Artykuły w czasopismach na temat „Epilepsy”
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Budiman, Marshen, Praevilia M. Salendu i Johnny L. Rompis. "Pengaruh Riwayat Kejang Demam terhadap Kejadian Epilepsi pada Anak". e-CliniC 11, nr 1 (10.10.2022): 19. http://dx.doi.org/10.35790/ecl.v11i1.37740.
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Abstract: Epilepsy could cause various kinds of problems including learning difficulties, growth and development disorders, and poor quality of life of children in the future. There are several risk factors of febrile seizures that coud affect the occurrence of epilepsy inter alia abnormalities of the nervous system or there is a clear development of nervous system abnormalities before the seizure, complex febrile seizures, history of epilepsy in parents or siblings, as well as simple febrile seizures repeating four or more episodes in one year. Each of these risk factors increases the likeli-hood of epilepsy, and the combination of these risk factors increases the incidence of epilepsy. This study aimed to determine the effect of a history of febrile seizures on the incidence of epilepsy in children. This was a literature review study using three databases namely Pubmed, ClinicalKey, and Google Scholar. The keywords used were febrile seizure AND epilepsy AND children. Selection with inclusion and exclusion criteria obtained 10 literatures. The results showed that from 10 literatures reviewed, history of febrile seizures was the most common risk factor that influenced the developing of epilepsy in later life. In conclusion, history of febrile seizures is the most common risk factor for developing epilepsy in children later in life. The percentage of children with history of febrile seizure that develop to epilepsy is 3.3% - 73.8%.Keywords: febrile seizures; epilepsy; children Abstrak: Epilepsi dapat menyebabkan berbagai macam permasalahan berupa kesulitan dalam belajar, gangguan pertumbuhan dan perkembangan, serta kualitas hidup yang kurang pada anak di masa depan. Terdapat beberapa faktor risiko kejang demam yang berperan terhadap terjadinya epilepsi, di antaranya: kelainan pada sistem saraf atau adanya perkembangan kelainan yang jelas sebelum kejang, kejang demam kompleks, riwayat epilepsi pada orang tua atau suadara kandung, dan kejang demam sederhana yang berulang empat episode atau lebih dalam satu tahun. Masing-masing faktor risiko tersebut meningkatkan kemungkinan kejadian epilepsi dan kombinasi faktor risiko tersebut akan meningkatkan kejadian epilepsi. Penelitian ini bertujuan untuk mengetahui pengaruh riwayat kejang demam terhadap kejadian epilepsi pada anak. Penelitian ini berbentuk literature review, menggunakan tiga database yaitu Pubmed, ClinicalKey, dan Google Scholar. Kata kunci yang digunakan yaitu febrile seizure AND epilepsy AND children. Hasil seleksi dengan kriteria inklusi dan eksklusi mendapatkan 10 literatur. Hasil penelitian menunjukkan bahwa dari sepuluh jurnal yang di-review, didapatkan riwayat kejang demam menjadi salah satu faktor risiko yang memiliki pengaruh untuk berkembang menjadi epilepsi di kemudian hari. Simpulan penelitian ini ialah riwayat kejang demam merupakan faktor risiko terbanyak untuk berkembang menjadi epilepsi pada anak di kemudian hari. Persentase anak dengan riwayat kejang demam yang berkembang menjadi epilepsi berkisar antara 3,3% - 73,8%.Kata kunci: kejang demam; epilepsi; anak
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Tri Utami, Melinda, Refani Adisti Rahmadini, Adelia Putri, Damayanti, Sri Ana, Rian Dzikrianto i Yulia Hermawati. "REVIEW ARTIKEL : PENGGUNAAN OBAT ANTI EPILEPSI DI RUMAH SAKIT". Medimuh : Jurnal Kesehatan Muhammadiyah 4, nr 2 (28.12.2023): 113–18. http://dx.doi.org/10.37874/mh.v4i2.632.
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ABSTRAK
Epilepsi adalah gangguan pada sistem saraf pusat akibat pola aktivitas listrik yang berlebihan di otak (Rahmat, 2021). Epilepsi memerlukan pengobatan yang lama (Dewi, 2020). Kepatuhan minum obat akan mempengaruhi hasil pengobatan. Hal ini menyebabkan penderitanya mengalami kejang secara berulang pada sebagian atau seluruh tubuh. Tujuan penelitian ini untuk mengetahui penggunaan obat antiepilepsi di Rumah Sakit dan untuk mengetahui beberapaorang yang menderita epilepsi di berbagai kota di Indonesia. Metode penelitian yang digunakan dalam artikel ini dengan mengumpulan jumlah penelitian sebanyak 11 jurnal dari situs “Google Scholar” dengan kata kunci anti epilepsi, epilepsi, pengobatan anti epilepsi, penggunaan obat anti epilepsi.
Kata kunci : anti epilepsi, pengobatan antiepilepsi, epilepsi, penggunaan obat anti epilepsi.
ABSTRACT
Epilepsy is the use of disordes of the central nervous system due to excessive electrical activity patterns in the brain. Epilepsy requires prolonged treatment. Medication adherence will affect the outcome of treatment. This causes the sufferer to experience repeated seizures in parts or the whole body. The purpose of this study was to dertemine the use of anti-epileptic drugs in hospitals and to find out how many people suffer from epilepsy in various cities in Indonesia. The research method used in this article by collecting 11 research journals from the “Google Scholar” site with the keywords antidpilepticm,epilepsy, anti-epileptic medication, use of antiepileptic drugs.
Keywords: anti epilepsy, anti epileptic medication, epilepsy, use of anti-epileptic drugs
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Budiman, Marshen, Praevilia M. Salendu i Johnny L. Rompis. "Pengaruh Riwayat Kejang Demam terhadap Kejadian Epilepsi pada Anak". e-CliniC 11, nr 1 (10.10.2022): 19–26. http://dx.doi.org/10.35790/ecl.v11i1.44268.
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Abstract: Epilepsy could cause various kinds of problems including learning difficulties, growth and development disorders, and poor quality of life of children in the future. There are several risk factors of febrile seizures that coud affect the occurrence of epilepsy inter alia abnormalities of the nervous system or there is a clear development of nervous system abnormalities before the seizure, complex febrile seizures, history of epilepsy in parents or siblings, as well as simple febrile seizures repeating four or more episodes in one year. Each of these risk factors increases the likeli-hood of epilepsy, and the combination of these risk factors increases the incidence of epilepsy. This study aimed to determine the effect of a history of febrile seizures on the incidence of epilepsy in children. This was a literature review study using three databases namely Pubmed, ClinicalKey, and Google Scholar. The keywords used were febrile seizure AND epilepsy AND children. Selection with inclusion and exclusion criteria obtained 10 literatures. The results showed that from 10 literatures reviewed, history of febrile seizures was the most common risk factor that influenced the developing of epilepsy in later life. In conclusion, history of febrile seizures is the most common risk factor for developing epilepsy in children later in life. The percentage of children with history of febrile seizure that develop to epilepsy is 3.3% - 73.8%.
Keywords: febrile seizures; epilepsy; children
Abstrak: Epilepsi dapat menyebabkan berbagai macam permasalahan berupa kesulitan dalam belajar, gangguan pertumbuhan dan perkembangan, serta kualitas hidup yang kurang pada anak di masa depan. Terdapat beberapa faktor risiko kejang demam yang berperan terhadap terjadinya epilepsi, di antaranya: kelainan pada sistem saraf atau adanya perkembangan kelainan yang jelas sebelum kejang, kejang demam kompleks, riwayat epilepsi pada orang tua atau suadara kandung, dan kejang demam sederhana yang berulang empat episode atau lebih dalam satu tahun. Masing-masing faktor risiko tersebut meningkatkan kemungkinan kejadian epilepsi dan kombinasi faktor risiko tersebut akan meningkatkan kejadian epilepsi. Penelitian ini bertujuan untuk mengetahui pengaruh riwayat kejang demam terhadap kejadian epilepsi pada anak. Penelitian ini berbentuk literature review, menggunakan tiga database yaitu Pubmed, ClinicalKey, dan Google Scholar. Kata kunci yang digunakan yaitu febrile seizure AND epilepsy AND children. Hasil seleksi dengan kriteria inklusi dan eksklusi mendapatkan 10 literatur. Hasil penelitian menunjukkan bahwa dari sepuluh jurnal yang di-review, didapatkan riwayat kejang demam menjadi salah satu faktor risiko yang memiliki pengaruh untuk berkembang menjadi epilepsi di kemudian hari. Simpulan penelitian ini ialah riwayat kejang demam merupakan faktor risiko terbanyak untuk berkembang menjadi epilepsi pada anak di kemudian hari. Persentase anak dengan riwayat kejang demam yang berkembang menjadi epilepsi berkisar antara 3,3% - 73,8%.
Kata kunci: kejang demam; epilepsi; anak
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Kurnia, Bonar, Edward Nangoy i Jimmy Posangi. "Diet Ketogenik untuk Penyakit Epilepsi Resisten Obat". Jurnal Biomedik:JBM 13, nr 3 (10.04.2021): 282. http://dx.doi.org/10.35790/jbm.13.3.2021.31946.
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Abstract: Epilepsy is estimated to affect 70 people worldwide. Anti-epileptic drugs (AED) as the main therapy for epilepsy can treat epilepsy in 70% of patients but 20-30% of patients experience Drug-Resistant Epilepsy (DRE). One therapy that can be given to patients who are not responsive to AED is ketogenic diet, a diet high in fat, low in carbohydrates and sufficient protein, which can help control seizures. The mechanism of action is still not known, but it may relate to AED. This study aims to determine the role or effect of ketogenic diet for DRE. This research is in the form of a literature review. In this study, the ketogenic diet was found to be effective in treating DRE especially in reducing seizure frequency. Ketogenic diet is particularly effective in treating focal seizures and West syndrome, and the correlation between ketogenic diet and AED can be found in a theory of the mechanism of action of the ketogenic diet with the mechanism of action of AED which is the actual therapy of this epilepsy. Ketogenic diet is effective as an alternative therapy for DRE in infants to adults. What needs to be considered is the type of ketogenic diet used must be suitable for the patient in order to achieve the best adherence, tolerability and effectiveness. Classification of the patient's epilepsy such as the type of seizure or the etiology of the epilepsy may also be a factor in starting a ketogenic diet therapy.Keywords: Epilepsy, Refractory Epilepsy, Drug Resistant Epilepsy, Ketogenic Diet Abstrak: Epilepsi diperkirakan diderita oleh 70 orang di seluruh dunia. Obat anti epilepsi (OAE) sebagai terapi utama untuk epilepsi dapat menangani epilepsi pada 70% penderita namun 20-30% pasien mengalami Epilepsi Resisten Obat. Terapi yang dapat diberikan untuk pasien yang tidak responsif terhadap pemberian OAE adalah diet ketogenik, diet tinggi lemak, rendah karbohidrat dan cukup protein yang dapat membantu mengontrol bangkitan. Mekanisme kerja diet ketogenik masih belum diketahui namun kemungkinan ada kaitannya dengan OAE. Penelitian ini bertujuan untuk mengetahui peran atau efek diet ketogenik untuk penyakit epilepsi resisten obat. Penelitian ini berbentuk literature review. Dalam penelitian ini, diet ketogenik ditemukan efektif untuk menangani epilepsi resisten obat khususnya dalam menurunkan frekuensi bangkitan. Diet ketogenik secara khusus efektif dalam menangani bangkitan fokal dan sindrom west, dan korelasi antara diet ketogenik dengan OAE dapat ditemukan dalam teori mekanisme kerja diet ketogenik dengan mekanisme kerja OAE yang merupakan terapi sebenarnya epilepsi ini. Diet ketogenik efektif sebagai terapi alternatif untuk epilepsi resisten obat baik untuk pasien bayi hingga dewasa. Adapun yang perlu diperhatikan adalah jenis diet ketogenik yang digunakan harus sesuai dengan pasien guna mencapai ketaatan, tolerabilitas dan efektivitas yang terbaik. Klasifikasi epilepsi pasien seperti tipe bangkitan atau etiologi penyebab epilepsi dapat juga menjadi faktor pertimbangan untuk memulai terapi diet ketogenik.Kata Kunci: Epilepsi, Epilepsi Refrakter, Epilepsi Resisten Obat, Diet Ketogenik
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Sari, Putu Ratih Padmarini Gantari, Dewi Sutriani Mahalini, I. Nyoman Budi Hartawan i Dyah Kanya Wati. "Tingkat kualitas hidup pasien anak epilepsi dengan QOLCE-16". Intisari Sains Medis 14, nr 3 (30.12.2023): 1249–53. http://dx.doi.org/10.15562/ism.v14i3.1908.
