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Fastrez, Maxime. "Minimal-invasive management of deep infiltrating endometriosis: diagnosis and treatment". Doctoral thesis, Universite Libre de Bruxelles, 2018. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/271669.
Pełny tekst źródłaDoctorat en Sciences médicales (Médecine)
info:eu-repo/semantics/nonPublished
Borrelli, Giuliano [Verfasser]. "Investigation of invasion factors in deep-infiltrating endometriosis / Giuliano Borrelli". Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2015. http://d-nb.info/1079524592/34.
Pełny tekst źródłaPhilip, Charles-André. "Description, évaluation et perfectionnement d’une nouvelle technique de prise en charge de l'endométriose profonde postérieure recto-sigmoïdienne par ultrasons focalisés de haute intensité (HIFU) échoguidés par voie transrectale". Electronic Thesis or Diss., Lyon, 2020. http://www.theses.fr/2020LYSE1065.
Pełny tekst źródłaOBJECTIVES: In this thesis we describe a new technique for the management of rectosigmoid endometriosis by transrectal ultrasound-guided high intensity focused ultrasound ultrasound (TR-USgHIFU). We also review several limiting factors of this technique before assessing several modifications to improve the feasibility and the efficacy of the procedure. METHODS: We first conducted a phase I clinical trial to test the feasibility of TR-USgHIFU treatment using the FocalOne® device. We then carried out a study on anatomical specimens to assess the limiting factors of the FocaleOne® probe and to test another HIFU probe, which has smaller transducer and which is mounted on a flexible endoscope. We also performed an observational clinical study to measure the acoustic attenuation of rectosigmoid endometriosis lesions and that of normal bowel. Finally, we have developed a murine model of subcutaneous endometriosis to assess the pathophysiological effects of HIFU on endometriosis. RESULTS: We included 23 patients in the phase I clinical trial between June 2015 and October 2019. Treatment was carried out in 20 of these patients (87% feasibility). No serious adverse events have been reported. We did not find a significant morphological effect at 6 months, but we report a significant improvement on digestive and gynecological symptoms as well as on patients’ quality of life. Studies on anatomical specimens and on MRI pictures demonstrated the role of the sacrum and the recto-sigmoid hinge in the mechanical limitations of the FocalOne® probe. The use of a smaller probe with a shorter focal could be interesting in order to increase the feasibility of the treatment. Our study on 13 patients treated surgically for rectum or sigmoid endometriosis nodule, showed that attenuation of digestive endometriosis at 3 MHz is 50.2 Np / m. This value was significantly higher than attenuation of the normal bowel (32.8; p <0.001). We finally showed that the heterologous subcutaneous murine model "BALB / c-nude # Ishikawa" was reliable and efficient to study the effects of HIFU on digestive endometriosis, as the acoustic attenuation of its nodules are remarkably close to that of endometriosis lesions. Thanks to this model, we reported that HIFU lesions are associated with a higher rate of ischemic and coagulation necrosis. CONCLUSIONS: Treatment with TR-USgHIFU in rectosigmoid endometriosis is feasible and safe. Its morphological efficacy remains to be demonstrated, but its significant clinical efficacy is promising. It could become be a minimally invasive alternative to replace surgical treatment in this indication, especially for rectal lesions
Anaf, Vincent. "Contribution to the physiopathology, symptomatology and treatment of deep infiltrating endometriosis". Doctoral thesis, Universite Libre de Bruxelles, 2004. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/211116.
Pełny tekst źródłaDoctorat en sciences médicales
info:eu-repo/semantics/nonPublished
Ruge, Diane. "Deep brain stimulation-mediated and non-invasive modulation of neuronal circuits". Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1471231/.
Pełny tekst źródłaAli, Laila. "Endometriosis and the lympathic system: lymph nodes draining the uterus and deep infiltrating endometriotic lesions of the bowel". Thesis, The University of Sydney, 2015. http://hdl.handle.net/2123/12638.
Pełny tekst źródłaPloteau, Stéphane. "Etude du lien entre l’exposition aux polluants organiques persistants et l’endométriose". Thesis, Nantes, Ecole nationale vétérinaire, 2016. http://www.theses.fr/2016ONIR087F/document.
