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1

Sail, Paul D. "Lifetime measurements of the Bs->KK system and RICH studies at LHCb". Thesis, University of Glasgow, 2013. http://theses.gla.ac.uk/4859/.

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Lifetime analyses in heavy flavour systems can provide excellent opportunities to make precision measurements of Standard Model (SM) parameters that probe for new physics. This thesis presents lifetime measurements from the Bd and Bs mesons to the charmless two-body hadron family of decays, known as B->hh, where h can be either a kaon or a pion. A particular interest is given to the Bs->KK decay channel. The Bs->KK channel is interesting as it decays into a CP even final state, with a small amount of CP violation predicted by the Standard Model. This can be quantified using the decay rate asymmetry parameter A Delta Gamma. The decay is also loop dominated, and thus sensitive to New Physics (NP) that could enter in these processes. These effects can be studied by constraining the values of the decay rate difference, Delta Gamma s, and A Delta Gamma from a lifetime measurement of the Bs->KK. A method used to measure the effective lifetime of the B->hh channels, which removes the acceptance bias induced by the event selection, is described. This includes fits to the invariant mass and reconstructed lifetime spectrums, together with the methods employed to determine the per-event acceptance functions from data and treatment of non-parametric backgrounds. The application of this method to two datasets is then presented. Both datasets are collected using a centre of mass energy sqrt{7 Tev} with the first dataset from the 2010 run comprising a total integrated luminosity of 37 inverse pb, and the second from the 2011 run comprising a total integrated luminosity of 1.0 inverse fb. The fit methods are verified using various techniques, primarily using a simplified MC simulation and full LHCb Monte Carlo (MC). The fit to the mass spectrum of the Bd->Kpi from the 2011 dataset is used both for the lifetime measurement, and for the normalisation in a search for the Bds->ppbar decay. As the details of the lifetime analysis methods are subtly different between datasets, the sources of uncertainty differ between the analyses. The lifetime measurement resulting from the 2010 dataset is found to be tau_{Bs->KK} = 1.440 +/- 0.096 ps stat +/- 0.008 ps syst. The resulting B->hh lifetimes, measured from the 2011 dataset are found to be tau_{Bs->KK} = 1.407 +/- 0.016 ps stat +/- 0.007 ps syst, tau_{Bd->Kpi} = 1.524 +/- 0.011 ps stat +/- 0.004 ps syst, tau_{Bs->piK} = 1.597 +/- 0.056 ps stat +/- 0.012 ps syst. These measurements are consistent with previous measurements, with the value of tau_{Bs->KK} measured from the 2011 dataset having a greater precision than the current world average. From this, we are able to directly measure the quantity A Delta Gamma for the first time, with the value evaluated found to be A Delta Gamma = -0.87 +/- 0.17 stat +/- 0.13 syst. Particle IDentification (PID) of the family of B->hh decays is crucial for distinguishing the many different final states that are kinematically similar. These final states tend to overlap in mass when reconstructed, providing considerable difficulties when making measurements with them. The Ring Imaging CHerenkov (RICH) detectors provide the experiment with PID capability, which allow high precision measurements from these channels to be made. During data taking periods, it is important to monitor the performance of the many subsystems that allow the RICH operations to run smoothly. Two studies are presented in this thesis that pertain specifically to RICH 2. The first studies the stability of the spherical and flat mirrors, using the Laser Alignment Monitoring System (LAMS). A direct correlation between observed movement and temperature is found, which is in the order 10-70 micro rad/K and agrees with estimates based on the expansion coefficients of materials and the mirror supports. This is an order of magnitude lower than the angular resolution of RICH 2, so does not affect the resolution or performance of the detector. The second study suggests an alternative method to constrain the refractive index of the RICH gas. This method allows for continuous monitoring of the refractive index, with a greater frequency in time than is currently available. The method is purely data driven and is found to be in agreement with the currently employed RICH method to within 1%.
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2

Hatteland, Karl. "Evolution of Control System(s) for a Multi Joint Snake : Transformer <-> #13". Thesis, Norwegian University of Science and Technology, Department of Computer and Information Science, 2007. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-8741.

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This thesis is about evolving a control system for a snake called Transformer <-> #13. This is a mechanical snake with several body parts. The choise was to use a cellular genetic algorithm where each body part is a cell. These contain “DNA”, one ruleset for each degree of freedom in the joints, which decides how it will behave in relation to its neighbour body parts. Three different fitness functions have been implemented which each gives a distinct and different behaviour. The goal of the different fitness functions is; crawling far, rising high and making geometry. The crawling part was successfull, while the other two goals was much harder for the snake and didnt provide great results. Concluding that the snake is appropriate for crawling around and making an impression of different cubic forms. Which for artist purposes is adequate, but it fails on getting into specific shapes.

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3

Mourikis, Fotios. "Thermodynamic analysis of an SOFC-GT system for marine application on a LNG carrier". Thesis, University of Strathclyde, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502289.

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The aim of this research is to perform a thermodynamic analysis of an SOFe - gas turbine (GT) hybrid power plant, including economical aspect, so as to examine its appropriateness (through the study of several cases) for marine application on an LNG carrier. Provided the data concerning properties and costs of materials, the developed model is to fit for a wide range of parametric analysis of thermodynamic cycles. This prospect takes into the consideration that SOFe is a promising technology with lots of advantages in comparison to conventional marine combustion engines; it is much more efficient, friendlier to the environment, more fuel flexible and operates under high operating temperatures which enable a successful thermal integration with bottoming cycles (gas turbine cycles) in order to achieve a higher efficiency. In general terms, an LNG carrier has a high energy demand. Through this analysis, it is shown in certain extent the SOFe - GT system can be developed either for the main propulsion of the vessel or the APU (Auxiliary Power Unit). The latter is a more practical possible solution as it is of less exigent energy. The program used for this analysis is divided into two sections; the pre-reforming section and the electrochemical (SOFC) section together with the gas turbine including the cost model as well. Another issue which is examined in this thesis is the fluctuation of charter rates of a specific LNG carrier depending on the size of the investment. The height of the investment is defined by the power output of the SOFe installation. The final results give a theoretical and general idea of the way that this hybrid power plant could be exploited by an LNG carrier implying whether it can be preferred to the conventional combustion engines or not.
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4

Marques, do Nascimento Vanuza. "Détecteurs de rayonnement (IR->THz) innovants à base d'oxydes fonctionnels". Thesis, Normandie, 2019. http://www.theses.fr/2019NORMC244.

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Ce travail évalue le potentiel des couches minces LSMO déposées sur substrat silicium comme détecteur de rayonnement à température ambiante, en exploitant la variation de sa résistance électrique. La fabrication de structures suspendues et les caractérisations électro-thermiques (R(T), conductance thermique, temps de réponse), optiques et les performances en bruit sont présentés. Des mesures optiques avec différentes sources de rayonnement (635 nm, 3,39 µm, corps noir, et faisceau synchrotron) ont été réalisées. Les performances obtenues sont très intéressantes car les puissances équivalentes de bruit (NEP) peuvent atteindre quelques pW·Hz-1/2 à 300 K. Les caractérisations optiques réalisées montrent que ces détecteurs sont au niveau de l'état de l'art. Le bolomètre est sensible dans ces différentes gammes alors que celui-ci n'était pas couplé à une antenne. Un modéle électro-thermique et des simulations éléments finis sont présentés, ils permettent de comprendre le comportement des bolomètres en fonction du point de fonctionnement choisi (courant de polarisation, température). Les constantes de temps thermique (de l’ordre de 1 ms) et les consommations électriques (quelques dizaines de μW) sont faibles. Ces performances sont très prometteuses comparativement à l’état de l’art des détecteurs non refroidis. Les applications envisagées sont celles nécessitant un faible nombre de détecteurs performants, dans la gamme infrarouge jusqu’au THz
This work evaluates the potential of LSMO thin films deposited on a silicon substrate as a radiation detector at room temperature, by exploiting the variation of its electrical resistance. The fabrication of suspended structures and electro-thermal (R(T), thermal conductance, response time) and optical characterizations are presented as well as and noise performance. Optical measurements with different radiation sources (635 nm, 3.39 μm, black body, and synchrotron beam) were performed. The obtained performances are very interesting because the noise equivalent power (NEP) can reach pW·Hz-1/2 to 300 K. The optical characterizations realized show that these detectors are at the state-of-the-art level. The bolometer is sensitive in these different ranges while it was not coupled to an antenna. An electro-thermal model and finite element simulations are presented, they make possible the understanding of the behaviour of the bolometers as a function of the chosen operating point (polarization current, temperature). The thermal time constants (around 1 ms) and the electrical consumptions (a few tens of μW) are low. These performances are very promising compared to the state-of-the-art of uncooled detectors. The applications envisaged are those requiring a small number of sensitive detectors, in the infrared range up to THz
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5

Ali, Haider. "An approach to create a virtual network for co-design process>". Thesis, Högskolan i Borås, Institutionen Handels- och IT-högskolan, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-20607.

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With the increasing popularity of information technologies, many companies try to set up a virtual network in order to share their business information. The purpose of creating such a virtual network is to create a new knowledge base on the combination of the existing knowledge. Collaboration is very necessary in such a virtual network as crass-unit collaboration takes place when people from different units work together in cross-unit teams on a common task or provide significant help to each other. Recently, co-design is an emerging technology in the field of informatics. It is considered as the development of system thinking, and it is a collaborative designing process which recruits designers, researchers, stakeholders and others together. The purpose of this collaborative activity is to sole designing problems. Therefore, if we want to increase collaboration in a co-design process, we need to look at a ways of increasing the efficiency of collaboration. The rapid development of accessible, reliable, and user-friendly information technology offers improvements to traditional collaboration, and makes new approaches possible. Many platforms for the exchange of information such as the Internet, email, and video-conferencing are well established aids to collaborative activities. Therefore, my research investigates to create an efficient virtual network for a co-design process. In this research, I will try to investigate that what is the need of a virtual network for co-design process and what are those virtual network soft-wares which can help us in a co-design process. My research discussion is related to the theory of CSCW (Computer Supported cooperative work).
Program: Magisterutbildning i informatik
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6

Last, Iain Jeffrey. "A measurement of #GAMMA#(Z'0 -> B'* X)/#GAMMA#(Z'0 -> hadronic) using the DELPHI detector at LEP and development of a testbeam data acquisition system". Thesis, University of Liverpool, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309882.

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7

Putzmann, Ninja [Verfasser]. "<> sportpolitische System Spaniens : eine theoretisch-empirische Analyse von Akteuren, Outputs und Entwicklungslinien / Ninja Putzmann". Köln : Zentralbibliothek der Deutschen Sporthochschule, 2017. http://d-nb.info/1193197147/34.

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8

Melachrinos, Constantinos. "The Muon Detection System and W Z --> 3l̳(e̳, [mu]) cross section measurement at CMS". Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/44757.

