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Artykuły w czasopismach na temat "Cognitive ageing"

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Harada, Etsuko, Yuhki Harada, Tazu Mizunami, Shinnosuke Tanaka i Satoru Suto. "Cognitive Reflection Test and ageing: Relation with cognitive ageing". Proceedings of the Annual Convention of the Japanese Psychological Association 81 (20.09.2017): 2D—038–2D—038. http://dx.doi.org/10.4992/pacjpa.81.0_2d-038.

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Chuangchai, Warawoot, i Sebastiaan Raymaekers. "Design Perspective of Environmental Interventions through the Stroop Effect, Juggling, and Volunteering for Successful Ageing and Cognitive Health: A Review". Journal of Architectural/Planning Research and Studies (JARS) 20, nr 2 (28.11.2022): 71–84. http://dx.doi.org/10.56261/jars.v20.248825.

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Environmental design is one of the solutions that supports the idea of successful ageing as well as cognitive health. Designing with environmental interventions offers opportunities for restoration, maintenance, or even enhancement of cognition, particularly in ageing people. Problems of cognitive health, such as mild cognitive impairment and dementia, are frequently and naturally found in ageing people. Design practices and experimental studies in related fields are moving forward at a rapid pace. However, less data are available in relation to design perspectives for cognitive health in the ageing population. This article reviews the benefits of environmental interventions in enhancing cognitive function for ageing people. Relevant English language documents were searched and reviewed through online databases e.g. Scopus, PubMed, Web of Science, Google Scholar and ResearchGate. In this review, the environmental interventions include both physical and social environment interventions. The physical interventions focus on selective attention and decision-making via the Stroop effect and juggling balls respectively. The social intervention focuses on positive behaviour and benefits related to volunteerism and volunteer activities. This article presents environmental interventions that can be integrated as normal daily activities for ageing people to live healthier and more cognitively enriching lives. These interventions could be used in wellness design strategies and applications for designers. The findings of this review also extend the boundaries of designing for the ageing population as an advantage for specialists. Designing with an understanding of cognitive health in ageing people is beneficial and recommended.
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Rabbitt, Patrick, i Christine Lowe. "Patterns of cognitive ageing". Psychological Research 63, nr 3-4 (18.08.2000): 308–16. http://dx.doi.org/10.1007/s004269900009.

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Doyle, Colleen, Mary Luszcz i Peter Rendell. "Real and Perceived Effects of Ageing on Cognition". Australian Educational and Developmental Psychologist 9, nr 2 (listopad 1992): 18–23. http://dx.doi.org/10.1017/s081651220002664x.

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ABSTRACTA symposium on ageing research was held at the 7th Australian Developmental Conference in July 1992. The theme of the symposium was the effect of ageing on cognition. Empirical and theoretical papers presented evidence for cognitive decline in late adulthood. However, discussion of the modifiability of cognition tempered the pessimistic view of cognitive ability in old age. Interdisciplinary studies such as the Berlin Aging Study provide hope for the discovery of factors affecting successful ageing by examining the interaction between health, personality, social factors, and cognition.
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El YOUBI, Naoual, i Benaissa ZARHBOUCH. "COGNITIVE AGEING BETWEEN CUMULATIVE EFFECT OF LIFESTYLE AND CATCH-UP COGNITIVE INTERVENTIONS". International Journal of Humanities and Educational Research 5, nr 02 (1.04.2023): 1–13. http://dx.doi.org/10.47832/2757-5403.19.1.

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Normal neurocognitive aging is characterized by its selective effect on the damaged neuronal regions and at the cognitive level. This heterogeneous nature constituted a strong motive for deepening the research on the causes of the emergence of interindividual cognitive differences within the same age group, helped by functional brain imaging techniques. The study starts from this premise and aims to shed light on the concept of "successful aging" from a neurocognitive perspective. This concept is at the center of attention of many researchers in various disciplines as it is related to two basic concepts: The firs concept is "brain reserve." It is related to people’s lifestyle, and is built and accumulated over the course of life through people's behaviours that are neurologically, and cognitively (reserve indicators) stimulated. The second concept is "Overdue reserve”. It is related to intensive cognitive interventions (indicators of Overdue reserve), as a catch-up and efficient mechanism that enables people with low levels of brain reserve to stimulate neuroplasticity, which contributes to enhance their cognitive performance. This study aims to explore the appropriate conditions, and effective ways, to help people develop functional neurological resistance against the decline that characterizes human cognition with advancing age. Hence, maintaining proper cognitive functioning contributes to improving the quality of life of seniors as well as enabling them to age healthily: psychologically, cognitively, and socially.
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Meunier, Claire C., Ellen Smit, Annette L. Fitzpatrick i Michelle C. Odden. "Balance and cognitive decline in older adults in the cardiovascular health study". Age and Ageing 50, nr 4 (10.03.2021): 1342–48. http://dx.doi.org/10.1093/ageing/afab038.

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Abstract Background Previous studies have demonstrated an association between gait speed and cognitive function. However, the relationship between balance and cognition remains less well explored. This study examined the cross-sectional and longitudinal relationship of balance and cognitive decline in older adults. Methods A cohort of 4,811 adults, aged ≥65 years, participating in the Cardiovascular Health Study was followed for 6 years. Modified Mini-Mental State Examination (3MSE) and Digit Symbol Substitution Test (DSST) were used to measure cognition. Tandem balance measures were used to evaluate balance. Regression models were adjusted for demographics, behavioural and disease factors. Results Worse balance was independently associated with worse cognition in cross-sectional analysis. Longitudinally, participants aged ≥76 years with poorer balance had a faster rate of decline after adjustment for co-variates: −0.97 points faster decline in 3MSE per year (95% confidence interval (CI): −1.32, −0.63) compared to the participants with good balance. There was no association of balance and change in 3MSE among adults aged <76 years (P value for balance and age interaction < 0.0001). DSST scores reflected −0.21 (95% CI: −0.37, −0.05) points greater decline when adjusted for co-variates. In Cox proportional hazard models, participants with worse balance had a higher risk of being cognitively impaired over the 6 years of follow-up visits (adjusted HR:1.72, 95% CI: 1.30, 2.29). Conclusions Future studies should evaluate standing balance as a potential screening technique to identify individuals at risk of cognitive decline. Furthermore, a better understanding of the pathophysiological link between balance and cognition may inform strategies to prevent cognitive decline.
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Newton, Fleur. "The effect of Cognitive Stimulation Therapy (CST) groups for dementia on participant’s attitudes to ageing: A practice-based study". FPOP Bulletin: Psychology of Older People 1, nr 133 (styczeń 2016): 25–31. http://dx.doi.org/10.53841/bpsfpop.2016.1.133.25.

