Rozprawy doktorskie: „HDE MODEL”

1

Billah, Baki 1965. "Model selection for time series forecasting models". Monash University, Dept. of Econometrics and Business Statistics, 2001. http://arrow.monash.edu.au/hdl/1959.1/8840.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

2

Jiráková, Eliška. "Investování v ČR ve vztahu k HDP". Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-17021.

Pełny tekst źródła

Streszczenie:

Investment has undergone dramatic development lately and people are looking more and more new ways to evaluate their funds to protect them from the effects of inflation or as easy to get rich This work deals with investment opportunities for Czechs in relation to their income and appreciation in relation to the welfare of the country measured by GDP. The first part describes the history of investment and investment opportunities. Subsequently, the work deals with the development of GDP and of the allocation of funds in various investment instruments in the development of GDP. The last part is devoted to modeling the development of further investment on GDP in the CR.

Style APA, Harvard, Vancouver, ISO itp.

3

Bispo, Vanderson da Silva. "Investigação dos mecanismos biológicos de detoxificação de aldeídos α,β- insaturados em ratos SODG93A modelo para ALS". Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/46/46131/tde-07122015-105825/.

Pełny tekst źródła

Streszczenie:

A lipoperoxidação gera diversas espécies carbonílicas altamente reativas dentre as quais se destacam acroleína (ACR), malondialdeído (MDA), 4-hidroxi-2-hexenal (HHE) e 4-hidroxi-2-nonenal (HNE). A principal via endógena de metabolização desses compostos é através de conjugação com glutationa por ação da glutationa-S-tranferase. Contudo, diversos trabalhos têm mostrado que dipeptídeos contendo histidina, tal como a carnosina (CAR), também podem formar conjugados com aldeídos e auxiliar na detoxificação desses compostos. Em nosso trabalho adutos de CAR com ACR, HHE, HHEd5, HNE e HNEd11 foram sintetizados, purificados e caracterizados. A reação da CAR com ACR foi estudada em detalhes. Resultados mostraram que a carnosina reage com acroleína formando 03 produtos principais: m/z = 265, m/z = 283 e m/z = 303, sendo este último mais estável e mais abundante. Dados de RMN H1, COSY e HSQC permitiram elucidar a estrutura dessa molécula (m/z = 303) e propor uma rota de reação. Em seguida, uma metodologia baseada em cromatografia líquida acoplada à espectrometria de massas do tipo \"Ion Trap\" (ESI+ HPLC/MS-MS) foi desenvolvida e validada para quantificação simultânea dos adutos sintetizados. Pelo método desenvolvido é possível quantificar com precisão 25 pmol de CAR-HHE, 1 pmol de CAR-ACR e 1 pmol de CAR-HNE com um coeficiente de variação de aproximadamente 10 % e acurácia de 98 % (HHEd5 e HNEd11 foram usados como padrão interno). Análise em urina de adultos não fumantes mostraram que os produtos sintetizados estão presentes na urina de humanos em concentrações de 3,6 ± 1,4; 2,3 ± 1,5 e 1,3 ± 0,5 nmol / mg de creatinina, respectivamente para CAR-ACR, CAR-HHE e CAR-HNE. Em ratos transgênicos SODG93A modelo para esclerose lateral amiotrófica (ELA), a suplementação da dieta dos animais com 35 ± 5 mg carnosina/animal/semana melhorou a manutenção do peso e a sobrevida dos animais. Análises dos adutos sintetizados em amostras de músculo sugerem que a metabolização de aldeídos esteja comprometida nesses animais e que a carnosina poderia funcionar como \"scavenger\" para esses compostos. Esses resultados comprovam que dipeptídeos de histidina atuam na detoxificação de compostos carbonílicos e participa de suas vias de excreção. Além disso, a caracterização da estrutura e desenvolvimento de método sensível de detecção abre a possibilidade de utilização desses adutos como biomarcadores de estresse redox e exposição a aldeídos.
Lipid peroxidation generates reactive carbonyl species, including 4-hydroxy-2-nonenal (HNE), acrolein (ACR), 4-hydroxy-2-hexenal (HHE) and malondialdehyde (MDA). One major pathway of aldehyde detoxification in vivo is through conjugation with glutathione catalyzed by glutathione-S-transferases or, alternatively, by conjugation with endogenous histidine containing dipeptides, such as carnosine (CAR). The reaction of CAR with ACR was investigated in an effort to assess its possible biological role. One stable adduct was isolated by reverse-phase HPLC and characterized on the basis of extensive spectroscopic measurements. The proposed reaction route for product formation involves the reaction of the CAR amino group with ACR via a Schiff base formation followed by dehydration and cyclization through Michael addition in the imidazole ring forming an instable compound with m/z = 265. The subsequent reaction with another molecule of ACR followed by cyclization gives rise to the final product with m/z = 303.A highly sensitive method involving HPLC-MS analysis was developed for the simultaneous accurate quantification of CAR- ACR, CAR-HHE and CAR-HNE adducts in human urinary samples from non-smoking adults. This methodology permits quantification of 10 pmol CAR-HHE and 1 pmol of CAR-ACR and CAR-HNE. Adduct levels in urine were 3.6 ± 1.4, 2.3 ± 1.5, 1.3 ± 0.5 nmol/mg of creatinine, respectively to CAR-ACR, CAR-HHE and CAR-HNE. In SODG93A transgenic rats model to amyotrophic lateral sclerosis (ALS), the food supplementation of the animals with 35 ± 5 mg carnosine/animal/week improve de body weight and the life span of the ALS treated group. Analysis of the synthesized adducts in muscle sample showed suggest than aldehyde metabolization is compromised in this animals and that may be carnosine work like a scavenger for these compounds. Our results indicate that carnosine adduction can be an important detoxification route of α,β -unsaturated aldehydes. Moreover, carnosine adducts quantification may be useful as redox stress indicator in vivo.

