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Artykuły w czasopismach na temat "Cellular differentiation"

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Yap, Lynn, Hwee Goon Tay, Mien T. X. Nguyen, Monica S. Tjin i Karl Tryggvason. "Laminins in Cellular Differentiation". Trends in Cell Biology 29, nr 12 (grudzień 2019): 987–1000. http://dx.doi.org/10.1016/j.tcb.2019.10.001.

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Soraisam, Purnabati, G. TempySangma, Th Naranbabu Singh, N. Saratchandra Singh i M. Shyamo Singh. "Cellular Differentiation of Developing Pancreas in Human Fetuses of Manipuri Origin". Scholars Journal of Applied Medical Sciences 4, nr 7 (lipiec 2016): 2332–37. http://dx.doi.org/10.21276/sjams.2016.4.7.5.

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Kretz, Markus. "TINCR, staufen1, and cellular differentiation". RNA Biology 10, nr 10 (październik 2013): 1597–601. http://dx.doi.org/10.4161/rna.26249.

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Kirsch, Thorsten. "Osteoarthritis: a cellular differentiation defect?" Current Opinion in Orthopaedics 14, nr 5 (październik 2003): 356–61. http://dx.doi.org/10.1097/00001433-200310000-00009.

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Fusenig, N. E., D. Breitkreutz, H. J. Stark, P. Tomakidi, W. Peter i P. Boukamp. "Cellular differentiation and tumor progression". Melanoma Research 3 (wrzesień 1993): 3. http://dx.doi.org/10.1097/00008390-199309002-00004.

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SOHAL, R. S., R. G. ALLEN i C. NATIONS. "Oxidative Stress and Cellular Differentiation". Annals of the New York Academy of Sciences 551, nr 1 Membrane in C (grudzień 1988): 59–73. http://dx.doi.org/10.1111/j.1749-6632.1988.tb22320.x.

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Levine, Joe H., Michelle E. Fontes, Jonathan Dworkin i Michael B. Elowitz. "Pulsed Feedback Defers Cellular Differentiation". PLoS Biology 10, nr 1 (31.01.2012): e1001252. http://dx.doi.org/10.1371/journal.pbio.1001252.

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Misago, Noriyuki, Toshimi Satoh i Yutaka Narisawa. "Cellular neurothekeoma with histiocytic differentiation". Journal of Cutaneous Pathology 31, nr 8 (22.07.2004): 568–72. http://dx.doi.org/10.1111/j.0303-6987.2004.00223.x.

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Sager, B., i D. Kaiser. "Spatial restriction of cellular differentiation." Genes & Development 7, nr 9 (1.09.1993): 1645–53. http://dx.doi.org/10.1101/gad.7.9.1645.

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Langdale, Jane A. "Cellular differentiation in the leaf". Current Opinion in Cell Biology 10, nr 6 (grudzień 1998): 734–38. http://dx.doi.org/10.1016/s0955-0674(98)80115-4.

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Rozprawy doktorskie na temat "Cellular differentiation"

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Glover, Beverley Jane. "Cellular differentiation in plants". Thesis, University of East Anglia, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338247.

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Brero, Alessandro. "Nuclear topology during cellular differentiation in mouse". Diss., [S.l.] : [s.n.], 2004. http://edoc.ub.uni-muenchen.de/archive/00002625/.

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Leahy, Rachel A. "Signal Transduction and Cellular Differentiation in Airway Epithelium". Kent State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=kent1352673026.

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Yu, Lu. "Multiple signaling pathways cooperate to activate skeletal muscle differentiation /". View abstract or full-text, 2005. http://library.ust.hk/cgi/db/thesis.pl?BICH%202005%20YU.

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Chano, Laura. "Emdogain regulation of cellular differentiation in wounded rat periodontium". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ63000.pdf.

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Parker, Emma. "The role of insulin-like growth factor binding proteins (IGFBPs) in the pathogenesis of pulmonary fibrosis". Thesis, Keele University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269130.