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This practice-based study investigated the effects of Cognitive Stimulation Therapy (CST) in everyday NHS clinical settings on both routine outcomes and attitudes to ageing. This is important given that negative ageist beliefs have been linked to decline in health and wellbeing among older people, especially those with a dementia diagnosis. A quantitative pre-test/post-test design was used to evaluate changes in participant outcomes for cognition, quality of life and ageing attitudes. A total of 82 CST participants with mild to moderate dementia were included in the study. Significant improvements on measures of quality of life and attitudes to ageing were found pre- to post-CST, and a holding pattern of no change was observed for cognition. A significant positive correlation was established between ageing attitudes and quality of life. Demographic characteristics were not found to have an influence on the treatment effects of CST. These findings provide additional evidence that CST can produce routine improvements in clinical practice settings that are equally applicable across age and gender. Of clinical significance is the finding that CST improves the attitudes to ageing of older people with dementia, as this is the first time it has been empirically studied. This further highlights the potential of CST as a de-stigmatising, positive ageing intervention.
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Taylor, Morag, Stephen Lord, Annika Toots i Close Jacqueline. "33 Cognitive Domain Associations with Balance Performance in Community – Dwelling Older People with Cognitive Impairment". Age and Ageing 48, Supplement_4 (grudzień 2019): iv9—iv12. http://dx.doi.org/10.1093/ageing/afz164.33.

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Abstract Aims Investigate the relationship between global cognition and cognitive domain function and balance performance in a large sample of older people with cognitive impairment. Methods Three hundred and nine community-dwelling older people (mean age=82 years; 47% female) with cognitive impairment were recruited for the iFOCIS fall prevention randomised controlled trial. Baseline assessments completed before randomisation were used for analyses and included the Addenbrooke’s Cognitive Examination-III (ACE-III; global cognitive function) and its individual cognitive domains (attention; memory; verbal fluency; language; visuospatial ability) and executive function, further examined using the Frontal Assessment Battery (FAB). Balance performance was derived by averaging postural sway on floor and foam, maximal balance range (reverse z-score) and co-ordinated stability z-scores. With balance performance as the dependent variable, global cognition and each cognitive domain were entered into multivariate linear regression models. Results Mean (± standard deviation) ACE-III and FAB scores were 62.8±19.2 and 11.4±4.6 respectively. In linear regression analyses adjusted for covariates, global cognitive function and each cognitive domain were significantly associated with balance performance. Executive function (verbal fluency; β=-.248, p<0.001, adjusted R2=0.376) and visuospatial ability (β=-.250, p<0.001, adjusted R2=0.381) had the strongest and memory the weakest (β=-.119, p=0.018, adjusted R2=0.334) association with balance. Visuospatial ability remained significantly associated with balance performance when adjusted for attention, memory, language, verbal fluency and the FAB. Executive function (verbal fluency) remained significantly associated with balance when adjusted for attention, memory, language and visuospatial ability. Conversely, attention, memory, and language did not withstand adjustment for visuospatial ability or executive function. Conclusions Poorer global cognition and performance in each cognitive domain were associated with poorer balance performance in this large sample of community-dwelling older people with cognitive impairment. Visuospatial ability and executive function were independently associated with balance, highlighting the role higher-level cognitive processes and spatial perception and processing play in postural control.
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Taylor, Morag, Annika Toots, Jacqueline C. T. Close, Kim Van Schooten, Matthew Brodie i Kim Delbaere. "162 Walking, Thinking and Daily-Life Activity in Older People with Dementia". Age and Ageing 48, Supplement_4 (grudzień 2019): iv34—iv39. http://dx.doi.org/10.1093/ageing/afz164.162.

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Abstract Gait has been linked with cognition in cognitively healthy and impaired older people. However, the studies in cognitively impaired people have been small, have not contrasted the strength of cognitive domain associations and have reported inconsistent findings. We examined baseline data of 309 older people with mild-moderate cognitive impairment (age 82±6 years; 47% female) who were participating in a large fall prevention randomised controlled trial. Gait speed was measured at usual pace over 2.4m and cognitive performance was assessed with the Addenbrooke’s Cognitive Examination-III (ACE-III). The ACE-III assesses cognitive domain performance (attention; memory; verbal fluency; language; visuospatial ability). Executive function (EF) was additionally examined using the Frontal Assessment Battery (FAB). Each cognitive domain was associated with gait speed in separate models adjusted for confounders. EF (verbal fluency and the FAB) demonstrated the strongest association which withstood adjustment for attention, memory, language and visuospatial ability. In contrast, visuospatial ability was the only cognitive domain to withstand adjustment for EF (verbal fluency, not the FAB). These findings support higher-order gait regulation. Characterising individuals at risk of negative health outcomes can assist in identifying effective prevention strategies. Forty-five older people with mild-moderate dementia were age-sex matched to two (n=90) healthy controls and all participants (age 81±6 years, 42% female) wore triaxial accelerometers (MoveMonitor, McRoberts) on their lower back for 7-days. Daily-life gait quantity and quality were estimated from the MoveMonitor. Steady-state clinical walking speed was assessed at usual pace over 2.4 to 10.0m. Participants with dementia had reduced gait quantity, slower clinical, habitual daily-life and maximum daily-life walking speeds and multi-domain gait impairment compared to controls. In participants with dementia, clinical walking speed more closely represented habitual daily-life walking speed, whereas in controls, it more closely represented maximum daily-life walking speed. These findings have assessment, functional (e.g. crossing roads) and training/treatment implications.
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McCall, Vikki, Alasdair C. Rutherford, Alison Bowes, Sadhana Jagannath, Mary Njoki, Martin Quirke, Catherine M. Pemble i in. "Othering Older People’s Housing: Gaming Ageing to Support Future-Planning". International Journal of Environmental Research and Public Health 21, nr 3 (5.03.2024): 304. http://dx.doi.org/10.3390/ijerph21030304.