Pełny tekst źródłaEndometriosis is a gynecological disease for whichexposure to some environmental chemicals is evocatedamong the associated risk factors. Epidemiological studies are however globally non convergent and finally fairly conclusive. Their heterogeneity in terms of lesion localization and sub-phenotype, methodology, size and nature of the populations studied, as well as the limited number of monitored markers of exposure contribute to this situation. We realized a matched case-control study based on a biocollection of 113 patients including 68 patients suffering of deep endometriosis and 45 controls. We characterized the internal exposure levels of an extended range of around 78 persistent organic pollutants (including dioxins, polychlorobiphenyls, brominated flame retardants and organochlorine pesticides). Internal level exposures were measured in three biological compartments (omental fat, subcutaneous fat and serum). First, the distribution of these chemicals was characterized within these compartments. These extended exposure data from deep infiltrating endometriosis patients are the first ones available for France and give a new insight about the equilibrium of chemicals between storage and circulating compartments that should be further considered as a potential indicator permitting to establish a possible association between a chronic exposure to chemical hazards and human pathology. Afterwards, some of the targeted chemicals appeared significantly associated with deep endometriosis. A sub-stratification of our case population indicated a more significant relationship with the presence of endometrioma. Underlying mechanisms remain to be determined
Lamp, Julika. "Etablierung nicht invasiver Testsysteme zur Darstellung von Beeinträchtigungen und Schmerzen in einem Primatenmodell für Endometriose". Doctoral thesis, Universitätsbibliothek Leipzig, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-61348.
Pełny tekst źródłaEndometriosis (EM) is a common gynecological disease, which is known to cause chronic pelvic pain and infertility in women (VALLE 2002). Up to now, it was not possible to assess, whether the animal models for research (e.g. rhesus macaque, ZONDERVAN et al. 2004; common marmoset, EINSPANIER et al. 2006) suffer from pain or impairments due to the disease. Therefore, new test systems are needed to obtain pain and discomfort in animal models for EM to enable the validation of new therapeutic agents with a view to the patients well being. It was the aim of this study, to establish new non invasive test systems to investigate signs of discomfort in an animal model for EM, the marmoset monkey. Assuming that painful diseases can influence the behaviour (WALLACE et al. 1990), the mobility (FLECKNELL 1986) and the cognitive abilities (SMITH et al. 2006) of animals, three non invasive test systems were reviewed for their ability to detect EM associated pain in common marmosets. They were based on behaviour (videotaping), mobility and exploratory behaviour (food tree, modified after ROBERTS et al. 1993) and cognitive abilities (Wisconsin General Test Apparatus (HARLOW 1949) and food tree). In the first part of this study, the daily activity patterns, allo- and autogrooming as well as water and food intake of nine common marmoset couples were monitored over a 12-hour light phase by video recording. The animals showed a trimodal course of activity per day with maxima from 7:00-8:00h, 11:00-12:00h and 15:00-16:00h. These activity maxima represented foraging behaviour, as they were followed by frequent food intake phases. The knowledge of the daily activity patterns allowed to optimize the experimental conditions for the tasks with the food tree and the Wisconsin General Test Apparatus (WGTA; HARLOW 1949) in the second part of this study. As every animal solved the tasks at the same time of day, the comparability and homogeneity of the results were optimized. By analysing the video documentation in the second part of this study, the females with EM, in contrast to the control females, did not show any social grooming behaviour (p=0.029). Furthermore, their activity level was almost significantly decreased (p=0.057). This reduced activity could indicate towards pain in the diseased females, while the lack of social grooming is similar to partnership problems in diseased women. The WGTA tasks revealed, that the females with EM performed significantly less trials per day in the first two settings (p=0.006/ p=0.008) and needed more trials to solve the first setting than the control animals (p=0.008). Those differences between diseased females and control animals were not detectable in the following three settings of the WGTA tasks. These results demonstrate, that EM affected marmosets have difficulties to concentrate on cognitive tasks and to cope with new situations. According to the International Primatological Society (MC CANN et al. 2007), these difficulties to cope with new situations can be interpreted as signs of distress. The food tree, a kind of jungle gym, was used to assess the animals` cognitive abilities as well as their mobility, but there were no significant differences between the EM diseased females and the control animals. In conclusion, the videotaping and the WGTA are suitable methods to demonstrate signs for impairments due to EM in marmoset monkeys. In following pharmacological studies, both test systems will allow to evaluate the benefit of new therapeutic agents on the animal model`s well being. In addition, the results of this study can help to refine procedures by replacing invasive methods like laparotomy according to the Refinement of RUSSELL and BURCH (1959)
Daum, Douglas R. 1968. "A large scale phased array ultrasound system for non-invasive surgery of deep seated tissue". Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/85261.
Pełny tekst źródłaIncludes bibliographical references (leaves 229-239).
by Douglas R. Daum.
Ph.D.
Pitman, Jeremy David. "Non-invasive detection of the electromyographic activity of the deep extrinsic thumb muscles using surface electrodes". Master's thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/16783.
