Rozprawy doktorskie na temat „Haematology”
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Gray, Atherton. "Immunoliposomes in haematology". Thesis, University of Edinburgh, 1992. http://hdl.handle.net/1842/26559.
Pełny tekst źródłaMainwaring, Gary. "Aspects of fish haematology". Thesis, Swansea University, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.627994.
Pełny tekst źródłaSwart, Luhan. "HIV-associated Hodgkin lymphoma at Groote Schuur Hospital, Western Cape, South Africa". Master's thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/27282.
Pełny tekst źródłaAntel, Katherine. "Splenectomy for immune thrombocytopenia : our 11-year experience". Master's thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/14134.
Pełny tekst źródłaVan, Schalkwyk Willem Adendorff. "The diagnostic utility of bone marrow biopsies performed for the investigation of fever and/or cytopenias in HIV-infected adults at Groote Schuur Hospital". Master's thesis, University of Cape Town, 2009. http://hdl.handle.net/11427/2834.
Pełny tekst źródłaMakgoka, Seretloane Japhtaline. "Effects of bFGF (Basic Fibroblast growth factor) on the Haematopoietic Sequelae that follow transplantation". Master's thesis, University of Cape Town, 2000. http://hdl.handle.net/11427/25551.
Pełny tekst źródłaSeth, Yunus S. "Review and re-appraisal of patients treated with splenectomy for immune thrombocytopenic purpura at five years and beyond". Master's thesis, University of Cape Town, 2002. http://hdl.handle.net/11427/2833.
Pełny tekst źródłaThe risk of pneumococcal infection post splenectomy is life long so all patients undergoing splenectomy are given polyvalent (23-valent) unconjugated pneumococcal polysaccharide vaccine, preoperatively. The aim of this study was 1. to measure the success of splenectomy at a tertiary institution at 5 years and beyond. 2. To review the incidence of complications peri-operatively and long term. 3. Review the need for possible re-vaccination (as recommended in American and British guidelines and 4. perform a re-appraisal of patients found to be refractory to treatment.
Goolam, Hoosen Taahira. "Identification and characterisation of micrornas involved in the pathogenesis of HIV–associated non-Hodgkin's lymphoma". Master's thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/24883.
Pełny tekst źródłaWu, Erxi. "Expression and regulation of ADAMs in cells derived from a range of haematological malignancies". Thesis, University of Sheffield, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312292.
Pełny tekst źródłaStrouboulis, Ioannis John. "Regulation of the complete human #beta#-globin gene locus in transgenic mice". Thesis, Open University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239790.
Pełny tekst źródłaBruce, David. "Antithrombin : structural variants and thrombosis". Thesis, Open University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386084.
Pełny tekst źródłaEdgar, Paul Francis. "The structure and function of corticosteroid-binding globulin". Thesis, University of Cambridge, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.263526.
Pełny tekst źródłaRamorola, Beatrice Relebogile. "HIV alters the expression of miRNA hsa-miR-200c-3p in B-cells, leading to enhanced migration of lymphoma cells". Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29178.
Pełny tekst źródłaTremlett, Catherine H. "Molecular epidemiology of VanA resistant enterococci on a haematology ward". Thesis, University of Manchester, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.499916.
Pełny tekst źródłaPaterson, Pamela J. "The diagnosis and treatment of invasive mould infections in haematology patients". Thesis, University of Aberdeen, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.425016.
Pełny tekst źródłaJames, Rebecca. "A study of the neonatal haematology of children with Down syndrome". Thesis, University of York, 2011. http://etheses.whiterose.ac.uk/4063/.
Pełny tekst źródłaPattipeiluhu, Shelly M. "A study of parasitic fauna of the flounder (Platichthys flesus L.) in the Tyne estuary". Thesis, University of Newcastle Upon Tyne, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295512.
Pełny tekst źródłaMahmoud, T. T. "The haemocytes and heart activity of Episyrphus balteatus DeG. (Syrphidae: Diptera) and their response to environmental factors". Thesis, University of Newcastle Upon Tyne, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370147.
Pełny tekst źródłaBoyd, Helen Kathryn. "Erythropoietin and other growth factors in the anaemia of chronic disorders". Thesis, University of Newcastle Upon Tyne, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241268.
