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Artykuły w czasopismach na temat "Etat cellulaire"

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Clément, O. "1305 Imagerie cellulaire : etat actuel et perspectives." Journal de Radiologie 85, no. 9 (2004): 1169. http://dx.doi.org/10.1016/s0221-0363(04)76529-4.

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Li, Long, Mushuang Hu, Long Zheng, et al. "Endothelin Receptor Down-Regulation Mediated Ligand Regulation Mechanisms Protect Against Cellular Hypoxia Injury in Rat Vascular Endothelial Cells." Cellular Physiology and Biochemistry 40, no. 6 (2016): 1443–54. http://dx.doi.org/10.1159/000453196.

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Objective: Investigation of the effect of endothelin receptor A (ETaR)-targeting small interfering RNA (siRNA) on rat vascular endothelial cellular hypoxia injury, as well as its underlying mechanism. Methods: An in vitro rat vascular smooth muscle cells - endothelial cells co-culture model was established and transfected with ETaR siRNA before hypoxia treatment. Cell culture supernatant, cellular protein and RNA were collected and examined at 0.5hrs, 1hrs, 2hrs, 4hrs, 8hrs, 16hrs, 24hrs and 48hrs of hypoxia with 1% oxygen. The time point at which the best silencing effect was achieved was cho
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Swope, V. B., Z. A. Abdel-Malek, D. N. Sauder, and J. J. Nordlund. "A new role for epidermal cell-derived thymocyte activating factor/IL-1 as an antagonist for distinct epidermal cell function." Journal of Immunology 142, no. 6 (1989): 1943–49. http://dx.doi.org/10.4049/jimmunol.142.6.1943.

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Abstract It is known that many immunologic responses to IL-1 are antagonized by the neuropeptide alpha-melanocyte stimulating hormone (alpha-MSH). This led us to investigate the possible reciprocal effects of IL-1 and the functionally related epidermal cytokines, epidermal cell-derived thymocyte activating factor (ETAF) and IL-6, on the melanogenic effect of alpha-MSH on murine Cloudman melanoma cells. When these cells were treated with ETAF in combination with alpha-MSH or its potent analog [Nle4,D-Phe7]-alpha-MSH, the melanotropin induced increase in tyrosinase activity, and thus melanin syn
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Shirato, Ken, Jun Takanari, Junetsu Ogasawara, et al. "Enzyme-Treated Asparagus Extract Attenuates Hydrogen Peroxide-Induced Matrix Metalloproteinase-9 Expression in Murine Skin Fibroblast L929 Cells." Natural Product Communications 11, no. 5 (2016): 1934578X1601100. http://dx.doi.org/10.1177/1934578x1601100532.

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Enzyme-treated asparagus extract (ETAS) exerts a wide variety of beneficial biological actions including facilitating anti-cortisol stress and neurological anti-aging responses. However, the anti-skin aging effects of ETAS remain to be elucidated. Reactive oxygen species (ROS) play pivotal roles in skin aging. Increased ROS levels in fibroblasts in response to ultraviolet irradiation activate c-Jun N-terminal kinase (JNK) and its downstream transcription factor activator protein-1 (AP-1), and the resultant gene expression of matrix metalloproteinase (MMP) isoforms accelerates collagen breakdow
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Agustiningsih, Agustiningsih, Muhammad Rezki Rasyak, Turyadi, Sri Jayanti, and Caecilia Sukowati. "The oncogenic role of hepatitis B virus X gene in hepatocarcinogenesis: recent updates." Exploration of Targeted Anti-tumor Therapy 5, no. 1 (2024): 120–34. http://dx.doi.org/10.37349/etat.2024.00209.

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Hepatocellular carcinoma (HCC) is the most prevalent form of primary liver cancers with high mortality rate. Among its various etiological factors, one of the major risk factors for HCC is a chronic infection of hepatitis B virus (HBV). HBV X protein (HBx) has been identified to play an important role in the HBV-induced HCC pathogenesis since it may interfere with several key regulators of many cellular processes. HBx localization within the cells may be beneficial to HBx multiple functions at different phases of HBV infection and associated hepatocarcinogenesis. HBx as a regulatory protein mo
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Ogasawara, Junetsu, Tomohiro Ito, Koji Wakame та ін. "ETAS, an Enzyme-treated Asparagus Extract, Attenuates Amyloid β-Induced Cellular Disorder in PC 12 Cells". Natural Product Communications 9, № 4 (2014): 1934578X1400900. http://dx.doi.org/10.1177/1934578x1400900435.

