study, with cross-sectional design performed by quantitative computer-assisted telephone interviews, using a validated 37-item questionnaire for headaches. The prevalence, burden, and current treatment of primary headaches (ICHD-3) were recorded along with participants’ treatment preferences. Results Out of 10,008 interviewed participants, 1197 (12.0%) reported headaches affecting performance. The annual prevalence of migraine was 8.1% (95% confidence interval, 7.6–8.7, corresponding to 0.6 million Greeks), of chronic migraine 1.0% (95% confidence interval, 0.8–1.2, corresponding to 0.1 million), and of tension-type headache 3.8% (95% confidence interval, 3.4–4.2, corresponding to 0.3 million). The participants with headaches reported 0.5 headache-induced lost workdays per month (corresponding to 5.8 million lost workdays annually) and reductions in performance on 2.8 workdays per month (corresponding to 30.9 million workdays annually). In all, 43.4% of headache participants felt bad/ashamed because of headaches and 21.9% sought professional treatment, most often from a private neurologist. 83.8% of headache participants had never taken pharmacological prophylaxis, and only 5.5% were currently under preventative treatment. For both prophylactic and acute treatment, headache participants prefer oral medication to injection or stimulation devices. Conclusion More than 10% of the Greek adult population up to 70 years old experience disabling headaches, causing a dramatic work loss. More than 80% of these have never taken pharmacological prophylaxis. Thus, enriching the quality of life of people with headaches relies crucially on expanding awareness about headaches and their treatment.
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Nur Muthmainnina, Auliya, i Shahdevi Nandar Kurniawan. "TENSION TYPE HEADACHE (TTH)". JPHV (Journal of Pain, Vertigo and Headache) 3, nr 2 (1.09.2022): 44–49. http://dx.doi.org/10.21776/ub.jphv.2022.003.02.4.

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Cerebrovascular disease is the number one cause of epilepsy in the elderly population. Headaches are relatively common in patients with cerebrovascular disorders. The frequency of stroke-related headaches ranges from 7% to 65% with different types of headaches. The prevalence of persistent post-stroke headaches from 7-23%, with follow-up times ranging from 3 months to 3 years after stroke. Persistent headache in the population was associated with high depression and fatigue scores and significantly impacted returning to work. Most headaches at stroke onset will resolve, persistent headaches are a real entity even years after the stroke. The mechanism that might explain the relationship between headache and hemorrhagic stroke is still unclear, including changes in blood vessel walls supported by endothelial dysfunction in migraine sufferers as well as comorbid vascular risk factors such as arterial hypertension or platelet dysfunction. Headache after stroke intracerebral hemorrhage is believed to be the result of vasoconstriction that causes ischemia of the vessel wall.
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Silva-Néto, Raimundo Pereira, Ânderson Batista Rodrigues, Dandara Coelho Cavalcante, Pedro Henrique Piauilino Benvindo Ferreira, Ema Pereira Nasi, Kamila Maria de Holanda Sousa, Mário Fernando Pietro Peres i Marcelo Moraes Valença. "May headache triggered by odors be regarded as a differentiating factor between migraine and other primary headaches?" Cephalalgia 37, nr 1 (30.09.2016): 20–28. http://dx.doi.org/10.1177/0333102416636098.

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Objectives The objective of this article is to characterize olfactory stimulation as a trigger of headaches attacks and differentiation between migraine and other primary headaches. Participants and methods The study was prospective and experimental, with comparison of groups. A total of 158 volunteers (73 men and 85 women) were diagnosed with primary headaches, according to the criteria of the International Classification of Headache Disorders, Third Edition (beta version) (ICHD-3β). The study was conducted by two examiners; one of them was assigned to diagnose the presence and type of primary headache, while the other was responsible for exposing the volunteers to odor and recording the effects of this exposure. Results Of the 158 volunteers with headache, there were 72 (45.6%) cases of migraine and 86 (54.4%) with other primary headaches. In both groups, there were differences in headache characteristics (χ2 = 4.132; p = 0.046). Headache attacks (25/72; 34.7%) and nausea (5/72; 6.9%) were triggered by odor only in patients with migraine, corresponding to 19.0% (30/158) of the sample, but in none with other primary headaches (χ2 = 43.78; p < 0.001). Headache occurred more often associated with nausea ( p = 0.146) and bilateral location ( p = 0.002) in migraineurs who had headache triggered by odor. Headache was triggered after 118 ± 24.6 min and nausea after 72.8 ± 84.7 min of exposure to odor. Conclusions The odor triggered headache attacks or nausea only in migraineurs. Therefore, headache triggered by odors may be considered a factor of differentiation between migraine and other primary headaches and this trigger seems very specific of migraine.
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Sjaastad, Ottar M., i Torbjørn A. Fredriksen. "Neck and headache—Do we see paths through the jungle? An overview and an hypothesis". Cephalalgia Reports 2 (1.01.2019): 251581631986304. http://dx.doi.org/10.1177/2515816319863045.

