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Moore, Sandra. "Dynamics of cholera epidemics in Haiti and Africa". Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM5505/document.
Pełny tekst źródłaCholera is an acute diarrheal disease caused by consumption of water or food contaminated with toxigenic Vibrio cholerae. According to the "cholera paradigm", the disease is contracted by exposure to environmental reservoirs of V. cholerae, with outbreaks driven directly by climatic factors. However, as recent findings argue against this dogma, we aimed to elucidate the dynamics of cholera outbreaks in three global foci: Haiti, Democratic Republic of the Congo (DRC) and West Africa. We combined spatiotemporal analysis of epidemics with genetic assessment of V. cholerae isolates. In Haiti, we assessed whether outbreak re-emergence during the rainy season was due to toxigenic V. cholerae O1 strains that have settled into the aquatic environment. Instead, we found that the re-emergence of outbreaks was likely due to persisting outbreaks during the dry season that were insufficiently controlled, rather than an environmental reservoir of V. cholerae O1. In West Africa, our study revealed that Accra, Ghana was the hotspot of cholera in the entire region of West Africa, west of Nigeria. The Accra water network likely played a role in rapid diffusion of V. cholerae throughout the city. Cholera outbreaks spread from Accra into other countries in a wave-like fashion. Distinct outbreaks were linked via migration of at-risk populations, such as certain fishermen. In conclusion, our global reflection of cholera epidemics in these three distinct foci provides a coherent vision of the mechanisms of cholera emergence and diffusion
Nygren, Erik. "A mouse model for direct evaluation of cholera vaccines /". Göteborg : Dept. of Microbiology and immunology, Institute of Biomedicine, The Sahlgrenska Academy at University of Gothenburg, 2009. http://hdl.handle.net/2077/19376.
Pełny tekst źródłaLe, Roux Wouter Jacobus. "Population dynamics of Vibrio cholerae in the Vaal Barrage". Pretoria : [s.n.], 2005. http://upetd.up.ac.za/thesis/available/etd-02162007-175110.
Pełny tekst źródłaOcchino, Deborah Ann. "Vibrio cholerae iron transport : characterization of two tonB systems and components of a heme transport system /". Digital version accessible at:, 1998. http://wwwlib.umi.com/cr/utexas/main.
Pełny tekst źródłaFalklind, Jerkérus Susanna. "Vibrio cholerae O139 : identification, characterization and vaccine strategies /". Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-696-0/.
Pełny tekst źródłaMitchell, Daniel David. "Cholera toxin inhibition and EpsF from its secretion system /". Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/9210.
Pełny tekst źródłaZo, Young-Gun. "Phylogenomic and structural analyses of Vibrio cholerae populations and endemic cholera". College Park, Md. : University of Maryland, 2005. http://hdl.handle.net/1903/3090.
Pełny tekst źródłaThesis research directed by: Marine-Estuarine-Environmental Sciences. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
Bougoudogo, Fiabou. "Contribution à l'étude de l'immunité protectrice contre le choléra : rôle des anticorps vibriocides reconnaissant le polysaccharide spécifique du lipopolysaccharide de "Vibrio cholerae" O:1". Paris 11, 1994. http://www.theses.fr/1994PA114831.
Pełny tekst źródłaLee, Jason J. "Neutrophil responses to Vibrio cholerae autoinducer-1 and structural analogues". Thesis, Griffith University, 2021. http://hdl.handle.net/10072/404172.
Pełny tekst źródłaThesis (Masters)
Master of Medical Research (MMedRes)
School of Medical Science
Griffith Health
Full Text
Salmon, François. "Le choléra au Pérou : leçon pour un continent à risque". Paris 5, 1994. http://www.theses.fr/1994PA05P013.
Pełny tekst źródłaHenze, Charlotte E. "Cholera in Saratov, 1892-1910". Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.436743.
Pełny tekst źródłaFonseca, Ana Glória Rodrigues Sanches da. "Seroprevalência de cólera em área endémica : estudo". Master's thesis, Faculdade de Ciências Médicas. Universidade Nova de Lisboa, 2007. http://hdl.handle.net/10362/4842.