Pełny tekst źródłaMotivation: Conventional surface electromyography (EMG) methods cannot be used to detect deep muscle activation. A new non-invasive superficial and deep muscle EMG (sdEMG) technique has recently been used to derive the EMG activity of Brachialis and Tibialis Posterior muscles in the upper and lower limb respectively. The aim of the present study was to apply a modified version of sdEMG to the forearm to detect EMG activity of the deep extrinsic thumb muscles Flexor Pollicis Longus (FPL), Extensor Pollicis Longus (EPL), Extensor Pollicis Brevis (EPB) and Abductor Pollicis Longus (APL) using surface electrodes. Methods: High density monopolar EMG was detected from 2 concentric rings, each consisting of 20 custom designed and manufactured silver electrodes, placed at the distal and proximal thirds of the right forearm of 15 healthy male participants. The EMG signals were recorded by a custom synthesised from open source components, EMG amplifier system interfacing with a custom designed LabVIEW® program. The participants performed 10 repetitions of isometric thumb flexion (TFl), thumb extension (TEx), thumb abduction (TAb), thumb adduction (TAd), index finger flexion (IFFl) and index finger extension (IFEx). Each isometric contraction was performed in a randomized order at a standardized effort level of 30% of the participant's maximum voluntary contraction (verified by a custom designed and built thumb dynamometer). The Independent Component Analysis (ICA) algorithm, fastICA, was used to un-mix the 40 monopolar EMG waveforms (containing EMG activity attributable to both superficial and deep muscles) into 40 constitutive components, known as the Independent Components (ICs). The activation envelope of the ICs was found using a 250ms RMS smoothing filter and normalized between 0 and 1. A contraction sequence specific predicted EMG waveform based on intramuscular measurements (from existing studies in the literature) was created for each deep muscle and correlated with the processed ICs using Pearson's Correlation Coefficient (r). The ICs were ranked according to the corresponding r value and the highest r ranked IC for each muscle was considered to represent the recovered EMG activity from that particular muscle. Finally, a per sample basis accuracy, sensitivity and specificity analysis was conducted between each deep muscle's predicted EMG and highest r ranked IC at different activation thresholds. A linear mixed-effects statistical model was used to find the overall accuracy, sensitivity and specificity values over all the thresholds for each deep muscle. Results: Overall correlations of 0.81 for FPL (D), 0.88 for EPL (D), 0.92 for EPB (D) and 0.83 for APL (D) (p<0.001 for all muscles) were found between the predicted EMG waveforms and ICs. Using an activation threshold of 3 standard deviations above a resting baseline level, statistically significant (p<0.001) accuracy, sensitivity and specificity measures were found between the predicted EMG waveforms and top r ranked ICs for each of the deep muscles. The values of the 3 statistical measures (accuracy, sensitivity, specificity) for each of the deep muscles were: FPL (0.76, 0.88, 0.70); EPL (0.87, 0.85, 0.91); EPB (0.94, 0.93, 0.94); APL (0.80, 0.87, 0.87). Conclusions: The results indicate that this is the first non-invasive detection of the EMG activity of FPL (D), EPL (D), EPB (D) and APL (D). The ability to detect movement intention as a result of activation from these muscles may be of use for robot based targeted rehabilitation of the hand or in the control of prosthetic hand devices.
Pagliazzi, Marco. "Time domain, near-infrared diffuse optical methods for path length resolved, non-invasive measurement of deep-tissue blood flow". Doctoral thesis, Universitat Politècnica de Catalunya, 2019. http://hdl.handle.net/10803/667682.
