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Artykuły w czasopismach na temat „FG7142”

Autor: Grafiati
Data publikacji: 4 czerwca 2021
Data aktualizacji: 4 lutego 2022

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Sprawdź 31 najlepszych artykułów w czasopismach naukowych na temat „FG7142”.

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1

Garfield, Joshua B. B., i Gavan P. McNally. "The effects of FG7142 on overexpectation of Pavlovian fear conditioning." Behavioral Neuroscience 123, nr 1 (2009): 75–85. http://dx.doi.org/10.1037/a0013814.

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Peris, Joanna, i James D. Scott. "FG7142 causes opposite changes in [3H]GABA release from nigrocollicular regions". Pharmacology Biochemistry and Behavior 44, nr 2 (luty 1993): 333–38. http://dx.doi.org/10.1016/0091-3057(93)90470-e.

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Little, H. "Chronic benzodiazepine treatment increases the effects of the inverse agonist FG7142". Neuropharmacology 27, nr 4 (kwiecień 1988): 383–89. http://dx.doi.org/10.1016/0028-3908(88)90147-5.

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Glushankov, P. G., V. S. Vorob'ev i V. G. Skrebitskii. "Effect of the ?-carboline derivative FG7142 on inhibition in hippocampal slices". Bulletin of Experimental Biology and Medicine 100, nr 6 (grudzień 1985): 1715–18. http://dx.doi.org/10.1007/bf00836318.

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5

Murphy, B. "Clozapine Reverses the Spatial Working Memory Deficits Induced by FG7142 in Monkeys". Neuropsychopharmacology 16, nr 6 (czerwiec 1997): 433–37. http://dx.doi.org/10.1016/s0893-133x(97)00019-5.

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Major, Christine A., Brian J. Kelly, Melinda A. Novak, Matthew D. Davenport, Karen M. Stonemetz i Jerrold S. Meyer. "The anxiogenic drug FG7142 increases self-injurious behavior in male rhesus monkeys (Macaca mulatta)". Life Sciences 85, nr 21-22 (listopad 2009): 753–58. http://dx.doi.org/10.1016/j.lfs.2009.10.003.

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Takamatsu, Hiroyuki, Akihiro Noda, Akeo Kurumaji, Yoshihiro Murakami, Mitsuyoshi Tatsumi, Rikiya Ichise i Shintaro Nishimura. "A PET study following treatment with a pharmacological stressor, FG7142, in conscious rhesus monkeys". Brain Research 980, nr 2 (sierpień 2003): 275–80. http://dx.doi.org/10.1016/s0006-8993(03)02987-1.

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Tang, Helen H. Y., Gavan P. McNally i Rick Richardson. "The effects of FG7142 on two types of forgetting in 18-day-old rats." Behavioral Neuroscience 121, nr 6 (2007): 1421–25. http://dx.doi.org/10.1037/0735-7044.121.6.1421.

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Kurumaji, Akeo, Takashi Ito, Sumikazu Ishii i Toru Nishikawa. "Effects of FG7142 and immobilization stress on the gene expression in the neocortex of mice". Neuroscience Research 62, nr 3 (listopad 2008): 155–59. http://dx.doi.org/10.1016/j.neures.2008.08.001.

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Birnbaum, S. G., D. M. Podell i A. F. T. Arnsten. "Noradrenergic alpha-2 receptor agonists reverse working memory deficits induced by the anxiogenic drug, FG7142, in rats". Pharmacology Biochemistry and Behavior 67, nr 3 (listopad 2000): 397–403. http://dx.doi.org/10.1016/s0091-3057(00)00306-3.

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11

Taylor, Stuart C., Amanda L. Johnston, Lucy J. Wilks, Jane M. Nicholass, Sandra E. File i Hilary J. Little. "Kindling with the β-Carboline FG7142 Suggests Separation between Changes in Seizure Threshold and Anxiety-Related Behaviour". Neuropsychobiology 19, nr 4 (1988): 195–201. http://dx.doi.org/10.1159/000118460.

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12

Stanford, S. C., D. Gettins i H. J. Littel. "Adverse effects on rat cardiac function ex vivo after repeated administration of the benzodiazepine partial inverse agonist, FG7142". British Journal of Pharmacology 99, nr 3 (marzec 1990): 441–44. http://dx.doi.org/10.1111/j.1476-5381.1990.tb12946.x.

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Ferretti, Valeria, Paola Gilli i Pier Andrea Borea. "Structural features controlling the binding of β-carbolines to the benzodiazepine receptor". Acta Crystallographica Section B Structural Science 60, nr 4 (19.07.2004): 481–89. http://dx.doi.org/10.1107/s0108768104013564.

