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Artykuły w czasopismach na temat "Code with t-availability"
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Lu, Yanbo, Xinji Liu, and Shutao Xia. "On the Single-Parity Locally Repairable Codes with Multiple Repairable Groups." Information 9, no. 11 (2018): 265. http://dx.doi.org/10.3390/info9110265.
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Locally repairable codes (LRCs) are a new family of erasure codes used in distributed storage systems which have attracted a great deal of interest in recent years. For an [ n , k , d ] linear code, if a code symbol can be repaired by t disjoint groups of other code symbols, where each group contains at most r code symbols, it is said to have availability- ( r , t ) . Single-parity LRCs are LRCs with a constraint that each repairable group contains exactly one parity symbol. For an [ n , k , d ] single-parity LRC with availability- ( r , t ) for the information symbols (single-parity LRCs), the minimum distance satisfies d ≤ n - k - ⌈ k t / r ⌉ + t + 1 . In this paper, we focus on the study of single-parity LRCs with availability- ( r , t ) for information symbols. Based on the standard form of generator matrices, we present a novel characterization of single-parity LRCs with availability t ≥ 1 . Then, a simple and straightforward proof for the Singleton-type bound is given based on the new characterization. Some necessary conditions for optimal single-parity LRCs with availability t ≥ 1 are obtained, which might provide some guidelines for optimal coding constructions.
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Häkkinen, Antti, Juha Koiranen, Julia Casado, et al. "qSNE: quadratic rate t-SNE optimizer with automatic parameter tuning for large datasets." Bioinformatics 36, no. 20 (2020): 5086–92. http://dx.doi.org/10.1093/bioinformatics/btaa637.
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Abstract Motivation Non-parametric dimensionality reduction techniques, such as t-distributed stochastic neighbor embedding (t-SNE), are the most frequently used methods in the exploratory analysis of single-cell datasets. Current implementations scale poorly to massive datasets and often require downsampling or interpolative approximations, which can leave less-frequent populations undiscovered and much information unexploited. Results We implemented a fast t-SNE package, qSNE, which uses a quasi-Newton optimizer, allowing quadratic convergence rate and automatic perplexity (level of detail) optimizer. Our results show that these improvements make qSNE significantly faster than regular t-SNE packages and enables full analysis of large datasets, such as mass cytometry data, without downsampling. Availability and implementation Source code and documentation are openly available at https://bitbucket.org/anthakki/qsne/. Supplementary information Supplementary data are available at Bioinformatics online.
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Galletly, G. D., and J. Błachut. "Torispherical Shells under Internal Pressure—Failure due to Asymmetric Plastic Buckling or Axisymmetric Yielding." Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science 199, no. 3 (1985): 225–38. http://dx.doi.org/10.1243/pime_proc_1985_199_117_02.
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In the diameter-to-thickness range 250 < D/t < 1000, internally pressurized torispherical shells can fail either by plastic buckling or by axisymmetric yielding. However, the present Code rules cater only for the axisymmetric yielding mode and they also restrict the D/t ratios to being less than 500. The rules are based on limit analysis results and these can be conservative for this problem. With regard to internal pressure buckling, there are as yet no design rules in either the American or the British pressure vessel Codes to prevent its occurrence. To provide guidance for a more accurate formulation of design rules for both of these failure modes over the range 300 < D/t < 1500, the authors have made a series of calculations to determine the values of Pcr (the internal buckling pressure) and pc (the axisymmetric yielding pressure) for perfect torispherical shells. The availability of these results, obtained with a finite-deflection shell theory, enables curves to be drawn showing when buckling is the controlling failure mode and when axisymmetric yield controls. A comparison is also made, for D/t < 600, between the controlling failure pressures mentioned above and the Drucker-Shield limit pressures. The ratio between the former and the latter varied between 1.2 and 1.8, depending on the geometry of the shell and the magnitude of the yield point, σyp. Considerable economies in the designs of many torispherical shells could, therefore, be achieved if the relevant sections of the Codes were to be modified to take advantage of the foregoing results. The controlling failure pressure curves also indicate how Code rules to prevent plastic buckling for D/t > 500 might be formulated. For the benefit of designers, the numerical values of pcr and pc were transformed, using curve-fitting techniques, into simple approximate equations. Although these equations are for perfect torispherical shells, they should be very beneficial when analysing the related problems of fabricated torispheres in practice.
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Rega, Paul, Shaun Vallejo, John Accumanno, and Brian Fink. "The Integration of a Unique QR® Code and Video to Improve the Correct Application of a Hemorrhage-control Tourniquet by a Naïve Population - A Feasibility Study." Prehospital and Disaster Medicine 34, s1 (2019): s142. http://dx.doi.org/10.1017/s1049023x19003145.