Pełny tekst źródłaLa medición no invasiva y, a menudo, continua de la hemodinámica del cuerpo, y para los propósitos principales de esta tesis, del cerebro, es conveniente porque tanto los valores instantáneos como sus variaciones en el tiempo se adaptan constantemente a las condiciones que afectan el cuerpo humano y su entorno. Estas suelen alterarse en situaciones patológicas o como respuesta a una mayor función. Es deseable que estas mediciones sean continuas, confiables, mínimamente invasivas y relativamente asequibles. En los últimos años, las técnicas ópticas que, mediante el uso de luz difusa para medir los tejidos en profundidad (hasta unos pocos centímetros) mediante niveles de intensidad que son seguros para la piel, combinan las características arriba mencionadas, se han utilizado cada vez más tanto en entornos clínicos como de investigación. Sin embargo, al día de hoy hay, por un lado, la necesidad de ampliar el número y el ámbito de los estudios translacionales y, por el otro, de suplir a las deficiencias como por ejemplo la contaminación de volúmenes de tejido no deseados (efectos de volumen parcial). Otro objetivo importante es aumentar la profundidad de penetración de la luz sin afectar la naturaleza no invasiva de la óptica difusa. Mi doctorado está destinado a mejorar varios aspectos de este problema; (i) el desarrollo de nuevos métodos más avanzados, es decir, el método resuelto en el tiempo/trayectoria de los fotones, para mejorar la diferenciación entre los tejidos superficiales y profundos, (ii) la exploración de nuevas áreas de aplicación, es decir, para caracterizar el estado microvascular de los huesos, para estudiar la respuesta funcional del cerebro en los niños, y (iii) para mejorar el control de calidad de los sistemas, es decir, mediante la introducción de un phantom dinámico de larga vida útil. En orden conceptual, primero voy a introducir estándares de referencia de larga vida útil para la espectroscopia de correlación difusa (DCS). En segundo lugar, voy a describir el uso de un sistema híbrido espectroscopia tiempo-resuelta (TRS) con DCS ya existente para monitorizar los cambios que algunas condiciones patológicas, en este caso la osteoporosis y la infección por el virus de la inmunodeficiencia humana, pueden comportar para muchos aspectos del tejido óseo humano que actualmente no se pueden medir con facilidad (es decir, se van evaluado de forma invasiva) mediante técnicas convencionales. En tercer lugar, voy a describir el desarrollo de una novedosa técnica óptica en el dominio temporal que combina íntimamente, introduciendo muchos avances previamente no cumplidos, TRS y DCS. Por primera vez pude producir un dispositivo y un protocolo tiempo-resueltos para medir el flujo de la sangre en la cabeza y en los músculos de seres humanos sanos. Por último, en esta tesis voy a describir un dispositivo y un método que he usado para monitorear los cambios en el flujo sanguíneo como marcadores de activación del cerebro debida a estímulos visivos en bebés entre tres y cinco meses de edad. En general, este trabajo amplia los limites de la tecnología que hace uso de la luz difusa para monitorizar, de forma mínimamente invasiva, continua y confiable los marcadores endógenos de procesos patológicos y fisiológicos en el cuerpo humano.
Brijlal, Yasheen. "Development and Validation of Experimental Protocol and Guidelines for Non-Invasive Superficial and Deep Muscle Electromyography in the Forearm". Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29502.
Pełny tekst źródłaZhang, Lichang. "Non-invasive detection algorithm of thermal comfort based on computer vision". Thesis, KTH, Skolan för elektroteknik och datavetenskap (EECS), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-241082.
Pełny tekst źródłaSlöseriet med att bygga energiförbrukningen är en stor utmaning i världen. Ochdetektering av mänsklig termisk komfort i realtid är ett effektivt sätt att lösaproblemet. Som nämns i namn betyder det att detektera människans komfortnivå i realtid och icke-invasivt. På grund av de olika faktorerna som individuell skillnad i termisk komfort, är emellertid faktorer som är relaterade till klimat (temperatur, luftfuktighet, belysning etc.) det fortfarande en lång väg att implementera denna strategi i verkligheten. Från ett annat perspektiv kan nuvarande system för uppvärmning, ventilation och luftkonditionering inte tillhandahålla flexibla interaktionskanaler för att anpassa atmosfären och naturligtvis misslyckas till nöjda krav från användarna. Alla indikerar nödvändigheten av att utveckla en detekteringsmetod för mänsklig termisk komfort. I detta dokument föreslås en ickeinvasion detekteringsmetod mot mänsklig termisk komfort från två perspektiv: makro mänskliga hållningar och hudtexturer. I hållningspartiet används OpenPose för att analysera positionskoordinaterna för kroppens huvudpunkter i bilder, till exempel armbåge, knä och höftben osv. Och resultaten av analysen skulle tolkas från termen av termisk komfort. I hudtexturer används djupt neuralt nätverk för att förutse temperaturen på mänskliga skinn via bilder. Baserat på Fangers teorin om värmekomfort är resultaten av båda delarna tillfredsställande: subjektens hållningar kan fångas och tolkas till olika värmekomfortnivåer: varm, kall och komfort. Och det absoluta felet av prediktering från neuronnätverket är mindre än 0,125 grader Celsius, vilket är utrustningsfelet hos termometern som används vid datainsamling. Med lösningar i detta papper är det lovande att detektera användarens värmekomfortnivå fritt från invändningar och hudtexturer. Slutligen diskuteras slutsatserna och detframtida arbetet i sista kapitlet.
Islam, Naimul. "The potential for using combined electrical impedance and ultrasound measurements for the non-invasive determination of temperature in deep body tumours during mild hyperthermia". Thesis, University of Warwick, 2012. http://wrap.warwick.ac.uk/56721/.
Pełny tekst źródłaMira, Ticiana Aparecida Alves de 1986. "Estimulação elétrica nervosa transcutânea (TENS) no tratamento complementar da dor em mulheres com endometriose profunda = Transcutaneous electrical nerve stimulation (TENS) applied to complementary treatment of the pain in women with deep endometriosis". [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/312559.