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The ‘othering’ of ageing is linked to an integrated process of ageism and hinders planning for the future for both individuals and practitioners delivering housing and health services. This paper aims to explore how creative interventions can help personalise, exchange knowledge and lead to system changes that tackle the ‘othering’ of ageing. The Designing Homes for Healthy Cognitive Ageing (DesHCA) project offers new and creative insights through an innovative methodology utilising ‘serious games’ with a co-produced tool called ‘Our House’ that provides insights into how to deliver housing for older people for ageing well in place. In a series of playtests with over 128 people throughout the UK, the findings show that serious games allow interaction, integration and understanding of how ageing affects people professionally and personally. The empirical evidence highlights that the game mechanisms allowed for a more in-depth and nuanced consideration of ageing in a safe and creative environment. These interactions and discussions enable individuals to personalise and project insights to combat the ‘othering’ of ageing. However, the solutions are restrained as overcoming the consequences of ageism is a societal challenge with multilayered solutions. The paper concludes that serious gaming encourages people to think differently about the concept of healthy ageing—both physically and cognitively—with the consideration of scalable and creative solutions to prepare for ageing in place.
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Rozprawy doktorskie na temat "Cognitive ageing"

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Schweitzer, Pierre. "Cognitive ageing in everyday life". Thesis, Paris Sciences et Lettres (ComUE), 2017. http://www.theses.fr/2017PSLEP061/document.

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Les objectifs de cette thèse sont multiples: 1. concevoir un nouvel outil d'échantillonnage des expériences utilisant les technologies mobiles, qui soit durable et évolutif, et qui permette d'implémenter des tests cognitifs mobiles; 2. utiliser cet outil pour obtenir des informations écologiques sur les comportements et les performances cognitives; 3. valider la méthode; 4. analyser les interactions entre comportement et performance afin d'identifier les comportements sains ou à risque
This thesis has several objectives: 1. design a new experience sampling tool that is durable and evolutive, and allows to implement mobile cognitive tests; 2. use this tool to obtain ecological information on behaviors and cognitive performance; 3. validate the method; 4. analyze the relationships between behavior and performance to identify which behaviors are healthy or risky
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Majdi, Maryam. "Brain ageing : cognitive status and cortical synapses". Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=115704.

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This thesis focused on the spatiotemporal patterning of classical excitatory and inhibitory synaptic contacts accounting for the majority of cerebral cortical connections, in relation to ageing and cognitive status. These investigations tested the hypothesis that higher CNS functions depend on the balance between excitatory and inhibitory synaptic connections. Glutamatergic and GABAergic presynaptic bouton densities were determined in aged animals segregated according to their cognitive status into aged and cognitively unimpaired (AU) and aged and cognitively impaired (AI), using the Morris water maze. These two groups were compared in terms of behaviour and the pattern of excitatory and inhibitory synapses. It was evident that an excitatory and inhibitory presynaptic decline is associated with age-related cognitive impairments; whereby both glutamatergic and GABAergic boutons gradually diminish from young to AU to AI. Nevertheless, the balance between excitatory and inhibitory presynaptic inputs was maintained. To determine whether postsynaptic sites differed with respect to ageing and cognitive impairments, excitatory and inhibitory postsynaptic scaffold proteins were investigated in the same cohort of segregated aged animals. There was an imbalance in density ratio between immunoreactive sites of excitatory versus inhibitory postsynaptic scaffold proteins in AI animals. This resulted from a marked decrease in the density of excitatory postsynaptic sites. To further investigate ultrastructural aspects of excitatory synapses I carried out electron microscopical studies of cerebral cortex to measure the abundance of NR2 receptor subunits of the NMDA receptor- a receptor site directly associated with excitatory postsynaptic scaffold proteins. This study revealed that NR2 immunoreactive sites were largely preserved during age-related cognitive decline with an uneven profile distribution. Finally, protein expression of specific receptor subunits and key proteins representative of excitatory and inhibitory postsynaptic sites was investigated by semi-quantitative Western blot analyses in selected cortical areas. It was clear that many of these postsynaptic proteins are affected by age and cognitive status. The most striking change was a marked up-regulation in neuroligin-1 in AI animals, which may affect the delicate balance between excitatory versus inhibitory synaptic inputs. Another notable finding was the down-regulated expression of GluR2 receptor subunits in AI animals, which should have implications for neuronal Ca2+ regulation. In conclusion, we have demonstrated the greater vulnerability of excitatory postsynaptic sites in aged and cognitively impaired animals.
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Spokes, Tara. "Ageing and Cognitive Inhibition: An ERP analysis". Thesis, Griffith University, 2016. http://hdl.handle.net/10072/365459.