Pełny tekst źródłaHassounah, Fadwa. "A study of some haemoglobinopathies using molecular genetic and mass spectrometric analytical techniques". Thesis, University of Salford, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360389.
Pełny tekst źródłaYong, Kwee Lan. "The effects of myeloid growth factors on phagocyte-endothelium interactions". Thesis, University College London (University of London), 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.388120.
Pełny tekst źródłaSlupsky, Joseph R. "Mechanisms of monoclonal antibody-induced platelet activation". Thesis, University of Liverpool, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240868.
Pełny tekst źródłaLwaleed, Bashir Abdulgader. "Urinary procoagulant activity in health and disease method development and clinical application". Thesis, University of Southampton, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.390721.
Pełny tekst źródłaAtherton, Kirsten. "How do haematology patients make sense of clinical information? : a qualitative study". Thesis, University of Liverpool, 2015. http://livrepository.liverpool.ac.uk/2027839/.
Pełny tekst źródłaBooth, Christopher. "Collaboration of Ezh2 and Runx1 inactivating mutations in malignant haematopoiesis". Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:3f3b18b1-5875-42ed-b025-cf0dd457b99f.
Pełny tekst źródłaMallinson, Gary. "Characterisation of the erythrocyte membrane components which carry the antigens of the LW, Duffy and Cromer blood group systems". Thesis, University of the West of England, Bristol, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294721.
Pełny tekst źródłaDyer, Greg Bryan. "Possible effects of HIV infection on overall survival of patients diagnosed with acute myeloid leukaemia". Diss., University of Pretoria, 2019. http://hdl.handle.net/2263/75830.
Pełny tekst źródłaDissertation (MSc (Medical Oncology))--University of Pretoria, 2019.
This thesis/dissertation is under embargo until September 2023.
Medical Oncology
MSc (Medical Oncology)
Restricted
Caruana, Saviour. "Studies on arteriosclerotic pathologies, haematology, immunology and lipids of captive Atlantic bluefin tuna". Thesis, University of Stirling, 2014. http://hdl.handle.net/1893/21159.
Pełny tekst źródłaPeck, Sarah Jane. "Haematology and Serum Biochemistry of Wild Tasmanian Devils with Devil Facial Tumour Disease". Thesis, The University of Sydney, 2015. http://hdl.handle.net/2123/14904.
Pełny tekst źródłaNg, Hon-yi, i 吳漢怡. "Evaluation of the new red cell parameters on Beckman Coulter DxH800 automated haematology analyzer". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/202311.
Pełny tekst źródłapublished_or_final_version
Pathology
Master
Master of Medical Sciences
Stefan, Daniela Cristina. "Developing a framework for an undergraduate haematology curriculum in a Faculty of Health Sciences". Thesis, Stellenbosch : University of Stellenbosch, 2010. http://hdl.handle.net/10019.1/3187.
Pełny tekst źródłaENGLISH ABSTRACT: The Faculty of Health Sciences at Stellenbosch University adopted a new set of guidelines for curriculum design in 1997, emphasising an orientation towards the requirements of the public sector general practice, a holistic approach and exposure to community lifestyle and disease patterns specific to various communities. In order to ensure the anchoring in the realities of the general practice, a family medical practitioner, appointed by the Academy of Family Practice, was included in the curriculum control structure of the faculty. It was further recommended that a family medical practitioner should be included in the curriculum committee of each discipline, where appropriate. The present research, starting from the assumption that the opinion of a single family practitioner is insufficient to determine the adequacy of the curriculum for general medical practice, aimed to conduct a comprehensive needs analysis of all stakeholders in the undergraduate haematology training programme at the Faculty of Health, Stellenbosch University, and to compare the findings with the existing curriculum. To this purpose, the opinions of five adult medicine haematologists, ten paediatric haematologists, four laboratory haematologists, ten interns, fourteen students and twenty general practitioners were surveyed. An open-ended questionnaire on the usefulness of the haematology module for hospital and independent general practice was analysed, using the “coding technique” method. On this basis, a list of subjects was drawn and, using a Delphi method, the participants in the study were asked to rate their importance for practice. The answers to the open-ended questionnaires revealed a few overarching concepts, the most important being the need to structure the material taught in the form of “approaches”, supporting the differential diagnosis, which is the most frequent task of a general practitioner. Among the outcomes identified in the panellists‟ answers, the need to adequately detect and assess the “red flag” signs for haematological cancers was proposed for consideration as an outcome in the next curriculum. The Delphi survey indicated a group of subjects which were rated as most important for practice and another group designated as devoid of utility. The remaining subjects, rated as of moderate importance, could be further classified as diseases usually managed by the general practitioner and pathology which would be referred to a specialist for management. These iv findings were compared with the existing curriculum and the discrepancies were analysed, resulting in a set of proposals towards a framework for a new undergraduate haematology curriculum. For the first time in the literature, as far as can be determined, this research presents outcomes and content for an undergraduate haematology course which were defined and rated for importance by consensus of the curriculum developers, specialists in the field and graduates of the course. The methods tested in this process and some of the trends revealed might be useful for curriculum development in other medical disciplines.
