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Artykuły w czasopismach na temat „Carotid Arterial Pulse Pressure Waveform (CAPPW)”

Autor: Grafiati

Data publikacji: 6 września 2023

Data aktualizacji: 31 lipca 2025

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1

Liu, Chengyu, Tao Zhuang, Lina Zhao, et al. "Modelling Arterial Pressure Waveforms Using Gaussian Functions and Two-Stage Particle Swarm Optimizer." BioMed Research International 2014 (2014): 1–10. http://dx.doi.org/10.1155/2014/923260.

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Changes of arterial pressure waveform characteristics have been accepted as risk indicators of cardiovascular diseases. Waveform modelling using Gaussian functions has been used to decompose arterial pressure pulses into different numbers of subwaves and hence quantify waveform characteristics. However, the fitting accuracy and computation efficiency of current modelling approaches need to be improved. This study aimed to develop a novel two-stage particle swarm optimizer (TSPSO) to determine optimal parameters of Gaussian functions. The evaluation was performed on carotid and radial artery pr

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Salvi, Paolo, Filippo Valbusa, Anna Kearney-Schwartz, et al. "Non-Invasive Assessment of Arterial Stiffness: Pulse Wave Velocity, Pulse Wave Analysis and Carotid Cross-Sectional Distensibility: Comparison between Methods." Journal of Clinical Medicine 11, no. 8 (2022): 2225. http://dx.doi.org/10.3390/jcm11082225.

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Background: The stiffening of large elastic arteries is currently estimated in research and clinical practice by propagative and non-propagative models, as well as parameters derived from aortic pulse waveform analysis. Methods: Common carotid compliance and distensibility were measured by simultaneously recording the diameter and pressure changes during the cardiac cycle. The aortic and upper arm arterial distensibility was estimated by measuring carotid–femoral and carotid–radial pulse wave velocity (PWV), respectively. The augmentation index and blood pressure amplification were derived fro

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van Houwelingen, Marc J., Daphne Merkus, Jan Hofland, et al. "A novel approach to assess hemorrhagic shock severity using the arterially determined left ventricular isovolumic contraction period." American Journal of Physiology-Heart and Circulatory Physiology 305, no. 12 (2013): H1790—H1797. http://dx.doi.org/10.1152/ajpheart.00504.2013.

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Recently, the ventilatory variation in pre-ejection period (ΔPEP) was found to be useful in the prediction of fluid-responsiveness of patients in shock. In the present study we investigated the behavior of the ventilation-induced variations in the systolic timing intervals in response to a graded hemorrhage protocol. The timing intervals studied included the ventilatory variation in ventricular electromechanical delay (ΔEMD), isovolumic contraction period (determined from the arterial pressure waveform, ΔAIC), pulse travel time (ΔPTT), and ΔPEP. ΔAIC and ΔPEP were evaluated in the aorta and ca

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Shibata, Shigeki, and Benjamin D. Levine. "Biological aortic age derived from the arterial pressure waveform." Journal of Applied Physiology 110, no. 4 (2011): 981–87. http://dx.doi.org/10.1152/japplphysiol.01261.2010.

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Indexes for arterial stiffness are, by their nature, influenced by the ambient blood pressure due to the curvilinear nature of arterial compliance. We developed a new concept of the “Modelflow aortic age,” which is, theoretically, not influenced by the ambient blood pressure and provides an easily understood context (biological vs. chronological age) for measures of arterial stiffness. The purpose of the present study was to validate this pressure-independent index for aortic stiffness in humans. Twelve sedentary elderly (65–77 yr), 11 Masters athletes (65–73 yr), and 12 sedentary young indivi

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Edwards, David G., Matthew S. Roy, and Raju Y. Prasad. "Wave reflection augments central systolic and pulse pressures during facial cooling." American Journal of Physiology-Heart and Circulatory Physiology 294, no. 6 (2008): H2535—H2539. http://dx.doi.org/10.1152/ajpheart.01369.2007.