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Streszczenie:
β-Carbolines are a class of drug which can interact with a high affinity with the benzodiazepine (BDZ) binding site of the GABAA receptor. The present paper, aimed at obtaining a deeper insight into the structure–properties relationships of this class of molecules, reports the crystal structures of four β-carbolines: ZK93423 (3-carboethoxy-4-methoxymethyl-6-benzyloxy-β-carboline), ZK91296 (3-carboethoxy-4-methoxymethyl-5-benzyloxy-β-carboline), FG7142 (N-methyl-3-carbamoyl-β-carboline) and the low-affinity ligand harmine hydrochloride (1-methyl-7-methoxy-β-carboline). This set of structural data is completed by the X-ray structures of other carbolines of known biological activity retrieved from the Cambridge Crystallographic Database and by the structures of β-CCE (3-carboethoxy-β-carboline), 6-PBC (3-carboethoxy-4-methoxymethyl-6-isopropoxy-β-carboline), PRCC (3-isopropoxy-β-carboline) and ZK93426 (3-carboethoxy-4-methyl-5-isopropoxy-β-carboline), which have been obtained by molecular-mechanics simulations. The structural features of all these molecules have been compared according to the stereochemical model we proposed in 1987. The structural comparison is integrated by the Free–Wilson analysis on 32 β-carbolines of known binding affinity data.
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14

Kohno, Shin-ichi, Kinzo Matsumoto, Kazuma Ojima i Hiroshi Watanabe. "Flumazenil but not FG7142 attenuates the decrease in pentobarbital sleep produced by activation of central noradrenergic systems in mice". Japanese Journal of Pharmacology 73 (1997): 171. http://dx.doi.org/10.1016/s0021-5198(19)45185-8.

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15

Matsumoto, Kinzo, Shin-Ichi Kohno, Kazuma Ojima i Hiroshi Watanabe. "Flumazenil but not FG7142 reverses the decrease in pentobarbital sleep caused by activation of central noradrenergic systems in mice". Brain Research 754, nr 1-2 (kwiecień 1997): 325–28. http://dx.doi.org/10.1016/s0006-8993(97)00176-5.

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16

Dazzi, Laura, Stefania Ladu, Francesca Spiga, Giada Vacca, Antonella Rivano, Luigi Pira i Giovanni Biggio. "Chronic treatment with imipramine or mirtazapine antagonizes stress- and FG7142-induced increase in cortical norepinephrine output in freely moving rats". Synapse 43, nr 1 (30.11.2001): 70–77. http://dx.doi.org/10.1002/syn.10024.

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Casarrubea, Maurizio, Giuseppe Di Giovanni i Giuseppe Crescimanno. "Effects of Different Anxiety Levels on the Behavioral Patternings Investigated through T-pattern Analysis in Wistar Rats Tested in the Hole-Board Apparatus". Brain Sciences 11, nr 6 (27.05.2021): 714. http://dx.doi.org/10.3390/brainsci11060714.

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The Hole-Board is an ethologically based tool for investigating the anxiety-related behavior of rats following manipulation of the central anxiety level. The present paper aims to assess behavioral patterning following pharmacological manipulation of emotional assets in Wistar rats tested in this experimental apparatus. For this purpose, the behavior of three groups of rats injected with saline, diazepam or FG7142 was evaluated using conventional quantitative and multivariate T-pattern analyses. The results demonstrate that quantitative analyses of individual components of the behavior, disjointed from the comprehensive behavioral structure, are of narrow utility in the understanding of the subject’s emotional condition. Among the components of the behavioral repertoire in rodents tested in the Hole-Board, Edge-Sniff and Head-Dip represent the most significant ones to rate anxiety level. They are characterized by a strong bivariate relationship and are also firmly part of the behavioral architecture, as revealed by the T-pattern analysis (TPA), a multivariate technique able to detect significant relationships among behavioral events over time. Edge-Sniff → Head-Dip sequences, in particular, are greatly influenced by the level of anxiety: barely detectable in control animals, they completely disappear in subjects with a reduced level of anxiety and are present in almost 25% of the total of T-patterns detected in subjects whose anxiety level increased.
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18

Yeung, Michelle, Lily Lu, Adam M. Hughes, Dallas Treit i Clayton T. Dickson. "FG7142, yohimbine, and βCCE produce anxiogenic-like effects in the elevated plus-maze but do not affect brainstem activated hippocampal theta". Neuropharmacology 75 (grudzień 2013): 47–52. http://dx.doi.org/10.1016/j.neuropharm.2013.06.027.

