Artykuły w czasopismach: „Cancer – Nutritional aspects”

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Shaw, Clare. "Nutritional aspects of advanced cancer". Palliative Medicine 6, nr 2 (kwiecień 1992): 105–10. http://dx.doi.org/10.1177/026921639200600204.

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Gould, Kathy. "Nutritional Aspects of Cancer Rehabilitation". Rehabilitation Oncology 13, nr 3 (1995): 12–21. http://dx.doi.org/10.1097/01893697-199513030-00010.

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Henderson, Maureen M. "Nutritional aspects of breast cancer". Cancer 76, S10 (15.11.1995): 2053–58. http://dx.doi.org/10.1002/1097-0142(19951115)76:10+<2053::aid-cncr2820761324>3.0.co;2-m.

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Krawczyk, Joanna, i Leszek Kraj. "Metabolic and nutritional aspects of cancer". Postępy Higieny i Medycyny Doświadczalnej 68 (22.08.2014): 1008–14. http://dx.doi.org/10.5604/17322693.1118194.

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Kalman, D., i LJ Villani. "Nutritional aspects of cancer-related fatigue." Rehabilitation Oncology 16, nr 3 (marzec 1998): 31–32. http://dx.doi.org/10.1097/01893697-199816030-00027.

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Alaejos, M. Sanz, F. J. Dı́az Romero i C. Dı́az Romero. "Selenium and cancer: some nutritional aspects". Nutrition 16, nr 5 (maj 2000): 376–83. http://dx.doi.org/10.1016/s0899-9007(99)00296-8.

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KALMAN, DOUGLAS, i LAURA J. VILLANI. "Nutritional Aspects of Cancer-Related Fatigue". Journal of the American Dietetic Association 97, nr 6 (czerwiec 1997): 650–54. http://dx.doi.org/10.1016/s0002-8223(97)00163-6.

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Hill, Michael J. "Nutritional and metabolic aspects of gastrointestinal cancer". Current Opinion in Clinical Nutrition and Metabolic Care 1, nr 5 (wrzesień 1998): 405–7. http://dx.doi.org/10.1097/00075197-199809000-00006.

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Chamberlain, Ronald S., i Yuman Fong. "Nutritional and metabolic aspects of gastrointestinal cancer". Current Opinion in Clinical Nutrition and Metabolic Care 2, nr 5 (wrzesień 1999): 381–85. http://dx.doi.org/10.1097/00075197-199909000-00005.

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Cooperman, Avram M., Jayant Chivati i Ronald S. Chamberlain. "Nutritional and metabolic aspects of pancreatic cancer". Current Opinion in Clinical Nutrition and Metabolic Care 3, nr 1 (styczeń 2000): 17–21. http://dx.doi.org/10.1097/00075197-200001000-00004.

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Pöschl, Gudrun, Felix Stickel, Xiang D. Wang i Helmut K. Seitz. "Alcohol and cancer: genetic and nutritional aspects". Proceedings of the Nutrition Society 63, nr 1 (luty 2004): 65–71. http://dx.doi.org/10.1079/pns2003323.

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Chronic alcohol consumption is a major risk factor for cancer of upper aero-digestive tract (oro-pharynx, hypopharynx, larynx and oesophagus), the liver, the colo-rectum and the breast. Evidence has accumulated that acetaldehyde is predominantly responsible for alcohol-associated carcinogenesis. Acetaldehyde is carcinogenic and mutagenic, binds to DNA and protein, destroys the folate molecule and results in secondary cellular hyper-regeneration. Acetaldehyde is produced by mucosal and cellular alcohol dehydrogenase, cytochrome P450 2E1 and through bacterial oxidation. Its generation and/or its metabolism is modulated as a result of polymorphisms or mutations of the genes responsible for these enzymes. Acetaldehyde can also be produced by oral bacteria. Smoking, which changes the oral bacterial flora, also increases salivary acetaldehyde. Cigarette smoke and some alcoholic beverages, such as Calvados, contain acetaldehyde. In addition, chronic alcohol consumption induces cytochrome P450 2E1 enxyme activity in mucosal cells, resulting in an increased generation of reactive oxygen species and in an increased activation of various dietary and environmental carcinogens. Deficiencies of riboflavin, Zn, folate and possibly retinoic acid may further enhance alcohol-associated carcinogenesis. Finally, methyl deficiency as a result of multiple alcohol-induced changes leads to DNA hypomethylation. A depletion of lipotropes, including methionine, choline, betaine and S-adenosylmethionine, as well as folate, results in the hypomethylation of oncogenes and may lead to DNA strand breaks, all of which are associated with increased carcinogenesis.

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Chan, Wynnie. "Nutritional aspects of the development of cancer". Nutrition & Food Science 30, nr 4 (sierpień 2000): 174–77. http://dx.doi.org/10.1108/00346650010329399.

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Bozzetti, Federico. "Nutritional aspects of the cancer/aging interface". Journal of Geriatric Oncology 2, nr 3 (lipiec 2011): 177–86. http://dx.doi.org/10.1016/j.jgo.2011.03.003.

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Vashura, A. Yu, A. A. Pyataeva i A. F. Karelin. "Key aspects of nutrition and nutritional support for children with malignant neoplasms after completion of cancer treatment". Voprosy detskoj dietologii 20, nr 6 (2022): 64–70. http://dx.doi.org/10.20953/1727-5784-2022-6-64-70.

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Children with malignant neoplasms are a high-risk group for developing nutritional and metabolic disorders, which are one of the key disabling factors that significantly reduce the effectiveness of medical and social rehabilitation. Dynamic monitoring, screening, and timely correction of identified problems, including nutritional ones, constitute an essential precondition for the success of rehabilitation. The basic principles of nutritional correction in pediatric oncology include the following: a personalized approach; avoidance of long intervals between meals; prescription of any restrictive diets only for reasonable indications; multidisciplinarity; sparing of the gastrointestinal tract; timely initiation of nutritional support; continuity, dynamic monitoring, and control of nutritional status. The aim of this study is to describe the main aspects of nutritional support in children with malignant neoplasms after the end of cancer treatment. Key words: children, nutritional support, oncology, nutrition, cancer

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Wiseman, Martin J. "Nutrition and cancer: prevention and survival". British Journal of Nutrition 122, nr 5 (14.09.2018): 481–87. http://dx.doi.org/10.1017/s0007114518002222.