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Impaired cognitive inhibition is one of a number of changes in cognitive functioning that are associated with healthy ageing. Cognitive inhibition is the ability to suppress or withhold some cognitive process and includes the ability to block out distracting information. Successful cognitive inhibition underlies improved performance on a range of executive functions including problem solving, long-term planning and goal-directed behaviour (Darowski, Helder, Zacks, Hasher, & Hambrick, 2008). One theory posits that age-related deficits in cognitive inhibition may underlie general cognitive decline associated with older adults (Hasher & Zacks, 1988; Hasher, Zacks, & Rahhal, 1999). Previous behavioural studies have found that automatic, or unintentional cognitive inhibition is preserved with age while controlled, intentional cognitive inhibition is impaired in older adults (Collette, Germain, Hogge, & Van der Linden, 2009). In contrast, a number of neuroimaging studies suggest that older adults show less differentiation than young adults in neural processing of automatic and controlled tasks. In particular, it has been suggested that automatic tasks are processed more like controlled tasks, suggesting increased cognitive effort required to complete them (Germain & Collette, 2008).
Thesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Applied Psychology
Griffith Health
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Norris, Jade Eloise. "Numerical cognition in ageing : investigating the impact of cognitive ageing on foundational non-symbolic and symbolic numerical abilities". Thesis, University of Hull, 2015. http://hydra.hull.ac.uk/resources/hull:13762.

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Healthy ageing is associated with a gradual decline in several cognitive functions, including processing speed, inhibitory control, memory, executive functions, and problem solving. However, the trajectory of ability in numerical cognition in older age remains unclear. Some research investigating exact skills such as arithmetical problem solving have found declined numerical abilities in older age due to reduced access to effective strategies. However, other research has indicated stable or even enhanced mathematical and arithmetical abilities in older age. Furthermore, limited research is available on the impact of ageing on foundational numerical abilities. The effect of cognitive ageing on such foundational abilities poses an interesting question due to the innate, evolutionary nature of foundational numerical skills. It is possible that such automatic, innate and primitive abilities may be spared in ageing, alongside emotional processing, autobiographical memory, and vocabulary and verbal skills. Available studies investigating basic numerical abilities in ageing present contradictory results and methodological variation. Furthermore, although a limited number of studies have investigated foundational non-symbolic abilities in ageing, the effect of older age on foundational symbolic abilities is yet to be directly tested. The thesis therefore explicitly investigated the impact of healthy ageing on foundational non-symbolic and symbolic numerical processing with a series of experiments. Chapter 2 presents the first study to use classic numerosity discrimination paradigms to compare the non-symbolic and symbolic foundational numerical skills of a group of younger and older adults. Chapter 3 served to further investigate enhanced symbolic numerical abilities in older age found in chapter 2 using a number priming paradigm. The impact of life experience using numbers on foundational numerical skills in older age was studied in chapter 4, whereby older adults with a degree in mathematics were compared with those without explicit further mathematical education. The final two experimental chapters of the thesis examine the reliable measurement of the Approximate Number System in ageing, considering the impact of inhibitory control and mathematical achievement on acuity. Chapter 5 compares non-symbolic acuity in younger and older adults when using either spatially separated or intermixed non-symbolic dot displays. Finally, chapter 6 directly studies the impact of perceptual variables on ANS acuity in ageing, specifically focusing on total cumulative area, dot size, and convex hull (perimeter) congruency. The series of experiments presented in the thesis indicate that foundational numerical abilities are preserved in healthy ageing. Specifically, non-symbolic numerical abilities remain stable in older age, whereas foundational symbolic abilities are enhanced, possibly due to lifetime exposure to and experience with symbolic numbers. Furthermore, the thesis demonstrates the importance of task design in measuring non-symbolic numerical abilities in ageing, identifying methodological aspects which may lead to poorer acuity in older adults as a result of decline in other cognitive functions (e.g. inhibitory control). The thesis therefore contributes to the literature regarding numerical cognition in ageing, with foundational numerical abilities found to be preserved in healthy ageing. Preservation of such abilities in healthy ageing poses implications for pathological ageing, in that declined foundational numerical skills may serve to indicate pathological processes.
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Cook, Joanna Clare. "Ageing and inhibition in memory". Thesis, University of Southampton, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288442.

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Dijkstra, Jeanette Bernadette. "An operation under general anaesthesia and cognitive ageing". Maastricht : Maastricht : Neuropsych Publishers ; University Library, Maastricht University [Host], 1997. http://arno.unimaas.nl/show.cgi?fid=5798.

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Brailean, Anamaria. "Cognitive ageing and late-life depression across cultures". Thesis, King's College London (University of London), 2017. https://kclpure.kcl.ac.uk/portal/en/theses/cognitive-ageing-and-latelife-depression-across-cultures(7cdddef5-ebe0-42ce-a264-3eedff0354be).html.