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Background and overview: It is widely accepted that cervicogenic headache (CEH) originates in the neck. In many circles, it is also accepted that neck–tongue syndrome belongs to the headaches that have their origin in the neck. For many headache researchers, the list: “headaches stemming from the neck” ends here. The objective of this overview was to explore the field and to determine whether there are grounds for adding other headaches to this list. Discussion: We suggest that headaches stemming from the neck possibly consist of five different subgroups: CEH, neck–tongue syndrome, tractor drivers’ headache, posterior headache subsequent to protracted neck-ache, and chronic paroxysmal hemicrania with mechanical attack precipitation. An overview of the clinical characteristics of each putative subgroup with comments is given.
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Chow, James M. "Rhinologic Headaches". Otolaryngology–Head and Neck Surgery 111, nr 3P1 (wrzesień 1994): 211–18. http://dx.doi.org/10.1177/01945998941113p109.

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From January 1, 1991, to June 30, 1992, 18 patients were identified as having rhinologic sources for their primary symptom of facial pain or headache. These 18 patients satisfied certain inclusion and exclusion criteria to identify the site of origin of the headaches or facial pains as coming from the nasal cavities or paranasal sinuses. The majority of these patients (12 patients) were determined to have a septal spur causing the facial pain or headache. Other identified causes included retention cysts (3 patients), mucosal contact points (2 patients), and a dehiscent infraorbital nerve (1 patient). Fifteen of these 18 patients (83%) were significantly improved or cured of their facial pain or headache after medical or surgical therapy. The 3 patients who had either a minimal improvement or no improvement in their facial pains or headaches included 1 patient with an area of mucosal contact between the middle turbinate and the bulla ethmoidalis and 2 patients with septal spurs. In summary, medical or surgical therapy can be beneficial in the treatment of patients with headaches or facial pains of rhinologic origin.
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Yu, Kimberley, i Madeline Chadehumbe. "A rare pediatric case of cluster headaches after cardiac catheterization in a patient with an isolated innominate artery". SAGE Open Medical Case Reports 9 (styczeń 2021): 2050313X2110236. http://dx.doi.org/10.1177/2050313x211023679.

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While cluster headaches are classified and considered a primary headache disorder, secondary causes of cluster headaches have been reported and may provide insight into cluster headaches’ potential pathophysiology. The mechanisms underlying this headache phenotype are poorly understood, and several theories have been proposed that range from the activation within the posterior hypothalamus to autonomic tone dysfunction. We provide a review of reported cases in the literature describing secondary causes after cardiac procedures. We will present a novel pediatric case report of a 16-year-old boy with an isolated innominate artery who presented with acute new-onset headaches 8 h following cardiac catheterization of the aortic arch with arteriography and left pulmonary artery stent placement. The headaches were characterized by attacks of excruciating pain behind the left eye and jaw associated with ipsilateral photophobia, conjunctival injection, rhinorrhea, with severe agitation and restlessness. These met the International Classification of Headache Disorders-3 criteria for episodic cluster headaches. The headaches failed to respond to non-steroidal anti-inflammatory medications, dopamine antagonists, and steroids. He showed an immediate response to treatment with oxygen. This unique case of cluster headaches following cardiac catheterization in a pediatric patient with an isolated innominate artery may provide new insight into cluster headaches’ pathogenesis. We hypothesize that the cardiac catheterization induced cardiac autonomic changes that contributed to the development of his cluster headaches. The role of aortic arch anomalies and procedures in potential disruption of the autonomic tone and the causation of cluster headaches is an area requiring further study.
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Sklar, Frederick H., Laszlo Nagy i Brian D. Robertson. "The use of abdominal binders to treat over-shunting headaches". Journal of Neurosurgery: Pediatrics 9, nr 6 (czerwiec 2012): 615–20. http://dx.doi.org/10.3171/2012.2.peds11146.

