Gotowa bibliografia na temat „Cell coculture”
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Artykuły w czasopismach na temat "Cell coculture"
Miyoshi, Hirotoshi, Chiaki Sato, Yuichiro Shimizu i Misa Morita. "Expansion of mouse hematopoietic stem/progenitor cells in three-dimensional cocultures on growth-suppressed stromal cell layer". International Journal of Artificial Organs 42, nr 7 (12.02.2019): 374–79. http://dx.doi.org/10.1177/0391398819827596.
Pełny tekst źródłaHirschi, Karen K., Stephanie A. Rohovsky i Patricia A. D'Amore. "PDGF, TGF-β, and Heterotypic Cell–Cell Interactions Mediate Endothelial Cell–induced Recruitment of 10T1/2 Cells and Their Differentiation to a Smooth Muscle Fate". Journal of Cell Biology 141, nr 3 (4.05.1998): 805–14. http://dx.doi.org/10.1083/jcb.141.3.805.
Pełny tekst źródłaGilead, L., O. Bibi i E. Razin. "Fibroblasts induce heparin synthesis in chondroitin sulfate E containing human bone marrow-derived mast cells". Blood 76, nr 6 (15.09.1990): 1188–95. http://dx.doi.org/10.1182/blood.v76.6.1188.1188.
Pełny tekst źródłaGilead, L., O. Bibi i E. Razin. "Fibroblasts induce heparin synthesis in chondroitin sulfate E containing human bone marrow-derived mast cells". Blood 76, nr 6 (15.09.1990): 1188–95. http://dx.doi.org/10.1182/blood.v76.6.1188.bloodjournal7661188.
Pełny tekst źródłaPortnoy, Joshua, Tianli Pan, Charles A. Dinarello, John M. Shannon, Jay Y. Westcott, Lening Zhang i Robert J. Mason. "Alveolar type II cells inhibit fibroblast proliferation: role of IL-1α". American Journal of Physiology-Lung Cellular and Molecular Physiology 290, nr 2 (luty 2006): L307—L316. http://dx.doi.org/10.1152/ajplung.00102.2005.
Pełny tekst źródłaHyakumura, Tomoko, Stuart McDougall, Sue Finch, Karina Needham, Mirella Dottori i Bryony A. Nayagam. "Organotypic Cocultures of Human Pluripotent Stem Cell Derived-Neurons with Mammalian Inner Ear Hair Cells and Cochlear Nucleus Slices". Stem Cells International 2019 (20.11.2019): 1–14. http://dx.doi.org/10.1155/2019/8419493.
Pełny tekst źródłaZotova, Anastasia, Anastasia Atemasova, Alexey Pichugin, Alexander Filatov i Dmitriy Mazurov. "Distinct Requirements for HIV-1 Accessory Proteins during Cell Coculture and Cell-Free Infection". Viruses 11, nr 5 (26.04.2019): 390. http://dx.doi.org/10.3390/v11050390.
Pełny tekst źródłaWang, Qishan, Bingxin Xu, Kaijian Fan, Jing Wu i Tingyu Wang. "CypB-CD147 Signaling Is Involved in Crosstalk between Cartilage and FLS in Collagen-Induced Arthritis". Mediators of Inflammation 2020 (29.08.2020): 1–12. http://dx.doi.org/10.1155/2020/6473858.
Pełny tekst źródłaLoibl, Markus, Andreas Binder, Marietta Herrmann, Fabian Duttenhoefer, R. Geoff Richards, Michael Nerlich, Mauro Alini i Sophie Verrier. "Direct Cell-Cell Contact between Mesenchymal Stem Cells and Endothelial Progenitor Cells Induces a Pericyte-Like Phenotype In Vitro". BioMed Research International 2014 (2014): 1–10. http://dx.doi.org/10.1155/2014/395781.
Pełny tekst źródłaBurger, Jan A., Maite P. Quiroga, Elena Hartmann, Andrea Bürkle, William G. Wierda, Michael J. Keating i Andreas Rosenwald. "High-level expression of the T-cell chemokines CCL3 and CCL4 by chronic lymphocytic leukemia B cells in nurselike cell cocultures and after BCR stimulation". Blood 113, nr 13 (26.03.2009): 3050–58. http://dx.doi.org/10.1182/blood-2008-07-170415.
Pełny tekst źródłaRozprawy doktorskie na temat "Cell coculture"
Apple, Allon Aliza. "Bilaminar coculture of stem cells and instructive cells for tissue regeneration". Diss., Search in ProQuest Dissertations & Theses. UC Only, 2009. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3390115.