Style APA, Harvard, Vancouver, ISO itp.

4

Yoon, Jai-Hyung. "Four essays on international real business cycle and asset pricing models". Monash University, Dept. of Accounting and Finance, 2002. http://arrow.monash.edu.au/hdl/1959.1/8520.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

5

Leung, Yin-Ling. "Surface studies of planar model HDN catalysts". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ34576.pdf.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

6

Carter, Robert C. (Robert Charles) 1950. "The macro economic evaluation model (MEEM) : an approach to priority setting in the health sector". Monash University, Dept. of Management, 2001. http://arrow.monash.edu.au/hdl/1959.1/8672.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

7

Wang, Xiaojing. "Cost- benefit Models for HDV Platooning". Thesis, KTH, Skolan för elektro- och systemteknik (EES), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-200533.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

8

Lindström, Robin. "HDV Simulink Real World Model for Testing : A Study on Model Simplicity". Thesis, KTH, Optimeringslära och systemteori, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-188915.

Pełny tekst źródła

Streszczenie:

The purpose of this thesis was to investigate the area of model complexity and see what precautions could be made to avoid the generation of complex models. These findings included five principles stated by M. Pidd which were implemented in the development of a new Simulink real world model of a heavy duty vehicle. The developed model was integrated into a hardware-in-the-loop configuration and parameterized and validated by comparing the new model to the previous model in several advanced emergency brake test cases. Additional testing was done to prove the overall robustness and validity of the new model. With an average relative error of 2% compared to measurement data of the previous model and the additional testing considered passed, the new model was deemed valid and representative of a heavy duty vehicle. The study recommends that further simplifications are done in the hardware integration framework, which have not been targeted in this thesis, to reduce the complexity of the overall model further. All and all the new model met the deliveries and due to its less complex structure and maintained validity it was implemented at the REVT department at Scania CV AB.
Syftet med det här examensarbetet var att undersöka ämnet modell komplexitet och se vilka åtgärder som kan vidtas för att undvika skapandet av komplexa modeller. Studien inkluderar fem principer skrivna av M. Pidd vilka implementerades i skapandet av en ny Simulink omvärldsmodell av ett tungt fordon. Den utarbetade modellen integrerades i ett hardware-in-the-loop ramverk och parametriserades och validerades genom att jämföra den nya modellen mot den gamla i ett flertal testfall för den avancerade nödbromsen. Ytterligare tester genomfördes även för att bekräfta hållbarheten och giltigheten hos den nya modellen. Med ett snitt relativt fel på 2 % jämfört med mätdata från den tidigare modellen och godkänt resultat från de ytterligare testerna, ansågs den nya modellen vara en giltig och representativ avbild av ett tungt fordon. Studien rekommenderar att ytterligare förenklingar görs på hårdvaruramverket, som inte har berörts i det här arbetet, för att reducera komplexiteten hos modellen i helhet ytterligare. Överlag så levde modellen upp till alla krav och på grund av dess reducerade komplexa struktur och bibehållna giltighet, implementerades den på REVT avdelningen på Scania CV AB.

Style APA, Harvard, Vancouver, ISO itp.

9

Bieliková, Nikol. "Průměrná mzda a HDP - vzájemné vztahy a vazby". Master's thesis, Vysoká škola ekonomická v Praze, 2013. http://www.nusl.cz/ntk/nusl-198019.

Pełny tekst źródła

Streszczenie:

The thesis describes interactions and relationships between selected economic indicators. These indicators are the gross domestic product and the average gross monthly wage. The analysis of these selected indicators, are made for the Czech Republic and Slovakia. The work has four main parts, which are divided into several other sections. The first defines the concept of national accounting, the second part contents gross domestic product, the method of its calculating and the frequency of compilation. In the third section is described the field theory of wages and salaries and the concepts such as minimum wage, the average gross monthly wage and median wage and salary are defined. In this two chapters are compared selected countries on the basis of the tables and graphs of selected indicators. The last chapter analyzes the relationships between selected economic indicators in selected countries based on quarterly data from the years 2001-2013.

Style APA, Harvard, Vancouver, ISO itp.

10

Choudhary, Niket Kumar. "A Synthesizable HDL Model for Out-of-Order Superscalar Processors". NCSU, 2009. http://www.lib.ncsu.edu/theses/available/etd-07082009-161145/.

Pełny tekst źródła

Streszczenie:

Many contemporary servers, personal and laptop computers, and even cell phones are powered by high-performance superscalar processors. In the past, conventional microarchitecture and technology scaling has afforded leaps in their performance and functionality. Today, conventional microarchitecture and technology scaling are both yielding lower returns with increasing costs. Therefore, any microarchitecture level decision to increase performance needs to be critically analyzed from a technology standpoint. To address this critical need, we have developed a register transfer level (RTL) model of a superscalar microarchitecture with similar complexity of a current generation processor. The RTL model is written in Verilog and is fully synthesizable. The model can be implemented in different technology nodes using a well established ASIC design flow to provide high fidelity estimation of propagation delay, power consumption, area, and other technology related costs. The RTL model is supplemented with a register file compiler to estimate the costs of multi-ported memory structures which are extensively used in a superscalar microarchitecture. The RTL model is also tightly integrated with a C++ functional simulator to assist and accelerate verification.