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AbstractCancer is increasing worldwide. Patterns of cancer are also changing. The evidence is summarised in the 2018 World Cancer Research Fund/American Institute for Cancer Research report Diet, Nutrition, Physical Activity and Cancer: a Global Perspective. The plasticity of cancer patterns implicates environmental factors as determinants of cancer, and nutrition influences key cellular and molecular processes that characterise cancer. Epidemiology identifies associations between aspects of diet, nutrition, and physical activity with one or more cancers; there is evidence for plausible mechanisms that imply that these are causal. Some nutritional exposures (alcohol and processed meat) are likely causal factors, but no singular factor protects against cancer (except dietary fibre for colorectal cancer). Cancer protection mainly derives from a systemic metabolic environment that promotes healthy cell replication and tissue integrity. Such a nutritional state reflects avoiding excess adiposity through healthy dietary patterns rich in plant foods (legumes, wholegrains, pulses, vegetables and fruits), with modest meat, fish and dairy, low in alcohol and salt preserved foods, and an active way of life, avoiding sedentary behaviours. Less is known about the impact of nutritional interventions in people with a diagnosis of cancer, but nutrition including adiposity and physical activity predict breast cancer outcome. Promoting healthy ways of life requires public information and education, but alone these do not generate change; a socio-political and cultural environment that is conducive to adopting healthy behaviours is needed. Uncertainties in the evidence offer promising directions for future research, but sufficient is known to act as a basis for public policy and clinical practice.

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Furbetta, Niccolò, Annalisa Comandatore, Desirée Gianardi, Matteo Palmeri, Gregorio Di Franco, Simone Guadagni, Giovanni Caprili i in. "Perioperative Nutritional Aspects in Total Pancreatectomy: A Comprehensive Review of the Literature". Nutrients 13, nr 6 (22.05.2021): 1765. http://dx.doi.org/10.3390/nu13061765.

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Total pancreatectomy (TP) is a highly invasive procedure often performed in patients affected by anorexia, malabsorption, cachexia, and malnutrition, which are risk factors for bad surgical outcome and even may cause enhanced toxicity to chemo-radiotherapy. The role of nutritional therapies and the association between nutritional aspects and the outcome of patients who have undergone TP is described in some studies. The aim of this comprehensive review is to summarize the available recent evidence about the influence of nutritional factors in TP. Preoperative nutritional and metabolic assessment, but also intra-operative and post-operative nutritional therapies and their consequences, are analyzed in order to identify the aspects that can influence the outcome of patients undergoing TP. The results of this review show that preoperative nutritional status, sarcopenia, BMI and serum albumin are prognostic factors both in TP for pancreatic cancer to support chemotherapy, prevent recurrence and prolong survival, and in TP with islet auto-transplantation for chronic pancreatitis to improve postoperative glycemic control and obtain better outcomes. When it is possible, enteral nutrition is always preferable to parenteral nutrition, with the aim to prevent or reduce cachexia. Nowadays, the nutritional consequences of TP, including diabetes control, are improved and become more manageable.

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Schmid, H. P. "S11 Nutritional aspects of primary prostate cancer prevention". European Journal of Cancer Supplements 8, nr 2 (marzec 2010): 3–4. http://dx.doi.org/10.1016/s1359-6349(10)70747-3.

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Muscaritoli, Maurizio, Jann Arends i Matti Aapro. "From guidelines to clinical practice: a roadmap for oncologists for nutrition therapy for cancer patients". Therapeutic Advances in Medical Oncology 11 (styczeń 2019): 175883591988008. http://dx.doi.org/10.1177/1758835919880084.

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Tackling malnutrition in cancer patients remains one of the most challenging tasks in clinical practice. Even though robust evidence exists stressing the role of nutritional status in relation to treatment outcome, its appropriate consideration in clinical practice is often lacking. In this review, we discuss the significance of nutritional status and of malnutrition for the cancer patient. Drawn from experience and from current recommendations of the European Society for Clinical Nutrition and Metabolism (ESPEN), we propose concrete and manageable steps to routinely incorporate nutritional aspects in today’s oncological clinical practice.

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Snegovoy, A. V., V. B. Larionova i I. V. Kononenko. "Anorexia-cachexia syndrome in cancer patients: pathogenetic aspects and treatment options". Oncohematology 15, nr 4 (7.12.2020): 91–102. http://dx.doi.org/10.17650/1818-8346-2020-15-4-91-102.

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Background. Modern standards for the treatment of both solid tumors and tumors of the blood system provide a mandatory assessment of the objective status of the patient. One of the important criteria of which is nutritional status. Underestimating the role of nutritional support in the treatment of cancer patients leads to a deterioration of treatment results due to the progressive deterioration of nutritional status and the development of cancer anorexia cachexia syndrome (CACS), which is an independent adverse factor leading to the death of the patient. The increase in the number of cancer patients with risk factors for CACS development requires not only close attention of clinicians to this problem, but also the development of clear recommendations for the diagnosis and management of such patients. This can contribute to solving several problems at once. First, it will allow optimizing monitoring of cancer patients predisposed to CACS development during anticancer treatment. Secondly, it will provide an opportunity to develop a diagnostic algorithm to prevent it. Third, the use of the identified criteria for predicting and outcome of complications both on an outpatient basis and in a hospital will be aimed at creating favorable conditions for anticancer therapy and thereby improving long-term treatment results and patients quality of life. Studying the mechanisms of development of CACS, the possibilities of correcting this condition, indicate the need for a multimodal concept and the rejection of the search for a “magic pill”. The results of a multicenter, prospective randomized study conducted in the oncology and hematology departments of healthcare institutions.Objective: to evaluate the effectiveness of FortiCare oral nutritional support in cancer patients under the real clinical practice.Materials and methods. The study included 96 patients with stage II–IV tumors. Radiation therapy was received by 28 patients, chemotherapy ‒ by 68 patients. Patient information was collected using an individual registration card. The patients were randomized according to nutritional support tactics (1:1). In the study group, with radiation (n = 14) and chemotherapy (n = 34), patients received enteral nutrition Forticare orally 125 ml 3 times a day in parallel with their usual diet. Patients in the control group during radiation therapy (n = 14) received the required amount of calories from their usual diet. During chemotherapy, patients in the control group (n = 34) with a lack of daily calorie intake received additional parenteral nutrition.Results and conclusion. While taking FortiCare, there was a smaller loss of body weight (p ≤0.05), a frequency of mucositis of the oral cavity, and esophagitis (p >0.05). With chemotherapy, the incidence of diarrhea (p <0.001) and constipation (p <0.05) was detected less frequently than in the control group. A decrease in the frequency of hematological toxicity (leukopenia, thrombocytopenia) was noted (p >0.05).