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Clarke, A. R. "Retroviral mediated expression of B-galactosidase in mouse cells". Thesis, University of Cambridge, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303267.

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Dixon, Katherine. "Characterization of the Global and Locus-Specific Regulation of Gene Expression During Early Myogenic Differentiation". Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/35079.

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During cellular differentiation, gene expression is globally regulated through changes in the epigenome. How a single genome can give rise to a diversity of cell and tissue types remains a complex area of investigation, and here we sought to explore the molecular regulation of gene expression during the differentiation of skeletal muscle cells from committed myogenic progenitors. Using a systematic and integrated analysis of global transcriptional and epigenetic data, we characterized the regulation of gene expression in differentiating myoblasts and found that muscle-specific gene expression is regulated through differential activation of tissue-specific regulatory DNA elements by the myogenic transcription factor MyoD. In addition, the genome-wide localization of MyoD, and the mechanisms underlying its function in transcriptional regulation, varies between myogenic progenitors and differentiating myoblasts. Our study explores the recruitment and function of MyoD at regulatory elements of target genes and additionally describes a novel role for ligand-inducible signaling in the regulation of MyoD function and ultimately in myogenic differentiation.
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Berg, Tove. "C/EBP transcription factors in lung cellular differentiation and development /". Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-586-0/.

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Munkley, Jennifer. "The sub-cellular organisation of DNA replication factors during differentiation". Thesis, University of York, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.547361.

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Książki na temat "Cellular differentiation"

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Volvox: Molecular-genetic origins of multicellularity and cellular differentiation. Cambridge, U.K: Cambridge University Press, 1998.

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L, Kirk David. Volvox: Molecular-genetic origins of multicellularity and cellular differentiation. Cambridge, U.K: Cambridge University Press, 2005.

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Ginette, Serrero, i Hayashi Jun, red. Cellular endocrinology: Hormonal control of embryonic and cellular differentiation : proceedings of the First International Symposium on Cellular Endocrinology, held in Lake Placid, New York, August 12-16, 1985. New York: A.R. Liss, 1986.

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Grimes, Gary W. Cellular aspects of pattern formation: The problem of assembly. Basel: Karger, 1991.

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Symposium of the International Prize for Biology. (3rd 1987 Okazaki, Japan). Regulatory mechanisms in developmental processes: Proceedings of the 3rd Symposium of the International Prize for Biology, Okazaki, 27-28 November 1987. Shannon: Elsevier Scientific Publishers Ireland, 1988.

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Condon, Bernadette. Molecular and cellular regulation of the gene encoding adipose differentiation related protein. Dublin: University College Dublin, 1996.

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M, Veneziale Carlo, red. Control of cell growth and proliferation. New York, N.Y: Van Nostrand Reinhold, 1985.

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NATO, Advanced Research Workshop on Signals for Cell Separation in Plants (1988 Turin Italy). Cell separation in plants: Physiology, biochemistry, and molecular biology. Berlin: Springer-Verlag, 1989.

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S, Stein Gary, red. The molecular basis of cell cycle and growth control. New York: J. Wiley, 1998.

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Marina, Bentivoglio, i Spreafico Roberto, red. Cellular thalamic mechanisms: Based on contributions to the symposium held in Verona, Italy, 22-25 August 1987. Amsterdam: Excerpta Medica, 1988.

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Części książek na temat "Cellular differentiation"

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Carlberg, Carsten, i Ferdinand Molnár. "Embryogenesis and Cellular Differentiation". W Human Epigenetics: How Science Works, 63–73. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-22907-8_6.

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Carlberg, Carsten, i Ferdinand Molnár. "Embryogenesis and Cellular Differentiation". W Human Epigenomics, 123–40. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-7614-5_8.

