Gotowe bibliografie tematyczne / Complexes de zinc

Spis treści

  1. Artykuły w czasopismach
  2. Rozprawy doktorskie
  3. Książki
  4. Części książek
  5. Streszczenia konferencji
  6. Raporty organizacyjne

Gotowa bibliografia na temat „Complexes de zinc”

Autor: Grafiati
Data publikacji: 23 listopada 2024

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Artykuły w czasopismach na temat "Complexes de zinc"

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Nabeshima, Tatsuya, Yusuke Chiba, Takashi Nakamura i Ryota Matsuoka. "Synthesis and Functions of Oligomeric and Multidentate Dipyrrin Derivatives and their Complexes". Synlett 31, nr 17 (24.07.2020): 1663–80. http://dx.doi.org/10.1055/s-0040-1707155.

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The dipyrrin–metal complexes and especially the boron complex 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) have recently attracted considerable attention because of their interesting properties and possible applications. We have developed two unique and useful ways to extend versatility and usefulness of the dipyrrin complexes. The first one is the linear and macrocyclic oligomerization of the BODIPY units. These arrangements of the B–F moieties of the oligomerized BODIPY units provide sophisticated functions, such as unique recognition ability toward cationic guest, associated with changes in the photophysical properties by utilizing unprecedented interactions between the B–F and a cationic species. The second one is introduction of additional ligating moieties into the dipyrrin skeleton. The multidentate N2Ox dipyrrin ligands thus obtained form a variety of complexes with 13 and 14 group elements, which are difficult to synthesize using the original N2 dipyrrin derivatives. Interestingly, these unique complexes exhibit novel structures, properties, and functions such as guest recognition, stimuli-responsive structural conversion, switching of the optical properties, excellent stability of the neutral radicals, etc. We believe that these multifunctional dipyrrin complexes will advance the basic chemistry of the dipyrrin complexes and develop their applications in the materials and medicinal chemistry fields.1 Introduction2 Linear Oligomers of Boron–Dipyrrin Complexes3 Cyclic Oligomers of Boron–Dipyrrin Complexes4 A Cyclic Oligomer of Zinc–Dipyrrin Complexes5 Group 13 Element Complexes of N2Ox Dipyrrins6 Chiral N2 and N2Ox Dipyrrin Complexes7 Group 14 Element Complexes of N2O2 Dipyrrins8 Other N2O2 Dipyrrin Complexes with Unique Properties and Functions9 Conclusion
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Schäfer, Sebastian, Ralf Köppe, Michael T. Gamer i Peter W. Roesky. "Zinc–silylene complexes". Chemical Communications 50, nr 77 (15.08.2014): 11401. http://dx.doi.org/10.1039/c4cc04714a.

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Nieuwenhuizen, Peter J. "Zinc accelerator complexes." Applied Catalysis A: General 207, nr 1-2 (luty 2001): 55–68. http://dx.doi.org/10.1016/s0926-860x(00)00613-x.

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Midlej, Victor, Felipe Rubim, Wilmer Villarreal, Érica S. Martins-Duarte, Maribel Navarro, Wanderley de Souza i Marlene Benchimol. "Zinc-clotrimazole complexes are effective against Trichomonas vaginalis". Parasitology 146, nr 9 (3.05.2019): 1206–16. http://dx.doi.org/10.1017/s003118201900043x.