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Talwar, B., R. Donnelly, R. Skelly i M. Donaldson. "Nutritional management in head and neck cancer: United Kingdom National Multidisciplinary Guidelines". Journal of Laryngology & Otology 130, S2 (maj 2016): S32—S40. http://dx.doi.org/10.1017/s0022215116000402.

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AbstractNutritional support and intervention is an integral component of head and neck cancer management. Patients can be malnourished at presentation, and the majority of patients undergoing treatment for head and neck cancer will need nutritional support. This paper summarises aspects of nutritional considerations for this patient group and provides recommendations for the practising clinician.Recommendations• A specialist dietitian should be part of the multidisciplinary team for treating head and neck cancer patients throughout the continuum of care as frequent dietetic contact has been shown to have enhanced outcomes. (R)• Patients with head and neck cancer should be nutritionally screened using a validated screening tool at diagnosis and then repeated at intervals through each stage of treatment. (R)• Patients at high risk should be referred to the dietitian for early intervention. (R)• Offer treatment for malnutrition and appropriate nutrition support without delay given the adverse impact on clinical, patient reported and financial outcomes. (R)• Use a validated nutrition assessment tool (e.g. scored Patient Generated–Subjective Global Assessment or Subjective Global Assessment) to assess nutritional status. (R)• Offer pre-treatment assessment prior to any treatment as intervention aims to improve, maintain or reduce decline in nutritional status of head and neck cancer patients who have malnutrition or are at risk of malnutrition. (G)• Patients identified as well-nourished at baseline but whose treatment may impact on their future nutritional status should receive dietetic assessment and intervention at any stage of the pathway. (G)• Aim for energy intakes of at least 30 kcal/kg/day. As energy requirements may be elevated post-operatively, monitor weight and adjust intake as required. (R)• Aim for energy and protein intakes of at least 30 kcal/kg/day and 1.2 g protein/kg/day in patients receiving radiotherapy or chemoradiotherapy. Patients should have their weight and nutritional intake monitored regularly to determine whether their energy requirements are being met. (R)• Perform nutritional assessment of cancer patients frequently. (G)• Initiate nutritional intervention early when deficits are detected. (G)• Integrate measures to modulate cancer cachexia changes into the nutritional management. (G)• Start nutritional therapy if undernutrition already exists or if it is anticipated that the patient will be unable to eat for more than 7 days. Enteral nutrition should also be started if an inadequate food intake (60 per cent of estimated energy expenditure) is anticipated for more than 10 days. (R)• Use standard polymeric feed. (G)• Consider gastrostomy insertion if long-term tube feeding is necessary (greater than four weeks). (R)• Monitor nutritional parameters regularly throughout the patient's cancer journey. (G)• Pre-operative:○ Patients with severe nutritional risk should receive nutrition support for 10–14 days prior to major surgery even if surgery has to be delayed. (R)○ Consider carbohydrate loading in patients undergoing head and neck surgery. (R)• Post-operative:○ Initiate tube feeding within 24 hours of surgery. (R)○ Consider early oral feeding after primary laryngectomy. (R)• Chyle Leak:○ Confirm chyle leak by analysis of drainage fluid for triglycerides and chylomicrons. (R)○ Commence nutritional intervention with fat free or medium chain triglyceride nutritional supplements either orally or via a feeding tube. (R)○ Consider parenteral nutrition in severe cases when drainage volume is consistently high. (G)• Weekly dietetic intervention is offered for all patients undergoing radiotherapy treatment to prevent weight loss, increase intake and reduce treatments interruptions. (R)• Offer prophylactic tube feeding as part of locally agreed guidelines, where oral nutrition is inadequate. (R)• Offer nutritional intervention (dietary counselling and/or supplements) for up to three months after treatment. (R)• Patients who have completed their rehabilitation and are disease free should be offered healthy eating advice as part of a health and wellbeing clinic. (G)• Quality of life parameters including nutritional and swallowing, should be measured at diagnosis and at regular intervals post-treatment. (G)

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Kolesnik, O. P., O. M. Levyk, D. Ye Cherniavskyi, V. O. Kuzmenko i L. S. Lytvynenko. "Nutrition and cancer: modern aspects of a healthy lifestyle (literature review)". Pathologia 19, nr 2 (22.08.2022): 135–41. http://dx.doi.org/10.14739/2310-1237.2022.2.258362.

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Despite significant improvements in screening, diagnosis and targeted therapy, cancer remains the second leading cause of death in the world. It is becoming increasingly clear that diet and lifestyle play a significant role in the development and progression of cancer. Thus, various dietary combinations can be proposed to reduce the risk of cancer and to improve the impact of basic therapy. Nutrition is closely linked to cancer. Food carcinogens, macronutrients, micronutrients such as vitamins A, C and D, dietary fiber, modulation of metabolism by diet, dietary supplements and anticancer agents in food affect the development of cancer. This article discusses research on the relationship between nutrition and cancer, as well as current dietary guidelines for reducing the risk of cancer. The aim of the study is to analyze information from the professional literature on the influence of various nutritional regimes in cancer patients. Conclusions. Proper nutrition can prevent the risk of cancer and improve the impact of treatment on the disease. Ketogenic diet is useful in combination with standard therapy on the basis of its ability to enhance the antitumor effects of classical chemotherapy and radiation therapy, its overall good safety and tolerability, as well as improving the quality of life. Mediterranean diet is a protective factor against cancer, due to the antioxidant and anti-inflammatory properties of the ingredients. Fasting is also a potentially effective strategy for inducing the differential stress resistance of cancer and normal cells as an adjunct to standard treatment. Promising benefits of vitamins in the prevention and treatment of cancer can be achieved through the use of new potent analogues, as well as combinations of vitamins in the early stages of cancer.