Pełny tekst źródłaSelamolela, S. D. "A retrospective study on the geographical distribution of cholera in Limpopo Province, South Africa". Thesis, University of Limpopo, 2016. http://hdl.handle.net/10386/2420.
Pełny tekst źródłaIntroduction: During mid-November 2008, eleven acute watery diarrhoea cases with the suspicion of cholera like symptoms were detected by a diarrhoea surveillance system at Musina Hospital in Vhembe district - Limpopo Province, South Africa. These cases included eight Zimbabwean and three South African citizens. Laboratory test performed on stool specimens confirmed Vibrio cholerae serogroup 01 Ogawa as the causative pathogen for these reported acute watery diarrhoea cases. Within eight weeks of its onset, the outbreak spread to all the five districts of Limpopo. So far between 15 November 2008 and 01 June 2009, the cumulative number of cases of acute watery diarrhoea reported from five districts of Limpopo Province stands at 4634 including 30 confirmed cholera deaths with an overall case fatality rate of 0.65%. Of these reported cases, Vibrio cholerae has been laboratory confirmed in 656 samples. Methodology: A database was received from the Limpopo Department of Health having all reported cholera cases during the 2008 and 2009 outbreak in Limpopo Province. The data was analysed using STATA statistical software version 12 for windows (STATA Corporation, College Station, Texas). Results: The cholera affected all ages, but the geographic distribution of the disease was very heterogeneous in Limpopo Province. The highest and lowest numbers of cases were reported in Capricorn and Mopani districts, respectively. The majority of the cases 55% (N=2 542) were females. Children less than five years of age 14.2% (N=652) were less affected by the disease. About 73.8% of the cases were aged between O and 44 years. The first four weeks of cholera outbreak strictly included a day-to-day admixture of Zimbabweans and South Africans presenting in the health facilities. The outbreak then affected most South Africans after week five of the epidemic. Conclusion: The cholera outbreak has affected all the five districts of Limpopo Province in South Africa, and new cases continued to be reported until first week of June 2009. There was a link between the Zimbabwean and South African cholera outbreak in Limpopo province.
Mann, Maretta Clare, i n/a. "Sialylmimetics as Potential Inhibitors fo Vibrio Cholerae Sialidase". Griffith University. Institute for Glycomics, 2004. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20061006.083947.
Pełny tekst źródłaMann, Maretta Clare. "Sialylmimetics as Potential Inhibitors fo Vibrio Cholerae Sialidase". Thesis, Griffith University, 2004. http://hdl.handle.net/10072/367187.
Pełny tekst źródłaThesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Biomolecular and Physical Sciences
Full Text
Kazaji, Dieudonne KA'ngweji. "Factors contributing to the prevalence of cholera during 2008 to 2009 in Vhembe District of Limpopo Province, South Africa". Thesis, University of Limpopo, 2015. http://hdl.handle.net/10386/1616.
Pełny tekst źródłaCholera is an acute enteric infection caused by the ingestion of bacterium Vibrio cholerae present in faecally contaminated water or food. Primarily linked to insufficient access to safe water and proper sanitation, its impact can be even more dramatic in areas where basic environmental infrastructures are disrupted or have been destroyed. The aim of the study was to investigate the factors contributing to the prevalence of cholera and the environmental risk factors associated with cholera in the Vhembe district of Limpopo province between 2008 and 2012. The objectives of the study were to identify environmental risk factors for cholera and to determine the number of cholera cases in the Vhembe district. The study used a quantitative, retrospective and cross-sectional research method. The records of 317 patients who met the study criteria were reviewed using an audit tool. The Statistical Package for Social Sciences (SPSS) version 22 was used to analyze the data. The results revealed that lack of adequate hygiene practices, limited access to safe drinking water, lack of safe food preparation and handling, and inadequate sanitation system are risk factors associated with cholera. The study recommends prevention, control of cholera outbreak and case management. Keywords: Cholera, outbreak, Vibrio cholerae 01 and 0139, Watery diarrhea (ricewater), Prevalence, Risk factors.