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Object Headaches are common in children with shunts. Headaches associated with over-shunting are typically intermittent and tend to occur later in the day. Lying down frequently makes the headaches better. This paper examines the efficacy of using abdominal binders to treat over-shunting headaches. Methods Over an 18-year period, the senior author monitored 1027 children with shunts. Office charts of 483 active patients were retrospectively reviewed to identify those children with headaches and, in particular, those children who were thought to have headaches as a result of over-shunting. Abdominal binders were frequently used to treat children with presumed over-shunting headaches, and these data were analyzed. Results Of the 483 patients undergoing chart review, 258 (53.4%) had headache. A clinical diagnosis of over-shunting was made in 103 patients (21.3% overall; 39.9% of patients with headache). In 14 patients, the headaches were very mild (1–2 on a 5-point scale) and infrequent (1 or 2 per month), and treatment with an abdominal binder was not thought indicated. Eighty-nine patients were treated with a binder, but 19 were excluded from this retrospective study for noncompliance, interruption of the binder trial, or lack of follow-up. The remaining 70 pediatric patients, who were diagnosed with over-shunting headaches and were treated with abdominal binders, were the subjects of a more detailed retrospective study. Significant headache improvement was observed in 85.8% of patients. On average, the patients wore the binders for approximately 1 month, and headache relief usually persisted even after the binders were discontinued. However, the headaches eventually did recur in many of the patients more than a year later. In these patients, reuse of the abdominal binder was successful in relieving headaches in 78.9%. Conclusions The abdominal binder is an effective, noninvasive therapy to control over-shunting headaches in most children. This treatment should be tried before any surgery is considered. It is suggested that the abdominal binder may modulate abnormally increased intracranial pulse pressures associated with over-shunting. Interactions with the cerebrovascular bed are suspected to account for persistent headache relief after the binder is discontinued.
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Britze, Josefine, Nanna Arngrim, Henrik Winther Schytz i Messoud Ashina. "Hypoxic mechanisms in primary headaches". Cephalalgia 37, nr 4 (4.05.2016): 372–84. http://dx.doi.org/10.1177/0333102416647037.

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Background Hypoxia causes secondary headaches such as high-altitude headache (HAH) and headache due to acute mountain sickness. These secondary headaches mimic primary headaches such as migraine, which suggests a common link. We review and discuss the possible role of hypoxia in migraine and cluster headache. Methods This narrative review investigates the current level of knowledge on the relation of hypoxia in migraine and cluster headache based on epidemiological and experimental studies. Findings Epidemiological studies suggest that living in high-altitude areas increases the risk of migraine and especially migraine with aura. Human provocation models show that hypoxia provokes migraine with and without aura, whereas cluster headache has not been reliably induced by hypoxia. Possible pathophysiological mechanisms include hypoxia-induced release of nitric oxide and calcitonin gene-related peptide, cortical spreading depression and leakage of the blood-brain barrier. Conclusion There is a possible link between hypoxia and migraine and maybe cluster headache, but the exact mechanism is currently unknown. Provocation models of hypoxia have yielded interesting results suggesting a novel approach to study in depth the mechanism underlying hypoxia and primary headaches.
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Brigham, Christopher R. "Legal Update: Using the Guides for Permanent Partial Disability Determinations". Guides Newsletter 2, nr 2 (1.03.1997): 6. http://dx.doi.org/10.1001/amaguidesnewsletters.1997.marapr04.

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Abstract Rating the impairment related to various chronic painful conditions, including headaches, is challenging and is addressed in the AMA Guides to the Evaluation of Permanent Impairment (AMA Guides) in a section of the chapter on pain. Primary headache disorders include migraines, tension-type headaches, and cluster headaches caused by disturbances in the central nervous system. Headaches occur with varying intensities and frequencies but follow three broad patterns: 1) minimal, slight, moderate, and marked headache; 2) cycles or episodes that may last from moments to years; and 3) consistent and persistent pain that may last years, decades, or a lifetime. Physicians should estimate impairment related to headache pain according to the procedures discussed in section 15.8, including a multidimensional assessment of an individual's capabilities, including biological, psychological, and social aspects and excluding the existence of a separate comorbid pathologic process. The AMA Guides does not provide specific numeric values for impairment of headache or for pain itself. For patients who have a primary headache disorder, the physician should clearly understand the frequency and severity of the condition, the approach to treatment, and the effects of headaches on activities of daily living. The discussion of headaches in the AMA Guides emphasizes the importance of careful evaluation over merely assigning a numeric value to an impairment.
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Martin, Paul R., Paula R. Nathan i Dan Milech. "The Type A Behaviour Pattern and Chronic Headaches". Behaviour Change 4, nr 2 (czerwiec 1987): 33–39. http://dx.doi.org/10.1017/s0813483900008470.