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One of the pathological characterizations of Alzheimer's disease (AD) is the deposition of amyloid beta peptide (Aβ) in cerebral cortical cells. The deposition of Aβ in neuronal cells leads to an increase in the production of free radicals that are typified by reactive oxygen species (ROS), thereby inducing cell death. A growing body of evidence now suggests that several plant-derived food ingredients are capable of scavenging ROS in mammalian cells. The purpose of the present study was to investigate whether enzyme-treated asparagus extract (ETAS), which is rich in antioxidants, is one of the
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Bagnato, Anna, Francesca Spinella, and Laura Rosanò. "Emerging role of the endothelin axis in ovarian tumor progression." Endocrine-Related Cancer 12, no. 4 (2005): 761–72. http://dx.doi.org/10.1677/erc.1.01077.

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Ovarian cancer is the leading cause of gynecologic cancer-related deaths. The endothelin (ET) axis, which includes ET-1, ET-2, ET-3, and the ET receptors, ETAR and ETBR, represents a novel target in tumor treatment. ET-1 may directly contribute to tumor growth and indirectly modulate tumor–host interactions in various tumors such as prostatic, ovarian, renal, pulmonary, colorectal, cervical, breast carcinoma, Kaposi’s sarcoma, brain tumors and melanoma. Extensive experimental evidence links ETAR overexpression with tumor progression in ovarian cancer. ETAR engagement can in fact activate multi
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Ward, Carol, James Meehan, Mark E. Gray, et al. "The impact of tumour pH on cancer progression: strategies for clinical intervention." Exploration of Targeted Anti-tumor Therapy 1, no. 2 (2020): 71–100. http://dx.doi.org/10.37349/etat.2020.00005.

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Dysregulation of cellular pH is frequent in solid tumours and provides potential opportunities for therapeutic intervention. The acidic microenvironment within a tumour can promote migration, invasion and metastasis of cancer cells through a variety of mechanisms. Pathways associated with the control of intracellular pH that are under consideration for intervention include carbonic anhydrase IX, the monocarboxylate transporters (MCT, MCT1 and MCT4), the vacuolar-type H+-ATPase proton pump, and the sodium-hydrogen exchanger 1. This review will describe progress in the development of inhibitors
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Zhang, Tie Jun, I. M. Manhrawy, A. A. Abdo, A. A. Abd El-Latif, and R. Rhouma. "Cryptanalysis of Elementary Cellular Automata Based Image Encryption." Advanced Materials Research 981 (July 2014): 372–75. http://dx.doi.org/10.4028/www.scientific.net/amr.981.372.

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An image encryption based on elementary cellular automata was proposed in [Yu Xiao yang etal., International Journal of Security and Its Applications Vol.7, No.5 (2013), pp.397-406.]. In this paper, we analyze the security weaknesses of their algorithm. Based on the given analysis, it is demonstrated that the scheme under study can be broken by various attacks (Chosen Plaintext and Chosen ciphertext attacks).
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Ajayi, Babatunde E., Bola Oboh, Joseph B. Minari, Darren W. Sexton, Satyajit D. Sarker, and Amos A. Fatokun. "Cola rostrata K. Schum. constituents induce cytotoxicity through reactive oxygen species generation and mitochondrial membrane depolarisation." Exploration of Targeted Anti-tumor Therapy 4, no. 6 (2023): 1328–44. http://dx.doi.org/10.37349/etat.2023.00200.