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Yari Boroujeni, R., i M. Karimzadeh. "The effect of nutritional aspects of life style on gastrointestinal cancer". European Journal of Cancer 72 (luty 2017): S158. http://dx.doi.org/10.1016/s0959-8049(17)30588-9.

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Bonde Jensen, A., B. Enig i J. Kondrup. "Attitudes towards nutritional aspects among cancer patients- a nation wide survey". European Journal of Cancer 37 (kwiecień 2001): S281. http://dx.doi.org/10.1016/s0959-8049(01)81531-8.

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Zanoaga, Oana, Cornelia Braicu, Paul Chiroi, Nutu Andreea, Nadim Al Hajjar, Simona Mărgărit, Schuyler S. Korban i Ioana Berindan-Neagoe. "The Role of miR-155 in Nutrition: Modulating Cancer-Associated Inflammation". Nutrients 13, nr 7 (29.06.2021): 2245. http://dx.doi.org/10.3390/nu13072245.

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Nutrition plays an important role in overall human health. Although there is no direct evidence supporting the direct involvement of nutrition in curing disease, for some diseases, good nutrition contributes to disease prevention and our overall well-being, including energy level, optimum internal function, and strength of the immune system. Lately, other major, but more silent players are reported to participate in the body’s response to ingested nutrients, as they are involved in different physiological and pathological processes. Furthermore, the genetic profile of an individual is highly critical in regulating these processes and their interactions. In particular, miR-155, a non-coding microRNA, is reported to be highly correlated with such nutritional processes. In fact, miR-155 is involved in the orchestration of various biological processes such as cellular signaling, immune regulation, metabolism, nutritional responses, inflammation, and carcinogenesis. Thus, this review aims to highlight those critical aspects of the influence of dietary components on gene expression, primarily on miR-155 and its role in modulating cancer-associated processes.

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Blasiak, Janusz, Jan Chojnacki, Elzbieta Pawlowska, Joanna Szczepanska i Cezary Chojnacki. "Nutrition in Cancer Therapy in the Elderly—An Epigenetic Connection?" Nutrients 12, nr 11 (1.11.2020): 3366. http://dx.doi.org/10.3390/nu12113366.

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The continuous increase in life expectancy results in a steady increase of cancer risk, which consequently increases the population of older adults with cancer. Older adults have their age-related nutritional needs and often suffer from comorbidities that may affect cancer therapy. They frequently are malnourished and present advanced-stage cancer. Therefore, this group of patients requires a special multidisciplinary approach to optimize their therapy and increase quality of life impaired by aging, cancer, and the side effects of therapy. Evaluation strategies, taking advantage of comprehensive geriatric assessment tools, including the comprehensive geriatric assessment (CGA), can help individualize treatment. As epigenetics, an emerging element of the regulation of gene expression, is involved in both aging and cancer and the epigenetic profile can be modulated by the diet, it seems to be a candidate to assist with planning a nutritional intervention in elderly populations with cancer. In this review, we present problems associated with the diet and nutrition in the elderly undergoing active cancer therapy and provide some information on epigenetic aspects of aging and cancer transformation. Nutritional interventions modulating the epigenetic profile, including caloric restriction and basal diet with modifications (elimination diet, supplementary diet) are discussed as the ways to improve the efficacy of cancer therapy and maintain the quality of life of older adults with cancer.

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Tofthagen, Cindy, Mary Tanay, Adam Perlman, Jason Starr, Pooja Advani, Katharine Sheffield i Tara Brigham. "A Systematic Review of Nutritional Lab Correlates with Chemotherapy Induced Peripheral Neuropathy". Journal of Clinical Medicine 11, nr 2 (12.01.2022): 355. http://dx.doi.org/10.3390/jcm11020355.

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Chemotherapy induced peripheral neuropathy (CIPN) is a dose-limiting side effect of chemotherapy for which no prevention or cure exists. Cancer and cancer treatments can adversely affect nutritional status. Nutrition may play a role in development of CIPN, yet the relationship between nutrition and CIPN is not well understood. Common laboratory values measuring various aspects of nutrition (hemoglobin/hematocrit, vitamin B12, calcium, and magnesium) may be associated with CIPN. The aim of this systematic review is to evaluate the empirical evidence surrounding the relationship between laboratory measures of nutrition and CIPN among persons with cancer who received neurotoxic chemotherapy drugs. We conducted an extensive review of the literature to identify articles that evaluated relationships between laboratory measures of nutrition and CIPN. A total of eleven articles satisfied the inclusion/exclusion criteria. Participants in the studies had breast or colorectal cancer, lymphoma or multiple myeloma and were receiving a variety of neurotoxic drugs. Hemoglobin/hematocrit, vitamin D, albumin, and magnesium were associated with CIPN. The quality of the studies ranges from fair to good. Evidence suggests that low levels of the above-mentioned tests could be associated with CIPN but additional research is needed.

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Morris, H., i J. Thomas. "Nutritional aspects of colorectal cancer surgery care in a district general hospital". Journal of Human Nutrition and Dietetics 22, nr 3 (czerwiec 2009): 271. http://dx.doi.org/10.1111/j.1365-277x.2009.00952_20.x.

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Durán-Poveda, Manuel, Alejandro Suárez-de-la-Rica, Emilia Cancer Minchot, Julia Ocón-Bretón, Andrés Sánchez-Pernaute i Gil Rodríguez-Caravaca. "Knowledge and Practices of Digestive Surgeons concerning Specialized Nutritional Support in Cancer Patients: A Survey Study". Nutrients 14, nr 22 (11.11.2022): 4764. http://dx.doi.org/10.3390/nu14224764.