Sendzik, Walter. "The 1832 Montreal cholera epidemic : a study in state formation". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ37236.pdf.
Pełny tekst źródłaYáñez, Marissa Elena. "Structural and functional studies of minor pseudopilins from the type 2 secretion system of Vibrio cholerae /". Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/8086.
Pełny tekst źródłaEdwin, Aaron. "Structural and functional studies of the secreted metalloprotease PrtV from Vibrio cholerae". Doctoral thesis, Umeå universitet, Kemiska institutionen, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-84553.
Pełny tekst źródłaHopkins, Brett A. "Fowl cholera in turkeys : vaccination, pathogenicity, and DNA analysis /". free to MU campus, to others for purchase, 1999. http://wwwlib.umi.com/cr/mo/fullcit?p9962544.
Pełny tekst źródłaWehinger, Krafft Richard. "Cholera in Yemen post COVID-19 : A Case Study on the Challenges Humanitarian organizations Face in Ending Cholera". Thesis, Uppsala universitet, Statsvetenskapliga institutionen, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-432710.
Pełny tekst źródłaRebaudet, Stanislas. "Etude dynamique des épidémies de choléra en Afrique et en Haïti et application à la mise en place de stratégies d'élimination". Thesis, Aix-Marseille, 2014. http://www.theses.fr/2014AIXM5055/document.
Pełny tekst źródłaCholera is an epidemic acute watery diarrhea caused by toxigenic bacteria Vibrio cholerae O1. Its environment determinants have been at the source of a popular paradigm. Many recent control strategies have shown little efficiency in Africa or in Haiti, but they could be improved by a better comprehension of the epidemics dynamic. The bibliographic synthesis of environment influences on cholera in Africa highlights the limits of the environmental paradigm on this continent. A multidisciplinary study of the origin of cholera epidemic in Guinea in 2012 strongly suggests it was humanly imported from nearby Sierra Leone. A space-time description of cholera in Mozambique demonstrates heterogeneous transmission patterns and challenges the concept of cholera endemicity. Since its importation in Haiti in October 2010, cholera transmission also exhibits a marked spatio-temporal heterogeneity. Cholera important retraction during the dry season and its absence of significant establishment in the Haitian environment suggest it may be possible to rapidly eliminate cholera in the country, provided that every outbreak focus receives a targeted response. An elimination strategy based on our recommendations is currently implemented by Haitian Ministry of Health, UNICEF and their partners. After spectacular results in 2013 and during the first half of 2014, the situation has slowly deteriorated during the rainy season. However, cholera elimination during the coming dry season remains realistic provided that we succeed in persuading and remobilizing the partners present on the field
Robb, Rhonda Rae. "Risk Factors for Pre-Post Monsoon Cholera Epidemics in Bangladesh from 1992-1994". PDXScholar, 2004. https://pdxscholar.library.pdx.edu/open_access_etds/1691.
Pełny tekst źródłaHayes, Edward. "Fragment based design of cholera toxin inhibitors". Thesis, University of Leeds, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.534749.
Pełny tekst źródłaScobie, Tamara Susan. "The structure and function of cholera toxin". Thesis, University of Edinburgh, 1987. http://hdl.handle.net/1842/19281.
Pełny tekst źródłaCOLUCCI, MANUELA. "Immunomodulatory properties of cholera toxin B subunit". Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2009. http://hdl.handle.net/2108/1019.
