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Vörös, K. "Book review". Acta Veterinaria Hungarica 51, nr 4 (1.10.2003): 563. http://dx.doi.org/10.1556/avet.51.2003.4.14.
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Hedlund, C. and Taboada, J.: Clinical Atlas of Ear, Nose and Throat Diseases in Small Animals (Farbatlas der Hals-Nasen-Ohren-Erkrankungen bei Kleintieren). Schlütersche Verlag und Druckerei. Hannover, 2002. 208 pages, 353 colour pictures, radiographs and 64 drawings in hard leather cover.
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Sótonyi, P., i G. Bodó. "Book reviews". Acta Veterinaria Hungarica 51, nr 2 (1.03.2003): 245–47. http://dx.doi.org/10.1556/avet.51.2003.2.13.
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Klaus-Dieter Budras, Patrick H. McCarthy, Wolfgang Fricke, Renate Richter: Anatomy of the Dog. An Illustrated Text. 4th edition with Aaron Horowitz and Rolf Berg. Schlütersche GmbH & Co. KG Verlag und Druckerei, Hannover, Germany. 222 pages, 71 large-sized colour plates including several illustrations, radiographs, drawings and photographs. 9¾ × 13½", hardcover. ISBN 3-87706-619-4. Price: Ł54 / € 86. Kees J. Dik: Atlas of Diagnostic Radiology of the Horse - Diseases of the Front and Hind Limbs. Second extended and revised edition, Schlütersche, Hannover, 2002. 300 pages with 702 radiographs, 82 drawings. 9¾ ×13½", hardcover. ISBN 3-87706-651-8. Price:€ 144 / USD 179.5 / £ 89.
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Seidel Menchi, Silvana. "Erasmus as Arminius – Basel as the Anti-Rome? Closed and Open Circles of Humanist Communication". Archiv für Reformationsgeschichte - Archive for Reformation History 99, nr 1 (1.12.2008): 66–96. http://dx.doi.org/10.14315/arg-2008-0105.
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ZUSAMMENFASSUNG In den Werken des Erasmus, insbesondere in seinem Epistolar und in seiner Kontroverse mit Hutten, finden sich verstreute Zeugnisse, die die Vorstellung eines zweifachen Kommunikationskreislaufs stützen - eines offenen, die bestehenden Machtverhältnisse bei der Übermittlung von Nachrichten respektierenden Diskussionszusammenhangs sowie eines geschlossenen, in dem beißende Ironie und scharfe Attacken gegen die Potentaten und die Kirche zirkulierten. Der vorliegende Beitrag will dieses doppelte Kommunikationssystem aufdecken. Dabei wird sowohl der offene, sich der Druckerzeugnisse bedienende Kommunikationsverlauf veranschaulicht als auch die vertrauliche Kommunikation, die in mündlicher Form, in kleinen Gruppen und unter Humanisten mit gemeinsamem schichtspezifischen und kulturellen Hintergrund stattfand. Die Hauptthese ist, daß Elemente der vertraulichen Kommunikation durch die Untersuchung der den gedruckten Werken der Humanisten beigefügten Illustrationen sowie durch Zusammenschau von Bild- und Wortquellen sichtbar gemacht werden können. Der Beitrag untersucht insbesondere die von Ambrosius Holbein stammenden Kupferstiche der Titelseiten einiger Werke aus der Druckerei des Johannes Froben in Basel und die damals kursierenden Schriften des Erasmus (u.|a. den Dialog „Iulius exclusus e coelis“). Auch die berühmte, Hans Holbein d.|J. zugeschriebene Flugschrift „Hercules Germanicus“ von 1522 erlaubt es, den Übergang von der mündlichen zur bildlichen Kommunikation nachzuvollziehen und den in der Nachricht enthaltenen ironisch-esoterischen Charakter beispielhaft zu erläutern
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Krijnsen, C. "Handbuch der Ökumenik, Band III/2. Im Auftrag des J.-A. Möhler-Instituts herausgegeven von Hans Jörg Urban und Harald Wagner. Paderborn, Verlag Bonifatius-Druckerei, 1987. 23½ x 12, 344 S., DM 48." Het Christelijk Oosten 40, nr 3 (12.11.1988): 219. http://dx.doi.org/10.1163/29497663-04003006.
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Krijnsen, C. "Handbuch der Ökumenik, Band III/1. Im Auftrag des J.-A. Möhler-Instituts herausgegeben von Hans Jörg Urban und Harald Wagner. Paderborn, Verlag Bonifatius-Druckerei, 1987. 23½ x 15, 267 S., DM 36." Het Christelijk Oosten 40, nr 2 (12.11.1988): 144. http://dx.doi.org/10.1163/29497663-04002010.
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Frisk, Matleena. "Druckerin perusesitys tutustuttaa ehkäisyvälineisiin teknologian historiana". Tekniikan Waiheita 39, nr 4 (14.03.2022): 39–40. http://dx.doi.org/10.33355/tw.111277.
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Rusterholz, Caroline. "Donna J. Drucker, Contraception, A Concise History". European Journal for the History of Medicine and Health 78, nr 1 (10.03.2021): 222–25. http://dx.doi.org/10.1163/26667711-78010006.
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Mas, Catherine. "Contraception: A Concise History by Donna J. Drucker". Technology and Culture 61, nr 3 (2020): 949–51. http://dx.doi.org/10.1353/tech.2020.0088.
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Pitzulo, Carrie. "Donna J. Drucker, The Classification of Sex: Alfred Kinsey and the Organization of Knowledge". Cultural History 5, nr 2 (październik 2016): 226–28. http://dx.doi.org/10.3366/cult.2016.0129.
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Singer, Jane B. "Gary Gumpert/Susan J. Drucker (eds.): Take Me Out to the Ballgame: Communicating Baseball". Publizistik 48, nr 2 (czerwiec 2003): 243–44. http://dx.doi.org/10.1007/s11616-003-0072-y.
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Surma, Mateusz, Izabela Ducin, Maciej Sypek, Przemyslaw Zagrajek i Agnieszka Siemion. "Optimization of THz diffractive optical elements thickness". Photonics Letters of Poland 10, nr 4 (31.12.2018): 115. http://dx.doi.org/10.4302/plp.v10i4.873.
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Diffractive optical elements (DOEs) are strictly related to the design wavelength due to the fact that they must introduce particular phase delay of the wavefront propagating through the structure. Mostly the attenuation of the material is not taken into account. In this article we propose to optimize thickness of the DOE by reducing introduced phase retardation but also attenuation. The efficiency of DOEs is determined by the method of coding phase distribution and can be easily measured by using diffraction orders of corresponding diffraction grating. Here, we analyze binary phase diffraction gratings with assumed attenuation. Full Text: PDF ReferencesJ.-L. Coutaz, Optoélectronique térahertz (Les Ulis CEDEX A, France, EDP Sciences 2012). DirectLink D. Headland, Y. Monnai, D. Abbott, C. Fumeaux,and W. Withayachumnankul, "Tutorial: Terahertz beamforming, from concepts to realizations", APL Photonics 3, 5 (2018). CrossRef S. F. Busch, M. Weidenbach, M. Frey, F. Schäfer, T. Probst, nd M. Koch, "A 3D-Printable Polymer-Metal Soft-Magnetic Functional Composite—Development and Characterization", Journal of Infrared, Millimeter, and Terahertz Waves 35, 12 (2014) CrossRef A. Siemion, P. Kostrowiecki-Lopata, A. Pindur, P. Zagrajek, M. Sypek, "Paper on Designing Costless THz Paper Optics", Advances in Materials Science and Engineering 2016, 9615698 (2016). CrossRef A. Siemion, A. Siemion, M. Makowski, J. Suszek, J. Bomba, A. Czerwinski, F. Garet, J.-L. Coutaz, and M. Sypek, "Diffractive paper lens for terahertz optics", Opt. Lett. 37, 4320–4322 (2012). CrossRef J.-L. Coutaz, F. Garet, E. Bonnet, A. V. Tishchenko, O. Parriaux, and M. Nazarov, "Grating Diffraction Effects in the THz Domain", Acta Phys. Pol. A 107, 26-37 (2005). CrossRef M. S. Heimbeck, P. J. Reardon, J. Callahan, and H. O. Everitt, "Transmissive quasi-optical Ronchi phase grating for terahertz frequencies", Opt. Lett. 35, 21 (2010). CrossRef D. Li, S. Shu, F. Li, G. Ma, Y. Dai, and H. Ma, "Anomalous transmission of terahertz wave through one-dimensional lamellar metallic grating", Opt. Commun. 284, 10-11 (2011). CrossRef X. Li, and S. F. Yu, "Diffraction Characteristics of Concentric Circular Metal Grating Operating at Terahertz Regime", IEEE Journal of Quantum Electronics 46, 6 (2010). CrossRef B. Nöhammer, C. David, J. Gobrecht, and H. P. Herzig, "Optimized staircase profiles for diffractive optical devices made from absorbing materials", Opt. Lett. 28(13), 1087-1089 (2003). CrossRef V. Deuter, M. Grochowicz, S. Brose, J. Biller, S. Danylyuk, T. Taubner, D. Grutzmacher, and L. Juschkin, "Holographic masks for computational proximity lithography with EUV radiation", International Conference on Extreme Ultraviolet Lithography 2018 10809, 108091A (2018). CrossRef J. W. Goodman, Introduction to Fourier optics (Greenwood Village, USA, Roberts & Company Publishers 2005). DirectLink W. B. Veldkamp, "Optimized staircase profiles for diffractive optical devices made from absorbing materials", Appl. Opt. 21(17), 3209-3212W (1982). CrossRef W. B. Veldkamp, and C. J. Kastner, "Beam profile shaping for laser radars that use detector arrays", Appl. Opt. 21(2), 345-356 (1982). CrossRef https://www.mcortechnologies.com/de/3d-drucker/mcor-iris/ DirectLinkM. Sypek, M. Makowski, E. Hérault, A. Siemion, A. Siemion, J. Suszek, F. Garet, and J.-L. Coutaz, "Highly efficient broadband double-sided Fresnel lens for THz range", Opt. Lett. 37, 12 (2012). CrossRef
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Pettit, Michael. "The Classification of Sex: Alfred Kinsey and the Organization of Knowledge by Donna J. Drucker". Technology and Culture 57, nr 1 (2016): 271–72. http://dx.doi.org/10.1353/tech.2016.0019.
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Fishman, Donald. "Regulating Social Media: Legal and Ethical Considerations, Susan J. Drucker and Gary Gumpert (eds) (2013)". Explorations in Media Ecology 17, nr 4 (1.12.2018): 513–15. http://dx.doi.org/10.1386/eme.17.4.513_5.
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Rocha, Leon Antonio. "The Classification of Sex: Alfred Kinsey and the Organization of Knowledge - by Donna J. Drucker". Centaurus 57, nr 2 (maj 2015): 123–25. http://dx.doi.org/10.1111/1600-0498.12090.
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Ding, Xiang, Na Chen, Fan Zhang i Guangqing Zhang. "Evolution of Strength Parameters for Sandstone Specimens during Triaxial Compression Tests". Advances in Civil Engineering 2021 (18.06.2021): 1–11. http://dx.doi.org/10.1155/2021/8856743.
