Artykuły w czasopismach: „DmCDPK”

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Thong, Nguyen Tho, Florentin Smarandache, Nguyen Dinh Hoa, Le Hoang Son, Luong Thi Hong Lan, Cu Nguyen Giap, Dao The Son i Hoang Viet Long. "A Novel Dynamic Multi-Criteria Decision Making Method Based on Generalized Dynamic Interval-Valued Neutrosophic Set". Symmetry 12, nr 4 (14.04.2020): 618. http://dx.doi.org/10.3390/sym12040618.

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Dynamic multi-criteria decision-making (DMCDM) models have many meaningful applications in real life in which solving indeterminacy of information in DMCDMs strengthens the potential application of DMCDM. This study introduces an extension of dynamic internal-valued neutrosophic sets namely generalized dynamic internal-valued neutrosophic sets. Based on this extension, we develop some operators and a TOPSIS method to deal with the change of both criteria, alternatives, and decision-makers by time. In addition, this study also applies the proposal model to a real application that facilitates ranking students according to attitude-skill-knowledge evaluation model. This application not only illustrates the correctness of the proposed model but also introduces its high potential appliance in the education domain.

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Nemets, E. A., A. E. Lazhko, A. M. Grigoriev, Yu B. Basok, A. D. Kirillova i V. I. Sevastianov. "Biocompatible and functional properties of a microdispersed tissue-specific 3D matrix from decellularized porcine cartilage". Russian Journal of Transplantology and Artificial Organs 24, nr 4 (29.07.2022): 73–84. http://dx.doi.org/10.15825/1995-1191-2022-4-73-84.

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In contrast to decellularization of soft tissues for use as tissue-specific matrices in the creation of tissue-engineered constructs, decellularization of cartilage tissue requires several processing techniques, which can negatively affect the biocompatibility and functional properties of the native extracellular matrix (ECM).Objective: to study the biocompatible and functional properties of microdispersed tissue-specific 3D matrix from a porcine cartilage that is decellularized by sequential use of chemical, physical and enzymatic techniques.Materials and methods. For decellularization, microdispersed cartilage particles (MCPs), obtained by cryomilling, were incubated in detergent solutions (sodium dodecyl sulfate and Triton X-100), then treated with supercritical carbon dioxide (scCO2) with 10% ethanol and DNase I. The Ames test (Salmonella typhimurium reverse mutation assay) was used to determine the genotoxicity of decellularized microdispersed cartilage particles (dMCPs). Local and general toxic effects, as well as resorption of dMCPs were studied in vivo on sexually mature outbred rats. Decellularized MCP specimens (10 mg) were implanted into the thigh muscle tissue. Viability of human adipose-derived mesenchymal stem/stromal cells (hAdMSCs), when cultured on dMCPs, was analyzed by in vivo microscopy, stained with fluorescent Calcein AM dye. Cell metabolic activity was assessed using PrestoBlue™ Cell Viability Reagent.Results. It has been proven that porcine dMCPs implanted in rat muscle after treatment with scCO2 do not exhibit local and general toxic effects, and do not show genotoxicity and negative effects on the reproductive system of animals. After 6 months of in vivo experiment, most (87%) of the implanted decellularized cartilage was resorbed. It was shown that the resulting matrices are able to support adhesion and proliferation of hAdMSCs. Conclusion. Porcine dMCP specimens are suitable for biocompatible medical products in terms of local and general toxic effects, genotoxicity and reproductive toxicity, and can be used as a matrix for creating cell- and tissue-engineered cartilage constructs.

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Zhang, Xubo, Yanan Ji, Bernard Moussian, Shumin Yang, Jianzhen Zhang, Tingting Zhang i Min Zhang. "Serpentine and Vermiform Are Produced Autonomously to Fulfill Their Function in Drosophila Wings". Insects 14, nr 5 (23.04.2023): 406. http://dx.doi.org/10.3390/insects14050406.

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Group I chitin deacetylases (CDAs), CDA1 and CDA2, play an essential role in cuticle formation and molting in the process of insect wing development. A recent report showed that trachea are able to take up a secreted CDA1 (serpentine, serp) produced in the fat body to support normal tracheal development in the fruit fly Drosophila melanogaster. However, whether CDAs in wing tissue were produced locally or derived from the fat body remains an open question. To address this question, we applied tissue-specific RNAi against DmCDA1 (serpentine, serp) and DmCDA2 (vermiform, verm) in the fat body or the wing and analyzed the resulting phenotypes. We found that repression of serp and verm in the fat body had no effect on wing morphogenesis. RT-qPCR showed that RNAi against serp or verm in the fat body autonomously reduced their expression levels of serp or verm in the fat body but had no non-autonomous effect on the expression in wings. Furthermore, we showed that inhibition of serp or verm in the developing wing caused wing morphology and permeability deficiency. Taken together, the production of Serp and Verm in the wing was autonomous and independent of the fat body.

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Kooliyat, Ragi, Joby Thomas Kakkassery, Vinod P. Raphael, Sini Varghese Cheruvathur i Binsi M. Paulson. "Synthesis, Cyclic Voltammetric, Electrochemical, and Gravimetric Corrosion Inhibition Investigations of Schiff Base Derived from 5,5-Dimethyl-1,3-cyclohexanedione and 2-Aminophenol on Mild Steel in 1 M HCl and 0.5 M H2SO4". International Journal of Electrochemistry 2019 (2.05.2019): 1–13. http://dx.doi.org/10.1155/2019/1094148.

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Schiff base 2,2’-(5,5-dimethylcyclohexane-1,3-diylidene)bis(azan-1-yl-1-ylidene) diphenol (DmChDp) was synthesized and characterized using spectroscopic methods (IR, UV, NMR, and Mass) and cyclic voltammetric (CV) studies. The corrosion inhibition potency of (DmChDp) on mild steel (MS) in 1M HCl and 0.5M H2SO4 was investigated. The corrosion monitoring techniques employed for this purpose are gravimetric and electrochemical methods (EIS and potentiodynamic polarization studies). The study reveals that the Schiff base, DmChDp, acts as excellent corrosion inhibitor on mild steel in 1M HCl. DmChDp obeys Langmuir adsorption isotherm both in 1M HCl and 0.5M H2SO4 on MS. Polarization studies show that DmChDp behaves as a mixed type inhibitor in both media. Scanning electron microscopic analysis established the protective nature of DmChDp on mild steel surface. The impact of temperature on the corrosion of MS was also evaluated using gravimetric method.

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Hayashi, S. "A Cdc2 dependent checkpoint maintains diploidy in Drosophila". Development 122, nr 4 (1.04.1996): 1051–58. http://dx.doi.org/10.1242/dev.122.4.1051.

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DNA replication in G2 does not normally occur due to the checkpoint control. To elucidate its mechanism, the functions of the escargot and Dmcdc2 genes of Drosophila were studied. When escargot function was eliminated, diploid imaginal cells that were arrested in G2 lost Cyclin A, a regulatory subunit of G2/M cdk, and entered an endocycle. escargot genetically interacted with Dmcdc2 which encodes a catalytic subunit of G2/M cdk. The mutant phenotypes of Dmcdc2 itself was similar to those of escargot: many diploid cells in imaginal discs, salivary glands and the central nervous system entered an endocycle and sometimes formed polytene chromosomes. Since mitotically quiescent abdominal histoblasts still required Dmcdc2 to remain diploid, the inhibitory activity of G2/M cdk on DNA replication appeared to be separable from its activity as the mitosis promoting factor. These results suggest that in G2, escargot is required to maintain a high level of G2/M cdk that actively inhibits the entry into S phase.