Pełny tekst źródłaSource: Dissertation Abstracts International, Volume: 71-02, Section: B, page: . Adviser: Jeffrey C. Lotz.
Hakelius, Malin. "Interactions between Malignant Keratinocytes and Fibroblasts : Studies in Head and Neck Squamous Cell Carcinoma". Doctoral thesis, Uppsala universitet, Plastikkirurgi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-221109.
Pełny tekst źródłaChamayou, Léo. "LiverPearls, une méthode de culture multicellulaire miniaturisée et à haut débit reproduisant l’environnement physiologique et la structure tridimensionnelle du foie humain". Thesis, Université Paris sciences et lettres, 2020. http://www.theses.fr/2020UPSLS005.
Pełny tekst źródłaInterest for new and more physiologically relevant liver models is high, particularly from pharmaceutical companies. Standard systems, like 2D culture, are indeed not enough predictive and better models are needed, either for drug candidates screening in ADME/Tox studies or for hepatic diseases modelling. To be closer to the human liver, a new model needs toreplicate liver structure and cellular composition better than the 2D. To this end, we used a micro-encapsulation technology, developed by the laboratory and based on the co-extrusion of a two-phases jet, composed of an alginate external phase and a cell-containing internal phase. This jet is then fragmented into micro-droplets and the alginate reticulated to form core-shell microcapsules. The porous alginate shell protects the cells from shear stress while letting oxygen and nutrients pass, and by preventing cell adhesion, enables the cells to self-assemble into hepatic spheroids which can bekept alive during one month, retain good functionality and can be used for high-throughput screening. This thesis focusedon using this technology to develop a next 3D liver model containing human primary hepatocytes, Kupffer cells and liver sinusoidal endothelial cells. Firstly, culture conditions for this model had to be optimized, particularly the ratio between these different cell types and the culture medium, which had to be suitable for these cell types. Then, once the culture conditions had been established, the model was characterized, structurally by immunofluorescence staining, and functionally by studying gene expression of important liver proteins, like cytochromes P450 or nuclear receptors. Enzymaticactivity, albumin and urea secretion were also studied. These capsules allow us to obtain a model able to replicate the complex interactions between these cell types and structurally closer to the human liver
Messelmani, Taha. "Development and characterisation of a biomimetic liver on chip featuring 3D hepatic coculture with an endothelial barrier". Electronic Thesis or Diss., Compiègne, 2023. http://www.theses.fr/2023COMP2736.
Pełny tekst źródłaDuring drugs development programs, animal models are commonly used for the assessment of the metabolism and toxicity of drug candidates. Several legal frameworks are being settled to promote the replacement, the reduction, and the refinement of these experiments. The liver is a central organ involved in the detoxification of exogenous molecules. Accordingly, the development of models mimicking the functions of the liver remain a challenging objective. Conventionally, liver cells are cultured in vitro in 2D Petri dishes but this conformation leads to a rapid loss of their functions. In recent years, the association between tissue engineering and organ-on-chip technology led to the development of more accurate alternative models that mimic the liver functions. The aim of this thesis is to develop a biomimetic liver-on-chip platform by coupling a hepatocyte biochip and an endothelial-like barrier. The goal is to mimic the passage of molecules through the liver sinusoid endothelial barrier and then their metabolism with the hepatocytes. In the first part, we used organ-on-chip technology and ECM-based hydroscaffold to organise the cells in 3D structures. The potential of our model was compared with static Petri dishes and the spheroids formed were characterised structurally and functionally. In the second part, we characterized the formation of an endothelial barrier and identified specific markers indicating the conservation of the phenotype of endothelial cells. We established the coculture conditions and analysed the potential of coupling the endothelial barrier with the hepatocyte-on-chip to metabolize the APAP as a candidate molecule. Finally, we analysed the metabolomic signature of each condition, crosstalk between the cells, and identified the metabolic signature of APAP injury and described the reactions happening at metabolic level. In the last part, we proposed tracks of improvement by using primary hepatocytes or by integrating the endothelial barrier and the hepatocytes in the same bi-compartmentalized biochip
Kalman, Benoît. "Génération et optimisation de microtissus musculaires 3D in vitro". Thesis, Université Grenoble Alpes (ComUE), 2016. http://www.theses.fr/2016GREAI053.