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A survey study based on a 21-item questionnaire was conducted to assess knowledge and practices of digestive surgeons focused on nutritional support in gastrointestinal cancer patients. At least 5 staff digestive surgeons from 25 tertiary care hospitals throughout Spain were invited to participate and 116 accepted. Malnutrition was correctly defined by 81.9% of participants. In patients undergoing major abdominal surgery, 55.2% considered that preoperative nutritional support is indicated in all patients with malnutrition for a period of 7–14 days. For the diagnosis of malnutrition, only 18.1% of participants selected unintentional weight loss together with a fasting or semi-fasting period of more than one week. Regarding the advantages of enteral infusion, 93.7% of participants considered preservation of the integrity of the intestinal mucosa and barrier function, and in relation to peripheral parenteral nutrition, 86.2% selected the definition of nutrient infusion through a peripheral vein and 81.9% its indication for less than 7 days. Digestive surgeons had a limited knowledge of basic aspects of clinical nutrition in cancer patients, but there was some variability regarding clinical practice in individual cases. These findings indicate the need to develop standardized clinical protocols as well as a national consensus on nutrition support in cancer patients.

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Fakhri, Ghina, Majd Al Assaad i Arafat Tfayli. "Association of various dietary habits and risk of lung cancer: an updated comprehensive literature review". Tumori Journal 106, nr 6 (4.03.2020): 445–56. http://dx.doi.org/10.1177/0300891619900675.

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Lung cancer remains the leading cause of cancer death in both men and women worldwide. Tobacco smoking remains the single most important factor. Recent research has focused on the role of nutrition and dietary habits on lung tumorigenesis. With many individual reports on separate dietary aspects, no single review is available in the literature that summarizes the updated studies. To our knowledge, this is the first review that comprehensively reviews the updated literature on the effect of dietary habits on lung cancer. This review was concluded in February 2019 and included all meta-analyses, systematic reviews, and literature reviews. Thirty studies were retrieved in total. Items in the diet that offer a protective effect on lung parenchyma are fruits, vegetables, fish, nuts, soy, B vitamins, vitamin D, vitamin E, vitamin C, and zinc. Changing dietary habits to decrease the risk of lung cancer can be performed in parallel with smoking cessation programs. There is a need for future studies with large sample sizes to accurately evaluate some aspects of nutrition and their effect on lung cancer risk. Physicians are encouraged to provide nutritional advice to their patients.

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Zhou, Hai, Fuchen Xing i Hong Liu. "Influence of Whole-Process Nutrition Management on Nutritional Status of Patients with Esophageal Cancer Undergoing Radiotherapy". Current Topics in Nutraceutical Research 22, nr 2 (27.11.2023): 497–502. http://dx.doi.org/10.37290/ctnr2641-452x.22:497-502.

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To probe the effect of whole-process nutrition management on the nutritional status of patients with esophageal cancer undergoing radiotherapy, 100 patients were allocated to the control group (n = 50) and observation group (n = 50). Patients in both groups underwent routine treatment after admission. The control group adopted conventional nutrition management, while the observation group was given whole-process nutrition management. Compared to the control group, the patient-generated subjective global assessment score in the observation group declined after intervention (P < 0.05). Levels of prealbumin, albumin, transferrin, immunoglobulin A, immunoglobulin G, immunoglobulin M, CD3+, and CD4+ in the observation group were elevated compared to the control group after intervention (P < 0.05). According to the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30, the observation group exhibited higher scores in the aspects of family understanding and cooperation, mental condition, appetite, daily life, and sleep quality than the control group after intervention (P < 0.05). Furthermore, the incidence of adverse reactions in the observation group was lessened compared to the control group (P < 0.05). Hence, implementing whole-process nutrition management in patients undergoing radiotherapy can promote their nutritional status and quality of life.

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Mazzella, Antonio, Riccardo Orlandi, Sebastiano Maiorca, Clarissa Uslenghi, Matteo Chiari, Luca Bertolaccini, Monica Casiraghi, Giorgio Lo Iacono, Lara Girelli i Lorenzo Spaggiari. "How General and Inflammatory Status Impacts on the Prognosis of Patients Affected by Lung Cancer: State of the Art". Biomedicines 12, nr 7 (12.07.2024): 1554. http://dx.doi.org/10.3390/biomedicines12071554.

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Pulmonary cancer is often associated with systemic inflammation and poor nutritional status and these two aspects are strongly correlated and related to the scarce infiltration of a tumor by immune cells. We reviewed all English literature reviews from 2000 to 2024 from PubMed, Scopus and Google Scholar, including original articles, review articles, and metanalyses. We excluded non-English language articles and case reports/case series. Generally speaking, nutritional and inflammatory status largely affect medium and long-term prognosis in lung cancer patients. A correct stratification of patients could improve their preoperative general functional nutritional and inflammatory status, minimizing, therefore, possible treatment complications and improving long-term prognosis.

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Meiliana, Anna, Nurrani Mustika Dewi i Andi Wijaya. "Red Meats and Processed Meat as the Carcinogenic Foods and Phytochemical-chemoprevention". Indonesian Biomedical Journal 11, nr 3 (3.12.2019): 225–39. http://dx.doi.org/10.18585/inabj.v11i3.965.

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BACKGROUND: Along with its increased prevalence, in the past decade, cancer had joined the list of chronic debilitating diseases. Nutrition become substantial aspects, due to its time-dependent effect to modulate inflammation thus trigger carcinogenic effects by altering the immune check point. Thus, nutrition contributes to the progression and therapeutic response of cancer, both in human or animal models.CONTENT: Meat is well favored food with appreciable appealing. Due to its high nutritional values it plays a central role in human development. Meat or meat derivate are important sources of proteins, minerals and vitamins. Their nutritional importance is worth compare to their economic impact but recent publication of WHO has set the social alarm about the relationship between red and/or processed meat consumption and cancer. On the other side, some natural or biologic agents may inhibit or reverse tumor growth. Some phytochemical agents including curcumin, resveratrol, lycopene, folates and tea polyphenols clinically proved to tune the signaling pathways regulating cell proliferation and apoptosis in transformed cells, enhance the host immune system and sensitize malignant cells to cytotoxic agents.SUMMARY: Recent studies on chemopreventive agents involves a wide range of molecules, natural (plants, fruits and vegetables) or synthetic will provide better insights for cancer early pathogenesis, important end-point biomarker, and finally potential for reducing the burden of cancer.KEYWORDS: blocking agents, suppressing agents, red meat, processed meat, chemoprevention, phytochemicals

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Baldwin, Christine. "The effectiveness of nutritional interventions in malnutrition and cachexia". Proceedings of the Nutrition Society 74, nr 4 (19.06.2015): 397–404. http://dx.doi.org/10.1017/s0029665115002311.