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Aim: While the traditional use of Cola rostrata in treating illnesses and diseases has not been reported, the presence of cytotoxic principles has been reported in phylogenetically and biogeographically related species within the Cola genus. This study, therefore, evaluated the cytotoxic potential of extracts of the plant, and the associated cellular and molecular mechanisms. Methods: Activity-based fractionation of the extracts was carried out and cytotoxicity was assessed in the human cervical cancer cell line, HeLa, and the transformed human lung cell line, MRC5-SV2, using the 3-(4,5-dimeth
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Rozprawy doktorskie na temat "Etat cellulaire"

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Sanchez, Gonzalez Yuriana. "Etude de l’adaptation et de la gestion de l’activité cellulaire dans un bioréacteur biétagé : intensification de la production d’éthanol." Toulouse, INSA, 2008. http://eprint.insa-toulouse.fr/archive/00000247/.

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L’objectif des travaux est de comprendre et quantifier comment gérer l’activité cellulaire de la levure Saccharomyces cerevisiae afin d’intensifier les productions microbiennes (spécifiquement la production d’éthanol biocarburant) dans un Bioréacteur Biétagé avec Recyclage cellulaire (BBRC) en mode continu. En effet, les performances globales du procédé sont directement affectées par le maintien de l’activité cellulaire et notre étude cible la quantification du comportement de la levure en fonction de son état physiologique et lorsqu’elle est soumise à des changements d’environnement caractéri
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Tournebize, Juliana. "Synthèse de nanoparticules d'or fonctionnalisées par l'acide dihydrolipoïque : caractérisation, étude de stabilité et impact sur l'homéostasie redox cellulaire." Thesis, Université de Lorraine, 2012. http://www.theses.fr/2012LORR0030/document.

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L'objectif de notre travail consiste en la conception de nanoparticules d'or (AuNP) monodisperses, et stables ; puis en l'évaluation de l'effet des propriétés de surface de AuNP sur leur internalisation et leur toxicité dans une lignée cellulaire (macrophages alvéolaires de rat-NR8383). Nous avons synthétisé des NP d'or soit stabilisées par les ions citrate (Au-citrate) soit fonctionnalisées par l'acide dihydrolipoïque (DHLA) (NP Au@DHLA). Nous avons montré que la densité de couverture est un paramètre crucial pour améliorer la stabilité colloïdale des AuNP dans des conditions physiologiques.
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Molle, Boris. "Etude des propriétés dynamiques de structures cellulaires formées dans un système eau/huile/surfactant/alcool." Université Joseph Fourier (Grenoble), 2000. http://www.theses.fr/2000GRE10249.

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Dans cette these sont etudiees les proprietes dynamiques d'un systeme eau/toluene/sds/butanol qui forme spontanement des structures de type cellulaire a l'echelle nanoscopique, ou l'huile est confinee dans des cellules polyedriques separees par un film d'eau. A temperature ambiante le systeme est liquide et l'arrangement des cellules est macroscopiquement desordonne. Lorsque la temperature augmente le systeme devient viscoelastique et forme des structures cellulaires cristallines cubiques. La combinaison de differentes techniques experimentales a permis d'explorer la dynamique a differentes ec
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Leclercq, Pascale. "Etat infectieux et métabolisme des hydrates de carbone : études in vitro sur hépatocytes isolés et in vivo chez des patients infectés par le VIH." Université Joseph Fourier (Grenoble ; 1971-2015), 1997. http://www.theses.fr/1997GRE10122.

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Le sepsis induit une inhibition de la neoglucogenese (ngg). Modele experimental : sepsis de gravite moderee chez des rats traites par endotoxine avec preparation d'hepatocytes isoles et technique de perfusion. Localisation du niveau et des mecanismes de l'inhibition. Inhibition au niveau du cycle pyruvatephosphoenolpyruvate sans modification de la pyruvate kinase (role de la pepck). Pas d'alteration du cycle des fructoses par le sepsis ; possible inhibition du cycle des glucoses (inhibition de la glucose-6-phosphatase). Etude de la ngg a partir du glycerol (independante de la pepck et fonction
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Meyer, Swann. "Molecular characterization of aggressive cell states in pediatric gliomas and sarcomas." Electronic Thesis or Diss., Lyon 1, 2024. http://www.theses.fr/2024LYO10364.