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Introduction:The use of tourniquets by the civilian population has been deemed a critical aspect of the initial response during an active shooter situation. Tourniquet deployment in public-access must be accompanied by education. Studies indicate that the act itself is not an intuitive process and enclosed instructions may be inadequate. However, civilians for diverse reasons may not avail themselves of accepted training programs.Aim:To develop an alternative means of “Just-In-Time” education to enable a naïve responder to apply a commercial tourniquet efficaciously.Methods:A video (~40 seconds long) was created highlighting the actual application of a C-A-T® (Combat Application Tourniquet) on a human model. It was uploaded to YouTube on a public channel. A QR® code was generated using https://www.qr-code-generator.com, embedding the link for the YouTube® video. An appropriately-sized QR® code was printed and applied with packaging tape (Scotch®) to the exterior wrapping of a C-A-T® device. The C-A-T® with code was then accessed with the iPhone®.Results:With the iPhone® camera app activated and focused on the C-A-T’s QR® code, a request popped-up to open “YouTube.com” in Safari. When pressed, the full-screen video appeared immediately with audio of excellent quality.Discussion:The use of a QR® code and its video link is a feasible option to provide “Just-In-Time” training to a naïve civilian population who are responding to an active shooter situation. This offers the naïve responder two options of immediate education: the enclosed instructions and the QR® code. Redundancy in communications is essential in any emergency response. An important limitation of this innovation is the inability to obtain Internet® access and therefore, the availability of the enclosed instructions is still critical. Research to prove that this innovation will allow the application of a tourniquet to proceed expeditiously with few errors is currently underway.
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Sturm, Gregor, Tamas Szabo, Georgios Fotakis, et al. "Scirpy: a Scanpy extension for analyzing single-cell T-cell receptor-sequencing data." Bioinformatics 36, no. 18 (2020): 4817–18. http://dx.doi.org/10.1093/bioinformatics/btaa611.
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Abstract Summary Advances in single-cell technologies have enabled the investigation of T-cell phenotypes and repertoires at unprecedented resolution and scale. Bioinformatic methods for the efficient analysis of these large-scale datasets are instrumental for advancing our understanding of adaptive immune responses. However, while well-established solutions are accessible for the processing of single-cell transcriptomes, no streamlined pipelines are available for the comprehensive characterization of T-cell receptors. Here, we propose single-cell immune repertoires in Python (Scirpy), a scalable Python toolkit that provides simplified access to the analysis and visualization of immune repertoires from single cells and seamless integration with transcriptomic data. Availability and implementation Scirpy source code and documentation are available at https://github.com/icbi-lab/scirpy. Supplementary information Supplementary data are available at Bioinformatics online.
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Tyagi, Ruchi, and Suresh Vishwakarma. "Prospect of low-cost energy conservation in residential energy consumption." International Journal of Power Electronics and Drive Systems (IJPEDS) 12, no. 4 (2021): 2403. http://dx.doi.org/10.11591/ijpeds.v12.i4.pp2403-2413.
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The energy sector of trinidad and tobago (T&amp;T), with its nationally determined contributions (NDCs), is still struggling for its place in mainstream academic literature. The review paper aims to identify the prospects of low-cost energy conservation measures in the residential sector of T&amp;T. The review follows a four-step review methodology to serve as a basis for creating policy and practice guidelines. First, review articles are checked for their quality on a 5-point scale on the mixed methods appraisal tool (MMAT) to check the quality of review articles. Second, Microsoft Excel, R (RQDA) package, and Voyant tools have been used to index code, analyse, and visualise data. The research trends on small islands developing states (SIDS) energy aspect in general and T&amp;T specifically highlight the critical role of energy challenges related to economic and social development, emphasising technology, infrastructure development, and funds availability. Awareness of low-cost energy conservation measures has a high prospect in reducing residential consumption and balancing demand-side management. This paper contributes to facilitating policy direction on energy efficiency and energy conservation for T&amp;T and other SIDS.
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Hoot, Bradley, and Shane Ebert. "The That-Trace Effect: Evidence from Spanish–English Code-Switching." Languages 6, no. 4 (2021): 189. http://dx.doi.org/10.3390/languages6040189.