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AbstractTrichomonas vaginalis is a protozoan parasite that causes trichomoniasis in humans, the most prevalent non-viral sexually transmitted disease (STD). Imidazole compounds are used for the treatment of trichomoniasis, and metronidazole is the most commonly prescribed. However, these compounds can lead to parasite resistance and unwanted side effects. Therefore, there is a need for an alternative treatment for this disease. Here, we explored the potential of clotrimazole (CTZ) and zinc compounds, as well as CTZ complexed with zinc salts ([1] acetate [Zn(CTZ)2(Ac)2] and [2] a chloride [Zn(CTZ)2Cl2] complexes) against T. vaginalis. We synthesized the zinc complexed CTZ compounds and determined their concentration values that inhibited parasite growth by 50% (IC50). We used scanning and transmission electron microscopy to visualize the ultrastructural alterations induced by CTZ and their zinc complexes. The incubation of the parasites with [Zn(CTZ)2(Ac)2] complex inhibited their growth, yielding an IC50 of 4.9 µm. Moreover, there were changes in the shape of treated parasites, including the formation of surface projections that subsequently detached from the cell, in addition to changes in the hydrogenosomes, endoplasmic reticulum and Golgi complex. We found [Zn(CTZ)2(Ac)2] to be a highly effective compound against T. vaginalis in vitro, suggesting its potential utility as an alternative chemotherapy for trichomoniasis.
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Müller-Hartmann, A., i H. Vahrenkamp. "Binary zinc-oligophosphate complexes". Inorganica Chimica Acta 300-302 (kwiecień 2000): 531–36. http://dx.doi.org/10.1016/s0020-1693(99)00614-3.

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Meyer, Nils, i Peter W. Roesky. "Chiral Aminotroponiminate Zinc Complexes". Organometallics 28, nr 1 (12.01.2009): 306–11. http://dx.doi.org/10.1021/om800858t.

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Datta, Simmi, Michael T. Gamer i Peter W. Roesky. "TADDOLate complexes of zinc". Dalton Transactions, nr 13 (2008): 1761. http://dx.doi.org/10.1039/b715123c.

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Marks, Sebastian, Ralf Köppe, Tarun K Panda i Peter W Roesky. "Unprecedented Zinc-Borane Complexes". Chemistry - A European Journal 16, nr 24 (12.05.2010): 7096–100. http://dx.doi.org/10.1002/chem.201000571.

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Sudbrake, Claas, Bodo Müller i Heinrich Vahrenkamp. "Hexakis(alcohol)zinc Complexes". European Journal of Inorganic Chemistry 1999, nr 11 (listopad 1999): 2009–12. http://dx.doi.org/10.1002/(sici)1099-0682(199911)1999:11<2009::aid-ejic2009>3.0.co;2-n.

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Walz, Rainer, Michael Ruf i Heinrich Vahrenkamp. "(Pyrazolylborato)zinc−Aldehyde Complexes". European Journal of Inorganic Chemistry 2001, nr 1 (styczeń 2001): 139–43. http://dx.doi.org/10.1002/1099-0682(20011)2001:1<139::aid-ejic139>3.0.co;2-6.

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Rozprawy doktorskie na temat "Complexes de zinc"

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Doerrer, Linda H. (Linda Helen) 1968. "Cobalt, zinc, and cadminum tropocoronand complexes". Thesis, Massachusetts Institute of Technology, 1997. http://hdl.handle.net/1721.1/43296.

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Tirel, Emmanuel. "Zinc complexes for phosphate diester hydrolysis". Thesis, University of Sheffield, 2014. http://etheses.whiterose.ac.uk/7788/.

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This work focuses on catalysing the hydrolysis of DNA-like substrate with mononuclear zinc complexes. Particular attention is given to find new ways of activating the nucleophile of the reaction and to study the impact of organic groups that affect the microenvironment of the metal ion.
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Moreton, A. D. "Structure and reactivity of some aqueous zinc complexes". Thesis, University of Kent, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375179.

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Gianopoulos, Christopher G. "Development of Bulky Dipyrromethene Complexes of Aluminum, Zinc, and Rhodium". University of Toledo / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1418317025.

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Pratt, Jo-Anne Margaret. "The development of zinc (II) selective fluorescent ligands /". Title page, contents and abstract only, 1995. http://web4.library.adelaide.edu.au/theses/09PH/09php915.pdf.

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Elrod-Erickson, Monica (Monica Ann) 1969. "Structural and biochemical studies of zinc finger-DNA complexes". Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/49650.

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Ritch, Grayson D. "Synthesis, Characterization, and Reactivity of Novel Zinc Coordination Complexes". Kent State University Honors College / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ksuhonors1399675758.

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Dollberg, Christopher Lawrence. "Zinc and ruthenium quinone diimine complexes synthesis and photophysical properties /". Columbus, Ohio Ohio State University, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1071171484.