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19

Stanford, S. Clare, Stuart C. Taylor i Hilary J. Little. "Chronic desipramine treatment prevents the upregulation of cortical β-receptors caused by a single dose of the benzodiazepine inverse agonist FG7142". European Journal of Pharmacology 139, nr 2 (lipiec 1987): 225–32. http://dx.doi.org/10.1016/0014-2999(87)90255-x.

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Casarrubea, Maurizio, Fabiana Faulisi, Massimiliano Pensabene, Claudio Mendola, Riccardo Dell’Utri, Maurizio Cardaci, Andrea Santangelo i Giuseppe Crescimanno. "Effects of the benzodiazepine inverse agonist FG7142 on the structure of anxiety-related behavior of male Wistar rats tested in hole board". Psychopharmacology 234, nr 3 (12.11.2016): 381–91. http://dx.doi.org/10.1007/s00213-016-4474-8.

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21

Stanford, S. C., H. A. Baldwin i S. E. File. "Effects of a single or repeated administration of the benzodiazepine inverse agonist FG7142 on behaviour and cortical adrenoceptor binding in the rat". Psychopharmacology 98, nr 3 (lipiec 1989): 417–24. http://dx.doi.org/10.1007/bf00451698.

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22

Rüsch, Dirk, i Stuart A. Forman. "Classic Benzodiazepines Modulate the Open–Close Equilibrium in α1β2γ2Lγ-Aminobutyric Acid Type A Receptors". Anesthesiology 102, nr 4 (1.04.2005): 783–92. http://dx.doi.org/10.1097/00000542-200504000-00014.

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Background Classic benzodiazepine agonists induce their clinical effects by binding to a site on gamma-aminobutyric acid type A (GABAA) receptors and enhancing receptor activity. There are conflicting data regarding whether the benzodiazepine site is allosterically coupled to gamma-aminobutyric acid binding versus the channel open-close (gating) equilibrium. The authors tested the hypothesis that benzodiazepine site ligands modulate alpha1beta2gamma2L GABAA receptor gating both in the absence of orthosteric agonists and when the orthosteric sites are occupied. Methods GABAA receptors were recombinantly expressed in Xenopus oocytes and studied using two-microelectrode voltage clamp electrophysiology. To test gating effects in the absence of orthosteric agonist, the authors used spontaneously active GABAA receptors containing a leucine-to-threonine mutation at residue 264 on the alpha1 subunit. To examine effects on gating when orthosteric sites were fully occupied, they activated wild-type receptors with high concentrations of a partial agonist, piperidine-4-sulfonic acid. Results In the absence of orthosteric agonists, the channel activity of alpha1L264Tbeta2gamma2L receptors was increased by diazepam and midazolam and reduced by the inverse benzodiazepine agonist FG7142. Flumazenil displayed very weak agonism and blocked midazolam from further activating mutant channels. In wild-type receptors activated with saturating concentrations of piperidine-4-sulfonic acid, midazolam increased maximal efficacy. Conclusions Independent of orthosteric site occupancy, classic benzodiazepines modulate the gating equilibrium in alpha1beta2gamma2L GABAA receptors and are therefore allosteric coagonists. A Monod-Wyman-Changeux coagonist gating model quantitatively predicts these effects, suggesting that benzodiazepines minimally alter orthosteric ligand binding.
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23

Little, H. J., M. Andreasen i J. D. C. Lambert. "Chronic treatment with a benzodiazepine agonist in vivo increases the actions of the benzodiazepine partial inverse agonist, FG7142, on the hippocampal slice in vitro". Brain Research 573, nr 2 (luty 1992): 243–50. http://dx.doi.org/10.1016/0006-8993(92)90769-6.

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Schultz, John L., Michael Weber, Jayla Allen i Kevin W. Bradley. "Evaluation of Weed Management Programs and Response of FG72 Soybean to HPPD-Inhibiting Herbicides". Weed Technology 29, nr 4 (grudzień 2015): 653–64. http://dx.doi.org/10.1614/wt-d-14-00067.1.