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Bien que considérés comme des maladies rares, les cancers pédiatriques sont la 2e cause de mortalité chez les enfants de moins de 14 ans dans les pays occidentaux. Des progrès considérables ont été réalisés dans les années 1970, avec une survie globale de 70% atteinte en une vingtaine d’années. Néanmoins, certains sous-groupes sont toujours associés à un pronostic sévère, et la question des séquelles dues aux traitements demeure. Ces défis proviennent notamment du fait que la majorité des traitements des cancers pédiatriques ont initialement été développés pour des cancers de l’adulte, alors q
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Joux, Fabien. "Dynamique des etats physiologiques des populations bacteriennes en eau de mer : approche cellulaire en conditions de survie." Paris 6, 1997. http://www.theses.fr/1997PA066396.

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Les objectifs de ce travail ont ete d'analyser l'heterogeneite et la dynamique des etats physiologiques au sein (1) de populations bacteriennes soumises a differentes conditions de stress, en choisissant un modele de bacterie allochtone au milieu marin (salmonella typhimurium) et differentes bacteries marines (deleya aquamarina, alteromonas haloplanktis, vibrio fischeri, vibrio sp. ), et (2) des communautes naturelles. Pour repondre a ces objectifs, differents protocoles permettant l'analyse cellulaire de fonctions physiologiques et de l'adn ont ete definis. Ces analyses ont ete effectuees par
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Lebrun, Marie-Monique. "Instabilites cellulaires en solidification directionnelle : experiences en couches minces." Paris 7, 1987. http://www.theses.fr/1987PA077013.

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Etude de l'apparition d'instabilites morphologiques a l'interface liquide-solide dans des echantillons minces d'un corps transparent (tetrabromomethane avec quelques pour mille d'impuretes). Observation en direct a l'aide d'un microscope optique d'une camera video, ce qui donne acces a la dynamique de solidification
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Amillastre, Emilie. "Amélioration de la robustesse de souches de levures aux stress technologiques par une stratégie de génie microbiologique : Application à la production industrielle de bio-éthanol à partir de matières premières agricoles." Thesis, Toulouse, INSA, 2012. http://www.theses.fr/2012ISAT0058/document.

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Sous contraintes industrielles, les micro-organismes sont soumis à différents stress technologiques, liés à leur culture en réacteur de grande taille, altérant leur viabilité et les performances des procédés. Les fluctuations des paramètres physico-chimiques (température, pH, …) sont responsables de cette baisse d’efficacité de la fermentation. Afin de contribuer à l’intensification des performances des procédés de production de bio-éthanol, ce projet de thèse propose d’améliorer la robustesse d’une souche industrielle de Saccharomyces cerevisiae productrice d’alcool vis-à-vis d’un stress envi
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Guergouri, Kamel. "Etude des defauts cristallins et des proprietes physiques associees dans cdte et ses alliages avec znte, mnte." Paris 6, 1987. http://www.theses.fr/1987PA066412.

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Etude de l'amelioration de cdte dans le cadre de la recherche de semiconducteurs de bonne qualite cristalline. Le premier parametre necessaire a cette amelioration et celui de la substitution de cd par zn (impurete isoelectronique et permet la reduction de la densite de dislocations d'un facteur 10. Proposition d'un modele de durcissement d'alliage pour expliquer ce phenomene. Le 2eme parametre concerne la recherche des conditions de croissance optimales
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Nicolay, N. H. "The role of DNA polymerase eta in determining cellular responses to chemo-radiation treatment." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:73cef89c-319d-4a14-a3a6-93e8b8dd186a.

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DNA polymerase η (pol η), a crucial component of the cellular translesion synthesis pathway, allows cells to bypass and thereby temporarily tolerate DNA damage. Inherited deficiency of pol η, as reported in the variant form of xeroderma pigmentosum, predisposes to UV light-induced skin cancers. To date, pol η is the only DNA polymerase shown to exhibit a causal link to the formation of cancers in humans. However, the role of pol η in the cellular response to forms of DNA damage other than UV-induced lesions is largely unknown. In the first part of this thesis, it is shown that cells deficient
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Książki na temat "Etat cellulaire"

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Abellan, Stephanie, and Anais Toutin. L'oracle d'Ankaa : le guide: Libération des etats d'âme & Nettoyage de la mémoire cellulaire. Independently published, 2019.