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Cardiovascular events are more common in the winter months, possibly because of hemodynamic alterations in response to cold exposure. The purpose of this study was to determine the effect of acute facial cooling on central aortic pressure, arterial stiffness, and wave reflection. Twelve healthy subjects (age 23 ± 3 yr; 6 men, 6 women) underwent supine measurements of carotid-femoral pulse wave velocity (PWV), brachial artery blood pressure, and central aortic pressure (via the synthesis of a central aortic pressure waveform by radial artery applanation tonometry and generalized transfer functi

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Holewijn, Suzanne, Jenske J. M. Vermeulen, Majorie van Helvert, Lennart van de Velde, and Michel M. P. J. Reijnen. "Changes in Noninvasive Arterial Stiffness and Central Blood Pressure After Endovascular Abdominal Aneurysm Repair." Journal of Endovascular Therapy 28, no. 3 (2021): 434–41. http://dx.doi.org/10.1177/15266028211007460.

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Purpose: To evaluate the impact of elective endovascular aneurysm repair (EVAR) on the carotid-femoral pulse wave velocity (cfPWV) and central pressure waveform, through 1-year follow-up. Materials and Methods: A tonometric device was used to measure cfPWV and estimate the central pressure waveform in 20 patients with an infrarenal abdominal aortic aneurysm scheduled for elective EVAR. The evaluated central hemodynamic parameters included the central pressures, the augmentation index (AIx), and the subendocardial viability ratio (SEVR). AIx quantifies the contribution of reflected wave to the

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Reesink, Koen D., Evelien Hermeling, M. Christianne Hoeberigs, Robert S. Reneman, and Arnold P. G. Hoeks. "Carotid artery pulse wave time characteristics to quantify ventriculoarterial responses to orthostatic challenge." Journal of Applied Physiology 102, no. 6 (2007): 2128–34. http://dx.doi.org/10.1152/japplphysiol.01206.2006.

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Central blood pressure waveforms contain specific features related to cardiac and arterial function. We investigated posture-related changes in ventriculoarterial hemodynamics by means of carotid artery (CA) pulse wave analysis. ECG, brachial cuff pressure, and common CA diameter waveforms (by M-mode ultrasound) were obtained in 21 healthy volunteers (19–30 yr of age, 10 men and 11 women) in supine and sitting positions. Pulse wave analysis was based on a timing extraction algorithm that automatically detects acceleration maxima in the second derivative of the CA pulse waveform. The algorithm

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8

Yildiz, Mustafa. "Arterial Distensibility in Chronic Inflammatory Rheumatic Disorders." Open Cardiovascular Medicine Journal 4, no. 1 (2010): 83–88. http://dx.doi.org/10.2174/1874192401004010083.

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The pulse wave velocity (PWV), as an indicator of arterial distensibility, may play an important role in the stratification of patients based on the cardiovascular risk. PWV inversely correlates with arterial distensibility and relative arterial compliance. Decreased arterial distensibility alters arterial blood pressure and flow dynamics, and disturbes coronary perfusion. Systemic immune and inflammatory diseases, such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are associated with increased morbidity and mortality, predominantly due to adverse cardiovascular events. S

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9

Paré, Mathilde, Rémi Goupil, Catherine Fortier, et al. "Increased Excess Pressure After Creation of an Arteriovenous Fistula in End-Stage Renal Disease." American Journal of Hypertension 35, no. 2 (2021): 149–55. http://dx.doi.org/10.1093/ajh/hpab161.

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ABSTRACT BACKGROUND Reservoir-wave analysis (RWA) separates the arterial waveform into reservoir and excess pressure (XSP) components, where XSP is analogous to flow and related to left ventricular workload. RWA provides more detailed information about the arterial tree than traditional blood pressure (BP) parameters. In end-stage renal disease (ESRD), we have previously shown that XSP is associated with increased mortality and is higher in patients with arteriovenous fistula (AVF). In this study, we examined whether XSP increases after creation of an AVF in ESRD. METHODS Before and after a me

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10

Bentley, Gisele J., James R. Cox, Catherine Liao, Alberto Avolio, Ahmad Qasem, and Mark Butlin. "P182 AORTIC VASCULAR BIOMARKERS FOR THE EARLY DETECTION OF PLACENTAL SYNDROMES DURING PREGNANCY: A SYSTEMATIC REVIEW AND META-ANALYSIS." Journal of Hypertension 42, Suppl 3 (2024): e129. http://dx.doi.org/10.1097/01.hjh.0001063600.27122.5e.