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Cancer is a common diagnosis and leading cause of death worldwide. Amounts of weight loss vary but it is associated with considerable morbidity, poorer quality of life and reduced survival. Nutritional intervention has the potential to maximise response to treatment and improve functioning and quality of life. The aim of this paper was to review the evidence for oral nutritional interventions in the management of weight loss in patients with cancer. Comparison of studies of nutritional support interventions in people with cancer is complicated by variations in understanding of what constitutes a compromised nutritional status. There are similarities and differences between definitions of both malnutrition and cachexia and studies of oral nutritional interventions have failed to use standard criteria at study inclusion contributing to heterogeneity amongst studies. Meta-analysis of randomised controlled trials has suggested limited evidence of benefit to nutritional and clinical outcomes but some improvements to aspects of quality of life. The presence of cachexia in patients with cancer might explain the limited efficacy of simple oral nutritional interventions, which lack a component designed to address metabolic abnormalities associated with cachexia. Novel strategies combining nutritional support with therapeutic agents designed to down-regulate the metabolic aberrations have failed to demonstrate consistent benefits and the results of multimodal treatments combining several interventions are awaited. There is a need for intervention studies recruiting patients early in the disease course, which underlines the need for definitions which predict poor outcome and hence allow early recognition of vulnerable patients.

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González Gross, Marcela. "Research challenges on the interaction between exercise and nutrition". Anales de la Real Academia Nacional de Farmacia 87, nr 87(04) (2021): 395–402. http://dx.doi.org/10.53519/analesranf.2021.87.04.03.

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The increase in life expectancy and non-communicable chronic diseases (obesity, type 2 diabetes, cardiovascular diseases, cancer, dementia, depression, among other) have led to both Sports and Nutrition Sciences gaining importance in research and in Public Health. But the lack of connection and collaboration between these areas has caused most scientific studies to analyze these aspects separately. The current state of scientific knowledge seems to indicate that it is reasonable to address them jointly, although new questions clearly arise in the combination of both. The combined effect between nutrients and physiological stimuli of training loads are not the same in all people, since there is an individualized response motivated by genetic and epigenetic aspects. Therefore, we must be able to identify responders and non-responders to nutritional and exercise interventions. Among the many challenges that arise today, we find the complexity of the energy balance, for many years misunderstood as a mathematical equation; the effect that physical activity or its absence has on habits and nutritional status; sarcopenia and osteoporosis; sarcopenic obesity; microbiota; cognitive impairment; and mortality.

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Yu.A., Fefelova,. "THE ROLE OF NUTRITIONAL RESTRICTION IN THE PATHOGENESIS OF MALIGNANT TUMORS". CARDIOMETRY, nr 24 (30.11.2022): 12–13. http://dx.doi.org/10.18137/cardiometry.2022.24.conf.5.

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Cancer is one of the leading causes of death in developed countries. Cancer incidence is growing, and it may be associated with longer life expectancy that leads to higher risk of cancer development. Metabolic changes are among the most important aspects of the tumor progression, which appear both in the tumor cells themselves and in the tumor microenvironment, affecting later the entire organism as a whole. Abnormal metabolism of tumor cells, including activation of aerobic glycolysis and enhancement of anabolic pathways, is important in metastasizing, medical drug resistance, and in the implementation of tumor stem cell viability programs.

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Adkar, Prafulla P., i V. H. Bhaskar. "Pandanus odoratissimus(Kewda): A Review on Ethnopharmacology, Phytochemistry, and Nutritional Aspects". Advances in Pharmacological Sciences 2014 (2014): 1–19. http://dx.doi.org/10.1155/2014/120895.

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Pandanus odoratissimusLinn. (family: Pandanaceae) is traditionally recommended by the Indian Ayurvedic medicines for treatment of headache, rheumatism, spasm, cold/flu, epilepsy, wounds, boils, scabies, leucoderma, ulcers, colic, hepatitis, smallpox, leprosy, syphilis, and cancer and as a cardiotonic, antioxidant, dysuric, and aphrodisiac. It contains phytochemicals, namely, lignans and isoflavones, coumestrol, alkaloids, steroids, carbohydrates, phenolic compounds, glycosides, proteins, amino acids as well as vitamins and nutrients, and so forth. It is having immense importance in nutrition. A 100 g ediblePandanuspericarp is mainly comprised of water and carbohydrates (80 and 17 g, resp.) and protein (1.3 mg), fat (0.7 mg), and fiber (3.5 g).Pandanusfruits paste provides 321 kilocalories, protein (2.2 g), calcium (134 mg), phosphorus (108 mg), iron (5.7 mg), thiamin (0.04 mg), vitamin C (5 mg), and beta-carotene (19 to 19,000 μg) (a carotenoid that is a precursor to vitamin A).Pandanusfruit is an important source of vitamins C, B1, B2, B3, and so forth, usually prepared as aPandanusfloured drink. Traditional claims were scientifically evaluated by the various authors and the phytochemical profile of plant parts was well established. The methods for analytical estimations were developed. However, there is paucity of systematic compilation of scientifically important information about this plant. In the present review we have systematically reviewed and compiled information of pharmacognostic, ethnopharmacology, phytochemistry, pharmacology, nutritional aspects, and analytical methods. This review will enrich knowledge leading the way into the discovery of new therapeutic agents with improved and intriguing pharmacological properties.

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Bell, S. J., E. A. Mascioli, R. A. Forse i B. R. Bistrian. "Nutrition support and the human immunodeficiency virus (HIV)". Parasitology 107, S1 (styczeń 1993): S53—S67. http://dx.doi.org/10.1017/s0031182000075508.