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Background: Epilepsy is defined clinically as unprovoked seizures lasting more than 24 hours. In Indonesia there are more than 700.000 to 1.400.000 cases of epilepsy with an increase of around 70,000 new cases every year. In addition, it is estimated that 40-50% occur in children. The level of quality of life of people with epilepsy is worth paying attention to because it is an indicator of the success of treating epilepsy sufferers. This research was conducted to determine the quality of life of pediatric epilepsy patients using an instrument, namely the quality of life in childhood epilepsy questionnaire-16 (QOLCE-16). Method: The research was conducted by conducting interviews with the patient's parents. Data presentation is carried out descriptively. Sample determination was carried out using the sample size formula for nominal data, with a minimum sample of 92 people. Results: Total of 93 samples that met the inclusion criteria, it was found that the majority of people with epilepsy were aged 6-11 years (44.09%), male (63.44%), with comorbidities (53.76%) , suffered from epilepsy for more than 3 years (62.37%). Apart from that, it was also found that the type of epilepsy most commonly suffered was generalized epilepsy (41.94%), the last education of the patient's parents was junior high school (48.39%) and the parents' income was below IDR 1,500,000-, (41, 94%). Conclusion: After conducting interviews with QOLCE-16, it was found that more samples had a low quality of life (61.29%). Latar Belakang: Epilepsi merupakan didefinisikan secara klinis sebagai kejadian kejang yang tidak terprovokasi yang menyerang lebih dari 24 jam. Di Indonesia terdapat lebih dari 700.000 sampai dengan 1.400.000 kasus epilepsi dengan pertambahan sekitar 70.000 kasus baru setiap tahunnya. Selain itu, diperkirakan 40-50% terjadi pada anak-anak. Tingkat kualitas hidup penyandang epilepsi patut diperhatikan karena merupakan salah satu indikator keberhasilan perawatan penderita epilepsy. Penelitian ini dilakukan untuk mengetahui kualitas hidup pasien anak epilepsi menggunakan sebuah instrument yaitu quality of life in childhood epilepsy questionnaire-16 (QOLCE-16). Metode: Penelitian dilakukan dengan cara melakukan wawancara dengan orang tua pasien. Penyajian data dilakukan secara deskriptif. Penentuan sampel dilakukan dengan rumus besar sampel untuk data nominal, dengan sampel minimal adalah 92 orang. Hasil: Dari 93 sampel yang memenuhi kriteria inklusi ditemukan bahwa terdapat paling banyak penderita epilepsi berada di usia 6-11 tahun (44,09%), berjenis kelamin laki-laki (63,44%), dengan komorbiditas (53,76%), menderita epilepsi selama lebih dari 3 tahun (62,37%). Selain itu, didapatkan juga bahwa tipe epilepsi yang paling banyak diderita adalah epilepsi umum (41,94%), pendidikan terakhir orang tua pasien adalah SMP (48,39%) serta penghasilan orang tua di bawah Rp 1.500.000-, (41,94%). Simpulan: Setelah dilakukan wawancara dengan QOLCE-16 didapatkan bahwa lebih banyak sampel yang memiliki kualitas hidup rendah (61,29%).
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Sert, Havva, Serap Çetinkaya, Ahmet Seven i Meryem Pelin. "Knowledge levels of senıor nursing students about epilepsyHemşirelik son sınıf öğrencilerinin epilepsi hakkındaki bilgi düzeyleri". Journal of Human Sciences 14, nr 2 (30.05.2017): 1966. http://dx.doi.org/10.14687/jhs.v14i2.4532.
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Aim: This study was conducted to determine knowledge levels and the factors affecting of senior nursing students about epilepsy.Method: The study was conducted descriptively and cross-sectional between 17-27 January 2017 with 168 nursing senior students who agreed to participate in the study. The data was collected on social media with questionnaire which was composed of the literature review by the researchers. 15 of the questions were about socio-demographic characteristics and 20 of questions were about epilepsy. Analysing of data were carried out in a computer program by using percentage, Mann-Whitney U and Kruskal Wallis-H test.Results: It was determined that mean score of the students' knowledge level about epilepsy is 81,10±7,27. There was a statistically significant relationship between where they got the information about epilepsy, care a patient previously had a seizure and mean scores of epilepsy knowledge level (p<0,05). It was determined that students ,who got information about epilepsy from the health personnel and those who care a patient previously had a seizure, had high mean scores.Conclusion: In the study, ıt was determined that nursing senior students’ knowledge level about the epilepsy is high; where they got the information about epilepsy, care a patient previously had a seizure affects epilepsy knowledge.Extended English abstract is in the end of PDF (TURKISH) file. ÖzetAmaç: Bu çalışma, hemşirelik son sınıf öğrencilerinin epilepsi hakkındaki bilgi düzeylerini ve etkileyen faktörleri belirlemek amacıyla yapıldı.Gereç ve Yöntem: Çalışma, 17-27 Ocak 2017 tarihleri arasında çalışmaya katılmayı kabul eden 168 hemşirelik son sınıf öğrencisiyle tanımlayıcı ve kesitsel olarak yapıldı. Çalışmanın verileri sosyal medya aracılığı ile toplandı. Verilerin toplanmasında araştırmacılar tarafından literatür taranarak oluşturulan, 15’i sosyo-demogrofik özellikleri, 20’si epilepsi hakkında bilgi durumlarını ölçmeye yönelik sorudan oluşan soru formu kullanıldı. Veriler; bilgisayar ortamında, yüzdelik, Mann-Whitney U ve Kruskal Wallis-H testleri kullanılarak değerlendirildi.Bulgular: Öğrencilerin epilepsi bilgi düzeyleri toplam puan ortalamalarının 81,10±7,27 olduğu belirlendi. Öğrencilerin epilepsi hakkında bilgiyi nereden aldığı ve daha önce nöbet geçiren hastaya bakma durumları ile epilepsi bilgi düzeyi toplam puan ortalamaları arasında istatiksel olarak anlamlı ilişki olduğu saptandı (p<0,05). Sonuç: Çalışmada hemşirelik son sınıf öğrencilerinin epilepsi hakkındaki bilgi düzeylerinin yüksek olduğu; epilepsi hakkında bilgiyi nereden aldığı ve daha önce nöbet geçiren hastaya bakım vermenin epilepsi bilgi durumunu etkilediği belirlendi.
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Ramadhan, Muhammad Fitra, Prastiya Indra Gunawa i Muhammad Arifin Parenrengi. "Faktor-Faktor Risiko Pasien Epilepsi Intraktabel pada Anak". Malahayati Nursing Journal 4, nr 12 (1.12.2022): 3321–34. http://dx.doi.org/10.33024/mnj.v4i12.7518.
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ABSTRACT Approximately 10.5 million children are diagnosed with active epilepsy worldwide, accounting for 25% of the world's population with epilepsy. Among 1 in 3 people who are diagnosed with epilepsy will develop intractable epilepsy, this means that regular and adequate treatment for 18 months does not show a decrease in the frequency and duration of seizures or has taken 2 anti-epileptic drugs but has not yet had an effect. The aim of this study was to analyze the risk factors that can cause intractable epilepsy in pediatric patients. This study used a retrospective observational research design with a systematic review approach, where all variable data were collected from previous studies. The collection of research data is collected from previous research data in the form of research journals collected from the scholar.google.co.id, NCBI, and science direct databases. The article search method uses the characteristics of PICO (Population, Intervention, Comparison, Outcome), then the data in the form of articles that have been collected are managed using the Preffered Reporting Items for Systematic Review and Meta-Analysis (PRISMA) method. Based on 9 articles that have been reviewed, it is found that there are no studies that include age as a risk factor for intractable epilepsy. Odds ratios for each risk factor varied, but the most studied risk factors in the study included in this study were developmental disorders (8/9), MRI / CT Scan (6/9), and status epilepticus (5/9). 9). From the results of this systematic review, the factors that most influence intractable epilepsy in children are developmental disorders with the highest odds ratio of 37.1 obtained in the study of Wirell et al. Gender factors, duration of seizure, family history of epilepsy, and history of febrile seizures did not significantly influence intactable epilepsy. In conclusion, this study found that the factors that most influence intractable epilepsy in children are developmental disorders and status epilepticus. Keywords: Risk Factors, Intractable Epilepsy, Children ABSTRAK Di seluruh dunia, sekitar 10,5 juta anak didiagnosis dengan epilepsi aktif, sebesar 25% dari populasi dunia dengan pengidap epilepsi. Diantara 1 dari 3 orang yang terdiagnosis epilepsi akan dapat berkembang menjadi epilepsi intraktabel, hal ini dapat diartikan bahwa pengobatan yang dilakukan selama 18 bulan secara teratur dan adekuat tidak menunjukkan penurunan frekuensi dan durasi kejang atau sudah mengonsumsi 2 obat anti epilepsi namun belum juga memberikan efek. Tujuan studi ini adalah untuk menganalisis faktor resiko yang dapat menyebabkan epilepsi intraktabel pada pasien anak. Penelitian ini menggunakan desain penelitian observasional retrospektif dengan pendekatan systematic review, dimana semua data variable dikumpulkan dari penelitian yang telah dilakukan sebelumnya. Pengumpulan data penelitian ini dikumpulkan dari data penelitian sebelumnya dalam bentuk jurnal penelitian yang dikumpulkan dari database scholar.google.co.id, NCBI, dan science direct. Metode pencarian artikel menggunakan karakteristik PICO (Population, Intervention, Comparison, Outcome) yang lalu data berupa artikel yang telah terkumpul dikelola dengan menggunakan metode Preffered Reporting Items for Systematic Review and Meta-Analysis (PRISMA). Berdasarkan 9 artikel yang telah dikaji, didapatkan bahwa tidak ada studi yang memasukkan faktor usia dalam sebagai faktor risiko epilepsi intraktabel. Odds ratio untuk masing-masing faktor risiko bervariasi, namun faktor risiko yang diteliti paling banyak pada studi yang diinklusi di penelitian ini adalah gangguan tumbuh kembang (8/9), MRI/CT Scan (6/9), dan status epileptikus (5/9). Dari hasil systematic review ini, faktor yang paling berpengaruh terhadap epilepsi intraktabel pada anak adalah gangguan tumbuh kembang dengan odds ratio tertinggi 37,1 yang didapatkan pada studi Wirell et al, dan status epileptikus dengan odds ratio 32,9 yang didapatkan pada studi Yildiz et al. Faktor jenis kelamin durasi waktu kejang, riwayat keluarga epilepsy, dan riwayat kejang demam tidak berpengaruh signifikan terhadap epilepsy intaktabel. Sebagai kesimpulan, dalam penelitian ini ditemukan faktor yang paling berpengaruh terhadap epilepsi intraktabel pada anak adalah gangguan tumbuh kembang dan status epileptikus. Kata Kunci: Faktor Risiko, Epilepsy Intraktabel, Anak
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Putri, Derby Ayudhia Utami Iskandar, i Riri Gusnita Sari. "KARAKTERISTIK DAN TATALAKSANA SINDROM EPILEPSI: SEBUAH TINJAUAN LITERATUR". JURNAL RISET KESEHATAN POLTEKKES DEPKES BANDUNG 16, nr 1 (29.02.2024): 309–16. http://dx.doi.org/10.34011/juriskesbdg.v16i1.2525.
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Definisi dan klasifikasi sindrom epilepsi pertama kali disampaikan oleh International League Against Epilepsy (ILAE) tahun 1985. Menurut ILAE sindrom epilepsi merupakan gangguan epilepsi yang ditandai dengan sekelompok tanda dan gejala, yang dapat terjadi bersamaan. Gejala bergantung pada usia dan serangkaian penyakit penyerta tertentu. Penulis bertujuan menggabungkan berbagai literatur terkini mengenai sindrom epilepsi. Literatur diambil menggunakan database Google Scholar, PubMed, Cochrane Library dalam kurun waktu 4 (empat) tahun, 2019-2023. Studi yang diikutsertakan ke dalam literatur yang sesuai dengan kriteria inklusi meliputi studi yang menjelaskan mengenai sindrom epilepsi dan karakteristiknya. Klasifikasi sindrom epilepsi dibagi berdasarkan jenis kejang dan onset usia. Setiap jenis memiliki karakteristik dan tatalaksana yang berbeda. Sindrom epilepsi pada masa anak yang paling sering dijumpai meliputi, Generalized Tonic-Clonic Seizures Alone/ GTCSA, Childhood Absence Epilepsy/ CAE, Lennox-Gastaut Syndrome/ LGS, West syndrome/ WS, Self-Limited Childhood Epilepsy with Centrotemporal Spikes/ SLCECTS. Dapat disimpulkan bahwa inisiasi pengobatan antikejang pada sindrom epilepsi bergantung pada usia dan efektivitas yang berbeda dari obat antiepilepsi.
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Saputra, Dedyanto Henky. "Peran Diet Ketogenik dalam Tata Laksana Epilepsi". Cermin Dunia Kedokteran 49, nr 11 (1.11.2022): 629–34. http://dx.doi.org/10.55175/cdk.v49i11.318.