AFRIKAANSE OPSOMMING: Die Fakulteit van Gesondheidswetenskappe by die Universiteit Stellenbosch het in 1997 nuwe riglyne vir kurrikulumontwerp aanvaar. Hierdie riglyne beklemtoon `n bewustheid van die behoeftes van algemene praktyk in die openbare sektor, `n omvattende benadering tot en blootstelling aan die gemeenskapslewenstyl, asook aan siektepatrone eie aan verskillende gemeenskappe. Om te verseker dat die kurrikulum in die werklikhede van algemene praktyk geanker bly, is `n algemene praktisyn, aangestel deur die Akademie van Huisartskunde, ingesluit in die kurrikulum beheerstruktuur van die fakulteit. Dit is verder ook aanbeveel dat, waar van toepassing, `n huisarts in die kurrikulumkomitee van elke dissipline ingesluit moet word. Hierdie navorsing, wat van die veronderstelling gespruit het dat die opinie van `n enkele huisarts onvoldoende is om die toepaslikheid van `n kurrikulum vir algemene praktyk te verseker, het ten doel gestel om `n omvattende analise van behoeftes van alle belanghebbendes in die voorgraadse hematologie-opleidingsprogram by die Fakulteit van Gesondheidswetenskappe, Universiteit van Stellenbosch, te doen en om die bevindings met die bestaande kurrikulum te vergelyk. Die menings van vyf volwasse medisyne hematoloë, tien pediatriese hematoloë, vier laboratorium hematoloë, tien huisdokters, veertien studente en twintig algemene praktisyns is verkry. `n Oop-einde vraelys oor die bruikbaarheid van die hematologie-module vir hospitaal- en onafhanklike algemene praktyk is m.b.v die gekodeerde tegniek ontleed. Op grond hiervan is `n lys onderwerpe gekies en studiedeelnemers is deur van die Delphi-metode gebruik te maak, gevra om die graad van belangrikheid van elkeen aan te dui. Die antwoorde op die oop-einde vraelys het `n paar oorkoepelende konsepte uitgelig. Die belangrikste hiervan was om die materiaal wat gedoseer word te struktureer in die vorm van „benaderings‟, wat die vorming van `n differensiële diagnose ondersteun. Lg. is die algemeenste taak van die algemene praktisyn. Een van die uitkomste wat deur die studiedeelnemers geïdentifiseer is, nl. die vermoë om die `rooi vlag` tekens van hematologiese kankers korrek te bespeur en te assesseer, is voorgestel vir oorweging vir insluiting as `n uitkoms in die volgende kurrikulum.
Walton, Shasheen. "Effects of season and cohort on the haematology of the geometric tortoise Psammobates geometricus". University of the Western Cape, 2012. http://hdl.handle.net/11394/4543.