Style APA, Harvard, Vancouver, ISO itp.

11

Anastasius, Malcolm Octavian. "A novel model for the evaluation of human HDL function". Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/20209.

Pełny tekst źródła

Streszczenie:

Background High-density lipoprotein (HDL) mediates macrophage reverse cholesterol transport (RCT). This process leads to decreased atherosclerotic plaque formation and progression. A causal relationship between HDL levels and CVD has been challenged, requiring investigation of HDL function independent of HDL levels. Whilst an ex vivo assay to measure the first step of RCT has been developed, a model to evaluate the capacity of human HDL to enhance in vivo macrophage RCT is lacking. Methods and Results This thesis investigated the application of a validated assay of macrophage RCT in the apolipoproteinA-I knockout (apoa1-/-) mouse, a model that has low background levels of HDL and RCT. These experiments show for the first time, that: 1) human HDL injection in apoa1-/- mice resulted in a dose-dependent appearance of human HDL in plasma and stimulation of macrophage RCT; 2) Human HDL modified with myeloperoxidase is impaired in enhancing RCT, validating the model for detection of HDL dysfunction; 3) HDL from acute coronary syndrome patients (ACS-HDL) demonstrated impaired RCT; 4) An ex vivo assay, using a cell line expressing the main receptor for HDL lipid uptake, scavenger receptor B type 1 (SR-B1), showed impaired SR-B1 receptor mediated uptake of lipid from ACS-HDL supporting defective hepatic SRBI-mediated lipid uptake as a mechanism for this dysfunction; 5) The ability of human HDL to promote ex vivo ABCA1-specific cellular cholesterol efflux, is not retained following mice injection; 6) serum CEC of mice injected HDL is not a good indicator of ex vivo HDL cholesterol efflux. Conclusion The thesis presents a novel model for the evaluation of human HDL function. HDL functionality does vary between patients, and simple evaluation of HDL concentration is limited in its ability to reflect HDL biology in vivo. These results also indicate that two simple, widely used assays of HDL function- HDL efflux and CEC- give incomplete insight into HDL function.

Style APA, Harvard, Vancouver, ISO itp.

12

Becker, Virgínia Esther Gueller. "Aplicação do modelo de Tavakoli para gerência de manutenção de pavimentos em cidade de médio porte". Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/3/3138/tde-18062013-155806/.

Pełny tekst źródła

Streszczenie:

Este trabalho foi realizado com o objetivo de aplicar o Modelo de Tavakoli, que é um modelo de gerência de pavimentos para vias urbanas, para análise de priorização de vias urbanas em cidade de médio porte. Para isso se utilizou um estudo de campo previamente realizado pela Prefeitura Municipal de Suzano e pelo Laboratório de Mecânica de Pavimentos da Universidade de São Paulo no município de Suzano, no ano de 2007, com o qual foi criado um banco de dados das vias do município. Naquele estudo foi empregado o modelo HDM-4 do Banco Mundial para a priorização de intervenções de manutenção nas vias públicas. No presente trabalho buscou-se elaborar um estudo comparativo entre aquela solução e a solução atingida pelo modelo de Tavakoli para um mesmo conjunto de vias. Para este trabalho o Modelo de Tavakoli foi adaptado para planilhas eletrônicas e aplicado em um conjunto de seções de pavimentos, permitindo a determinação de uma lista de prioridades de intervenções. Posteriormente, essas intervenções foram simuladas para o mesmo conjunto de vias, buscando a priorização dos serviços, com o modelo HDM-4 versão 1.0. Através deste trabalho foi possível concluir que os dois critérios estudados podem ser úteis para gerenciar vias urbanas, pois priorizaram as intervenções necessárias nas vias urbanas analisadas. Foi possível verificar que o Modelo de Tavakoli se revelou mais conservador, por ser um critério fechado, com um índice de prioridades dependendo diretamente do índice da condição do pavimento e do volume diário médio de tráfego, afetando diretamente a classificação das seções. No Modelo HDM-4 a classificação das seções e os valores de irregularidade não tiveram uma sincronia, pois o HDM-4 é um modelo de critérios abertos, que permite ao usuário acrescentar vários parâmetros, e com estes foi possível reproduzir uma situação um pouco mais próxima da realidade.
This study was conceived in order to apply the Tavakoli Model, which is a pavement management system for urban roads, aiming the analysis of prioritization of urban streets in a mid-sized city. A field study previously conducted by Suzano City and the Pavements Mechanics Laboratory of the University of São Paulo in Suzano City in 2007 was used, from which was created a database of the towns streets. In that study, the Highway Design and Management (HDM-4) Model of the World Bank was employed for prioritizing maintenance work on public roads. In this study it was sought to develop a comparative study between the mentioned solution and the one reached by Tavakolis Model in the same set of roads. In this research the Tavakoli Model was adapted for the spreadsheets and applied to a set of pavement sections, allowing the determination of a priority list of interventions including the specific type of intervention for each segment. Subsequently, these same types of strategies or interventions were simulated for the same set of paths, seeking the prioritization, with HDM-4 Model version 1.0. Through this research it was possible to conclude that both criteria studied can be useful for managing urban roads, because they prioritized the necessary interventions in the urban roads analyzed. The Tavakoli Model proved to be more conservative, on account of being a closed criterion, with a priority index depending directly on the pavement condition index and average daily volume of traffic, affecting the classification of the sections directly as well. In the HDM-4 Model, the classification of the sections and values of the International Roughness Index did not match, due to HDM-4 being an open criteria model, which allows the user to add several parameters, and they can lead to more realistic report.