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Background: Placental syndromes (PS) cause over 14 million complications and the death of more than 350,000 women each year. Women with preeclampsia (PE) or gestational hypertension (GH) typically exhibit late gestational acute brachial hypertension, making early intervention difficult. Non-invasive aortic waveform assessments provide nuanced insight to global cardiovascular function. Our objective is to delineate cardiovascular differences between complicated and normotensive pregnancies (NP), to identify early vascular markers of at-risk women. Methods: A systematic search (March 2024) for s

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Tomasova, Lenka, Marian Grman, Anton Misak, Lucia Kurakova, Elena Ondriasova, and Karol Ondrias. "Cardiovascular “Patterns” of H2S and SSNO−-Mix Evaluated from 35 Rat Hemodynamic Parameters." Biomolecules 11, no. 2 (2021): 293. http://dx.doi.org/10.3390/biom11020293.

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This work is based on the hypothesis that it is possible to characterize the cardiovascular system just from the detailed shape of the arterial pulse waveform (APW). Since H2S, NO donor S-nitrosoglutathione (GSNO) and their H2S/GSNO products (SSNO−-mix) have numerous biological actions, we aimed to compare their effects on APW and to find characteristic “patterns” of their actions. The right jugular vein of anesthetized rats was cannulated for i.v. administration of the compounds. The left carotid artery was cannulated to detect APW. From APW, 35 hemodynamic parameters (HPs) were evaluated. H2

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Balis, Peter, Andrea Berenyiova, Anton Misak, et al. "The Phthalic Selenoanhydride Decreases Rat Blood Pressure and Tension of Isolated Mesenteric, Femoral and Renal Arteries." Molecules 28, no. 12 (2023): 4826. http://dx.doi.org/10.3390/molecules28124826.

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Phthalic selenoanhydride (R-Se) solved in physiological buffer releases various reactive selenium species including H2Se. It is a potential compound for Se supplementation which exerts several biological effects, but its effect on the cardiovascular system is still unknown. Therefore, herein we aimed to study how R-Se affects rat hemodynamic parameters and vasoactive properties in isolated arteries. The right jugular vein of anesthetized Wistar male rats was cannulated for IV administration of R-Se. The arterial pulse waveform (APW) was detected by cannulation of the left carotid artery, enabl

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13

Misak, Anton, Lucia Kurakova, Andrea Berenyiova, et al. "Patterns and Direct/Indirect Signaling Pathways in Cardiovascular System in the Condition of Transient Increase of NO." BioMed Research International 2020 (May 28, 2020): 1–16. http://dx.doi.org/10.1155/2020/6578213.

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Aim. To study “patterns” and connections of signaling pathways derived from the rat arterial pulse waveform (APW) under the condition of transient NO increase. Methods and Results. The right jugular vein of anesthetized Wistar rats was cannulated for administration of NO donor S-nitrosoglutathione. The left carotid artery was cannulated to detect APW. From rat APW, 35 hemodynamic parameters (HPs) and several their crossrelationships were evaluated. We introduced a new methodology to study “patterns” and connections of different signaling pathways, which are suggested from hysteresis and nonhys

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Bartoloni, Elena, Giacomo Pucci, Francesca Cannarile, et al. "Central Hemodynamics and Arterial Stiffness in Systemic Sclerosis." October 18, 2016. https://doi.org/10.1161/hypertensionaha.116.08345.

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Although microvascular disease is a hallmark of systemic sclerosis (SSc), a higher prevalence of macrovascular disease and a poorer related prognosis have been reported in SSc than in the general population. The simultaneous assessment of prognostically relevant functional properties of larger and smaller arteries, and their effects on central hemodynamics, has never been performed in SSc using the state-of-the-art techniques. Thirty-four women with SSc (aged 61±15 years, disease duration 17±12 years, and blood pressure 123/70±18/11 mm Hg) and 34 healthy women individually matched by age and m

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Manoj, Rahul, Raj Kiran V, P. M. Nabeel, Mohanasankar Sivaprakasam, and Jayaraj Joseph. "Arterial pressure pulse wave separation analysis using a multi-gaussian decomposition model." Physiological Measurement, May 10, 2022. http://dx.doi.org/10.1088/1361-6579/ac6e56.