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Sejak diperkenalkan pertama kali pada awal abad 19, penggunaan diet ketogenik dalam terapi epilepsi terus berkembang, khususnya untuk kasus epilepsi yang refrakter terhadap terapi farmakologi. Berbagai mekanisme terkait peran diet ketogenik dalam memperbaiki kondisi epilepsi telah diajukan, mulai keterlibatannya dalam regulasi GABA dan glutamat, efek antioksidan, perbaikan metabolisme energi, hingga koreksi kondisi disbiosis. Diet ketogenik adalah terapi non-farmakologis epilepsi yang menjanjikan, saat ini telah masuk dalam guideline NICE di Inggris untuk kasus epilepsi anak yang resisten terhadap terapi obat anti-epilepsi. Since its introduction in the early 19th century, ketogenic diet for the treatment of epilepsy is still being developed, especially for refractory cases. Various mechanisms have been proposed, ranging from its involvement in GABA and glutamate regulation, antioxidant effects, improvement of energy metabolism, to correction of dysbiosis conditions. Ketogenic diet is a promising non-pharmacological therapy for epilepsy; it has been included in UK NICE guidelines for pharmacologically-resistant pediatric epilepsy cases.
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Fitriyani, Fitriyani, Firly Windiyani, Tusy Triwahyuni i Dharmawita Dharmawita. "TINGKAT PENGETAHUAN TENTANG PENYAKIT EPILESPI DAN PERTOLONGAN PERTAMA SAAT SERANGAN PADA MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS MALAHAYATI ANGKATAN 2019 DAN 2021". Jurnal Ilmu Kedokteran dan Kesehatan 10, nr 6 (10.07.2023): 2083–89. http://dx.doi.org/10.33024/jikk.v10i6.9427.
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Abstract: LEVELS OF KNOWLEDGE ABOUT EPILEPSY AND FIRST AID AT ATTACKS IN MEDICAL FACULTY OF MAHAYATI UNIVERSITY AT OF 2019 AND 2021 Epilepsy is a heterogeneous entity with a wide variety of etiologies and clinical features. Status epilepticus is a neurological emergency with morbidity and mortality depending on the duration of the seizure. Researchers want to measure the knowledge of the two batches of 2019 and 2021 because 2019 has taken the neurology block which has already discussed epilepsy, while 2021 has just passed the second semester and has not received epilepsy material in the neurology block. This study found out the Differences in Knowledge Levels of Medical Students Classes of 2019 and 2021 regarding epilepsy and first aid in patients with epilepsy who have seizures. This research is a quantitative study with a cross sectional approach. The population in the study were 142 medical students in the 2019 batch of Malahayati University in Bandar Lampung and 133 in 2021. So the total is 275, the sample is 164 students. Data collection using a questionnaire. Relationship analysis using independent t test. Research Results: Batch 2019 most of the respondents had knowledge in the good category 70 people (85.4%) with an average score of 27.7, Batch 2021 most of the respondents had knowledge in the sufficient category 45 respondents (54.9%) with an average score of 19.9. The statistical test results obtained a p value of 0.000. Conclusion: there are differences in knowledge about epilepsy and first aid for epilepsy patients between students of the 2019 and 2021 general medicine study programs Keywords: Knowledge, epilepsy, first aidAbstrak: TINGKAT PENGETAHUAN TENTANG PENYAKIT EPILEPSI DAN PERTOLONGAN PERTAMA SAAT SERANGAN PADA MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS MALAHAYATI ANGKATAN 2019 DAN 2021 Epilepsi merupakan entitas heterogen dengan etiologi dan gambaran klinik yang sangat bervariasi. Status epileptikus merupakan suatu kondisi kegawatdaruratan neurologis dengan morbiditas dan mortalitas tergantung durasi bangkitan. Peneliti ingin mengukur pengetahuan dua angkatan 2019 dan 2021 dikarenakan 2019 telah mengambil blok neurologi yang sudah membahas penyakit epilepsi sedangkan 2021 baru melewati semester dua dan belum mendapatkan materi epilepsi di blok neurologi. Tujuan penelitian ini diketahui Perbedaan Tingkat Pengetahuan Mahasiswa Kedokteran Angkatan 2019 dan 2021 terhadap penyakit epilepsi dan pertolongan pertama pada pasien epilepsi yang kejang. Penelitian ini merupakan penelitian kuantitatif dengan pendekatan cross sectional. Populasi pada penelitian adalah mahasiswa kedokteran Angkatan 2019 Universitas Malahayati Bandar Lampung sebanyak 142 dan angkatan tahun 2021 sebanyak 133. Jadi totalnya adalah 275, Sampel sebanyak 164 mahasiswa. Pengumpulan data menggunakan kuesioner. Analisis hubungan menggunakan uji t independen. Hasil Penelitian: Angkatan 2019 sebagian besar responden memiliki pengetahuan dalam kategori baik 70 orang (85.4%) dengan nilai rata-rata 27.7, Angkatan 2021 sebagian besar responden memiliki pengetahuan dalam kategori cukup 45 responden (54.9%) dengan nilai rata-rata 19.9. Hasil uji statistik diperoleh nilai p value 0,000. Kesimpulan: ada perbedaan pengetahuan tentang penyakit epilepsi dan pertolongan pertama pada pasien epilepsi antara mahasiswa prodi kedokteran umum angkatan 2019 dan 2021 Kata Kunci: Pengetahuan, penyakit epilepsi, pertolongan pertama
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Sari, Novi Komala, Nina Herlina i Aswan Jhonet. "HUBUNGAN RIWAYAT KEJANG DEMAM DENGAN KEJADIAN EPILEPSI PADA ANAK ≤ 5 TAHUN DI RSUD Dr. H. ABDUL MOELOEK PROVINSI LAMPUNG TAHUN 2018-2019". Jurnal Kebidanan Malahayati 7, nr 3 (31.07.2021): 453–58. http://dx.doi.org/10.33024/jkm.v7i3.4203.
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Background : Epilepsy is a neurological disorder which often found in the world and has the highest incidence in children. The most common risk factor of epilepsy is febrile seizure. Febrile seizure refer to a seizure following by high-fever (>38°C) that often found in the age between 6 month – 5 years old. Objective : This study aim to acknowledge the relation between the febrile sizure history and the incidence of epilepsy found in the children of ≤ 5 years old in RSUD Dr. H. Abdul Moeloek Lampung Province 2018-2019. Methods: This study used an analytic research design with cross sectional approach. The population being used are all pediatric patients in the age of ≤ 5 years which diagnosed with epilepsy in RSUD Dr. H. Abdul Moeloek Lampung Province. Further, the sample being used in this research are 42 people which obtained from total sampling technique. While the statistic test being used is Chi square test. Results :Tthis study is show that 31 children (73.8%) had a febrile seizure history, and 11 children (26.2%) had not a febrile seizure history. Further, this study found that 8 children (19.0%) had a partial awakening epilepsy, and 34 children (81.0%) had a general awakening epilepsy. The result of chi square examination which is (p value 0.032) showed that there is a relation between the febrile seizure history and the incidence of epilepsy found in children at age of ≤ 5 yearch in RSUD Dr. H. Abdul Moeloek Provinsi Lampung in the year of 2018-2019. Conclusion : There is a relation between febrile seizure history and the incidence of epilepsy found in child.Suggestion : It is recommended to be able to pay attention, add insight about febrile seizures and epilepsy, so that mothers don’t panic and know how to overcome them. Keywords : Febrile Seizure, Epilepsy, Child ABSTRAK Latar Belakang : Epilepsi merupakan kelainan neurologis yang sering ditemui di dunia dan insidensinya terbanyak pada masa anak-anak. Faktor risiko epilepsi yang tersering adalah kejang demam. Kejang demam mengacu pada kejang yang berhubungan dengan demam tingkat tinggi (> 38°C) yang sering terjadi pada usia 6 bulan – 5 tahun.Tujuan Penelitian : Penelitian ini bertujuan untuk mengetahui hubungan riwayat kejang demam dengan kejadian epilepsi pada anak ≤ 5 tahun di RSUD Dr. H. Abdul Moeloek Provinsi Lampung 2018-2019. Metode Penelitian : Penelitian ini menggunakan desain penelitian analitik dengan pendekatan cross sectional. Populasi yang digunakan adalah semua pasien anak usia ≤ 5 tahun yang didiagnosis epilepsi di RSUD Dr. H. Abdul Moeloek Provinsi Lampung. Sampel dalam penelitian ini berjumlah 42 orang yang diambil dengan teknik total sampling. Uji statistik yang digunakan adalah uji Chi Square.Hasil Penelitian : Hasil penelitian ini menunjukkan sebanyak 31 anak (73.8%) memiliki riwayat kejang demam, serta 11 anak (26.2%) tidak memiliki riwayat kejang demam. Dan didapatkan sebanyak 8 anak (19.0%) memiliki epilepsi bangkitan parsial, serta 34 anak (81.0%) memiliki epilepsi bangkitan umum. Hasil uji Chi Square yaitu (p value 0.032) terdapat hubungan anatara riwayat kejang demam dengan kejadian epilepsi pada anak ≤ 5 tahun di RSUD Dr. H. Abdul Moeloek Provinsi Lampung Tahun 2018-2019.Kesimpulan : Terdapat hubungan antara riwayat kejang demam dengan kejadian epilepsi pada anak.Saran : Disarankan untuk dapat memperhatikan, menambah wawasan tentang kejang demam dan epilepsi, sehingga ibu tidak panik dan mengetahui cara penanggulangannya. Kata Kunci : Kejang Demam, Epilepsi, Anak.
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Hasibuan, Dede Khairina, i Yazid Dimyati. "Kejang Demam sebagai Faktor Predisposisi Epilepsi pada Anak". Cermin Dunia Kedokteran 47, nr 11 (1.11.2020): 668. http://dx.doi.org/10.55175/cdk.v47i11.1191.
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<p>Kejang demam adalah bangkitan kejang pada anak berumur 6 bulan sampai 5 tahun yang mengalami kenaikan suhu tubuh (di atas 38°C dengan metode pengukuran suhu apapun) yang tidak disebabkan oleh proses intrakranial. Faktor-faktor risiko kejang demam berkembang menjadi epilepsi adalah kelainan neurologis atau perkembangan yang jelas sebelum kejang demam pertama, kejang demam kompleks (KDK), riwayat epilepsi pada orangtua atau saudara kandung, dan kejang demam sederhana (KDS) berulang 4 episode atau lebih dalam satu tahun. Kombinasi faktor risiko tersebut akan lebih meningkatkan risiko epilepsi. Pemberian obat rumatan kejang demam belum terbukti dapat mencegah epilepsi di kemudian hari.</p><p>Febrile seizure is a seizure episode in children aged 6 months to 5 years preceded with an increase in body temperature (above 38° C with any measurement method) not caused by intracranial process. Risk factors to epilepsy are neurological or developmental abnormalities before the first febrile seizure, complex febrile seizures, history of epilepsy in parents or siblings, and simple febrile seizures 4 episodes or more in one year. Combination of these risk factors will increase the likelihood of epilepsy. Febrile seizure prophylaxis medication has not been proven to prevent epilepsy.</p>
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Khansa, Ariesta Nurtria, Dyan Roshinta Laksmi Dewi i Muhammad In’am Ilmiawan. "Hubungan Usia Onset dengan Fungsi Kognitif Pasien Epilepsi di RSUD dr. Soedarso Kota Pontianak, Indonesia". Cermin Dunia Kedokteran 49, nr 11 (1.11.2022): 604–9. http://dx.doi.org/10.55175/cdk.v49i11.313.
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Latar Belakang: Epilepsi adalah gangguan susunan saraf pusat yang ditandai bangkitan spontan berulang. Salah satu faktor yang dapat memengaruhi fungsi kognitif pasien epilepsi adalah usia saat onset. Tujuan: Mengetahui hubungan antara usia saat onset dan fungsi kognitif pasien epilepsi di Poliklinik Saraf RSUD dr.Soedarso Pontianak. Metode: Penelitian analitik observasional cross-sectional. Subjek penelitian berjumlah 36 orang. Variabel bebas penelitian adalah usia pasien saat didiagnosis epilepsi, sedangkan variabel terikat adalah fungsi kognitif pasien epilepsi. Hasil: Distribusi pasien epilepsi terbanyak pada golongan usia dewasa muda (usia 18-25 tahun; 30,5%), laki-laki (55,6%), tingkat pendidikan terakhir SMA (44,4%), tidak bekerja (50%), dan belum menikah (52,8%). Kebanyakan onset epilepsi pada usia 19-60 tahun (58,3%), dengan frekuensi bangkitan tidak sering (75%). Sebagian besar pasien teratur minum obat anti-epilepsi (77,8%) dan telah didiagnosis epilepsi selama 15-30 tahun (44,4%). Sebanyak 9 (25%) pasien epilepsi mengalami penurunan fungsi kognitif yang nyata dan 17 orang (47,2%) kemungkinan (probable) mengalami penurunan fungsi kognitif. Uji korelasi Kendal tau menghasilkan adanya hubungan antara usia saat onset dan fungsi kognitif (p<0,004). Simpulan: Terdapat hubungan antara usia onset dan fungsi kognitif pada pasien epilepsi di Poliklinik Saraf RSUD dr. Soedarso kota Pontianak. Background: Epilepsy is a central nervous system disorder characterized by spontaneous recurrent seizures. Age at onset is one of the factors that may influence cognitive function in epilepsy patients. Aim: To search the relationship between the age at onset and cognitive function among epilepsy patients in the Neurology Polyclinic, dr. Soedarso Regional Hospital, Pontianak City, Indonesia. Methods: An analytic observational study with a cross-sectional method. The total subjects were 36 patients. The independent variable was the age of patients at diagnosis, and the dependent variable was cognitive function. Results: Most epilepsy patients were in young adult age (18-25 years; 30.5%), male (55.6%), with high school as the highest level of education (44.4%), unemployed (50%), and not married (52.8%). The onset of epilepsy is mostly at 19 to 60 years old (58.3%), with infrequent seizure frequency (75%). Most patients are regularly taking anti-epileptic drugs (77.8%), and have been diagnosed for 15-30 years (44.4%). A total of 9 (25%) patients experienced a marked decline in cognitive function, and 17 people (47.2%) experienced a probable decline in cognitive function. Kendal tau correlation test resulted in a relationship between the age at onset and cognitive function (p<0.004). Conclusion: There is a relation between the age at onset and cognitive function among epilepsy patients in dr. Soedarso Regional Hospital of Pontianak City.