Style APA, Harvard, Vancouver, ISO itp.

13

ROCCO, A. GUERINI. "IN SILICO STUDIES ON MODELS OF SYNTHETIC HDL". Doctoral thesis, Università degli Studi di Milano, 2008. http://hdl.handle.net/2434/51223.

Pełny tekst źródła

Streszczenie:

The major protein components of high-density lipoproteins (HDL) are apolipoprotein (apo) A-I and apoA-II. Sixty-three different mutations of apoA-I are known. Among them, apoA-IMilano (IM) and apoA-IParis (IP) are characterized by an R-C substitution, leading to the formation of disulfide-linked homodimers and of heterodimers with apoA-II. From observations in humans and in animal models apoA-IM and apoA-IP behave as molecules with an intrinsic antiatherogenic activity. No experimental structure at atomic resolution of lipid-bound apoA-I is available. In this thesis I present four molecular models of synthetic HDL containing a lipidic core of palmitoyloleoyl- phosphatidylcholine and either two molecules of wild type apoA-I, or one apoA-IM homodimer, or one apoA-IP homodimer, or two molecules of apoA-IM–apoA-II heterodimer. On all the systems I computed molecular dynamics simulations to obtain reliable data about the behavior of apoA-I in a lipidic environment and to sharpen the understanding of its molecular functions in regulating cholesterol homeostasis. In all the four models of s- HDL the increase with time in the number of favorable interactions between apoA-I and phospholipids was the driving force for the structural reorganization and stabilization of s-HDL. I found a strong correspondence between computed and experimental properties, which supports the reliability of my results.

Style APA, Harvard, Vancouver, ISO itp.

14

Tong, C. O. (Chung On) 1945. "A schedule-based transit network model". Monash University, Dept. of Civil Engineering, 1986. http://arrow.monash.edu.au/hdl/1959.1/7935.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

15

Dong, Yuanyuan. "A visual attention model for high dynamic range (HDR) video content". Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/51777.

Pełny tekst źródła

Streszczenie:

High dynamic range (HDR) imaging is gaining widespread acceptance in computer graphics, photography and multimedia industry. Representing scenes with values corresponding to real-world light levels, HDR images and videos provide superior picture quality and more life-like visual experience than traditional 8-bit Low Dynamic Range (LDR) content. In this thesis, we present a few attempts to assess and improve the quality of HDR using subjective and objective approaches. We first conducted in-depth studies regarding HDR compression and HDR quality metrics. We show that High Efficiency Video Coding (HEVC) outperforms the previous version of compression standard on HDR content and could be used as a platform for HDR compression if provided with some necessary extensions. We also find that, compared to other quality metrics, the Visual Information Fidelity (VIF) quality metric has the highest correlation with subjective opinions on HDR videos. These findings contributed to the development of methods that optimize existing video compression standards for HDR applications. Next, the viewing experience of HDR content is evaluated both subjectively and objectively. The study shows a clear subjective preference for HDR content when individuals are given a choice between HDR and LDR displays. Eye tracking data were collected from individuals viewing HDR content in a free-viewing task. These eye tracking data collected are utilized in the development of a visual attention model for HDR content. Last but not least, we propose a computational approach to predict visual attention for HDR video content, the only one of its kind as all existing visual attention models are designed for HDR images. This proposed approach simulates the characteristics of the Human Visual System (HVS) and makes predictions by combining the spatial and temporal visual features. The analysis using eye tracking data affirms the effectiveness of the proposed model. Comparisons employing three well known quantitative metrics show that the proposed model substantially improves predictions of visual attention of HDR.
Applied Science, Faculty of
Electrical and Computer Engineering, Department of
Graduate

Style APA, Harvard, Vancouver, ISO itp.

16

Sparks, Matthew A. "A COMPREHENSIVE HDL MODEL OF A LINE ASSOCIATIVE REGISTER BASED ARCHITECTURE". UKnowledge, 2013. http://uknowledge.uky.edu/ece_etds/26.

Pełny tekst źródła

Streszczenie:

Modern processor architectures suffer from an ever increasing gap between processor and memory performance. The current memory-register model attempts to hide this gap by a system of cache memory. Line Associative Registers(LARs) are proposed as a new system to avoid the memory gap by pre-fetching and associative updating of both instructions and data. This thesis presents a fully LAR-based architecture, targeting a previously developed instruction set architecture. This architecture features an execution pipeline supporting SWAR operations, and a memory system supporting the associative behavior of LARs and lazy writeback to memory.

Style APA, Harvard, Vancouver, ISO itp.

17

Allen, Matthew S. "Performance Assessment of Model-Driven FPGA-based Software-Defined Radio Development". Digital WPI, 2014. https://digitalcommons.wpi.edu/etd-theses/943.

Pełny tekst źródła

Streszczenie:

"This thesis presents technologies that integrate field programmable gate arrays (FPGAs), model-driven design tools, and software-defined radios (SDRs). Specifically, an assessment of current state-of-the-art practices applying model-driven development techniques targeting SDR systems is conducted. FPGAs have become increasingly versatile computing devices due to their size and resource enhancements, advanced core generation, partial reconfigurability, and system-on-a-chip (SoC) implementations. Although FPGAs possess relatively better performance per watt when compared to central processing units (CPUs) or graphics processing units (GPUs), FPGAs have been avoided due to long development cycles and higher implementation costs due to significant learning curves and low levels of abstraction associated with the hardware description languages (HDLs). This thesis conducts a performance assessment of SDR designs using both a model-driven design approach developed with Mathworks HDL Coder and a hand-optimized design approach created from the model-driven VHDL. Each design was implemented on the FPGA fabric of a Zynq-7000 SoC, using a Zedboard evaluation platform for hardware verification. Furthermore, a set of guidelines and best practices for applying model-driven design techniques toward the development of SDR systems using HDL Coder is presented."