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Dresser, Michael E., Debra J. Ewing, Michael N. Conrad, Ana M. Dominguez, Robert Barstead, Hua Jiang i Thomas Kodadek. "DMC1 Functions in a Saccharomyces cerevisiae Meiotic Pathway That Is Largely Independent of the RAD51 Pathway". Genetics 147, nr 2 (1.10.1997): 533–44. http://dx.doi.org/10.1093/genetics/147.2.533.

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Meiotic recombinationin the yeast Saccharomyces cerevisiae requires two similar recA-like proteins, Dmc1p and Rad51p. A screen for dominant meiotic mutants provided DMC1-G126D, a dominant allele mutated in the conserved ATP-binding site (specifically, the A-loop motif) that confers a null phenotype. A recessive null allele, dmc1-K69E, was isolated as an intragenic suppressor of DMC1-G126D. Dmc1-K69Ep, unlike Dmc1p, does not interact homotypically in a two-hybrid assay, although it does interact with other fusion proteins identified by two-hybrid screen with Dmc1p. Dmc1p, unlike Rad51p, does not interact in the two-hybrid assay with Rad52p or Rad54p. However, Dmc1p does interact with Tid1p, a Rad54p homologue, with Tid4p, a Rad16p homologue, and with other fusion proteins that do not interact with Rad51p, suggesting that Dmc1p and Rad51p function in separate, though possibly overlapping, recombinational repair complexes. Epistasis analysis suggests that DMC1 and RAD51 function in separate pathways responsible for meiotic recombination. Taken together, our results are consistent with a requirement for DMC1 for meiosis-specific entry of DNA double-strand break ends into chromatin. Interestingly, the pattern on CHEF gels of chromosome fragments that result from meiotic DNA double-strand break formation is different in DMC1 mutant strains from that seen in rad50S strains.

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Reddy, J. N., Matthew Martinez i Praneeth Nampally. "A novel numerical method for the solution of nonlinear equations with applications to heat transfer". International Journal of Numerical Methods for Heat & Fluid Flow 31, nr 6 (11.02.2021): 1884–904. http://dx.doi.org/10.1108/hff-07-2020-0397.

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Purpose The purpose of this study is to extend a novel numerical method proposed by the first author, known as the dual mesh control domain method (DMCDM), for the solution of linear differential equations to the solution of nonlinear heat transfer and like problems in one and two dimensions. Design/methodology/approach In the DMCDM, a mesh of finite elements is used for the approximation of the variables and another mesh of control domains for the satisfaction of the governing equation. Both meshes fully cover the domain but the nodes of the finite element mesh are inside the mesh of control domains. The salient feature of the DMCDM is that the concept of duality (i.e. cause and effect) is used to impose boundary conditions. The method possesses some desirable attributes of the finite element method (FEM) and the finite volume method (FVM). Findings Numerical results show that he DMCDM is more accurate than the FVM for the same meshes used. Also, the DMCDM does not require the use of any ad hoc approaches that are routinely used in the FVM. Originality/value To the best of the authors’ knowledge, the idea presented in this work is original and novel that exploits the best features of the best competing methods (FEM and FVM). The concept of duality is used to apply gradient and mixed boundary conditions that FVM and its variant do not.

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Ozkan, Burak, Cagri A. Uysal, Ayse Ebru Abali i Mehmet Haberal. "600 Reconstruction of Finger Contracture with an Expanded Dorsal Metacarpal Artery Perforator Flap". Journal of Burn Care & Research 43, Supplement_1 (23.03.2022): S139. http://dx.doi.org/10.1093/jbcr/irac012.228.

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Abstract Introduction The first dorsal metacarpal artery perforator (DMCAP) flap is frequently used to cover exposed bone, tendon and neurovascular structures in the hand after trauma and burns. The size and width of DMCAP flap is limited and rotation arc generally lets to cover defects up to middle phalanx. Expansion of the DMCAP flap has not been reported in the literature and this technique might be solution to increase flap viability and size in order to cover defects up to distal phalanx. In this study, we will describe utilization of tissue expander to first DMCAP and present a case of electric burns in with flexor contracture. Methods A nine-year-old male patient applied to our clinic with the complaint of inability to extend the second finger of the left hand after an electrical burn. Physical examination revealed flexor contracture in the distal interphalangeal (DIP) and proximal interphalangeal (PIP) joints. Reconstruction was planned for the patient with a two-session expanded first DMCAP flap. In the first session, a 16 cc 5x3 cm tissue expander placed through a 3 cm vertical incision at the fifth metacarpal level. From the second postoperative week, the tissue expander was inflated with 1 ml of isotonic three days a week. Six weeks later, the DMCAP area was enlarged by giving 45 cc saline. Results In the second session, contractures at the level of the left hand 2nd finger DIP and PIP were excised.. Left hand 2nd finger was fixated in extension with K-wire. 9x3 cm DMCAP flap was elevated by dissection over the paratenon and the pedicle was preserved. The flap was adapted to the defect area on the volar face with 180-degree rotation angle. The flap donor site was closed primarily. There were no complications in the post-operative period. K-wire was removed at 6 weeks postoperatively. The patient was referred to the physical therapy. Conclusions In cases where the tissue defect cannot be closed with loco regional flaps, extra tissue can be provided by free flaps or using tissue expanders. Primary closure of the donor area, appropriate flap thickness for the finger, and aesthetically pleasing results are among the advantages of the expanded DMCA flap.. However, in tissue expander applications in the upper extremity, the patient should be followed closely, and pain and finger circulation should be constantly questioned.

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Han, Guang Wei, Cheng Ning Zhang, Shuo Zhang i Xiao Hua Wu. "Control Strategy of the Dual Motors Coupling Propulsion for Battery Electric Buses". Applied Mechanics and Materials 528 (luty 2014): 364–70. http://dx.doi.org/10.4028/www.scientific.net/amm.528.364.

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A novel drive system the Dual Motors Coupling Propulsion (DMCP) for battery electric buses was proposed, and its structure and working principle were introduced. For the power and comfort performance of the vehicle, the control method of the motors and the coordinated control strategy of the DMCP were developed. The co-simulation platform of AMESim and Simulink was established, based on which the dynamic model of the vehicle equipped the DMCP was built. The simulation results show that the DMCP runs smoothly in the Chinese typical city bus driving schedule. This indicates that the control strategy can manipulate the DMCP to drive the bus powerfully and smoothly. This has laid the foundation of the further research of the DMCP.

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Monzón, César Octavio. "Editorial". Revista Mexicana de Ciencias Forestales 6, nr 28 (13.03.2018): 6–7. http://dx.doi.org/10.29298/rmcf.v6i28.232.

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El departamento de Madera, Celulosa y Papel (DMCyP), Ing. Karl Augustin Grellmann, fue creado en 1970, en un inicio como un instituto que dependía de la Escuela de Graduados de la Universidad de Guadalajara; en 1977 se reubicó a las instalaciones que hoy ocupa. Actualmente, pertenece a la División de Ingenierías del Centro Universitario de Ciencias Exactas e Ingenierías (CUCEI) de dicha universidad. La misión del DMCyP incluye la formación de recursos humanos que respondan a los retos nacionales del presente; proveer de conocimiento de vanguardia a los profesionales del sector; así como, la búsqueda de soluciones a problemas, mediante la innovación e investigación; además de, generar y transferir conocimiento a los sectores académicos, industriales y sociales que promueva el uso responsable de los recursos forestales. El DMCyP es una institución académica dedicada a la investigación científica y el desarrollo tecnológico que busca contribuir a la innovación del uso sustentable de los recursos renovables, principalmente forestales, para incrementar la competitividad del país.