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Despite the lack of test data of the coefficient of pressure sensitivity α and the shearing cohesion k, the Drucker–Prager criterion is commonly applied for numerical analyses of geotechnical engineering. To bridge the gap between the wide application and insufficient knowledge of strength parameters of the Drucker–Prager criterion, this study presents experimentally calibrated strength parameters of this criterion for the first time. This paper proposes a new method to measure α and k in the Drucker–Prager criterion. The square root of the second invariant of the deviatoric stress tensor J 2 is linearly fitted with the first invariant of the stress tensor I 1 in the stress space. The parameters φ and c in the Mohr–Coulomb criterion and α and k in the Drucker–Prager criterion are calibrated to the same set of triaxial compression tests of sandstones. With these testing results, five pairs of conversion formulae (which are most commonly used in the literature) are examined and the most appropriate pair of conversion formulae is identified. With parameters indicating cohesive strength (c and k) and parameters indicating frictional strength ( φ and α ), the evolutions of different strength components are compared with those in the cohesion-weakening friction-strengthening model. With an increase in plastic deformation, the cohesive strength parameters c and k firstly increase to a peak value and then decrease. The frictional strength parameters φ and α gradually increase at a decreasing rate after the initial yield point.
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Marigo, Jean-Jacques, i Kyrylo Kazymyrenko. "A micromechanical inspired model for the coupled to damage elasto-plastic behavior of geomaterials under compression". Mechanics & Industry 20, nr 1 (2019): 105. http://dx.doi.org/10.1051/meca/2018043.
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We propose an elasto-plastic model coupled with damage for the behavior of geomaterials in compression. The model is based on the properties, shown in [S. Andrieux, et al., Un modèle de matériau microfissuré pour les bétons et les roches, J. Mécanique Théorique Appliquée 5 (1986) 471?513], of microcracked materials when the microcracks are closed with a friction between their lips. That leads to a macroscopic model coupling damage and plasticity where the plasticity yield criterion is of the Drucker–Prager type with kinematical hardening. Adopting an associative flow rule for the plasticity and a standard energetic criterion for damage, the properties of such a model are illustrated in a triaxial test with a fixed confining pressure.
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Nikitin, Grigorii M., i Elena A. Nikitina. "Information society and virtual (distance) education." Pedagogy: history, prospects 3, nr 4 (29.08.2020): 25–36. http://dx.doi.org/10.17748/2686-9969-2020-3-4-25-36.
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New communication and information technologies are becoming the main force of the “new industrial revolution, which multiplies the capabilities of human intelligence”. The idea of an information society was formulated in the late 1960s – early 1970s. The term “information society” was coined by Yuri Hayashi, professor at the Tokyo Institute of Technology. Researchers and developers of the information society theory are: M. Castells, F. Webster, E. Giddens, J. Habermas, D. Martin, D. Bell, G. Molitor, O. Toffler, Z. Brzezinski, A. King, D. Nesbit, A. Touraine, P. Drucker, M. McLuhan. The term “information society” reveals the objective process of society becoming gradually aware of the importance of information as some independent fundamental entity (along with energy and matter) and its transformation into a real productive force.
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문근찬. "Extending the Corporate Social Responsibilities According to P. F. Drucker and J. Rawls - Focused on Unemployment Problem -". Review of Business History 26, nr 2 (czerwiec 2011): 117–42. http://dx.doi.org/10.22629/kabh.2011.26.2.005.
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Boyle, Kris. "Book Review: Regulating Social Media: Legal and Ethical Considerations, edited by Susan J. Drucker and Gary Gumpert". Journalism & Mass Communication Quarterly 91, nr 2 (5.05.2014): 384–86. http://dx.doi.org/10.1177/1077699014531194.
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Tabbara, Tarik. "Susan J. Drucker / Gary Gumpert (Hrsg.): Real Law@Virtual Space. Communication Regulation in Cyberspace, Cresskill: Hampton Press 1999". Medien & Kommunikationswissenschaft 49, nr 4 (2001): 565–67. http://dx.doi.org/10.5771/1615-634x-2001-4-565.
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Aronis, Carolin. "Communication and the Baseball Stadium: Community, Commodification, Fanship, and Memory, Dale Herbeck and Susan J. Drucker (eds) (2017)". Explorations in Media Ecology 17, nr 4 (1.12.2018): 515–18. http://dx.doi.org/10.1386/eme.17.4.515_5.
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Schwartz, Michael. "Drucker's communitarian vision and its implications for business ethics". Business Ethics: A European Review 13, nr 4 (październik 2004): 288–301. http://dx.doi.org/10.1111/j.1467-8608.2004.00371.x.
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Prado Matamoros, Andrea Michelle, Karla Gisella Velásquez Paccha i Walter Adalberto González García. "TRATAMIENTO NUTRICIONAL DE LA DIABETES TIPO II Y LA OBESIDAD". Universidad Ciencia y Tecnología 24, nr 106 (16.11.2020): 109–18. http://dx.doi.org/10.47460/uct.v24i106.403.
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La obesidad y la diabetes mellitus tipo II (DMT2) han sido declaradas pandemias del nuevo siglo, en virtud de su acelerado crecimiento y presencia en la población mundial. Sin embargo, el enfoque empleado en los tratamientos de estas condiciones ha radicado en la atención farmacológica de las comorbilidades asociadas, sin conseguir efectos positivos en la enfermedad en el largo plazo. En tal sentido, la investigación tuvo como objetivo determinar los parámetros básicos de atención de la obesidad y la DMT2, a través de la atención nutricional no farmacológica mediante una revisión bibliográfica en bases de datos atendiendo el contenido científico de cada estudio analizado. La evidencia científica es consistente es señalar que un tipo de alimentación con unaporte bajo en grasa, contenido moderadamente alto en proteínas, hidratos de carbono de bajo índice glucémico es adecuada para mantener y/o restablecer las condiciones de salud en este tipo de paciente.
Palabras Clave: Diabetes, Obesidad, Diabesidad, Nutrición.
Referencias
[1]M. Mangas, A. Martínez y P. García, «“Tratamiento Farmacológico de la Diabesidad”,» Nutr. Clín. Med, vol. VI, nº 1, pp. 34-4, 2012.
[2]L. Altamiro, M. Vásquez, G. Cordero, R. Álvarez, R. Añez, J. Rojas y V. Bermúdez, «Prevalencia de la diabetes mellitus tipo 2 y sus factores de riesgo en individuos adultos de la ciudad de Cuenca- Ecuador,» Avances en Biomedicina, vol. 6, nº 1, pp. 10-21, 2017.
[3]A. Forero, J. Hernández, S. Rodríguez, J. Romero, G. Morales y G. Ramírez, «La alimentación para pacientes con diabetes mellitus de tipo 2 en tres hospitalespúblicos de Cundinamarca, Colombia,» Biomédica, nº38, pp. 355-362, 2018.
[4]S. Durán, E. Carrasco y M. Araya, «Alimentación y diabetes,» Nutrición Hospitalaría, vol. 27, nº 4, pp. 1031-1036, 2012.
[5]J. Hernandez, «Recomendaciones para el tratamiento médico de la obesidad exógena en el nivel primario de atención,» Rev cuba med gen integr, vol. 34, nº 3, pp. 123-144, 2018.
[6]M. Acebo, «Obesidad y Salud: ¿En realidad existe el paciente obeso metabólicamente sano?,» Respyn, vol. 16, nº 2, p. 44–55, 2017.
[7]T. Suarez, J. Sandoval, M. Galván, G. López, A.Olivo, A. J y M. González, «Nutracéuticos: usos potenciales en el tratamiento de la diabetes,» Educacióny Salud Boletín Científico de Ciencias de la Salud del ICSa, vol. 6, nº 12, p. doi: https://doi.org/10.29057/icsa.v6i12.3101, 2018.
[8]R. Orellana, E. Salinas, D. Sánchez, J. Guajardo, E. Díaz y F. Rodríguez, «Tratamiento farmacológico de la diabetes mellitus tipo 2 dirigido a pacientes con sobrepeso y obesidad,» Medicina Interna México, vol. 35, nº4, pp. 525-536, 2019.
[9]O. Pereira, «Diabesidad: una epidemia del siglo XXI,» Medisan , vol. 16, nº 2, pp. 295-299, 2012.
[10]S. Andino, «Evolución de la diabetes mellitus tipo 2 en pacientes obesos mórbidos después del by pass gástrico. Tesis para la obtención del título de posgrado de Doctor en Medicina,» Universidad Católica de Córdoba , Córdoba- Argentina , 2016.
[11]A. Muñoz, M. Jiménez, R. Mora, A. Hidalgo y D. Montoya, «Glucosa: amiga o enemiga,» de Diabetes mellitus: el reto a vencer, vol. 44, México, EditorialesFT, S. A., 2013, pp. 9-24.
[12]H. Bays, L. Mandarino y R. DeFronzzo, «Role of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type 2 diabetes mellitus: peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approach,» J Clin Endocrinol Metab, vol.89, nº 2, pp. 463-478, 2014.
[13]C. Quintanilla y S. Zúñiga, «El efecto incretina y su participación en la diabetes mellitus tipo 2,» Rev Med Inst Mex Seguro Soc, vol. 48, nº 5, pp. 509-520, 2013.
[14]L. Baggio y D. Drucker, «Biology of incretins: GLP-1 and GIP,» Gastroenterology, vol. 132, nº 6, pp. 2131-2157, 2014.
[15]Z. Cabrera y J. Díaz, «Sobrepeso - obesidad como factor de riesgo a la nefropatía en pacientes diabéticos del Hospital Víctor Lazarte Echegaray.2015,» Cientifi-k , vol. 5, nº 2, pp. 155-201, 2017.
[16]F. Abbasi, J. Chu, C. Lamendola, T. McLaughlin, J. Hayden, G. Reaven y et al, «Discrimination between obesity and insulin resistance in the relationship withadiponectin,» Diabetes, vol. 53, nº 3, pp. 585-590, 2014.
[17]M. Navarro, I. Jáuregui y G. Herrero, «Trastornos de la conducta alimentaria y diabetes mellitus: Tratamiento nutricional,» vol. 5, nº 9, pp. 914-1066, 2020.
[18]A. Forero, J. Hernández, M. Rodríguez, J. Romero, G. Morales y G. Ramirez, «“La alimentación para pacientes con diabetes mellitus de tipo 2 en tres hospitales públicos de Cundinamarca, Colombia,» Biomédica, vol. 38, pp. 355-62, 2018.
[19]S. Ramón y G. Medina, «Conocimientos, actitudes y prácticas nutricionales en diabéticos tipo 2 que integran los clubes de diabéticos urbanos, Cuenca, 2015,» Recimundo, vol. 2, pp. 595-610, 2018.
[20]A. Prado, M. Mazacón y T. Estrada, «Aspectos nutricionales en la atención del paciente con diabetes,» Universidad, Ciencia y Tecnología, nº 02, pp. 132-139,2019.
[21]D. Cárdenas, C. Bermúdez, S. Echeverri, A. Pérez, M. Puentes, L. López, M. Correia, J. Ochoa, A. Ferreira, M. Texeira, D. Arenas, H. Arenas, M. León y D. Rodríguez, «Declaración de Cartagena. declaración internacional sobre el derecho al cuidado nutricional y la lucha contra la malnutrición Cartagena,» Nutr Hosp, vol. 36, nº 4, pp. 974-980, 2019.
[22]M. Manrique, M. de la Maza, F. Carrasco, M. Moreno, C. Albala, J. García, J. Díaz y C. Liberman, «Diagnóstico, evaluación y tratamiento no farmacológicodel paciente con sobrepeso u obesidad,» Rev Méd Chile, vol. 137, pp. 963-971, 2009.