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This article describes three studies that explore the relationship between headaches and the Type A behaviour pattern. The results of the first study demonstrated that in a student sample individuals who suffer from more fequent headaches and headaches of higher intensity have significantly elevated Type A scores. The second study complemented the first by showing that the majority of chronic headache sufferers displayed the Type A behaviour pattern; and the findings of the two studies together suggested that between 68% and 90% of chronic headache sufferers may be classified as Type A's. The results of the third study indicated that individuals whose headaches tended to be associated with negative affect (depression, anxiety, hostility, tiredness, confusion and unsureness) had significantly higher Type A scores than individuals whose headaches tended not to be associated with negative affect. It was suggested that the Type A behaviour pattern is a risk factor for headaches (as well as coronary heart disease and other disorders) as it resulted in the frequent experience of stress and negative affect which in turn could lead to headaches. Also, Type A individuals probably responded to headaches with more distress than those not exhibiting this behavioural style so that they were more likely to become trapped in the stress-headache spiral.
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Susanti, Restu. "POTENTIAL GENDER DIFFERENCES IN PATHOPHYSIOLOGY OF MIGRAINE AND TENSION TYPE HEADACHE". Human Care Journal 5, nr 2 (25.05.2020): 539. http://dx.doi.org/10.32883/hcj.v5i2.749.

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<p><em>Headache is one of the most common symtomps which cause patients consult a neurologist. Primary headache is headache without other underlying diseases. Primary headaches can be divided into migraine headaches, tension</em><em> </em><em>types-headache, trigeminal autonomic cephalalgias, and other types of headaches. Sex differences play a role in the perception of headache. Theories regarding hormonal, the number of pain-sensitive points, subjectivity, and psychosocial factors are mostly related to the differences of migraine and TTH pathophysiology between women and men.</em></p>
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Suzuki, Keisuke, Yasuyuki Okuma, Tomoyuki Uchiyama, Masayuki Miyamoto, Ryuji Sakakibara, Yasushi Shimo, Nobutaka Hattori i in. "The prevalence, course and clinical correlates of migraine in Parkinson’s disease: A multicentre case-controlled study". Cephalalgia 38, nr 9 (26.10.2017): 1535–44. http://dx.doi.org/10.1177/0333102417739302.

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Background Previous studies have reported a lower migraine prevalence in Parkinson’s disease (PD) patients and improvements in migraine headaches after PD onset, but the clinical association of migraines with PD is unclear. Methods We analysed headache and migraine prevalence and clinical correlates in 436 PD patients (mean age, 69.3 ± 7.8 years) and 401 age- and sex-matched controls (mean age, 69.2 ± 8.6 years) in a case-controlled, multicentre study. Migraines were diagnosed by a questionnaire developed according to the International Classification of Headache Disorders, second edition. We evaluated changes in headache intensity, frequency and severity over several years around the onset of PD among PD patients with headaches or migraines, and over the past several years among control subjects with headaches or migraines. Results PD patients had lower lifetime (9.6% vs. 18.0%) and 1-year (6.7% vs. 11.0%) migraine prevalences than controls. However, lifetime (38.5% vs. 38.9%) and 1-year (26.1% vs. 26.2%) headache prevalence did not differ between PD patients and controls. After adjusting for gender, timing of the evaluation of headache changes, and recall period, PD patients with headaches or migraines exhibited a pronounced reduction in the intensity, frequency and overall severity of their headaches and migraines after the onset of PD compared with controls with headaches or migraines. PD patients with migraines exhibited a higher rate of depression and higher Pittsburgh Sleep Quality Index and PD sleep scale-2 scores than those without headaches. Conclusion While overall headache and migraine severity reduced after PD onset, the presence of migraines was associated with sleep disturbances and depression in PD patients.
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Nowaczewska, Magdalena, Michał Wiciński, Stanisław Osiński i Henryk Kaźmierczak. "The Role of Vitamin D in Primary Headache–from Potential Mechanism to Treatment". Nutrients 12, nr 1 (17.01.2020): 243. http://dx.doi.org/10.3390/nu12010243.