Pełny tekst źródłaDissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas
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Resumo: Introdução: Apesar dos tratamentos cirúrgico e medicamentoso utilizados para endometriose, muitas mulheres mantêm os sintomas álgicos. A literatura é escassa quanto a tratamentos complementares para dor. Objetivos: Avaliar a efetividade da TENS no tratamento complementar da dor pélvica crônica e dispareunia de profundidade em mulheres com endometriose profunda. Sujeitos e métodos: Ensaio controlado aleatorizado realizado no Departamento de Tocoginecologia da Universidade Estadual de Campinas. Foram incluídas 22 mulheres com endometriose profunda em uso de tratamento hormonal (progestagênios ou contraceptivo oral combinado), com persistência da queixa de dor pélvica crônica e/ou dispareunia de profundidade. Realizou-se aplicação da TENS por 8 semanas, com aleatorização das participantes em dois grupos: Grupo 1 - TENS modo acupuntura (Frequência: 8Hz, duração do pulso: 250µs e variação em intensidade e frequência (VIF) em 1ms) (n=11) e Grupo 2 - TENS autoaplicável (Frequência: 85Hz, duração do pulso: 75µs) (n=11); intensidade: ajustável "forte, mas confortável". Foram realizadas avaliações pré e pós-tratamento através da Escala Visual Analógica, Escala de Dispareunia de Profundidade, Questionário de Qualidade de Vida em Endometriose (EHP-30). Comparação pré e pós-tratamento através de teste de Wilcoxon e teste de Mann-Whitney. Resultado: As 22 mulheres com endometriose profunda utilizavam tratamento hormonal há 1,65±2,08 anos e mantinham queixa de dor pélvica e/ou dispareunia de profundidade. Os dois tipos de TENS, modo acupuntura e autoaplicável, promoveram melhora da dor pélvica crônica (p<.0001), dispareunia de profundidade (p=.0010) e qualidade de vida (p<.0001). Conclusões: Ambos os recursos (TENS modo acupuntura e TENS autoaplicável) demonstraram efetividade no tratamento complementar da dor pélvica crônica e dispareunia de profundidade e melhora da qualidade de vida de mulheres com endometriose profunda, independente do dispositivo utilizado para tratamento
Abstract: Introduction: Despite all the surgical and medical treatments for endometriosis many women have symptoms of pain. Nevertheless, the literature is scarce on additional treatments for pain. Objective: Evaluate the effectiveness of TENS applied as a complementary treatment of chronic pelvic pain and deep dyspareunia in women with deep endometriosis. Subjects and Methods: Randomized controlled trial conducted at the Department of Obstetrics and Gynecology of the University of Campinas. Twenty-two women were included and they presented deep endometriosis and made use of hormonal treatment (progestin or combined oral contraceptive) with persistent complaints of chronic pelvic pain and/or deep dyspareunia. TENS application for 8 weeks was applied with randomization of participants into two groups: Group 1 - TENS like acupuncture (frequency: 8 Hz, pulse duration: 250?s and variation in intensity and frequency (VIF) of 1 ms) (n = 11) and Group 2 - TENS self-applied (frequency: 85Hz, pulse duration: 75?s) (n = 11); intensity: Adjustable "strong but comfortable". Measurements by Visual Analogue Scale, Dyspareunia Depth Scale and Endometriosis Health Profile - Questionnaire (EHP-30) were performed pre and post treatment. To compare pre and post-treatment the Wilcoxon test and Mann-Whitney test were used. Results: The twenty-two women with deep endometriosis used hormonal treatment for 1.65±2.08 years and kept complaining about pelvic and / or deep dyspareunia pain. The two types of TENS (acupuncture and self-applied) promoted improvement in chronic pelvic pain (p <.0001), deep dyspareunia (p = .0010) and quality of life (p <.0001). Conclusion: Both features (TENS like acupuncture and TENS self-applied) demonstrated effectiveness as complementary treatment of chronic pelvic pain and deep dyspareunia and improved the quality of life of women with deep endometriosis regardless which one of the devices were used for treatment
Mestrado
Fisiopatologia Ginecológica
Mestra em Ciências da Saúde
Mendonça, Juliana Vieira de. "Qualidade da imagem nas pacientes com suspeita de Endometriose infiltrada profunda : comparação entre a ultrassonografia transvaginal antes e após a realização do preparo retal". Universidade do Estado do Rio de Janeiro, 2011. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=5890.