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The that-trace effect is the fact that many languages (like English) ban the extraction of embedded-clause subjects but not objects over an overt complementizer like that, while many other languages (like Spanish) allow such extractions. The effect and its cross-linguistic variation have been the subject of intense research but remain largely a mystery, with no clear consensus on their underpinnings. We contribute novel evidence to these debates by using Spanish–English code-switching (the use of two languages in one sentence) to test five contemporary theoretical accounts of the that-trace effect. We conducted a formal acceptability judgment experiment, manipulating the extracted argument and code-switch site to test different combinations of linguistic features. We found that subject extraction is only permitted in Spanish–English code-switching when both the C head (que ‘that’) and the T head (i.e., the verb) are in Spanish, but not when either functional head is in English. Our results demonstrate indirect support for two of the five theories we test, failing to support the other three. Our findings also provide new evidence in favor of the view that the that-trace effect is tightly linked to the availability of post-verbal subjects. Finally, we outline how our results can narrow the range of possible theoretical accounts, demonstrating how code-switching data can contribute to core questions in linguistic theory.
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Aliverti, Emanuele, Jeffrey L. Tilson, Dayne L. Filer, et al. "Projected t-SNE for batch correction." Bioinformatics 36, no. 11 (2020): 3522–27. http://dx.doi.org/10.1093/bioinformatics/btaa189.
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Abstract Motivation Low-dimensional representations of high-dimensional data are routinely employed in biomedical research to visualize, interpret and communicate results from different pipelines. In this article, we propose a novel procedure to directly estimate t-SNE embeddings that are not driven by batch effects. Without correction, interesting structure in the data can be obscured by batch effects. The proposed algorithm can therefore significantly aid visualization of high-dimensional data. Results The proposed methods are based on linear algebra and constrained optimization, leading to efficient algorithms and fast computation in many high-dimensional settings. Results on artificial single-cell transcription profiling data show that the proposed procedure successfully removes multiple batch effects from t-SNE embeddings, while retaining fundamental information on cell types. When applied to single-cell gene expression data to investigate mouse medulloblastoma, the proposed method successfully removes batches related with mice identifiers and the date of the experiment, while preserving clusters of oligodendrocytes, astrocytes, and endothelial cells and microglia, which are expected to lie in the stroma within or adjacent to the tumours. Availability and implementation Source code implementing the proposed approach is available as an R package at https://github.com/emanuelealiverti/BC_tSNE, including a tutorial to reproduce the simulation studies. Contact aliverti@stat.unipd.it
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Isacchini, Giulio, Carlos Olivares, Armita Nourmohammad, Aleksandra M. Walczak, and Thierry Mora. "SOS: online probability estimation and generation of T-and B-cell receptors." Bioinformatics 36, no. 16 (2020): 4510–12. http://dx.doi.org/10.1093/bioinformatics/btaa574.
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Abstract Summary Recent advances in modelling VDJ recombination and subsequent selection of T- and B-cell receptors provide useful tools to analyse and compare immune repertoires across time, individuals and tissues. A suite of tools—IGoR, OLGA and SONIA—have been publicly released to the community that allow for the inference of generative and selection models from high-throughput sequencing data. However, using these tools requires some scripting or command-line skills and familiarity with complex datasets. As a result, the application of the above models has not been available to a broad audience. In this application note, we fill this gap by presenting Simple OLGA & SONIA (SOS), a web-based interface where users with no coding skills can compute the generation and post-selection probabilities of their sequences, as well as generate batches of synthetic sequences. The application also functions on mobile phones. Availability and implementation SOS is freely available to use at sites.google.com/view/statbiophysens/sos with source code at github.com/statbiophys/sos.
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Alonsozana, G. L., and R. H. Christenson. "The case for cardiac troponin T: marker for effective risk stratification of patients with acute cardiac ischemia." Clinical Chemistry 42, no. 5 (1996): 803–8. http://dx.doi.org/10.1093/clinchem/42.5.803.
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Abstract Availability of markers such as cardiac troponin T (cTnT) has brought new insights into ischemic heart disease (IHD). cTnT is a distinct protein that differs from other markers in biological function, molecular mass, and cytosolic pool. cTnT has been utilized for diagnosis of acute myocardial infarction (AMI) and risk stratification of patients with IHD. For AMI diagnosis, cTnT showed high sensitivity (94-100%) but generally lower specificity (46-99%), possibly because of increases in non-AMI patients with minor myocardial damage. Outcome studies have demonstrated that IHD patients with increased cTnT are at significantly greater risk for cardiac events; revascularization in patients with increased cTnT may improve outcome. Estimated costs for batched ES 300 cTnT results and for a cTnT rapid assay run "on demand" were $17.48 and $21.65, respectively. cTnT currently has no specific common procedure test code; expected reimbursement is $18.32 for the ES 300 and is not established for the rapid assay.