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Some studies have suggested a link between vitamin D and headache; however, the underlying physiological mechanisms are unclear. We aimed to summarize the available evidence on the relationship between vitamin D and the various subtypes of primary headaches, including migraines and tension-type headaches. All articles concerning the association between primary headache and vitamin D published up to October 2019 were retrieved by searching clinical databases, including: EMBASE, MEDLINE, PubMed, Google scholar, and the Cochrane library. All types of studies (i.e., observational, cross-sectional, case-control, and clinical trials) were included. We identified 22 studies investigating serum vitamin D levels in association with headaches. Eight studies also evaluated the effect of vitamin D supplementation on the various headache parameters. Among them, 18 studies showed a link between serum vitamin D levels and headaches, with the strongest connection reported between serum vitamin D levels and migraine. Overall, there is not enough evidence to recommend vitamin D supplementation to all headache patients, but the current literature indicates that it may be beneficial in some patients suffering headaches, mainly migraineurs, to reduce the frequency of headaches, especially in those with vitamin D deficiency.
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Riahta, Naomi, Muhammad Ali, Bistok Saing, Yazid Dimyati i Johannes Saing. "Quality of life in adolescents with primary headaches". Paediatrica Indonesiana 53, nr 6 (30.12.2013): 350. http://dx.doi.org/10.14238/pi53.6.2013.350-4.

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Background Headaches are common problems in adults,adolescents, and children. Headaches impact a child's life, theirfamily life, and even society. An assessment of quality of life inadolescents with primary headaches may help to determine actionsnecessary to improve the quality of life of these patients.Objective To assess the quality oflife of adolescents with primaryheadach es compared to healthy adolescents.Methods We conducted a cross-sectional study in December2009 on adolescents aged 13 to 18 years. The headache groupconsisted of children with primary headaches according to theInternational Classification of Headache Disarders and the controlgroup consisted of healthy adolescents. Subjects were selected byconsecutive sampling, with 75 subjects in each group. Subjectsfilled the Pediatric Quality of Life Inventary version 4.0 (PedsQL4.0) questionnaire.Results The mean PedsQL total score was significantly lowerin the headache group than in the contra 1 group [ l 7 5. 7 vs.392.2, respectively, (95%CI of differences -28.l to -219.3, P =0.001)]. However, out of23 items in the questionnaire, 9 werenot significantly different between the headache and controlgroups.Conclusions Primary headaches in adolescents is associatedwith lower quality of life. Most quality of life domains scoresare significantly lower in adolescents with primary headachescompared to those without primary headaches.
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Knezevic-Pogancev, Marija. "Recurrent headache and migraine heritability: Twin study". Genetika 43, nr 3 (2011): 595–606. http://dx.doi.org/10.2298/gensr1103595k.

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The aim of the study was to determine recurrent headache (migraine and non-migraine) heritability, among the twin pairs. Headache hritability was investigated among 396 twin pairs (42.4% monozygotic and 57.6% dizygotic) aged 3 to 21 years, on north part territory of Serbia-Vojvodina, during the 20 years period. Within the group of tested twin persons, 30.2% had recurrent headaches, 9.2% migraine headache and 21% other recurrent non-migraine headaches. Heritability quotient of all recurrent headaches was 0.3882. For non- migraine headaches heritability quotient of 0.2286 confirmed that the external factors influence is higher than heritability. Migraine headache heritability quotient 0.8598 clearly proved the heritability of the migraine headache. Both, correlation and determination quotient of the migraine headache of all the twins (r12 0.7498; r21256.12%), monozygotic (r120.8458; r1271.54%) and dizygotic (r120.6342; r21240.22%), show high degree of migraine headache twin siblings dependence, and higher correlation and significance of the difference with monozygotic twins.
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Kaur, Amrit, Linda Selwa, Gail Fromes i Donald A. Ross. "Persistent Headache after Supratentorial Craniotomy". Neurosurgery 47, nr 3 (1.09.2000): 633–36. http://dx.doi.org/10.1097/00006123-200009000-00020.