Style APA, Harvard, Vancouver, ISO itp.

18

Fukuda, Masakazu. "Spontaneous Reconstitution of Discoidal HDL from Model Membranes by Apolipoprotein A-I". 京都大学 (Kyoto University), 2010. http://hdl.handle.net/2433/120516.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

19

Carter, Tiffany. "Hemostatic efficiency of amphiphilic peptide solution in Wistar Rat model". Thesis, Kansas State University, 2014. http://hdl.handle.net/2097/35239.

Pełny tekst źródła

Streszczenie:

Master of Science
Department of Grain Science and Industry
X. Susan Sun
One of the leading causes of death following traumatic injury is exsanguination. The body addresses bleeding through the process of hemostasis which includes the formation of a fibrin mesh structure that holds a blood clot together. During traumatic injury, hemostasis may be unable to stop excess bleeding. Fibrin based hemostatic agents have been developed, however, these studies often use fibrin obtained from biological sources, which poses risk of infection. A novel amphiphilic peptide (h9e) has been studied to form three dimensional nanofibers networks. In this research, we studied the ability to form a synthetically produced, fibrin-mimic, hemostatic material from the h9e peptide sequence. The objective of this study was to determine the blood gelation strength of the h9e peptide necessary to arrest bleeding in the Wistar Rat model. Commercial mouse blood was used for blood gelation in vitro studies. Dynamic rheometer was used to determine the gelation kinetics at varied h9e peptide concentrations ranging from 1-5% wt. By directly mixing the h9e peptide with blood, we observed that the blood gelation strength right after mixing increased as the h9e peptide weight % concentration increased, from 67 to 1086 Pascals in the peptide concentration from 1 to 5%, respectively. After 24 hours, final gelation strength of all concentrations with commercial mouse blood was lower than the instantaneous strength but consistent throughout testing. Similar testing was conducted using commercial Wistar Rat blood with weight % concentrations of 1, 3, and 5% of h9e peptide. The gelation strength was 500, 1665, and 1914 Pascals, respectively. We also determined the gelation strength of Wistar Rat blood components, such as red blood cells, serum, and plasma with 1% h9e peptide. We observed the gelation response induced with individual blood components; however, the strength is weaker than whole blood. In vivo, we applied the cut-tail method by dipping the cut-tail of Wistar Rats into the h9e peptide solutions for 10 seconds and then took it out for blood lost collection. We observed that h9e peptide solution at 1, 3, and 5% weight concentrations can all generate hemostatic function. The h9e peptide solution at 5% weight concentration (1914 Pa) was able to outperform a commercial hemostatic material (Moore Medical CELOX* Hemostatic Granules), significantly reducing both bleeding time and blood lost: h9e peptide at 5% had a bleeding time of 94 sec and 0.75 mL blood lost, while the Celox hemostatic granules had a bleeding time of 225 sec and 1.5 mL blood lost. Transmission Electron Microscopy and Spinning Disk Confocal Microscope imaging indicated a blood component reinforced, web-like, h9e nanofiber structure similar to the structure formed by fibrin in a blood clot. This study showed that h9e peptide has the potential to be used to induce hemostasis.

Style APA, Harvard, Vancouver, ISO itp.

20

Le, Truc. "Stochastic volatility models". Monash University, School of Mathematical Sciences, 2005. http://arrow.monash.edu.au/hdl/1959.1/5181.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

21

Tissainayagam, Prithiviraj 1967. "Visual tracking : development, performance evaluation, and motion model switching". Monash University, Dept. of Electrical and Computer Systems Engineering, 2001. http://arrow.monash.edu.au/hdl/1959.1/8944.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

22

Nguyen, Thuy-Linh 1964. "An object-oriented data model for evolvable Web systems". Monash University, School of Computer Science and Software Engineering, 2000. http://arrow.monash.edu.au/hdl/1959.1/9008.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

23

Shami, Roland G. (Roland George) 1960. "Bayesian analysis of a structural model with regime switching". Monash University, Dept. of Econometrics and Business Statistics, 2001. http://arrow.monash.edu.au/hdl/1959.1/9277.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

24

OKUMA, Shigeru, Tatsuya SUZUKI, YoungWoo KIM i Tatsuya KATO. "Model Predictive Control of Traffic Flow Based on Hybrid System Modeling". Institute of Electronics, Information and Communication Engineers, 2005. http://hdl.handle.net/2237/14988.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

25

Pitrun, Ivet 1959. "A smoothing spline approach to nonlinear inference for time series". Monash University, Dept. of Econometrics and Business Statistics, 2001. http://arrow.monash.edu.au/hdl/1959.1/8367.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

26

Hoang, Tam Minh Thi 1960. "A joint probability model for rainfall-based design flood estimation". Monash University, Dept. of Civil Engineering, 2001. http://arrow.monash.edu.au/hdl/1959.1/8892.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

27

Weier, Annette 1960. "Demutualisation in the Australian life insurance industry". Monash University, Dept. of Economics, 2000. http://arrow.monash.edu.au/hdl/1959.1/8371.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

28

Azam, Mohammad Nurul 1957. "Modelling and forecasting in the presence of structural change in the linear regression model". Monash University, Dept. of Econometrics and Business Statistics, 2001. http://arrow.monash.edu.au/hdl/1959.1/9152.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

29

Bailey, Mark A(Mark Alexander) 1970. "Improved techniques for the treatment of uncertainty in physically-based models of catchment water balance". Monash University, Dept. of Civil Engineering, 2001. http://arrow.monash.edu.au/hdl/1959.1/8271.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

30

Zhao, Haiyan. "Catalytic Hydrogenation and Hydrodesulfurization of Model Compounds". Diss., Virginia Tech, 2009. http://hdl.handle.net/10919/26526.