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Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Physics, 2008.
In title on title page, "[mu]" appears as lower case Greek letter; and, double underscored "l" and "e" appear as script.
Includes bibliographical references (p. 57-59).
The startup of the Large Hadron Collider will allow scientists to probe energy scales that existed picoseconds after the Big Bang. Monte Carlo samples of many Standard Model processes are produced to simulate the conditions in the Compact Muon Solenoid detector. Data analysis techniques are developed to measure the cross section of the W Z --> 3l(e, [mu]) decay channel. The results are [sgima]all = 723.4 ± 27.6(stat.) ± 144.7(syst.) fb for integrated luminosity 1 fb-1. Cross section measurements deduced by our data analysis techniques agree with the theoretical predictions, [sigma] pred. all = 708 ± 26.6 fb. The selection of W Z --> 3l events gave 43.5 ± 6.6 signal events with 6.4 ± 2.5 background events, enough to claim an observation at the level of five standard deviations. The understanding of this process will aid in the search for the Higgs boson, as well as in the search for new physics in the early stages of the operation of the detector.
by Constantinos Melachrinos.
S.B.
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9

Kälvelid, Fredrik. "Numerical Modeling of Plain Journal Bearings within a Heavy-Duty Engine Oil System using GT-SUITE". Thesis, Umeå universitet, Institutionen för fysik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-114674.

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Main and connecting rod bearings along the crankshaft in a heavy-duty engine oil system requires efficient feed of oil flow to ensure the performance of lubrication, cooling and cleaning. The bearings and builded bearing models considered in this work are based on a Volvo 13L engine. Two main models to predict the oil flow in main and connecting rod bearings have been investigated using the system analysis software GT-SUITE. These two models are based on two numerical methods called  the Mobility method and the Reynold's equation respectively. The main bearing and the connecting rod large end bearing loads calculated in the present work is similar to the reference bearing loads, especially for connecting rod large end bearing and at lower engine speeds. For higher engine speeds, the present load results are far off,  compared to the reference load results. This difference at the higher engine speeds showed also an increased difference in the oil volume flow rates. But more information regarding the calculations of the reference loads is needed to analyze the differences further. Considering the "split lines", where the upper and the lower bearing shell meet, in the bearing models increased the oil volume flow rate with 13.3\% on average for the main bearing. Main bearing stand for 86\% of the total flow whilst connecting rod large end and small end bearing stand for the rest 13\% and 1\% of the total flow. The feed of oil to main bearing and connecting rod large end bearing appears continuously whilst the feed of oil to connecting rod small end bearing appears in the form of a few pulsations. Comparing to the numerical reference flow results, the results in this work are similar at high oil temperatures and at low engine speeds, otherwise the results are far off. Considering the Reynold's equation when predicting the oil volume flow rates in plain journal bearings is a more accurate way than using the Mobility method since it takes more specific geometrical irregularities into account. The oil volume flow rate for main bearing differ with 2.7\% on average when solving the Reynold's equation compared to the Mobility method.
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10

Wester, Jorge Victor Wilfredo Cachay. "Caracterização molecular do módulo regulador TT (Traqueia-Tórax) de >Drosophila melanogaster". Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/17/17136/tde-06062017-163006/.

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Estudos funcionais anteriores identificaram um módulo cis-regulador (MCR) de 67 pb (-253/- 187) na região promotora do gene de pufe de DNA BhC4-1 que dirige a expressão do gene repórter na glândula anelar de Drosophila melanogaster. Uma análise bioinformática identificou 67 sequências de D. melanogaster que são similares a sequências contidas no MCR de glândula anelar. Uma das sequências identificadas reside em um fragmento genômico de 657 pb localizado aproximadamente 2500 pb à montante do CG13711, 400 pb à montante do CG12493, em uma região genômica que constitui um dos íntrons do CG32239 (Gef64C). A caracterização preliminar de três linhagens transformadas com a construção 657 pb-lacZ mostrou expressão do gene repórter no sistema traqueal de larvas e prépupas e no tórax de adultos. Baseado padrão de expressão promovido por este MCR, o mesmo foi denominado Traqueia-Tórax (TT). O principal objetivo do presente trabalho constituiu estender a caracterização molecular das linhagens da série TT-lacZ. Inicialmente embriões, larvas de primeiro, segundo e terceiro estádio, prépupas 0 h, 1 h e 2 h, pupas 24 h e adultos com 1, 3 e 5 dias foram investigados quanto ao padrão de expressão do repórter utilizando ensaio histoquímico que detecta atividade de ?-galactosidase. A expressão do gene repórter é inicialmente detectada no sistema traqueal durante o terceiro estádio larval e continua a ser detectada neste tecido em prépupas 0 h, 1 h e 2 h e pupas 24 h. Em adultos, a expressão do gene repórter é verificada nos músculos longitudinais dorsais em adultos de 3 e 5 dias. Uma vez que o MCR TT reside em uma região intergênica e a informação disponível sobre os CGs próximos ainda é escassa, não foi possível inferir qual dos CGs é regulado pelo MCR TT. Neste contexto, o padrão de expressão do RNAm do gene repórter lacZ e do CG13711, CG12493 e CG32239 foi investigado no sistema traqueal de larvas e prépupas e no tórax de adultos de uma das linhagens da série TT-lacZ utilizando RT-qPCR. Os níveis de expressão do RNAm lacZ aumentam cerca de 3 vezes em prépupas 0 horas, quando comparados com os níveis de expressão do RNAm lacZ presentes no sistema traqueal de larvas de terceiro estádio. Um padrão de expressão similar foi observado no caso do CG32239 e do CG13711. Nos tóraxes de adultos de 3 e 5 dias de idade os níveis de expressão do RNAm lacZ aumentam cerca de 37 vezes e 11 vezes, respectivamente, quando comparados aos níveis de expressão iv do RNAm lacZ presentes nos tóraxes de adultos de 1 dia. No tórax de adultos, o único CG que apresenta um padrão de expressão similar ao padrão de expressão de lacZ constitui o CG12493. Em conjunto, nós concluímos que o MCR TT promove um padrão dinâmico de expressão durante o desenvolvimento. Além disso, com base nos resultados de RT-qPCR, nós sugerimos que o MCR TT regula a expressão do RNAm do CG32239 no sistema traqueal durante a transição larva-prépupa e também a expressão do RNAm do CG12493 no tórax de adultos de 3 e 5 dias de idade. Além de estender a caracterização funcional de um novo MCR, nossos resultados também contribuem com novas informações acerca dos padrões de expressão no desenvolvimento de três CGs de D. melanogaster.
Previous functional studies identified in the DNA puff BhC4-1 promoter region a 67 bp (- 253/-187) cis-regulatory module (CRM) that drives reporter gene expression in the ring gland of D. melanogaster. A bioinformatics analysis identified 67 Drosophila melanogaster sequences that are similar to sequences contained in the ring gland CRM. One of the identified sequences resides in a 657 bp genomic fragment located about 2500 bp upstream CG13711, about 400 bp upstream CG12493, in a genomic region that constitutes one of the introns of CG32239 (Gef64C). The preliminary characterization of three transgenic lines transformed with a 657 bp-lacZ construct revealed reporter gene expression in the larval/prepupal tracheal system and in adult thorax. Based on the pattern of expression driven by this CRM we named it Trachea-Thorax (TT). The main goal of this work was to extend the molecular characterization of the lines of the TT-lacZ series. Initially ?-galactosidase histochemical assays were performed in embryos, first, second and third instar larvae, 0h, 1h and 2h prepupae, 24 h pupae and 1, 3 and 5 days old adults. Reporter gene expression is initially detected during the third larval instar in the tracheal system and continues to be detected in this tissue at 0 h, 1h and 2 h prepupa and, 24 h pupa. During the adult stage, reporter gene expression is verified in the dorsal longitudinal muscles of 3 and 5 days old adults. Since the TT CRM lies in an intergenic region and the available information about the nearby CGs is still scarce it was not possible to infer which of the CGs is regulated by the TT CRM. In this context, the mRNA pattern of expression of the lacZ reporter gene and of CG13711, CG12493 and CG32239 was investigated in the tracheal system of both larvae and prepupae and in adult thoraxes of one of the transgenic lines of the TT-lacZ series using RTqPCR. The lacZ mRNA expression levels increase about 3 times in 0 h prepupae when compared to the lacZ mRNA expression levels present in the tracheal system of third instar larvae. A similar pattern of expression was observed for both CG32239 and CG13711. In three and five days old adult thoraxes lacZ mRNA expression levels increase about 37 times and 11 times, respectively, when compared to lacZ mRNA expression levels present in one day old thoraxes. In the adult thorax, the only CG that presents a similar pattern of expression constitutes CG12493. Overall, we conclude that the TT CRM drives a dynamic pattern of ii expression throughout development. Additionally, based on RT-qPCR results, we suggest that the TT CRM regulates the expression of CG32239 mRNA in the tracheal system during the larvae to prepupae transition, as well as the expression of CG12493 mRNA in the thorax of 3 and 5 days old adults. Besides extending the functional characterization of a novel CRM our results also contribute new information about the developmental patterns of expression of three Drosophila melanogaster CGs.
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11

Chakravarthula, Venkata Adithya. "Transient Analysis of a Solid Oxide Fuel Cell/ Gas Turbine Hybrid System for Distributed Electric Propulsion". Wright State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=wright1484651177170392.

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12

Wadner, Martin. "Co-Simulation of Engine Model and Control System with focus on Turbocharger Model". Thesis, Luleå tekniska universitet, Institutionen för teknikvetenskap och matematik, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-81059.

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The demands on heavy duty vehicles is constantly raising with government legislations on CO2 emissions becoming stricter and increasing customer demands. A continuous search for new methods and tools is a crucial element in finding more performance and lower emissions, which are prerequisites for heavy duty vehicles of the future. This thesis is conducted at Scania CV AB and aims at proposing a co-simulation setup which implements the engine management system, EMS, for turbocharger control, into engine simulation models that the company uses to simulate the behaviour of their combustion engines. The EMS software for turbocharger control is modelled in a MATLAB Simulink model and the engine simulation model is modelled in GT-SUITE. The thesis is also suggesting improvements to a turbine model that is modelled within the given EMS software. The results suggest a co-simulation setup that enables the engine simulation models to utilize the EMS software for turbocharger control which thereby enhances their ability to predict engine behaviour. The setup can also be used as a tool during the development process for other part of the EMS and could ease the need for physical engine tests in test cell. The suggested improvements to the turbine model revolves around building a model capturing the aspects of a so called twin scroll turbine and also to implement a better estimation of the turbine efficiency. The improvements to the turbine model ultimately leads to improving the response behaviour of the EMS turbocharger control system.
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13

Eriksson, Mikael, i Daniel Olovsson. "An Alternative Variable Valve Timing System for Heavy Duty Vehicles". Thesis, Luleå tekniska universitet, Institutionen för teknikvetenskap och matematik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-60153.