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Yezzi, M. J., I. E. Hsieh i G. H. Caughey. "Mast cell and neutrophil expression of dog mast cell protease-3. A novel tryptase-related serine protease." Journal of Immunology 152, nr 6 (15.03.1994): 3064–72. http://dx.doi.org/10.4049/jimmunol.152.6.3064.

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Abstract In previous work the primary structure of a previously unknown protease was deduced from the sequence of a dog mastocytoma cDNA. The predicted preproprotein shares some features with mast cell tryptases but is no more than 49% identical in sequence to known trypsin-like enzymes, including dog tryptase. This study explores the expression of this protein, termed dog mast cell protease-3 (dMCP-3). A polyclonal Ab was raised to a peptide corresponding to residues 166-181 of the deduced sequence. Anti-dMCP-3(166-181) Ig recognizes dMCP-3 expressed as a CheY fusion protein in Escherichia coli and binds to a approximately 36-kDa protein in extracts of dog mastocytomas. The Ab does not recognize dog tryptase, dMCP-3s closest known relative in mastocytoma cells. When used with fluorescein-conjugated and alkaline phosphatase-conjugated secondary Abs, anti-dMCP-3(166-181) Ig yields punctate cytoplasmic staining in mastocytoma cells, suggesting localization to intracellular granules. Staining is greatly reduced by preincubation with synthetic dMCP-3 peptide, supporting the specificity of the Ab. Immunohistochemical staining of normal dog tissues reveals scattered dMCP-3 reactive cells in skin, intestine, trachea, and lung parenchyma. Double staining with Ab and methylene blue shows that anti-dMCP-3(166-188) Ig recognizes extravascular mononuclear tissue cells with metachromatic granules. In addition, cytoplasmic staining is seen in polymorphonuclear leukocytes within vessels in tissue sections and in leukocytes harvested from blood. Hybridization of dMCP-3 cDNA to dog skin RNA provides further evidence of dMCP-3 gene transcription in normal tissue. Thus, this study provides immunochemical evidence of dMCP-3 expression in dog mast cell tumors, normal tissue mast cells, and neutrophils.

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Angaroni, Mariangela, G. Attilio Ardizzoia, Girolamo La Monica, Egle Maria Beccalli, Norberto Masciocchi i Massimo Moret. "Co-ordinative versatility of the dmcpz ligand (Hdmcpz = 3,5-dimethoxycarbonylpyrazole) in copper compounds. Synthesis, characterization and crystal structures of [Cu(dmcpz)2(py)2] and [Cu3(dmcpz)6](py = pyridine)". Journal of the Chemical Society, Dalton Transactions, nr 18 (1992): 2715. http://dx.doi.org/10.1039/dt9920002715.

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Liu, Chun-An, Yuping Wang i Aihong Ren. "New Dynamic Multi-Objective Constrained Optimization Evolutionary Algorithm". Asia-Pacific Journal of Operational Research 32, nr 05 (październik 2015): 1550036. http://dx.doi.org/10.1142/s0217595915500360.

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For dynamic multi-objective constrained optimization problem (DMCOP), it is important to find a sufficient number of uniformly distributed and representative dynamic Pareto optimal solutions. In this paper, the time period of the DMCOP is first divided into several random subperiods. In each random subperiod, the DMCOP is approximately regarded as a static optimization problem by taking the time subperiod fixed. Then, in order to decrease the amount of computation and improve the effectiveness of the algorithm, the dynamic multi-objective constrained optimization problem is further transformed into a dynamic bi-objective constrained optimization problem based on the dynamic mean rank variance and dynamic mean density variance of the evolution population. The evolution operators and a self-check operator which can automatically checkout the change of time parameter are introduced to solve the optimization problem efficiently. And finally, a dynamic multi-objective constrained optimization evolutionary algorithm is proposed. Also, the convergence analysis for the proposed algorithm is given. The computer simulations are made on four dynamic multi-objective optimization test functions and the results demonstrate that the proposed algorithm can effectively track and find the varying Pareto optimal solutions or the varying Pareto fronts with the change of time.

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Arjomandi, Jalal, i Rudolf Holze. "Electrochemical preparation and in situ characterization of poly(3-methylpyrrole) and poly(3-methylpyrrole-cyclodextrin) films on gold electrodes". Open Chemistry 6, nr 2 (1.06.2008): 199–207. http://dx.doi.org/10.2478/s11532-008-0020-9.

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AbstractA Electrosynthesis of conducting poly(3-methylpyrrole) (P3MPy) and poly(3-methylpyrrole-2,6-dimethyl-β-cyclodextrin) (poly(3MPy-β-DMCD)) films on a gold electrode in acetonitrile electrolyte solution containing lithium perchlorate has been carried out by potential cycling. Products were characterized with cyclic voltammetry CV, in situ UV-Vis spectroscopy, and in situ resistance measurements. Electrosynthesis of poly(3MPy-β-DMCD) started with a (1:1) (3MPy-β-DMCD) supramolecular cyclodextrin CD complex of 3-methylpyrrole characterized with proton NMR spectroscopy. The oxidation peak of poly(3MPy-β-DMCD) in CVs is shifted to more positive values than P3MPy. In situ resistance measurements show that the resistance of poly(3MPy-β-DMCD) is higher than of P3MPy by approximately an order of magnitude. Minimum resistance can be observed for P3MPy and poly(3MPy-β-DMCD) at 0.40 E Ag/AgClE Ag/AgClIn situ UV-Vis spectroelectrochemical data for both films prepared potentiodynamically by cycling the potential in the range −0.20 E Ag/AgCl

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Li, Hong Xin, Jin Hai Su, Chuan Fu Zhang i Chun Yu Shao. "A Key Management Scheme Based on Double Matrix CPK for Mobile Ad Hoc Networks". Applied Mechanics and Materials 40-41 (listopad 2010): 543–48. http://dx.doi.org/10.4028/www.scientific.net/amm.40-41.543.

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A robust and efficient key management scheme is necessary for mobile ad hoc networks (MANETs) to ensure its security. CPK (Combined Public Key) is a recently developed public key algorithm, which has advantages comparing with other public key system, such as low storage overhead and calculation demand. Some key management approaches based on CPK have been proposed for MANETs in recent years. However, CPK is vulnerable to collusion attack which may bring about terrible threats. In this paper, a novel key management scheme based on double matrix CPK (DMCPK) is put forward, which is resistant to collusion attack. This key management scheme is described in details, including key generation and updating. Simulation experiments are implemented based on the simulation tool OPNET and show the effectiveness of the proposed scheme.

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ZULUETA, YELENY, JUAN MARTÍNEZ-MORENO, RAFAEL BELLO PÉREZ i LUIS MARTÍNEZ. "A DISCRETE TIME VARIABLE INDEX FOR SUPPORTING DYNAMIC MULTI-CRITERIA DECISION MAKING". International Journal of Uncertainty, Fuzziness and Knowledge-Based Systems 22, nr 01 (luty 2014): 1–22. http://dx.doi.org/10.1142/s0218488514500019.