[23]A. Laparra, «Revisión sistemática y metaanálisis de los diferentes enfoques dietéticos para el tratamiento de la diabetes tipo 2: Lectura Crítica DARE,» Revista española de nutrición humana y dietética , vol. 21, nº 4, pp. 393-396, 2017.
[24]F. Represa, «Comorbilidad, control metabólico y calidad de vida en los pacientes diabéticos tipo 2,» Biblioteca Lascasas, 2016.
[25]P. Riobó Serván, «“Pautas dietéticas en la diabetes y en la obesidad”,» Nutr. Hosp., vol. 35, nº 4, pp. 109-115, 2018.
[26]M. Hernández, M. Batle, B. Martínez, R. San Cristobal, S. Pérez, S. Navas y J. Martínez, «Cambios alimentarios y de estilo de vida como estrategia en la prevención del síndrome metabólico y la diabetes mellitus tipo 2: hitos y perspectivas,» Anales Sis San Navarra , vol. 39, nº 2, pp. 269-289, 2016.
[27]R. Li, S. QU , P. Zhang, S. Chattopadhyay , E. Gregg , A. Albright , D. Hopkins y N. Pronk, «Economic evaluation of combined diet and physical activitypromotion programs to prevent type 2 diabetes among persons at increased risk: a systematic review for the Community Preventive Services,» Ann Intern Med, vol. 163, nº 6, pp. 452-460, 2016.
[28]J. López, Envejecimiento y nutrición. Intervención nutricional en pacientes diabéticos, Madrid: Sociedad Española de Geriatría y Gerontología , 2015.
[29]I. Brajkovich, M. Izquierdo, R. Nieto y M. Cordero , «Tratamiento no farmacológico: aspectos nutricionales, estilo de vida y actividad física. Cirugía bariátrica,»Revista Venezolana de Endocrinología y Metabolismo, vol. 1, nº 1, pp. 47-57, 2012.
[30]O. González, «Manejo nutricional en la diabetes mellitus tipo 2 y obesidad,» Revista Médica, vol. 4, nº1, pp. 22-31, 2014.
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Joynt, Chase, i Emmett Harsin Drager. "Condition Verified: On Photography, Trans Visibility, and Legacies of the Clinic". Arts 8, nr 4 (13.11.2019): 150. http://dx.doi.org/10.3390/arts8040150.
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We approach this paper with a shared investment in historical and contemporary representations of trans and gender non-conforming people, and our individual research in the archives of early US Gender Clinics. Together, we consider what is at stake—or what might be possible—when we connect legacies of photography used as diagnostic tools in gender clinics with snapshots of early, community-based gatherings, and the presence of trans people in contemporary art. From the archives of Robert J. Stoller and photos of Casa Susanna, to the collaborative photography of Zackary Drucker and Amos Mac, and the biometric data art-theory experiments of Zach Blas, we engage a series of image-based projects, which animate underlying questions and socio-political debates about the politics of visuality, and visibility’s impact on trans and gender non-conforming people. Moreover, we argue that rhetorical strategies of proof—from conditions verified in clinics to shared existence through photography—are tethered to, and thus trapped by, the logics and discipline of legibility and re-institutionalization.
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Pazmino Gavilanez, Washington Enrique, Veronica Alexandra Merchan Jacome i David Enrique Zambrano Moreira. "Strategic planning process as a management tool in a changing financial and business environment". Universidad Ciencia y Tecnología 25, nr 111 (4.12.2021): 5–13. http://dx.doi.org/10.47460/uct.v25i111.510.
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Strategic planning has become, for decades, a fundamental element and competitive value of the management of companies of all sizes, through the application of appropriate tools to establish the situation of the organization and its perspectives. Defining a strategy enables organizations, both public and private, to clearly define the type of activity they perform and to address the challenges of their external and internal environment, through plans oriented toward productivity, efficiency, and effectiveness. Through a bibliographic and documentary review, this article aims to establish the state of the question about strategic planning, especially in the context of the complexity of today's world that organizations must face, so affected by various situations such as economic contraction, the advancement of technologies, the environmental crisis, the redistribution of global power, the effects of the pandemic and new international tensions. It is concluded that strategic planning constitutes a specific competitive advantage for companies in all situations, including problems such as the current one related to the COVID 19 pandemic.
Keywords: Strategic planning, companies, business environment.
References
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Borzenko, Olena. "Imperatives of development of post-socialist countries financial markets". University Economic Bulletin, nr 43 (20.11.2019): 80–88. http://dx.doi.org/10.31470/2306-546x-2019-43-80-88.
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The relevance of the article in the analysis of the modern geopolitical space in which there are dramatic changes that qualitatively alter the disposition of post-socialist countries and regions of the world under the influence of scientific, technological, information, organizational and social process. The process of forming regulatory mechanisms for the functioning of the financial markets of the post-Soviet countries is linked to the transformation processes of global monetary and financial relations management. In modern conditions, the national financial market cannot be separated from the processes occurring in the world economy. In the last decades theoretical and practical problems of geoeconomics and global science have been investigated in the works of foreign scientists: L. Abalkin, M. Alle, U. Anderson, A. Anikina, J. Ackerloff, J. Arriga, D. Bell, W. Beck, Z. Brzezinski, I. Wallerstein, L. Galitz, J. Gelbraith, E. Giddens, M. Golovnin, P. Drucker, A. Kavkin, M. Castels, D. Keynes, L. Krasavina, V. Kruglov and others. It is observed that in the process of interaction of various factors of development in the world markets, an appropriate market conjuncture is formed, which reflects changes in specific conditions of market functioning and supply and demand, related to the dynamics of prices for goods and profits of firms and based on the cyclical development of the world economy, reflecting the nature of a market economy. Research methods are based on general scientific principles and fundamental principles of economic theory, theories of international economic relations and financial globalization, evolving in the face of geo-economic changes. The development of post-socialist countries is characterized by significant differences in the rates of economic growth and stabilization of monetary and financial systems, which is caused by: first, a significant stratification of economies in terms of development; second, the disintegration processes in mutual trade and more successful integration into the global trading environment due to the accelerated liberalization of the foreign trade sector compared to the financial sector; third, the incompleteness of financial sector reforms and the low level of development of financial services markets, respectively, the inefficiency of financial integration; fourth, the monetary and financial systems of the countries of the region remain vulnerable to the external effects of the crisis. The most powerful post-socialist countries (Russia, Kazakhstan, Ukraine, Azerbaijan) make more effective use of the benefits of globalization in the sphere of integration into the world economy.
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Wasyliw, Christina. "Back to the basics: Peter Drucker fifty years later". Canadian Public Administration/Administration publique du Canada 47, nr 4 (grudzień 2004): 559–64. http://dx.doi.org/10.1111/j.1754-7121.2004.tb01195.x.
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Johann, Denise Adriana, Luis Felipe Dias Lopes, Sirlene Aparecida Takeda Bresciani, Claudete Correa dos Santos i Valéria Wisnieski Padilha. "PRODUÇÃO ACADÊMICA SOBRE INOVAÇÃO FRUGAL: UMA ANÁLISE BIBLIOMÉTRICA EM PERIÓDICOS INTERNACIONAIS NA ÚLTIMA DÉCADA". International Journal of Knowledge Engineering and Management 9, nr 25 (14.12.2021): 31–52. http://dx.doi.org/10.47916/ijkem-vol9n25-2020-83417.
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Objetivo: Analisar a produção científica na área de Inovação Frugal (IF), nas bases de dados Web of Science e Scopus (CAPES, 2021). Metodologia: A pesquisa é caracterizada como descritiva com abordagem quantitativa e aplicação da técnica bibliométrica. Assim, após definir a técnica e tema, a busca foi realizada nas bases WoS e Scopus por tópico, utilizando os termos “frugal innovation”, com intervalo de tempo de 2010 a 2020, resultando em 306 publicações na WoS e 396 na Scopus. Em seguida, os dados foram organizados na Planilha Excel e após, as publicações foram identificadas nas seguintes categorias: evolução temporal, áreas temáticas, publicações por países, autores e frequência de citações. Por fim, utilizou-se o software VOSViewer para a criação de mapas textuais e clusters de co-citação. Resultados: Destaca-se que a temática de Inovação Frugal vem crescendo em frequência de publicações, destacando-se o ano de 2020. Dentre os resultados, a Índia e Estados Unidos encontram-se entre os primeiros que mais publicam e em nona posição encontra-se o Brasil encontra-se em nona posição. Quanto a area, Gestão, Negócios e Contabilidade tem a primeira posição. Entre os anos de 201 a 2020, somando entre as bases, tem-se o total de 5.281 citações. Originalidade/Valor: O uso da técnica de bibliometria apresenta-se como uma ferramenta relevante para a disseminação do conhecimento científico e tecnológico, possibilitando aos pesquisadores a análise quantitativa, descritiva e prognóstica de publicações realizadas em uma determinada área da ciência. Além disso, este estudo contribui com a disseminação do conhecimento sobre a inovação frugal, que é necessária para países que buscam o desenvolvimento econômico a partir da diminuição do uso de recursos e atendendo uma maior quantidade de pessoas, que antes não tinham acesso a determinados mercados e produtos. Palavra-chave: Inovação, Inovação Frugal, Bibliometria. Baptista, R., Escaria, V.& Madruga, P. (2008). Entrepreneurship, regional development and job creation: the case of Portugal. Small Business Economics, 30(1),49-58. Bhatti, Y. A. (2012). What is Frugal, What is Innovation? Towards a Theory of Frugal Innovation. SSRN Electronic Journal, p. 1-45. Bouchery, Y.; Ghaffari, A.; Jemai, Z. & Fransoo, J. (2016). Sustainable transportation and order quantity: insights from multiobjective optimization. Flexible Services and Manufacturing Journal, 28 (3), 367-396. Crossan, M. M.; Apaydin, M. (2010). A multi‐ dimensional framework of organizational innovation: A systematic review of the literature. Journal of Management Studies, 47 (6), 1154-1191. Drucker, P. F. (2016). Inovação e Espírito Empreendedor: (entrepreneurship): práticas e princípios. tradução de: Carlos J. Malferrari. São Paulo: Cengage Learning. Elia, G.; Margherita, A.& Petti, C. (2016). An operational model to develop technology entrepreneurship EGO-system, International Journal of Innovation and Technology Management, 13 (5),164-182. Hair, J.F.; Tatham, R. L.; Anderson, R. E.& Black, W. C. (1998). Análise multivariada de dados. Tradução Adonai Schlup Sant’Anna e Anselmo Chaves Neto. 5. ed. Porto Alegre: Bookman. Hossain, M.; Simula, H.& Halme, M. (2016) Can Frugal go global? Diffusion patterns of frugal innovations. Technology in Society, 46, 132-139. Jiménez, D. J.; Costa, M. M. & Valle, R. S. (2014). Knowledge management practices for innovation: a multinational corporation‘s perspective. Journal of Knowledge Management, 18 (5), 905-918. Khan, R. (2016). How frugal innovation Promotes Social Sustainability. Sustainability, 8 (1034),1-29. Kunamaneni, S. (2019). Challenges in moving from incremental to radical low-cost innovation in emerging and transition countries: institutional perspectives based on rechargeable battery innovation in China and point-of-use water purification innovation in India. International Journal of Innovation Management, 23(03), 1-36. Leydesdorff, L.& Etzkowitz, H. (1998). The Triple Helix as a model for innovation studies. Science and Public Policy, 25(3), 195-203. Moustaghfir, K.& Schiuma, G. Knowledge, learning, and innovation: research and perspectives. Journal of Knowledge Management, 17(4), 495 – 510. Oliveira, J.& Moraes, K. (2016). Produção do conhecimento na universidade pública no brasil: tensões, tendências e desafios. Educação em Revista. Belo Horizonte, 32(4). Prabhu, J. (2017) Frugal innovation: doing more with less for more, Philosophical Transactions of the Royal Society A, 375 (2095), 375. Quandt, C. O.; Bezerra, C. A. & Ferraresi, A. A. (2015). Dimensions of organizational innovativeness and its impact on innovation performance: proposition and evaluation of a model. Gestão & Produção, 22(4), 873-886. Prahalad, C. K.& Hart, S. L. (2008). The fortune at the bottom of the pyramid. Estratégias e Negócios, Florianópolis, 1(2), 1-23. Radjou, N. & Prabhu, J. (2014). What frugal innovators do. Harvard Business Review, v. 10. Ramos‐Rodríguez, A. R & Ruíz‐Navarro, J. (2004). Changes in the intellectual structure of strategic management research: a bibliometric study of the Strategic Management Journal 1980-2000. Strategic Management Journal, 25, 981-1004. Rao, B. C. (2017). Advances in science and technology through frugality. IEEE Engineering Management Review, 45 (1), 32-38. Schumpeter, J. A. (1934). A Teoria do Desenvolvimento Econômico: Uma Investigação sobre Lucros, Capital, Crédito, Juros e o Ciclo de Negócios, Transaction Publishers, Cambridge. Schumpeter, J. A. (1982). Teoria do desenvolvimento econômico: uma investigação sobre lucros, capital, crédito, juro e o ciclo econômico. Abril Cultural. Simula, H.; Hossain, M. & Halme, M. (2015). Frugal and reverse innovations – Quo Vadis? Current Science, 109 (5), 1567-1572. Tiwari, R. & Herstatt, C. (2012). India-a lead market for frugal innovations? Extending the lead market theory to emerging economies. TIM/TUHH Working Paper, n. 67. Torres, T. Z.; Pierozzi, J. I.; Pereira, N. R. & CASTRO, A. de. Knowledge management and communication in Brazilian agricultural research: An integrated procedural approach. International Journal of Information Management. v. 31, p. 121-127. Weyrauch, T. & Herstatt, C. (2017). What is frugal innovation? Three defining criteria. Journal of Frugal Innovation, 2 (1). Zeschky, M.; Widenmayer, B. & Gassmann, O. (2011). Frugal Innovation in Emerging Markets. Research-Technology Management, 54(4), 38-45.