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This thesis examined the role of education and depression symptoms to late-life cognitive inequalities. The inquiry was conducted in several stages. The first line of investigation examined whether a more highly educated recently born cohort had higher levels of cognitive performance and slower rates of cognitive decline in late life compared to a less highly educated earlier born cohort of the same age (65 to 75 years old at baseline). Data were used from the Longitudinal Ageing Study Amsterdam (LASA). Findings from Linear Mixed Models suggest that the later born cohort had higher baseline levels of processing speed, inductive reasoning and general cognitive performance, but showed similar or steeper rates of cognitive decline compared to the earlier born cohort. Education duration accounted for cohort differences in baseline levels of inductive reasoning and general cognitive performance, but it did not account for cohort differences in cognitive decline over 6 years of follow-up. The second line of research examined which symptom dimensions of depression may show stronger associations with cognitive dysfunctions in late life. This research question was addressed in two separate psychometric studies, one conducted among older adults in Latin American countries (10/66 study) and the other conducted among older adults in the Netherlands (LASA study). Multiple Indicators Multiple Causes Models were used to examine cross-sectional associations between cognitive abilities and latent depression dimensions in the context of adjustment for differences in item response behaviour due to country of residence, age, gender and cognitive function levels. Findings from the 10/66 study suggest that poorer delayed recall performance was related to higher affective suffering symptoms and higher motivational symptoms. Motivational symptoms had a stronger negative association with verbal fluency performance than affective suffering symptoms. In both studies item response biases were of small magnitude and did not affect substantive conclusions. The third line of investigation informs on the longitudinal direction of influence and timing of the association between cognitive abilities and depression symptoms (conceptualized as a unitary construct and as specific symptom dimensions). This inquiry was conducted in two separate studies: the 10/66 study with a follow-up duration of 3 years (using cross-lagged path analyses), and the LASA study with a follow-up duration of 13 years (using cross-domain latent growth curve models). Findings from the 10/66 study suggest that most prospective associations between cognitive abilities (i.e., verbal fluency, immediate recall and delayed recall) and overall depression symptoms/specific symptom-dimensions were bidirectional. Baseline motivational symptoms of depression were not related to follow-up verbal fluency performance, whereas baseline delayed recall performance was not related to follow-up affective suffering levels. Findings from the LASA study suggest that poor initial memory performance predicted an increase in overall depression symptoms and a specific increase in depressed affect over time, whereas processing speed decline was accompanied by an increase in overall depression symptoms and a specific increase in somatic symptoms. In conclusion, findings from this thesis suggest that education alone has a limited role in accounting for cohort differences in cognitive ageing. The interplay between depression and cognitive functioning is complex. Whether depression co-occurs, precedes, accompanies, or follows cognitive dysfunctions may depend on the depression symptom dimensions experienced and on the timing of the assessments.
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Penke, Lars. "Neuroscientific approaches to general intelligence and cognitive ageing". Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät II, 2011. http://dx.doi.org/10.18452/13979.

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Nach einem ausführlichem Überblick über den Kenntnisstand der Genetik und Neurowissenschaft von allgemeiner Intelligenz und einer methodischen Anmerkung zur Notwendigkeit der Berücksichtigung latenter Variablen in den kognitiven Neurowissenschaften am Beispiel einer Reanalyse publizierter Ergebnisse wir das am besten etablierte Gehirnkorrelat der Intelligenz, die Gehirngröße, aus evolutionsgenetischer Perspektive neu betrachtet. Schätzungen des Koeffizienten additiv-genetischer deuten an, dass es keine rezente direktionale Selektion auf Gehirngröße gegeben hat, was ihre Validität als Proxy für Intelligenz in evolutionären Studien in Frage stellt. Stattdessen deuten Korrelationen der Gesichtssymmetrie älterer Männer mit Intelligenz und Informationsverarbeitungsgeschwindigkeit an, dass organismusweite Entwicklungsstabilität eine wichtige Grundlage von unterschieden in kognitiven Fähigkeiten sein könnte. Im zweiten Teil dieser Arbeit geht es vornehmlich um die Alterung kognitiver Fähigkeiten, beginnend mit einem allgemeinen Überblick. Daten einer Stichprobe von über 130 Individuen zeigen dann, dass die Integrität verschiedener Nervenbahnen im Gehirn hoch korreliert, was die Extraktion eines Generalfaktors der Traktintegrität erlaubt, der mit Informationsverarbeitungsgeschwindigkeit korreliert. Der einzige Trakt mit schwacher Ladung auf diesem Generalfaktor ist das Splenium des Corpus Callosum, welches mit Veränderungen der Intelligenz über 6 Jahrzehnte korreliert und den Effekt des Bet2 adrenergischem Rezeptorgens (ADRB2) auf diese Veränderung mediiert, möglicherweise durch Effekte auf neuronale Komopensationsprozesse. Schließlich wird auf Basis neuer Analyseverfahren für Magnetresonanzdaten gezeigt, dass vermehrte Eiseneinlagerungen im Gehirn, vermutlich Marker für zerebrale Mikroblutungen, sowohl mit lebenslang stabilen Intelligenzunterschieden als auch mit der altersbedingten Veränderung kognitiver Fähigkeiten assoziiert sind.
After an extensive review of what is known about the genetics and neuroscience of general intelligence and a methodological note emphasising the necessity to consider latent variables in cognitive neuroscience studies, exemplified by a re-analysis of published results, the most well-established brain correlate of intelligence, brain size, is revisited from an evolutionary genetic perspective. Estimates of the coefficient of additive genetic variation in brain size suggest that there was no recent directional selection on brain size, questioning its validity as a proxy for intelligence in evolutionary analyses. Instead, correlations of facial fluctuating asymmetry with intelligence and information processing speed in old men suggest that organism-wide developmental stability might be an important cause of individual differences in cognitive ability. The second half of the thesis focuses on cognitive ageing, beginning with a general review. In a sample of over 130 subjects it has then been found that the integrity of different white matter tracts in the brain is highly correlated, allowing for the extraction of a general factor of white matter tract integrity, which is correlated with information processing speed. The only tract not loading highly on this general factor is the splenium of the corpus callosum, which is correlated with changes in intelligence over 6 decades and mediates the effect of the beta2 adrenergic receptor gene (ADRB2) on cognitive ageing, possibly due to its involvement in neuronal compensation processes. Finally, using a novel analytic method for magnetic resonance data, it is shown that more iron depositions in the brain, presumably markers of a history of cerebral microbleeds, are associated with both lifelong-stable intelligence differences and age-related decline in cognitive functioning.
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Marioni, Riccardo Emilio. "Inflammation and cognition : the association between biomarker levels, their genetic determinants, and age-related cognitive decline". Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/4436.