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While Multi-Criteria Decision Making (MCDM) models are focused on selecting the best alternative from a finite number of feasible solutions according to a set of criteria, in Dynamic Multi-Criteria Decision Making (DMCDM) the selection process also takes into account the temporal performance of such alternatives during different time periods. In this paper a new discrete time variable index is proposed, to handling differences in temporal behavior of alternatives, which are not discriminated in preceding dynamic approaches, also considering rating-based perspectives for discrimination of the decision maker by modeling different attitudes to deal with the rating changes along different time periods. Moreover a DMCDM for supplier selection example is provided to illustrate the feasibility and effectiveness of the proposed index.

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Varakin, V. N., i A. P. Simonov. "UV Laser Induced Chemistry of Adsorbed Dimethylcadmium". Laser Chemistry 12, nr 3-4 (1.01.1992): 181–97. http://dx.doi.org/10.1155/lc.12.181.

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The UV laser chemistry of dimethylcadmium (DMCd) either chemisorbed at 297 K on n-type Si(100) with native oxide or physisorbed at 150 K on a photodeposited cadmium film has been studied by using mass spectrometry of desorbed species. A XeCl laser induced the heterogeneous fragmentation of these chemisorbed molecules as well as the desorption of DMCd, Cd, and CH3. The resonant absorption of a KrCl laser radiation by adsorbed DMCd led to their photolysis and the ejection of DMCd and its fragments in both neutral and ionic forms. The kinetic, laser fluence, and time-of-flight dependences of desorbed species have been measured to elucidate the mechanisms of the dissociative and desorption processes either induced by lasers or occurring spontaneously. The effects of these lasers on chemisorbed DMCd as well as KrCl laser assisted processes in chemisorbed and physisorbed molecules have been compared.

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Tryndyak, Volodymyr P., Rose A. Willett, Todd Bourcier, Frederick A. Beland i Igor P. Pogribny. "Abstract 6017: Exposure-related DNA methylation and gene expression changes in mammary glands of Sprague Dawley rats treated with lorcaserin". Cancer Research 83, nr 7_Supplement (4.04.2023): 6017. http://dx.doi.org/10.1158/1538-7445.am2023-6017.

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Abstract The development of cancer in humans is caused by irreversible modifications of the genome through genetic or epigenetic alterations resulting in the acquisition of multiple heritable abnormal cellular phenotypes. We have investigated DNA methylation and gene expression alterations in mammary glands of Sprague Dawley rats induced by treatment with the weight-loss drug lorcaserin, a drug that increased the cancer incidence in a human clinical trial (CAMELLIA-TIMI 61) and in rats. Female Sprague Dawley rats received lorcaserin by gavage 7 days/week for 12 weeks, at doses previously used in a 2-year rodent cancer bioassay (0, 30, and 100 mg/kg bw/day). DNA methylation changes were investigated in mammary glands, a target organ for lorcaserin carcinogenicity in rats, by reduced representation bisulfite sequencing. Gene expression changes were analyzed by RNA sequencing. Lorcaserin exposure resulted in dose-dependent DNA methylation alterations in the mammary glands, as evidenced by the presence of 1832 and 2352 significantly differentially methylated CpG (dmCpG) sites in the 30 and 100 mg/kg bw/day treatment groups, respectively, as compared to the control group, among which 593 sites were hypomethylated or hypermethylated in common. Similar to DNA methylation changes, lorcaserin treatment resulted in dose-dependent changes in gene expression. Pathway enrichment analysis of the dmCpG-containing genes demonstrated a strong representation of genes associated with cell morphology, cellular function and maintenance, and cellular growth and proliferation. Analysis of dmCpG sites indicated an increase in the number of hypermethylated sites compared to the number of hypomethylated sites in both 30 (1.9 fold) and 100 (2.6 fold) mg/kg bw/day treatment groups. Furthermore, while the number of hypomethylated CpG sites did not differ between treatment groups, the number of hypermethylated CpG sites in rats treated with 100 mg/kg bw/day of lorcaserin was 1.4 times greater than in rats treated with 30 mg/kg bw/day. By combining the analysis of differentially expressed genes and dmCpG sites, we identified 13 genes (11 hypermethylated and 2 hypomethylated) the expression of which was inversely correlated with DNA methylation in the mammary glands of rats treated with 100 mg/kg bw/day of lorcaserin. We also identified 41 hypermethylated and 17 hypomethylated genes containing more than two dmCpG sites. In summary, we have demonstrated that lorcaserin induces extensive DNA methylation and transcriptomic changes in mammary glands at early preneoplastic stages of lorcaserin-induced rat carcinogenesis. These findings suggest the importance of these non-genotoxic alterations in the carcinogenicity of lorcaserin. Citation Format: Volodymyr P. Tryndyak, Rose A. Willett, Todd Bourcier, Frederick A. Beland, Igor P. Pogribny. Exposure-related DNA methylation and gene expression changes in mammary glands of Sprague Dawley rats treated with lorcaserin [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 6017.

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Wang, Wenwei, Hong Pan i Lin Cheng. "Energy management of a dual-motor driven city bus based on reformed dynamic programming". E3S Web of Conferences 236 (2021): 02020. http://dx.doi.org/10.1051/e3sconf/202123602020.

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This paper proposes a reformed dynamic programming (DP) based energy management strategy for a city bus driven by dual-motor coupling propulsion system(DMCPS). An instantaneous optimal problem of DMCPS’s total energy loss is constructed to solve the torque allocation between two motors. Taking the results as extra constraints, a reformed DP architecture aimed at optimal energy consumption is established, where the state variables are the battery’s SOC and operating modes of DMCPS, with a sole decision variable of mode switching action. The optimization results show a close performance to the original method, with the calculation efficiency greatly improved and the calculation time reduced by nearly 97%. To obtain practical rules for real-time application, the mode switching schedule is extracted based on a RBF-SVM classifier, and the torque allocation is ruled by linear function. Simulation results demonstrate that the extracted rules can be executed through an on-board processor, with energy consumption reduced by 2.19% compared to the original rule-based strategy.

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Lopes, M. I. F., L. E. Miyazaki, R. D. R. Oliveira, F. F. L. Souza, S. C. L. Almeida i P. J. Louzada. "RESPOSTA ÀS DMCDS SINTÉTICAS NO TRATAMENTO DA ARTRITE REUMATOIDE INICIAL". Revista Brasileira de Reumatologia 57 (2017): S38. http://dx.doi.org/10.1016/j.rbr.2017.06.067.

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SCHNITZLER, Egon, Wilson COSTA, Cristo Bladimiros MELIOS, Maria Ines Gonçalves LELES i Massao IONASHIRO. "Thermal behavior studies of solid state compounds of 4-dimethylaminocinnamylidenepyruvate with alkali earth metals, except beryllium and radium". Eclética Química 25 (2000): 31–39. http://dx.doi.org/10.1590/s0100-46702000000100003.

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Solid state compounds of general formula M(DMCP)2.nH2O, where M represents Mg, Ca, Sr, Ba, and DMCP is 4-dimethylaminocinnamylidenepyruvate, and n = 1, except for Ca, where n = 2.5, have been prepared. Thermogravimetry, derivative thermogravimetry (TG, DTG), differential scanning calorimetry (DSC), X-ray diffraction powder patterns and complexometry were used to characterize and to study the thermal decomposition of these compounds.

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Schnitzler, Egon, Cristo Bladimiros Melios, Maria Inês Gonçalves Leles i Massao Ionashiro. "Thermal behavior studies of solid state compounds of 4-dimethylaminocinnamylidenepyruvate with alkali earth metals, except beryllium and radium". Ecletica Quimica 25, nr 1 (4.12.2000): 31–39. http://dx.doi.org/10.26850/1678-4618eqj.v25.1.2000.p31-39.