Pełny tekst źródłaTo compare image quality between the transvaginal ultrasound without bowel preparation and after bowel preparation in patients with suspected deep infiltrating endometriosis of the posterior compartment and evaluate the degree of discomfort of patients in relation to bowel preparation. Cross sectional data collected prospectively, including 39 patients with clinical suspicion of endometriosis of the posterior compartment of the endometriosis clinic of the Hospital Universitário Pedro Ernesto (HUPE) State University of Rio de Janeiro (UERJ), in Rio de Janeiro . The patients underwent transvaginal sonography (USTVG) without prior bowel preparation, followed by new USTVG one hour after completion of the rectal enema. The recorded videos of the tests were published, with emphasis on evaluation of the posterior compartment, with interest in the identification of the nodule retrocervical and rectosigmoid. Were graded according to the quality of the image by the examiner and by a radiologist (both masked), which marked a score from 0 to 10, using the visual analog scale. That left only 26 patients. Regarding the realization of discomfort due to rectal enema, all patients (100%) reported only mild discomfort. Depending on the option chosen by the evaluators regarding the best method, they agreed in 13 (50%) patients with transvaginal ultrasound rectal preparation is better. We used the nonparametric Wilcoxon test for dependent samples. The p-value obtained was 0042 and considered significant (less than 0.05). This means that the completion of rectal enema prior to the transvaginal ultrasound provided a better quality in the evaluation of nodules. The difference between evaluations with and without rectal preparation is higher in nodules smaller than 2 cm, because we found a difference of 1.1 between the median values of the two types of tests. In nodules larger than 2cm, the difference was only 0.65. The performance of the rectal enema prior to the performance of transvaginal sonography in the diagnosis of endometriotic nodule shows a slightly significant improvement in image quality, compared to non-completion of bowel preparation prior. Only in cases where the lump was less than 2 cm were found statistically significant values with rectal preparation. The rectal enema cause mild discomfort, but this does not seem to be a limiting factor in the performance of ultrasound with bowel preparation
Antico, Maria. "4D ultrasound image guidance for autonomous knee arthroscopy". Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/211437/1/Maria_Antico_Thesis.pdf.
Pełny tekst źródłaLeconte, Mahaut. "Etude phénotypique des cellules endométriosiques profondes". Phd thesis, Université René Descartes - Paris V, 2012. http://tel.archives-ouvertes.fr/tel-00832636.
Pełny tekst źródłaZanatta, Alysson. "Expressão proteíca do gene HOXA10 e dos receptores de estrogênio e progesterona no epitélio, estroma e tecido muscular liso perilesional de endometriose e do reto-sigmoide". Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/5/5139/tde-06112013-085759/.
Pełny tekst źródłaINTRODUCTION: Although deep endometriosis (DE) is the major clinical form of endometriosis, studies regarding the disease are typically based on ovarian (OE) and peritoneal (PE) lesions. DE pathogenesis is still a matter of great discussion because there are few studies exclusively involving DE lesions. The transcription factor encoded by the homeobox gene A10 (HOXA10) regulates the identity imparted to the undifferentiated paramesonephric duct during embryogenesis. The gene is expressed in the myometrium and endometrium during adult life in a well-defined spatial and temporal mode. It has been suggested that HOXA10 plays a role in endometriosis pathogenesis because it is expressed in OE, PE, pulmonary endometriosis, and rectovaginal endometriosis, which is a clinical form of DE. Thus, HOXA10 may be necessary for \"de novo\" endometrial development from undifferentiated tissues. Both estradiol and progesterone activate HOXA10 transcription and directly regulate its action. These hormones are involved in DE pathogenesis, and therefore their activities could be assessed by studying the tissue expression of their receptors. Rectosigmoid endometriosis (RE) is a representative model for studying DE. In this study, we evaluated the protein expression of HOXA10, the estrogen receptor (ER) isoforms alfa (ER-alfa) and beta (ER-beta), the progesterone receptor AB (PR), and the PR isoform B (PR-B) in lesions (LES) and adjacent smooth muscle (SM) of RE from infertile patients during the proliferative and secretory phases of the menstrual cycle. METHODS: LES and SM samples from RE patients were grouped in tissue microarray blocks. Each of the proteins was analyzed by immunohistochemistry using regular optical microscopy (OM) and a software-assisted analysis of digitalized images as well as morphometric analysis (MA). RESULTS: HOXA10 was expressed in the stroma of the LES during the secretory phase based on OM. ER-alfa and ER-beta were expressed in the glands and stroma of LES and SM during both phases based on OM and MA. PR and PR-B were expressed in the glands and stroma of LES during both phases; however, PR-B had higher expression during the secretory phase, independent of its expression in the LES or SM. HOXA10 expression was directly correlated with PR and PR-B expression in RE. In addition, there was no correlation between the expression of ER-alfa and ER-beta with HOXA10, PR, or PR-B during any phase of the menstrual cycle or site of expression. CONCLUSIONS: HOXA10 is expressed in RE outside of its spatial domain of expression, and may be necessary for \"de novo\" development of DE, including RE. Progesterone might stimulate HOXA10 expression and regulate this action, which is most likely mediated by PR-B. Moreover, estradiol exerts its mitogenic effect in RE though ER-alfa and ER-beta
Ortega-Verdugo, Paula. "Two-step selective caries removal of extensive lesions: treatment decision factors, success and cost-effectiveness". Diss., University of Iowa, 2019. https://ir.uiowa.edu/etd/7007.