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Suwarba, I. Gusti Ngurah Made, i Ni Wayan Kurnia Wati. "Fungsi Kognitif Anak Dengan Epilepsi Umum". Buletin Penelitian Sistem Kesehatan 25, nr 1 (31.05.2022): 12–18. http://dx.doi.org/10.22435/hsr.v25i1.4491.
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Children with epilepsy may experience cognitive impairment due to the effects of structural lesions or seizure activity. This study aims to determine the cognitive function of children with general epilepsy. This study was a cross-sectional design that included children aged 6 to 68 months with general epilepsy in the polyclinic and pediatric ward of Sanglah Hospital Denpasar from September 2013 to January 2015. All children who participated in this study were subjected to a Mullen scale examination. Statistical analysis was performed using Chi-square test and multivariate analysis with logistic regression. In 93 children with general epilepsy, there was a significant correlation between the level of cognitive function and seizure frequency >10 times with an odds ratio 6.067 (95% CI 2.002-18.388, p value 0.001) and seizure duration ≥15 minutes with an odds ratio 6.006 (95% CI 1,817-20,246, p value 0.003). In this study, it can be concluded that seizure frequency >10 times and seizure duration ≥15 minutes in children with general epilepsy have a positive relationship of 6 times with the abnormal cognitive function. Further studies are needed to determine cognitive development of children with general epilepsy.
Abstrak
Anak dengan epilepsi dapat mengalami gangguan kognitif berkaitan dengan efek dari lesi struktural maupun aktivitas kejang. Penelitian ini ditujukan untuk mengetahui fungsi kognitif anak dengan epilepsi umum. Penelitian ini merupakan penelitian dengan desain potong lintang yang mengikutsertakan anak usia 6 sampai 68 bulan dengan epilepsi umum di poliklinik dan ruang perawatan anak RSUP Sanglah Denpasar pada bulan September 2013 hingga Januari 2015. Semua anak yang ikut serta dalam penelitian dilakukan pemeriksaan skala Mullen. Analisis statistik dilakukan dengan uji kai kuadrat dan analisis multivariat dengan regresi logistik. Pada 93 anak dengan epilepsi umum, didapatkan hubungan yang signifikan antara fungsi kognitif dengan frekuensi kejang >10 kali dengan rasio odds 6,067 (nilai p=0,001, 95% CI 2,002-18,388) dan lama kejang ≥15 menit dengan rasio odds 6,006 (nilai p=0,003, 95% CI 1,817-20,246). Pada penelitian ini dapat disimpulkan bahwa frekuensi kejang >10 kali dan lama kejang ≥15 menit pada anak dengan epilepsi umum memiliki hubungan yang positif sebesar 6 kali terhadap fungsi kognitif abnormal. Penelitian lanjutan perlu dilakukan untuk mengetahui perkembangan fungsi kognitif anak dengan epilepsi umum.
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Maulana Yusuf Alkandahri i Isra Qurrata Ayun Eka Putri. "TINGKAT KEPATUHAN PENGGUNAAN OBAT FENITOIN PADA PASIEN EPILEPSI DI RUMAH SAKIT CITRA SARI HUSADA INTAN BAROKAH KARAWANG". BUANA ILMU 5, nr 2 (1.05.2021): 119–28. http://dx.doi.org/10.36805/bi.v5i2.1508.
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Epilepsi merupakan salah satu penyakit otak yang sering ditemukan di dunia. Data World Health Organization (WHO) menunjukkan epilepsi menyerang 70 juta dari penduduk dunia. Penyakit kronis adalah gangguan atau penyakit yang berlangsung lama (berbilang bulan atau tahun), seperti hipertensi, diabetes melitus, kusta, epilepsi, TBC, AIDS, leukimia, dan sebagainya. Penelitian ini bertujuan untuk mengetahui hubungan tingkat kepatuhan minum obat dengan jenis kelamin dan tingkat pendidikan terhadap angka kejadian penyakit epilepsi dengan penggunaan obat antihepilepsi pada pasien epilepsi di Instalasi Rawat Jalan Rumah Sakit Citra Sari Husada Intan Barokah Karawang periode Agustus-November 2020. Penelitian ini bersifat observasional dengan menggunakan rancangan analisis deskriptif cross-sectional. Pengumpulan data dilakukan secara prospektif dan retrosprektif dengan menggunakan data skunder berupa resep pasien epilepsi dan data primer berupa kuesioner yang diberikan kepada pasien rawat jalan di Rumah Sakit Citra Sari Husada Intan Barokah Karawang periode Agustus-November 2020. Penelitian ini dilakukan dengan cara menyebar kuesioner pada responden yang telah memenuhi kriteria inklusi. Diperoleh data sebanyak 96 pasien epilepsi yang menjadi responden. Hasil penelitian ini menunjukkan bahwa tingkat pendidikan merupakan faktor resiko ketidakpatuhan dengan nilai p sebesar 0,536 (p>0,05) dan jenis kelamin juga merupakan faktor resiko ketidakpatuhan dengan nilai p sebesar 0,068 (p>0,05).
Kata kunci: Epilepsi, Kepatuhan, Faktor resiko
Epilepsy is one of the most common brain diseases in the world. World Health Organization (WHO) data shows that epilepsy affects 70 million of the world's population. Chronic disease is a disorder or disease that lasts for a long time (months or years), such as hypertension, diabetes mellitus, leprosy, epilepsy, tuberculosis, AIDS, leukemia, and so on. This study aims to determine the relationship between the level of adherence to taking medication with gender and education level on the incidence of epilepsy with the use of antihepileptic drugs in epileptic patients at the outpatient installation of Citra Sari Husada Intan Barokah Hospital, Karawang period August-November 2020. This study is observational. by using a cross-sectional descriptive analysis design. Data collection was carried out prospectively and retrospectively using secondary data in the form of epilepsy patient prescriptions and primary data in the form of questionnaires given to outpatients at Citra Sari Husada Intan Barokah Hospital, Karawang period August-November 2020. This research was conducted by distributing questionnaires to respondents. who have met the inclusion criteria. Data obtained were 96 epilepsy patients who became respondents. The results of this study indicate that education level is a risk factor for non-compliance with a p value of 0.536 (p> 0.05) and gender is also a risk factor for non-compliance with a p value of 0.068 (p> 0.05).
Keywords: Epilepsy, Obedience, Risk factor
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Sukhov, A. A. "To the clinic "epilepsiae gastricae"". Neurology Bulletin XVIII, nr 1 (6.07.2021): 177–84. http://dx.doi.org/10.17816/nb70828.
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Among the various forms of epileptic development, a clinical group of cases of epilepsy stands out, which some authors call epilepsia gastrica. The genesis and even the ethiology of this group is foggy, and only the clinical picture of epilepsy makes us agree to the temporary allocation of these cases to the epilepsia gastrica group.
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Galante, Iv. "A. Bakk & Gh. Tamasescu Ueber die Aetiologie und Pathogenese der Epilepsie und deren Therapie. Wiener Med. W. No. 17, 1933". Kazan medical journal 29, nr 5-6 (12.01.2022): 489. http://dx.doi.org/10.17816/kazmj89620.
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Bakk and Tamasescu (A. Bakk Gh. Tamasescu Ueber die Aetiologie und Pathogenese der Epilepsie und deren Therapie. Wiener Med. W. No. 17, 1933) give a good concise overview of the etiology, pathogenesis and treatment of epilepsy. Epilepsy is an organic syndrome with a different etiology and multiple pathogenetic factors, which explains that the methods of treatment for epilepsy vary enormously.
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Engel, Jerome. "Evolution of concepts in epilepsy surgery*". Epileptic Disorders 21, nr 5 (październik 2019): 391–409. http://dx.doi.org/10.1684/epd.2019.1091.
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ABSTRACTAt the time of the first meeting of the International League Against Epilepsy (ILAE) in 1909, surgical treatment for epilepsy had been accepted as an alternative therapy for over two decades, but was rarely practiced, considered a last resort for carefully selected patients. Localization was based on ictal semiology and identification of a structural lesion. Very few papers on epilepsy surgery were presented at ILAE meetings or published in Epilepsia during the first half of the 20th century. A modest explosion in interest in epilepsy surgery at mid‐century resulted from recognition that “invisible” epileptogenic lesions could be identified by EEG, especially for temporal lobe epilepsy. Epilepsy surgery received a second boost in popularity toward the end of the 20th century with the advent of structural and functional neuroimaging, and the number of epilepsy centers worldwide doubled between the first Palm Desert conference in 1986 and the second Palm Desert conference in 1992. Neuroimaging also helped to increase application of surgical treatment to infants and young children with severe epilepsies. Epilepsy surgery was accepted as standard of care for drug‐resistant focal epilepsy and was well‐represented at international ILAE congresses and in Epilepsia. Advances continue into the 21st century with the introduction of laser ablation, and palliative neuromodulation approaches, which have greatly increased the population of patients who can benefit from surgery. Modern presurgical evaluation techniques have also made surgical treatment possible in many countries with limited resources. Three randomized control trials now have definitively proved the safety and efficacy of epilepsy surgery, however, this alternative therapy remains under‐utilized even in the industrialized world, where less than 1% of potential candidates are being referred to epilepsy centers. Furthermore, those who are referred receive surgery an average of 20 years after onset of epilepsy, often too late to avoid irreversible disability. The major challenges in realizing the full potential of epilepsy surgery, therefore, are not as much in the continued improvement of the treatment itself, as they are in addressing the treatment gap that is preventing appropriate patients from being referred to full‐service epilepsy centers.
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Funes, B., J. Tellez-Zenteno, L. Hernandez-Ronquillo i A. Wu. "P.031 Waiting times for assessment and epilepsy surgery at the epilepsy program of the University of Saskatchewan". Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 44, S2 (czerwiec 2017): S21. http://dx.doi.org/10.1017/cjn.2017.116.
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Background: Epilepsy surgery remains one of the most underused of all current medical interventions. It is estimated that less than 1% of patients with drug-resistant epilepsy are referred to specialized centers. The average delay from onset of seizures to surgical procedures is between 10 to 20 years Methods: In this study we describe the waiting times from the diagnosis of epilepsy to the assessment and epilepsy surgery at the epilepsy center of the University of Saskatchewan (SEP) Results: We included 70 patients assessed in the epilepy program between 2007 and 2015. Mean age of patients was 42.2+13. The time from the diagnosis of epilepsy to the referral was 16 years. The times for the for assesment and testing were the following: to the first consult with the epileptologist was 208 months, to the neuropsychological test was 201 months, to the video-EEG telemetry 219 months, to the first consult to neurosurgery 227 months and finally to the epilepsy surgery was 238 months. Conclusions: This study shows that patients with complex epilepsy in Canada are waiting significant time to be properly diagnosed and treated. Our study shows similar waiting times to otehrdeveloped countries suggesting a global problem in the reference of patients to epilepsy programs.
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Ernawati, Iin, i Wardah Rahmatul Islamiyah. "Hubungan Kepatuhan Penggunaan Obat Anti Epilepsi terhadap Kejadian Kejang Pasien Epilepsi menggunakan kuesioner ARMS (Adherence Refill Medication Scale)". Journal of Pharmacy and Science 4, nr 1 (30.01.2019): 29–34. http://dx.doi.org/10.53342/pharmasci.v4i1.128.