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Abellan, Stephanie, and Anais Toutin. L'oracle d'Ankaa : le guide: Libération des etats d'âme & Nettoyage de la mémoire cellulaire. Independently published, 2019.

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Części książek na temat "Etat cellulaire"

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Daniel, Juliet, Gerald Weeks, and George B. Spiegelman. "Dictyostelium ras genes." In Guidebook to the Sinall GTPases. Oxford University PressOxford, 1995. http://dx.doi.org/10.1093/oso/9780198599456.003.0029.

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Abstract Five ras genes (rasB, rasC, rasD, rasG and rasS) and one rap gene (rap1) have been isolated and characterized in the cellular slime mold Dictyostelium discoideum (Daniel etal. 1993,1994; Reymond etal. 1984; Robbins eta/. 1989,1990). These ras subfamily genes encode 21-22 kDa GTP-binding proteins that have 52-68% amino acid identity with the human H-Ras protein (Table 1). These genes all appear to be present in a single copy since each of their cognate cDNAs hybridizes to a single, unique genomic fragment under high stringency conditions.
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Settleman, Jeffrey. "pl90." In Guidebook to the Sinall GTPases. Oxford University PressOxford, 1995. http://dx.doi.org/10.1093/oso/9780198599456.003.0075.

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Abstract The p190 protein was first identified in 1990 as a phosphotyrosine-containing protein that co-immunoprecipitates with p120 Ras-GAP in growth factor-stimulated and tyrosine kinase-transformed cells (Ellis etal. 1990; Moran etal. 1991). Since that time, p190 has not been reported to associate stably with any other proteins or cellular components. p190 does, however, make contact with members of the Rho family of small GTPases, and probably binds directly to guanine nucleotides, as is described in the ‘functional studies’ section.
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Sandblom, John, Sheila Galt, Dan Roos,, and Yngve Hamnerius. "Possible resonance effects of ELF magnetic fields on ion channels." In Interaction Mechanisms of Low-Level Electromagnetic Fields in Living Systems. Oxford University PressOxford, 1992. http://dx.doi.org/10.1093/oso/9780198577591.003.0010.

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Abstract Considerable evidence has accumulated during recent years that ELF (extremely low-frequency) magnetic fields can interact with living tissues at the cellular level (Adey and Bawin 1982; Blackman etal. 1985a, b; McLeod et al. 1987; Smith et al. 1987). Existing data seem consistently to indicate the occurrence of regions of maximal absorption of energy, i.e. resonance effects, with respect to amplitude and frequencies of the magnetic fields. Examples of such systems are the calcium efflux from brain tissue (Adey and Bawin 1982; Blackman et al. 1985a, b) and the motility of diatoms (McLe
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Tropschug, M. "Neurospora crassa cydophilins." In Guidebook to Molecular Chaperones and Protein-Folding Catalysts. Oxford University PressOxford, 1997. http://dx.doi.org/10.1093/oso/9780198599494.003.00148.

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Abstract Fungi like Neurospora crassa or Saccharomyces cerevisiae are ideal organisms to study the cellular roles of the different peptidyl-prolyl cis-trans isomerases (PPIases) and the molecular mechanisms of action of immunosuppressants like CsA, FK506 or rapamycin (reviewed by Kunz and Hall, 1993). These drugs were originally isolated as antifungal compounds. Three families of PPIases have been described. Two of these, the cyclophilins (Cyps) and FKBPs, have been known for some time (see reviews by Schreiber, 1992; Schmid, 1993; Fischer, 1994; Galat and Metcalfe, 1995; see also the overview
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"DNA translesion synthesis in cellular response to oxidative stress and ionizing radiation." In Book of Abstracts - RAD 2025 Conference. RAD Centre, Niš, Serbia, 2025. https://doi.org/10.21175/rad.abstr.book.2025.4.6.