Pełny tekst źródłaSkeletal muscle tissue engineering aims to build functional and physiological tissues in vitro in order to better understand myogenesis, to investigate the impact of genetic mutations and to screen potential therapies. Over the past few years, bi- and tridimensional models of muscle tissue have been developed, but most of these models are based on the use of murine cells and require large amounts of cells, thus limiting their relevance to study pathologies of human muscles and drug screening assays. Here we aimed at developing different models of human muscle microtissues to address these issues. By using microfabrication techniques, we first engineered a microgrooved platform we used to generate aligned multilayered skeletal muscle tissues from murine C2C12 myoblasts and human immortalized myoblasts. We showed the impact of topography and cell density on the maturation and myotube alignment. We then fabricated a microdevice, consisting of microwells containing two micropillars allowing an easy access to the contractility of muscle tissues. We engineered microtissues from C2C12 and C2C12 myoblasts electroporated with a mutated gene of desmin, and showed some limitation of this technique of transduction. Finally, we generated microtissues from human myoblasts. We investigated the role of the extracellular matrix in the tissue formation and evidenced the benefits of coculturing myoblasts and fibroblasts on the stability of muscle microtissues. Furthermore, we optimized the geometry of the micropillars to engineer and compare microtissues composed of human myoblasts isolated from healthy and diseased (Duchenne muscular dystrophy) patients. A proof of concept of the potential of this technology for screening chemical and gene therapies was established. We were indeed able to analyze in real time the effects of the Rho-associated kinase-inhibitor Y-27632 on the tissue contractility, as well as the transduction of a model fluorescent reporter gene. Altogether, the results of this work demonstrate the potential of this technology to study fundamental muscle biology, examine functional effects of patient-specific mutations or screen chemical and gene therapies
Joshi, Ramila Joshi. "Micro-engineering of embryonic stem cells niche to regulate neural cell differentiation". University of Akron / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=akron1544029342969082.
Pełny tekst źródłaMadiedo-Podvršan, Sabrina. "Development of a lung-liver in vitro coculture model for the risk assessment of inhaled xenobiotics". Electronic Thesis or Diss., Compiègne, 2022. http://www.theses.fr/2022COMP2703.
Pełny tekst źródłaUrbanization and globalization are prevailing social phenomena that multiply and complexify the sources of modern pollution. Amongst others, air pollution has been recognized as an omnipresent life-threatening hazard, comprising a wide range of toxic airborne xenobiotics that expose man to acute and chronic threats. The defense mechanisms involved in hazardous exposure responses are complex and comprise local and systemic biological pathways. Due to this complexity, animal models are considered prime study models. However, in light of animal experimentation reduction (3Rs), we developed and investigated an alternative in vitro method to study systemic-like responses to inhalationlike exposures. In this context, a coculture platform was established to emulate interorgan crosstalks between the pulmonary barrier, which constitutes the route of entry of inhaled compounds, and the liver, which plays a major role in xenobiotic metabolism. Both compartments respectively comprised a Calu-3 insert and a HepG2/C3A biochip which were jointly cultured in a dynamically-stimulated environment for 72 hours. The present model was characterized using acetaminophen (APAP), a well-documented hepatotoxicant, to visibly assess the passage and circulation of a xenobiotic through the device. Two kinds of models were developed: (1) the developmental model allowed for the technical setup of the coculture, and (2) the physiological-like model better approximates a vivo environment. Based on viability, and functionality parameters the developmental model showed that the Calu-3 bronchial barrier and the HepG2/C3A biochip can successfully be maintained viable and function in a dynamic coculture setting for 3 days. In a stress-induced environment, present results reported that the coculture model emulated active and functional in vitro crosstalk that seemingly was responsive to high (1.5 and 3 mM) and low (12 and 24 μM) xenobiotic exposure doses. Lung/liver crosstalk induced modulation of stress response dynamics, delaying cytotoxicity, proving that APAP fate, biological behaviors and cellular stress responses were modulated in a broader systemic-like environment
Kletting, Stephanie [Verfasser], i Claus-Michael [Akademischer Betreuer] Lehr. "A new cell line-based coculture model of the human air-blood barrier to evaluate the interaction with aerosolized drug carriers / Stephanie Kletting ; Betreuer: Claus-Michael Lehr". Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2016. http://d-nb.info/1114735035/34.
Pełny tekst źródłaForte, Andresa. "Expansão ex vivo das células-tronco hematopoiéticas do sangue do cordão umbilical: análise comparativa da proliferação celular em cocultura de células-troco mesenquimais provenientes do endotélio vascular do cordão umbilical e do tecido adiposo". Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/5/5167/tde-25022015-085731/.