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ABSTRAKEpilepsi termasuk penyakit kronis otak yang dikarakterisasi dengan kejang berulang (2 kali atau lebih), dimana terjadi gerakan involunter yang melibatkan sebagian tubuh (partial) atau seluruh tubuh (generale), dan seringkali disertai dengan hilangnya kesadaran dan kontrol fungsi saluran cerna atau saluran kemih. Pengobatan epeilepsi sering menggunakan OAE (Obat AntiEpilpsi). Diketahui 70% anak-anak dan dewasa dengan epilepsi berhasil diterapi dengan obat antiepilepsi. Salah satu ukuran manajemen terapi obat pada penyakit epilepsi adalah menurun atau hilangnya kejang, sehingga adanya kejadian kejang menjadi salah satu ukuran pencapaian end outcome. Kejadian kejang dipengaruhi oleh beberapa faktor diantaranya ada tidaknya faktor pemicu kejang dan kepatuhan konsumsi obat antiepilepsi. Penelitian ini merupakan penelitian observasional cross sectional yang dilakukan di poli neurologi Instalasi Rawat Jalan RSUD dr. Soetomo dan Instalasi rawat Jalan RS Universitas Airlangga. Selama penelitian diperoleh 52 pasien epilepsi yang menggunakan obat antiepilepsi. Padapenelitian ini diamati hubungan kepatuhan terhadap adanya kejang pasien epilepsi dalam penggunaan obat anti epilepsi. Pada penelitian ini diketahui nilai koefisien korelasi/ nilai rho (r) sebesar -0,348 dengan nilai p= 0,011 (p<0,05) atau signifikan secara statistik. Hasil tersebut menunjukkan adanya hubungan antara kategori kepatuhan (menggunakan kuesioner ARMS) dengan kejadian kejang, dimana semakin tinggi skor ARMS (dianggap semakin tidak patuh) berbanding lurus dengan peningkatan kejang.Kata kunci: Epilepsi, Kepatuhan, OAE, Kejang, ARMS ABSTRACTEpilepsy is a chronic brain disease characterized by recurrent seizures (2 times or more), in which involuntary movements involve part of the body (partial) or whole body (general). Treatment of epilepsy uses antiepileptic drugs. It is known that 70% of children and adults with epilepsy are successfully treated with antiepileptic drugs. One of measurements of drug therapy management in epilepsy is decreasing or losing seizures, so that the event of seizures is one measure of end outcomes. Seizure events are influenced by severalfactors including the presence or absence of seizure trigger factors and adherence with the consumption of antiepileptic drugs. This study was an observational cross sectional study conducted at the neurology department dr. Soetomo and Airlangga University hospital. This study aims to observe the relationship of adherence of antiepileptic drug consumption with seizures of epilepsy patients. This study observed 52outpatients with epilepsy taking antiepileptic drugs. This study showed that the correlation coefficient / rho value (r) is -0,348 with a value of p = 0.011 (p <0.05). These results indicate that an association between adherence categories (using the arms questionnaire) with the events of seizures, whereas the higher of the arms score (considered to be increasingly disobedient) is directly proportional to the increase in seizures.Keywords: Epilepsy, Adherence, AED, Seizure, ARMS
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Silva, Fabiana Santos, Cibelly Aliny Siqueira Lima Freitas, Dayse Paixão E Vasconcelos, Regina Célia Carvalho Da Silva, Denise Lima Nogueira i Maria da Conceição Coelho Brito. "Situational context of women carriers of epilepsy". Revista de Enfermagem UFPE on line 5, nr 5 (26.06.2011): 1267. http://dx.doi.org/10.5205/reuol.1302-9310-2-le.0505201125.
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ABSTRACTObjective: to reveal the perception of women with epilepsy facing the acquaintance with the disease and investigate the knowledge of the carriers on it. Methodology: case study with qualitative approach, carried out from April to June 2005, through the technique of focus group, semi-structured interview, and participant observation with four epileptic women assisted by the Family Health Strategy in Sinha Saboia de Sobral neighborhood, Ceara, Brazil, approved by the Committee of Ethics in Research Involving Human Subjects of Universidade Estadual Vale do Acarau in Sobral city, Ceará, Brazil, under the Recommendation 250/2005. Results: the information obtained favored the emergence of four categories: Women conceptualizing epilepsy; Response facing the diagnosis of epilepsy; Changes in the family after the diagnosis of epilepsy; The importance of family in the treatment of epilepsy, from the perspective of women. Conclusion: it was found that women lacked knowledge about epilepsy, sometimes they were involved with feelings of sadness, sometimes with resignation, and they expressed, after the diagnosis, feelings of concern and non-acceptance of the disease, stating that the family plays a key role in the treatment of this disease. It was felt, then, that there is a need to finally break free from the social stigma attached to the patients, who often hide from themselves. Descriptors: epilepsy; women; prejudice.RESUMOObjetivo: desvelar a percepção de mulheres portadoras de epilepsia diante da convivência com a doença e investigar o conhecimento das portadoras sobre ela. Metodologia: estudo de caso de abordagem qualitativa, realizado durante os meses de abril e junho de 2005, por meio da técnica de grupo focal, entrevista semiestruturada e observação participante com quatro epilépticas atendidas na Estratégia Saúde da Família do bairro Sinhá Sabóia de Sobral/CE, aprovado Comitê de Ética em Pesquisa Envolvendo Seres Humanos da Universidade Estadual Vale do Acaraú em Sobral/CE, com Parecer n. 250/2005. Resultados: as informações obtidas favoreceram o surgimento de quatro categorias: Mulheres conceituando epilepsia; Resposta diante do diagnóstico de epilepsia; Mudanças na família após o diagnóstico de epilepsia; A importância da família no tratamento da epilepsia, sob a óptica das mulheres. Conclusão: verificou-se que as mulheres apresentavam desconhecimento sobre a epilepsia, estavam envolvidas ora com sentimentos de tristeza, ora de conformação, expressaram, após o diagnóstico, sentimentos de preocupação e não aceitação da doença, afirmando a família ter papel fundamental no tratamento da doença. Percebeu-se, então, que se faz necessário romper definitivamente com o estigma social que acompanha os pacientes, que geralmente se escondem de si mesmos. Descritores: epilepsia; mulheres; preconceito.RESUMENObjetivo: poner de manifiesto la percepción de las mujeres con epilepsia delante de la convivencia con la enfermedady investigar el conocimiento de las portadoras sobre ella. Metodología: estudio de caso de abordaje cualitativa, realizado durante los meses de abril a junio de 2005, a través de la técnica de grupo focal, entrevista semi-estructurada y observación participante con cuatro epilépticas en la Estrategia de Salud de la Familia en el barrio de Sinhá Sabóia de Sobral, Ceará, Brasil, aprobado por el Comité de Ética en Investigación en Seres Humanos de la Universidade Estadual Vale do Acaraú en Sobral, Ceará, Brasil, con el Dictamen 250/2005. Resultados: las informaciones obtenidas favorecieron la aparición de cuatro categorías: Mujeres conceptualizando la epilepsia; Respuesta frente al diagnóstico de la epilepsia; Cambios en la familia después del diagnóstico de la epilepsia; La importancia de la familia en el tratamiento de la epilepsia, desde la perspectiva de las mujeres. Conclusión: se encontró que las mujeres presentaban desconocimiento sobre la epilepsia, estaban enredadas a veces con sentimientos de tristeza, a veces de resignacíon, expresaron, después del diagnóstico, los sentimientos de preocupación y no aceptación de la enfermedad, diciendo que la familia juega un papel clave en el tratamiento de la enfermedad. Se consideró, entonces, que es necesario romper finalmente con el estigma social asociado a los pacientes, que a menudo se esconden de si mismos. Descriptores: epilepsia; mujeres; prejuicio.
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Madani, Al, Fery Ramadhan, Sefa Nur Khalifah, Sukhito Yohanes Tjitradi, Aditya Maulana Perdana Putra, Okta Muthia Sari, Muhammad Ikhwan Rizki i Satrio Wibowo Rahmatullah. "Peningkatan Pengetahuan Mengenai Epilepsi Pada Pasien Poli Saraf Rumah Sakit Ulin Banjarmasin". Jurnal Pengabdian Masyarakat Panacea 2, nr 2 (5.07.2024): 126. http://dx.doi.org/10.20527/jpmp.v2i2.12716.
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Epilepsi adalah kondisi neurologis serius yang terkait dengan stigma, penyakit penyerta psikiatri, dan biaya ekonomi yang tinggi. Masih banyak stigma yang melekat pada orang dengan epilepsi di Indonesia, dan mereka seringkali mengalami diskriminasi dan kesulitan dalam mendapatkan perawatan medis yang tepat. Tujuan promosi kesehatan adalah meningkatkan pengetahuan mengenai epilepsi. Promosi kesehatan menerapkan metode ceramah serta leaflet dalam pemberian edukasi. Evaluasi kegiatan pengabdian ini melalui penilaian kuesoner. Kegiatan Promosi Kesehatan tentang “Epilepsi dan Penanganan saat Kejang” di Rumah Sakit Ulin Banjarmasin dilaksanakan pada hari Kamis, 2 November 2023. Sasaran promosi kesehatan ini adalah pasien dan keluarga pasien yang datang ke poli saraf Rumah Sakit Ulin Banjarmasin. Sebanyak 15 peserta ikut dalam kegiatan promosi kesehatan ini. Hasil dari kegiatan diperoleh terdapat peningkatan pengetahuan sebesar 87% yang ditandai dengan peningkatan nilai skor total kuesioner peserta yang mengikuti kegiatan. Kata Kunci: Promosi Kesehatan, Epilepsi, Pengetahuan Epilepsy is a serious neurological condition associated with stigma, psychiatric comorbidities and high economic costs. There is still a lot of stigma attached to people with epilepsy in Indonesia, and they often experience discrimination and difficulties in getting appropriate medical care. The aim of the health promotion was to increase knowledge about epilepsy. Health promotion applied the lecture method and leaflets in providing education. Evaluation of this service activity through questionnaire assessment. Health Promotion activities on "Epilepsy and Handling during Seizures" at Ulin Hospital Banjarmasin were carried out on Thursday, November 2, 2023. The targets of this health promotion are patients and families of patients who come to the neurology clinic of Ulin Hospital Banjarmasin. A total of 14 participants participated in this health promotion activity. The results of the activity obtained there was an increase in knowledge by 87% which was marked by an increase in the total score of the questionnaire of participants who participated in the activity.
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Wangidjaja, Olivia, i Budi Riyanto Wreksoatmodjo. "Tinjauan atas Epilepsi Pasca-Trauma Kapitis". Cermin Dunia Kedokteran 49, nr 11 (1.11.2022): 610–15. http://dx.doi.org/10.55175/cdk.v49i11.314.
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Epilepsi pasca-trauma kapitis merupakan salah satu disabilitas akibat cedera kepala; yaitu bangkitan epileptik yang terjadi setelah 7 hari sampai bertahun-tahun pasca-trauma kapitis. Epilepsi pasca-trauma kapitis lebih sering ditemukan pada laki-laki, terutama di kelompok usia 0-12 tahun dan 15-27 tahun. Beberapa mekanisme perubahan aktivitas otak yang memicu bangkitan setelah cedera kepala, antara lain peningkatan penanda inflamasi dan sitokin serta perubahan sawar darah-otak; perubahan tersebut berperan penting dalam patogenesis kejang pasca-trauma. Pengobatan anti-konvulsan (OAE) jangka panjang direkomendasikan untuk pasien epilepsi pasca-trauma kapitis. Tingkat remisi epilepsi pasca-trauma kapitis adalah sekitar 25% - 40% dengan pengobatan awal yang dilakukan. Post-traumatic epilepsy, one of the disabilities due to head injury, is epileptic seizures that occur after 7 days to years after head injury. It is more common in males and peaks in the 0-12 year and 15-27 year age groups. Several mechanisms may trigger changes in brain activity after head injury; including increased inflammatory markers and cytokines, and changes in the blood-brain barrier; those changes may play an important role in the pathogenesis of posttraumatic seizures. Long-term anticonvulsant treatment (OAE) is recommended for patients with posttraumatic epilepsy. The remission rate of post-traumatic epilepsy is 25%-40% with early initial treatment.
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Tjandrajani, Anna, Joanne Angelica Widjaja, Attila Dewanti i Amril A. Burhany. "Karakteristik Kasus Epilepsi di Rumah Sakit Anak dan Bunda Harapan Kita pada Tahun 2008-2010". Sari Pediatri 14, nr 3 (17.11.2016): 143. http://dx.doi.org/10.14238/sp14.3.2012.143-6.
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Latar belakang. Diagnosis epilepsi berdasarkan klasifikasi The International League Against Epilepsy(ILAE) 1981 cukup sederhana, namun klinisi kesulitan dalam mengelompokkan karena satu pasien mungkin mengalami lebih dari satu tipe kejang. Maka ILAE 1989 membuat klasifikasi baru untuk memudahkan diagnosis tanpa menggantikan klasifikasi dan definisi sindrom epilepsi sebagai kumpulan tanda dan gejala gangguan epilepsi. Di RSAB Harapan Kita Jakarta belum ada data sindrom epilepsi, hal tersebut menjadi pertimbangan dilakukan penelitian ini. Tujuan.Menilai karakteristik pasien epilepsy anak dan mengelompokkan sindrom epilepsi sesuai klasifikasi ILAE 1989.Metode.Penelitian dengan desain deskriptif, retrospektif menggunakan data rekam medis kasus epilepsi atau kejang tanpa demam yang datang berobat ke RSAB Harapan Kita, pada Januari 2008 sampai dengan Desember 2010. Hasil.Dijumpai 141 pasien anak dengan data riwayat penyakit, pemeriksaan fisis, dan EEG lengkap. Didapatkan 54,6% pasien adalah laki-laki, dan 38,3% mengalami kejang pertama pada usia lebih dari satu bulan. Pada pemeriksaan EEG 82,3% tidak normal. Sedangkan 53,1% pasien termasuk kelompok sindrom idiopatik epilepsi umum.Kesimpulan.Sindrom idiopatik epilepsi umum merupakan kasus terbanyak yang ditemukan di RSAB Harapan Kita Jakarta pada tahun 2008-2010.