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The ability to control engine valve timing has the potential to alter the engine performance over the entire operating range. The outcome of valve timing technology enables the possibility to increase efficiency, lowering emissions, increase engine torque, etc. One of the simplest ways to obtain a variable valve timing is to use cam phasers. The dynamics of a hydraulic cam phaser has been studied, three concepts with the purpose to control such an element has been developed using simulation driven product development. Focus have been on robustness, simplicity and implementation. A final concept using on/off solenoids to control a torque driven cam phaser has been designed and simulated in GT-SUITE which validated its performance and functionality. A dynamic model was built in Simulink which simulated the behaviour of the cam phaser and provided tools for optimizing the rotor design. By combining the knowledge of mechanical- and control engineering at Scania, the development process of such machine elements was effective. The outcome of this thesis has given a new perspective in understanding these components and their potentials.
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Hawn, David Phillip. "Development of a Dynamic Model of a Counterflow Compact Heat Exchanger for Simulation of the GT-MHR Recuperator using MATLAB and Simulink". The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1236091152.

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Srikanth, Sai Aswin. "Use of Electrical Coolant Pumps in Scania’s Cooling System". Thesis, KTH, Maskinkonstruktion (Avd.), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-259681.

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The automotive industry is currently traversing through the electrification wave. Numerous manufacturers are directing focus to electrify their lineup and reduce emissions. In the frontier of heavy duty diesel trucks, electrification of auxiliary units remains an unexplored potential. An optimized cooling system functioning in sync with a controllable electric coolant pump attempts to reduce parasitic losses and emissions. The cooling flow requirements in challenging conditions may also be fulfilled. Although electric coolant pumps are found increasingly in passenger cars, the implication of independently operating them in a heavy duty diesel truck is an important objective to be explored. The purpose of this project is to generate different cooling system layouts coupled with electrical coolant pumps. The performance of these layouts is compared with the volume flows in a standard cooling system. Refined layouts which fulfill the cooling system requirements are chosen for verification. 1-D Simulation is used to correlate and verify the trends of the test rig data. The results show an adequate gain in the total volume flow across distinct layouts with the electric coolant pumps. However, numerous challenges are required to be overcome.
Bilindustrin befinner sig mitt i en våg av elektrifiering. Flertalet tillverkare fokuserar på att elektrifiera sitt produktutbud och att minska utsläppen. Inom forskningen kring tunga transporter med dieseldrivna lastbilar, är elektrifiering av kylsystemet ett outforskat område. Ett optimerat kylsystem som är reglerbart med en elektrisk kylvätskepump skulle potentiellt kunna minska energiförluster och utsläpp. Kravet på flödet av kylvätska vid utmanande driftsfall skulle också kunna bli bättre uppfyllda än för dagens system. Trots att det blir allt vanligare att personbilar har elektriska kylvätskepumpar, så har det inte utforskats vad det innebär att ha reglerbara elektriska kylvätskepumpar i dieseldriva lastbilar. Därför är detta ett viktigt område att utforska. Målet med detta projekt är att skapa olika kylsystemskoncept, där den elektriska kylvätskepumpen är en systemkomponent. Prestandan hos dessa principlösningar jämförs sedan med volymflödet i ett standard kylvätskesystem. Koncept som uppfyller kraven för kylvätskesystemet kommer att bli utvalda för vidare verifiering. 1-D simuleringar används för att hitta samband och verifiera mot trenderna som hittas i resultat från en testrigg. Resultaten visar en förbättring i det totala volymflödet för flera av lösningarna, som har en elektrisk kylvätskepump. Men det finns fortfarande flera utmaningar som behöver övervinnas.
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Galdun, John P. "A MECHANISTIC STUDY OF AN iPSC MODEL FOR LEIGH’S DISEASE CAUSED BY MtDNA MUTATAION (8993 T>G)". VCU Scholars Compass, 2016. http://scholarscompass.vcu.edu/etd/4411.

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Mitochondrial diseases encompass a broad range of devastating disorders that typically affect tissues with high-energy requirements. These disorders have been difficult to diagnose and research because of the complexity of mitochondrial genetics, and the large variability seen among patient populations. We have devised and carried out a mechanistic study to generate a cell based model for Leigh’s disease caused by mitochondrial DNA mutation 8993 T>G. Leigh’s disease is a multi-organ system disorder that depends heavily on the mutation burden seen within various tissues. Using new reprogramming and sequencing technologies, we were able to show that Leigh’s disease patient fibroblasts reprogrammed to induced pluripotent stem cells maintain the same level of mutation burden seen in the original patient cell line. Mutation burden was maintained through several passages and spontaneous differentiation. This cell based model could be useful for future pathogenesis studies, or therapeutic drug screenings in a patient and tissue specific manner.
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17

Hainque, Elodie. "Transition de poursuite oculaire chez l'homme : vers une compréhension de la constitution d'un modèle interne d'un <&gt". Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066332.

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Afin de poursuivre une cible en mouvement, le système nerveux central (SNC) utilise deux types de mouvements oculaires: la poursuite et les saccades. Les saccades sont des mouvements rapides et brefs de redirection de l’axe visuel d’un centre d’intérêt à un autre. La poursuite est un mouvement lent qui tend à maintenir la cible d’intérêt sur la fovéa. La vitesse de l’œil étant toujours inférieure à celle de la cible, une erreur positionnelle entre l’œil et la cible va croître en l’absence de mouvement correctif. Des saccades de rattrapage sont déclenchées par le SNC pour corriger cette erreur. Alors qu’il est largement reconnu que le système de la poursuite utilise un modèle interne du mouvement de la cible pour améliorer ses capacités, la modalité de contrôle de l’amplitude des saccades de rattrapage est sujette à controverse quant au rôle direct d’afférences sensorielles ou d’un modèle interne de la cible en mouvement. Nous avons développé un nouveau paradigme de transition de poursuite oculaire appliqué à l’Homme sain, dans lequel la cible change de manière imprévisible d’un profil de vitesse non constant périodique à un profil de vitesse non constant apériodique. Nos résultats confirment que le SNC utilise un modèle interne de la cible en mouvement pour contrôler l’amplitude des saccades de rattrapage. Ce modèle se construit progressivement à partir de 168 millisecondes après le changement de profil de vitesse et est utilisé conjointement par les systèmes de la poursuite et saccadique. Le substrat neuronal potentiel de ce modèle interne sera discuté à la lumière des connaissances issues de la littérature concernant le contrôle moteur et oculomoteur
Two types of eye movements are combined while tracking a moving object: smooth pursuit and saccades. Saccades are rapid redirections of the visual axis between two centers of interest. Because pursuit gain is smaller than one, the eye would increasingly lag behind the target without any correcting movements. Thus, “catch-up saccades” are triggered by the central nervous system (CNS) to cancel this growing position error between the eye and the target. It is widely accepted that an internal model of target motion is used by the CNS to cancel inherent delays between visual input and smooth pursuit motor output, ensuring accurate tracking of moving targets. The amplitude of catch-up saccades triggered during smooth pursuit could be corrected by a delayed sensory signal to account for the ongoing target displacement during catch-up saccades. Yet, recent studies suggested that the correction of catch-up saccade amplitude must also be done through an internal model of target motion. We developed a new paradigm in which the target switches unexpectedly from one target with a non-constant periodic velocity profile to another with a non-constant aperiodic velocity profile. Our results in healthy humans confirm that the CNS uses an internal model of target motion to correct catch-up saccade amplitude. Internal model is being built gradually from 168 ms after the target switch. We show that a common internal model of target motion is shared within the CNS to control smooth pursuit and to correct catch-up saccade amplitude. The potential neuronal substrate of such an internal model will be discussed in the light of the knowledge from the literature on motor and oculomotor control
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18

Thurnherr, Tina. "Studies on vertebrate nervous system myelination : <> role of Cdc42, Rac1, and profilin 1 signaling in oligodendrocyte and Schwann cell biology /". Zürich : ETH, 2006. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=16771.

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19

Oliveira, Carlos Eduardo de Jesus Guimarães. "PCAISO-GT: uma metaheurística co-evolutiva paralela de otimização aplicada ao problema de alocação de berços". Universidade do Vale do Rio dos Sinos, 2013. http://www.repositorio.jesuita.org.br/handle/UNISINOS/3185.

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Este trabalho apresenta um algoritmo de otimização baseado na metaheurística dos Sistemas Imunológicos Artificiais, princípios de Teoria dos Jogos, Co-evolução e Paralelização. Busca-se a combinação adequada dos conceitos de Teoria dos Jogos, Co-evolução e Paralelização aplicados ao algoritmo AISO (Artificial Immune System Optimization) para resolução do Problema de Alocação de Berços (PAB). Dessa maneira, o algoritmo é formalizado a partir das técnicas citadas, formando o PCAISO-GT: Parallel Coevolutionary Artificial Immune System Optimization with Game Theory. Inicialmente, foram realizados experimentos visando à sintonia dos parâmetros empregados nas diferentes versões da ferramenta desenvolvida. Com base nas melhores configurações identificadas, foram realizados experimentos de avaliação através da solução de um conjunto de instâncias do PAB. Os resultados obtidos permitiram a indicação da versão co-evolutiva associada à teoria dos jogos como a melhor para solução do problema em estudo.
This paper presents an optimization algorithm based on metaheuristic of Artificial Immune Systems, principles of Game Theory, Co-evolution and parallelization. The objective is find the appropriate combination of the concepts of Game Theory, Co-evolution and Parallelization applied to AISO algorithm (Artificial Immune System Optimization) for solving the Berth Allocation Problem (BAP). Thus, the algorithm is formalized from the above mentioned techniques, forming the PCAISO-GT: Parallel Coevolutionary Artificial Immune System Optimization with Game Theory. Initially, experiments aiming to tune the parameters were performed using different versions of the tool developed. Based on the identified best settings, evaluation experiments were carried out by solving a set of instances of the PAB. The results obtained allowed the appointment of co-evolutionary version associated with game theory as the best solution to the problem under study.
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20

Sun, Xiangfei. "Modeling the Biota Population Impact on Polychlorinated Biphenyls Transport and Simulating PCBs Anaerobic Biodegradation in the Lake System". Research Showcase @ CMU, 2018. http://repository.cmu.edu/dissertations/1148.

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21

Demmel, Lars. "Unraveling Phosphatidylinositol 4-kinase function in the yeast Golgi-endosomal system". Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2005. http://nbn-resolving.de/urn:nbn:de:swb:14-1126694538661-76719.

