Gotowa bibliografia na temat „Finistère (Department)”

Aim of study: The effect of cerium oxide engineered nanoparticles on the spore germination of the fern. Asplenium adiantum-nigrum.Area of study: France, Britanny Region, Finistére Department, Plougonvelin, in rocks near the sea.Material and methods: Asplenium spores were cultured in vitro on agar medium with Nano-CeO2 (less than 25 nm particle size) and bulk-CeO2. The addition of each nano- and bulk particles ranged from 0 to 3000 mg L-1. Observations on rhizoidal and prothallial cells during first stages of gametophyte development were made. The No-Observed-Adverse-Effect concentration (NOAEC) and Lowest-Observed-Adverse-Effect-Concentration (LOEC) values for spore germination rate data were analyzed. Main results: Germination was speeded up by 100 to 2000 mg L-1 nanoceria, while bulk cerium oxide had the same effect for 500 to 200 mg L-1 concentrations. Present results showed cellular damage in the protonema while rhizoid cells seemed not to be affected, as growth and membrane integrity remained.Research highlights: Both nanosized and bulk cerium oxide are toxic for the fern Asplenium adiantum-nigrum, although diverse toxicity patterns were shown for both materials. Diverse toxic effects have been observed: chloroplast membrane damage and lysis, cell wall and membrane disruption which leads to cell lysis; and alterations in morphology and development.Keywords: Nanoparticles; rhizoid; prothallus; chloroplast; fern.

Abstract Background With large demonstrated benefits, volume of bariatric surgery (BS) has increased almost threefold since the late 2000s in France. However, patients seeking for BS must be carefully preoperatively evaluated to reduce risks for late complications (nutritional, neurological and psychiatric). This study aimed to assess preoperative evaluation of BS according to French recommendations. Methods The preoperative evaluation (gastrointestinal, nutritional, cardiovascular and psychiatric) during the year preceding BS was assessed from the French national health insurance database. All patients with a primary BS in Brittany in 2015 were included. For each patient, a score of preoperative evaluation was carried-out (from 0 to 6) and classified as follows: “complete” (6), “incomplete” (4-5), “unsatisfactory” (2-3) or “poor” (0-1). Comparisons (chi-square tests) by sex, geographical department, type of institution and health professionals (HP) were made. Results Among the 1,446 patients finally included, 1,195 (83%) were women and the median age was 42 (quartiles: 33-51) years old. Gastric by-pass (66%) and sleeve-gastrectomy (33%) were the most performed procedure. The preoperative evaluation was classified as ’complete’ for 501 (35%) patients, ’incomplete’ for 647 (45%) patients, ’unsatisfactory’ for 238 (17%) patients, and ’poor’ for 60 (4%) patients. Better scores were found in 2 departments (Côtes d’Armor and Finistère, p < 0.001), in public institutions (p < 0.001) and in institutions performing 50 or more acts per year (p < 0.001). Heterogeneity according to the HP was also noted in private institutions (median score per HP: 4.5, min-max: 2-6). Conclusions This large regional comprehensive French study confirms that preoperative evaluation before BS is not optimal despite clear French recommendations. Collective reflection should be led to improve the pathway of care of patients seeking BS. Key messages There are disparities in the performance of BS’s preoperative evaluation in Brittany. This work suggests that preoperative evaluation for patients seeking for BS should be improved and standardized.