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ABSTRACT OBJECTIVE Although the incidence, possible causes, and treatment of persistent headache after suboccipital craniotomy have been discussed extensively, few data have been published regarding persistent headache after supratentorial craniotomy. METHODS We retrospectively analyzed the senior author's patient series of 145 consecutive anterior temporal lobectomies for intractable epilepsy performed during a 9-year period. To eliminate confounding causes of headache, all patients studied were seizure-free, none had progressive mass lesions or persisting vascular anomalies, and none had major complications of surgery. With the permission of the institutional review board, information on headache was obtained from patient records, the patients' neurologists, and the patients themselves. RESULTS Of the 145 consecutive patients who underwent operations, 126 patients had adequate follow-up for analysis. Of the 126 patients, 104 did not have headaches and were not using regular analgesics 2 months postoperatively. Twenty-two patients had headaches persisting beyond 2 months. Seven (5.6%) of the 126 patients had headaches that lasted more than 2 months but less than 1 year, and they were free of recurrent headaches 1 year postoperatively. Fifteen (11.9%) of the 126 patients had ongoing headaches 1 year after surgery. Regarding headache severity, 4.0% of patients had medically uncontrolled headaches, and 3.2% continued to require prescription drugs for headaches 1 year postoperatively. CONCLUSION Although the incidence of persistent head pain after supratentorial craniotomy is lower than that reported for posterior fossa procedures, the incidence is not trivial. The cause of persistent pain deserves further investigation.
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Cingi, Cemal, Erdem Atalay Cetinkaya, Osman Halid Cam, Fatih Oghan i Nuray Bayar Muluk. "Use of codeine and NSAID combination in rhinogenic headache". Romanian Journal of Rhinology 9, nr 36 (1.12.2019): 165–69. http://dx.doi.org/10.2478/rjr-2019-0021.

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Abstract Headache is a common complaint which otolaryngologists frequently have to evaluate and treat in practice. Migraine, tension, cluster and sinus-rooted headaches are the most confronted ones in primary visits. Therefore, considerations of multidiscipline may be required to diagnose the rhinogenic and non-rhinogenic headaches. Rhinogenic headache is a distinct type of headache that has attracted an increased amount of attention in the recent years. The mechanism of headache is not yet known. In fact, the treatments of the above-mentioned headaches are different, but they may intersect in some cases. Non-steroid anti-inflammatory drugs (NSAID) and opioids are often used in headache treatment. Codeine, a well-known opioid derivative, has been prescribed for analgesia for a long time. This review aims to discuss the possible use and efficiency of NSAID and codeine combinations in the treatment of rhinogenic headaches.
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Li, Li, i Shengyuan Yu. "Heroin-induced headache in female heroin addicts". Journal of International Medical Research 48, nr 6 (czerwiec 2020): 030006052092535. http://dx.doi.org/10.1177/0300060520925353.

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Objective To investigate the manifestations and incidence of headaches caused by heroin in Chinese women. Methods This was a survey study conducted from 29 June to 3 July 2015 with women attending the Shanxi Drug Rehabilitation Centre for Women (China). All study subjects were newly admitted and had not begun their drug rehabilitation. Demographic characteristics, heroin usage and headache episodes within the previous 3 months were surveyed, especially the presence of a headache within 2 hours of heroin use. Details of the severity, location, premonitory symptoms and characteristics of headaches were recorded. Results Of the 90 heroin-dependent patients, 74 experienced headache attacks within 2 hours of heroin use, and the headaches subsided within 72 hours of discontinuation of heroin use. Most heroin-induced headaches were similar to migraines and manifested as pulsating pain in 54 patients (51/74, 68.9%); bilateral pain was reported by 46 patients (46/74, 62.2%). Approximately half of the patients with heroin-induced headaches also reported accompanying symptoms of nausea, vomiting, and light and sound sensitivity. Conclusions Heroin-induced headache may eventually be listed as a new class of headache in the International Classification of Headache Disorders.
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Leone, M., AP Cecchini, E. Mea, V. Tulio i G. Bussone. "Epidemiology of Fixed Unilateral Headaches". Cephalalgia 28, nr 1_suppl (lipiec 2008): 8–11. http://dx.doi.org/10.1111/j.1468-2982.2008.01607.x.