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In Saccharomyces cerevisiae, experiments with temperature-sensitive mutants of the PI4-kinase Pik1p revealed that the PI4P pool generated by this enzyme is essential for Golgi morphology and normal secretory function and that the PI4P pool at the Golgi represents a regulatory signal on its own. In order to function as a spatial and temporal regulator of membrane traffic, PI4P synthesis and turnover must be tightly regulated. It remains elusive which factors are involved in the targeting and regulation of Pik1p. Little is also known about PI4P binding proteins mediating the effects of this phosphoinositide on Golgi function. Since it has been shown that multiple pathways leave the Golgi towards the plasma membrane one can ask the question whether Pik1p and its product PI4P specifically control one pathway? Here we demonstrate an interaction of Pik1p with the 14-3-3 proteins Bmh1p and Bmh2p. Interestingly, overexpression of Bmh1p and Bmh2p results in multiple genetic interactions with genes involved in late steps of exocytosis and it affects the forward transport of the general amino acid permease Gap1p. The detected interaction depends on the phosphorylation state of Pik1p and Pik1p phosphorylation accompanies its shuttling out of the nucleus into the cytoplasm where presumably the binding to Bmh1/2p occurs. Therefore, we reason that these interactions might serve the sequestration of Pik1p away from the Golgi. This study reveals that Pik1p shows a strong effect on the delivery of Gap1p to the surface whereas the transport of exocytosis markers implicated in the direct Golgi-to-plasma membrane pathway are not significantly disturbed. Cells carrying a deletion of gga2 also show a strong defect in delivery of Gap1p to the surface. In addition, pik1-101 gga2[delta]double mutants display synthetic genetic and membrane transport phenotypes and recruitment of Gga2 to the TGN partially depends on functional Pik1p. Therefore, our results suggest a role of Pik1p in the TGN to endosome pathway.
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22

Gravert, Maike. "Novel regulators of trafficking in the yeast Golgi-endosomal system". Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2006. http://nbn-resolving.de/urn:nbn:de:swb:14-1160402018221-35061.

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Over the past few years a large amount of work has provided growing insight into the molecular mechanisms that direct post-Golgi trafficking events in the budding yeast Saccharomyces cerevisae. However, a key event in this process, the formation of secretory vesicles at the Golgi and sorting of cargo into these transport carriers, remains poorly understood. It has been demonstrated that phosphatidylinositol 4-phosphate (PI(4)P) generated by the PI(4)-kinase Pik1p plays an essential role in maintenance of Golgi secretory function and morphology. Up to now relatively few targets of Pik1/PI(4)P signaling at the Golgi have been identified and it thus remains elusive how Pik1p mediates its essential function in Golgi secretion. During my thesis work, I used synthetic genetic array analysis (SGA) of a temperature-sensitive mutant allele of PIK1 (pik1-101) in order to gain better understanding of Pik1p function at the TGN and to isolate new regulators of post-Golgi transport in yeast. I identified a total of 85 genes, whose deletion resulted in a synthetic growth defect when combined with the pik1-101 mutation. 21 isolated deletion mutants were used for further analysis, several of which were found to share common trafficking phenotypes with the pik mutant. A striking result of the screen was the finding that Pik1p interacts genetically with several components of a potential post-translational modification pathway referred to as “urmylation pathway”. In addition, a novel, previously uncharacterized subunit of the Transport protein particle (TRAPP) complex was isolated as genetic interactor of Pik1p, suggesting a function for the TRAPP complex in a Pik1p dependent trafficking pathway. Using tandem affinity purification, I could also demonstrate that TRAPP shows previously unknown interactions with other regulators of post-Golgi transport. The second part of this thesis describes the development of a new visual screening approach. Recent work indicates that secretory cargo in yeast can be transported to the cell surface via at least two different exocytic branches. Upon block of one pathway cargo can be partially redistributed into the other pathway. This partial redundancy of exocytic pathways provides one explanation why genetic screens in the past were largely unsuccessful in identifying the molecular machinery that directs vesicle budding and cargo sorting at the TGN. I collaborated in the development of a novel screening method that was devised to circumvent this problem. The method took advantage of the systematic yeast knockout array and was based on the assumption that a defect in cargo sorting and cell surface transport could be detected as intracellular accumulation of a GFP-tagged model cargo. The suitability of our approach for identifying regulators of secretory transport has been demonstrated in a small-scale pilot study that will be presented in this thesis. The screening method proofed to be applicable on a genome-wide scale and can now be used for the screening of additional markers. This novel approach provides an entry point to the comprehensive study of TGN sorting.
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23

Piucci, Alessio [Verfasser], i Stephanie [Akademischer Betreuer] Hansmann-Menzemer. "Amplitude analysis of Lambda_b^0 --> Lambda_c^+ D^0 K^- decays and pentaquark searches in the Lambda_c^+ D^0 system at the LHCb experiment / Alessio Piucci ; Betreuer: Stephanie Hansmann-Menzemer". Heidelberg : Universitätsbibliothek Heidelberg, 2019. http://d-nb.info/1199348864/34.

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24

Allebone, Lisa Rowan. "A CP simulation study of the decay mode Bo/d -> D*⁻π⁺ at LHCb and the development of the pixel hybrid photon detectors for the RICH system". Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.423260.

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Neves, Fabricia Junqueira das. "Função autonômica e reatividade vascular em indivíduos com parentesco de diabetes tipo 2 e em portadores do polimorfismo 894G>T da óxido nítrico sintase endotelial". Universidade do Estado do Rio de Janeiro, 2009. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=1441.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
As doenças cardiovasculares estão entre as principais causas de mortalidade em muitos países. O sistema nervoso autônomo e a função endotelial constituem mecanismos centrais no desenvolvimento e progressão de doenças cardiovasculares. A função autonômica e a reatividade vascular podem estar alteradas em indivíduos com maior risco para doença cardiovascular, como indivíduos com história familiar de primeiro grau de diabetes tipo 2 (HFDM2) e indivíduos com polimorfismo 894G>T da enzima óxido nítrico sintase endotelial (eNOS). Os objetivos dos três artigos apresentados na tese foram: artigo I. Investigar a influência da HFDM2 na modulação autonômica cardíaca em ausência de desordens metabólicas concomitantes; artigo II. Investigar a influência da HFDM2 na reatividade vascular em ausência de desordens metabólicas concomitantes e, artigo III. Investigar a influência do polimorfismo 894G>T no efeito de uma sessão de exercício dinâmico máximo na reatividade vascular. Foram recrutados indivíduos saudáveis com e sem HFDM2 para os artigos I e II. A variabilidade da frequência cardíaca (VFC) foi determinada através da análise espectral de um registro de intervalos RR durante 10 minutos na posição supina (artigo I) e a reatividade vascular durante a hiperemia reativa através da pletismografia de oclusão venosa (artigo II). Para a realização do artigo III, foram recrutados indivíduos saudáveis com e sem o polimorfismo 894G>T da eNOS. O protocolo consistiu na determinação da reatividade vascular basal e durante a hiperemia reativa, o qual eram realizados pré, 10, 60 e 120 minutos após um teste de esforço cardiopulmonar máximo. Os indivíduos com HFDM2 apresentaram maiores valores para variáveis antropométricas e metabólicas e uma menor VFC (artigo I) e reatividade vascular (artigo II) quando comparados com o grupo-controle (p<0,05). Em seguida, os grupos foram emparelhados para essas variáveis consideradas capazes de alterar a VFC e a reatividade vascular e nenhuma diferença significativa foi encontrada entre os grupos nos artigos I e II (p>0,05). Foi realizada análise de correlação simples, sendo que as variáveis que apresentaram significância estatística foram submetidas à análise de regressão múltipla. Esta identificou colesterol (P=0,014) e triglicerídeos (P=0,014) como preditores independentes da VFC (modelo r2=0,16; P<0,001) e insulina (P<0,05) e razão cintura-quadril (P<0,05) como preditores independentes da reatividade vascular (modelo r2=0,22; P=0,006). No artigo III, não foram observadas diferenças entre os indivíduos com e sem o polimorfismo 894G>T em relação as características antropométricas, metabólicas e hemodinâmicas e medidas de fluxo sanguíneo antes do exercício dinâmico máximo (P>0,05). Os indivíduos polimórficos apresentaram menor reatividade vascular independente do tempo (efeito do grupo P=0,019) e a análise de post-hoc revelou que os indivíduos polimórficos apresentavam valor menor apenas no momento 120 minutos (P=0,022) quando comparados com indivíduos sem o polimorfismo. Estes achados sugerem que indivíduos com HFDM2, em ausência de desordens metabólicas concomitantes, não apresentam alteração da modulação autonômica cardíaca e de reatividade vascular. Em adendo, indivíduos com polimorfismo 894G>T, têm menor reatividade vascular após um sessão de exercício, denotando a presença de disfunção vascular.
Cardiovascular diseases are among the leading causes of mortality in many countries. The autonomic nervous system and the endothelial function are central mechanisms in the development and progression of cardiovascular diseases. The autonomic function and vascular reactivity may be altered in subjects with higher risk for cardiovascular disease, as subjects with family history of first-degree relatives of type 2 diabetes (FDRs), and subjects with the 894G>T polymorphism of the endothelial nitric oxide synthase (eNOS). The aims of these three papers presented at this thesis were: paper I. To investigate the influence of FDR on cardiac autonomic modulation in the absence of concomitant metabolic disorders; paper II. To investigate the influence of FDR on vascular reactivity in the absence of concomitant metabolic disorders; paper III. To investigate the influence of the 894G>T polymorphism on the effect of a single bout of maximal dynamic exercise on vascular reactivity. Healthy subjects with and without FDRs were recruited for the paper I and II. The heart rate variability (HRV) was determined by spectral analysis of inter-beat intervals recorded during 10 min in the supine position (paper I) and vascular reactivity during the reactive hyperemia by venous occlusion plethysmography (paper II). For the paper III, healthy subjects with and without the 894G>T polymorphism of the eNOS were recruited. The protocol consisted of vascular reactivity assessment at baseline and during reactive hyperemia, which were performed pre, 10, 60 and 120 min after a maximal cardiopulmonary exercise test. The FDRs exhibited higher values for anthropometric and metabolic variables and lower values for HRV (paper I), and vascular reactivity (paper II) when compared to the control subjects (p<0.05). After matching the groups for variables, that are known to alter HRV and vascular reactivity, no significant difference was observed between groups in the paper I and II (p>0.05). Following single correlation analysis, only the variables with statistical significance were submitted to multiple regression analysis. This identified cholesterol (P=0.014) and triglycerides (P=0.014) as significant predictors of HRV (model r2=0.16; p<0.001), and insulin (P<0.05) and waist-to-hip ratio (P<0.05) as independent predictors (model r2=0.22; P=0.006). There were no differences between the subjects with and without the 894G>T polymorphism concerning anthropometric, metabolic, and hemodynamic characteristics, and blood flow measurements before maximal dynamic exercise (P>0.05), in the paper III. The polymorphic subjects presented lower vascular reactivity regardless of time (P=0.019 for group main effect), and post-hoc analysis revealed that polymorphic subjects had lower values only at the 120 min measurement (P=0.022) when compared with subjects without the polymorphism. These findings suggest that FDRs, in the absence of concomitant metabolic disorders, does not impair cardiac autonomic modulation and vascular reactivity. Furthermore, subjects with the 894G>T polymorphism had lower vascular reactivity after a single bout of exercise, denoting the presence of vascular dysfunction.
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26

Bernardinello, Martina. "Optimization of a high performance engine GDI Wet System and its control via virtual analysis and experimental tests". Master's thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amslaurea.unibo.it/24587/.