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Thesis (Ph. D.)--Ohio State University, 2003.
Title from first page of PDF file. Document formatted into pages; contains xvii, 171 p.; also includes graphics (some col.). Includes abstract and vita. Advisor: Claudia Turro, Dept.of Chemistry. Includes bibliographical references (p. 168-171).
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Tabone, Roberta. "Sinthesys of heteroleptic zinc complexes for imaging in living cells". Master's thesis, Alma Mater Studiorum - Università di Bologna, 2019. http://amslaurea.unibo.it/19188/.

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This thesis arose from an interest in luminescence heteroleptic bis(dipyrrinato) Zn (II) complexes and their application in cell imaging, due to their attractive and fascinating characteristics. Among imaging technologies, near-infrared fluorescence imaging has been dedicated immense attention owing to its low absorption and autofluorescence from surrounding organism and tissues in this specific spectral region, which minimize background interference and improve tissue depth penetration. An ideal near-infrared probe should be equipped with excellence chemical and photophysical properties. The target of this work is the synthesis of new heteroleptic bis(dipyrrinato) Zn (II) complexes having two main features: the emission in the near-infrared region and water-solubility. In order to purse these intentions, the low-energy emission was achieved by expansion of π-conjugation of simple dipyrrins using Knoevenagel condensation106 and tri(ethylene)glycol chain was introduced to increase the water solubility of the final complex. Photophysical and luminescent properties of the new complexes were investigated. Finally, with a view to a potential biological use of these new complexes in biological environments, their biocompatibility was tested using a cell viability assay: (3-(4,5-dimethylthiazol-2-yl)-2’-5’-diphenyltetrazolium bromide (MTT) assay.
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Yang, Wen Yu. "Luminescent zinc and lanthanide complexes based on 2,2 '-dipyridylamine derivatives". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0020/MQ52968.pdf.

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Książki na temat "Complexes de zinc"

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McMaster, Jonathan. Copper and Zinc complexes of bi-imidazole ligands. Manchester: University of Manchester, 1995.

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Coleman, A. P. Spectroscopic aspects of alkyl complexes of zinc, cadmium and mercury. Norwich: University of East Anglia, 1990.

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Bhalla, Rajiv. Copper and zinc complexes of Bis- and Tris-imidazole ligands. Manchester: University ofManchester, 1995.

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1941-, Rainsford K. D., red. Copper and zinc in inflammatory and degenerative diseases. Dordrecht: Kluwer Academic Publishers, 1998.

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Ferraz de Paiva, Raphael Enoque. Gold(I,III) Complexes Designed for Selective Targeting and Inhibition of Zinc Finger Proteins. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-030-00853-6.

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Shlian, Daniel. Synthesis, Structures, and Reactivity of Zinc, Cadmium, and Magnesium Complexes Supported by Nitrogen Donor and Carboxylate Ligands. [New York, N.Y.?]: [publisher not identified], 2022.

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Sattler, Wesley Ian. (I) Zinc complexes as synthetic analogues for carbonic anhydrase and as catalysts for H₂ production and CO₂ functionalization . . . [New York, N.Y.?]: [publisher not identified], 2012.

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Christenson, Scott C. Contamination of wells completed in the Roubidoux aquifer by abandoned zinc and lead mines, Ottawa County, Oklahoma. Oklahoma City, Okla: U.S. Dept. of the Interior, U.S. Geological Survey, 1995.

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Christenson, Scott C. Contamination of wells completed in the Roubidoux aquifer by abandoned zinc and lead mines, Ottawa County, Oklahoma: [microform]. Oklahoma City, Okla: U.S. Dept. of the Interior, U.S. Geological Survey, 1995.

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Christenson, Scott C. Contamination of wells completed in the Roubidoux aquifer by abandoned zinc and lead mines, Ottawa County, Oklahoma: [microform]. Oklahoma City, Okla: U.S. Dept. of the Interior, U.S. Geological Survey, 1995.

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Części książek na temat "Complexes de zinc"

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Meyer, B. K. "Bound Exciton Complexes". W Zinc Oxide, 169–99. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-10577-7_7.