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SUMMARYNutritional support of patients with HIV or acquired immune deficiency syndrome (AIDS) has many similarities to other disease states in that the same nutritional products and techniques are used. Some patients with HIV, and many with AIDS without secondary infection, experience a metabolic milieu similar to patients with cancer cachexia. In providing dietary counselling to the HIV patient, we encounter many of the obstacles that must be overcome to improve nutrition in cancer: anorexia, gastrointestinal discomfort, lethargy, and poor nutrient utilization, which limit the ability for nutritional repletion. When a secondary infection is superimposed on HIV, patients resemble more highly catabolic trauma patients or patients in the intensive care unit (ICU), where, despite aggressive efforts to feed, there is usually a net nitrogen wasting leading to the more rapid development of cachexia. However, even in this setting, feeding will limit substantially net catabolism when compared to total starvation. Because the nutritional needs of HIV patients vary greatly, individual strategies have to be designed as the patient moves through the stages of disease. Patients are generally able to consume adequate nutrition either as regular food or dietary supplements during the latency period of viral replication. Once secondary infections become prevalent, artificial diets administered by tube or by vein may be required during the period of active secondary infections, with dietary supplements often helpful during more quiescent periods. Patients with HIV are among the most challenging for clinicians providing nutritional support. Knowledge from treatment of patients with other diseases may be useful, but more data must be gathered on the unique aspects of aetiology and treatment of the anorexia, malabsorption, and ultimate wasting associated with AIDS.

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Kano, Yosuke, Manabu Ohashi i Souya Nunobe. "Laparoscopic Function-Preserving Gastrectomy for Proximal Gastric Cancer or Esophagogastric Junction Cancer: A Narrative Review". Cancers 15, nr 1 (3.01.2023): 311. http://dx.doi.org/10.3390/cancers15010311.

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Function-preserving procedures to maintain postoperative quality of life are an important aspect of treatment for early gastric cancer. Laparoscopic proximal gastrectomy (LPG) and laparoscopic distal gastrectomy with a small remnant stomach, namely laparoscopic subtotal gastrectomy (LsTG), are alternative function-preserving procedures for laparoscopic total gastrectomy of early proximal gastric cancer. In LPG, esophagogastrostomy with techniques to prevent reflux and double-tract and jejunal interposition including esophagojejunostomy is usually chosen for reconstruction. The double-flap technique is currently a preferred reconstruction technique in Japan as an esophagogastrostomy approach to prevent reflux esophagitis. However, standardized reconstruction methods after LPG have not yet been established. In LsTG, preservation of the esophagogastric junction and the fundus prevents reflux and malnutrition, which may maintain quality of life. However, whether LsTG is an oncologically and nutritionally acceptable procedure compared with laparoscopic total gastrectomy or LPG is a concern. In this review, we summarize the status of reconstruction in LPG and the oncological and nutritional aspects of LsTG as a function-preserving gastrectomy for early proximal gastric or esophagogastric junction cancer.

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Argilés, Josep M., Francisco Javier López-Soriano, Britta Stemmler i Sílvia Busquets. "Novel targeted therapies for cancer cachexia". Biochemical Journal 474, nr 16 (27.07.2017): 2663–78. http://dx.doi.org/10.1042/bcj20170032.

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Anorexia and metabolic alterations are the main components of the cachectic syndrome. Glucose intolerance, fat depletion, muscle protein catabolism and other alterations are involved in the development of cancer cachexia, a multi-organ syndrome. Nutritional approach strategies are not satisfactory in reversing the cachectic syndrome. The aim of the present review is to deal with the recent therapeutic targeted approaches that have been designed to fight and counteract wasting in cancer patients. Indeed, some promising targeted therapeutic approaches include ghrelin agonists, selective androgen receptor agonists, β-blockers and antimyostatin peptides. However, a multi-targeted approach seems absolutely essential to treat patients affected by cancer cachexia. This approach should not only involve combinations of drugs but also nutrition and an adequate program of physical exercise, factors that may lead to a synergy, essential to overcome the syndrome. This may efficiently reverse the metabolic changes described above and, at the same time, ameliorate the anorexia. Defining this therapeutic combination of drugs/nutrients/exercise is an exciting project that will stimulate many scientific efforts. Other aspects that will, no doubt, be very important for successful treatment of cancer wasting will be an optimized design of future clinical trials, together with a protocol for staging cancer patients in relation to their degree of cachexia. This will permit that nutritional/metabolic/pharmacological support can be started early in the course of the disease, before severe weight loss occurs. Indeed, timing is crucial and has to be taken very seriously when applying the therapeutic approach.

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Baldi, Simone, Marta Tristán Asensi, Marco Pallecchi, Francesco Sofi, Gianluca Bartolucci i Amedeo Amedei. "Interplay between Lignans and Gut Microbiota: Nutritional, Functional and Methodological Aspects". Molecules 28, nr 1 (1.01.2023): 343. http://dx.doi.org/10.3390/molecules28010343.

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Lignans are non-flavonoid polyphenols present in a wide range of foods frequently consumed in the Western world, such as seeds, vegetables and fruits, and beverages such as coffee, tea and wine. In particular, the human gut microbiota (GM) can convert dietary lignans into biologically active compounds, especially enterolignans (i.e., enterolactone and enterodiol), which play anti-inflammatory and anti-oxidant roles, act as estrogen receptor activators and modulate gene expression and/or enzyme activity. Interestingly, recent evidence documenting those dietary interventions involving foods enriched in lignans have shown beneficial and protective effects on various human pathologies, including colorectal and breast cancer and cardiovascular diseases. However, considering that more factors (e.g., diet, food transit time and intestinal redox state) can modulate the lignans bioactivation by GM, there are usually remarkable inter-individual differences in urine, fecal and blood concentrations of enterolignans; hence, precise and validated analytical methods, especially gas/liquid chromatography coupled to mass spectrometry, are needed for their accurate quantification. Therefore, this review aims to summarize the beneficial roles of enterolignans, their interaction with GM and the new methodological approaches developed for their evaluation in different biological samples, since they could be considered future promising nutraceuticals for the prevention of human chronic disorders.