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Rocha Júnior, Fernando Soares, Vânia Meneghini da Rocha i Marcelo Macedo. "COMPARTILHAMENTO DE CONHECIMENTO EM UMA PEQUENA EMPRESA DE PRODUTOS ORTOPÉDICOS: ANÁLISE DAS PERCEPÇÕES DOS COLABORADORES". International Journal of Knowledge Engineering and Management 9, nr 25 (14.12.2021): 127–43. http://dx.doi.org/10.47916/ijkem-vol9n25-2020-81913.
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O objetivo central deste artigo é tentar compreender por meio da visão dos colaboradores de uma pequena empresa de produtos ortopédicos, as suas principais percepções, relacionadas ao compartilhamento de conhecimento organizacional. O método escolhido para a pesquisa é qualitativo com a tipologia qualitativa básica. Para a análise de resultados, foi utilizada a técnica de análise temática de Braun e Clarke. Os principais resultados encontrados demonstram que o compartilhamento de conhecimento na organização é realizado por intermédio da utilização das tecnologias de comunicações comuns ao público, assim como, com a realização frequente da técnica de brainstorming, conversas rápidas e outras estratégias para resolução de problemas conforme identificados nesta pesquisa. Referências Alavi, M., & Leidn, D. E. (2001). Knowledge management and knowledge management systems: Conceptual foundations and research issues. MIS Quarterly, 25, 107–136. Allameh, S. M.; Khozani, M. K.; Baniasadi, B. (2020) Consequences of knowledge processes in small businesses: the role of knowledge acquisition, dynamic capabilities, knowledge sharing and creativity. Int. J. Process Management and Benchmarking, Vol. 10, No. 1. Braun, V.; Clarke, V. (2012) Thematic analysis. In: Cooper, H. et al. (Eds.). APA handbook of research methods in psychology, v. 2, Research designs: Quantitative, qualitative, neuropsychological, and biological. Washington, DC: American Psychological Association, v. 2 p. 57-71. Creswell, J. W. (2007) Projeto de pesquisa: Métodos qualitativo, quantitativo e misto. 2. ed. Porto Alegre: Artmed. Cummings, J. (2003) Knowledge Sharing: A Review of the Literature. Washington D. C.: The World Bank Operations Evaluation Department. Dalkir, K. (2005) Knowledge Management in Theory and Practice. Oxford, UK: Elsevier. Drucker, P. F. (1993) Sociedade Pós-Capitalista. São Paulo: Pioneira. Gold H. A.; Malhotra, A; Segars, A, H.; (2001). Knowledge management: An Organizational Capabilities Perspective. Journal of Management Information Systems, 18 (1), 185-214. Gray, C. (2006). Absorptive capacity, knowledge management and innovation in entrepreneurial small firms. International Journal of Entrepreneurial Behavior & Research, 12 (6),345-360. Harel, R.; Schwartz, D.; Kaufmann, D. (2020) Sharing knowledge processes for promoting innovation in small businesses. European Journal of Innovation Management. ISO 30401:2018. (2018) International Organization For Standardization. Knowledge Management Systems – Requirements. Genebra: ISO. Kayas, O, G.; Wright, G. (2018) Knowledge Management and Organisational Culture. The Palgrave Handbook of Knowledge Management. ISBN 978-3-319-71434-9 (eBook). Merriam, S. B. (2009) Qualitative research: a guide to design and implementation. San Francisco: Jossey-Bass/Wiley, 2009. Morgan, G. (1980) Paradigms, metaphors, and puzzle solving in organization theory. Administrative Science Quarterly, v. 25, n. 4, p. 605-622. Na Ubon, A.; Kimble, C. (2002) Knowledge Management in Online Distance Education. Proceedings of the 3rd International Conference Networked Learning, University of Sheffield, UK, pp. 465-473. Ngah e Ibrahim (2010). The Effect of Knowledge Sharing on Organizational Performance in Small and Medium Enterprises. Santos, N.; Rados, G. J. V. (2020) Fundamentos teóricos de gestão do conhecimento. E-book. – 1. ed. – Florianópolis: Pandion, 114 p. Takeuchi, H.; Nonaka, I. (2008) Criação e dialética do conhecimento. In: Takeuchi, H.; Nonaka, I. Gestão do conhecimento. Porto Alegre: Bookman. Utami, Y.; Rofik, M.; Cahyaningtyas, N. W.; Darminto, D. P. (2021). Impact of Knowledge Sharing and Innovation on Small Business Performance. CISIS 2020: Complex, Intelligent and Software Intensive Systems pp 408-411.
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Savlov, Mikhail E. "Crucial differences between present service sector structures of Russia and Poland: changes and contribution to the economy". GEOGRAPHY, ENVIRONMENT, SUSTAINABILITY 13, nr 4 (31.12.2020): 140–47. http://dx.doi.org/10.24057/2071-9388-2019-155.
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During the period of planned economies in Russia and Poland, services were underestimated as a sector of economic activity. To some degree, this continues to be the case. In spite of the existence of market economies in Central and Eastern Europe for more than 25 years, Russia and Poland should be categorized differently in terms of economic and social development. Based on D. Bell’s and his followers’ (M. Castells, A. Toffler, J. Rifkin, P. Drucker) theory of post-industrial society and post-industrial economy, Poland can be classified as a post-industrial country, while Russia is still an industrial country in many aspects. This point of view is based on global statistics and cross-country comparisons. The following statistical data has been used as a source for this research: share of services in GDP by country, contribution (value added) of seven main types of services to the respective GDP of Russia, Poland and other selected countries, value added and governmental expenditures per capita of primary services in aforementioned economies. The main differences between the Russian and Polish service sectors are indicated. The cases of Russia and Poland are presented here to highlight the key common features of Central and Eastern European countries’ tertiary sectors.
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Stefanyshyn, Oksana, i Natalia Magas. "FORMING A SYSTEM OF VIEWS ON BUILDING THE CONCEPT OF AN EFFECTIVE MANAGER AS A MODERN LEADER". Innovative Solution in Modern Science 1, nr 61 (17.03.2024): 5. http://dx.doi.org/10.26886/2414-634x.1(61)2024.1.
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The article examines the aspects of forming the type of an effective manager. In connection with the emergence and frequent repetition in scientific and special literature, on the websites of educational organizations, and requests in the labor market for the concept of "effective manager", the existence of such a type of manager in classical scientific literature is clarified; the essence of the category "effectiveness" and the possibility of its application to a manager as a modern leader are clarified; the author's definition of "effective manager" is given; the characteristics of an effective manager presented in the works of Drucker P.F., Judith L.-J., Pearson B. and Thomas N. are analyzed. The article also analyzes (to a limited extent, within the framework of the article) the possibility of professional training in Ukraine through formal (in higher educational institutions) and informal education (business schools, training centers) in order to become an effective manager. The prospects for research lie in the field of continuing to study the characteristics and features of an effective manager in order to acquire and develop them in the system of education (formal and informal), self-education.Key words: modern requirements for managers, types of managers, effective manager, characteristics of an effective manager, professional training of a manager, informal education of a manager.
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Brown, R. "R. H. Gray, H. Drucker and M. J. Massey (eds). Toxicology of coal conversion processing. Wiley-Interscience, New York, 1988; 603 pp., $199, £70". Journal of Applied Toxicology 9, nr 1 (luty 1989): 70. http://dx.doi.org/10.1002/jat.2550090118.
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Popova, S. V. "SMALL BUSINESS: ILLUSIONS AND REALITY". Scientific Review: Theory and Practice 10, nr 10 (30.10.2020): 2301–12. http://dx.doi.org/10.35679/2226-0226-2020-10-10-2301-2312.
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In post-industrial society, there is an increase in the role of small business as an integral element of the reproduction process. The activities of small and medium-sized businesses in our country are carried out on the basis of the established global trends. Difficulties in the dynamics of this sphere are formed under the influence of increased concentration of production and consolidation of enterprises, which gives rise to a number of problems and contradictions. Considering small business as the most important component of the market economy, its role in solving the problems of creating a competitive environment and ensuring employment should be noted. The scientific literature on the problem under consideration shows the versatility in the authors’ views of the small business role in economic development. This problem is disclosed in sufficient detail in the works of foreign authors (M Weber, J. Gelbraith, P. Drucker, W. Sombart, R. Cantillon, R Coase, J. Keynes, K. Marx, A. Marshall, L. Mises, A. Smith, J. Schumpeter and others). In Russia, L. Abalkin, A. Anchishkin, K. Bazhenov, S. Witte, V. Inozemtsev, M. Lapusta, L. Slutsky, P. Stolypin, M. Tugan-Baranovsky, A. Chayanov and etc. considered this problem. The article reveals the role of small business in the Russian economy, as well as the problems and contradictions of its functioning. On the basis of a systematic analysis of the current trends, the problems, efficiency and significance of small business are identified. Research has shown that the role of small businesses is greatly exaggerated. Small business development acts as a factor in reducing unemployment. In the process of economic activity, a number of problems arise that the enterprises themselves cannot solve. A set of measures is required to support this activity and overcome the crisis. It is important that small and medium-sized enterprises can form their own accumulation fund, which can be used to adapt in the face of stagnation, which will increase the size of the labor force and labor productivity. The crisis of small and medium-sized businesses leads to a multiplier effect in the economy, which reduces the volume of GDP. As a result of the “concentration of capital” among large producers, smallscale production becomes unproductive and unprofitable. The opportunities for obtaining loans from small businesses are very limited. Modern high-tech productive equipment is not available to most. In many enterprises, there is no separation in order to save financial resources on wages. The social security of employees is low. The prosperity of any country in a post-industrial society depends on big business; small business is only an auxiliary sphere of activity. Relying on small business, it is impossible to improve the quality of life, to ensure economic growth and national security. The results of the study can be used in determining the strategic guidelines of economic policy and choosing development priorities.