Pełny tekst źródła

Streszczenie:

This dissertation describes two related studies on hydrogenation and hydrodesulfurization of heterocyclic S-containing compounds. Alkyl substituted thiophenes are promising candidates for hydrogen carriers as the dehydrogenation reactions are known to occur under mild conditions. Four types of catalysts including supported noble metals, bimetallic noble metals, transition metal phosphides and transition metal sulfides have been investigated for 2-methylthiophene (2MT) hydrogenation and ring opening. The major products were tetrahydro-2-methylthiophene (TH2MT), pentenes and pentane, with very little C5-thiols observed. The selectivity towards the desired product TH2MT follows the order: noble metals > bimetallics > phosphides > sulfides. The best hydrogenation catalyst was 2% Pt/Al2O3 which exhibited relatively high reactivity and selectivity towards TH2MT at moderate temperatures. Temperature-programmed desorption (TPD) of hydrogen indicated that the H2 desorption amount was inversely related to the rate of TH2MT formation. Temperature programmed reaction (TPR) experiments revealed that pentanethiol became the major product, especially with HDS catalysts like CoMoS/Al2O3 and WP/SiO2, which indicates that poisoned or modified conventional HDS catalysts would be good candidates for further 2MT hydrogenation studies. The role of tetrahedral Ni(1) sites and square pyramidal Ni(2) sites in Ni2P hydrotreating catalysts was studied by substitution of Ni with Fe. The Fe component was deemed as a good probe because Ni2P and Fe2P adopt the same hexagonal crystal structure, yet Fe2P is completely inactive for hydrodesulfurization (HDS). For this purpose a series of NiFeP/SiO2 catalysts were prepared with different Ni:Fe molar ratios (1:0, 3:1, 1:1, 1:3, and 0:1) and investigated in the HDS of 4,6-dimethyldibenzothiophene at 300 and 340 oC. The uniformity of the NiFe series was demonstrated by x-ray diffraction analysis and by Fourier transform infrared (FTIR) spectroscopy of adsorbed CO. The position of substitution of Fe was determined by extended X-ray absorption fine structure (EXAFS) analysis. It was found that at 300 oC the HDS activity of the catalysts decreased with increasing Fe content and that this could be explained by the substitution of Fe at the more active Ni(2) sites. As temperature was raised to 340 oC, the activity of the Fe-containing samples increased, although not to the level of Ni2P, and this could be understood from a reconstruction of the NiFe phase to expose more Ni(2) sites. This was likely driven by the formation of surface Ni-S bonds, which could be observed by EXAFS in spent samples.
Ph. D.

Style APA, Harvard, Vancouver, ISO itp.

31

Li, Ke 1969. "A general equilibrium analysis of the division of labour : violation and enforcement of property rights, impersonal networking decisions and bundling sale". Monash University, School of Asian Languages and Studies, 2001. http://arrow.monash.edu.au/hdl/1959.1/9256.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

32

Yoo, Ji Yeon. "Development and application of an in vitro physicochemical upper gastrointestinal system (IPUGS) simulating the human digestive processes". Monash University. Faculty of Engineering. Department of Chemical Engineering, 2009. http://arrow.monash.edu.au/hdl/1959.1/75065.

Pełny tekst źródła

Streszczenie:

Increased and combined knowledge of food processing, molecular biology, health and nutrition has triggered production of many different types of functional foods and pharmaceutics recently. The efficacy and safety of such products are being assessed prior to marketing by in vivo and/or in vitro studies. Traditional in vivo studies require excessive time, cost and labour, as well as ethical approvals with subject to humans or animals in some instances. Therefore excessive number of runs may be avoided if reliable in vitro system is available. During the course of this study, an in vitro physicochemical upper gastrointestinal tract system (IPUGS), the first of its kind in literature, has been developed to simulate the relevant conditions of the gastrointestinal tract (GIT) as closely as possible to the human physiology with multi-disciplinary approach, combining biology, physiology, gastroenterology, process technology, chemical engineering and automation. The IPUGS is aimed at having a high predictive capability towards the real digestion processes occurring in the human upper GIT which allows for examining of the bioavailability of nutrients and drugs, drug-nutrient interactions, viability of probiotics and case studies of gastrointestinal disorders. Digestion of rice and baby foods have been studied with the IPUGS by UV-spectrophotometer, HPLC, light microscope and pH meter under the conditions of normal state and common gastric disorders, such as gastroparesis, dumping syndrome, Zollinger-Ellison syndrome and hypochlorhydria. By comparing the data from many physiological and clinical sources in the literature, it would seem that the IPUGS was able to generate more reliable data compared to the existing in vitro digestion (mechanical) models in the literature. In future, computer-controlled and computer-recorded data by possibly designing a new software or equations would be desirable to implicate a better understanding of the digestive processes.

Style APA, Harvard, Vancouver, ISO itp.