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Roberts, Jeremy A., i Richard Hooley. "Cellular Differentiation and Morphogenesis". W Plant Growth Regulators, 68–79. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4615-7592-4_5.

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Satoh, Ichiro. "Cellular Differentiation-Based Service Adaptation". W Service-Oriented Computing, 582–89. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-25535-9_44.

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Hirata, Fusao, Masakazu Hatanaka, Yuji Wano i Keiichi Matsuda. "Phospholipid Methylation and Cellular Differentiation". W Biological Methylation and Drug Design, 67–74. Totowa, NJ: Humana Press, 1986. http://dx.doi.org/10.1007/978-1-4612-5012-8_6.

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Schindler, Joel. "Molecular and Cellular Aspects of Embryonal Carcinoma Cell Differentiation". W Tumor Cell Differentiation, 123–36. Totowa, NJ: Humana Press, 1987. http://dx.doi.org/10.1007/978-1-4612-4594-0_9.

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Deyrieux, Adeline F., i Van G. Wilson. "Sumoylation in Development and Differentiation". W SUMO Regulation of Cellular Processes, 197–214. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-50044-7_12.

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Deyrieux, Adeline F., i Van G. Wilson. "Sumoylation in Development and Differentiation". W SUMO Regulation of Cellular Processes, 187–99. Dordrecht: Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-90-481-2649-1_11.

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Burke, Zoë D., Gabriela Miron-Buchacra i David Tosh. "Cellular Reprogramming During Mouse Development". W Results and Problems in Cell Differentiation, 291–302. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-30406-4_16.

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Verbeke, Judith A. "Cell Communication and the Coordination of Differentiation". W Cellular Communication in Plants, 99–103. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4757-9607-0_15.

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Streszczenia konferencji na temat "Cellular differentiation"

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Molavi Kakhki, Arash, Abbas Razaghpanah, Rajesh Golani, David Choffnes, Phillipa Gill i Alan Mislove. "Identifying traffic differentiation on cellular data networks". W SIGCOMM'14: ACM SIGCOMM 2014 Conference. New York, NY, USA: ACM, 2014. http://dx.doi.org/10.1145/2619239.2631445.

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"CELLULAR DIFFERENTIATION-BASED APPROACH FOR DISTRIBUTED SYSTEMS". W International Conference on Evolutionary Computation Theory and Applications. SciTePress - Science and and Technology Publications, 2011. http://dx.doi.org/10.5220/0003642701310136.

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Limia, Cintia, Rafaela Reis, Cristiana Solza, Adelmo Gabriel, Ilana Renault, Antonio Di Stefano, Isabelle Plo, Stevens Rehen, Barbara Mor i Martín Bonamino. "TET2 mutation in cellular reprogramming and hematopoietic differentiation". W VI Seminário Anual Científico e Tecnológico. Instituto de Tecnologia em Imunobiológicos, 2018. http://dx.doi.org/10.35259/isi.sact.2019_27184.

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Wan, Leo Q., Sylvia M. Kang, George Eng, X. Lux Lu, B. Bob Huo, Jeffrey Gimble, X. Edward Guo, Van C. Mow i Gordana Vunjak-Novakovic. "Geometric Control of Mechanical Forces and Stem Cell Differentiation". W ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192680.

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How can genetic information be translated to give specific and different spatial patterns of cellular differentiation? This is an important question in developmental biology. The spatial pattern of cellular behavior is generally considered solely dependent on the gradient of morphogens, which are usually soluble and diffusible chemicals. However, cellular function, e.g., proliferation, is found to be quite different even when cells are a few microns apart. Therefore, it has been proposed that tissue form arises as a result of feedback mechanism through mechanical forces, i.e., the tissue form will affect cellular function via mechanical force.
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Wang, Yanjiang, Chengna Yuan i Weifeng Liu. "Cellular Differentiation Algorithm for High Dimensional Numerical Function Optimization". W 2012 Eleventh International Conference on Machine Learning and Applications (ICMLA). IEEE, 2012. http://dx.doi.org/10.1109/icmla.2012.54.