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Wang, Jie, i Yi Xiao. "Some improvements on Sun–Chen’s one-parameter plasticity model for fibrous composites – Part I: Constitutive modelling for tension–compression asymmetry response". Journal of Composite Materials 51, nr 3 (28.07.2016): 405–18. http://dx.doi.org/10.1177/0021998316644853.
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Herein, a one-parameter plasticity model proposed by Sun and Chen [Sun CT and Chen JL. A simple flow rule for characterizing nonlinear behavior of fiber composites. J Compos Mater 1989; 23: 1009–1020] demonstrates features that make it highly attractive for characterizing non-linear responses of fibrous composites. However, a detailed exploitation of the model’s potential has been halted by unresolved problems that include tension–compression asymmetry in stress–strain curves, FEM implementation as well as optimal parameters determination, which are addressed in this investigation as well as proposed solutions are presented. The major focus in Part I of this three-part study was devoted to developing a simple model for predicting the tension–compression asymmetry in stress–strain curves for fibrous composites, which was based on Sun and Chen’s one-parameter plasticity model. A generalized Hill yield criterion was proposed from combinations of the Drucker–Prager yield criterion that considers the effect of hydrostatic pressure for isotropic materials and the Hill yield criterion suitable for anisotropic materials. By incorporating the yield strength-differential effect on the plastic flow rule in composite laminates, the one-parameter plasticity model was extended to a strength-differential effect-incorporated model. The improved model has been calibrated and validated by off-axis tension and compression tests on unidirectional carbon/epoxy (IM600/Q133) composite laminates. Results verified that the proposed model captured the complex tension–compression asymmetry in observed non-linear responses of stress–strain curves.
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Akhtar, Leena. "Donna J. Drucker. The Classification of Sex: Alfred Kinsey and the Organization of Knowledge. ix + 244 pp., illus., bibl., index. Pittsburgh: University of Pittsburgh Press, 2014. $30 (paper)." Isis 107, nr 1 (marzec 2016): 196–97. http://dx.doi.org/10.1086/686160.
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Zhang, Yuqing, Fan Gu, Bjorn Birgisson i Robert L. Lytton. "Viscoelasticplastic–Fracture Modeling of Asphalt Mixtures Under Monotonic and Repeated Loads". Transportation Research Record: Journal of the Transportation Research Board 2631, nr 1 (styczeń 2017): 20–29. http://dx.doi.org/10.3141/2631-03.
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Rutting and cracking occur simultaneously in asphalt mixtures as observed in the field and in the laboratory. Existing mechanical models have not properly addressed viscoelastic and viscoplastic deformation together with cracking attributable to model deficiencies, parameter calibration, and numerical inefficiency. This study developed viscoelasticplastic–fracture (VEPF) models for the characterization of viscoelasticity by Prony model and viscoplasticity by Perzyna’s flow rule with a generalized Drucker–Prager yield surface and a nonassociated plastic potential. Viscofracture damage was modeled by a viscoelastic Griffith criterion and a pseudo J-integral Paris’s law for crack initiation and propagation, respectively. The VEPF models were implemented in a finite element program by using a weak form partial differential equation modeling technique without the need for programming user-defined material subroutines. Model parameters were derived from fundamental material properties by using dynamic modulus, strength, and repeated load tests. Simulations indicated that the viscoelastic–viscoplastic–viscofracture characteristics were effectively modeled by the VEPF models for asphalt mixtures at different confinements and temperatures. An asphalt mixture under monotonic compressive loads exhibited a sequenced process including a pure viscoelastic deformation stage, a coupled viscoelastic–viscoplastic deformation stage, a viscoelastic–viscoplastic deformation coupled with a viscofracture initiation and a propagation stage, and then a viscoelastic–viscofracture rupture stage with saturated viscoplastic deformation. The asphalt mixture under repeated loads yielded an increasing viscoplastic strain at an increasing rate during the first half of the haversine load, while the increment of the viscoplastic strain (per load cycle) decreased with load cycles. The finite element program, which is based on a partial differential equation, effectively modeled the coupled viscoelastic–viscoplastic–viscofracture behaviors of the asphalt mixtures.
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Antoun, Ghadi, Jonathan Keow, Véronique D. Ram, Christina Thornton, Xin Wang i Ju-Yoon Yoon. "Scientific overview: CSCI-CITAC Annual General Meeting and Young Investigator’s Forum 2013". Clinical & Investigative Medicine 37, nr 4 (1.08.2014): 191. http://dx.doi.org/10.25011/cim.v37i4.21723.
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The 2013 joint Canadian Society of Clinician Investigators (CSCI)–Clinical Investigator Trainee Association of Canada/Association des cliniciens-chercheurs en formation du Canada (CITAC/ACCFC) annual general meeting(AGM) was held in Ottawa, September 2013. The symposium focused on “Applications of the ‘omics’ to Clinical Practice”, with presentations from Drs. William T. Gibson (University of British Columbia), Julie Ho (University of Manitoba) and David Hwang (University of Toronto), discussing topics of genome, proteome and the microbiome, respectively. Other highlights from the 2013 AGM include presentations by Dr. Salim Yusuf (McMaster University, 2013 CSCI-RCPSC Henry Friesen Award winner), Dr. Gary Lewis (University of Toronto, 2013 CSCI Distinguished Scientist Award winner) and Dr. Michael Taylor (University of Toronto, 2013 Joe Doupe Award winner). The CSCI/CITAC/Friends of CIHR Joint Symposium consisted of presentations from Drs. John Bell (University of Ottawa), Dan Drucker (University of Toronto) and Heather J. Dean (University of Manitoba). Finally, the meeting ended with the presentation “The Power of an Idea to Bring Ideas to Power” by Dr. Harvey V. Fineberg (President, U.S. Institute of Medicine), the winner of the 2013 Henry Friesen International Prize. Also presented at the conference was research by clinician investigator (CI) trainees from across Canada; ie., those enrolled in MD/MSc, MD/PhD or Clinician Investigator Program(CIP) programs. Canadian trainees’ research extended beyond the pillar of biomedical research, covering the spectrum between basic and clinical research, with a focus on the causes of significant morbidity and mortality for Canadians, including cancers, infectious diseases and other maladies. It is this research that we have summarized in this review.
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HALL, LESLEY A. "Donna J. Drucker, The Classification of Sex: Alfred Kinsey and the Organization of Knowledge (Pittsburgh: University of Pittsburgh Press, 2014), pp. xii + 244. IBSN 978-0-8229-6303-5 (pb)". Gender & History 29, nr 1 (10.03.2017): 224–25. http://dx.doi.org/10.1111/1468-0424.12266.
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Chorna, Maryna Vitaliivna, Tamila Borysivna Kushnir i Anatoly Mykhailovych Volosov. "FORMATION OF COMPETITIVE ADVANTAGES OF THE RETAIL ENTERPRISE". SCIENTIFIC BULLETIN OF POLISSIA, nr 3(15) (2018): 75–82. http://dx.doi.org/10.25140/2410-9576-2018-3(15)-75-82.
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Urgency of the research. Rapid changes require retail enterprises to create competitive advantages, strengthen their competitive potential, allowing them to stay on the crest during intensive growth of competition. Target setting. Formation of competitive advantages is one of the most important and complex tasks for each enterprise of domestic retail. Actual scientific researches and issues analysis. The theoretical and methodological basis of scientific research in the area of competitive advantage consists of the works of J. Schumpeter, M. Porter, M. Tracy, F. Viersem, H. Hamel, K. Prahal, P. Drucker, K. Kristensen, A. Matveev, S. Orlova, V.Tsarev, in the retail sector – S. Domínguez, A. Mazaraki, T. Melnyk. Uninvestigated parts of general matters defining. There is a need to deepen and improve the theoretical and methodological foundations of the system of forming competitive advantages of the retail enterprise on the basis of using the internal (existing competitive potential) and external (favorable factors of the external environment) sources. The research objective. The justification of the process of forming the competitive advantages of the retail enterprise, which is represented by a number of successive stages, deserves particular attention. The statement of basic materials. The system of formation of competitive advantages of a retail enterprise on the basis of the use of internal and external sources is considered in this article. The authors present a step-by-step sequence of forming competitive advantages, developed technology for the formation of competitive advantages, a comprehensive multi-criteria system for assessing the internal capabilities (competitive potential) of the retail enterprise. Conclusions. The presented system of formation of competitive advantages on the basis of use of internal and external sources provides practical tools for creating a set of actual competitive advantages of the retail enterprise in order to increase its competitiveness.
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Bakhur, Nadiia. "The influence of the institutional environment on development of investment activity in the agricultural sector of the economy". University Economic Bulletin, nr 46 (1.09.2020): 7–20. http://dx.doi.org/10.31470/2306-546x-2020-46-7-20.