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Abstract Objective: Methods for separating the forward-backward components from blood pulse waves rely on simultaneously measured pressure and flow velocity from a target artery site. Modelling approaches for flow velocity simplify the wave separation analysis (WSA), providing a methodological and instrumentational advantage over the former; however, current methods are limited to the aortic site. In this work, a multi-Gaussian decomposition (MGD) modelled WSA (MGDWSA) is developed for a non-aortic site asuch as the carotid artery. While the model is an adaptation of the existing wave separati

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Ayer, Julian G., Albert Avolio, Guy Marks, Jason A. Harmer, and David S. Celermajer. "Abstract 2994: Gender-Related Differences in the Central Arterial Pressure Waveform Begin in Childhood and are Independent of Height." Circulation 118, suppl_18 (2008). http://dx.doi.org/10.1161/circ.118.suppl_18.s_802.

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Introduction Women develop age-related LV hypertrophy and symptomatic heart failure to a greater extent than men. Contributing to this may be a higher pulsatile afterload in women, with a higher central arterial systolic augmentation pressure (AP, peak pressure minus pressure at systolic shoulder) and augmentation index (AIx, ratio of AP to pulse pressure). It is unclear if these differences are due to gender per se or shorter female stature. We studied 8-year old children to determine if gender-related differences in carotid pressure augmentation are present in early life and if so, whether t

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Mitchell, Gary F., Jian Rong, Martin G. Larson, et al. "Vascular Age Assessed From an Uncalibrated, Noninvasive Pressure Waveform by Using a Deep Learning Approach: The AI-VascularAge Model." Hypertension, October 30, 2023. http://dx.doi.org/10.1161/hypertensionaha.123.21638.

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Background: Aortic stiffness, assessed as carotid-femoral pulse wave velocity, provides a measure of vascular age and risk for adverse cardiovascular disease outcomes, but it is difficult to measure. The shape of arterial pressure waveforms conveys information regarding aortic stiffness; however, the best methods to extract and interpret waveform features remain controversial. Methods: We trained a convolutional neural network with fixed-scale (time and amplitude) brachial, radial, and carotid tonometry waveforms as input and negative inverse carotid-femoral pulse wave velocity as label. Model

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Beeckman, Simeon, Smriti Badhwar, Yanlu Li, et al. "Heart-carotid pulse-wave velocity via laser-doppler vibrometry as a biomarker for arterial stiffening: a feasibility study." Physiological Measurement, April 10, 2025. https://doi.org/10.1088/1361-6579/adcb85.

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Abstract Objective: Large artery stiffening leads to an increase in cardiovascular risk and organ damage of the kidneys, brain or the heart. Biomarkers that allow for early detection of this phenomenon are a point of interest in research, with pulse-wave velocity (PWV) having been proven useful in predicting and monitoring arterial stiffness. We previously introduced a laser doppler vibrometry (LDV) prototype which can measure carotid-femoral PWV (cfPWV). In this work, we assesss the feasibility of using the same device to infer heart-carotid pulse-transit time (hcPTT) as a first step towards

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Sakuragi, Satoru, Richard D. Telford, and Walter P. Abhayaratna. "Abstract 4962: Influence of Adiposity on Carotid Wave Reflection and Arterial Stiffness: A Longitudinal Study in Healthy Children." Circulation 120, suppl_18 (2009). http://dx.doi.org/10.1161/circ.120.suppl_18.s1031.

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Background: The relationship between childhood obesity and adverse cardiovascular outcomes during adulthood may be mediated through the promotion of impaired vascular function. Wave reflection is an index of arterial function that is determined by arterial stiffness and is predictive of adverse cardiovascular events in adults. We hypothesized that baseline and changes in adiposity during childhood have an adverse influence on future levels of wave reflection and arterial stiffness. Methods: In 514 healthy children (mean age 8.3±0.4, 50% boys); percentage body fat (%BF) was quantitated by dual-

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Milkovich, Nicholas, Anastasia Gkousioudi, Francesca Seta, Béla Suki, and Yanhang Zhang. "Harmonic Distortion of Blood Pressure Waveform as a Measure of Arterial Stiffness." Frontiers in Bioengineering and Biotechnology 10 (March 30, 2022). http://dx.doi.org/10.3389/fbioe.2022.842754.