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A fixed location unilateral headache suggests involvement of a precise nervous structure, and neuroimaging investigations are essential to seek to identify it. Nevertheless, side-locked primary headaches also occur, although they are rare. Side-locked primary headaches are more frequently found in the group of the short-lasting (≤ 4 hours) headaches but long-lasting headache forms may also present with the pain always on the same side, including migraine, tension-type headache, new daily persistent headache and cervicogenic headache. Future studies should address the issue whether patients with side-locked headache form differ from those with non-side-locked form both in terms of natural history and biological markers. Among 63 consecutive chronic cluster headache patients seen by us from 1999 to 2007, 32 (51±) had side shift. We also found that the duration of the chronic condition was significantly longer in those with side shift than those without. The high frequency of side shift in chronic cluster headache should be considered when proposing surgical treatment for severe intractable forms of the disease.
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Peres, Mario Fernando Prieto, Daniel Diniz Gonçalves Lerário, Arthur Belarmino Garrido i Eliova Zukerman. "Primary headaches in obese patients". Arquivos de Neuro-Psiquiatria 63, nr 4 (grudzień 2005): 931–33. http://dx.doi.org/10.1590/s0004-282x2005000600005.

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BACKGROUND AND OBJECTIVE: Obesity is a major public health problem worldwide. Little is known about the prevalence and impact of headache disorders in obese patients. The objective of this study was to assess the prevalence of primary headaches in obese patients and controls. METHOD: Seventy-four consecutive obese patients from the obesity surgery service were studied, and compared to controls with body mass index less than 25. RESULTS: Fifty-six patients (75%) had a headache diagnosis, 49 migraine (66%), 7 tension-type headache (9%), 36 (48%) had incapacitating headaches. CONCLUSION: Primary headaches are more common and incapacitating in obese patients than controls, migraine is the most important diagnosis in this population. Headaches should be properly diagnosed and treated in obese patients.
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Vitta, Alberto de, Rangel dal Bello Biancon, Guilherme Porfírio Cornélio, Thiago Paulo Frascareli Bento, Nicoly Machado Maciel i Priscila de Oliveira Perrucini. "Primary headache and factors associated in university students: a cross sectional study". ABCS Health Sciences 46 (8.03.2021): e021207. http://dx.doi.org/10.7322/abcshs.2020005.1793.

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Introduction: Primary headaches, defined as disorders in themselves caused by independent pathomechanisms and not by other disorders, are prevalent in university students and considered one important health problems in the world. Objective: To investigate the prevalence of primary headaches and analyze associations with sociodemographic characteristics and the use of electronic devices by university students. Methods: A cross-sectional observational study analysis was carried out with a sample of 1,143 students of both genders who responded to the questionnaire on demographic, socioeconomic aspects, use of electronic devices, and on the primary headaches. Descriptive analysis, bivariate analysis, and Poisson regression were performed. Results: The overall prevalence of primary headache of 60.7%, being that, in relation to the type, 33.2% presented tension-type headache, 54.3% migraine, and 12.3% other types of headache. Regression analysis showed that female gender and income of up to two minimum wages were associated with primary headache and migraine type. The primary headache was associated with subjects of the white race; watching television and playing video games for more than 3 hours per day, for example. The sitting posture, semi-lying down, and distance from the eyes to the mobile phone and tablet longer than 20 cm were associated with primary headache and the three types of headaches. Conclusion: The results allow us to conclude that there is a high prevalence of primary headaches in college students and that socioeconomic factors related to the use of electronic devices are associated with the presence of primary headaches.
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Aykutlu, E., B. Baykan, G. Akman-Demir, B. Topcular i M. Ertas. "Headache in Behçet's Disease". Cephalalgia 26, nr 2 (luty 2006): 180–86. http://dx.doi.org/10.1111/j.1468-2982.2005.01017.x.

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The aim of this study was to investigate the characteristics of headache in patients with Behçet's disease (BD) seeking neurological consultation. Consecutive patients with BD seen within 1 year at the neuro-Behçet's out-patient clinic were studied using an electronic database according to the classification criteria of the International Headache Society. During a 12-month period 118 BD patients were admitted, and 98 had headaches. Migraine was the most common type of primary headache diagnosed in 45 patients (46.4%) in the whole headache group, followed by tension-type headache (TTH) in 26 cases (26.8%). Thirty-seven patients had secondary headaches mainly due to cerebral venous thrombosis or parenchymal neurological involvement of BD. Of these patients, 15 had both primary and secondary headaches. The primary headaches of 13 patients were exacerbated with systemic BD flare-ups, and four patients had migraine attacks triggered only by systemic BD activation which showed a good response to the treatment of systemic inflammation. The majority of the headaches of patients with BD do not indicate any neurological involvement; they are usually due to migraine or TTH. In a minority of patients, migraine associated with systemic inflammation of BD is notable.
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Mantia, L. La, D. D’Amico, A. Rigamonti, N. Mascoli, G. Bussone i C. Milanese. "Interferon treatment may trigger primary headaches in multiple sclerosis patients". Multiple Sclerosis Journal 12, nr 4 (sierpień 2006): 476–80. http://dx.doi.org/10.1191/1352458506ms1298oa.