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Relevance of the research topic. In the conditions of transformation, a special role in the formation of a favorable institutional environment for the intensification of investment activities in the agricultural sector is given to the state as an important institution for the organization of the process and its participants. Formulation of the problem. The relationship of investment activity with the processes of institutional transformation is still poorly studied in economic theory due to the novelty of this process and are systemic in nature. Here, a significant role is played, first of all, by the institutional features of the formation of a favorable investment environment in the conditions of deepening transformation and integration processes in the state. For the transformational economy, the system of economic property relations is an urgent problem, in particular, for the agricultural sector – it is land ownership. Analysis of recent research and publications. Many works of famous scientists are devoted to the issue of institutional theories of investment: A. Spithof [5, p. 330-331], J. Commons [3], W. Mitchell [15], J. Buchanan [4], W. Rostow [24], R. Coase [11], J. Ellull [27], R. Aron [18], J. Galbraith [30], J. Schumpeter [21], W. Favor [19], K. Eklund [7], A. Burley [6], G. Minz [6], I. Nadler [6], S. Chase [6], P. Drucker [26]. In Ukraine, scientific research of domestic scientists using the methodological tools of institutionalism A. Bykova, M. Kolesnik, T. Kosovo, N. Marenkov, A. Ivashina, V. Fedorenko is also presented. In the works of N. Marenkov [13], A. Bykova [1], O. Ivashina [1], M. Kolisnyk [9], M. Tugan-Baranovsky [20], the organization of the process of formation and development of non-market forms of economic interactions in conditions of transformation of social and economic relations. Selection of unexplored parts of the general problem. A special study of investment activity in the context of deepening transformation processes in the national economic system requires consideration of two aspects of this process: the need and principles of adaptation of investment institutions as carriers of another institutional tradition to the market environment; study of those positive institutional effects of direct investment, which contribute to the acceleration of institutional transformations, the adaptation of world "institutional standards" to national conditions. Setting the task, the purpose of the study. To study the theoretical and practical aspects of the relationship between structural and institutional transformation with the organization of the investment process in the agricultural sector. Method or methodology of the study. Institutionalism, as a scientific field, emerged at the turn of the XIX-XX centuries, as a trend that criticizes the methodological positions of the neoclassical school. Among the well-known representatives of this school are usually T. Veblen, J. Commons, W. Mitchell, D. Clark. At the same time, early institutionalism is sometimes considered as a precursor of Keynesianism [12, p. 28]. The methodological basis of the new institutionalism are the works of the classics of economic scientific thought. Presentation of the main material (results of work).The article examines the features of institutional support in the development of investment activitiesinthe agricultural sector. There is a need to take into account investment capacity in the methodology of analysis of investment potential,in the process of considering investment potential, from the point of view of the institutional approach. The processes of globalization are a catalyst in the search for ways to increase economic prosperity and an important prerequisite for this process is the investment potential. The possibility of using institutional theory in the development of investment activity is proved. A recommendation is given that the investment process and investment activities should be studied and considered in dynamics. Institutionalism focuses on a comprehensive study of economic systems. Theories of institutionalism related to investment are reduced to separate concepts of behavior of market participants and to the analysis of the investment climate. For the formation of international economic relations, an important element in determining the effectiveness of the global economy are approaches to institutional economics. The factor of high technology is an important factor in the formation of an economic institutional system. The subject of knowledge of institutional theory are institutions, and what are its advantages. The institute (as a subject of research), on the one hand, provides a broad view of the development of the economy and society, analysis of the economic system and society as a whole in interaction with other institutions, such as the state, and on the other - requires a deep and specific understanding institutions. From the point of view of representatives of institutionalism, institutions are a way of thinking and acting that is embodied in social customs, institutions, and rules. In the non-institutional direction, institutions are considered as factors influencing the decisions made by economic agents. The field of application of results. Directions for further development of the agricultural sector of the national economy depend on the investment policy that shapes the investment climate in the country and the ability of state institutions to implement it effectively. The investment process, as evidenced by world experience, is able to provide large-scale technical and technological renewal of the agricultural sector, which will result in increasing the competitiveness of agricultural production and ensuring sustainable social and economic development of the country. Conclusions according to the article.It should be noted that according to the methodology of the system approach, investment activity has all the hallmarks of a system that is developing dynamically and is influenced by external and internal institutional environment. The development of Ukraine's economy in the conditions of deepening transformation and integration processes is characterized by increasing influence of uncertainties and risks of the modern institutional environment in which investment activities are carried out not only by national but also foreign investors. Increasing the degree of uncertainty of the investment process in the transformation of the national social and economic system is due primarily to the fact that in the transition to market relations remain institutions and institutions inherited from the previous economic system, and market institutions are not yet formed or poorly functioning. Also, the development of the investment process is influenced by the constant change of the economic situation and the situation and competition in the investment capital market, the introduction of new technologies and methods of organizing the production process, and so on. Thus, institutionalism is a productive direction in the development of investment activities.
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Lukashuk, Maryna Anatoliivna. "СОЦІАЛЬНИЙ ДОСВІД ФОРМУВАННЯ ІННОВАЦІЙНОЇ КОНФІГУРАЦІЇ СУЧАСНИХ ЗНАНЬ". SOCIAL WORK ISSUES: PHILOSOPHY, PSYCHOLOGY, SOCIOLOGY, nr 2 (14) (2019): 100–107. http://dx.doi.org/10.25140/2412-1185-2019-2(14)-100-107.
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Urgency of the research. Today scholars are returning to the idea of the priority importance of science in society, a conscious desire of mankind to create a more humane configuration of its social relations is being formed. Target setting. The innovative configuration of the knowledge system should have an unconventional decentralized nature with the obligatory consideration of the peculiarities of the national semantic field and the type of culture. Actual scientific researches and issues analysis. The source study base of the research is made up of conceptual developments of such famous authors as L. Burrows, P. Bourdieu, D. Bell, M. Heidegger, P. Drucker, E. Durkheim, S. Zizek, J.-F. Lyotard, N. Luhmann, T. Parsons, O. Toffler, W. Eco and many other researchers. The works of such domestic scientists as V. Andrushchenko, L. Voznyuk, E. Gerasimova, S. Klepko, S. Kutsepal, V. Kusherets, M. Mulyar, D. Sviridenko, S. Terepischiy and others became the historiographic literature of the study. Uninvestigated parts of general matters defining. We can state that the process of comprehending the nature and meaning of innovative processes is in a constant dynamic state, therefore, despite the large-scale nature of the research carried out by famous domestic and foreign scientists, a set of questions remains unanswered. The research objective is to analyze the social experience of the formation of an innovative configuration of modern knowledge. The statement of basic materials. The new configuration of the modern knowledge system is a coordinated combination of opportunities, competencies, both material and invisible resources, values and aspirations for effective performance, which can be achieved in the future due to synergistic configurations. Conclusions. Having analyzed the configured synergistic effect of the innovative process of forming a modern knowledge system in Ukraine, as a complex social act that covers the analysis of many key competencies, taking into account the features of the national semantic field and the type of culture of the corresponding social production, as well as the possibility of obtaining effective social result from its practical application, the mechanism of their interaction was presented.
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Fong, Wei Chern Gavin, Sophie Leducq, Hywel Williams, Lucy Bradshaw i Kim Thomas. "P105 Reporting of concomitant and rescue topical therapies in eczema randomized controlled trials evaluating a systemic treatment: a scoping review". British Journal of Dermatology 191, Supplement_1 (28.06.2024): i65—i66. http://dx.doi.org/10.1093/bjd/ljae090.132.
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Abstract The landscape of atopic dermatitis (AD) treatment has witnessed an exponential increase in randomized controlled trials (RCTs) exploring systemic medications. These trials often incorporate topical therapies, such as topical corticosteroids and calcineurin inhibitors, either as permitted concomitant treatments (concomitant) or as rescue medications (rescue). Variable use of these topicals after randomization introduces potential bias as they may nullify or exaggerate treatment responses differentially. Factors such as treatment duration, application frequency and quantity further complicate the interpretation of trial results. Despite these complexities, there is a scarcity of literature addressing the systematic reporting of topical therapy details in AD clinical trials, particularly when evaluating systemic treatments. To address this gap, we reviewed current practices in reporting topical treatments in RCTs of AD systemic medication. Our primary objectives included determining the proportion of RCTs that clearly report the allowance or prohibition of concomitant and rescue topical treatments. Secondary outcomes involved examining the reporting of specific parameters for these topicals, such as type, potency, duration and application quantity. We used logistic regression models to explore the association between trial characteristics and clearly reporting the use of rescue therapy. We screened RCTs of AD systemic medication included in the living systematic review and network meta-analysis of AD systemic treatments by Drucker et al. (n = 83), spanning from inception to March 2023 (Drucker AM, Lam M, Elsawi R et al. Comparing binary efficacy outcomes for systemic immunomodulatory treatments for atopic dermatitis in a living systematic review and network meta-analysis. Br J Dermatol 2024; 190: 184–90). The majority adequately reported the allowance or prohibition of concomitant topical treatments (96%, 64 of 67), but this clarity was less prevalent regarding rescue topicals (73%, 49 of 67). All trials permitting concomitant therapies consistently reported the type, although details on potency (89%, 31 of 35), duration (54%, 19 of 35), application frequency (34%, 12 of 35) and quantity (6%, 2 of 35) were less frequently reported. Similarly, trials allowing rescue treatments often specified the type (91%, 31 of 34) but provided limited information on potency (53%, 18 of 34), duration (9%, 3 of 34), application frequency (6%, 2 of 34) and quantity (0%, 0 of 34). Notably, only 24% (8 of 34) clearly reported the criteria for using rescue topical treatments, with the phrase ‘at investigator’s discretion’ being used in most cases (62%, 21 of 34). In multivariate logistic regression models, the variable ‘publication year ≥ 2020’ was significantly associated with reporting the use of rescue topicals (adjusted odds ratio 9.55, 95% confidence interval 1.73–83, P < 0.001). Indeed, 31 of 33 trials published in 2020 or after clearly reported their use. In conclusion, while most AD clinical trials of systemic treatments report concomitant topical treatments, reporting practices for rescue topicals were less consistent and inadequate. The observed association with clearer reporting in more recent publications suggests a positive trend. Nonetheless, a standardized approach to reporting topical therapy in AD trials is needed to enhance transparency and interpretability.
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Hegarty, Peter. "Donna J. Drucker. The Machines of Sex Research: Technology and the Politics of Identity, 1945–1985. (Springer Briefs in the History of Science and Technology.) x + 97 pp., illus., figs. Dordrecht: Springer, 2014. €52.99 (paper)." Isis 107, nr 2 (czerwiec 2016): 433–35. http://dx.doi.org/10.1086/687127.
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Yasyshena, Valentyna. "The evolution of intangible assets in terms of social and economic development concepts". Herald of Ternopil National Economic University, nr 4(90) (12.12.2018): 134–44. http://dx.doi.org/10.35774/visnyk2018.04.134.
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The article presents evidence that historically the emergence of intellectual property rights dates back to the pre-industrial stage of society’s development. The issuing of letters patent in England led to further development of intangible assets worldwide. The study considers chronologically social and economic development concepts which have been researched in academic papers of prominent scholars, namely, A. Smith, F. List, Knight, F. Machlup, W. Rostow, J. Galbraith, D. Bell, P. Drucker, and then highlights the key aspects that have affected the evolution of intangible assets. Thus, on the basis of reviewing the concepts developed by outstanding scholars, it is pointed out that the growth of intangible assets has been driven by knowledge and that a post-industrial society is based on unprecedented technological breakthroughs. Special reference is made to information viewed as the key production resource of a post-industrial society, whereas knowledge is seen as its internal source of progress. In a post-industrial society, people are regarded as capital. The essential importance and role of intellectual capital in company operations are embodied in professional and managerial skills of personnel. As shown in the article, there are not only research development concepts, but also normative documents, such as the Bulletin entitled «Amortization of intangible assets», in which intangible assets are identified as accounting items. Furthermore, the international system of intellectual property protection has been enhanced by the introduction of Paris and Berne Conventions. The paper also describes how the concept of intangible assets, which appeared in Ukraine’s legislation in 1993, is seen in the national legal system, specifically as intellectual property objects including industrial property and other items of property and use. With the introduction of Ukrainian Accounting Standards (UAS) 8 into the national legislation, it was firstly emphasized that intangible assets are non-monetary assets that, on the one hand, are non-material and, on the other hand, can be identified. The article also stresses that today’s society is passing a new stage of post-industrial development, which is accompanied not only by a rapid growth of service industries, science and education, but also by a significant increase of specialized knowledge in various fields. Finally, the need for further research of intangible assets is identified, since intangibles have a great impact on enterprise value and the competitiveness of the national economy as a whole.
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Bukotas, Gintaras, i Rimantas Kačianauskas. "ANALYSIS OF AXISYMMETRIC BORE-TYPE FOUNDATION IN RESPECT OF PLASTIC DEFORMATION/AŠIAI SIMETRINIO GRĘŽININIO PAMATO ANALIZĖ ĮVERTINANT PLASTINES DEFORMACIJAS". JOURNAL OF CIVIL ENGINEERING AND MANAGEMENT 3, nr 10 (30.06.1997): 24–31. http://dx.doi.org/10.3846/13921525.1997.10531680.