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Sukumar, Ethirajan, Vajiravelu Sivamurugan i E. Rajkumar. "Unique Complexes of Zinc and Their Applications". W Zinc, 169–84. Boca Raton: CRC Press, 2024. http://dx.doi.org/10.1201/9781003412472-15.

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Kimura, Eiichi, Tohru Koike i Mitsuhiko Shionoya. "Advances in Zinc Enzyme Models by Small, Mononuclear Zinc (II) Complexes". W Metal Sites in Proteins and Models, 1–28. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/3-540-62874-6_7.

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Bochmann, Manfred, Gabriel Bwembya, Kevin J. Webb, M. A. Malik, J. R. Walsh i P. O'Brien. "Arene Chalcogenolato Complexes of Zinc and Cadmium". W Inorganic Syntheses, 19–24. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470132623.ch5.

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Claridge, R. F. C. "1.26 Zinc-centered radicals". W Inorganic Radicals, Metal Complexes and Nonconjugated Carbon Centered Radicals. Part 1, 109–11. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-48466-0_28.

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Howard, J. A. "2.16 Zinc-centered radicals". W Inorganic Radicals, Metal Complexes and Nonconjugated Carbon Centered Radicals. Part 1, 244–45. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-48466-0_67.

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Sorenson, J. R. J. "Copper complexes in the treatment of experimental inflammatory conditions: inflammation, ulcers and pain". W Copper and Zinc in Inflammation, 69–84. Dordrecht: Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-009-2619-6_6.

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Beveridge, S. J. "Copper therapy of inflammatory disorders: efficacy and biodistribution of topically applied copper complexes". W Copper and Zinc in Inflammation, 85–92. Dordrecht: Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-009-2619-6_7.

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Kimura, Eiichi. "Macrocyclic Polyamine Zinc(II) Complexes as Advanced Models for Zinc(II) Enzymes". W Progress in Inorganic Chemistry, 443–91. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470166420.ch6.

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Sorenson, J. R. J. "Copper complexes for therapy of cancer and autoimmune diseases". W Copper and Zinc in Inflammatory and Degenerative Diseases, 113–24. Dordrecht: Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-3963-2_7.

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Streszczenia konferencji na temat "Complexes de zinc"

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Aksenova, Iuliia, Alexander A. Prokopenko, Rimma T. Kuznetsova, Natalia A. Bumagina, Mikhail B. Berezin i Georgy V. Mayer. "Photonics of boron fluoride and zinc dipyrromethene complexes". W XIII International Conference on Atomic and Molecular Pulsed Lasers, redaktorzy Andrei M. Kabanov i Victor F. Tarasenko. SPIE, 2018. http://dx.doi.org/10.1117/12.2305471.

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Pale, Ville, Taru Nikkonen, Juho Helaja i Ilkka Tittonen. "Light-harvesting zinc chlorin-poly(4-vinylpyridine) complexes". W 2014 IEEE 14th International Conference on Nanotechnology (IEEE-NANO). IEEE, 2014. http://dx.doi.org/10.1109/nano.2014.6968052.

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Pirjol, Ticuta Negreanu. "POTENTIAL ANTIMICROBIAL AGENTS BASED ON CHLORHEXIDINE COMPLEXES WITH ZINC AND COPPER(II)". W 13th SGEM GeoConference on ECOLOGY, ECONOMICS, EDUCATION AND LEGISLATION. Stef92 Technology, 2013. http://dx.doi.org/10.5593/sgem2013/be5.v1/s20.101.

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Malavika, C. R., Anagha Maria Jose i Binu Varghese. "Syntheses and spectral characterization of zinc (II) complexes of N(4)-phenylsemicarbazones". W INTERNATIONAL CONFERENCE ON SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS: STAM 20. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0017124.

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Soldatovic, Tanja, i Enisa Selimovic. "Interaction of Zinc(II) and Copper(II) Terpyridine Complexes with Biomolecules". W 2nd International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2016. http://dx.doi.org/10.3390/ecmc-2-a001.