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Chronic in ammation and variations in blood flow have been implicated in the pathogenesis of cardiovascular disease. It is also possible that inflammatory and rheological processes are involved in the development of mild cognitive impairment and dementia, either through their association with vascular disease or via some other, more direct effect on the brain. Evidence is increasing for a causal relationship between Alzheimer's disease and inflammation, possibly related to inflammatory activation of microglia. Inflammatory processes may also be involved in the pathogenesis of cerebral small vessel disease, which in turn has been linked to cognitive impairment and dementia. There is also evidence showing that rheological factors affect cerebral blood flow. However, despite these findings, the associations between inflammatory and rheological markers and cognitive ability have not been extensively studied in large groups of ageing people. The primary aim of this thesis was to test for associations between late-life levels of inflammatory and rheological markers (C-reactive protein (CRP), fibrinogen, tumor necrosis factor (TNF)-α, interleukin (IL)-6, plasma viscosity, and haematocrit) and cognitive ability. A genetic analysis was then performed to model single nucleotide polymorphisms (SNPs) in the genes encoding the markers against cognition in an attempt to determine the weight of evidence for a causal inflammation-cognition association. Four studies were used to test these aims with the majority of the analysis being performed on the Aspirin for Asymptomatic Atherosclerosis (AAA) Trial (n = 3,350), and the Edinburgh Type 2 Diabetes Study (ET2DS) (n = 1,066). The Edinburgh Artery Study (n = 534), and the 1936 Lothian Birth Cohort (n = 1,091), were used as replication cohorts for the genetic analysis. All cohorts comprised community-dwelling, elderly citizens (aged around 70 years) living in central Scotland. With the exception of the ET2DS, all data used were for secondary analyses. Cognitive ability was assessed in all studies using comprehensive batteries of neuropsychological tests that included a measure of crystallised intelligence in the form of a vocabulary test. As performance on such tests varies little across a lifespan, adjusting for these scores in the late-life models enabled the determination of estimated lifetime cognitive change. In the case of the 1936 Lothian Birth Cohort an actual age-11 IQ measure was available in addition to the cognitive follow-up scores recorded at age-70. Linear regression showed small but significant associations between CRP, fibrinogen, and plasma viscosity, and cognition and estimated lifetime cognitive decline in the AAA Trial. Similar results were observed in the ET2DS for CRP, IL-6, and TNF-α. These associations tended to be of a magnitude whereby the markers explained 1% of the variance of the cognitive test scores. The cognitive domains most consistently associated with the markers were processing speed, and a data derived general intelligence factor. A novel genetic analysis was then undertaken to model SNPs against cognitive ability and decline. Most of the results generated were null findings. However, strongly significant associations were found between the rs2227412 fibrinogen beta gene SNP and the cognitive test scores in the ET2DS. Furthermore, the genotype associated with the lowest cognitive scores was also related to higher levels of plasma fibrinogen. Whilst replication of the association between the fibrinogen SNPs and cognition was not found across all cohorts, these results still indicate a potentially causal role for this haemostatic/inflammatory marker. To date, the majority of inflammation-cognition associations have focussed on the acute-phase protein CRP. The main outcomes from this thesis suggest that its close correlate, fibrinogen, is an equally, if not more important factor in the complex process of cognitive ageing.
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Rose, Rachel Anne. "The performance of older eyewitnesses on photographic identification lineups". Thesis, University of Portsmouth, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247494.

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Książki na temat "Cognitive ageing"

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Moody, Harry R. Economic Foundations for Creative Ageing Policy: Volume I Context and Considerations. New York: Palgrave Macmillan, 2015.

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Adler, Richard. Economic Foundations for Creative Ageing Policy, Volume II: Putting Theory into Practice. New York: Palgrave Macmillan, 2017.

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1960-, Sun Ron, red. Cognition and multi-agent interaction: From cognitive modeling to social simulation. Cambridge: Cambridge University Press, 2006.

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Hajduk, Mikuláš, Marek Sukop i Matthias Haun. Cognitive Multi-agent Systems. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-93687-1.

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Niazi, Muaz A., i Amir Hussain. Cognitive Agent-based Computing-I. Dordrecht: Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-3852-2.

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Far capitare le cose: Pensiero e azione nelle neuroscienze cognitive. Bologna: Il mulino, 2012.

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Dautenhahn, Kerstin, red. Human Cognition and Social Agent Technology. Amsterdam: John Benjamins Publishing Company, 2000. http://dx.doi.org/10.1075/aicr.19.

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Marie, Viccari Rosa, Verdin Regina i Jaques Patricia Augustin, red. Agent-based tutoring systems by cognitive and affective modeling. Hershey PA: Information Science Reference, 2008.

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Patrick, Rabbitt, red. Psychology of ageing: Critical concepts in psychology. Sussex, UK: Psychology Press, 2009.

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Grivois, Henri. Subjectivité et conscience d'agir: Approches cognitive et clinique de la psychose. Paris: Presses universitaires de France, 1998.

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Części książek na temat "Cognitive ageing"

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Christopher, Gary. "Basic Cognitive Processes". W The Psychology of Ageing, 44–57. London: Macmillan Education UK, 2014. http://dx.doi.org/10.1007/978-1-137-36844-7_3.

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Christopher, Gary. "Assessment of Cognitive Function". W The Psychology of Ageing, 110–24. London: Macmillan Education UK, 2014. http://dx.doi.org/10.1007/978-1-137-36844-7_8.

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Andrade, José Paulo. "Retarding brain ageing and cognitive decline". W Anti-ageing nutrients, 315–32. Chichester, UK: John Wiley & Sons, Ltd, 2015. http://dx.doi.org/10.1002/9781118823408.ch10.

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Melnattur, Krishna. "Sleep, Ageing, and Cognitive Decline". W Healthy Ageing and Longevity, 175–92. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-22468-3_9.

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Hogervorst, Eef, i Nils Niederstrasser. "Cognitive function, ageing, and dementia". W The Routledge International Handbook of Psychobiology, 539–66. Milton Park, Abingdon, Oxon ; New York, NY : Routledge, 2018.: Routledge, 2018. http://dx.doi.org/10.4324/9781315642765-36.

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Charness, Neil. "Technologies to Mitigate Cognitive Ageing". W The Routledge Handbook of the Economics of Ageing, 84–101. London: Routledge, 2023. http://dx.doi.org/10.4324/9781003150398-6.