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Aging and disease alter the composition and elastic properties of the aortic wall resulting in shape changes in blood pressure waveform (BPW). Here, we propose a new index, harmonic distortion (HD), to characterize BPW and its relationship with other in vitro and in vivo measures. Using a Fourier transform of the BPW, HD is calculated as the ratio of energy above the fundamental frequency to that at the fundamental frequency. Male mice fed either a normal diet (ND) or a high fat, high sucrose (HFHS) diet for 2–10 months were used to study BPWs in diet-induced metabolic syndrome. BPWs were reco

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Hsu, Pai F., Shao Y. Chuang, Hao M. Cheng, et al. "Abstract 9349: Wave Reflection but Not Arterial Stiffness is Much Highly Correlated with Ambulatory Blood Pressure Parameters Including Blood Pressure Variability and Morning Blood Pressure Surge." Circulation 124, suppl_21 (2011). http://dx.doi.org/10.1161/circ.124.suppl_21.a9349.

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Background: With growing evidences that blood pressure (BP) variability, daily BP peak or morning BP surge are independently related to organ damage and future cardiovascular events. We try to invest the role of arterial stiffness and wave reflection, cardiac output in the association of those ambulatory BP parameters. Methods: A sample of 1156 normotensive and untreated hypertensive Taiwanese participants (546 women aged 30-79 years) was drawn from a community-based survey. All participants were recorded with 24 hours ambulatory blood pressure monitors. Besides, serum laboratory data, carotid

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Yavarimanesh, Mohammad, Hao-Min Cheng, Chen-Huan Chen, et al. "Abdominal aortic aneurysm monitoring via arterial waveform analysis: towards a convenient point-of-care device." npj Digital Medicine 5, no. 1 (2022). http://dx.doi.org/10.1038/s41746-022-00717-3.

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AbstractAbdominal aortic aneurysms (AAAs) are lethal but treatable yet substantially under-diagnosed and under-monitored. Hence, new AAA monitoring devices that are convenient in use and cost are needed. Our hypothesis is that analysis of arterial waveforms, which could be obtained with such a device, can provide information about AAA size. We aim to initially test this hypothesis via tonometric waveforms. We study noninvasive carotid and femoral blood pressure (BP) waveforms and reference image-based maximal aortic diameter measurements from 50 AAA patients as well as the two noninvasive BP w

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Sugawara, Jun, Tsubasa Tomoto, and Hirofumi Tanaka. "Comparisons of Proximal Aortic Pulse Wave Velocity Measurements: Carotid‐Femoral vs. Heart‐Brachial PWV." FASEB Journal 31, S1 (2017). http://dx.doi.org/10.1096/fasebj.31.1_supplement.1017.14.

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The proximal aorta (e.g., the ascending aorta and aortic arch) is the most elastic segment of the arterial tree directly connected with the left ventricle and plays the dominant role in buffering the cyclic mechanical forces of cardiac pulsations. Carotid‐femoral pulse wave velocity (cfPWV) is considered as the reference standard measurement for large elastic artery stiffness but the most proximal segments of the aorta are omitted in its measurement. The primary aim of the present study was to compare two indices of arterial stiffness that differ in the contribution of proximal aortic segments

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Shoemaker, Leena N., Tyson Matern, Farah Kamar, et al. "Blood pressure in human large cerebral arteries: A feasibility study." Journal of Applied Physiology, February 7, 2025. https://doi.org/10.1152/japplphysiol.00825.2024.

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Background: The lack of direct measures of brain blood pressure (BBP) has severely restricted understanding of cerebral pressure-flow relationships and their control. We sought to evaluate the feasibility of directly measuring BBP and its pulsatility between the aorta and middle cerebral artery (MCA) during elective endovascular surgical procedures. Methods: We report five case studies (four female, 61 ± 13 years; Mean ± SD) of patients undergoing cerebrovascular interventional procedures for aneurysm and stenoses using direct BBP measures with the COMET 2 pressure guidewire system (Boston Sci

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Niroumandi, Soha, Derek Rinderknecht, Coskun Bilgi, et al. "Abstract 18846: A Noninvasive Smartphone Assessment of Aortic Arch Pulse Wave Velocity and Total Arterial Compliance." Circulation 148, Suppl_1 (2023). http://dx.doi.org/10.1161/circ.148.suppl_1.18846.