33

Szakal, Andrea L. Bevilacqua Philip C. "The hepatitis delta virus (HDV) ribozyme as a model for RNA catalysis and folding". [University Park, Pa.] : Pennsylvania State University, 2008. http://etda.libraries.psu.edu/theses/approved/WorldWideIndex/ETD-2700/index.html.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

34

Shetty, Manish. "Catalytic upgrading of biomass through the hydrodeoxygenation (HDO) of bio-oil derived model compounds". Thesis, Massachusetts Institute of Technology, 2017. http://hdl.handle.net/1721.1/114309.

Pełny tekst źródła

Streszczenie:

Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, 2017.
Cataloged from PDF version of thesis.
Includes bibliographical references.
Lignocellulosic biomass is an attractive renewable source for fuels and chemicals. Of the many conversion alternatives, catalytic fast pyrolysis has emerged as an attractive technology to convert biomass into fuel additives and value-added chemicals. Current pyrolysis oils or bio-oils are incompatible with refinery streams due to their high acid, water, and water content. The key roadblock in its commercial exploitation is development of catalytic platforms for selective deoxygenation along with minimum hydrogen consumption and carbon loss. Current catalytic solutions including zeolites, and conventional hydrotreating catalysts employ high hydrogen pressures, leading to aromatic ring hydrogenation, and hydrogen consumption. This thesis focusses on developing fundamental catalytic understanding on cheaper and earth-abundant reducible transition metal oxide catalysts for selective hydrodeoxygenation (HDO) of bio-oil derived model compounds using reactivity, computation and characterization studies. The first section focuses on developing structure-reactivity relationships on bulk and supported MoO₃ catalysts for the HDO of lignin-derived model compounds. Characterization reveals that MoO₃ undergoes reduction to catalytically inactive MoO₂ at a temperature of 673 K, and stabilization of partially reduced MoO₃ surface through its partial carburization to oxycarbide phase (MoOxCyHz) at temperatures < 623 K. Thereafter, TiO₂ and ZrO₂ supports prevent the reduction of dispersed oligomeric MoOx species to catalytically inactive species, enhancing their stability. In addition, the overall catalyst reactivity inversely correlates to the maximum hydrogen consumption temperature during hydrogen temperature programmed reduction (H₂-TPR). Furthermore, a near-monolayer oligomeric MoOx dispersion on ZrO₂ support was found to be optimum for HDO reactivity. The second section focuses on developing mechanistic insights into the HDO on bulk and supported MoO₃ with the aid of density functional theory (DFT) computations and kinetic studies. DFT computations were carried out on the elementary steps for HDO of acetone-a model compound on pristine [alpha]-MoO₃ (010) surface to reveal dissociative H₂ adsorption on the (010) surface to be the rate-limiting step. Kinetic studies on MoO₃ supported on ZrO₂ reveal the differences in reaction mechanism and the nature of active sites for HDO on MoO₃/ZrO₂ as compared to bulk MoO₃. The third section focuses on generalizing the low-temperature (< 523 K) selective HDO on other reducible base metal oxides, specifically cobalt oxide and demonstrates oxides to have significantly higher reactivity than base metals for HDO. Finally, lanthanum strontium cobaltite (La₀.₈Sr₀.₂CoO₃), a perovskite oxide, was demonstrated as a novel HDO catalyst at < 523 K. Overall, this thesis provides a toolkit for developing structure-reactivity relationships on reducible metal oxides for their use as HDO catalysts.
by Manish Shetty.
Ph. D.

Style APA, Harvard, Vancouver, ISO itp.

35

RAMASWAMY, EASWAR SINGANELLORE. "AN APPROACH TOWARDS HDL MODEL GENERATION FOR THE MULTI-TECHNOLOGY FIELD PROGRAMMABLE GATE ARRAY". University of Cincinnati / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1139339547.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

36

Lee, Huey-Lin 1974. "Modelling private vehicle use in a computable general equilibrium model of Taiwan". Monash University, Centre of Policy Studies, 2002. http://arrow.monash.edu.au/hdl/1959.1/7895.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

37

Burgess, Stephen Keith 1958. "Business-to-consumer interactions on the Internet : a model for small businesses". Monash University, School of Information Management and Systems, 2001. http://arrow.monash.edu.au/hdl/1959.1/8027.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

38

Pirogova, Elena 1968. "Examination of physicochemical properties of amino acids within the resonant recognition model". Monash University, Dept. of Electrical and Computer Systems Engineering, 2001. http://arrow.monash.edu.au/hdl/1959.1/8424.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

39

Choy, Vivian K. Y. 1971. "Estimating the inevitability of fast oscillations in model systems with two timescales". Monash University, Dept. of Mathematics and Statistics, 2001. http://arrow.monash.edu.au/hdl/1959.1/9068.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

40

Bakharevski, Olga 1968. "Mechanisms of joint injury in an animal model of collagen-induced arthritis". Monash University, Dept. of Medicine, 2000. http://arrow.monash.edu.au/hdl/1959.1/9188.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

41

Marshall, Peter John 1960. "Rational versus anchored traders : exchange rate behaviour in macro models". Monash University, Dept. of Economics, 2001. http://arrow.monash.edu.au/hdl/1959.1/9048.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

42

Bose, Gopal Krishna 1955. "Model selection : an optimal approach to constructing a penalty function in small samples". Monash University, Dept. of Econometrics and Business Statistics, 2002. http://arrow.monash.edu.au/hdl/1959.1/8728.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