Pełny tekst źródłaMoritz, Franco [Verfasser], Philippe [Akademischer Betreuer] Schmitt-Kopplin i Michael [Akademischer Betreuer] Rychlik. "Deep Metabotyping of exhaled breath condensate (EBC) – characterization of surrogate markers for systemic metabolism and non-invasive diagnostics in Diabetes / Franco Moritz. Gutachter: Philippe Schmitt-Kopplin ; Michael Rychlik. Betreuer: Philippe Schmitt-Kopplin". München : Universitätsbibliothek der TU München, 2014. http://d-nb.info/1070372439/34.
Pełny tekst źródłaAli, Shahnewaz. "Robotic vision for knee arthroscopy". Thesis, Queensland University of Technology, 2022. https://eprints.qut.edu.au/235890/1/Shahnewaz%2BAli%2BThesis%282%29.pdf.
Pełny tekst źródłaCunha, Rita Gamboa Pinto da. "Comparison of the diagnostic accuracy of Transvaginal Sonovaginography and Magnetic Resonance Imaging in patients with suspicion of Deep Infiltrating Endometriosis". Master's thesis, 2016. https://repositorio-aberto.up.pt/handle/10216/89390.
Pełny tekst źródłaCunha, Rita Gamboa Pinto da. "Comparison of the diagnostic accuracy of Transvaginal Sonovaginography and Magnetic Resonance Imaging in patients with suspicion of Deep Infiltrating Endometriosis". Dissertação, 2016. https://repositorio-aberto.up.pt/handle/10216/89390.
Pełny tekst źródłaViaña, JNM. "Ethical considerations for deep brain stimulation and other invasive neurotechnological trials in people with Alzheimer's disease". Thesis, 2019. https://eprints.utas.edu.au/31899/1/Viana_whole_thesis_ex_pub_mat.pdf.
Pełny tekst źródłaLin, Yan-Liang. "Semi-automatic classification of tree species using a combination of RGB drone imagery and mask RCNN: case study of the Highveld region in Eswatini". Master's thesis, 2021. http://hdl.handle.net/10362/113903.
Pełny tekst źródłaTree species identification forms an integral part of biodiversity monitoring. Locating at-risk species and predicting their distribution is equally as important as tracing invasive alien plant species distributions. The high prevalence of the latter and their destructive impact on the environment is the focus for this thesis. In areas of the world where technology limitations are restrictive, an approach using low-cost, available RGB drone imagery is proposed to train advanced deep learning models to distinguish individual tree species; three dominant species (Pinus elliotti, Eucalyptus grandis and Syzygium cordatum) providing the bulk of sampling data, of which the first two are highly invasive in the region. This study explored the efficacy of utilizing Mask RCNN, an instance segmentation deep neural network, in identifying multiple classes of trees within the same image. In line with the low-cost approach, Google Colaboratory was utilized which drastically lowers the training time necessary and alleviates the need for high GPU systems. The model was trained on imagery from three study areas which were representative of three distinct landscapes: very dense forest, moderately dense forest with overlapping canopies, and open forest. The results indicate decent performance in open forest landscapes where overlapping tree crowns is infrequent with mean Average Precision of 0.71. On the contrary, in a dense forest landscape with many interlocking tree crowns, a mean Average Precision of 0.43 is highly indicative of the model’s poor performance in such environments. The trained network was also observed to have higher confidence scores of detected objects within the open forest study areas as opposed to dense forest.
Schmitt, Cédric. "L'élastographie ultrasonore dynamique vasculaire : une nouvelle modalité d'imagerie non-invasive pour la caractérisation mécanique de la thrombose veineuse". Thèse, 2011. http://hdl.handle.net/1866/5464.