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Solid state compounds of general formula M(DMCP)2.nH2O, where M represents Mg, Ca, Sr, Ba, and DMCP is 4-dimethylaminocinnamylidenepyruvate, and n = 1, except for Ca, where n = 2.5, have been prepared. Thermogravimetry, derivative thermogravimetry (TG, DTG), differential scanning calorimetry (DSC), X-ray diffraction powder patterns and complexometry were used to characterize and to study the thermal decomposition of these compounds.

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LELES, Maria Ines Gonçalves, Cristo Bladimiros MELIOS, Lázaro Moscardini D’ASSUNÇÃO i Massao IONASHIRO. "Preparation and thermal behavior of mixture of basic carbonate and 4-dimethylaminocinnamylidenepyruvate with lanthanides (III) and yttrium (III) in the solid state". Eclética Química 24 (1999): 29–44. http://dx.doi.org/10.1590/s0100-46701999000100003.

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Solid Ln-OHCO3-DMCP compounds, where Ln represents lanthanides (III) and yttrium (III) ions and DMCP is the anion 4-dimethylaminocinnamylidenepyruvate, have been prepared. Thermogravimetry, derivative thermogravimetry (TG, DTG), differential scanning calorimetry (DSC), x-Ray diffraction powder patterns and elemental analysis have been used to characterize the compounds. The thermal stability as well as the thermal decomposition of these compounds were studied using an alumina crucible in an air atmosphere.

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Leles, Maria Inês Gonçalves, Cristo Bladimiros Melios, Lázaro Moscardini D'Assunção i Massao Ionashiro. "Preparation and thermal behavior of mixture of basic carbonate and 4-dimethylaminocinnamylidenepyruvate with lanthanides (III) and yttrium (III) in the solid state". Ecletica Quimica 24, nr 1 (6.12.1999): 29–44. http://dx.doi.org/10.26850/1678-4618eqj.v24.1.1999.p29-44.

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Solid Ln-OHCO3-DMCP compounds, where Ln represents lanthanides (III) and yttrium (III) ions and DMCP is the anion 4-dimethylaminocinnamylidenepyruvate, have been prepared. Thermogravimetry, derivative thermogravimetry (TG, DTG), differential scanning calorimetry (DSC), x-ray diffraction powder patterns and elemental analysis have been used to characterize the compounds. The thermal stability as well as the thermal decomposition of these compounds were studied using an alumina crucible in an air atmosphere.

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25

Schnitzler, Egon, Márcio Lazzarotto, Marco Aurelio da Silva Carvalho-Filho i Massao Ionashiro. "Thermoanalytical study of the complexes of 4-dimethylaminocynnamylidenepyruvate with manganese (II), cobalt (II), nickel (II), copper (II), zinc (II) and lead (II), in the solid state". Ecletica Quimica 27, nr 1 (2.12.2002): 41–50. http://dx.doi.org/10.26850/1678-4618eqj.v27.1.2002.p41-50.

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Solid state compounds M-4-DMCP, where 4-DMCP is 4-dimethylaminocinnamylidenepyruvate and M represents Mn (II), Co (II), Ni (II), Cu (II), Zn (II) and Pb (II) were prepared. These compounds were studied by thermoanalitycal techniques: thermogravimetry (TG), derivative thermogravimetry (DTG), differential scanning calorimetry (DSC), X-ray diffraction powder patterns and complexometric titration with EDTA. From the results obtained by the complexometric titration with EDTA, TG, DTG and DSC curves, was possible to establish the hydration degree, stoichiometry and thermal stability of the prepared compounds.

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Affinito, Ornella, Paolo Salerno, Alfonso D’Alessio, Mariella Cuomo, Ermanno Florio, Francesca Carlomagno, Agnese Proietti i in. "Association between DNA methylation profile and malignancy in follicular-patterned thyroid neoplasms". Endocrine-Related Cancer 26, nr 4 (kwiecień 2019): 451–62. http://dx.doi.org/10.1530/erc-18-0308.

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Molecular differentiation between benign (follicular thyroid adenoma (FTA)) and malignant (follicular thyroid carcinoma (FTC)) thyroid neoplasms is challenging. Here, we explored the genome-wide DNA methylation profile of FTA (n.10) and FTC (n.11) compared to normal thyroid (NT) (n.7) tissues. FTC featured 3564 differentially methylated CpGs (DMCpG), most (84%) of them hypermethylated, with respect to normal controls. At the principal component analysis (PCA), the methylation profile of FTA occupied an intermediate position between FTC and normal tissue. A large fraction (n. 2385) of FTC-associated DMCpG was related (intragenic or within 1500 bp from the transcription start site) to annotated genes (n. 1786). FTC-hypermethylated genes were enriched for targets of the Polycomb transcriptional repressor complex and the specific histone H3 marks (H3K4me2/me3-H3K27me3) found in chromatin domains known as ‘bivalent’. Transcriptome profiling by RNAseq showed that 7.9% of the DMCpGs-associated genes were differentially expressed in FTC compared to NT, suggesting that altered DNA methylation may contribute to their altered expression. Overall, this study suggests that perturbed DNA methylation, in particular hypermethylation, is a component of the molecular mechanisms leading to the formation of FTC and that DNA methylation profiling may help differentiating FTCs from their benign counterpart.

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Miyazaki, L. E., M. I. F. Lopes, R. D. R. Oliveira, S. C. L. Almeida, P. J. Louzada i F. F. L. Souza. "OCORRÊNCIA DE HEPATOTOXICIDADE NO TRATAMENTO DA ARTRITE REUMATOIDE INICIAL COM DMCDS SINTÉTICAS". Revista Brasileira de Reumatologia 57 (2017): S27—S28. http://dx.doi.org/10.1016/j.rbr.2017.06.049.

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Anonymous, Anonymous. "Abdominal Aortic Tourniquet™ Use in Afghanistan". Journal of Special Operations Medicine 13, nr 2 (2013): 1. http://dx.doi.org/10.55460/hljc-dmck.

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Zhang, Haiyan, Chao Ye i Zhaoyuan Ning. "Dependence of Decamethylcyclopentasiloxane (DMCPS) Dissociation on Ionized Energy by Using Quadrupole Mass Spectrum". Plasma Science and Technology 12, nr 6 (grudzień 2010): 677–80. http://dx.doi.org/10.1088/1009-0630/12/6/08.

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Soundararajan, Rajasoundaran, Prince Mary Stanislaus, Senthil Ganesh Ramasamy, Dharmesh Dhabliya, Vivek Deshpande, Sountharrajan Sehar i Durga Prasad Bavirisetti. "Multi-Channel Assessment Policies for Energy-Efficient Data Transmission in Wireless Underground Sensor Networks". Energies 16, nr 5 (27.02.2023): 2285. http://dx.doi.org/10.3390/en16052285.