Pełny tekst źródłaINTRODUCTION: Umbilical cord blood (UCB) hematopoietic stem cells have been successfully used for the treatment of both malignant and non-malignant diseases. Nevertheless, some UCB units could have low total nucleated cells (TNC) dose. Several approaches have been suggested to avoid inadequacy problems of hematopoietic stem cells (HSC) number for transplantation, such as administration of two UCB units to the patient and HSC ex vivo expansion. OBJECTIVE: Evaluate UCB ex vivo expansion proliferative rates in a high and low mesenchymal stem cells (MSC) confluence feeder layer obtained from different MSC sources and by adding or not cytokines cocktail into the medium. METHODS: This study was approved by the Research Ethic Committee (CAPPESQ) of Hospital das Clínicas da Faculdade de Medicina da USP. The collection of UCB (n=10) was made after delivery of the infant and the expulsion of placenta. Processing was performed using volume reduction method which consists in red blood depletion. MSC samples from umbilical cord endothelium were obtained from three different donors and adipose tissue (n=3) obtained from LIM31\'s pattern inventory. The total nucleated cell (TNC), expression of hematopoietic surface markers such as CD133+/CD34+ were observed after seven days of culture. Beyond that, colony forming unit assay (CFU) was performed before and after UCB expansion. The expansion by coculture method was observed in two groups (Group I - coculture with cytokines cocktail added vs. Group II- coculture without cytokines cocktail) for both MSCs sources. RESULTS: After seven days, analysis of confluent coculture showed that TNC proliferation rate ware almost 2 times higher than in subconfluent coculture (35 vs. 16-fold) in Group I and also revealed higher proliferative rate in CD133+/CD34+ cells considering. CFU showed similar increase after seven days of culture in comparison of day 0 (up to 8-fold). Subconfluent coculture for both umbilical cord endothelium and adipose tissue showed lower yield compared with those with high MSC confluence. The expansion in the presence of cytokines showed higher cell proliferation compared to the cocultures without addition of cytokines. CONCLUSION: This study showed that coculture system may require the addition of cytokines cocktail in the media and confluent MSC regardless of source for high yield of UCB cells
Castro, Mike. "Cytokine Modulation of Cardiomyocyte-Macrophage Interaction". Wright State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=wright157858331333014.
Pełny tekst źródłaCzęści książek na temat "Cell coculture"
Afshari, Fardad T., i James W. Fawcett. "Astrocyte–Schwann-Cell Coculture Systems". W Methods in Molecular Biology, 381–91. Totowa, NJ: Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-452-0_25.
Pełny tekst źródłaDavies, P. F. "Coculture of Endothelial and Smooth Muscle Cells". W Cell Culture Techniques in Heart and Vessel Research, 290–98. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-75262-9_19.
Pełny tekst źródłaPiersma, A. H., A. Willemse, C. E. van den Brink, S. W. de Laat i C. L. Mummery. "Mesodermal Differentiation of Embryonal Carcinoma Cells in Coculture with Visceral Endoderm Cell Lines". W Cell to Cell Signals in Mammalian Development, 247–60. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-73142-6_20.
Pełny tekst źródłaThanabalasundaram, Gokulan, Jehad El-Gindi, Mira Lischper i Hans-Joachim Galla. "Methods to Assess Pericyte-Endothelial Cell Interactions in a Coculture Model". W Methods in Molecular Biology, 379–99. Totowa, NJ: Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-938-3_19.
Pełny tekst źródłaKatyshev, Vladimir, i Paula Dore-Duffy. "Pericyte Coculture Models to Study Astrocyte, Pericyte, and Endothelial Cell Interactions". W Methods in Molecular Biology, 467–81. Totowa, NJ: Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-452-0_31.
Pełny tekst źródłaSatsu, Hideo, i Makoto Shimizu. "Food factors that regulate intestinal inflammation: evaluation of the factors by using a coculture system". W Animal Cell Technology: Basic & Applied Aspects, 29–37. Dordrecht: Springer Netherlands, 2006. http://dx.doi.org/10.1007/1-4020-4457-7_4.
Pełny tekst źródłaSwearingen, Michelle, Beverly Falcon, Sudhakar Chintharlapalli i Mark Uhlik. "An Endothelial Cell/Mesenchymal Stem Cell Coculture Cord Formation Assay to Model Vascular Biology In Vitro". W Methods in Molecular Biology, 371–82. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7357-6_21.