Pełny tekst źródłaAntigen-non-specific innate immunity and antigen-specific adaptive immunity synergize to eradicate invading pathogens through the actions of immune cells and their effector proteins, including complement, antibodies, cytokines and cytolytic factors. Adaptive immune responses are induced, coordinated and regulated by dendritic cells (DC). DC initiate immunity by the activation of naïve B and T cells - the effector cells of the adaptive immune system - and by the stimulation of natural killer cells - the crucial cellular instigators of innate resistance. Besides linking innate and adaptive immunity, DC limit excessive, tissue-damaging immune responses in order to prevent autoimmunity and non-essential reactions to innocuous agents through their ability to induce antigen-specific unresponsiveness of lymphocytes in primary and secondary lymphoid tissues by mechanisms that include deletion and induction of regulatory T cells (Tregs). Given the central role of these antigen presenting cells in immunity and tolerance, they are ideal therapeutic targets for pharmacological modulation of immune responses. In the present study, we examined the possibility that recombinant CTB (rCTB) may affect human DC functions in response to toll-like receptor (TLR) stimulation and may induce the generation of DC with the capacity to generate Tregs. CTB - cholera toxin B subunit - is an efficient mucosal carrier molecule for the generation of immune responses to linked antigens, since it facilitates entry into the cell of the CTB-antigen complex by ligation of its surface receptor GM1. There is also good evidence that CTB acts as an immunosuppressant, as it is able to down-modulate human monocyte/macrophage cell line activation and to suppress Th1-type responses. Our findings show that rCTB partially prevents the lipopolysaccharide (LPS)-induced maturation process of monocyte-derived DC (MDDC) and decreases their interleukin-12p70 (IL-12p70) production with no relevant effect on IL-10 production. LPS-stimulated MDDC pre-treated with rCTB are able to promote the induction of low proliferating T cells, which show an enhanced IL-10 production associated with a reduced interferon-γ (IFN-γ) production and the same high levels of trasforming growth factor-β (TGF-β) as the control. These T cells suppress proliferation of activated autologous T cells. Transwell experiments and blockade of IL-10R and TGF-β showed that the immunomodulatory effect is mediated by soluble factors. Thus, T cells induced by rCTB-conditioned MDDC acquire a regulatory phenotype and activity similar to those described for IL-10 producing type 1 Tregs (Tr1).
Balmforth, Matthew Royce. "Piggybacking on the cholera toxin : using cholera toxin B chain for the targeted delivery of proteins to motor neurones". Thesis, University of Leeds, 2017. http://etheses.whiterose.ac.uk/20115/.
Pełny tekst źródłaЧемич, Микола Дмитрович, Николай Дмитриевич Чемич, Mykola Dmytrovych Chemych, Андрій Олегович Сніцар, Андрей Олегович Сницарь, Andrii Olehovych Snitsar, Ірина Олександрівна Троцька i in. "Випадок завезеної холери, викликаної V. cholerae О139, у Сумській області". Thesis, Видавництво СумДУ, 2007. http://essuir.sumdu.edu.ua/handle/123456789/3802.
Pełny tekst źródłaSaid, Bengu. "Vibrio cholerae non-O1 and V. mimicus in diarrhoeal disease : a study of virulence factors". Thesis, Open University, 1995. http://oro.open.ac.uk/57564/.
Pełny tekst źródłaSaul-McBeth, Jessica. "Characterization of SipA, A Protein Important for Stress Responses in Vibrio cholerae". University of Toledo Health Science Campus / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=mco1544540466901883.
Pełny tekst źródłaJablonski, Lynn McGonagle. "Development of a cloning system for gene expression in Pasteurella multocida". Diss., This resource online, 1993. http://scholar.lib.vt.edu/theses/available/etd-05042006-164516/.
Pełny tekst źródłaGiebultowicz, Sophia H. Emch Michael. "Cholera transmission in Bangladesh social networks and neighborhoods /". Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2010. http://dc.lib.unc.edu/u?/etd,2956.
Pełny tekst źródłaTitle from electronic title page (viewed Jun. 23, 2010). "... in partial fulfillment of the requirements for the degree of Master of Arts in the Department of Geography." Discipline: Geography; Department/School: Geography.
O'Neal, Claire J. "Structural studies of the cholera toxin catalytic subunit /". Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/8592.
Pełny tekst źródłaChan, Wai-man, i 陳渭雯. "Development of edible vaccines against hog cholera virus". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31227181.
Pełny tekst źródłaVely, Frédéric. "Préparation et caractérisation d'anticorps monoclonaux anti-"Vibrio cholerae" O:1. Contributions à l'étude des bases moléculaires de la vibriocidie et à l'amélioration du diagnostic". Paris 5, 1993. http://www.theses.fr/1993PA05P215.