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This thesis describes a combined 1-D numerical and experimental analysis of a GDI injection system. The aim is to design the GDI injection system to have the minimum injection variability between injectors. This is possible analysing the rail pressure waves that affect the injections. Thanks to a MATLAB numerical code the results coming from a first calibration attempt were compared with experimental data to verify the reliability of the acquired results. They were calculated after specific tests made on the hydraulic test bench developed at Lamborghini. Different configurations were studied changing the system geometry, such as rail diameter, high pressure pipe length and inlet position inside the rail, flow-restrictor diameter at the end of high pressure pipe. Eight different configurations were analysed and the one that showed the lowest CoV of injection was proposed as a final design. Then a 1-D numerical analysis of the GDI injection system was developed on the chosen configuration with the aim of predicting pressure waves propagation phenomena and the injected mass flow rate. The focus of the 1-D analysis is to verify through the comparison between simulated values and experimental ones if the model predicts accurately the physics of the system, in order to use it on a wider range of operating points. The following step consisted in controlling the GDI pump in MIL environment through a cosimulation between high pressure system model built in GT-ISE and control model made with Simulink. The high pressure control model was developed and validated. The aim was to have a closed loop control of the rail pressure using the same ECU control strategy. The main task of the control is to actuate the angle, respect to pump TDC, the MSV valve had to be closed to make the actual pressure follow the target one. The control model and the simulation in MIL environment are very useful since they help on the precalibration of ECU functions, reducing testing activities.
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27

Reshöft, Klaus. "Zeitaufgelöste STM-Untersuchungen zur Silizid- und Metall-Epitaxie der Systeme Fe-, Cu-, Pt-Si(111) und Cu-W(110)". [S.l. : s.n.], 2001. http://e-diss.uni-kiel.de/diss>=/d525.pdf.

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28

Dalke, Phillip Allen. "Model-Based Design and Analysis of Thermal Systems for the Ohio State EcoCARMobility Challenge Vehicle". The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu159545443238678.

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29

Meyer, Karsten. "Flussgleichungen für das Anderson-Gitter zur Beschreibung von Schwer-Fermion-Systemen". Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2004. http://nbn-resolving.de/urn:nbn:de:swb:14-1079709122000-46905.

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In der vorliegenden Arbeit wird die Physik von Schwer-Fermion-Systemen, die durch Lanthanid- und Aktinid-Übergangsmetallverbindungen realisiert werden, untersucht. Die Basis für eine theoretische Beschreibung bildet das Anderson-Gitter, welches das Wechselspiel freier Leitungselektronen und stark korrelierter Elektronen aus lokalisierten f-Orbitalen charakterisiert. Als Zugang zu diesem Modell wird die von Wegner vorgeschlagene Flussgleichungsmethode verwendet, ein analytisches Verfahren, welches auf der Konstruktion eines effektiven Hamilton-Operators basiert. Ein zentrales Thema dieser Arbeit ist die Beschreibung der elektronischen Struktur von Schwer-Fermion-Systemen. Insbesondere wird die Abhängigkeit statischer Größen vom Einfluss verschiedener Systemparameter betrachtet. Die Dynamik kollektiver Anregungen in Schwer-Fermion-Systemen wird an Hand der elektronischen Zustandsdichten und dynamischen magnetischen Suszeptibilitäten untersucht
The physical properties of heavy-fermion systems are examined. These systems are mainly formed by rare earth or actinide compounds. Their essential physics can be characterized by the periodic Anderson model which describes the interplay of itinerant metal electrons and localized, but strongly correlated f-electrons. The present calculations are based on the flow equations approach proposed by Wegner. This method uses a continuous unitary transformation to derive an effective Hamiltonian of an easy to treat structure. Within this framework the electronic structure of heavy-fermion systems is calculated and the influence of external parameters is studied. Beside the derivation of static properties the density of states and dynamic magnetic susceptibilities are investigated in order to characterize the nature of collective excitations
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30

Meyer, Karsten. "Flussgleichungen für das Anderson-Gitter zur Beschreibung von Schwer-Fermion-Systemen". Doctoral thesis, Technische Universität Dresden, 2003. https://tud.qucosa.de/id/qucosa%3A24313.

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In der vorliegenden Arbeit wird die Physik von Schwer-Fermion-Systemen, die durch Lanthanid- und Aktinid-Übergangsmetallverbindungen realisiert werden, untersucht. Die Basis für eine theoretische Beschreibung bildet das Anderson-Gitter, welches das Wechselspiel freier Leitungselektronen und stark korrelierter Elektronen aus lokalisierten f-Orbitalen charakterisiert. Als Zugang zu diesem Modell wird die von Wegner vorgeschlagene Flussgleichungsmethode verwendet, ein analytisches Verfahren, welches auf der Konstruktion eines effektiven Hamilton-Operators basiert. Ein zentrales Thema dieser Arbeit ist die Beschreibung der elektronischen Struktur von Schwer-Fermion-Systemen. Insbesondere wird die Abhängigkeit statischer Größen vom Einfluss verschiedener Systemparameter betrachtet. Die Dynamik kollektiver Anregungen in Schwer-Fermion-Systemen wird an Hand der elektronischen Zustandsdichten und dynamischen magnetischen Suszeptibilitäten untersucht.
The physical properties of heavy-fermion systems are examined. These systems are mainly formed by rare earth or actinide compounds. Their essential physics can be characterized by the periodic Anderson model which describes the interplay of itinerant metal electrons and localized, but strongly correlated f-electrons. The present calculations are based on the flow equations approach proposed by Wegner. This method uses a continuous unitary transformation to derive an effective Hamiltonian of an easy to treat structure. Within this framework the electronic structure of heavy-fermion systems is calculated and the influence of external parameters is studied. Beside the derivation of static properties the density of states and dynamic magnetic susceptibilities are investigated in order to characterize the nature of collective excitations.
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31

Staack, Ingo. "Aircraft Systems Conceptual Design : An object-oriented approach from <element> to <aircraft&gt". Doctoral thesis, Linköpings universitet, Fluida och mekatroniska system, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-132614.

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Aircraft Conceptual Design (ACD) is facing new challenges on the way to enhanced fidelity level required of the nowadays complex system design. Namely the integration of models and simulations of different fidelity levels to enhance the analysis capability while maintaining a streamlined, transparent, and low cost working process is required. In this thesis, the use of object-oriented Knowledge-Based Engineering (KBE) methods to enable an early integration of simulation models within the ACD phase are presented. Careful investigations of modelling and simulation approaches of multi-domain systems are carried out before, and their use in the ACD phase is examined regarding the efficiency between spend effort and result in accuracy. Enabling the named topics, a central, parametric information model approach is presented. By the extended use of XML, XSD and XSLT, domain-specific models can be translated from this dataset, supporting a direct CAD and automated simulations integration. Modelling systems as graph networks is a simple approach for unified modelling within the conceptual design stage. Based on this theory, the similarity of different modelling approaches like Dependency Structure Matrix (DSM), MDDSM, or Channel-Agency Networks is shown. Using object-oriented programming, all these and more aspects such as e.g. Fault Tree Analysis (FTA) can be globally handled as one graph set. Based on the outcomes of the theoretical part, the development of a ACD framework is described. Backed by a central XML-based namespace, this framework integrates a complete CAD environment to ensure an appropriate environment for the geometric domain modelling. Furthermore, the use of KBE for automated simulation model integration is exemplified by a whole aircraft simulation including the hydraulic aircraft flight control system (FCS).
Mit steigenden Anforderungen durch immer mehr optimierte, leistungsfähigere, zuverlässigere und langlebigere technische Produkte nimmt die Modellierung und Simulation einen immer größeren Stellenwert ein. Um das Zusammenspiel von Systemen bereits im Flugzeugvorentwurf analysieren zu können, bedarf es einer geschickten Systemmodellierung und geeigneter Arbeitsprozesse, die die Erstellung von Simulationsmodellen auf Basis unvollständiger Daten- und Informationslage ermöglichen. Vor Allem, um das volle Optimierungspotential moderner, integrierter elektrischer Systemarchitekturen ausschöpfen zu können, ist eine Einbeziehung dieser in das Gesamtkonzept innerhalb des Flugzeugvorentwurfs notwendig. In dieser Arbeit wird ein wissensbasierter Arbeitsprozess (englisch: Knowledge-Based Engineering) für den Flugzeugvorentwurf präsentiert, welcher die Zusammenführung unterschiedlicher Informationen – wie z.B. Domänen- und Produktspezifischer Daten ermöglicht. Dies soll die Einbeziehung der Bordsystemarchitekturen dienen, um die gestiegenen Genauigkeitsanforderungen im Flugzeugvorentwurf bewältigen zu können. Dem vorausgehend werden verschiedene Modellierungsgrundsätze erörtert und ihre Anwendungsmöglichkeit im Hinblick auf die mögliche Implementierung und Anwenderfreundlichkeit im Flugzeugvorentwurf diskutiert. Ausgehend von den theoretischen Überlegungen wird die Entwicklung eines XML-basierten Flugzeugvorentwurfsprogramms beschrieben, das die vollständige Integration eines kommerziellen CAD-Werkzeuges ermöglicht. DesWeiteren werden die Möglichkeiten aufgezeigt, welche sich durch den Einsatz eines universalen Modells im XML-Format ergeben. Durch Interpretation der Produktdaten in Form eines Graphennetzwerks werden verschiedene Modellierungs- und Analysemöglichkeiten wie Beispielsweise DSM und C-A Net Modell erörtert und die Integration von Teilaspekten wie der Systemzuverlässigkeit aufgezeigt. Ziel ist ein universeller Modellierungsansatz, der eine plausible, verständliche und anwenderfreundliche Integration der verschiedenen Teilaspekte des Flugzeugvorentwurfs ermöglicht sowie die Einbindung domäne-spezifischer Programme (wie z.B. CAD) mit Hilfe einer parametrischen, auf XML basierenden Datenbank erlaubt.
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32

Kieser, W. E., K. Leung, N. Krestina, R. P. Beukens, X.-L. Zhao i A. E. Litherland. "Development of an Automated Combustion and Gas-fed Ion Source System for Environmental Monitoring and Biomedical ^<14>C Applications(Proceedings of the 19^ Symposium on Chronological Studies at the Nagoya University Center for Chronological Research in 2006,Part1)". 名古屋大学年代測定資料研究センター, 2007. http://hdl.handle.net/2237/13677.

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第19回名古屋大学年代測定総合研究センターシンポジウム平成18(2006)年度報告<第1部> Proceedings of the 19th symposiumon on Chronological Studies at the Nagoya University Center for Chronological Research in 2006 日時:平成19 (2007)年1月15日(月)~17日(水) 会場:名古屋大学シンポジオン Date:January15th-17th, 2007 Venue:Nagoya Uhiversity Symposion Hall
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Huber, Stefan M. "Synthese, Stereoelektronik und Synthesepotential neuartiger indigoider Systeme n->p*- vs. n->d*-Konkurrenz in Ethen- und Imidazoliumderivaten /". [S.l.] : [s.n.], 2007. http://deposit.ddb.de/cgi-bin/dokserv?idn=983754640.

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Stiller, Christoph. "Design, Operation and Control Modelling of SOFC/GT Hybrid Systems". Doctoral thesis, Norwegian University of Science and Technology, Faculty of Engineering Science and Technology, 2006. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-718.