Pełny tekst źródłaTakami, Masamichi, Je-Tae Woo i Kazuo Nagai. "Increase of Intracellular Ca2+ Level Induces Osteoclast- Like Cell Formation in Coculture of Mouse Bone Marrow Cells and Osteoblastic Cells". W Animal Cell Technology: Basic & Applied Aspects, 97–101. Dordrecht: Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-5161-0_17.
Pełny tekst źródłaTorres-Barrera, Patricia, Mireya Ramírez-Florencio i Antonieta Chávez-González. "Assessment of Cell Cycle in Primitive Chronic Myeloid Leukemia Cells by Flow Cytometry After Coculture with Endothelial Cells". W Methods in Molecular Biology, 207–16. New York, NY: Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0759-6_13.
Pełny tekst źródłaBabetto, Elisabetta. "A Schwann Cell–Neuron Coculture System to Study Neuron–Glia Interaction During Axon Degeneration". W Methods in Molecular Biology, 97–110. New York, NY: Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0585-1_8.
Pełny tekst źródłaStreszczenia konferencji na temat "Cell coculture"
Lee, Jyong-Huei, Yi-Ting Lo i Shih-Kang Fan. "Cell coculture within electrically patterned cells and hydrogel structures". W 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems (MEMS). IEEE, 2017. http://dx.doi.org/10.1109/memsys.2017.7863478.
Pełny tekst źródłaScott, Devon, Aaron Richman, Craig Lanning, Robin Shandas i Wei Tan. "Devlopment of a Cell Coculture Microfluidic Shear Device for Mechano-Transmission Study". W ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176700.
Pełny tekst źródłaHolle, Andrew W., Verena Kast, Ralf Kemkemer i Joachim Spatz. "Abstract 5059: Cancer cell invasion dynamics in microchannels during stromal cell coculture". W Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-5059.
Pełny tekst źródłaPullens, Rolf A. A., Maria Stekelenburg, Carlijn V. C. Bouten, Frank P. T. Baaijens i Mark J. Post. "3D Coculture of Human Endothelial Cells and Myofibroblasts for Vascular Tissue Engineering". W ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176099.
Pełny tekst źródłaAlcolea, Marla, Renata Moraes Brito, Mahmi Fujimori, Adenilda Cristina Honorio-França, Eduardo Luzia França i Paula Becker Pertuzatti. "IMMUNOMODULATORY EFFECTS OF HONEY FROM STINGLESS BEES AND HONEY BEES ON BREAST CANCER CELLS". W Brazilian Breast Cancer Symposium 2022. Mastology, 2022. http://dx.doi.org/10.29289/259453942022v32s2002.
Pełny tekst źródłaTrehan, Kartik, Christopher Yu, Sasha Bakhru i Hai-Quan Mao. "Novel Hydrogel Microfibers for Tissue Engineering". W ASME 2007 2nd Frontiers in Biomedical Devices Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/biomed2007-38066.
Pełny tekst źródłaAnselmino, Nicolás, Alejandra Páez, Sofía Lage Vickers, Javier Cotignola, Pía Valacco, Geraldine Gueron i Elba Vázquez. "Abstract B062: Proteomic characterization of the secretome from prostate cancer and bone progenitor cell coculture". W Abstracts: AACR Special Conference: Prostate Cancer: Advances in Basic, Translational, and Clinical Research; December 2-5, 2017; Orlando, Florida. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.prca2017-b062.
Pełny tekst źródłaShammout, B., i J. Johnson. "Modelling Fibrosis via Three Dimensional Pericyte-Endothelial Cell Coculture Using Biocompatible Nanoparticle Assembly and Spheroid Bioprinting Identifies Novel Therapeutic Targets". W American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4061.
Pełny tekst źródłaAgulló-Ortuño, Mª Teresa, Elena Prieto-García, C. Vanesa Díaz-García, Irene Otero Blas, Inmaculada García-Ruíz i José A. López-Martín. "Abstract 5893: Bioenergetic signature from cocultures of pancreatic tumor cell lines and fibroblasts". W Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-5893.
Pełny tekst źródłaDaszkiewicz, Lidia, Gera Goverse, Nataliia Beztsinna, Benjamin Visser, Lois van der Drift, Kuan Yan i Leo Price. "Abstract 4543: Phenotypic screening of bispecific antibodies in 3D tumor immune cell cocultures". W Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-4543.
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