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In order to design efficient foundations, it is necessary to know exact behaviour of them and surrounding soil under the load. At present various numerical methods [1–11] are used to determine such response. The behaviour of axi-symmetric bored foundation is described in this paper. The finite element method is utilized in analysis of the foundation. Linear and non-linear properties of material are taken into account. The investigation of properties of soil, predominating in Lithuania, and economical constructing of foundation gives preference to bored foundation [12]. Schematically this type of foundation can be depicted as a cylindrical body resting on soil (Fig 1). Geometrically the foundation can be described through the diameter d and the height h. F denotes the vector of the axisymmetric load. Such bored foundation has ratio h/d ≥ 2 and transmit part of the external load through their side surface to soil. It is very difficult to achieve a shear failure of soil mass for such a type of foundation, but the foundation may suffer significant deflections. It is, therefore, important to known the stress-strain state of soil for design purpose. Various stress-strain models have been proposed for representing the behaviour of soil [14]. These range from very simple linear-elastic to complex elastic-plastic models. In general, the stress vector σ is related to the strain vector ε through the elasticity matrix [C] (1) [1,2]. The linear-elastic stress-strain model is the simplest. In this case matrix [C] is constant and history independent (2) [4]. More complex is the non-linear-elastic model. Two incremental linear-elastic approaches can be used to handle this problem [4]. In the first case a tangent and in the other—secant modulus are used. The described models imply that volume changes are induced by changes in mean normal effective stress alone, while shear strains are induced by shear stress alone. Investigation shows that volumetric strains are induced by changes in shear stress as well as by changes in the mean normal stress [4, 11]. This can be accounted for the dilatant-elastic stress-strain model. The incremental shear-induced volume change Δεv can be expressed in terms of a tangent dilation parameter αϵ [10] according to (4), in which Δγ is the increment of maximum shear strain [4]. The dilatant-elastic materials lead to a three parameter stress-strain model in which the increments of volumetric and shear strain are related to the corresponding stress increments according to (5). The most complex is the elastic-plastic stress-strain model. A basic assumption of elastic models is that the unloading path is identical to the loading path. This is generally not true for soils where the recoverable strain upon unloading is generally small. The recoverable strain is considered to be elastic, while the non-recoverable strain is considered to be plastic. There have been proposed various yield conditions to model those plastic properties of soils. Von Mises yield condition can be written (6) in terms of the second invariant of stress deviator J 2 and yield stress Y(κ) from uniaxial tests [2]. For soils, concrete and other ‘frictional’ materials the Drucker and Prager law (7) is frequently used [2,13]. In this law hydrostatic press σm is incorporated, while c and Φ are the cohesion and angle of friction, respectively [8]. The problem is formulated and analysed by the finite element method. The region of a model is subdivided into discrete elements. The global system of equations to be solved is described by the equation (9), where [K(U)] denotes the global non-linear stiffness matrix, U is the unknown deflection vector and F is the vector of nodal forces [1,2]. The matrix [K(U)] and the vector F can be made up by adding up the element stiffness matrices [k e(u e)] and the element nodal deflection vectors f e, respectively. Therefore the problem can be mathematically described through the governing equation of the separate element (10), where u e denotes the unknown element nodal deflection. The stiffness matrix can be determined from the principle of virtual work. This involves equating the work done by the internal stresses with that done by the nodal forces. In a non-linear analysis the matrix [k e(u e)] depends on the vector u e and solution of a problem must be obtained throughout the complete history of incremental load application [1]. Time is a convenient variable tthat denotes different intensities of load applications. Equality of virtual work is expressed through displacement increments Δu e in the time step Δt. In this case the relation of a governing equation is (11) where tpe , denotes nodal point forces corresponding to the element stresses at time t. A solution of (11) may be subject to very significant errors, it is, therefore, necessary to iterate until the solution is obtained to sufficient accuracy. The incremental equations, used in the Newton-Raphson iteration, are (12) and (13), for i= 1, 2, 3,…with the initial conditions shown in (14). The foundation and soil are considered a non-homogeneous deformable solid [2,4,9]. Two separate problems were formulated. The first problem deals with linear-elastic material properties. The other accounts for elastic-plastic properties of soil. Von Mises and Drucker-Prager yield conditions are applied. The formulation is geometrically linear and axisymmetric. The sketch of the model is depicted in Fig 2. The material properties of soil and concrete are chosen such, that predominate in Lithuania [15]. The ANSYS [5–8] computer code is used for the calculation. Another problem is to choose geometric dimensions of a soil model because it is possible to analyse the finite size model by finite element method. The width of a model D=3.75 d is chosen from the investigations of other authors [2, 9]. Some analyses were carried out in order to determine the influence of the soil depth under the foundation H = 2—4.333 h on the deflection at the top of the foundation. In this case the linear-elastic model was applied. The results are depicted in Fig 3. The depth H =2.167 h was chosen for further analysis. The generated discrete model was estimated for the quality. The model was under the circular in plane with the radius r = 0.4 m uniform distributed surface loading p = 1.989 MPa [16]. The calculated stress and strain distribution in soil under the centre of loading are compared, as shown in Fig 4 and 5, respectively. In case of non-linear analysis the load is applied in two stages. In the first stage the model is loaded by weight. The full external load p = 1.989 MPa is incrementally applied in the second stage. The history of load application is described through the time variable t. The history of the deflection at the top of the foundation is depicted in Fig 6. It seems that the deflection of linear model under the full 1 MN load and that of model, implemented with Drucker-Prager yield condition, differs by 11%. The distribution of accumulated equivalent plastic strain in the cross-section (Fig 7) of the model, utilizing the Drucker-Prager yield condition, shows that the biggest plastic deformation developed in the immediate contact with the foundation. The history of the principal stresses of the node under the foundation and Drucker-Prager and von Mises yield surfaces in principal stress space are depicted in Fig 8. Our analysis of axisymmetric bored foundation allows to know stress-strain state near the foundation. We can see that the external force of great magnitude cause significant plastic deformation, which, in turn, leads to significant deflection of the foundations.
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Kubba, Faris, Pakiza Aliyeva-Derraz i Alessandro Traniello Gradassi. "DP24 An unusual case of drug-induced annular granulomatous vasculitis in a patient with rheumatoid arthritis and type 2 diabetes mellitus". British Journal of Dermatology 191, Supplement_1 (28.06.2024): i117—i118. http://dx.doi.org/10.1093/bjd/ljae090.246.
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Abstract A 61-year-old Asian woman presented with acute onset of a widespread rash and 3–4-cm infiltrated erythematous plaques in the arms, legs and torso, with a few showing an annular configuration soon after he had taken naproxen for rheumatoid arthritis. After 48 h the plaques had developed into purpura and petechiae. Past medical history also included diabetes mellitus type 2, hypertension, left knee replacement, cauda equina syndrome and asthma. Her medications comprised losartan, atorvastatin, metformin, amlodipine and naproxen. The differential diagnosis included sarcoidosis, Wells syndrome, panniculitis and vasculitis. Histopathology of the 4-mm punch biopsy from the right flank showed mild spongiosis, focal lymphocyte exocytosis, focal basal vacuolar degeneration, superficial dermal oedema, mild superficial and deep dermal perivascular and perisudoral lymphocytic infiltrate with neutrophilic microabscesses, and leucocytoclasia associated with small histiocytic aggregates. Focal involvement of the subcutis was also present. No obvious collagen necrobiosis with histiocyte palisading, flame figures or increased eosinophils were seen. No medium vessel vasculitis was identified. Periodic acid–Schiff stain was negative for fungi, and Ziehl–Neelsen stain did not reveal acid-fast bacilli. Both vasculitis and viral screens were normal apart from elevated D-dimers, serum ferritin and positive Epstein–Barr virus DNA. Our working diagnosis was a neutrophilic and histiocytic dermatosis with leucocytoclastic vasculitis. Given the history of rheumatoid arthritis, a palisading neutrophilic granulomatous dermatitis was also considered, as the findings may vary according to the age of the lesion. However, the findings were best fitted to a vasculitic granulomatous drug reaction as there were focal vacuolar interface changes and obvious lymphocyte epidermotropism involving the entire epidermal thickness. There was no resemblance to other conditions like rheumatoid nodule, interstitial granuloma annulare or infective necrotizing granulomas. In their recent review, Shah et al. identified five patterns of drug-induced granulomatous dermatosis (Shah N, Shah M, Drucker AM et al. Granulomatous cutaneous drug eruptions: a systematic review. Am J Clin Dermatol 2021; 22: 39–53). They included (i) interstitial granulomatous drug reaction, (ii) drug-induced accelerated rheumatoid nodulosis, (iii) drug-induced granuloma annulare, (iv) drug-induced sarcoidosis and (v) miscellaneous presentations. The authors also concluded that polypharmacy and a prolonged lag period from drug intake to lesion onset would result in diagnostic challenges, as in our case. On suspension of naproxen, the rash had subsided and it resolved 2 weeks later. We have presented the case of a 60-year-old patient with an unusual granulomatous neutrophilic dermatitis associated with leucocytoclastic vasculitis that did not fit with the usual patterns described in association with rheumatoid arthritis. The final diagnosis was a vasculitic granulomatous drug reaction, secondary to naproxen, as suggested by the presence of epidermal changes and absence of significant systemic symptoms. Knowledge of this entity is helpful to distinguish these lesions from palisading neutrophilic granulomatous dermatitis and from other similar dermatosis. The lesions should resolve with discontinuation of the causative drug.
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Riazanova, Nataliia O. "FINANCIAL SUPPORT OF INDUSTRIAL ENTERPRISES ON THE BASIS OF PUBLIC-PRIVATE PARTNERSHIP". Vital cycle of the organizational culture of the trading enterprises 1, nr 14 (4.12.2021): 81–91. http://dx.doi.org/10.32342/2616-3853-2021-1-14-8.
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One of the main tasks of financial and economic policy of industrial enterprises is to create conditions for their sustainable development through the use of modern management tools that will promote the balance between resources and potential of enterprises. In particular, such a tool is management methods based on forms of interaction between the state and business in the framework of public-private partnership. The problem of managing sustainable development of industrial enterprises on the basis of public-private partnership, their financial support is covered in the works of such researchers and specialists as I. Ansoff, K. Bowman, P. Drucker, D. Cleland, G. Mintzberg, J. Strickland, A. Thompson, F. Berger, V. Varnavsky, M. Gerard, T. Crystal, A. Reid, T. Voronkova, E. Savas, L. Sharinger and other domestic and foreign authors. Recently, disparities in the gradual dynamics of the formation of financial resources within the state are obvious: revenue sources are centralized only at the state budget level, revenue liabilities are decentralized to the regional and local levels. The greatest impact on the financial autonomy of an industrial enterprise has the amount of own budget revenues, in particular its share in total consolidated revenues. Inter-budgetary transfers from the budget are one of the sources of income of industrial enterprises and to some extent determine the solvency of industrial enterprises. The main purpose of the system of intergovernmental relations, as well as the entire system of public finance, is to provide conditions for improving the quality of life. PPP is seen not only as a tool for financing and implementing individual projects, but as a form of interaction between the state and the private sector, which is built into the management system based on co-financing, risk and revenue sharing, pooling of professional knowledge that serves to achieve certain positive social , economic and political results and is a key element of the industrial enterprise’s strategy to ensure sustainable industrial and resource-sustainable development. The main purpose of public-private partnership in an industrial enterprise within the framework of sustainable development is to achieve public socio-economic interests through the implementation of infrastructure projects of an industrial enterprise. The basis of PPP’s institutional infrastructure in Ukraine can be industrial infrastructure, which operates not on the basis of state administrative structures, but independently. Problems such as improving the legal framework of the partnership, creating a single coordinating and regulatory body, expanding the base of PPP participants (more active involvement of small and medium-sized businesses), and developing a strategy for the development of this structure need to be addressed. The tools of inter-budgetary regulation are considered - inter-budgetary transfers that determine the solvency of an industrial enterprise. The internal risks of industrial enterprises are substantiated. The advantages and disadvantages of current methods of industrial management are noted. The forms of PPP used in Ukraine and abroad are described, the most effective of them are indicated. Deterrent factors of PPP development are determined. The model of PPP at the level of the industrial enterprise is offered. The principles of optimal functioning and development of PPP are determined.