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Dzhupanov, G., V. Nikolov i G. Slaveykov. "Alcohol withdrawal seizures, epilepsy and brain trauma". European Psychiatry 67, S1 (kwiecień 2024): S401. http://dx.doi.org/10.1192/j.eurpsy.2024.824.
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IntroductionAlcohol addiction can lead to withdrawal seizures, but most patients do not develop epilesy. In some cases a permanent complication occurs - symptomatic epilepsy. In other cases epilepsy precedes alcohol addiction. Comorbidity may pose serious chalenges to treating clinicians. There are conflicting data regarding relationship between alcohol use, seizures and epilepsy (Scorza CA et al.,CLINICS 2020;75:e1770). Other factors like brain trauma may have impact in genesis of epileptic states as well.ObjectivesEvaluation of interplay between seizures, epilepsy and brain trauma in patients with alcohol use disorder.MethodsAnalysis of a case series in a hospital setting and review of relevant literature.ResultsIn our series of cases the number of patients who have suffered epilepsy before the onset of alcohol use is small. In most of the hospitalized patients epilepsy occurred after the development of alcohol use disorder. In this group we observed that head and brain trauma play role in genesis of seizures and epilepsy and in some instances the reverse happens.ConclusionsOur data indicate the potential role of brain trauma as predisposing and complicating factor in patients who developed seisures and epilepsy. Seizures sometimes increase the risk of brain trauma. Seizures and trauma are important factors in typology of Lesch (Lesch et al. 2011) and a serious evaluation in this direction is improtant, because its diagnostic, therapeutic and prognostic implications. Further clarification in this field is necessary.Disclosure of InterestNone Declared
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Sharobeam, Angelos, Abul Mamun i Roy G. Beran. "030 Management and attitudes towards persons with epilepsy in general practice: how far have we come?" Journal of Neurology, Neurosurgery & Psychiatry 90, e7 (lipiec 2019): A11.1—A11. http://dx.doi.org/10.1136/jnnp-2019-anzan.29.
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IntroductionPrevious surveys of general practitioners (GP) attitudes regarding epilepsy and people with epilepsy (PWE), conducted 20–30 years ago1 2, identified the need for further education in epilepsy care for GPs. This follow up study of GPs in Sydney, Australia, was conducted to determine the degree of changes in knowledge, attitudes and management of PWE, to evaluate if there had been significant improvement during this period.MethodsA piloted questionnaire addressing epilepsy investigations, preferred care provider and attitudes towards epilepsy was developed and completed by a representative sample of Sydney GPs.ResultsA total of 52 completed responses were received. 36 out of 47 GPs (77%) chose neurologists as the most important care giver, followed by the GP (9/47; 18.7%), 25/51 respondents (49%) mentioned they never personally initiated anti-epileptic medication (AEM) and another 27% (14/51 GPs) rarely commenced AEM therapy. 6/50 GPs did not mention EEG as a routine investigation and 21/50 did not mention MRI as routine for PWE. The five most commonly prescribed AEMs, according to frequency were sodium valproate (42), carbamazepine (37), levetiracetam (31), lamotrigine (16) and phenytoin (15). Newer AEMs, available for over a decade in Australia were not mentioned. Emotional, behavioral psychosocial issues were perceived to be more common amongst PWE.ConclusionThe study indicates little perceptual shift regarding GP’s attitudes to epilepsy, and significant deficiencies in knowledge, particularly with regards to investigations and management. The findings reinforce a need for more formal training of GPs caring for PWE.ReferencesBeran RG, Read T. A survey of doctors in Sydney, Australia: perspectives and practices regarding epilepsy and those affected by it. Epilepsia. 1983;24(1):79–104.Frith JF, Harris MF, Beran RG. Management and attitudes of epilepsy by a group of Sydney general practitioners. Epilepsia. 1994;35(6):1244–7.
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Shah, Bela, Dhara Gosai, Sonu Akhani, Mehul Jadav i Nirav Rathod. "Study of Epilepsy and its Correlation with Neuroimaging and Drug Therapy". Annals of International Medical and Dental Research 8, nr 1 (15.01.2022): 43–49. http://dx.doi.org/10.53339/aimdr.2022.8.1.7.
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Background: Thousands of people in the world suffer from epilepsy. Inspite of modern advances, it can be controlled in only 80% of treated once. Diagnosis and treatment of epilepsy is still challenged. The present study is attempted to highlight the importance of clinical findings and role of EEG and CT scan and MRI in diagnosis of epilepsy2.Aim:To study the incidence and epidemiological profile, various types of epilepsy and correlation with MRI, CT SCAN, EEG and the effectiveness of various Anti epilepticdrugs in different types of epilepsy. Settings and Design: This is a prospective study carried out at Civil Hospital, Ahmedabad.Methods:All the patients having 2 and/or more unprovoked seizures and already enrolled patients in epilepsy clinic in 1 year duration from January 1,2020 to December 31,2020 were included.Results &Conclusions:Out of 6930 total admissions, 163 patients with epilepsy were enrolled in this study from age group of 1 month to 12 years. Out of 163 patients, 97 were male and 66 were female. Most common age group affected is of 1-5 years. 128 patients (78.62%) were of generalized epilepsy and 35 patients were of partial epilepsy. Most common precipitating factor in epilepsy is inadequate drug dosages (45%). 45 patients (22.7%) have developmental delay. Abnormal EEG findings were present in 123 patients (75.46%). Abnormal MRI findings were present in 37 patients (22.7%). CT scan was done in 56 patients, 20 were abnormal. 107 patients were on monotherapy and 56 patients were on polytherapy. Valproate is most commonly used drug (76.6%).
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Maryam, Izadi Laybidi. "Epilepsy Management during the COVID-19 Pandemic in Epilepsy Monitoring Unit". Journal of Clinical Cases & Reports 3, S4 (31.12.2020): 22–24. http://dx.doi.org/10.46619/joccr.2020.3.s4-1006.
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Ulitin, A. Yu, G. V. Odintsova, V. G. Nezdorovina i S. M. Malyshev. "Dostoevsky’s epilepsy". Russian journal of neurosurgery 23, nr 3 (26.10.2021): 113–21. http://dx.doi.org/10.17650/1683-3295-2021-23-3-113-121.
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There is a lot of evidence that a great Russian writer and essayist Fyodor Mikhailovich Dostoevsky suffered from epilep‑ sy. Not only this disease had influence on Dostoevsky’s personality and social life, but also affected his creative work. Dostoevsky is believed to suffer from mesiobasal temporal lobe epilepsy with an ecstatic aura – a form named after him afterwards.
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Mlinar, Simona, Zvonka Rener Primec i Davorina Petek. "Psychosocial Factors in the Experience of Epilepsy: A Qualitative Analysis of Narratives". Behavioural Neurology 2021 (26.07.2021): 1–9. http://dx.doi.org/10.1155/2021/9976110.
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Introduction. Epilepsy is a complex disease. The consequences of epilepsy are varied and manifested in all aspects of people with epilepsy’s (PWE) lives. The purpose of this study was to define individual experiences of epilepsy, expressed in narratives, and to find the stem of each narrative—a core event in the PWE’s experience of the disease around which they structure their overall narrative. Method. A qualitative, phenomenological research method was used. We conducted semistructured interviews with 22 PWE and analysed the content using a combination of inductive and deductive methods, based on which we determined the stem narratives. Results. The stem narrative of the epilepsy narrative is an important life experience of PWE. We divided the stem narratives into four groups: lifestyle changes, relationship changes, the consequences of the inciting incident, and the limitations of the disease. In our study, we found that the stem narrative was, in all but one case, a secondary (psychosocial) factor resulting from epilepsy, but not its symptom (epileptic seizure). The stem narrative, where aspects of life with epilepsy are exposed, points to a fundamental loss felt by PWE. Conclusion. The narrative of the experience of epilepsy has proven to be an important source of information about the disease and life of PWE and also about the aspects at the forefront of life with epilepsy. The secondary epilepsy factors that we identified in the stem narratives were the greatest burden for PWE in all cases but one.
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Reuvekamp, Marieke. "Frontale epilepsie; impact op cognitie en gedrag bij kinderen". Epilepsie, periodiek voor professionals 19, nr 3 (1.09.2021): 22–23. http://dx.doi.org/10.54160/epilepsie.11434.
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Lydia van den Berg promoveerde op 19 april 2021 aan de Rijksuniversiteit Groningen op het proefschrift Epilepsy out of control; when frontal lobe epilepsy becomes more than seizures. In haar proefschrift is er vooral aandacht voor executieve functies bij kinderen met frontale epilepsie. Welke gedrags- en cognitieve problemen ondervinden deze kinderen en verschilt de rapportage hierover van leerkrachten en ouders?
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Suhaimi, M. Luthfi, Iskandar Syarif, Eva Chundrayetti i Rahmi Lestari. "Faktor Risiko Terjadinya Epilepsi pada Anak Palsi Serebral". Jurnal Kesehatan Andalas 9, nr 2 (1.08.2020): 225. http://dx.doi.org/10.25077/jka.v9i2.1282.
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Pada anak yang menderita palsi serebral kemungkinan akan mengalami peningkatan risiko terjadinya epilepsy. Setiap perubahan pada otak dapat menjadi faktor risiko terjadinya epilepsi dengan berbagai manifestasi klinis. Tujuan: Mengetahui hubungan antara faktor risiko dengan terjadinya epilepsi pada anak palsi serebral di RSUP Dr. M. Djamil Padang. Metode: Desain peneltian ini adalah cross-sectional study yang dilaksanakan pada Agustus 2018 sampai Desember 2019. Subjek palsi serebral diperoleh secara consecutive sampling, dengan jumlah minimal 60 subjek. Faktor risiko yang diteliti meliputi asfiksia, persalinan vakum ekstraksi, berat badan lahir rendah, prematuritas dan kejang neonatal. Uji statistik menggunakan Chi-square test dan Fisher’s exact test, dengan batas kemaknaan p<0,05. Hasil: Pada 60 pasien palsi serebral, ditemukan 39 pasien (65%) menderita epilepsi dan 21 pasien (35%) tidak menderita epilepsi. Perbandingan jenis kelamin perempuan dan laki-laki 1,2:1. Epilepsi umum merupakan tipe epilepsi yang paling banyak ditemukan (76,9%), pengobatan secara politerapi hampir sama banyak dengan monoterapi. Asfiksia, persalinan vakum ekstraksi, berat badan lahir rendah, prematuritas dan kejang neonatal tidak bermakna sebagai faktor risiko epilepsi pada anak palsi serebral. Simpulan: Tidak terdapat hubungan antara asfiksia, persalinan vakum ekstraksi, berat badan lahir rendah, prematuritas dan kejang neonatal dengan terjadinya epilepsi pada anak palsi serebral.Kata kunci: cerebral palsy, epilepsy, risk factors
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Knezevic-Pogancev, Marija. "Cerebral palsy and epilepsy". Medical review 63, nr 7-8 (2010): 527–30. http://dx.doi.org/10.2298/mpns1008527k.
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Introduction. Cerebral palsy is the most common cause of physical disability in early childhood. Epilepsy is known to have a high association with cerebral palsy. All types of epileptic seizures can be seen in patients with cerebral palsy. Complex partial and secondary generalized ones are the most frequent seizure types. In persons with cerebral palsy and mental retardation, the diagnosis of epilepsy presents unique difficulties. Generally they are not able to describe the epileptic events themselves, parents are not able to describe them without fear and persons trained in epilepsy witness the events only rarely. Some syndromes, such as infantile spasms, West and Lennox-Gastaut syndrome, are particularly frequent, whereas children with cerebral palsy are rarely free of epilesy. It has been observed that epileptic seizures in children with cerebral palsy tend to have an earlier onset; they often appear in children with cerebral palsy and mental retardation; they are more severe in patients with a more severe degree of cerebral palsy. The overall outcome of seizures in children with cerebral palsy is poor, requiring prolonged course of antiepileptic medications, polytherapy with higher incidence of refractory seizures and hospital admissions for status epilepticus. The presence of a neurological deficit, as well as cerebral palsy, does not necessarily mean a poor prognosis after the discontinuation of antiepileptic drugs, but the risk of a relaps in persons with cerebral palsy is high. Aim. The objective of the paper was to show the relationship between cerebral palsy and epilepsy and to determine the occurrence, associated factors, nature and prognosis of epilepsy in children with cerebral palsy.
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Prontera, P., P. Sarchielli, S. Caproni, C. Bedetti, LM Cupini, P. Calabresi i C. Costa. "Epilepsy in hemiplegic migraine: Genetic mutations and clinical implications". Cephalalgia 38, nr 2 (6.01.2017): 361–73. http://dx.doi.org/10.1177/0333102416686347.