Pełny tekst źródłaThe geometric tortoise is one of the world‟s rarest terrestrial tortoises and is endemic to the Southwestern Cape, South Africa. There has been cause for conservation concern for Psammobates geometricus, yet as is common for many species, quantitative physiological research has been lacking. Considering the important role of red blood cells in oxygen circulation, and the role of white blood cells in immune resistance, blood profiles have been used across taxa as a reliable indicator of health status and physiological processes. Forming part of a larger chelonian conservation programme in South Africa, I studied the haematological changes in P. geometricus, to better understand their physiological responses to changes in climatic conditions. Sampled peripheral blood from males, females and juveniles of the largest known wild geometric tortoise population over four seasons (spring, summer, autumn and winter) from August 2000 to June 2001. Blood samples were used to make smears and determine red cell count (RCC), packed cell volume (PCV), haemoglobi concentration (Hb), red cell indices and differential white cell counts. Digital imaging analysis was used for the histological evaluation of stained blood smears, including descriptions of red and white blood cell morphologies, as well as erythrocyte developmental stages. In the cooler periods, geometric tortoises showed low Hb and mean cell haemoglobin concentration values. Erythrocytes were larger and rounder in winter and spring, which were likely due to hydration states. In addition, increased numbers of immature erythrocytes in circulation suggested an erythropoietic response in winter and spring. This regenerative response is common in reptiles emerging from periods of limited activity and is associated with increasing primary production following rainfall events. In the following summer and autumn, increased mean cell haemoglobin concentrations suggested elevated metabolic rates influenced by rising temperatures. This would seem pertinent to meet the extra physical demands associated with foraging effort in the season characterised with limited water and food supply, and mating behaviour, which occurs in the summer. Low body conditions across all cohorts provided evidence for nutrition stress, while erythrocyte size, shape and degenerative responses indicated dehydration stress. Physiological responses to seasonal influences are specific to growth or reproductive demands and differed for each cohort. Males experienced increased Hb, PCV, RCC, and erythrocyte sizes in summer and autumn, which relate to the erythropoieticstimulating effects of androgens. Female erythropoietic cycles in spring accommodate the increased metabolic demands of increased foraging needed for a larger body size and egg production, and again in autumn again for vitellogenesis. Juvenile tortoises showed minimal differences, and could indicate species-specific responses to environmental changes. A spring-related erythropoiesis was observed in juveniles while during summer and autumn, juveniles showed less evidence for dehydration stress than in adults. No haemoparasites were observed in peripheral blood. Seven leukocyte types were identified and included heterophils, eosinophils, basophils, lymphocytes, plasma cells, monocytes and azurophils, in addition to thrombocytes. Heterophils were the most abundant leukocyte, followed by lymphocytes and eosinophils while monocytes and basophils were equally low; plasma cells and azurophils were rare. Heterophil counts were higher in spring than in summer and autumn, and in summer, were more abundant in females than in juveniles. Eosinophil counts were low in spring for all cohorts, and additionally, female and juvenile counts were low in summer. Eosinophils in juveniles were significantly lower than in adults in winter and spring. Lymphocyte numbers increased in autumn for all cohorts, while summer counts were higher in juveniles than in adults. Basophils and monocytes showed minimal seasonal changes, although basophil counts in females in winter tended to be high. Thrombocytes were lowest in spring for all cohorts. Understanding the physiological responses associated with seasonal changes and for each cohort is critical for effective chelonian conservation management. Results obtained from this study indicate a clinically healthy population of Psammobates geometricus and represented the first of this kind to establish baseline haematological reference data for this Critically Endangered tortoise species.
Donoghue, Alan M. "Acute heat illness in underground miners : the clinical state, haematology, biochemistry and risk factors". Thesis, Curtin University, 2000. http://hdl.handle.net/20.500.11937/2196.
Pełny tekst źródłaDonoghue, Alan M. "Acute heat illness in underground miners : the clinical state, haematology, biochemistry and risk factors". Curtin University of Technology, School of Public Health, 2000. http://espace.library.curtin.edu.au:80/R/?func=dbin-jump-full&object_id=11757.