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Wireless Underground Sensor Networks (WUGSNs) transmit data collected from underground objects such as water substances, oil substances, soil contents, and others. In addition, the underground sensor nodes transmit the data to the surface nodes regarding underground irregularities, earthquake, landslides, military border surveillance, and other issues. The channel difficulties of WUGSNs create uncertain communication barriers. Recent research works have proposed different types of channel assessment techniques and security approaches. Moreover, the existing techniques are inadequate to learn the real-time channel attributes in order to build reactive data transmission models. The proposed system implements Deep Learning-based Multi-Channel Learning and Protection Model (DMCAP) using the optimal set of channel attribute classification techniques. The proposed model uses Multi-Channel Ensemble Model, Ensemble Multi-Layer Perceptron (EMLP) Classifiers, Nonlinear Channel Regression models and Nonlinear Entropy Analysis Model, and Ensemble Nonlinear Support Vector Machine (ENLSVM) for evaluating the channel conditions. Additionally, Variable Generative Adversarial Network (VGAN) engine makes the intrusion detection routines under distributed environment. According to the proposed principles, WUGSN channels are classified based on the characteristics such as underground acoustic channels, underground to surface channels and surface to ground station channels. On the classified channel behaviors, EMLP and ENLSVM are operated to extract the Signal to Noise Interference Ratio (SNIR) and channel entropy distortions of multiple channels. Furthermore, the nonlinear regression model was trained for understanding and predicting the link (channel behaviors). The proposed DMCAP has extreme difficulty finding the differences of impacts due to channel issues and malicious attacks. In this regard, the VGAN-Intrusion Detection System (VGAN-IDS) model was configured in the sensor nodes to monitor the channel instabilities against malicious nodes. Thus, the proposed system deeply analyzes multi-channel attribute qualities to improve throughput in uncertain WUGSN. The testbed was created for classified channel parameters (acoustic and air) with uncertain network parameters; the uncertainties of testbed are considered as link failures, noise distortions, interference, node failures, and number of retransmissions. Consequently, the experimental results show that DMCAP attains 10% to 15% of better performance than existing systems through better throughput, minimum retransmission rate, minimum delay, and minimum energy consumption rate. The existing techniques such as Support Vector Machine (SVM) and Random Forest (RF)-based Classification (SMC), Optimal Energy-Efficient Transmission (OETN), and channel-aware multi-path routing principles using Reinforcement Learning model (CRLR) are identified as suitable for the proposed experiments.

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Obaid, Najjat, Samir El Hadidy, Mahmoud El Badry i Hassan Khaled. "The Outcome of Diabetic Patients with Cardiomyopathy in Critical Care Unit: Hospital and Short-Term Outcome in a Period of Six Months to One Year". Open Access Macedonian Journal of Medical Sciences 7, nr 17 (12.08.2019): 2796–801. http://dx.doi.org/10.3889/oamjms.2019.655.

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BACKGROUND: Diabetes mellitus (DM) is a major risk factor for heart failure (HF) and coronary artery disease (CAD). DM may cause structural changes involving the left ventricle (LV) systolic and diastolic function. AIM: To compare patients who have diabetes and ischemic cardiomyopathy (ICM) to those with diabetic cardiomyopathy (DMCMP) regarding LV systolic function, diastolic function, in hospital long term and short-term mortality. METHODS: Ninety diabetic patients with heart failure and left ventricular ejection fraction (LVEF) ≤ 35%, admitted to Critical Care Medicine department Cairo University were divided into two groups based on coronary angiography results; group I (ICM) n = 48 patients and group II (DMCMP) n = 42 patients. RESULTS: Group I patients had higher mean age (63 ± 7 years), (p = 0.004), Hypertension (p ˂ 0.001) and dyslipidemia (p = 0.008) were significantly more present in group I compared to group II. No significant differences were found regarding LVEF, global longitudinal strain (GLS), E/A and E/É ratio in both groups. A significant difference in the wall motion score index (WMSI) in group I; (1.4 ± 0.4) versus group II; (1.1 ± 0.2), (p = 0.005) was found. In the study, 6 patients had a cardiogenic shock with no documented in-hospital mortality. At 6 months, statistically, significantly higher mortality rates were found in group I, (p = 0.006), while at one year there was no significant difference in the mortality between the two groups, (p = 0.077). In comparison of the survived and non-survived patients at 6 months and one year in group I (ICM) there was a significant difference in LVEF (40 ± 6% vs 23 ± 6%, p ˂ 0.001), GLS (- 8.1 ± 2.4 vs - 4.6 ± 2.6, p = 0.007), E/A (1.25 ± 0.91 vs 1.8 ± 0.5, p = 0.038), E/É (11.68 ± 7.5 vs 21.3 ± 3.6, p = 0.001) respectively. In group ll (DMCMP) there was no documented mortality at 6 months follow up, however, at one year there was statistically significant difference in the mortality between survived and non-survived patients; the LVEF (35 ± 8% vs 25 ± 2%, p = 0.014), GLS (-7.9 ± 2.9% vs -5 ± 0.1%, p = 0.032), E/A (1.45 ± 0.8 vs 3.3 ± 0, p = 0.006) respectively. The E/É ratio in group ll was not significantly different between the groups (15.73 ± 5.3 vs 15 ± 1, p = 0.873). CONCLUSION: The combination of cardiomyopathy and diabetes affects LV systolic and diastolic function; however; ischemic cardiomyopathy and diabetic cardiomyopathy had a similar systolic and diastolic function. Ischemic cardiomyopathy is associated with worse prognosis compared to diabetic cardiomyopathy.

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Toledo, Eduardo M., Andressa B. Siqueira, Tatiane V. Santosa, Fernanda S. Ribeiro, Ademir J. Camargo i Solemar S. Oliveira. "Estudo Teórico dos Parâmetros Estruturais da Cafeína no Vácuo Usando Dinâmica Molecular de Car-Parrinello". Revista Processos Químicos 11, nr 21 (2.01.2017): 17–24. http://dx.doi.org/10.19142/rpq.v11i21.388.

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A cafeína é uma das substâncias mais utilizadas no mundo. É classificada como um alcaloide que pertence ao grupo das metilxantinas (1,3,7 - timetilxantina). Está presente em várias plantas, é também encontrada nos chás, cacau, café, guaraná e refrigerantes. Quando consumida, afeta quase todos os sistemas, com seus efeitos mais perceptíveis no sistema nervoso central (SNC). Com essas propriedades biológicas observadas, o presente trabalho tem como objetivo estudar os comprimentos e ângulos de ligação da cafeína no vácuo, utilizando o método de Dinâmica Molecular de Car-Parrinello (DMCP). Para os cálculos, a molécula foi disposta em uma caixa cúbica, com aresta de 16 Å. O funcional de energia de troca e correlação foi modelado usando o funcional do gradiente corrigido PBE. Os elétrons do núcleo foram tratados com pseudopotenciais ultrasolf de Vanderbilt, e os de valência foram representados pelo conjunto de funções de base de ondas planas, truncadas em energia cinética de corte de 25 Ry. As simulações de DMCP foram realizadas a uma temperatura de 300 K, com um passo de integração de 5,0 a.t.u. (unidade atômica de tempo) e massa fictícia de 400 a.u. (unidade atômica). Os resultados obtidos para cálculos das propriedades estruturais utilizando DMCP mostram boa concordância com resultados obtidos por outros métodos teóricos e com dados experimentais. Este estudo contribui para a compreensão inicial das propriedades estruturais e da metodologia utilizada que é bastante promissora em estudos de planejamento de fármacos.

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Xiao, Han, Chao Zhang, Jiaojiao Zhao, Zhaohui Zheng i Yuehui Li. "Selective hydrogenation of dimethyl terephthalate over a potassium-modified Ni/SiO₂ catalyst". RSC Advances 13, nr 24 (2023): 16363–68. http://dx.doi.org/10.1039/d3ra02223d.

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Selective hydrogenation of DMT to DMCD was achieved a using KF-modified Ni/SiO2 catalyst. Doping only 0.5 wt% of KF by post-impregnation significantly improves the reactivity and selectivity (41% vs 95% conversion; 83% vs 96% selectivity).