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Objective We performed a systematic review on the comorbidities of familial/sporadic hemiplegic migraine (F/SHM) with seizure/epilepsy in patients with CACNA1A, ATP1A2 or SCN1A mutations, to identify the genotypes associated and investigate for the presence of mutational hot spots. Methods We performed a search in MEDLINE and in the Human Gene Mutation and Leiden Open Variation Databases for mutations in the CACNA1A, ATP1A2 and SCN1A genes. After having examined the clinical characteristics of the patients, we selected those having HM and seizures, febrile seizures or epilepsy. For each gene, we determined both the frequency and the positions at protein levels of these mutations, as well as the penetrance of epilepsy within families. Results Concerning F/SHM-Epilepsy1 (F/SHME1) and F/SHME2 endophenotypes, we observed a prevalent involvement of the transmembrane domains, and a strong correlation in F/SHME1 when the positively charged amino acids were involved. The penetrance of epilepsy within the families was highest for patients carrying mutation in the CACNA1A gene (60%), and lower in those having SCN1A (33.3%) and ATP1A2 (30.9%) mutations. Conclusion Among the HM cases with seizure/epilepsy, we observed mutational hot spots in the transmembrane domains of CACNA1A and ATP1A2 proteins. These findings could lead to a better understanding of the pathological mechanisms underlying migraine and epilepsy, therein guaranteeing the most appropriate therapeutic approach.
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Serrano-Castro, Pedro J., Jose Angel Mauri-Llerda, Francisco José Hernández-Ramos, Juan Carlos Sánchez-Alvarez, Beatriz Parejo-Carbonell, Pablo Quiroga-Subirana, Fernando Vázquez-Gutierrez i in. "Adult Prevalence of Epilepsy in Spain: EPIBERIA, a Population-Based Study". Scientific World Journal 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/602710.
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Background. This study assesses the lifetime and active prevalence of epilepsy in Spain in people older than 18 years.Methods. EPIBERIA is a population-based epidemiological study of epilepsy prevalence using data from three representative Spanish regions (health districts in Zaragoza, Almería, and Seville) between 2012 and 2013. The study consisted of two phases: screening and confirmation. Participants completed a previously validated questionnaire (EPIBERIA questionnaire) over the telephone.Results. A total of 1741 valid questionnaires were obtained, including 261 (14.99%) raising a suspicion of epilepsy. Of these suspected cases, 216 (82.75%) agreed to participate in phase 2. Of the phase 2 participants, 22 met the International League Against Epilepsy’s diagnostic criteria for epilepsy. The estimated lifetime prevalence, adjusted by age and sex per 1,000 people, was 14.87 (95% CI: 9.8–21.9). Active prevalence was 5.79 (95% CI: 2.8–10.6). No significant age, sex, or regional differences in prevalence were detected.Conclusions. EPIBERIA provides the most accurate estimate of epilepsy prevalence in the Mediterranean region based on its original methodology and its adherence to ILAE recommendations. We highlight that the lifetime prevalence and inactive epilepsy prevalence figures observed here were compared to other epidemiological studies.
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Shafiq, Majid, Mansoor Tanwir, Asma Tariq, Ayesha Saleem, Monaa Zafar i Ali Khan Khuwaja. "Myths and fallacies about epilepsy among residents of a Karachi slum area". Tropical Doctor 38, nr 1 (styczeń 2008): 32–33. http://dx.doi.org/10.1258/td.2006.006311.
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Misconceptions about epilepsy may explain the considerable stigma accompanying it. We aimed to identify such fallacies through questionnaire-based interviews of 487 adult residents of a slum area in Karachi, Pakistan. Of those interviewed, 25% believed that epilepsy was caused by evil spirits, black magic and envy by others – those without a school education were more likely to hold these views ( P < 0.05). Perceived complications included impotence and cancer. Shoe-sniffing was considered a treatment modality by 13%. It appears that misconceptions abound regarding epilepsy's causes, complications and methods of treatment. However, those who had received a school education were less likely to link epilepsy with supernatural phenomena.
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P., Viswajyothi, i K. Vinod Kumar. "Utility of “International League against Epilepsy (ILAE)” Classification in Patients with Epilepsy". International Journal of Neurology and Neurosurgery 10, nr 3 (2018): 235–41. http://dx.doi.org/10.21088/i6nns.0975.0223.10318.15.
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Jayaram, Shoba, Modhi Alkhaldi i Asim Shahid. "The Role and Controversies of Electroencephalogram in Focal versus Generalized Epilepsy". Journal of Pediatric Epilepsy 10, nr 02 (19.02.2021): 058–64. http://dx.doi.org/10.1055/s-0041-1722869.
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AbstractAs early in 1935, Gibbs et al described electroencephalogram (EEG) features of large slow waves seen in “petit mal” seizures and change in background rhythm to a higher frequency, greater amplitude pattern in “grand mal” seizures. Studies have shown many typical EEG features in focal onset as well as generalized epilepsies.2 3 It is usually easy to delineate focal epilepsy cases when EEG onset of seizures is clear as seen in Benign focal epileptiform discharges of childhood.4 However, it is not uncommon to see cases where epileptiform discharges are not very clear. For example, there can be secondary bilateral synchrony or generalized onset of epileptiform discharges in some cases of focal epilepsy5 and nongeneralized EEG features is cases of generalized epilepsy like absence seizures.6 The awareness of occurrence of focal clinical and EEG features in generalized epilepsy is particularly important to help to select appropriate AEDs and also to avoid inappropriate consideration for epilepsy surgery.7 Lüders et al8 have shown that multiple factors like electroclinical seizure evolution, neuroimaging (both functional and anatomical) have to be analyzed in depth before defining an epileptic syndrome. Here, we are providing few examples of different situations where it is still mysterious to figure out focal onset seizures with secondary generalization versus primary generalized epilepsy.
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Min, Li Li, i J. W. A. S. Sander. "Projeto demonstrativo em epilepsia no Brasil". Arquivos de Neuro-Psiquiatria 61, nr 1 (marzec 2003): 153–56. http://dx.doi.org/10.1590/s0004-282x2003000100033.
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A epilepsia é a condição neurológica grave de maior prevalência no mundo. Infelizmente, a maioria dos pacientes com epilepsia nos países em desenvolvimento não recebem tratamento adequado e sofrem estigmatização pelo diagnóstico. Diante deste cenário, em 1997 foi lançada uma Campanha Global Contra Epilepsia liderada pela Organização Mundial da Saúde, a Internacional League Against Epilepsy, e International Bureau for Epilepsy. A Campanha entrou na sua segunda fase em 2001 com os projetos demonstrativos que estão em curso na China, Zimbábue, Senegal e recentemente no Brasil. A finalidade do projeto demonstrativo é mostrar através de avaliação metodológica que é possível estabelecer um modelo de atendimento integral aos pacientes com epilepsia. O projeto demonstrativo brasileiro tem como regiões de atuação Campinas e São José de Rio Preto. Uma Task Force foi instituída para estudar a expansão da atuação para outras áreas do país.
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Devinsky, Orrin. "Is Behavior in Temporal Lobe Epilepsy Different than in Other Epilepsies? the Jury is Out". Epilepsy Currents 7, nr 4 (lipiec 2007): 95–96. http://dx.doi.org/10.1111/j.1535-7511.2007.00184.x.
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Interictal Depression, Anxiety, Personality Traits, and Psychological Dissociation in Patients with Temporal Lobe Epilepsy (TLE) and Extra-TLE. Swinkels WA, van Emde Boas W, Kuyk J, van Dyck R, Spinhoven P. Epilepsia 2006;47(12):2092–2103. PURPOSE: This study was performed to investigate the relation between symptoms of interictal depression, anxiety, personality traits, and psychological dissociation with the localization and lateralization of the epileptogenic zone in patients with partial epilepsy. METHODS: All patients were diagnosed according to the localization-related concept of the 1989 International League Against Epilepsy (ILAE) Classification of Epilepsies and Epileptic Syndromes, and the localization and lateralization of the epileptogenic zone was established by using the clinical criteria for noninvasive presurgical evaluation. This resulted in 67 patients with temporal lobe epilepsy (TLE) and 64 patients with extra-TLE. All patients were assessed on the various aspects of psychopathology by using a comprehensive battery of standardized diagnostic instruments. RESULTS: We did not find the hypothesized excess of psychiatric symptoms in patients with (mesial) TLE in comparison with patients with extra-TLE. We also found no differences between patients with the lateralization of epilepsy in the left versus the right hemisphere. CONCLUSIONS: TLE per se cannot be considered a risk factor in developing more or more severe symptoms of psychopathology in patients with partial epilepsy. Concomitant factors, such as the duration of epilepsy, seizure frequency, and frontal lobe dysfunction may play an additional role. Our findings support the hypothesis of a multifactorial explanation for the psychiatric symptoms in patients with epilepsy.
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Quintana, Verónica Joomayra, Eduardo Javier Barragán Pérez, Daniel Eduardo Álvarez Amado i Juan Carlos García Beristaín. "APLICACIÓN DE ESCALA DE EVALUACIÓN PEDIÁTRICA DEL INVENTARIO DE DISCAPACIDAD-PRUEBA ADAPTATIVA POR COMPUTADORA (PEDI-CAT) EN PACIENTES CON EPILEPSIA." Enfermería Investiga 7, nr 1 (3.01.2022): 11. http://dx.doi.org/10.31243/ei.uta.v7i1.1472.2022.
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Introducción: La epilepsia representa una de las principales causas de morbilidad en neuropediatría. El inicio temprano de las crisis epilépticas, se relaciona con menor desempeño intelectual a largo plazo, y alteraciones en las habilidades adaptativas. Objetivo: Aplicar escala de evaluación pediátrica del inventario de discapacidad-prueba adaptativa por computadora (PEDI-CAT) en pacientes pediátricos con epilepsia. Métodos: Se realizó un estudio de nivel descriptivo, tipo observacional, prospectivo, trasversal y analítico, realizado el Departamento de Neurología Pediátrica del Hospital Infantil de México Federico Gómez, en la Ciudad de México. El reclutamiento de los pacientes fue durante abril y diciembre de 2020. Resultados: los pacientes con epilepsia presentaron un percentil <5 en sus habilidades de movilidad 22 (35,4%), actividades diarias 19(30,6%), social-cognitivas 19(30,6%), lo que significa que están por debajo de rango normal comparado con niños de su edad. Conclusiones: los pacientes con epilepsia presentaron un percentil <5 en el dominio de actividades diarias, movilidad y social-cognitiva, lo que significa que están por debajo de rango normal comparado con niños de su edad. Por tanto, la epilepsia debe ser considerado un trastorno que afecta la capacidad adaptativa de los pacientes y no sólo una patología cuya manifestación son las crisis, su detección temprano con el uso de escalas como PEDI-CAT se traduce en la identificación y planificación de estrategias terapéuticas eficaces para mejorar calidad de vida de los pacientes Palabras Clave: Epilepsia, Conducta Adaptativa, Trastornos del Neurodesarrollo. ABSTRACT Introduction: Epilepsy represents one of the main causes of morbidity in pediatric neurology. The early onset of epileptic seizures is related to lower long-term intellectual performance, and alterations in adaptive skills. Objective: To apply the Pediatric Evaluation of Disability Inventory Computer Adaptive Test (PEDI-CAT) report in pediatric patients with epilepsy. Methods: A descriptive, observational, prospective, cross-sectional and analytical study was carried out in the Department of Pediatric Neurology at Hospital Infantil de México Federico Gómez, in Mexico City. Patient recruitment took place between April and December 2020. Results: patients with epilepsy presented a <5 percentile in their mobility skills 22 (35.4%), daily activities19 (30.6%), social-cognitive 19 (30.6%), which means that they are below of normal range compared to children his age. Conclusions: patients with epilepsy presented a <5 percentile in the domain of daily activities, mobility and social-cognitive, which means that they are below the normal range compared to children of their age. Therefore, epilepsy should be considered a disorder that affects the adaptive capacity of patients and not just a pathology whose manifestation is seizures, its early detection with the use of scales such as PEDI-CAT translates into the identification and planning of strategies effective therapeutics to improve the quality of life of patients Keywords: Epilepsy, Adaptation, Psychological, Neurodevelopmental Disorders.
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Sharma, Surabhi. "Psychiatric Aspects of Epilepsy". Journal of Advanced Research in Psychology & Psychotherapy 03, nr 3&4 (16.01.2021): 15–20. http://dx.doi.org/10.24321/2581.5822.202009.
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A seizure is defined as transient change in neurological functioning which is characterised by hypersynchronous discharges of neurons in the brain regions whereas epilepsy is defined as a syndrome consisting of various recurrent seizures and it is associated with the psychological and neuropathological effects. Early recognition and management of psychiatric disorders in patients with epilepsy is extremely important, because it improves the quality of life and aids in better seizure control. Newer antiepileptics with less interaction with psychotropics and less behavioural manifestations should be used for management of epilepsy; and psychotropics having low potential for lowering seizure threshold are generally preferred. A holistic approach to assess psychiatric comorbidity and judicious use of medicine can help in comprehensive patient care planning and reduced health burden.