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Field experiments were conducted at two locations in Missouri in 2012 and 2013 to evaluate herbicide programs in 4-hydroxyphenylpyruvate dioxygenase (HPPD)-inhibitor-resistant soybean, referred to as FG72 soybean, and their tolerance to four HPPD-inhibiting herbicides. At the Columbia location, PRE followed by (fb) POST and two-pass POST treatments provided 97% or greater control of all weeds except ivyleaf morningglory. At Moberly in 2012, PRE fb POST treatments provided 95% or greater control and 100% biomass reduction (BR) of glyphosate-resistant (GR) waterhemp, with the exception of isoxaflutole at 0.04 kg ha−1plusS-metolachlor at 0.6 kg ha−1plus metribuzin at 0.2 kg ha−1. In 2013, PRE fb POST treatments provided greater than 89% control and 93% BR. Two-pass POST treatments of isoxaflutole plus glyphosate always provided greater control and BR of GR waterhemp compared with glyphosate fb glyphosate. However, at Columbia, where glyphosate-susceptible weeds were present, there were no differences in control or BR between two-pass POST treatments. In the soybean tolerance experiment, isoxaflutole provided the lowest levels of injury. Applications of tembotrione at the 1× rate resulted in the greatest injury in both years. Topramezone at the 1× rate always provided less injury than tembotrione, but was always similar in BR. The 2× rates increased soybean injury over the 1× rate for the third trifoliate (V3) application, but not for the PRE and first-flower (R1) applications. V3 and R1 applications of isoxaflutole and mesotrione resulted in similar injury, height reduction, and BR to soybean 28 d after application in 2012 and 2013. Overall these results indicate that FG72 soybean could allow the use of HPPD-inhibiting herbicides such as mesotrione PRE along with isoxaflutole PRE and POST to provide an additional herbicide mechanism of action that was not previously available in soybean.
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Xie, Zixin, Shiying Zou, Wentao Xu, Xu Liu, Kunlun Huang i Xiaoyun He. "No subchronic toxicity of multiple herbicide-resistant soybean FG72 in Sprague-Dawley rats by 90-days feeding study". Regulatory Toxicology and Pharmacology 94 (kwiecień 2018): 299–305. http://dx.doi.org/10.1016/j.yrtph.2018.02.004.

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Köppel, René, Thomas Bucher, Anna Frei i Hans-Ulrich Waiblinger. "Droplet digital PCR versus multiplex real-time PCR method for the detection and quantification of DNA from the four transgenic soy traits MON87769, MON87708, MON87705 and FG72, and lectin". European Food Research and Technology 241, nr 4 (18.06.2015): 521–27. http://dx.doi.org/10.1007/s00217-015-2481-3.

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Taiwe, Germain Sotoing, Arielle Larissa Ndieudieu Kouamou, Armelle Rosalie Mbang Ambassa, Joseph Renaud Menanga, Thierry Bang Tchoya i Paul Desire Djomeni Dzeufiet. "Evidence for the involvement of the GABA-ergic pathway in the anticonvulsant activity of the roots bark aqueous extract of Anthocleista djalonensis A. Chev. (Loganiaceae)". Journal of Basic and Clinical Physiology and Pharmacology 28, nr 5 (1.01.2017). http://dx.doi.org/10.1515/jbcpp-2017-0048.

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AbstractBackground:The root bark ofMethods:To investigate the anticonvulsant effects and the possible mechanisms of this plant, an aqueous extract ofResults:This extract significantly protected mice against bicuculline-induced motor seizures. It provided 80% protection against picrotoxin-induced tonic-clonic seizures, and strongly antagonized convulsions induced by pilocarpine. AEAD also protected 100% of mice against pentylenetetrazole-induced seizures. Flumazenil, a central benzodiazepine receptor antagonist and FG7142, a partial inverse agonist in the benzodiazepine site of the GABAConclusions:The effects of
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28

"Soja FG72 Tolérant Deux Herbicides (MST-FG 72-2)". International Food Risk Analysis Journal, 2014, 1. http://dx.doi.org/10.5772/59036.

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"Double Herbicide Tolerant Soybean Event FG72 (MST-FG 72-2)". International Food Risk Analysis Journal, 2014, 1. http://dx.doi.org/10.5772/59035.

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"Scientific Opinion on an application (EFSA‐GMO‐BE‐2011‐98) for the placing on the market of herbicide‐tolerant genetically modified soybean FG72 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 from Bayer CropScience". EFSA Journal 13, nr 7 (lipiec 2015). http://dx.doi.org/10.2903/j.efsa.2015.4167.

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Naegeli, Hanspeter, Andrew Nicholas Birch, Josep Casacuberta, Adinda De Schrijver, Mikołaj Antoni Gralak, Philippe Guerche, Huw Jones i in. "Scientific opinion on application EFSA‐GMO‐NL‐2013‐120 for authorisation of genetically modified soybean FG72 × A5547‐127 for food and feed uses, import and processing submitted in accordance with Regulation (EC) No 1829/2003 by Bayer CropScience LP and M.S. Technologies LLC". EFSA Journal 15, nr 4 (kwiecień 2017). http://dx.doi.org/10.2903/j.efsa.2017.4744.

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