Pełny tekst źródła21%), creatinine (P<0.001, 30%), glucose (P<0.001, 15%), serum osmolality (P=0.030, 71%), creatine kinase (P=0.002, 45%), aspartate transaminase (P<0.001, 14%), lactate dehydrogenase (P<0.001, 9.5%), and ferritin (P<0.001, 26%). The following were depressed on acute presentation compared to recovery (P value, % of acute cases below the normal clinical range): eosinophils (P=0.003, 3 8%) and bicarbonate (P=0.0 11, 32%). Urea and creatinine were significantly raised in miners with heat cramps compared to miners without this symptom (P<0.001), while there was no significant difference in sodium concentration (P=0.384).Mean psychrometric wet bulb temperature was 29.0 degrees celsius (SD 2.2, Range 21.0-34.0). Mean dry bulb temperature was 37.4 degrees celsius (SD 2.4, Range 31.0-43.0). Mean air velocity was 0.54 m/s (SD 0.57, Range 0.00-4.00). Mean air cooling power was 148 W/m(subscript)2 (SD 49, Range 33-290). Mean psychrometric wet bulb globe temperature was 31.5 degrees celsius (SD 2.0, Range 25.2-35.3). Few cases (<5%) occurred at a psychrometric wet bulb temperature <25.0'C, dry bulb temperature <33.8'C, air velocity >1.56 m/s, air cooling power >248 W/m(subscript)2, or psychrometric wet bulb globe temperature <28.5 degrees Celsius.The three surface temperature variables were significantly higher on those days on which heat exhaustion occurred compared to those days on which it did not occur (P<0.001). The relative risk of heat exhaustion on days when the surface 24-hour mean wet bulb globe temperature was in the range 26.0-28.0 degrees celsius was 4.82 (95% CI 2.12-10.96).65 cases of heat exhaustion and 119 controls were studied in the case-control study. Heat exhaustion cases had a significantly higher BMI than controls (P=0.006). The odds ratios increased with BMI. For a BMI of 32.00-36.99, compared to a BMI of less than 27.00 the odds ratio was 3.63 (95% ++
confidence interval 1.42-9.36). V0(subscript)2max was not significantly lower in cases than controls. The odds ratios for heat exhaustion increased with decreasing VO(subscript)2max, but not significantly. The sample size provided 80% power of detecting an odds ratio of 2.5 or greater.Conclusion - Heat exhaustion in underground miners is associated with hypohydration, neutrophil leukocytosis, eosinopenia, metabolic acidosis, increased glucose and ferritin, and a mild rise in CK, AST and LD. Heat cramps are associated with hypohydration but not hyponatraemia. The incidence of heat exhaustion increases during summer and at depth. An increased fluid intake is required. Heat exhaustion would be unlikely to occur if ventilation and refrigeration achieved air cooling power >250W/m2 at all underground work sites. Surface temperature data could be used at this mine to warn miners about the risk of heat exhaustion. Deep underground miners should be advised to maintain a BMI of 24-27.
Fegan, C. D. "The gut mucosal barrier following bone marrow transplantation". Thesis, University of Newcastle Upon Tyne, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308776.
Pełny tekst źródłaAlSaeed, Abbas Habeeb. "The application of flow cytometeric and fluorescent microscopic techniques to the study of multiple myeloma". Thesis, University of Sheffield, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296727.
Pełny tekst źródłaPrinsloo, T. "The evaluation of a new haematological cell counter, the CELL-DYN 3500, on canine leukocyte differential counts". Diss., University of Pretoria, 2001. http://hdl.handle.net/2263/23383.
Pełny tekst źródłaDissertation (M Med Vet (Clinical Laboratory Diagnostics))--University of Pretoria, 2001.
Companion Animal Clinical Studies
unrestricted
Facchini, Raffaella Maria. "Investigating the specific roles of the growth factor kit ligand in the regulation of murine haematopoiesis". Thesis, University of Oxford, 2015. http://ora.ox.ac.uk/objects/uuid:35da4965-5da9-4007-bf97-8408f0f5ed06.
Pełny tekst źródłaMaybury, Helena. "The characterisation of global haemostatic function during pregnancy and the puerperium using thromboelastography". Thesis, University of Leicester, 2007. http://hdl.handle.net/2381/10236.
Pełny tekst źródłaChowdhury, Onima. "Characterisation and targeting of stem cells in myelodysplastic syndromes". Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:741c2079-c6b3-46dc-b4d2-5708693e6cb3.
Pełny tekst źródłaMussai, Francis Jay. "Immunotherapy and immunomodulation for haematological malignancies". Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:6120e659-0dab-4447-b4d6-75e235d3b2c8.
Pełny tekst źródłaYeghen, Tullie. "Diagnosis and epidemiology of Aspergillus fumigatus and Aspergillus flavus infections by molecular techniques in haematology patients". Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.395541.
Pełny tekst źródłaWolmarans, Wilhelm J. "The effect of transport on live weight loss, meat quality and blood haematology in slaughter ostriches". Thesis, Stellenbosch : University of Stellenbosch, 2011. http://hdl.handle.net/10019.1/6762.