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Introduction: Several clinical studies including a large multiethnic population (Dallas Heart Study) have shown that total arterial compliance (TAC) and aortic arch pulse wave velocity (PWV aa ) are predictors of cardiovascular disease (CVD) events. Dallas Heart Study also showed that PWV aa predicts brain white matter hyperintensity volume independent of cardiovascular risk factors. Recently, Intrinsic Frequency (IF) analysis of carotid pressure waveform from the Framingham Heart Study was used to predict heart failure (HF) events and CVD (Hypertension, 2021 PMID: 33390053). Aim: Our goal was

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Djuric, B., K. Zikic, N. Milosevic, Z. Nestorovic, and D. Zikic. "Aging related changes in cardiovascular system in healthy female population: photoplethysmography method and DFA analysis." Cardiovascular Research 120, Supplement_1 (2024). http://dx.doi.org/10.1093/cvr/cvae088.148.

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Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Ministry of Science Technological Development and Innovation Background The cardiovascular system undergoes dynamic changes during the biological aging in humans, leading to chronic cardiovascular and cerebrovascular diseases. Purpose Developing the novel method for non-invasive monitoring of age induced changes in arterial vessels. Methodology The pilot study was performed on 58 women, in good health, non-smokers, between the ages of 20 and 70, divided into three age grou

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Huang, Chieh-Chun, Shih-Hsien Sung, Wei-Ting Wang, et al. "Examining arterial pulsation to identify and risk-stratify heart failure subjects with deep neural network." Physical and Engineering Sciences in Medicine, February 15, 2024. http://dx.doi.org/10.1007/s13246-023-01378-6.

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AbstractHemodynamic parameters derived from pulse wave analysis have been shown to predict long-term outcomes in patients with heart failure (HF). Here we aimed to develop a deep-learning based algorithm that incorporates pressure waveforms for the identification and risk stratification of patients with HF. The first study, with a case–control study design to address data imbalance issue, included 431 subjects with HF exhibiting typical symptoms and 1545 control participants with no history of HF (non-HF). Carotid pressure waveforms were obtained from all the participants using applanation ton

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Aghilinejad, Arian, and Morteza Gharib. "Assessing Pressure Wave Components for Aortic Stiffness Monitoring through Spectral Regression Learning." European Heart Journal Open, May 21, 2024. http://dx.doi.org/10.1093/ehjopen/oeae040.

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Abstract Aims The aging process notably induces structural changes in the arterial system, primarily manifesting as increased aortic stiffness, a precursor to cardiovascular events. While wave separation analysis is a robust tool for decomposing the components of blood pressure waveform, its relationship with cardiovascular events, such as aortic stiffening, is incompletely understood. Furthermore, its applicability has been limited due to the need for concurrent measurements of pressure and flow. Our aim in this study addresses this gap by introducing a spectral regression learning method for

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Wang, Kang-Ling, Hao-Min Cheng, Shao-Yuan Chuang, et al. "Abstract 5151: Waveform Reflections and Arterial Stiffness in the Prediction of 15.1-Year All-Cause and Cardiovascular Mortalities: A Community-Based Study." Circulation 120, suppl_18 (2009). http://dx.doi.org/10.1161/circ.120.suppl_18.s1061-c.

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Background- The role of arterial wave reflection, usually assessed by the transit-time dependent augmentation index (AI) and augmented pressure (Pa), in the prediction of cardiovascular events may have been underestimated. We investigated whether the transit-time independent measurements of reflected wave magnitude predict cardiovascular outcomes independently of arterial stiffness indexed by carotid-femoral pulse wave velocity (PWV). Method- A total of 1272 participants (47.0% women) from a community-based survey were studied. Carotid pressure waveforms derived by tonometry were decomposed to

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Armstrong, Matthew K., Shivangi Jain, Virginia Nuckols, et al. "Abstract P230: Central Artery Pulsatile Hemodynamics Are Associated With Cerebral Total, Periventricular, And Deep White Matter Lesions: Role Of Reservoir-excess Pressure Components." Hypertension 80, Suppl_1 (2023). http://dx.doi.org/10.1161/hyp.80.suppl_1.p230.