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Kumar, Amit, Ritu Srivastava, Arunandan Kumar, Modeeparampil N. Kamalasanan i Ishwar Singh. "Multi emissive layer type white organic light emitting diode based on zinc metal complexes". W 16th International Workshop on Physics of Semiconductor Devices, redaktorzy Monica Katiyar, B. Mazhari i Y. N. Mohapatra. SPIE, 2012. http://dx.doi.org/10.1117/12.924261.

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Soldatovic, Tanja, i Enisa Selimovic. "Interaction of Zinc(II) Complexes with Relevant Nitrogen Nucleophiles under Physiological Conditions". W 3rd International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2017. http://dx.doi.org/10.3390/ecmc-3-04638.

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Grokhlina, T. I., L. A. Panchenko, R. V. Polozov, V. S. Sivozhelezov i V. V. Ivanov. "Classification of DNA complexes of homeodomain and zinc-finger protein families: statistical analysis of DNA structures in interfaces of homeodomain-DNA complexes". W Mathematical Biology and Bioinformatics. Pushchino: IMPB RAS - Branch of KIAM RAS, 2018. http://dx.doi.org/10.17537/icmbb18.98.

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Han, Dongjia, Juan Du, Takayoshi Kobayashi, Tomohiro Miyatake, Hitoshi Tamiaki, Yanyan Li i Yuxin Leng. "Real-Time Vibrational Spectroscopy in Zinc Chlorin Aggregate as a Model of Supramolecular Antenna Complexes". W International Conference on Ultrafast Phenomena. Washington, D.C.: OSA, 2016. http://dx.doi.org/10.1364/up.2016.utu4a.14.

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Stevanović, Nevena Lj, Mia Stanković, Tina P. Andrejević, Darko P. Ašanin, Ivana M. Stanojević i Biljana Đ. Glišić. "DNA AND BSA INTERACTIONS OF COPPER(II) AND ZINC(II) COMPLEXES WITH ANTIFUNGAL AGENT FLUCONAZOLE". W 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.399s.

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Aromatic nitrogen-containing heterocycles (N-heterocycles) have attracted a considerable attention as scaffolds for compounds, which have an application in different pharmacological areas, ranging from vitamins to different antimicrobial and antitumor agents. In this respect, azoles are of special importance as potent and broad-spectrum agents used for the treatment of many invasive fungal infections. In the present study, the interaction of the clinically used antifungal drug fluconazole (fcz) and its copper(II) and zinc(II) complexes, {[CuCl2(fcz)2].5H2O}n (1) and {[ZnCl2(fcz)2]·2C2H5OH}n (2), with calf thymus DNA (ct- DNA) and bovine serum albumin (BSA) has been investigated. Fluorescence emission spectroscopy was applied for the binding study of complexes 1 and 2 and fcz with ct-DNA and BSA, while cyclic voltammetry was additionally used for investigation of their interactions with ct-DNA. The values of calculated binding constants (KA) of the investigated compounds towards ct-DNA and BSA follow the order fcz < 1 < 2 and 2 < fcz < 1, respectively.
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Raporty organizacyjne na temat "Complexes de zinc"

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Wagner, M. R. NMR investigation of dynamic processes in complexes of nickel(II) and zinc(II) with iminodiacetate, n-methyliminodiacetate and n-ethyliminodiacetate. Office of Scientific and Technical Information (OSTI), listopad 1985. http://dx.doi.org/10.2172/5982240.

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Xie, Weiwei. The role of zinc on the chemistry of complex intermetallic compounds. Office of Scientific and Technical Information (OSTI), styczeń 2014. http://dx.doi.org/10.2172/1226562.

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Dolan, Cheryl E. Structural and Functional Studies of the Protamine 2-Zinc Complex from Syrian Gold Hamster (Mesocricetus Auratus) Spermatids and Sperm. Office of Scientific and Technical Information (OSTI), sierpień 2004. http://dx.doi.org/10.2172/15014805.

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Genther-Schroeder, Olivia N., i Stephanie L. Hansen. Effect of Zinc Amino-Acid Complex and Optaflexx Feeding Duration on Growth Performance and Carcass Characteristics of Finishing Cattle. Ames (Iowa): Iowa State University, styczeń 2016. http://dx.doi.org/10.31274/ans_air-180814-562.