Pełny tekst źródłaENGLISH ABSTRACT: The production and export of ostrich meat from southern Africa, to especially the European Union, are increasing rapidly due to the healthy nature of ostrich meat. The European Union has very high standards when importing food products, and it is inevitable that more emphasis is being placed on the production of high quality ostrich meat. Another aspect also of concern to consumers, is the welfare of animals prior to slaughter, and this forces producers to look at ways to decrease stress of animals during the ante-mortem period. Research regarding the effect of stress during the ante-mortem period, and as a result, on meat quality, haematology and weight loss in ostriches, is lacking and thus the purpose of this study was to investigate the effect of various transport distances, travel conditions and different birds on these factors. Ante-mortem stress was measured using serum corticosterone levels (ng/ml), heterophil: lymphocyte (H:L) ratio, white blood cell (WBC) count, aspartate aminotransferase (AST) and creatine kinase (CK), as well as the rate and extent of pH decline in the M. gastrocnemius. Special emphasis was also placed on the meat quality parameters drip loss, cooking loss, colour and Warner-Bratzler shear force (kg/1.27 cm diameter). Live weight losses, as well as carcass weight and weight of bruises cut off from each bird were also recorded during various stages of the trials. The effect of transport distance on the meat quality of ostriches was investigated. Ultimate pHu measurements were taken at 24 hours post-mortem. The muscles of the ostriches from the control group (i.e. birds that were not transported prior to slaughter) had a lower mean pHu (5.77 ± 0.053) than birds that travelled 60 (5.93 ± 0.053) and 600 km (6.11 ± 0.053), respectively. Differences in meat drip loss percentage were also observed between the three treatments. The birds in the control group (0.40 ± 0.07 %) had the lowest meat drip loss percentage compared to the birds that travelled 60 km (treatment C) (1.36 ± 0.07 %) and 600 km (treatment B) (0.97 ± 0.07 %), respectively, to a commcerical ostrich abattoir. Ostriches that were transported for 600 km (8.13 ± 1.16 %) had a greater percentage live weight loss during the antemortem period than birds that travelled a distance of 60 km (2.4 ± 2.185 %) to the abattoir, although both groups were deprived of feed for the same period. When the haematology of the groups that travelled different distances was compared at various time intervals in the ante-mortem period, both groups of birds experienced significant increases in WBC, s-AST and s-CK. An increased H:L ratio from pre-transport to post-transport was only evident in the birds that travelled 600 km (treatment B). However, the birds that travelled 60 km were the only group of birds that had significant elevated serum corticosterone levels during the ante-mortem period. The increase in the various blood parameters indicates severe physical stress, which negatively affected meat quality. Another trial also investigated the effect of various farming systems and transport on meat quality and bruising of ostrich carcasses. Ostriches were raised in three different farming systems, i.e. feedlot -, semiintensive - and free range conditions. Other factors that could maybe impact on stress susceptibility, such as road conditions, floorspace and floor type were also investigated. A significant difference in meat pHu was found between ostriches that were raised in a feedlot (5.95 ± 0.018) and semi-intensive (6.04 ± 0.033) environment. The feedlot birds also had the greatest percentage of carcass weight removed due to bruising. The free range birds were the birds that had the lowest floor density per birds and also had the least amount of bruising on their carcasses. Incidently the other two groups (feedlot and semi intensive) were the birds that travelled on the same type of road (mountain pass) in a truck with rubber flooring whilst the free range birds travelled on a straight road in trucks with metal grid floors.The results indicate that the type of farming system didn’t have a significant influence on meat quality of ostriches, but that factors such as road conditions, flooring and bird density did play a significant role in the incidence of bruises and injuries obtained during transport.