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Introduction: Accumulating evidence suggests that increased central, rather than peripheral, blood pressure (BP) may be a better predictor of cardiovascular risk. The shape of the central BP waveform is determined by ventricular-arterial interactions that can be quantified via novel hemodynamic analyses, from which some parameters have been implicated in the development of cardiac, vascular, and renal dysfunction. Comparatively, the potential effect of central pulsatile hemodynamics on brain structure has been understudied. Thus, we sought to determine the association of novel central hemodyna

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Bia, Daniel, Yanina Zócalo, Ramiro Sánchez, et al. "Aortic systolic and pulse pressure invasively and non-invasively obtained: Comparative analysis of recording techniques, arterial sites of measurement, waveform analysis algorithms and calibration methods." Frontiers in Physiology 14 (January 16, 2023). http://dx.doi.org/10.3389/fphys.2023.1113972.

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Background: The non-invasive estimation of aortic systolic (aoSBP) and pulse pressure (aoPP) is achieved by a great variety of devices, which differ markedly in the: 1) principles of recording (applied technology), 2) arterial recording site, 3) model and mathematical analysis applied to signals, and/or 4) calibration scheme. The most reliable non-invasive procedure to obtain aoSBP and aoPP is not well established.Aim: To evaluate the agreement between aoSBP and aoPP values invasively and non-invasively obtained using different: 1) recording techniques (tonometry, oscilometry/plethysmography,

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Shibata, Shigeki, Naoki Fujimoto, Jeffrey L. Hastings, et al. "Abstract 18213: Advanced Glycation End-Product Inhibition With Alagebrium Slows Age-Related Large Vessel Arterial Stiffening in Healthy Elderly Humans." Circulation 128, suppl_22 (2013). http://dx.doi.org/10.1161/circ.128.suppl_22.a18213.

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Background: Lifelong exercise training maintains youthful compliance of the central arteries, while even prolonged (1 yr) and intense training started later in life failed to reverse age-related central arterial stiffening, possibly because of accumulation of irreversible advanced glycation end-products (AGE). Alagebrium breaks AGE crosslinks and improves central arterial compliance in animals. However, little is known how Alagebrium would affect central arterial compliance in previously sedentary elderly humans. Moreover, it is unclear whether a strategy of exercise training combined with Ala

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Singh, R. P., S. Tewari, A. Kapoor, et al. "P41 Correlation of doppler ultrasound assessment of carotid femoral pulse wave velocity with coronary artery disease." European Heart Journal 41, Supplement_1 (2020). http://dx.doi.org/10.1093/ehjci/ehz872.035.

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Abstract Funding Acknowledgements self Background Arterial stiffness is an important cardiovascular risk factor. Carotid femoral pulse wave velocity (cfPWV) is simple noninvasive method to determine aortic stiffness. Arterial stiffness measures, cfPWV in particular, have been found to be correlate with stroke and peripheral artery disease. Usually SphygmoCor or Complior are used to calculate cfPWV. Doppler ultrasound can serve as an alternative to these methods. Purpose To assess cfPWV using doppler ultrasound and study its correlation with coronary artery disease and its severity. Methods cfP

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Scheuermann, Britton, Shannon Parr, Stephen Hammond, Vanessa-Rose Turpin, Olivia Kunkel, and Carl Ade. "Age-related impacts of wave transmission at the aorta-carotid bifurcation on local and global measures of arterial stiffness." Physiology 38, S1 (2023). http://dx.doi.org/10.1152/physiol.2023.38.s1.5734426.

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Wave reflections in the periphery have been key in the understanding of aging-related changes in global arterial stiffness, as measured by carotid-femoral pulse-wave velocity (cfPWV). However, recent investigations have demonstrated benefits of using local measures of aortic arch PWV (aaPWV) in addition to considering cfPWV. The contribution of proximal wave reflections at the aorta-carotid bifurcation to aaPWV, as well as to the increasing discordance between aaPWV and cfPWV previously observed with aging, remain poorly understood. The purpose of the present investigation was to examine the i

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Hao, Zhili, MD Mahfuzur Rahman, Jason Au, Chloe Athaide, and Lauren Jutlah. "Axial Wall Displacement At the Common Carotid Artery is Associated with the Lamb Waves." Journal of Engineering and Science in Medical Diagnostics and Therapy, November 16, 2022, 1–40. http://dx.doi.org/10.1115/1.4056267.