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Schvartzman, Juan Manuel, i Craig B. Thompson. "Abstract 2877: Effects of metabolic stressors on cellular differentiation". W Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-2877.

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Steiner, Till, Yaochu Jin i Bernhard Sendhoff. "Evolving heterochrony for cellular differentiation using vector field embryogeny". W the 12th annual conference. New York, New York, USA: ACM Press, 2010. http://dx.doi.org/10.1145/1830483.1830590.

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Boppart, Stephen A., Gary J. Tearney, Brett E. Bouma, James G. Fujimoto i Mark E. Brezinski. "Optical Coherence Tomography of Embryonic Morphology During Cellular Differentiation". W Advances in Optical Imaging and Photon Migration. Washington, D.C.: Optica Publishing Group, 1996. http://dx.doi.org/10.1364/aoipm.1996.cit231.

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Improved imaging of morphological changes has the potential of offering new insight into the complex process of embryonic development. Optical coherence tomography (OCT), is a new imaging technique for performing in vivo cross-sectional imaging of architectural morphology by measuring backscattered infrared light. This study investigates the application of OCT for imaging developing structure in Xenopus laevis (African frog) and Brachydanio rerio (zebra fish), two developmental biology animal models. Images are compared to corresponding histological preparations. Cross sectional imaging can be performed and structural morphology identified at greater imaging depths than possible with confocal and light microscopy. Repeated OCT imaging may be performed in vivo in order to track structural changes throughout development. Imaging in vivo microscopic embryonic morphology with OCT is a fundamental biological research application for the study of genetic disease.
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Nogueira, Georges, Bruno Baynat i Ahmed Ziram. "A Markovian Model for Mobile Cellular Networks with QoS Differentiation". W 6th International ICST Symposium on Modeling and Optimization. IEEE, 2008. http://dx.doi.org/10.4108/icst.wiopt2008.2988.

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Gongora, Mario, i Maria C. Rodas. "Analysis of organized asymmetry development using artificial cellular differentiation models". W 2009 IEEE Workshop on Evolving and Self-Developing Intelligent Systems (ESDIS). IEEE, 2009. http://dx.doi.org/10.1109/esdis.2009.4938998.

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Raporty organizacyjne na temat "Cellular differentiation"

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Klein, S. B. SEM and x-ray microanalysis of cellular differentiation in Sea Urchin Embryos: a frozen hydrated study. Office of Scientific and Technical Information (OSTI), grudzień 1985. http://dx.doi.org/10.2172/5964745.

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Mirosevich, Janni. Investigating the Role of Hepatocyte Nuclear Factor-3 (HNF-3) Alpha and Beta in Prostate Cancer and Cellular Differentiation. Fort Belvoir, VA: Defense Technical Information Center, styczeń 2006. http://dx.doi.org/10.21236/ada455964.

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Mirosevich, Janni. Investigating the Role of Hepatocyte Nuclear Factor-3 (HNF-3) Alpha and Beta in Prostate Cancer and Cellular Differentiation. Fort Belvoir, VA: Defense Technical Information Center, styczeń 2005. http://dx.doi.org/10.21236/ada431320.

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Bercovier, Herve, Raul Barletta i Shlomo Sela. Characterization and Immunogenicity of Mycobacterium paratuberculosis Secreted and Cellular Proteins. United States Department of Agriculture, styczeń 1996. http://dx.doi.org/10.32747/1996.7573078.bard.