Pełny tekst źródłaPandit, Kalyan Kumar. "Detection of serotype and potential virulence determinants in Pasteurella multiocida of different host origin". Thesis, University of Surrey, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306277.
Pełny tekst źródłaWebb, Jeanette Helen. "The role of ubiquitin during African swine fever virus infection". Thesis, University of Hertfordshire, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.363507.
Pełny tekst źródłaJones, Huw Dylan. "The role of G-proteins in intracellular signalling mechanisms of wild oat (Avena fatua) aleurone". Thesis, University of Bristol, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337173.
Pełny tekst źródłaCaplet, Nathalie. "Cloning and characterisation of EpsD, a protein required for toxin secretion from Vibrio cholerae". Thesis, University of Bristol, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302104.
Pełny tekst źródłaBonderup, Gerda. ""Cholera-Morbro'er" og Danmark : billeder til det 19. århundredes samfunds- og kulturhistorie /". Aarhus : Aarhus universitetsforlag, 1994. http://catalogue.bnf.fr/ark:/12148/cb36180664x.
Pełny tekst źródłaHof, Suzanne Michelle. "Synthesis of inhibitors for the cholera family of toxins". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0011/NQ59600.pdf.
Pełny tekst źródłaMachin, Darren Christopher. "Engineering cholera toxin for the targeted delivery of oligonucleotides". Thesis, University of Leeds, 2016. http://etheses.whiterose.ac.uk/16635/.
Pełny tekst źródłaCarrel, Margaret A. Emch Michael. "Relationships between flood control and cholera in Matlab, Bangladesh". Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,1945.
Pełny tekst źródłaTitle from electronic title page (viewed Dec. 11, 2008). "... in partial fulfillment of the requirements of the degree of Master of Arts in the Department of Geography." Discipline: Geography; Department/School: Geography.
SCIARAFFIA, ESTER. "Effects of cholera toxin on cells of immune system". Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2009. http://hdl.handle.net/2108/1070.
Pełny tekst źródłaIn this study, we analysed the effects of Cholera Toxin (CT) on cells of immune system. In particular, the mechanisms underling the inhibition of T cell proliferation mediated by CT on human CD4+ and CD8+ T lymphocytes were analysed. We observed that CT prevents the early activation steps of T lymphocytes and that these effects involve the modulation of costimulatory molecules CTLA-4 and CD28. We observed that CT up-regulates the expression of the inhibitory molecule CTLA-4 in resting CD4+ and CD8+ T lymphocytes. The regulation of CTLA-4 expression by CT is at the transcriptional level. Indeed, in cells treated with CT we observed an increase of two mRNA variants coding for the membrane and the soluble CTLA-4 molecules. In parallel with the up-regulation of the inhibitory molecule CTLA-4, CT down-modulates the costimulatory molecule CD28 on CD4+ and CD8+ resting T cells. The increased expression of CTLA-4 plays a role in controlling T cell activation and function as blocking anti-CTLA-4 F(ab’)2 mAbs partially prevents the inhibition mediated by CT. We evaluated the function of CT-pre-treated CD4+ T lymphocytes and we observed that they are able to inhibit the proliferation of autologous T lymphocytes stimulated with anti-CD3 mAbs. It is interesting that this phenomenon is, at least in part, a result of the release of extracellular cAMP. Therefore, by analysing the direct effects exerted by extracellular cAMP as a primary messenger on different cell types, we found that extracellular cAMP inhibits T cell proliferation and that it is able to interfere with the differentiation of monocytes into DCs. Monocytes induced to differentiated into DCs in the presence of extracellular cAMP, do not express CD1a molecules and retain the expression of CD14 acquiring a macrophages-like phenotype. Furthermore, they strongly up-regulate MHC class I and class II and CD86 costimulatory molecules giving rise to an activated population able to stimulate allogeneic T cell response. In addition, they produce a distinct pattern of cytokines upon maturation stimuli, they are unable to produce TNFα and IL-12 and they release high amount of IL-6 and IL-10. Furthermore, monocytes differentiated in the presence of cAMP show a reduced capacity of inducing the differentiation of IFNγ producing CD4+ T lymphocytes. Finally, the mechanisms through which extracellular cAMP can be sensed by the cells were studied. By using different adenosine receptors antagonists, we found that an extracellular cAMP-adenosine pathway is involved in the effects mediated by exogenous cAMP, suggesting that extracellular cAMP acting as primary messenger can be sensed by the cells of immune system and can modulate their functions.