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This thesis focuses on modelling-based design, operation and control of solid oxide fuel cell (SOFC) and gas turbine (GT) hybrid systems. Fuel cells are a promising approach to high-efficiency power generation, as they directly convert chemical energy to electric work. High-temperature fuel cells such as the SOFC can be integrated in gas turbine processes, which further increases the electrical efficiency to values up to 70%. However, there are a number of obstacles for safe operation of such a system, such as fuel cell damage through thermal loads or undesired chemical reactions, or gas turbine problems related to high thermal capacity and volume of the pressurised components. Development of suitable plant design as well as operation and control strategies is hence a key task for realisation of the mentioned systems.

The first part of the thesis describes the utilised models. All component models that have been developed and applied for the work are mathematically defined based on a fixed pattern. The thermodynamically most relevant components are tubular SOFC, indirect internal reformer and heat exchangers, and spatially discretised models are used for these. For the turbomachinery, map-based steady-state behaviour is modelled. Gas residence times and pressure drops are accounted for in all components they are relevant.

Based on the component models, three different hybrid cycles are examined. In the first cycle, the SOFC replaces the combustion chamber of a recuperated single-shaft turbine. The SOFC is pressurised and the cycle is called “directly integrated SOFC cycle” (DIC). Further cycle options are a DIC with a two-shaft gas turbine (DIC-2T) and an indirectly integrated SOFC cycle (IIC). In the latter, the compressed gas is heated recuperatively with the exhaust gas and the SOFC is operated at ambient pressure by connecting its air inlet to the turbine exhaust. All cycles incorporate the SOFC system design proposed by Siemens-Westinghouse, including indirect internal reforming, a tubular SOFC bundle and anode recirculation by an ejector. The first cycle (DIC) is regarded as standard cycle.

Objectives for highly efficient, safe system design are formulated and design parameters are associated. A design calculation determines the design parameters for the standard cycle, based on a nominal power output of 220 kW. The design LHVbased electric efficiency is app. 63%. Related to the design point, steady-state part-load ability of the system is analysed and displayed in two-dimensional performance maps where each axis represents one degree of freedom. Degrees of freedom considered are fuel and air flow; fuel utilisation is assumed constant. A result is that a strategy with constant mean fuel cell temperature is most advantageous in terms of safe and gentle operation. Further advantages of this strategy are the ability for low part-load and high efficiency at part-load operation.

A control strategy is derived for dynamical implementation of the found part-load strategy. The system power output is primarily controlled by the SOFC power. The fuel utilisation is kept within certain bounds and the fuel flow is manipulated to control it to its design value. The fuel cell temperature is controlled by the air flow, which again is controlled by manipulating the GT shaft speed through the generator power. To determine the required air flow, a mixed feedforward and feedback strategy is used, where the feedforward part calculates a prediction based on the net power output and the feedback part provides correction based on the measurement of the SOFC fuel outlet temperature. Additional constraints to the control system are the supervision of the shaft speed and the valid operation regime of the anode recirculation ejector.

The proposed control strategy provides robust control. The mean SOFC temperature, however, shows large transient deviation upon large load steps. The time to reach the setpoint power for large load steps is up to 70 s, while small load steps are followed in typically 1-2 s. A conclusion is that the system is suitable for load following operation as long as small load steps occur, as for example in distributed power generation for residential applications.

Shutdown and startup strategies are introduced where the gas turbine provides air for cooling/heating throughout the procedures. Additional equipment and piping such as an auxiliary burner, a turbine exhaust throttle, a bypass around the recuperative heat exchanger as well as nitrogen and hydrogen supply and mixing units are required. Therewith, smooth cooling/heating of the cell can be accomplished without external electric power, but with a considerable amount of fuel and flushing nitrogen required.

A further analysis investigates fuel flexibility of a system designed for methane: Hydrogen can be utilised without larger system modifications; only the control system characteristics must be adapted. Because no endothermic steam reforming takes place, the power output is, however, reduced to 70% of the original value, and efficiency is reduced to 55%. Applying the additional equipment required for shutdown/startup, the power can be increased to 94% of the original value, although at a further efficiency decrease. In order to use ethanol as fuel in the ejector-driven anode, a recuperative vaporiser must be applied in the fuel channel. Supposed that reliable reforming catalysts for ethanol can be provided, 88% of the original power output can be achieved at a high efficiency of 62%.

The investigation of the other cycle options reveals that a two turbine cycle where the power turbine is rotating at constant speed, mostly differs in terms of controllability. For controlling the air flow, another handle such as variable inlet guide vanes or air bypass around the SOFC system is required. The indirectly integrated SOFC cycle (IIC) has a significantly lower efficiency of only 56%, assuming the SOFC at the same temperature level than in the DIC.

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35

Kocian, Martin Lukas. "Das Lichtpulsersystem des elektromagnetischen CsI(Tl)-Kalorimeters des Babar-Detektors". Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2000. http://nbn-resolving.de/urn:nbn:de:swb:14-994685405218-39354.

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A light pulser system for the Babar CsI(Tl) calorimeter, capable of monitoring the light yield of the 6580 crystals and of checking the function and linearity of the readout electronics, was developed in a collaboration with groups from Bochum and Edinburgh. The light pulser system is based on the coupling of light from Xenon flashlamps through optical fibers into the individual crystals. The absolute intensity is measured by two special reference systems whose stability is monitored using a radioactive source. During the construction phase the light pulser was used to check the electronics in order to ensure its functioning before the insertion of the calorimeter into the detector where the preamplifier electronics is inaccessable for repair. In monitoring the short term performance of the light pulser system, the stability over one week is better than 0.15 %. Over six months between February and August 2000 the crystal response, as measured by the light pulser, of the three rings of the endcap that are closest to the beam dropped by up to 2 % in comparison with the three outer rings of the endcap, due to radiation damage. Through linearity measurements with the light pulser a flaw in the ADC boards of the calorimeter electronics, which will be fixed in the near future, and cross-talk between channels was found. By a software correction of these effects implemented by members of the collaboration an improvement of the energy resolution of the calorimeter was achieved
Fuer das CsI(Tl)-Kalorimeter des Babar-Detektors wurde in Zusammenarbeit mit Gruppen aus Bochum und Edinburgh ein Lichtpulsersystem entwickelt, das in der Lage ist, die Lichtausbeute der 6580 Kristalle zu monitorieren und die Funktionsfaehigkeit und Linearitaet der Kalorimeterelektronik zu ueberpruefen. Das Lichtpulsersystem basiert auf der Einkopplung des Lichts von Xenon-Blitzlampen ueber Lichtleitfasern in einzelne Kristalle. Die absolute Lichtmenge wird durch zwei spezielle Lichtnormale gemessen, deren Stabilitaet durch eine radioaktive Quelle monitoriert wird. In der Aufbauphase kam der Lichtpulser fuer die Ueberpruefung der Elektronik zum Einsatz, um deren Funktionsfaehigkeit sicherzustellen, bevor das Kalorimeter in den Detektor eingebaut wurde, weil danach die Vorverstaerkerelektronik fuer Reparaturen nicht mehr zugaenglich war. In der Monitorierung ist die Kurzzeitstabilitaet des Lichtpulsersystems ueber eine Woche besser als 0,15 %. Ueber sechs Monate zwischen Februar und August 2000 sank, bedingt durch Strahlenschaeden, die mit dem Lichtpulser gemessene Antwort der Kristalle fuer die strahlnaechsten drei Ringe der Endkappe um bis zu 2 % staerker als in den aeusseren drei Ringen der Endkappe. Durch die Linearitaetsmessungen mit dem Lichtpulser konnte ein Fehler in der Kalorimeterelektronik im Bereich der ADC-Karten, der in naher Zukunft behoben werden wird, sowie ein Uebersprechen zwischen den Kanaelen gefunden werden. Durch Softwarekorrekturen dieser Effekte von seiten der Kollaboration konnte eine Verbesserung der Energieaufloesung des Kalorimeters erreicht werden
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36

Gramlich, Ludwig. "Die Deutsche Bundesbank in neuer Gestalt - Zur Vierten Novellierung des Bundesbankgesetzes". Universitätsbibliothek Chemnitz, 2009. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-200900171.

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Die Vierte Novellierung des Bundesbankgesetzes im Jahr 1992 zielte in erster Linie auf eine Bereinigung der temporären Sondersituation der Zentralbankorganisation in den "Neuen Bundesländern", brachte aber darüber hinaus eine Verschlankung der Strukturen der Bundesbank und einige weitere materielle Änderungen des Bundesbankgesetzes. Der Beitrag gibt zugleich eine erste Einschätzung des Anpassungsbedarfs bei Errichtung der im Maastricht-Vertrag vorgesehenen Wirtschafts- und Währungsunion.
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37

Almisbah, Abdulghani Jaafar. "Investigating the adoption of Interactive Complex Intervention Model (ICIM) aiming at reforming the Bahrain governmental performance as an example of Islamic contexts". Thesis, Brunel University, 2017. http://bura.brunel.ac.uk/handle/2438/15838.

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There is a consensus within the United Nations (UN), as well as various governmental entities, politicians, individuals, scholars, and academic communities, on the need to reform governmental performances. However, there is no unanimity among them pertaining to a specific reforming model that is valid for all contexts worldwide. Accordingly, many performance management processes and practical techniques have been put into practice, which aim at improving governmental institutions' performance. Hence, the purpose of this research is to develop, by studying the public health services that are provided by the government, an effective model, with the aim of improving governmental performance in the context of Bahrain. With regard to originality and values, the research discerns that among the many factors affecting governmental entities' performance, there are two dominant contextual factors, i.e. the sociocultural and political forces, both of which synergise with the so-called United Nations Development Programme (UNDP) Good Governance Approach. The study develops a new perspective on the Interactive Complex Intervention Model (ICIM), stemming from the Grounded Theory (GT) and Normalisation Process Theory/Model (NPT/M), as disclosed in practical terms by the outcomes of the data gathered and its analysis. In fact, although those elements influence all other factors, there are interactive correlative impacts among all factors. Despite these outcomes, the data obtained from the research cannot be generalised, as they are derived from the local context of Bahrain; certainly until now, they can allow other similar contexts in particular to implement the insights reported in this study. It is important to note that the most influencing factor enabling this research, which aims to develop the ICIM for reforming governmental entities' performance in Bahrain, is the salient points raised in Imam Ali's famous consultative letter to the Governor of Egypt, Malik Ashtar, which he wrote while he was the Caliph, as scholars regard this letter as a basic guide for the Islamic administration and the UNDP Good Governance Approach. Regarding the practical implications, the research has attempted to empirically understand the role of the aforementioned primary contributing forces, that are regarded as the critical prerequisite - the first step that allows the governments' decision makers, based on the underlying knowledge involved in the work, to forthwith provide them with several contextual practical insights towards adopting the ICIM in order to enhance and reform the government entities' performance.
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38

Löser, Jork. "Low-Latency Hard Real-Time Communication over Switched Ethernet". Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2006. http://nbn-resolving.de/urn:nbn:de:swb:14-1138799484082-54477.