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Our long-term goal is to develop an efficient acellular vaccine against paratuberculosis based on protein antigen(s). A prerequisite to achieve this goal is to analyze and characterize Mycobacterium paratuberculosis (Mpt) secreted and cellular proteins eliciting a protective immune response. In the context of this general objective, we proposed to identify, clone, produce, and characterize: the Mpt 85B antigen and other Mpt immunoreactive secreted proteins, the Mpt L7/L12 ribosomal protein and other immunoreactive cellular proteins, Mpt protein determinants involved in invasion of epithelial cells, and Mpt protein antigens specifically expressed in macrophages. Paratuberculosis is still a very serious problem in Israel and in the USA. In the USA, a recent survey evaluated that 21.6% of the dairy herd were infected with Mpt resulting in 200-250 million dollars in annual losses. Very little is known on the virulence factors and on protective antigens of Mpt. At present, the only means of controlling this disease are culling or vaccination. The current vaccines do not allow a clear differentiation between infected and vaccinated animals. Our long-term goal is to develop an efficient acellular paratuberculosis vaccine based on Mpt protein antigen(s) compatible with diagnostic tests. To achieve this goal it is necessary to analyze and characterize secreted and cellular proteins candidate for such a vaccine. Representative Mpt libraries (shuttle plasmid and phage) were constructed and used to study Mpt genes and gene products described below and will be made available to other research groups. In addition, two approaches were performed which did not yield the expected results. Mav or Mpt DNA genes that confer upon Msg or E. coli the ability to invade and/or survive within HEp-2 cells were not identified. Likewise, we were unable to characterize the 34-39 kDa induced secreted proteins induced by stress factors due to technical difficulties inherent to the complexity of the media needed to support substantial M. pt growth. We identified, isolated, sequenced five Mpt proteins and expressed four of them as recombinant proteins that allowed the study of their immunological properties in sensitized mice. The AphC protein, found to be up regulated by low iron environment, and the SOD protein are both involved in protecting mycobacteria against damage and killing by reactive oxygen (Sod) and nitrogen (AhpC) intermediates, the main bactericidal mechanisms of phagocytic cells. SOD and L7/L12 ribosomal proteins are structural proteins constitutively expressed. 85B and CFP20 are both secreted proteins. SOD, L7/L12, 85B and CFP20 were shown to induce a Th1 response in immunized mice whereas AphC was shown by others to have a similar activity. These proteins did not interfere with the DTH reaction of naturally infected cows. Cellular immunity provides protection in mycobacterial infections, therefore molecules inducing cellular immunity and preferentially a Th1 pathway will be the best candidate for the development of an acellular vaccine. The proteins characterized in this grant that induce a cell-mediated immunity and seem compatible with diagnostic tests, are good candidates for the construction of a future acellular vaccine.
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Sun, Lina, Yanan Han, Hua Wang, Huanyu Liu, Shan Liu, Hongbin Yang, Xiaoxia Ren i Ying Fang. MicroRNAs as Potential Biomarkers for the Diagnosis of Inflammatory Bowel Disease: A Systematic Review and Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, luty 2022. http://dx.doi.org/10.37766/inplasy2022.2.0027.

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Review question / Objective: The purpose of this systematic review was to systematically review the clinical studies regarding miRNAs as diagnostic biomarkers for inflammatory bowel disease and assess the overall diagnostic accuracy of miRNAs. Condition being studied: The symptoms of inflammatory bowel disease (IBD) are highly variable. The diagnosis of IBD must be made through medical history, physical, laboratory, radiologic, endoscopic, and histological examinations. However, these diagnostic techniques are not specific and sometimes even equivocal. Therefore, reliable biomarkers are urgently needed in the diagnosis of IBD. Several clinical and preclinical researches have shown that dysregulated microRNAs (miRNAs) play a crucial role in IBD development. miRNAs, as single-stranded noncoding RNAs that contain 22-24 nucleotides, can post-transcriptionally regulate gene expression by blocking mRNA translation or degrading target mRNAs. miRNAs are widely involved in physiological and pathological cellular processes, such as differentiation, proliferation and apoptosis. Besides, they are stable, noninvasive, and resistant to degradation by ribonucleases, making them valuable targets in the diagnosis, monitoring, prognosis, and treatment of diseases. To date, inconsistent results have been found about miRNA expression profiling in the patients with IBD. Moreover, the diagnostic accuracy of miRNAs for IBD has not been reported in any meta-analysis.
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Eldar, Avigdor, i Donald L. Evans. Streptococcus iniae Infections in Trout and Tilapia: Host-Pathogen Interactions, the Immune Response Toward the Pathogen and Vaccine Formulation. United States Department of Agriculture, grudzień 2000. http://dx.doi.org/10.32747/2000.7575286.bard.