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Cross, L. E. Complete Thermodynamic Phenomenologies for Lead Zinc Niobate: Lead Titanate (PZN:PT) and the Lead Magnesium Niobate: Lead Titanate (PMT:PT) Single Crystal System. Fort Belvoir, VA: Defense Technical Information Center, czerwiec 2001. http://dx.doi.org/10.21236/ada390555.

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Jander, Georg, i Daniel Chamovitz. Investigation of growth regulation by maize benzoxazinoid breakdown products. United States Department of Agriculture, styczeń 2015. http://dx.doi.org/10.32747/2015.7600031.bard.

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Introduction Previous research had suggested that benzoxazinoids, a class of defensive metabolites found in maize, wheat, rye, and wild barley, are not only direct insect deterrents, but also influence other areas of plant metabolism. In particular, the benzoxazinoid 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxa- zin-3(4H)- one (DIMBOA) was implicated in: (i) altering plant growth by interfering with auxin signaling, and (ii) leading to the induction of gene expression changes and secondary plant defense responses. The overall goal of this proposal was to identify mechanisms by which benzoxazinoids influence other aspects of plant growth and defense. Specifically, the following hypotheses were proposed to be tested as part of an approved BARD proposal: Benzoxazinoid breakdown products directly interfere with auxin perception Global changes in maize and barley gene expression are induced by benzoxazinoid activation. There is natural variation in the maize photomorphogenic response to benzoxazinoids. Although the initial proposal included experiments with both maize and barley, there were some technical difficulties with the proposed transgenic barley experiments and most of the experimental results were generated with maize. Summary of major findings Previous research by other labs, involving both maize and other plant species, had suggested that DIMBOA alters plant growth by interfering with auxin signaling. However, experiments conducted in both the Chamovitz and the Jander labs using Arabidopsis and maize, respectively, were unable to confirm previously published reports of exogenously added DIMBOA effects on auxin signaling. Nevertheless, analysis of bx1 and bx2 maize mutant lines, which have almost no detectable benzoxazinoids, showed altered responses to blue light signaling. Transcriptomic analysis of maize mutant lines, variation in inbred lines, and responses to exogenously added DIMBOA showed alteration in the transcription of a blue light receptor, which is required for plant growth responses. This finding provides a novel mechanistic explanation of the trade-off between growth and defense that is often observed in plants. Experiments by the Jander lab and others had demonstrated that DIMBOA not only has direct toxicity against insect pests and microbial pathogens, but also induces the formation of callose in both maize and wheat. In the current project, non-targeted metabolomic assays of wildtype maize and mutants with defects in benzoxazinoid biosynthesis were used to identify unrelated metabolites that are regulated in a benzoxazinoid-dependent manner. Further investigation identified a subset of these DIMBOA-responsive compounds as catechol, as well as its glycosylated and acetylated derivatives. Analysis of co-expression data identified indole-3-glycerol phosphate synthase (IGPS) as a possible regulator of benzoxazinoid biosynthesis in maize. In the current project, enzymatic activity of three predicted maize IGPS genes was confirmed by heterologous expression. Transposon knockout mutations confirmed the function of the maize genes in benzoxazinoid biosynthesis. Sub-cellular localization studies showed that the three maize IGPS proteins are co-localized in the plastids, together with BX1 and BX2, two previously known enzymes of the benzoxazinoid biosynthesis pathway. Implications Benzoxazinoids are among the most abundant and effective defensive metabolites in maize, wheat, and rye. Although there is considerable with-in species variation in benzoxazinoid content, very little is known about the regulation of this variation and the specific effects on plant growth and defense. The results of this research provide further insight into the complex functions of maize benzoxazinoids, which are not only toxic to pests and pathogens, but also regulate plant growth and other defense responses. Knowledge gained through the current project will make it possible to engineer benzoxazinoid biosynthesis in a more targeted manner to produce pest-tolerant crops without negative effects on growth and yield.
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Contamination of wells completed in the Roubidoux aquifer by abandoned zinc and lead mines, Ottawa County, Oklahoma. US Geological Survey, 1995. http://dx.doi.org/10.3133/wri954150.

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