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Krishnamoorthy, Kalaiselvi, Ponnulakshmi Rajagopal i Selvaraj Jayaraman. "Gut-Brain Interplay and Cognitive Degeneration". W Gut Microbiome and Brain Ageing, 71–92. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-8803-7_4.

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Zanto, Theodore P., i Adam Gazzaley. "Cognitive Control and the Ageing Brain". W The Wiley Handbook of Cognitive Control, 476–90. Chichester, UK: John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781118920497.ch27.

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Ihle, Andreas, Élvio R. Gouveia, Bruna R. Gouveia, Dan Orsholits i Matthias Kliegel. "Ageing and Reserves". W Withstanding Vulnerability throughout Adult Life, 239–52. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-4567-0_15.

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AbstractIn this chapter we elaborate on our conceptual view on vulnerability being the result of insufficient reserve build-up across the life course in various domains (e.g., cognitive reserve and relational reserve). Specifically, we propose that certain individuals are more vulnerable (than other, less vulnerable individuals) to impairments in human functioning because of insufficient reserves accumulated over their life course, which consequently exposes those individuals to greater difficulty to deal with threatening situations in old age in order to offset or prevent negative outcomes. To illustrate our novel perspective with empirical examples, we focus on cognitive and relational reserve domains and their role for cognitive health and well-being as aging outcomes. First, we elaborate on the build-up of these reserve domains across the life course, with a special focus on inter-individual differences in the pathways of reserve accumulation. Second, we concentrate on the role of reserves for human functioning in different groups of vulnerable individuals in old age. Third, we elaborate on the interplay of different reserve domains and their potential joint effects on aging outcomes. Finally, we conclude with an outlook for future research.
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Leipold, Bernhard. "Cognitive-motivational processes of intentional self-development". W Intentional Self-Development and Positive Ageing, 79–104. Abingdon, Oxon ; New York, NY : Routledge, 2020.: Routledge, 2019. http://dx.doi.org/10.4324/9781351261807-4.

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Streszczenia konferencji na temat "Cognitive ageing"

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Reddy, Gudur Raghavendra, Alethea Blackler, Doug Mahar i Vesna Popovic. "The effects of cognitive ageing on use of complex interfaces". W the 22nd Conference of the Computer-Human Interaction Special Interest Group of Australia. New York, New York, USA: ACM Press, 2010. http://dx.doi.org/10.1145/1952222.1952259.

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Agocs, Adam, Charlotte Besser i Marcella Frauscher. "Closer-to-reality artificial ageing of engine oils with implemented nitration". W 2022 IEEE 1st International Conference on Cognitive Mobility (CogMob). IEEE, 2022. http://dx.doi.org/10.1109/cogmob55547.2022.10117853.

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Luperto, Matteo, Marta Romeo, Francesca Lunardini, Nicola Basilico, Ray Jones, Angelo Cangelosi, Simona Ferrante i N. Alberto Borghese. "Digitalized Cognitive Assessment mediated by a Virtual Caregiver". W Twenty-Seventh International Joint Conference on Artificial Intelligence {IJCAI-18}. California: International Joint Conferences on Artificial Intelligence Organization, 2018. http://dx.doi.org/10.24963/ijcai.2018/856.

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The ageing of the population deeply impacts on the social costs relative to health care. The use of modern technologies is one of the most promising approaches, under current study, to reduce such impact. In this demonstration, we propose a framework that can be employed for at-home assessment of Mild Cognitive Impairment (MCI). It is composed by a set of digitalized cognitive tests, developed from their paper-and-pencil counterparts, and by a Virtual Caregiver, which oversees the test execution and provides instructions.
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Maharani, A., N. Pendleton, G. Tampubolon, J. Nazroo i P. Dawes. "P07 Sensory impairments and cognitive ageing: findings from 11 european countries". W Society for Social Medicine, 61st Annual Scientific Meeting, University of Manchester, 5–8 September 2017. BMJ Publishing Group Ltd, 2017. http://dx.doi.org/10.1136/jech-2017-ssmabstracts.109.

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Ajnakina, Olesya, Robin Murray, Andrew Steptoe i Dorina Cadar. "OP01 The long-term effects of a polygenetic predisposition to general cognition on healthy cognitive ageing: evidence from the English longitudinal study of ageing". W Society for Social Medicine Annual Scientific Meeting Abstracts. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/jech-2022-ssmabstracts.1.

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Xie, Wuxiang, Fanfan Zheng, Yutong Cai, Xiaobo Han, Yanjun Ma, Rong Hua i Lixin Xie. "Reduced lung function and cognitive decline in ageing: a longitudinal cohort study". W ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.4186.

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Low, Dorrain. "Identification of Dietary Modulators of Cognitive Function in Ageing Using Metabolomics Discovery". W The 2nd International Electronic Conference on Metabolomics. Basel, Switzerland: MDPI, 2017. http://dx.doi.org/10.3390/iecm-2-04982.

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Goumopoulos, Christos. "An Ontology based Game Platform for Mild Cognitive Impairment Rehabilitation". W 6th International Conference on Information and Communication Technologies for Ageing Well and e-Health. SCITEPRESS - Science and Technology Publications, 2020. http://dx.doi.org/10.5220/0009793501300141.

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Wei, Yiran, Xi Chen, Carola-Bibiane Schönlieb, Stephen J. Price i Chao Li. "Predicting Conversion of Mild Cognitive Impairment to Alzheimer’s Disease by Modelling Healthy Ageing Trajectories". W 2023 IEEE 20th International Symposium on Biomedical Imaging (ISBI). IEEE, 2023. http://dx.doi.org/10.1109/isbi53787.2023.10230694.