Pełny tekst źródłaThe venous thromboembolism such as the lower limb deep venous thrombosis (DVT) is a vascular pathology characterized by a blood clot formation that induces partial or total vessel lumen occlusion. Pulmonary embolism is a fatal complication of DVT where the clot detaches from the wall, circulates in the blood flow, and produces an obstruction of pulmonary arterial branches. The combination of clinical prediction rules (signs or symptoms) and blood tests (D-dimer testing) coupled to venous ultrasonography (i.e. compression ultrasonography, color Doppler) allows an accurate diagnosis of first DVT. Nevertheless, such clinical tools present poor results to detect recurrent thrombotic events. Then, in order to guide patients towards optimal therapy, the problem is no more to detect the presence of thrombus, but to evaluate its maturity and its age, which are correlated to their mechanical properties (e.g. elasticity, viscosity). The dynamic elastography (DE) has been recently proposed as a novel non-invasive imaging modality capable to characterize the quantitative mechanical properties of tissues. The DE is based on the analysis of acoustical parameters (i.e. velocity, attenuation, wave pattern) of low frequency (10-7000 Hz) shear waves propagating within the probed medium. Such shear waves generated by external vibration, or remotely using ultrasound beam focalisation (radiation force), were tracked using ultra-fast ultrasound or magnetic resonance imaging. A method based on DE and adapted to mechanical characterization of venous thrombosis may allow the quantification of diseases severity in order to improve the final diagnosis. This thesis presents the works related to the development and complete validation of a novel non-invasive elastography imaging method for the quantitative and reliable estimation of mechanical properties of venous thrombosis. In order to fulfil the main objective, it is first necessary to improve knowledge about mechanical behaviours of blood clot (coagulated blood) subjected to a dynamic solicitation similar to DE. The shear storage (elastic behaviour, G’) and loss (viscous behavior, G’’) moduli of porcine blood clots are measured by DE during the blood coagulation kinetics (at 70 Hz) and after completely coagulation (between 50 Hz and 160 Hz). These results are the first dynamic behaviour measurements of blood clots in such wide frequency range. The subsequent step consists in introducing an innovative reference instrument (« gold standard »), called RheoSpectris, dedicated to measure the hyper-frequency viscoelasticity (between 10 Hz and 1000 Hz) of materials and biomaterials. This tool is indispensable to validate new dynamic elastography techniques. A comparative study between RheoSpectris and classical rheometry is performed to validate the measurements on different materials (silicon, thermoplastic, biomaterials, gel). The excellent agreement between both technologies allows to conclude that RheoSpectris is a reliable instrument for mechanical measurements at high frequencies, which is not always possible with current tools. The theoretical basis of a novel elastographic imaging modality, labelled SWIRE (« shear wave induced resonance dynamic elastography ») is presented and validated on vascular phantoms. Such approach allows the characterization of mechanical properties of a confined inclusion (e.g. blood clot) from its resonance (displacement amplification) due to the propagation of judiciously oriented shear waves. SWIRE has also the advantage to amplify the vibration amplitude within the heterogeneity to help for its detection and segmentation. Finally, the method DVT-SWIRE ((« Deep venous thrombosis – SWIRE ») is adapted to the quantitative elasticity estimation of venous thrombosis in the context of clinical use. DVT-SWIRE exploits the first resonance frequency measured within the thrombosis during the plane (vibration of rigid plate) or cylindrical (simulating supersonic radiation force generation) shear waves propagation. The technique is applied on DVT phantoms and the results are compared to those given by the RheoSpectris reference instrument. This method is also used successfully in an ex vivo study for the elasticity assessment of explanted porcine thrombosis surgically induced in vivo.
Gonçalves, Carolina do Carmo Lages. "Identificação automática de plantas invasoras em imagens aéreas". Master's thesis, 2019. http://hdl.handle.net/10071/20313.
Pełny tekst źródłaInvasive species are known for their rapid dissemination, involving the loss of biodiversity in affected areas, becoming important to monitor the forest areas in order to control these species. This dissertation presents an architecture for the detection of the invasive species Acacia Longifolia in aerial images, particularly relevant in Portugal. The architecture includes capturing aerial images through unmanned aerial vehicles (UAVs), preprocessing the images and splitting the data into training, validation and testing sets. It also includes a trained convolutional neuronal network for automatic species classification based on the acquired aerial images. Two models were built, whose architecture differs in the last layer responsible for classifying samples with 100 x 100 pixels, obtained by a sliding window along the high-resolution images. One of the networks classifies according to nine classes (e.g., Acacia L., Vegetation, Roadway), and the obtained classification is then converted into a binary classification through the confusion matrix, having an accuracy of 98.5% for testing set. The second model was trained for binary classification for the presence of Acacia L., achieving an accuracy of 98.7% for the test set. The results show that the multi-classification does not hamper the performance of Acacia Longifolia detection and provides UAV with additional environmental information. Finally, an approach has been developed to improve the accuracy of the system by calling an expert to review the predictions produced by the system, balancing the expected benefit of accuracy improvement with the cost of calling the expert.