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Zhang, Shuo, Chengning Zhang, Guangwei Han i Qinghui Wang. "Optimal Control Strategy Design Based on Dynamic Programming for a Dual-Motor Coupling-Propulsion System". Scientific World Journal 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/958239.

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A dual-motor coupling-propulsion electric bus (DMCPEB) is modeled, and its optimal control strategy is studied in this paper. The necessary dynamic features of energy loss for subsystems is modeled. Dynamic programming (DP) technique is applied to find the optimal control strategy including upshift threshold, downshift threshold, and power split ratio between the main motor and auxiliary motor. Improved control rules are extracted from the DP-based control solution, forming near-optimal control strategies. Simulation results demonstrate that a significant improvement in reducing energy loss due to the dual-motor coupling-propulsion system (DMCPS) running is realized without increasing the frequency of the mode switch.

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Sze, P. W., K. F. Yarn, Y. H. Wang, M. P. Houng i G. L. Chen. "Characteristics of MOCVD-Grown High-Quality CdTe Layers on GaAs Substrates". Active and Passive Electronic Components 18, nr 4 (1995): 247–58. http://dx.doi.org/10.1155/1995/16596.

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CdTe epitaxial layers are grown successfully on a (100)-GaAs substrate by metalorganic chemical vapor deposition (MOCVD) using dimethylcadrnium (DMCd) and diethyltelluride (DETe) as alkyl sources. The CdTe epilayers grown between 365°C and 380°C possess the best surface morphology. DETe is used as the controlling species of this growth system. Typical growth rates are varied from 2.51µm/hr to 5.31µm/hr. Low-temperature (12K) photoluminscence (PL) measurements reveal that 380°C is the best growth temperature and the full width at half maximum (FWHM) of the dominated peak is about 1.583eV by the bound-exciton emission of 9.38meV. The double crystal X-ray rocking curves (DCRC) indicate that the FWHM decreases while increasing the epilayer thickness and approaches a stable value about 80 arc sec under the growth rate of 5.2µm/hr, the growth temperature of 380°C and the DETe/DMCd concentration ratio of 1.7. The value of 80 arc sec in FWHM is the smallest one ever reported to date.

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Sigrist, Stephan, Gabriele Ried i Christian F. Lehner. "Dmcdc2 kinase is required for both meiotic divisions during Drosophila spermatogenesis and is activated by the Twine/cdc25 phosphatase". Mechanisms of Development 53, nr 2 (październik 1995): 247–60. http://dx.doi.org/10.1016/0925-4773(95)00441-3.

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Bonfiglioli, Karina. "Cuidados para prescrição de biológicos: atualizações no rastreamento e seguimento com ênfase no risco infeccioso". Revista Paulista de Reumatologia, nr 2017 jan-mar;16(1) (31.03.2017): 6–9. http://dx.doi.org/10.46833/reumatologiasp.2017.16.1.6-9.

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As recomendações de segurança no manejo de medicamentos imunobiológicos estão em constante reformulação, acompanhando a experiência cumulativa crescente das grandes coortes e estudos de registro. Sumarizamos, a seguir, as recomendações mais atualizadas para o rastreamento e seguimento de eventos infecciosos na vigência do tratamento com drogas modificadoras do curso da doença (DMCD) biológicas em doenças reumáticas.

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Nimroody, Tehela, Leon Hoffman, Christopher Christian, Timothy Rice i Sean Murphy. "Development of a Defense Mechanisms Manual for Children’s Doll Play (DMCP)". Journal of Infant, Child, and Adolescent Psychotherapy 18, nr 1 (2.01.2019): 58–70. http://dx.doi.org/10.1080/15289168.2018.1565005.

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Soliz, Jennifer R., Smriti Ranjit, Joshua J. Phillips, Richard A. Rosenberg i Adam J. Hauser. "Magnetic and Impedance Analysis of Fe2O3 Nanoparticles for Chemical Warfare Agent Sensing Applications". Magnetochemistry 9, nr 9 (25.08.2023): 206. http://dx.doi.org/10.3390/magnetochemistry9090206.

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A dire need for real-time detection of toxic chemical compounds exists in both civilian and military spheres. In this paper, we demonstrate that inexpensive, commercially available Fe2O3 nanoparticles are capable of selective sensing of chemical warfare agents (CWAs) using frequency-dependent impedance spectroscopy, with additional potential as an orthogonal magnetic sensor. X-ray magnetic circular dichroism analysis shows that Fe2O3 nanoparticles possess moderately lowered moment upon exposure to 2-chloroethyl ethyl sulfide (2-CEES) and diisopropyl methylphosphonate (DIMP) and significantly lowered moment upon exposure to dimethyl methylphosphonate (DMMP) and dimethyl chlorophosphate (DMCP). Associated X-ray absorption spectra confirm a redox reaction in the Fe2O3 nanoparticles due to CWA structural analog exposure, with differentiable energy-dependent features that suggest selective sensing is possible, given the correct method. Impedance spectroscopy performed on samples dosed with DMMP, DMCP, and tabun (GA, chemical warfare nerve agent) showed strong, differentiable, frequency-dependent responses. The frequency profiles provide unique “shift fingerprints” with which high specificity can be determined, even amongst similar analytes. The results suggest that frequency-dependent impedance fingerprinting using commercially available Fe2O3 nanoparticles as a sensor material is a feasible route to selective detection.

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Shaw, Ping S., Esaul Sanchez, Zhen Wu i Richard M. Osggod. "A UV spectroscopic study of DMZn and DMCd chemisorbed on quartz surfaces". Chemical Physics Letters 151, nr 4-5 (październik 1988): 449–54. http://dx.doi.org/10.1016/0009-2614(88)85167-4.

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Arrais-Castro, A., Maria Leonilde Rocha Varela, G. D. Putnik, Rita Ribeiro i F. C. C. Dargam. "Collaborative Negotiation Platform using a Dynamic Multi-Criteria Decision Model". International Journal of Decision Support System Technology 7, nr 1 (styczeń 2015): 1–14. http://dx.doi.org/10.4018/ijdsst.2015010101.

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Due to globalization, companies are frequently pushed to grow outside their political and geographical boundaries, forcing them to increase product diversification. As a side effect they can also optimize their resource's management by looking at potential businesses for improving their relations with customers and/or open new markets through partnerships. In this context, implementing agile collaboration networks between businesses is a requirement. This paper proposes an approach to support the selection of businesses in the context of collaborative-networked organizations, through a negotiation process controlled by agents, which is based on a dynamic multi-criteria decision model (DMCDM). The approach combines a dynamic decision making approach - using past, current and future information - with a software agents approach, which autonomously captures business opportunities, select business partners, as well as award and process associated orders. An illustrative example of evaluation and selection of business partners clarifies the dynamic method.

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Hu, Guoyi, i Shuichang Zhang. "Characterization of Low Molecular Weight Hydrocarbons in Jingbian Gas Field and its Application to Gas Sources Identification". Energy Exploration & Exploitation 29, nr 6 (grudzień 2011): 777–95. http://dx.doi.org/10.1260/0144-5987.29.6.777.