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Caminero, Raúl Velasco, Luis A. Méndez-Herrero, Francisco J. Díaz-Pernas, Juan Calabia del Campo, Míriam Antón Rodríguez i Mario Martínez-Zarzuela. "Telekin - Tele-rehabilitation System for Musculoskeletal and Cognitive Disorders using Natural Movement Interface Devices". W 3rd International Conference on Information and Communication Technologies for Ageing Well and e-Health. SCITEPRESS - Science and Technology Publications, 2017. http://dx.doi.org/10.5220/0006366701980203.

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Raporty organizacyjne na temat "Cognitive ageing"

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Céline, De Looze, Joanne Feeney i Rose Anne Kenny. The CANDID initiative. Leveraging Cognitive Ageing Dementia Data from Around the World. The Irish Longitudinal Study on Ageing, kwiecień 2021. http://dx.doi.org/10.38018/tildare.2021-03.

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Fang, Mei Lan, Judith Sixsmith, Jacqui Morris, Chris Lim, Morris Altman, Hannah Loret, Rayna Rogowsky, Andrew Sixsmith, Rebecca White i Taiuani Marquine Raymundo. AgeTech, Ethics and Equity: Towards a Cultural Shift in AgeTech Ethical Responsibility. University of Dundee, 2023. http://dx.doi.org/10.20933/100001292.

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Population ageing is a global phenomenon which presents major challenges for the provision of care at home and in the community (ONS, 2018). Challenges include the human and economic costs associated with increasing numbers of older people with poor physical and mental health, loneliness, and isolation challenges (Mihalopoulos et al., 2020). The global ageing population has led to a growth in the development of technology designed to improve the health, well-being, independence, and quality of life of older people across various settings (Fang, 2022). This emerging field, known as “AgeTech,” refers to “the use of advanced technologies such as information and communications technologies (ICT’s), technologies related to e-health, robotics, mobile technologies, artificial intelligence (AI), ambient systems, and pervasive computing to drive technology-based innovation to benefit older adults” (Sixsmith, et al., 2020 p1; see also Pruchno, 2019; Sixsmith, Sixsmith, Fang, and Horst, 2020). AgeTech has the potential to contribute in positive ways to the everyday life and care of older people by improving access to services and social supports, increasing safety and community inclusion; increasing independence and health, as well as reducing the impact of disability and cognitive decline for older people (Sixsmith et al, 2020). At a societal level, AgeTech can provide opportunities for entrepreneurs and businesses (where funding and appropriate models exist) (Akpan, Udoh and Adebisi, 2022), reduce the human and financial cost of care (Mihalopoulos et al., 2020), and support ageing well in the right place (Golant, 2015).
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Amduka, Mohammed, Jon Russo, Krishna Jha, Andre DeHon, Richard Lethin, Jonathan Springer, Rajit Manohar, Rami Melhem, Bob Wray i Christian Lebiere. The Design of a Polymorphous Cognitive Agent Architecture (PCAA). Fort Belvoir, VA: Defense Technical Information Center, maj 2008. http://dx.doi.org/10.21236/ada481982.

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Luan, Sisi, Wenke Cheng, Chenglong Wang, Hongjian Gong i Jianbo Zhou. Impact of glucagon-like peptide 1 analogs on cognitive function among patients with type 2 diabetes mellitus. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, czerwiec 2022. http://dx.doi.org/10.37766/inplasy2022.6.0015.

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Review question / Objective: Diabetes is an independent risk factor for cognitive impairment. Little is known regarding the neuroprotective effects of glucagon-like peptide 1 (GLP-1) analogs on type 2 diabetes mellitus (T2DM).Here, the study aim to assess the impact of GLP-1 on general cognition function among patients with T2DM. Eligibility criteria: Inclusion criteria were as follows: (1) an original article was recently published in English, (2) the population included subjects diagnosed with diabetes at baseline, (3) GLP-1 analogs is a single formulation rather than a fixed dose combination, (4) GLP-1 analogs were compared with no GLP-1 use or placebo or self-control before treatment, (5) the duration of antidiabetic agent use was 12 weeks or more, and (6) it provided quantitative measures of general cognitive function assessed by MMSE or MoCA. Exclusion criteria were as follows: (1) the publication was a review, case report, animal study, or letter to the editor, (2) the study did not clearly define clinical outcomes, (3) the authors could not provide valid data after being contacted, (4) duplicated data.
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Бакум, З. П., i Л. О. Цвіркун. Activation of Cognitive Activity of Future Engineers During Graphical Training. Криворізький державний педагогічний університет, 2014. http://dx.doi.org/10.31812/0564/430.

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The article shows that graphic problems are powerful source and stimulating agent motivating the students for active cognitive and creative work during study of graphical disciplines; methods and techniques promoting the effectiveness of graphical preparation of future engineers, which are directed to both personality development and his further professional establishment, are suggested.
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Kwon, Wi-Suk, Veena Chattaraman i Juan Gilbert. Virtual Agent Locus of Control: Cognitive Assistance for Older Consumers’ Online Shopping. Ames: Iowa State University, Digital Repository, 2013. http://dx.doi.org/10.31274/itaa_proceedings-180814-654.

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Zachary, Wayne, Thomas Santarelli, Joan Ryder i James Stokes. Developing a Multi-Tasking Cognitive Agent Using the COGNET/iGEN Integrative Architecture. Fort Belvoir, VA: Defense Technical Information Center, grudzień 2000. http://dx.doi.org/10.21236/ada416891.

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Fiore, Stephen M., Florian Jentsch, Eduardo Salas i Neal Finkelstein. Cognition, Teams, and Augmenting Team Cognition: Understanding Memory Failures in Distributed Human-Agent Teams. Fort Belvoir, VA: Defense Technical Information Center, styczeń 2005. http://dx.doi.org/10.21236/ada523371.

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Sotnik, Garry. SOSIEL: A Cognitive, Multi-Agent, and Knowledge-Based Platform for Modeling Boundedly-Rational Decision-Making. Portland State University Library, styczeń 2000. http://dx.doi.org/10.15760/etd.6123.

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