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Stein, Andrew, Thea Kalebic i Dean Bottino. "Bcr-Abl Kinetics Suggest Self-Renewing Leukemic Cells Are Reduced During Imatinib Treatment." Blood 114, nr 22 (20.11.2009): 506. http://dx.doi.org/10.1182/blood.v114.22.506.506.
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Abstract Abstract 506 Background: In a majority of chronic myeloid leukemia patients treatment with imatinib (IM) induces durable hematologic, cytogenetic, and molecular responses, which in turn results in a dramatic improvement of progression-free survival. A new challenge for further optimizing the management of CML is to determine if treatment with TKIs such as IM could eventually cure the patients, particularly those with sustained undetectable disease, by reducing or eliminating the leukemic self-renewing cell (LSC) population thought to drive the disease. Given the challenges in directly assessing LSC burden in patients, we have applied mathematical modeling to molecular response data from patients on IM therapy to infer whether LSC levels can be reduced during IM treatment. Methods: To conduct our study we have utilized 281 patients on the IM arm of the International Randomized Study of Interferon Versus STI571 (IRIS) trial (Drucker et al., NEJM, 2006; 355, 2408). The 281 patients maintained a 90% dose intensity over the course of treatment (up to 7 years) and had a sufficient number of PCR samples above the quantitation limit to support parameter estimation. We have modeled the Bcr-Abl/Bcr transcript ratio time course R(t) as a biexponential (R(t) = Aeαt + Beβt ) and estimated the model parameters for each patient using maximum likelihood methods. The parameter α < 0 describes the rapid initial decline in log10(R) upon treatment start while β describes the shallower slope of the subsequent log10(R) kinetics (figure 1a). Results: nearly every patient response trajectory (93%-263/281) was well-described by the bi-exponential model. The key parameter β, corresponding to the steady-state per-year reduction in log10 transcript levels, ranged from a minimum = -9.2, lower quartile = -1.1, median = -0.6, upper quartile = -0.2, maximum = 10.5 (see figure 1b). Approximately 21% (54/263) of patients had β>0, suggestive of molecular relapse, while 79% (209/263) have β<0, corresponding to continued transcript decline. Discussion: The durable reduction in Bcr-Abl transcripts in the majority of patients has two possible interpretations: either LSCs are depleted at a rate β, or LSCs are not depleted but leukemic progenitor cells in the bone marrow have a median half-life of over one year in many patients. However, leukemic progenitor dynamics appear to occur at a time scale of months (Abe et al, Int J Hematol. 2008; 88, 471); thus a durable reduction in transcript level must correspond to a depletion of LSCs. Our hypothesis that IM induces LSC depletion is also consistent with the observation that 50% of patients maintain undetectable Bcr-Abl transcript levels upon treatment discontinuation (Guastafierro et al, Leukemia Res. 2009; 33, 1079). Conclusions: Mathematical modeling which combines pathophysiologic principles of CML with 7-year molecular response data in individual patients predicts that most patients (∼79%) experience reduction in LSC burden while on sustained IM treatment. In the future, this modeling approach can be used to analyze data from patients who stop IM after achieving CMR in the context of carefully conducted clinical trials, with the goal of assessing (a) the potential impact of IM interruption on LSC levels, particularly in those patients who relapse upon stopping IM and then are re-induced, and (b) whether the probability of achieving cure depends on duration of CMR, the steepness of response prior to achieving CMR (β), and/or additional factors. Disclosures: Stein: Novartis: Employment. Kalebic:Novartis: Employment. Bottino:Novartis: Employment.
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Androschuk, Gennady. "Global innovation index 2020: who will finance innovations". Law and innovations, nr 1 (33) (5.04.2021): 7–13. http://dx.doi.org/10.37772/2518-1718-2021-1(33)-1.
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Problem setting. The current state of the world economy is characterized by large-scale transformations, which are manifested in the development of key technologies of Industry 4.0, smart specialization, increasing international competition, accelerating all processes that become global and more open. For developing countries, including Ukraine, innovation is particularly important as it underpins industrialization, which plays a key role in diversifying the economy and overcoming its structural weakness. Industry is the engine of innovation, productivity growth and exports. Аnalysis of recent researches and publications. Numerous works by well-known foreign economists have devoted to the issues of innovative development of economic systems, research of innovations as a factor of sustainable growth and increase of competitiveness of the country in the conditions of globalization, digital transformation of economy: P. Drucker, M. Castells, F. Nixon, P. Fischer, J. Schumpeter, K. Schwab, L. Abalkin, A. Aganbegyan, A. Warsaw, L. Gokhberg, R. Greenberg, M. Delyagin, V. Inozemtsev, N. Ivanova, B. Kuzyk, D. Lviv. Also these issues were researched by Ukrainian specialists: G. Androschuk, L. Antonyuk, Y. Atamanova, Y. Bazhal, V. Bazylevych, O. Butnik - Siversky, V. Geets, V. Gusev, O. Zhilinska, I. Egorov, O. Kuzmin, L. Ligonenko B Malitsky, I. Makarenko, V. Muntiyan, V. Parkhomenko, S. Prilipko, V. Solovyov, V. Sidenko, O. Simson, N. Chukhrai, L. Fedulova, A. Yakovlev and others. At the same time, the multifaceted and complex nature of this issue, the dynamics of change in the world, especially during the pandemic COVID-19, require further research. The purpose of this research is to research the dynamics of innovation activity on an international scale based on the consolidated indicators of the Global Innovation Index for 2020, to determine the place of Ukraine in it. Article’s main body. Based on the consolidated indicators of the Global Innovation Index for 2020, the dynamics of innovation activity on an international scale is considered, a comparative analysis is conducted, the relative advantages and weaknesses of national innovation systems are identified, and Ukraine’s place is determined. In GII, Ukraine ranks 45th out of 131 countries, showing an overall increase in the ranking of the innovation index and in the sub-indices: + 20 positions in education and +10 in R&D. Ukraine also retained 2nd place among countries with below-average income. It is noted that the coronavirus pandemic has had a negative impact on innovation and caused a significant decline in national and global economies. At the same time, by affecting some industries, COVID-19 stimulates the development and funding of innovation in others, especially in the areas of computer technology, digitalization, and healthcare. The study confirmed the stability of innovative development of countries that have traditionally been leaders in this index in previous years. The crisis caused by COVID-19 can be a catalyst for innovation in many traditional industries, such as tourism, education and retail. It can also stimulate innovation in the organization of work processes at the level of enterprises and individual employees, as well as in the (re) organization of production locally and globally. Today, it is extremely important to unleash this potential, which requires government support, as well as models of interaction and further private sector investment in innovation. Conclusions and prospects for the development. In conclusion, it should be noted that GII continues to support and stimulate innovation in an era of change. The purpose of the next 13th analytical report is to provide meaningful data on innovations and thus help the representatives of policy-making bodies in assessing the effectiveness of innovation activities of their countries, making informed decisions on further state innovation policy. At this stage, with increasing one-sidedness and nationalism, it is important to remember that most countries that have improved their positions in GII over time have benefited significantly from integration into global value chains and innovation networks. China, Vietnam, India and the Philippines are good examples.
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Yevdokymov, V. A. "MANAGEMENT OF SUBORDINATES’ ACTIONS: HOW TO ENSURE THE ACCURACY OF OFFICIAL PUNISH?" 1, nr 1 (29.09.2022): 91–102. http://dx.doi.org/10.26565/1684-8489-2022-1-06.
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Аnnotation. Consistent and persistent efforts of Ukraine to become a member of the European Union require a systematic approach to further improvement of management activities in the field of public administration. Forced or accidental mistakes of public sphere managers occur as a result of low management qualifications, they do not provide an opportunity to bring the efficiency of public organizations to a fundamentally new level. Among the functions of management, motivation and punishment of subordinates are the most problematic, due to low attention to these aspects in domestic and foreign scientific literature. Recent research and publications analysis. Problems of improving managerial activity are studied in the works of such leading scientists and practitioners as I. Adizes, A. Fayol, H. Ford, V. Tarasov, O. Friedman, B. Tracy, P. Drucker, R. Blake, J. Mouton. However, many questions regarding the effective influence of a manager on subordinates remain open to this day. The paper objective is the analysis of complex negotiations with a subordinate during the punishment procedure, identification of subordinates’ typical techniques to avoid punishment, offering optimal options for the manager's response. The paper main body. The mechanism of conducting complex negotiations between a manager and a subordinate during the punishment procedure is analyzed. The typical methods of subordinates to avoid punishment are determined, and the optimal options for the manager’s response during this procedure are distinguished. It is emphasized that punishment is an integral part of the manager’s professional competence. It was found that moral punishment should be considered the most effective, because it acts as a prevention of administrative punishment application, while simultaneously forming a model of subordinate behavior in accordance with corporate norms. Moral punishment is carried out through the subordinate’s recognition of the fallacy of his actions through internal rethinking and correction of his/her ”picture of the world”. It is accentuated that manager should be punished for the violation, not its consequences. It is proved that management should include the approaches of theory X and theory Y according to the views of David McGregor. It is revealed that the punishment of a subordinate should not be accompanied by rudeness, disrespect, humiliation, insult, accusation, revenge, etc. The sequence of stages in complex negotiations with a subordinate is substantiated, the purpose and content of each stage is determined. Negotiations with subordinates during punishment should simultaneously solve several tasks: satisfy the interests of the case, improve relations with team, strengthen authority of the manager. A significant difference between the concepts of “mistake” and “misdemeanor” in the employee’s activity was determined. The manager’s readiness to punish subordinates can be considered as part of demandingness: the ability to demand from the subordinate a model of behavior that the manager considers correct in relation to existing corporate norms. Conclusions. The theoretical approaches discussed in the article require practical implementation and consolidation as skills. For this, it is recommended: First, it is advisable for the manager to take a critical look at the level of his management competencies development: planning, delegation and control. It are these functions that have the greatest impact on the accuracy of tasks performed by subordinates. Secondly, when implementing the method of punishment described above, it is necessary to prepare in advance for difficult negotiations with a subordinate. Perhaps this work will seem boring to a practicing manager, but the methodology should be written down in a synopsis and learned by heart. At first, it is better not to improvise, but to clearly act according to the algorithm. Thirdly, no matter how rude it may seem, but in order to consolidate the skill of punishing subordinates, the manager needs practice. It is necessary to start training on subordinates who do not feel sorry. This category includes those who constantly violate discipline and corporate regulations, employees with a low level of performance, insufficient responsibility, or those who should have been fired yesterday.