AFRIKAANSE OPSOMMING: Die produksie en uitvoer van volstruisvleis vanuit suidelike Afrika, na veral die Europese Unie, is gedurig aan die toeneem as gevolg van die gesonde aard van volstruisvleis. Die Europese Unie het baie hoë standaarde wanneer dit kom by die invoer van voedselprodukte en dit is onvermydelik dat meer klem op die produksie van hoë gehalte volstruisvleis gelê word. ʼn Ander aspek wat ook kommer wek by verbruikers is die welstand van diere voor slagting en hierdie aspek noodsaak produsente om te kyk na maniere om stres te beperk tydens die periode voor slagting. Navorsing rakende die effek van stres tydens die ante-mortem periode, asook vleiskwaliteit, hematologie en gewigsverlies in volstruise as gevolg van vervoer, ontbreek. Die doel van die studie was dus om die invloed van verskillende vervoerafstande, vervoersomstandighede en tipe produksiesisteme op volstruise se stresrespons te ondersoek. Die omvang van ante-mortem stres is bepaal deur die serum-kortikosteroon vlakke (ng/ml), heterofiel: limfosiet (H:L) ratio, witbloedsel (WBS) telling, aspartaat aminotransferase AST en creatien kinase CK, asook die tempo en vlak van pH-daling in die M. gastrocnemius, te meet. Spesiale klem is gelê op die vleisgehalte parameters kookverlies, drupverlies, kleur en Warner-Bratzler-skeurwaardes (kg/1.27 cm deursnee). Gewigsverlies is aangeteken op verskillende stadiums tydens die proewe. Karkasgewigte en die hoeveelheid gewig afgesny van elke volstruiskarkas a.g.v. kneusings is ook bepaal. Die eerste studie het die invloed van vervoerafstand op vleiskwaliteit van slagvolstruise ondersoek. Vleis kwaliteit parameters soos pH, drip verlies, kook verlies, taaiheid en kleur is ondersoek. Die pHu metings is op 24 uur post-mortem geneem. Slagvolstruise in die kontrole groep (d.i. -volstruise wat nie voor slagting vervoer is nie) het ’n laer vleis pHu (5.77 ± 0.05) gehad as voëls wat onderskeidelik 60 km (5.93 ± 0.05) en 600 km (6.11 ± 0.05) ver vervoer is. Verskille in persentasie dripverlies is gesien tussen die vleis van die voëls wat nie vervoer is nie (0.40 ± 0.07 %) en die voëls wat 60 km (1.36 ± 0.07 %) en 600 km ver (0.97 ± 0.07 %) onderskeidelik vervoer is. Volstruise wat vir 600 km (8.13 ± 1.16 %) vervoer is, het ‘n groter persentasie lewende gewig tydens die ante-mortem periode as voëls wat 60 km (2.4 ± 2.19 %) ver vervoer is na die abattoir, verloor, al was beide groepe weerhou van voer vir dieselfde tydperk. Beide groepe wat vervoer is (60 en 600 km) het merkbare toenames in witbloedsel (WBS) tellings, s-AST’s en s-CK’s getoon tydens die ante-mortem periode. Daar is slegs ʼn toename in H:L ratio (ʼn indikator van stres) van voor vervoer tot na vervoer gesien in die voëls wat 600 km vervoer is. Daarteenoor was die voëls wat slegs 60 km vervoer is die enigste voëls wat ʼn toename in korticosteroon vlakke getoon het gedurende die ante-mortem periode. Die toenames is heel moontlik ‘n aanduiding van erge fisiese stres wat ‘n negatiewe effek op vleiskwaliteit het. Die tweede studie het die effek van verskillende produksiesisteme en die stress respons van die verskillende groepe slagvolstuise op vervoer ondersoek. Vleis kwaliteit parameters soos pH, drip verlies, kook verlies en taaiheid is ondersoek. Die hoeveelheid kneusings per volstruis is ook gemeet. Daar was ‘n beduidende verskil (P = 0.009) tussen die pHu van die voerkraal (5.95 ± 0.018) en semi- intensiewe (6.04 ± 0.033) volstruise. Die voerkraal volstruise se vleis het die grootste drip- en kookverliese gehad in vergelyking met die ander twee groepe (semi-intensiewe en ekstensiewe) terwyl die ekstensiewe volstruise die taaiste vleis gehad het. Die voerkraalvoëls het ook die grootste persentasie karkasgewig verloor a.g.v. kneusings wat afgesny is. Die ekstensiewe voëls het die laagste vloer digtheid per volstruis gehad asook die minste kneusings. Die ander twee groepe (voerkraal en semi intensief) was die groepe wat op dieselfde pad vervoer is (bergpas) in vragmotors wat rubber vloere gehad het terwyl die ekstensiewe voêls op ‘n reguit pad vervoer is in ‘n vragmotor met ‘n metaal oppervlakte. Die resultate van die studie is ‘n aanduiding dat die tipe plaassisteem nie ‘n groot impak op die hoeveelheid akute stres ervaar deur die voëls tydens vervoer gehad het of gevolglik op die vleiskwaliteit van die volstruise nie, maar dat faktore soos pad toestand, tipe vloer en voëldigtheid wel ‘n wesenlike rol speel in die voorkoms van kneusings en beserings opgedoen tydens vervoer.
no, nicolai@bonne, i Nicolai Johnsen Bonne. "Psittacine beak and feather disease : vaccination, haematological response and pcr methodology". Murdoch University, 2010. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20100211.182512.