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Oxidative stress and ionizing radiation is a source of DNA damage causing replication stress, mutagenesis and cell death. The DNA damage response (DDR) includes evolutionarily conserved mechanisms of DNA repair (such as base excision repair and homologues recombination) and DNA translesion synthesis. We analyzed the mutagenic and cytotoxic potential of 8-oxoguanine (8-oxoG) and 8- oxoadenine (8-oxoA) – two major DNA lesions caused by reactive oxygen species. We carried out DNA polymerase reactions with five human DNA polymerases involved in base excision repair (Pol beta, Pol lambda), DNA tran
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Celio, Marco R. "Calreticulin." In Guidebook to the Calcium-binding Proteins. Oxford University PressOxford, 1996. http://dx.doi.org/10.1093/oso/9780198599517.003.0028.

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Abstract Calreticulin is a ubiquitous and highly conserved Ca2+-bindinglstorage protein associated with endo(sarco)plasmic reticulum membranes. Calreticulin is a multifunctional protein implicated to play a role in a variety of cellular functions ranging from Ca2+homeostasis to the control of gene expression. Rabbit calreticulin has a calculated molecular weight of 46, 567 (for recent reviews on the structure, function, amino acid sequence and localization of calreticulin see Michalak et al. 1992; Sontheimer et al. 1993; Burns et al. 1994; Nash et al. 1994 and references within). The protein m
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Kaplan, O., and J. S. Cohen. "Nuclear Magnetic Resonance Spectroscopy Studies of Cancer Cell Metabolism." In Biological NMR Spectroscopy. Oxford University Press, 1997. http://dx.doi.org/10.1093/oso/9780195094688.003.0030.

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Nuclear magnetic resonance spectroscopy (NMR) is a powerful technique that provides information on biochemical status and physiological processes both in-vitro and in-vivo. The metabolism of intact cells and tissues can be studied in a continuous manner, and thus, NMR is a unique non-invasive research tool enabling detection of the metabolic changes as they occur (Cohen et al., 1983; Morris, 1988; Daly and Cohen, 1989). The first NMR study of cellular metabolism was done some 20 years ago, when Moon and Richards reported on the diphosphoglyceric acid (DPG) and pH shifts in erythrocytes (Moon,
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Streszczenia konferencji na temat "Etat cellulaire"

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Zhou, Shuqiu, and Junxian Meng. "An Improved Algorithm of the Cellular Automata on the Evacuation Simulation." In 2008 International Workshop on Geoscience and Remote Sensing (ETT and GRS). IEEE, 2008. http://dx.doi.org/10.1109/ettandgrs.2008.240.

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Milligan, W. W., P. G. Sanders, C. L. White, J. P. Shingledecker, and D. F. Purdy. "Design, Creep Performance and Deformation Behavior of an Eta-Phase Strengthened Nickel-Base Alloy for A-USC Power Plant Applications." In AM-EPRI 2016, edited by J. Parker, J. Shingledecker, and J. Siefert. ASM International, 2016. http://dx.doi.org/10.31399/asm.cp.am-epri-2016p0202.

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Abstract By utilizing computational thermodynamics in a Design of Experiments approach, it was possible to design and manufacture nickel-base superalloys that are strengthened by the eta phase (Ni3Ti), and that contain no gamma prime (Ni3Al,Ti). The compositions are similar to NIMONIC 263, and should be cost-effective, and have more stable microstructures. By varying the aging temperature, the precipitates took on either cellular or Widmanstätten morphologies. The Widmanstätten-based microstructure is thermally stable at high temperatures, and was found to have superior ductility, so developme
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Raporty organizacyjne na temat "Etat cellulaire"

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Meidan, Rina, and Joy Pate. Roles of Endothelin 1 and Tumor Necrosis Factor-A in Determining Responsiveness of the Bovine Corpus Luteum to Prostaglandin F2a. United States Department of Agriculture, 2004. http://dx.doi.org/10.32747/2004.7695854.bard.

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The corpus luteum (CL) is a transient endocrine gland that has a vital role in the regulation of the estrous cycle, fertility and the maintenance of pregnancy. In the absence of appropriate support, such as occurs during maternal recognition of pregnancy, the CL will regress. Prostaglandin F2a (PGF) was first suggested as the physiological luteolysin in ruminants several decades ago. Yet, the cellular mechanisms by which PGF causes luteal regression remain poorly defined. In recent years it became evident that the process of luteal regression requires a close cooperation between steroidogenic,
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