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Chemical and isotopic compositions of C6-C7 low molecular weight hydrocarbons (LMWHs) were used to determine the origin of gas in the Ordovician weathered crust (O1m5) reservoir of Jingbian gas field in Ordos Basin, China. GC quantification of LMWHs for 55 gas samples [20 of them from the Xiashihezi Formation (P1x) and Shanxi Formation (P1s) reservoirs, and the rest from the O1m5 reservoir] were conducted. The compound specific stable carbon isotopes of LMWHs for 24 gas samples (five gas samples from the P1s reservoir) were analyzed with GC-C-IRMS. The results show that cycloalkanes are abundant components and their concentrations range from 23.8–52.5% with an average of 41.1% among LMWHs. Methylcyclohexane (MCH) is the most abundant one among normal heptane ( n-C7), MCH and dimethylcyclopentane (DMCP), ranging from 50.1–81.4% with an average value of 71.6%. A13C enrichment for nine compounds of C6-C7 fraction was observed, and the δ13C values range from −25.4–16.3%. Based on the correlation of the Mango parameters (K1 and K2), the relationship of n-C7, MCH and DMCP and compound specific carbon isotope of C6-C7 compounds, the gas in the O1m5 reservoir shares the same origin with that in the P1x, P1s reservoirs, the natural gas in Ordovician weathered crust reservoir and Permian sandstone reservoir sourced from coal measures in Carboniferous and Permian.

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Diener, Andrew C., i Gerald R. Fink. "DLH1 is a Functional Candida albicans Homologue of the Meiosis-Specific Gene DMC1". Genetics 143, nr 2 (1.06.1996): 769–76. http://dx.doi.org/10.1093/genetics/143.2.769.

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Abstract DMC1/LIM15 homologue 1 (DLH1), a gene related to meiosis-specific genes, has been isolated from Candida albicans, a fungus thought not to undergo meiosis. The deduced protein sequence of DLH1 contains 74% amino acid identity with Dmclp from Saccharomyces cermisiae and 63% with Liml5p from the plant Lilium long)lmm, meiosisspecific homologues of Escherichia coli RecA. Candida DLH1 complements a dmcl/dmcl null mutant in S. cermisiae: High copy expression of DLH1 restores both sporulation and meiotic recombination to a Saccharomyces dmclΔ/dmclΔ strain. Unlike the DMCl gene, which is transcribed only in meiotic cells, the heterologous Candida DLH1 gene is transcribed in both vegetative and meiotic cells of S. cermisiae. Transcription of DLH1 is not detected or induced in C. albicans under conditions that induce DMC1 and meiosis in S. cermisiae. The presence of an intact homologue of a meiosis-specific gene in C. albicans raises the possibility that this organism has a cryptic meiotic pathway.

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Kateneva, Anna V., Anton A. Konovchenko, Vincent Guacci i Michael E. Dresser. "Recombination protein Tid1p controls resolution of cohesin-dependent linkages in meiosis in Saccharomyces cerevisiae". Journal of Cell Biology 171, nr 2 (17.10.2005): 241–53. http://dx.doi.org/10.1083/jcb.200505020.

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Sister chromatid cohesion and interhomologue recombination are coordinated to promote the segregation of homologous chromosomes instead of sister chromatids at the first meiotic division. During meiotic prophase in Saccharomyces cerevisiae, the meiosis-specific cohesin Rec8p localizes along chromosome axes and mediates most of the cohesion. The mitotic cohesin Mcd1p/Scc1p localizes to discrete spots along chromosome arms, and its function is not clear. In cells lacking Tid1p, which is a member of the SWI2/SNF2 family of helicase-like proteins that are involved in chromatin remodeling, Mcd1p and Rec8p persist abnormally through both meiotic divisions, and chromosome segregation fails in the majority of cells. Genetic results indicate that the primary defect in these cells is a failure to resolve Mcd1p-mediated connections. Tid1p interacts with recombination enzymes Dmc1p and Rad51p and has an established role in recombination repair. We propose that Tid1p remodels Mcd1p-mediated cohesion early in meiotic prophase to facilitate interhomologue recombination and the subsequent segregation of homologous chromosomes.

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Ji, Hong-Kun, Quan-Sen Sun, Yun-Hao Yuan i Ze-Xuan Ji. "C 2 DMCP: View-consistent collaborative discriminative multiset correlation projection for data representation". Journal of Visual Communication and Image Representation 40 (październik 2016): 393–405. http://dx.doi.org/10.1016/j.jvcir.2016.06.012.

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Wu, Yi Yi, Xiao Gang Yang, Xiao Bing Huang, Vincent Barrioz, Shafiul Monir, Stuart Irvine i Giray Kartopu. "CFD Modelling of Cadmium Telluride (CdTe) Thin Film Coating with Inline AP-MOCVD". Applied Mechanics and Materials 217-219 (listopad 2012): 1265–73. http://dx.doi.org/10.4028/www.scientific.net/amm.217-219.1265.

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A CFD numerical model has been established to study the growth of cadmium telluride (CdTe) on substrate using metalorganic chemical vapour deposition technique in atmospheric pressure (AP-MOCVD) and hydrodynamics in an inline MOCVD reactor. The numerical simulations have been conducted using the CFD code – ANSYS Fluent. Dimethylcadmium (DMCd) and diisopropyltelluride (DIPTe) have been employed as precursors while H2 is acting as the carrier gas. In order to assess the effect of various conditions on CdTe film growth and uniformity, heat transfer and mass transport behaviours of the chemical species in the reactor have been fully investigated. In addition, material utilization and fluid dynamics in the reactor are also discussed.

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Fukuda, Tomoyuki, i Yoshikazu Ohya. "Recruitment of RecA homologs Dmc1p and Rad51p to the double-strand break repair site initiated by meiosis-specific endonuclease VDE (PI-SceI)". Molecular Genetics and Genomics 275, nr 2 (9.12.2005): 204–14. http://dx.doi.org/10.1007/s00438-005-0078-4.

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Ebrahim, Amani M., Anna M. Plonka, Ning Rui, Sooyeon Hwang, Wesley O. Gordon, Alex Balboa, Sanjaya D. Senanayake i Anatoly I. Frenkel. "Capture and Decomposition of the Nerve Agent Simulant, DMCP, Using the Zeolitic Imidazolate Framework (ZIF-8)". ACS Applied Materials & Interfaces 12, nr 52 (17.12.2020): 58326–38. http://dx.doi.org/10.1021/acsami.0c12985.

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Brankovic, Zorica, Goran Brankovic, Dejan Poleti, Ljiljana Karanovic i Jose Varela. "Correlation between chemical composition of the γ-Bi2O3 phase and the properties of ZnO varistors". Chemical Industry and Chemical Engineering Quarterly 11, nr 4 (2005): 169–72. http://dx.doi.org/10.2298/ciceq0504169b.

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Four varistor samples differing in chemical and phase composition of the starting Bi2O3 phase were prepared by the method of direct mixing of the constituent phases (DMCP), i.e. by sintering the mixture of the previously prepared phases. The compositions of the constituent phases in the sintered samples were investigated by changes of their lattice constants and by EDS analysis. After sintering, the phase compositions of all the investigated samples were the same: ZnO phase, spinel and ?-Bi2O3. It was found that the ?-Bi2O3 phase was mainly stabilized with Zn2+ ions. All the samples showed good electrical properties with non-linearity coefficients up to 50 and small values of the leakage current. The electrical properties of the samples were discussed in terms of diffusion processes and the redistribution of additives during sintering.

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Pettus, Thomas, Todd Wenderski i Vincent DeNatale. "Synthesis of 2,2-Disubstituted Pentalenes and Indenes by a Useful Modification to Nakamura’s DMCP [3+2]-Cycloaddition Protocol". Synlett 2009, nr 16 (4.09.2009): 2637–42. http://dx.doi.org/10.1055/s-0029-1217755.

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