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Recent data have suggested that interferon-b (IFN-β) may aggravate headaches in multiple sclerosis (MS) patients. The aim of this study was to investigate the life-time prevalence of primary headaches in MS patients treated with interferons in comparison with patients treated with other disease-modifying agents. Attention was focused on the onset of headache and the changes in pre-existing headaches in relation to the onset of therapy. The study was open-labelled and not randomized. We studied 150 consecutive MS patients treated with IFN-β (109 patients: 54 with 1b, 55 with 1a) and with other drugs (41 patients: 14 with glatiramer acetate, 27 with azathioprine). All patients underwent a semi-structured interview to diagnose headache type, according to the International Headache Society criteria. The frequency of primary headaches was higher in the interferon-group (72%) compared to patients in the other group (54%) ( P = 0.03). Worsening of pre-existing headaches or development of de novo headache occurred only in the interferon-group (41 and 48%, respectively) and not in the other group ( P<0.001). These results show that headache should be considered among the side-effects of interferon in MS patients.
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Iskra, D. A., V. Yu Lobzin i S. A. Kalygin. "Primary headaches and cognitive disorders — pathophysiologically associated and comorbidity conditions." V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY, nr 2 (11.11.2018): 97–103. http://dx.doi.org/10.31363/2313-7053-2018-2-97-103.

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Primary headaches (migraine, tension-type headache and other primary headaches) cause 3% of all disability cases in adult population, fully decrease possibilities of social functioning. Te phenomenon of the central sensitization is one of the fundamental pathophysiological units of primary headaches. NMDA receptors are involved both in initiation and in maintaining of mechanisms of a long-term central sensitization. NMDA activation by glutamate play important role in the initiation of primary headaches. Cognitive impairment development also conducted with NMDA-excitotoxicity due to hyper excitability of NMDA receptors. Tus, it is evident that mechanisms of antinociceptive changes in primary headaches and development of a glutamate excitotoxicity are strongly interdependent. Relationship between somatic symptoms, such as headache in dementia and cognitive symptoms now is represented more widely than just a comorbidity. Te gravity of migraine, tension-type headache and severity of cognitive impairment are strongly connected. Tus, the reliable interrelation between development of primary headache and cognitive decrease is traced, considering a community of pathophysiological mechanisms that has important practical value due to possible correction by NMDA-antagonists. Memantine not only slows the progression of cognitive symptoms in dementia, but also signifcantly influences the frequency and expressiveness of primary headache.
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Neß, Verena, Anna Könning, Gerrit Hirschfeld i Julia Wager. "Adolescents’ Explanatory Models for Headaches and Associations with Behavioral and Emotional Outcomes". Children 8, nr 3 (18.03.2021): 234. http://dx.doi.org/10.3390/children8030234.

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More than one-third of adolescents experience recurrent headaches. Usually, these headaches are of primary origin and modulated by different biological and psychosocial factors. While parents are often consulted in scientific research and medical care about the nature of their child’s headache, it is unclear to what extent parents and their children agree upon the factors that cause them. Adolescents’ own attributions of headaches have rarely been investigated, and it is unclear how those attributions affect behavioral and emotional outcomes. In the present study, adolescents with chronic headaches (N = 248) and their parents (N = 120) rated the influence of various biological and psychosocial factors on the adolescents’ headaches. Associations between these factors and several behavioral and emotional outcomes were examined. The most frequently reported factor by both samples was stress; however, concordance between parents and adolescents was generally low. The factor “other disease” was significantly associated with medication consumption and school absence. This study is one of the first to provide insights into adolescents’ own attributions of headaches. Furthermore, the significant associations of the factor with behavioral outcomes reveal the importance of understanding personal explanatory models of headache. Future studies should examine associations between subjective headache causes and the individual’s experience of the disorder to improve headache interventions.
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Chansoria, Mayank, Neha Vyas, Mamta Mahobia i Rita Upadhyay. "Headache, Primary Headaches and Their Treatment". Journal on Recent Advances in Pain 3, nr 2 (2017): 99–104. http://dx.doi.org/10.5005/jp-journals-10046-0078.

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