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With the upsurge in the demand for high-bandwidth networked real-time applications in cost-sensitive environments, a key issue is to take advantage of developments of commodity components that offer a multiple of the throughput of classical real-time solutions. It was the starting hypothesis of this dissertation that with fine grained traffic shaping as the only means of node cooperation, it should be possible to achieve lower guaranteed delays and higher bandwidth utilization than with traditional approaches, even though Switched Ethernet does not support policing in the switches as other network architectures do. This thesis presents the application of traffic shaping to Switched Ethernet and validates the hypothesis. It shows, both theoretically and practically, how commodity Switched Ethernet technology can be used for low-latency hard real-time communication, and what operating-system support is needed for an efficient implementation.
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39

Simeone, Bruno. "Mathematics and democracy recent advances in voting systems and collective choice ; with 50 tables". Berlin Heidelberg New York Springer, 2006. http://deposit.d-nb.de/cgi-bin/dokserv?id=2841845&prov=M&dok_var=1&dok_ext=htm.

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40

Kandel, Sangam, Devaiah P. Shivakumar i Cecelia A. McIntosh. "Biochemical Characterization of a Cp-3-O-GT Mutant P145T and Study of the Tag Effect on GT Activity". Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/359.

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Flavonoids are a class of secondary metabolites, the majority of which are present in glucosylated form. Glucosyltransferases catalyze glucosylation by transferring glucose from UDP-activated sugar donor to the acceptor substrates. This research is focused on the study of the effect of a single point mutation on enzyme activity, characterization of a flavonol specific 3-O-glucosyltransferase (Cp-3-O-GT) mutant- P145T, and further modification of the clone to cleave off tags from recombinant wild type and P145T mutant proteins in order to crystallize the proteins. Multiple sequence alignment and homology modeling was done to identify candidate residues for mutation. Cp-3-O-GT was modeled with a flavonoid 3-O-GT from Vitis vinifera (VvGT) that can glucosylate both flavonols and anthocyanidins. We identified a proline residue at position 145 of Cp-3-O-GT that corresponded to a threonine residue in VvGT and designed a Cp-3-O-GTP145T mutant to test the hypothesis that that mutation of proline by threonine in Cp-3-O-GT could alter substrate or regiospecificity of Cp-3-O-GT. While the mutant P145T enzyme did not glucosylate anthocyanidins, it did glucosylate flavanones and flavones in addition to flavonols. This is significant because flavanones and flavones do not contain a 3-OH group. HPLC was performed to identify the reaction products. Early results indicated that the mutant protein glucosylates naringenin at the 7-OH position forming prunin. Results are being used to revisit and refine the structure model. In other related work, a thrombin cleavage site was inserted into wild type and recombinant P145Tenzyme and we are currently working on transformation into yeast for recombinant protein expression. Cleaving off tags is a pre-requisite to future efforts to crystallize the proteins. Solving the crustal structures will make a significant contribution to the structural and functional study of plant flavonoid GTs in general and Cp-3- O-GT in particular.
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41

Löser, Jork. "Low-Latency Hard Real-Time Communication over Switched Ethernet". Doctoral thesis, Technische Universität Dresden, 2005. https://tud.qucosa.de/id/qucosa%3A24637.

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With the upsurge in the demand for high-bandwidth networked real-time applications in cost-sensitive environments, a key issue is to take advantage of developments of commodity components that offer a multiple of the throughput of classical real-time solutions. It was the starting hypothesis of this dissertation that with fine grained traffic shaping as the only means of node cooperation, it should be possible to achieve lower guaranteed delays and higher bandwidth utilization than with traditional approaches, even though Switched Ethernet does not support policing in the switches as other network architectures do. This thesis presents the application of traffic shaping to Switched Ethernet and validates the hypothesis. It shows, both theoretically and practically, how commodity Switched Ethernet technology can be used for low-latency hard real-time communication, and what operating-system support is needed for an efficient implementation.
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42

Kandepu, Rambabu. "Control Relevant Modeling and Nonlinear State Estimation Applied to SOFC-GT Power Systems". Doctoral thesis, Norwegian University of Science and Technology, Department of Engineering Cybernetics, 2007. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-1797.

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With today’s increasing concern about global warming and climate change and further increase in energy demand, there is an incentive to investigate power processes that operate efficiently, and thus reducing the amount of emitted pollutants per produced energy unit. It is widely accepted that fuel cells are power sources that will become increasingly important, due to high efficiency, low levels of pollution and noise, and high reliability. A fuel cell converts chemical energy in a fuel directly to electrical energy without direct combustion. One of the most promising fuel cell technologies is the Solid Oxide Fuel Cell (SOFC), due to its solid state design and internal reforming of gaseous fuels, in addition to its high efficiency. Since SOFCs operate at high temperatures (about 1000◦C), natural gas can be used directly as fuel. The electrical efficiency of a SOFC can reach 55%. Another significant advantage of the SOFC is that since it operates at high temperature and its efficiency increases when pressurized, it naturally lends itself as a heat source for a gas turbine (GT) cycle. The combined (hybrid) cycle can theoretically have an overall electrical efficiency of up to 70% with a power range from a few hundred kWs to a few MWs. The main applications of the hybrid system include remote area power supply and distributed power generation.

To understand the process dynamics and further to design a control structure, it is useful to have a control relevant model of the hybrid system. The first part of the thesis focuses on developing control relevant models of all the components of the SOFC-GT hybrid system using first principles. The SOFC model developed is tested against a very detailed model and the results show that the control relevant model captures the dynamics of the process and thus can be used to design a control structure. Next, a regulatory controller is designed in order for the hybrid system to be able to follow the dynamic load changes while SOFC temperature is controlled.

In a SOFC-GT system, as well as many other process systems, state estimation may be important for monitoring and control. Thus, the final part of the thesis concentrates on nonlinear state estimation. The Unscented Kalman Filter (UKF) is investigated for the state estimation in comparison with Extended Kalman Filter (EKF). One of the results is a simple and promising constraint handling method for UKF.


Article I: ©2006 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE. Article II: ©2007 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.
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43

Breuer, Judith. "Aufnahme, Metabolismus und Bildung nicht-extrahierbarer Rückstände aus 4-Nitrophenol in Soja und Weizen ein Vergleich verschiedener In-vitro-Systeme /". Aachen : Shaker, 2002. http://deposit.d-nb.de/cgi-bin/dokserv?idn=964993554.

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Rigby-Smith, Martin. "Säg att du är min syster : En narrativ analys med feministisk kritik av berättelserna i Genesis 12, 20 och 26 och av den utsatta kvinnan som motiv". Thesis, Uppsala universitet, Teologiska institutionen, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-202444.

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45

Rottleb, René. "Das Paradigma des homogenen Enterprise Access Managements sowie ein Vorschlag zur unternehmensweit konsistenten Zugriffssteuerung". Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2003. http://nbn-resolving.de/urn:nbn:de:swb:14-1071583567796-84449.

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Bei der Umsetzung moderner Managementkonzepte wie bspw. Supply Chain Management, Customer Relationship Management und Partner Relationship Management werden Anwendungssysteme wertschöpfungskettenübergreifend eingesetzt. Das bedeutet, dass sowohl interne als auch externe Benutzer auf verschiedene Anwendungssysteme eines Unternehmens zugreifen. Die daraus resultierenden Anforderungen werden als Paradigma des homogenen Enterprise Access Managements (hEAM) beschrieben. Zur Umsetzung dieser Anforderungen wird ein Referenzmodell zur anwendungssystemübergreifend konsistenten Zugriffssteuerung (MAKS) entwickelt. Eine entsprechende Realisierungsmöglichkeit in Form eines zentralen Rollen- und Rechtemanagementsystems (ZR2MS) ergibt sich aus der Referenzarchitektur zur anwendungssystemübergreifend konsistenten Zugriffssteuerung (A2KS).
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Popp, Nicole. "Community structure and degradation potential in bioremediation systems treating contaminated soils". Doctoral thesis, Technische Universitaet Bergakademie Freiberg Universitaetsbibliothek &quot;Georgius Agricola&quot, 2009. http://nbn-resolving.de/urn:nbn:de:bsz:105-5122728.