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Kirabira, Joseph, Ben Jimmy Forry, Robyn Fallen i Bernard Sserwanga. "Perceived stigma and school attendance among children and adolescents with epilepsy in South Western Uganda". African Health Sciences 20, nr 1 (20.04.2020): 376–82. http://dx.doi.org/10.4314/ahs.v20i1.43.
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Background: Epilepsy is a neurological disorder that has a high worldwide prevalence with eighty percent of the global burden being in low and middle-income countries. There is a high level of perceived stigma among children and adolescents with epi- lepsy, which has severe debilitating effects and affects school attendance.
Objective: To assess the effect of perceived stigma on school attendance patterns among children and adolescents with epilepsy.
Methods: We conducted a cross sectional study among 191 children and adolescents aged from 6-18 years with epilepsy at one large semi-urban hospital and a small rural health center in SouthWestern Uganda. Epilepsy-related perceived stigma was measured using the adapted Kilifi Stigma Scale of Epilepsy and school attendance patterns were assessed using a piloted inves- tigator-designed questionnaire.
Results: Children with high-perceived stigma were more likely to have never attended school (13.8%) or started school late (average age 5.7 years) compared to those with low-perceived stigma (average age 4.9 years). Additionally, those with high epilep- sy-related perceived stigma repeated classes 2.5 times more compared to those with low-perceived stigma.
Conclusion: These preliminary findings suggest correlation between high-perceived stigma and disrupted school attendance patterns among children and adolescents with epilepsy, hence the need to address this social challenge.
Keywords: Epilepsy; perceived stigma; school attendance; children; adolescents; Uganda.
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Dimova, Rumyana, Greta Grozeva, Nevena Chakarova, Polina Tsarkova i Tsvetalina Tankova. "GAD-65 autoantibody associated epilepsy". Journal of Pediatric Endocrinology and Metabolism 33, nr 6 (21.05.2020): 817–20. http://dx.doi.org/10.1515/jpem-2019-0395.
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AbstractObjectivesThe aim of this report is to describe a case of GAD-65 autoantibody associated epilepcy, diagnosed long before the onset of autoimmune diabetes.Case presentationThis report presents a 36-year-old female with type 1 diabetes, diagnosed at the age of 26, and a cryptogenic focal epilepsy with complex partial seizures, with duration of 2–3 min and frequency of 5–6 per month, diagnosed at 16 years of age. Electroencephalography revealed epileptiform abnormalities temporally and centro-parietally on the left and temporally on the right with forward propagation on both sides. Due to the drug refractory seizures, titers of GAD-65 autoantibodies were examined (19 years after the diagnosis of epilepsy and 9 years after the diagnosis of diabetes) and were found to be elevated in serum and cerebrospinal fluid, strongly supporting its autoimmune genesis. Insulin pump therapy was used in this patient with a beneficial effect on glycemia.ConclusionsAutoimmune epilepsy is a clinical entity and should be taken into consideration in patients with other autoimmune diseases, especially diabetes, and with drug refractory seizures, even preceding the onset of diabetes. Achieving stable glycemic control, including the usage of the new technologies in type 1 diabetes treatment, is vital in these cases.
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Rouhl, Rob. "Een onderzoek naar post-stroke epilepsie". Epilepsie, periodiek voor professionals 19, nr 4 (17.12.2021): 31–33. http://dx.doi.org/10.54160/epilepsie.11404.
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Op 16 april 2021 promoveerde Julia van Tuijl aan de Universiteit Maastricht op het proefschift Post-stroke epilepsy. Haar klinisch gerichte onderzoek geeft nieuwe inzichten in de epilepsie zoals deze kan ontstaan na een beroerte (herseninfarct of hersenbloeding), de post-stroke epilepsie.
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Moreira, Gabriela Carrion Degrande, i Antonia Regina Ferreira Furegato. "Reabilitação psicossocial de pessoas com transtornos mentais e epilepsia". Revista Recien - Revista Científica de Enfermagem 11, nr 36 (15.12.2021): 598–601. http://dx.doi.org/10.24276/rrecien2021.11.36.598-601.
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Durante a evolução da humanidade, a pessoa com epilepsia sofreu e sofre com estigmas e temores. Na pandemia da COVID-19, reabilitação psicossocial, cuidado diferenciado, ressignificação do sentido da vida dessas pessoas e de seus cuidadores, tornam-se essenciais. Enfermeiros são profissionais que devem ser preparados para atuarem junto à pessoa com epilepsia, seu familiar e à equipe de saúde, desenvolvendo ações nos diferentes níveis de atenção à saúde. A observação clínica e as intervenções e cuidados de enfermagem passam por várias ópticas. São fundamentais no processo de reabilitação psicossocial, a educação em saúde e o estímulo ao autocuidado com intervenções inovadoras e individualizadas, promovendo autonomia das pessoas com epilepsia. Consideramos importante promover estudos e programas de reabilitação psicossocial dirigidos às pessoas com epilepsia, especialmente as que apresentam transtorno mental associado tendo em vista a sua organização psicossocial na vivência simultânea de duas doenças crônicas.Descriptores: Reabilitação Psiquiátrica, Enfermagem, Epilepsia, Transtornos Mentais. Psychosocial rehabilitation of people with mental disorders and epilepsyAbstract: During the evolution of humanity, the person with epilepsy suffered and suffers from stigmas and fears. In the COVID-19 pandemic, psychosocial rehabilitation, differentiated care, re-signifying the meaning of life of these people and their caregivers, become essential. Nurses are professionals who must be prepared to work with the person with epilepsy, their family members and the health team, developing actions at different levels of health care. Clinical observation and nursing interventions and care go through several perspectives. Health education and the encouragement of self-care with innovative and individualized interventions are essential in the psychosocial rehabilitation process, promoting autonomy for people with epilepsy. We consider it important to promote studies and psychosocial rehabilitation programs aimed at people with epilepsy, especially those with associated mental disorders, in view of their psychosocial organization in the simultaneous experience of two chronic diseases.Descriptores: Psychiatric Rehabilitation, Nursing, Epilepsy, Mental Disorders. Rehabilitación psicosocial de personas con trastornos mentales y epilepsiaResumen: Durante la evolución de la humanidad, la persona con epilepsia sufrió y sufre estigmas y miedos. En la pandemia del COVID-19, la rehabilitación psicosocial, la atención diferenciada, resignificando el sentido de la vida de estas personas y sus cuidadores, se vuelven imprescindibles. Las enfermeras son profesionales que deben estar preparados para trabajar con la persona con epilepsia, sus familiares y el equipo de salud, desarrollando acciones en los diferentes niveles asistenciales. La observación clínica y las intervenciones y cuidados de enfermería atraviesan varias perspectivas. La educación para la salud y el fomento del autocuidado con intervenciones innovadoras e individualizadas son fundamentales en el proceso de rehabilitación psicosocial, promoviendo la autonomía de las personas con epilepsia. Consideramos importante promover estudios y programas de rehabilitación psicosocial dirigidos a personas con epilepsia, especialmente aquellas con trastornos mentales asociados, de cara a su organización psicosocial en la vivencia simultánea de dos enfermedades crónicas.Descriptores: Rehabilitación Psiquiátrica, Enfermería, Epilepsia, Trastornos Mentales.
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Ejeliogu, E. U., i A. Courage. "Prevalence and factors associated with non-adherence to antiepileptic drugs among children with epilepsy in Jos, Nigeria". Nigerian Journal of Paediatrics 47, nr 3 (6.08.2020): 240–45. http://dx.doi.org/10.4314/njp.v47i3.8.
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Background: Childhood epilepsy causes a tremendous burden for the child, the family, society as well as the healthcare system. Adherence toantiepileptic drugs (AEDs) is key to treatment success, one of the main causes of unsuccessful treatment for epilepsy is poor adherence to medications. Nonadherence in children with epilepsy presents a potential ongoing challenge for achieving a key therapeutic goal of seizure control.Aim: To determine the prevalence and factors associated with nonadherence to AEDs among children with epilepsy at Jos University Teaching Hospital, Jos, Nigeria.Methodology: This cross sectional study was done to assess the prevalence and factors associated with non-adherence to AEDs among children with epilepsy from November 2019 to February 2020. A structured questionnaire was used to collect relevant information on the adherence of studysubjects to AEDs based on self/ caregiver report. Part of the questionnaire was derived from Morisky Medication Adherence Scale (MMAS-8).Results: One hundred and ninety four subjects were recruited for the study. The prevalence of nonadherence to AEDs was 44.8%. Factors significantly associated with non-adherence were low socioeconomic status, multiple drug therapy and long duration of treatment. The main reasons for nonadherence were financial constraint, forgetfulness, lack of improvement and medication side effects.Conclusion: Non-adherence to medication is common among children with epilepsy and it hampers the key therapeutic goal of seizure control. Improving per capita income of families, providing universal health insurance, medication reminders and appropriate education/counseling will reduce non-adherence and improve the long term outcome of childhood epilepsy in our region.
Key words: Epilepsy, Children, Ant i -epilept ic drugs, Nonadherence, Prevalence, Associated factors, Jos, Nigeria.
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Siegel, Adrian M. "Epilepsy surgery of extratemporal epilepsy". Therapeutische Umschau 58, nr 11 (1.11.2001): 676–83. http://dx.doi.org/10.1024/0040-5930.58.11.676.
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Epilepsie gehört zu den häufigsten neurologischen Erkrankungen. Obwohl bei den meisten Patienten die Erkrankung mit Medikamenten zufriedenstellend eingestellt werden kann, bleiben rund 30 bis 40% der Patienten mit fokaler Epilepsie therapierefraktär. Bei diesen Patienten stellt die Epilepsiechirurgie eine wichtige Behandlungsoption dar. Bei der operativen Epilepsiebehandlung der häufigsten fokalen Epilepsieform, der Temporallappenepilepsie, zeigen sich sehr gute Resultate bezüglich postoperativer Anfallsfreiheit. Extratemporale Epilepsien sind hingegen sowohl in der prächirurgischen Diagnostik als auch in der operativen Behandlung meist anspruchsvoller und die Resultate waren lange Zeit weniger gut. Neue diagnostische Entwicklungen als auch verfeinerte operative Techniken führten in den letzten Jahren zu besseren Operationsergebnissen. In diesem Artikel werden sowohl die diagnostischen Schritte als auch die Operationsergebnisse besprochen.
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Louise Draven Rudyanto, Dansen Frans. "Pengaruh Kualitas Tidur Terhadap Kejadian Kejang Pada Pasien Epilepsi". Jurnal Ilmiah Kesehatan Sandi Husada 12, nr 2 (31.12.2020): 897–901. http://dx.doi.org/10.35816/jiskh.v12i2.425.
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Latar Belakang : Epilepsi adalah kondisi gangguan neurologik yang paling sering ditemui. Pada negara berkembang, insidensi epilepsi lebih tinggi dari negara maju. Kejadian kejang pada epilepsi dapat dikurangi dengan pengobatan yang teratur akan tetapi tidak sedikit juga yang mengalami kejadian kejang berulang, hal ini dapat dipengaruhi beberapa faktor selain pengobatan yang tidak teratur. Salah satu faktornya adalah pengaruh dari kualitas tidur. Tujuan : Mengetahui lebih lanjut pengaruh kualitas tidur terhadap kejadian kejang pada epilepsy. Metode : Menggunakan studi literatur dari beberapa jurnal nasional dan internasional. Kesimpulan : Terdapat pengaruh kualitas tidur terhadap kejadian kejang pada pasien epilepsi.
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Baena, R. A., I. Mesián, L. Mendoza i Y. Lázaro. "Mood disorder in epilepsy: A case report". European Psychiatry 33, S1 (marzec 2016): S337. http://dx.doi.org/10.1016/j.eurpsy.2016.01.1177.
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IntroductionA lot of studies have described that up to 50% of patients with epilepsy develop psychiatric disorders: depression, anxiety and psychotic symptoms. We can classify these symptoms according to how they relate in time to seizure occurrence, i.e. pre-ictal/prodromal, ictal, post-ictal or inter-ictal. In this case, we have a 76 years old woman that develops a maniac-episode previously that she has an episode.ObjectivesMake a review about the prevalence, risk factors of psychiatric problem in epilepsy (biological, psychosocial and iatrogenic) and report of clinical case.MethodsReview the bi-directional associations between epilepsy and bipolar disorder (epidemiological links, evidence for shared etiology, and the impact of these disorders) with a integrated clinical approach.ResultsTheoretically, epilepsy and bipolar disorder share an important number of clinical and neurobiological features. Classic neuropsychiatric literature focused on major depression with data on bipolar disorder remains limited. However, actually there are many evidences that mood instability, mixed irritability even mania is not uncommon in patients with epilepsy.ConclusionsIt is important develop more sensitive and specific screening instruments to identify mood disorder in epilepsy's patients. Future research becomes decisive for a better understanding of the similarities between epilepsy and BD, and the treatment of both.Disclosure of interestThe authors have not supplied their declaration of competing interest.