Pełny tekst źródłaSparks, Sharna. "Blood cell histology of Homopus areolatus: effects of season and cohort". University of the Western Cape, 2015. http://hdl.handle.net/11394/4776.
Pełny tekst źródłaHomopus areolatus is an endemic terrestrial tortoise that resides in a Mediterranean type of climate, which is characterised by winter rainfall and mild winter temperatures. Within ectotherms, such as H. areolatus, physiological changes are elicited by changes in the ambient temperature. These physiological changes are evident in the blood profile of reptiles. I described the morphology of immature and mature erythrocytes, leukocytes as well as thrombocytes of H. areolatus. Additionally, I evaluated erythrocytes, leukocytes and thrombocytes to assess the effects of season and cohort on these cells. Blood samples were collected in 2000 and 2001 at Elandsberg Nature Reserve in the Western Cape from H. areolatus cohorts (female, male, juvenile) in all seasons (spring, summer, autumn, winter). Blood smears were made and stained with modified Giemsa stain. SigmaStat was used for all statistical analysis. Immature erythrocyte types within H. areolatus included basophilic rubricytes, polychromatophilic rubricytes and polychromatophilic erythrocytes. Upon my evaluation, I encountered evidence to suggest that small and large immature erythrocytes possibly developed from two distinctive lineages. Further research is required to discern which lineage gave rise to which immature erythrocyte type. Cohort had no effect upon immature erythrocytes. Erythropoiesis was most prevalent during winter and spring within H. areolatus. Aberrant features of erythrocytes appeared to be more prevalent during autumn, which signified the driest season with limited food and water. Mature erythrocytes play a huge role in oxygen transport and metabolism in individuals. Factors such as size and shape are relevant since small, mature, ellipsoidal erythrocytes transport oxygen more efficiently than large, spherical erythrocytes. In H. areolatus small, mature, ellipsoidal erythrocytes appeared to be most prevalent during spring and summer. During winter however, large, spherical erythrocytes appeared to be most prevalent. Thrombocytes and seven types of leukocytes were observed within H. areolatus, namely heterophils, lymphocytes, eosinophils, basophils, monocytes, plasma cells and azurophils. Among cohort and season heterophils were most prevalent overall, followed by lymphocytes and eosinophils respectively. Basophils, monocytes, plasma cells and azurophils were present but overall, were relatively few. H. areolatus appeared to be healthy, and leukocyte counts as well as its dimensions appeared to be in accordance with other reptilian studies. This study serves as the first baseline haematological reference forH. areolatus. The study forms the second of its kind on South African tortoises, only one other haematological study has been done namely, P. geometricus which is a sympatric species to H. areolatus.
Brandimarti, Maquel E. "Using haematology and biochemistry to investigate the health and evolutionary biology of eastern grey kangaroos (Macropus giganteus)". Thesis, The University of Sydney, 2021. https://hdl.handle.net/2123/26627.
Pełny tekst źródłaMoller, Cheryl. "The haematology of bobtail lizards (Tiliqua rugosa) in Western Australia: reference intervals, blood cell morphology, cytochemistry and ultrastructure". Thesis, Moller, Cheryl (2014) The haematology of bobtail lizards (Tiliqua rugosa) in Western Australia: reference intervals, blood cell morphology, cytochemistry and ultrastructure. Masters by Research thesis, Murdoch University, 2014. https://researchrepository.murdoch.edu.au/id/eprint/22862/.
Pełny tekst źródłaPhilpott, Nicola Jane. "Apoptosis and the pathogenesis of aplastic anaemia". Thesis, University of Oxford, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359983.
Pełny tekst źródłaWong, Kah-Keng. "Validation of lymphoma-associated antigens identified using autoantibody profiling and protein arrays". Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:51ac6bbe-2845-43cc-9b7a-cb92097155f1.
Pełny tekst źródłaLutteropp, Michael. "The emergence and early fate decisions of stem and progenitor cells in the haematopoietic system". Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:eef3e876-bde2-4114-8ac2-bf0c87492a55.
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