43

Wang, Hanzi. "Robust statistics for computer vision : model fitting, image segmentation and visual motion analysis". Monash University, Dept. of Electrical and Computer Systems Engineering, 2004. http://arrow.monash.edu.au/hdl/1959.1/5345.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

44

Miles, William Edward. "Towards an improved model for senior-secondary music education: a multi-faceted perspective". Monash University. Faculty of Education, 2006. http://arrow.monash.edu.au/hdl/1959.1/6572.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

45

Edimon, 1965. "The economy-wide effects of reducing rent-seeking activity : tax evasion in a developing country". Monash University, Dept. of Economics, 1998. http://arrow.monash.edu.au/hdl/1959.1/8664.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

46

Chen, Donghui 1970. "Median-unbiased estimation in linear autoregressive time series models". Monash University, Dept. of Econometrics and Business Statistics, 2001. http://arrow.monash.edu.au/hdl/1959.1/9044.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

47

Galagedera, Don U. A. "Investment performance appraisal and asset pricing models". Monash University, Dept. of Econometrics and Business Statistics, 2003. http://arrow.monash.edu.au/hdl/1959.1/5780.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

48

Denison, Thomas Frank. "Diffusion and sustainability of information and communications technologies in community-based non-profit organisations: an exploratory study of Victoria and Tuscany". Monash University. Faculty of Information Technology. Caulfield School of Information Technology, 2009. http://arrow.monash.edu.au/hdl/1959.1/72047.

Pełny tekst źródła

Streszczenie:

Worldwide, governments and representatives of the community sector believe that the adoption of ICT by community-sector organisations is important because it contributes to the achievement of mission, strategic and business objectives, and benefits the communities those organisations serve. However, despite the fact that many organisations have developed innovative ICT applications, most experience problems in taking up ICT (Burt & Taylor 1999, Surman 2001, DCITA 2005b). This thesis explores the conditions for success and barriers to the take-up and effective use of information and communications technology (ICT), specifically websites and online services, by community-based non-profit organisations, using a study of seventeen organisations based in rural and regional Victoria in Australia, and Tuscany in Italy. In particular, it examines the structural barriers and the inter-organisational relationships that act to facilitate the take-up, or otherwise, of technology by community sector non-profit organisations. The study adopts a grounded theory approach, based on a two-stage data analysis: using the LIAISE framework for the take-up of ICT (Schauder et al. 2005), to identify the factors or conditions that contribute to the development of effective, sustainable websites; and social network analysis to explore the extent to which organisational networks enable the achievement of those conditions. The broad aims of this approach are to enable the evaluation of the existing LIAISE framework and to develop it as a more dynamic systems model capable of serving as a guide to policy and action. The study finds that although the LIAISE framework provides a good taxonomy of the factors important to the take-up of ICT by community-based non-profit organisations, it has weaknesses in that it does not explicitly identify user literacy as a factor, nor does it sufficiently emphasise the importance of an organisation’s external relationships, which provide an essential means of accessing required information and resources such as technical skills, and of enhancing core internal skills such as the ability to develop strategic plans. A new model is proposed to address these weaknesses: ALLIANCE (Applications; Literacy; user Literacy; Infrastructure; Access; Networks; Computing support; and Evaluation).

Style APA, Harvard, Vancouver, ISO itp.

49

Abdul, Razak Normy Norfiza. "Robust Modelling of the Glucose-Insulin System for Tight Glycaemic Control of Less Critical Care Patients". Thesis, University of Canterbury. Department of Mechanical Engineering, 2012. http://hdl.handle.net/10092/7039.

Pełny tekst źródła

Streszczenie:

In the intensive care units, hyperglycaemia among the critically ill is associated with poor outcomes. Many studies have been done on managing hyperglycaemia in the critically ill. Patients in the ICU continue to benefit from the outcome of extensive studies including several randomized clinical trials on glycaemic control with intensive insulin therapy. Tight glycaemic control has now emerged as a major research focus in critical care due to its potential to simultaneously reduce both mortality and cost. Although the debate on tight glycaemic control is on going, managing glycaemic level in ICUs is gaining widespread acceptance as the adverse effects are well known. However, in the less acute wards, to date there have only been a single randomized, controlled study to examine the benefit of glycaemic control. Patients in the less acute wards do not receive the same level of care, as glycaemic control is not regarded as important and not a priority. Glycaemic goals in the less acute wards are often judged based on clinical experience rather than adhering to a standard protocol or a treatment guideline. It is important that patients in the less acute wards received the level of care as practised in the ICU. If hyperglycaemia worsens outcome in the ICU, a similar effect is seen within less acute wards. Hence, tight glycaemic control needs to be extended in the less critical setting as well. To support the establishment of a control protocol for patients in less acute wards, a method that has been successful in the critical care and can be adapted to the less acute wards, is the model based or model-derived control protocol. Model-based protocol can deliver a safe and effective patient-specific control, which means the glycaemic control protocol can be devised to each individual patient. Hence, a physiological model that represents the glucose-insulin regulatory system is presented in this thesis. The developed model, Intensive Control Insulin-Nutrition-Glucose (ICING) is based on the best aspects of two previous clinically-validated glucose-insulin models.

Style APA, Harvard, Vancouver, ISO itp.

50

Bartley, Rebecca. "Quantifying the geomorphic recovery of disturbed streams : using migrating sediment slugs as a model". Monash University, Dept. of Civil Engineering, 2001. http://arrow.monash.edu.au/hdl/1959.1/8395.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

Rozprawy doktorskie na temat „HDE MODEL”

Utwórz poprawne odniesienie w stylach APA, MLA, Chicago, Harvard i wielu innych