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Mit Mineralölkohlenwasserstoffen (MKWs) kontaminierte Böden stellen ein weitverbreitetes Umweltproblem dar. Da Böden ein wertvolles Schutzgut darstellen und nur über lange Zeit erneuerbar sind, existieren verschiedenste Sanierungsmaßnahmen, um den Boden wieder nutzbar zu machen. Die off-site Sanierung in Form von Bodenmieten ist dabei die am häufigsten angewendete Sanierungsmethode. Bei diesem Verfahren werden die Mieten, um eine optimale Sauerstoff- und Nährstoffversorgung der autochtonen Mikroflora zu gewährleisten, während des gesamten Sanierungsprozesses belüftet und ggf. zu Beginn mit Mineraldünger versetzt. Die Zugabe von Fremdorganismen mit entsprechendem Abbaupotential führte in solchen Fällen meist nicht zu einem gesteigerten Sanierungserfolg. Die zu einem Zeitpunkt gegebene Abbauaktivität der Organismen kann über die Messung der Temperatur im Mieteninneren abgeschätzt werden. Ansonsten werden Bodenreinigungsverfahren hinsichtlich der Mikrobiologie bisher als &quot;black box&quot; betrieben. Da bisher noch wenig über die mikrobielle Diversität aktiver Bodenmieten und das im Boden vorhandene Abbaupotential bekannt ist, sollte die Anwendung molekulargenetischer Methoden Aufschluss darüber geben. Die Charakterisierung der aktiven Mikroflora erfolgte zunächst durch die Klonierung der cDNA der 16S rRNA, da durch die 16S rRNA fast ausschließlich Mikroorganismen mit aktiver Proteinsynthese nachgewiesen werden. Die dabei als häufig charakterisierten Gattungen wurden über den gesamten Sanierungsverlauf mittels Membranhybridisierung quantifiziert. Die DNA-Sonden dafür wurden entweder selbst entworfen oder aus der Literatur übernommen. Der Nachweis des Abbaupotentials erfolgte anhand der Gene für die Schlüsselenzyme Alkan-Hydroxylase (AlkB) und Catechol-2,3-Dioxygenase (C23O). Die Quantifizierung der Abbaugene wurde auf DNA-Ebene mit Hilfe der kompetitiven PCR mit einem internen Standard durchgeführt. Das in der Arbeit untersuchte Bodenmaterial stammt aus dem Teerverarbeitungswerk Rositz. Es standen davon drei Mieten mit unterschiedlicher Konzentration an MKW zur Verfügung. Das Material von Rositz 3 wurde über den gesamten Sanierungsverlauf beprobt. Eine Probe der aktiven Miete Rositz 3 wurde zur Diversitätsanalyse herangezogen. Die Mieten Rositz 1 und Rositz 2 sowie das Mietenausgangsmaterial der Tanklager Grimma und Espenhain dienten zu Vergleichsuntersuchungen. Mit der verwendeten Methode zur Nukleinsäure-Extraktion war es möglich, gleichzeitig die RNA und die DNA einer Probe zu erhalten. Die nach Aufschluss mit Glaskugeln erhaltenen sequentiellen Extrakte 1 und 2/3 wurden getrennt voneinander weiter untersucht. Im 1. Aufschluss wurden vermutlich bevorzugt die Mikroorganismen extrahiert, die sich an der Oberfläche der Bodenpartikel befanden, und im 2./3. die aus dem Innern der Bodenpartikel. Die Sequenzierung der SSU rRNA zeigte eine relativ hohe Diversität der Mikroflora, wobei allerdings beide Klonbanken der sequentiellen Nukleinsäureextrakte von den Gammaproteobakterien, besonders von Pseudomonaden dominiert wurden. Die Dominanz der Gammaproteobakterien kann auf das Phänomen des ‚gamma-shifts’ zurückgeführt werden. Aufgrund der hohen MKW-Konzentration im Bodenmaterial, was für die zum Abbau fähigen Bakterien ein hohes Substratangebot darstellt, fand möglicherweise eine Anreicherung der Gammaproteobakterien statt. Alpha- und Betaproteobakterien stellten ebenfalls zwei weitere große Gruppen in den Klonbanken dar. Die erhaltenen Sequenzen waren häufig ähnlich zu denen von kultivierten Mikroorganismen, bildeten in den Dendrogrammen jedoch eigene Cluster, wobei die ähnlichsten Sequenzen meist aus Bodenuntersuchungen stammen. Eine Ausnahme stellen dabei die zu den gefundenen Betaproteobakterien ähnlichen Sequenzen dar. Sie waren vor allem in aquatischen Ökosystemen dominierend. Interessant war, dass manche Gattungen, wie Sphingomonaden oder Zymomonas spp. nur in einem der beiden sequentiellen RNA-Extrakte nachgewiesen werden konnten. Gattungen, wie Acidovorax spp., konnten in beiden Extrakten detektiert werden, wobei die Sequenzen der einzelnen sequentiellen Extrakte im Dendrogramm häufig separate Cluster bildeten. Für alle detektierten Gattungen sind Vertreter bekannt, die in der Lage sind, Bestandteile von MKW abzubauen. Der Vergleich der Sequenzen zeigte, dass der Schadstoffbau hauptsächlich an der Oberfläche der Bodenpartikel stattfinden muss, da viele ähnliche Sequenzen des 2./3. Aufschlusses unter mikroaeroben Bedingungen gefunden wurden. Für die Quantifizierung der dominierenden Gattungen mittels Membranhybridisierung konnten Sonden für Pseudomonas, Sphingomonas, Acinetobacter und Acidovorax aus der Literatur übernommen werden. Auf der Basis der Sequenzdaten wurden für die Gattungen Rhodoferax, Thiobacillus und für die zum Klon TRS13 ähnlichen Sequenzen drei neue &quot;Rositz&quot;–Sonden entwickelt. Im 1. Extrakt war der Anteil der einzelnen Gattungen in den meisten Fällen jeweils höher als im 2./3. Extrakt. Sphingomonaden und Thiobacillen konnten in allen Phasen des Abbauprozesses nachgewiesen werden. Alle anderen genannten Gattungen waren zumeist nur zu Beginn und während des frühen aktiven Schadstoffabbaus detektierbar. Es konnte dabei ein besonders hoher Anteil an Sphingomonaden, Pseudomonaden und Rhodoferax spp. nachgewiesen werden. Das Verschwinden der Pseudomonaden nach der schnellen Abbauphase, d.h. nach dem Abbau der gut bioverfügbaren Schadstoffe, ist ein bekanntes Phänomen. Schlecht bioverfügbare Verbindungen werden wahrscheinlich von anderen Gattungen abgebaut, die aber in dieser Arbeit nicht identifiziert worden sind. Die drastische Änderung der mikrobiellen Gemeinschaft wurde in dieser Form nicht erwartet. Die Schadensfälle Rositz 1 und Rositz 2 wiesen einen geringeren Anteil an Pseudomonaden auf als Rositz 3. Am Ende des Sanierungsprozesses konnten in diesen beiden Mieten auch noch mehr von den detektierten Gattungen nachgewiesen werden. Die Gattung Acinetobacter konnte nur zu Beginn der Sanierung und der aktiven Phase der Miete Rositz 1 detektiert werden, was möglicherweise auf ein Sondenproblem zurückzuführen ist. Die ausgewählten Abbaugene konnten in relativ konstanter Menge über den gesamten Abbauprozess im Bodenmaterial von Rositz 1 und Rositz 3 nachgewiesen werden. In der Miete Rositz 2 war die Kopienzahl der Abbaugene zu Beginn der Sanierung geringer als im aktiven Bodenmaterial, was die Entwicklung der abbauenden Gemeinschaft während des Sanierungsprozesses zeigt. Die Kopienzahl für AlkB lag in allen Fällen deutlich über denen für C23O. Dies ist vermutlich darauf zurückzuführen, dass im Schadensfall Rositz die Alkane den Hauptteil der Kontamination ausmachten. In den meisten Fällen wurde im 1. Extrakt eine höhere Kopienzahl für AlkB und C23O nachgewiesen als im 2./3. Extrakt. Anhand der verwendeten Nachweismethode lässt sich also schlussfolgern, dass sich die meisten zum MKW-Abbau fähigen Mikroorganismen auf der Oberfläche der Bodenpartikel befanden. Trotz unterschiedlicher MKW-Ausgangskonzentration und Sanierungsdauer unterschieden sich die Schadensfälle Grimma und Espenhain kaum in der ermittelten Kopienzahl für AlkB und C23O sowie im Anteil der nachgewiesenen Gattungen. Es sind auch nur geringe Unterschiede zu den Rositz-Mieten erkennbar. In den zu sanierenden Böden liegt ein ausreichend hohes Abbaupotential vor. Der limitierende Faktor für eine erfolgreiche Sanierung scheint demzufolge die ausreichende Sauerstoffversorgung der zum Abbau befähigten Mikroorganismen zu sein.
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47

Rottleb, René. "Das Paradigma des homogenen Enterprise Access Managements sowie ein Vorschlag zur unternehmensweit konsistenten Zugriffssteuerung". Doctoral thesis, Technische Universität Dresden, 2002. https://tud.qucosa.de/id/qucosa%3A24282.

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Bei der Umsetzung moderner Managementkonzepte wie bspw. Supply Chain Management, Customer Relationship Management und Partner Relationship Management werden Anwendungssysteme wertschöpfungskettenübergreifend eingesetzt. Das bedeutet, dass sowohl interne als auch externe Benutzer auf verschiedene Anwendungssysteme eines Unternehmens zugreifen. Die daraus resultierenden Anforderungen werden als Paradigma des homogenen Enterprise Access Managements (hEAM) beschrieben. Zur Umsetzung dieser Anforderungen wird ein Referenzmodell zur anwendungssystemübergreifend konsistenten Zugriffssteuerung (MAKS) entwickelt. Eine entsprechende Realisierungsmöglichkeit in Form eines zentralen Rollen- und Rechtemanagementsystems (ZR2MS) ergibt sich aus der Referenzarchitektur zur anwendungssystemübergreifend konsistenten Zugriffssteuerung (A2KS).
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48

Dinesen, Timothy R. J. "Application of density matrix theory to dynamical problems in the nuclear magnetic resonance of I>12 spin systems displaying orientational anisotropy". Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=40339.

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La theorie de la matrice de densite est utilisee pour obtenir une representation theoretique de la Resonance Magnetique Nucleaire (RMN) effectuee sur deux systemes differents, les deux menant a dence de "l'anisotropy orientational". Le premier cas examine la "Multiple Quantum Filtered" (MQF) ligne en forme de $ sp{23}$Na (I = 3/2) tel qu'observe recemment dans certains tissus biologiques. On peut remenquer la relaxation en utilisant la theorie de Redfield. La production de la contribution d'un tenseur de deuxieme ranq a la forme de la ligne est demontee etre directment attributable a la presence d'une constante de copulation quadrupole electrique qui ne disparant pas. Les equations des mouvements derivees pour I = 3/2 peuvent etre appliquees a une sequence general de pouls et une solution specifiques pour l'experience DQF est discutee. Le deuxieme cas recherche le signal reponse de o-D$ sb2$ (avec impulsion angulaire rotationalle J = 0 et le spin angulaire I = 2) et p-D$ sb2$ (avec J = 1 et I = 1) dans les experiences RMN consistant dans une sequence a deux pouls. L'amplitude prevue de l'echo solide pur les contributions de I = 1 et I = 2 est exprimee par une fraction molaire, les parametres du pouls, l'intervalle entre les deux pouls, le champs moyen dipolaire de la pair de spin et le champs non-homogene magnetique. Les proprietes de l'hydrogene solide sont discutees dans le contexte de l'experience de l'echo solide. Pour la fraction I = 2, les positions prevues pour les echos satellites sont determinees ainsi que l'impossibilite de les observer en D$ sb2$ solide est discutees en termes des granduers relative des constantes de copulation intramoleculaire et du champs non-homogene magnetique.
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49

Pralavorio, Pascal. "Violation de cp dans le systeme b-b : > avec le detecteur cms a lhc et etude des chambres gazeuses a micropistes". Université Louis Pasteur (Strasbourg) (1971-2008), 1997. http://www.theses.fr/1997STR13046.

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Cette these s'inscrit dans le cadre de la preparation du detecteur cms aupres du futur collisionneur lhc au cern, dont la mise en service est prevue pour les annees 2004-2005. Le travail est divise en deux parties. La premiere partie comprend une etude generale sur l'identification des electrons de faible energie en utilisant la tres fine granularite et la tres bonne resolution en energie du calorimetre electromagnetique de cms. L'efficacite de l'algorithme est de 60% et le facteur de rejection des hadrons est de 400. Les electrons ainsi identifies peuvent etre utilises comme des particules d'etiquetage pour les mesons beaux ou pour reconstruire les decroissances inclusives b#d / ( e#+e#-) + x. La reevaluation de la sensibilite aux angles et b du triangle ckm d'unitarite avec ces nouvelles possibilites et des fonctions de structure du proton recentes donne: (sin 2) = 0. 06#+#0#. #0#1#8#-#0#. #0#1#4 (sin 2b) = 0. 053#+#0#. #0#1#7#-#0#. #0#1#2. Ces resultats sont comparables avec ceux attendus par les experiences dediees a la physique du b. La deuxieme partie a consiste a developper un nouveau type de chambres gazeuses a micropistes (mgc) ou les anodes sont separees d'un plan cathode par une couche isolante de quelques microns. Cette geometrie permet une collection rapide des charges ( 10 ns), d'atteindre des gains superieurs a 3000 et d'avoir une resolution en energie de 20% pour le pic d'une source de #5#5fe
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Sergent, Aaronn. "Optimal Sizing and Control of Battery Energy Storage Systems for Hybrid-Electric, Distributed-Propulsion Regional Aircraft". The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1595519141013663.

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