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Abstract As compared with its radial wall displacement, axial wall displacement at the common carotid artery (CCA) carries independent clinical values, but its physical mechanisms are unclear. This study aims to investigate whether axial wall displacement at the CCA is solely from Young waves. A pulse wave propagation theory is utilized to identify two types of waves, Young waves and Lamb waves, in an artery, and identifies two sources for axial wall displacement, wall shear stress and radial wall displacement gradient with a factor of the difference between axial and circumferential initial t

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Heffernan, Kevin, Lee Stoner, Michelle L. Meyer, et al. "Associations between estimated and measured carotid-femoral pulse wave velocity in older Black and White adults: the atherosclerosis risk in communities (ARIC) study." Journal of Cardiovascular Aging, 2022. http://dx.doi.org/10.20517/jca.2021.22.

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Introduction: Aortic stiffness offers important insight into vascular aging and cardiovascular disease (CVD) risk. The referent measure of aortic stiffness is carotid-femoral pulse wave velocity (cfPWV). cfPWV can be estimated (ePWV) from age and mean arterial pressure. Few studies have directly compared the association of ePWV to measured cfPWV, particularly in non-White adults. Moreover, whether ePWV and cfPWV correlate similarly with CVD risk remains unexplored. Aim: (1) To estimate the strength of the agreement between ePWV and cfPWV in both Black and White older adults; and (2) to compare

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Bruno, R. M., N. Di Lascio, A. Al Hussaini, et al. "P2538Arterial stiffness and remodeling from large to small arteries in patients with spontaneous coronary artery dissection: evidence for a systemic subclinical involvement." European Heart Journal 40, Supplement_1 (2019). http://dx.doi.org/10.1093/eurheartj/ehz748.0866.

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Abstract Background and aim Spontaneous coronary artery dissection (SCAD) is a major cause of acute coronary syndrome in women aged 50 years or less (22–43%). Its etiology is still unknown, though an association with systemic diseases such as fibromuscular dysplasia and collagenopathies has been found. This study is aimed at investigating the presence of subclinical structural and functional alterations in extracoronary districts in SCAD patients. Methods The design was a case-control study. Carotid, radial and digital arteries were scanned by standard or ultrahigh frequency ultrasound; clips

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Heusinkveld, Maarten H. G., Robert J. Holtackers, Bouke P. Adriaans, et al. "Complementing sparse vascular imaging data by physiological adaptation rules." Journal of Applied Physiology, October 29, 2020. http://dx.doi.org/10.1152/japplphysiol.00250.2019.

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Introduction:Mathematical modeling of pressure and flow waveforms in blood vessels using pulse wave propagation (PWP)-models has tremendous potential to support clinical decision-making. For a personalized model outcome, measurements of all modeled vessel radii and wall thicknesses are required. In clinical practice, however, data sets are often incomplete. To overcome this problem, we hypothesized that the adaptive capacity of vessels in response to mechanical load could be utilized to fill in the gaps of incomplete patient-specific data sets. Methods:We implemented homeostatic feedback loops

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Calvez, Valentin, Marco Palladino, Giulio Montefusco, et al. "Abstract P517: Dialysis Vintage Longer Than Sixty Months Contributes to Increased Arterial Stiffness and Impaired Diastolic Function in Patients with End-stage Renal Disease." Hypertension 70, suppl_1 (2017). http://dx.doi.org/10.1161/hyp.70.suppl_1.p517.

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Hemodialysis (HD) may induce vascular stiffness through several mechanisms. We sought to determine the role of dialysis vintage (DV) on the development of cardiovascular alterations. We studied 14 patients in chronic HD and 24 newly diagnosed never treated hypertensive patients and 16 normotensive controls. The patients in HD were divided in two groups according to DV: <60-months (DV<60,n=7) or >60-months (DV>60,n=7). After HD session, when dry weight was reached, we evaluated peripheral blood pressure (pBP), the parameters derived by tonometric analysis of the pulse waveform (cent

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