Chow, Kwok-ming. "Cholera prevention as social control? : Hong Kong in the late 1960s /". Hong Kong : University of Hong Kong, 1997. http://sunzi.lib.hku.hk/hkuto/record.jsp?B18649981.
Pełny tekst źródłaJahan, Nasrin. "Structural studies of Vibrio cholerae quorum sensing proteins". Thesis, University of St Andrews, 2011. http://hdl.handle.net/10023/2565.
Pełny tekst źródłaTorres, Andre L. "An inexpensive, plant-derived, dual vaccine for rotavirus and cholera". Honors in the Major Thesis, University of Central Florida, 2009. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/1333.
Pełny tekst źródłaBachelors
Medicine
Biotechnology
Burress, Helen. "Modulation of cholera toxin structure and function by host proteins". Doctoral diss., University of Central Florida, 2014. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/6251.
Pełny tekst źródłaPh.D.
Doctorate
Molecular Biology and Microbiology
Medicine
Biomedical Sciences
LIMA, BEATRIZ DE SOUZA. "LOVE IN THE TIME OF CHOLERA: AGGRESSIVENESS, SUBJECTIVITY AND CULTURE". PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2007. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=9985@1.
Pełny tekst źródłaA presente tese tem como tema uma investigação sobre a participação da agressividade e da cultura nos processos de subjetivação e do tornar-se pessoa. Em um primeiro momento buscou-se estabelecer a distinção entre agressividade e violência no contexto da cultura, da teoria psicanalítica e na obra D.W. Winnicott. Em seguida efetuou-se um estudo sobre a teoria winnicottiana da agressividade que procurou compreender a sua evolução situando-a em relação à três contextos teóricos distintos: o inicial, o da teoria do desenvolvimento emocional e o dos objetos e fenômenos transicionais. Por fim, a partir do trabalho realizado pela ONG - Casa da Árvore, e dos conceitos de provisão ambiental, falha ambiental e tendência anti-social, elaborou-se uma reflexão sobre as manifestações agressivas e destrutivas, no âmbito de um dispositivo terapêutico que promove o atendimento coletivo de crianças de 6 a 12 anos, na comunidade do Morro do Chapéu Mangueira, na cidade do Rio de Janeiro. Defende-se a tese de que a promoção de uma política de atenção à infância resulta em um trabalho efetivo de prevenção em saúde mental, principalmente, no tocante à prevenção da violência, da delinqüência, dos distúrbios de conduta de caráter compulsivo e das doenças psicóticas.
The present thesis has as subject an inquiry on the participation of the aggressiveness and the culture in the processes of becoming a person. At a first moment was established the distinction between aggressiveness and violence in the context of the culture, the psychoanalysis theory and also considering the work of D.W. Winnicott. After that a study was done on the Winnicott´s theory of the aggressiveness that tries to understand its evolution pointing it out in relation to the three theoretical contexts: the initial context, the context of the emotional development theory and the context of the transicional objects and phenomena. Finally, from the experience of the non-governmental organization - Casa da Árvore - , and from the concepts of environmental provision and fails and of antisocial tendency, a reflection was elaborated on the manifestations of aggressiveness development disturbs, in the scope of a therapeutic device that promotes the collective assistance to children from 6 to 12 years old, in the community of the Morro do Chapéu Mangueira, in the city of Rio de Janeiro. We support that the promotion of politics of attention to childhood results in an extraordinary mental health prevention, mainly in regards to the prevention of the anti-social behavior and of the psychotic illnesses.
Eckhoff, Grace. "Evaluation of a Novel Inaba Cholera Conjugate Vaccine in Mice". Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:17295897.
Pełny tekst źródła