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In Israel and in the U.S., Streptococcus iniae is responsible for considerable losses in various fish species. Poor understanding of its virulence factors and limited know-how-to of vaccine formulation and administration are the main reasons for the limited efficacy of vaccines. Our strategy was that in order to Improve control measures, both aspects should be equally addressed. Our proposal included the following objectives: (i) construction of host-pathogen interaction models; (ii) characterization of virulence factors and immunodominant antigens, with assessment of their relative importance in terms of protection and (iii) genetic identification of virulence factors and genes, with evaluation of the protective effect of recombinant proteins. We have shown that two different serotypes are involved. Their capsular polysaccharides (CPS) were characterized, and proved to play an important role in immune evasion and in other consequences of the infection. This is an innovative finding in fish bacteriology and resembles what, in other fields, has become apparent in the recent years: S. iniae alters surface antigens. By so doing, the pathogen escapes immune destruction. Immunological assays (agar-gel immunodiffusion and antibody titers) confirmed that only limited cross recognition between the two types occurs and that capsular polysaccharides are immunodominant. Vaccination with purified CPS (as an acellular vaccine) results in protection. In vitro and ex-vivo models have allowed us to unravel additional insights of the host-pathogen interactions. S. iniae 173 (type II) produced DNA fragmentation of TMB-8 cells characteristic of cellular necrosis; the same isolate also prevented the development of apoptosis in NCC. This was determined by finding reduced expression of phosphotidylserine (PS) on the outer membrane leaflet of NCC. NCC treated with this isolate had very high levels of cellular necrosis compared to all other isolates. This cellular pathology was confirmed by observing reduced DNA laddering in these same treated cells. Transmission EM also showed characteristic necrotic cellular changes in treated cells. To determine if the (in vitro) PCD/apoptosis protective effects of #173 correlated with any in vivo activity, tilapia were injected IV with #173 and #164 (an Israeli type I strain). Following injection, purified NCC were tested (in vitro) for cytotoxicity against HL-60 target cells. Four significant observations were made : (i) fish injected with #173 had 100-400% increased cytotoxicity compared to #164 (ii) in vivo activation occurred within 5 minutes of injection; (iii) activation occurred only within the peripheral blood compartment; and (iv) the isolate that protected NCC from apoptosis in vitro caused in vivo activation of cytotoxicity. The levels of in vivo cytotoxicity responses are associated with certain pathogens (pathogen associated molecular patterns/PAMP) and with the tissue of origin of NCC. NCC from different tissue (i.e. PBL, anterior kidney, spleen) exist in different states of differentiation. Random amplified polymorphic DNA (RAPD) analysis revealed the "adaptation" of the bacterium to the vaccinated environment, suggesting a "Darwinian-like" evolution of any bacterium. Due to the selective pressure which has occurred in the vaccinated environment, type II strains, able to evade the protective response elicited by the vaccine, have evolved from type I strains. The increased virulence through the appropriation of a novel antigenic composition conforms with pathogenic mechanisms described for other streptococci. Vaccine efficacy was improved: water-in-oil formulations were found effective in inducing protection that lasted for a period of (at least) 6 months. Protection was evaluated by functional tests - the protective effect, and immunological parameters - elicitation of T- and B-cells proliferation. Vaccinated fish were found to be resistant to the disease for (at least) six months; protection was accompanied by activation of the cellular and the humoral branches.
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