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Öztekin, Merve, Birsen Yılmaz, Duygu Ağagündüz i Raffaele Capasso. "Overview of Helicobacter pylori Infection: Clinical Features, Treatment, and Nutritional Aspects". Diseases 9, nr 4 (23.09.2021): 66. http://dx.doi.org/10.3390/diseases9040066.

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Helicobacter pylori (H. pylori) is a 0.5–1 µm wide, 2–4 µm long, short helical, S-shaped Gram-negative microorganism. It is mostly found in the pyloric region of the stomach and causes chronic gastric infection. It is estimated that these bacteria infect more than half of the world’s population. The mode of transmission and infection of H. pylori is still not known exactly, but the faecal–oral and oral–oral routes via water or food consumption are thought to be a very common cause. In the last three decades, research interest has increased regarding the pathogenicity, microbial activity, genetic predisposition, and clinical treatments to understand the severity of gastric atrophy and gastric cancer caused by H. pylori. Studies have suggested a relationship between H. pylori infection and malabsorption of essential micronutrients, and noted that H. pylori infection may affect the prevalence of malnutrition in some risk groups. On the other hand, dietary factors may play a considerably important role in H. pylori infection, and it has been reported that an adequate and balanced diet, especially high fruit and vegetable consumption and low processed salty food consumption, has a protective effect against the outcomes of H. pylori infection. The present review provides an overview of all aspects of H. pylori infection, such as clinical features, treatment, and nutrition.

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Casirati, Amanda, Valentina Da Prat, Arianna Bettiga, Lucia Aretano, Francesco Trevisani, Emanuele Cereda, Alberto Briganti i in. "Immunonutrition in Radical Cystectomy: State of the Art and Perspectives". Cancers 15, nr 14 (24.07.2023): 3747. http://dx.doi.org/10.3390/cancers15143747.

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Preoperative nutritional status is a pivotal aspect to consider in patients with cancer undergoing radical cystectomy (RC), as those at risk of malnutrition or already malnourished are more prone to post-surgical complications. The loss of muscle mass is a major consequence of cancer-related malnutrition. It is associated with increased risk of hospital readmission, longer hospitalization, and higher mortality. Nowadays, the close relationship between nutritional and immunological aspects under stressful conditions, such as surgery, represents an emerging scientific and clinical issue. Indeed, the synergistic action of reduced food intake and systemic inflammation generates metabolic derangements with tissue catabolism, including skeletal muscle breakdown, which is, in turn, associated with immune system dysfunction. In order to offer an additional immune-nutritional boost to the post-surgical phase, particularly in malnourished patients, nutritional support may include oral nutritional supplements and/or enteral formulas enriched with specific nutrients such as omega-3 fatty acids, arginine, glutamine, and nucleotides, with acknowledged immune-modulating effects. In the present narrative review, we addressed the state of the art of the available scientific literature on the benefit of immunonutrition in patients undergoing RC for cancer and suggest possible future perspectives to be explored. Although the role of immunonutrition was found to be little explored in the context of urologic oncology, the preliminary available data on radical cystectomy, summarized in the present paper, are promising and suggest that it may improve postoperative outcomes through immunomodulation, regardless of nutritional status before surgery.

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Muhamed, Ahmed Nuru, Berihun Bante Tesema, Endalk Getasew Hiruy, Sahlu Mitku Shiferaw, Dessie Temesgen Aycheh i Melsew Dagne Abate. "Nutritional Status and Its Determinants among Adult Cancer Patients Undergoing Chemotherapy Treatment at Hawassa University Comprehensive Specialized Hospital, Hawassa, Southern Ethiopia". Journal of Nutrition and Metabolism 2022 (28.09.2022): 1–8. http://dx.doi.org/10.1155/2022/8740272.

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Background. Malnutrition is a common problem in cancer patients. It has an impact on all aspects of the patient's life such as increasing the risk of infection, treatment toxicity, hospital stay, and health-care costs. Factors influencing the nutritional status of adult cancer patients undertaking chemotherapy treatment in Ethiopia have not been thoroughly investigated. As a result, the purpose of this study is to assess the nutritional status and its determinants among adult cancer patients undergoing chemotherapy treatment at Hawassa University Comprehensive Specialized Hospital. Objectives. The objective of this study is to determine the nutritional status and its determinants among adult cancer patients undergoing chemotherapy treatment at Hawassa University Comprehensive Specialized Hospital. Methods. A cross-sectional study was conducted among adult cancer patients undergoing chemotherapy treatment at Hawassa University Comprehensive Specialized Hospital Oncology Treatment Center, from January to May 2021. The data were gathered through a face-to-face interview and chart review method. Epi Data 4.6 was used to enter the data, which was then exported to SPSS version 25 for statistical analysis. Multivariable logistic regression analysis was used to determine the association between nutritional status and potential risk factors. A P value less than 0.05 was used to determine statistical significance. Result. This study revealed that 48.1% of participants have some level of malnutrition. Lowest wealth index AOR 0.06 (0.016–0.2), food insecurity AOR 0.1 (0.05–0.24), vomiting AOR 0.2 (0.110–.444), poor appetite AOR 0.2 (0.11–0.44), no diarrhea AOR 2.6 (1.34–5.00), and poor functioning AOR 0.3 (0.2–0.54) were significantly associated with good nutritional status. Conclusion and Recommendation. The prevalence of malnutrition among adult cancer patients undergoing chemotherapy treatment at HUCSH was high. Wealth index, food security, poor appetite, diarrhea, and performance status were significantly correlated with the nutritional status of the patients. To improve the patient’s nutritional status, economic support, early nutritional screening, and assessment, management of chemotherapy-induced symptoms should be considered.

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Collins, Nicholas. "Dietary Regulation of Memory T Cells". International Journal of Molecular Sciences 21, nr 12 (19.06.2020): 4363. http://dx.doi.org/10.3390/ijms21124363.

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Memory T cells are a fundamental component of immunological memory, providing rapid and potent host protection against secondary challenges. As such, memory T cells are key targets in the design of vaccination strategies and cancer immunotherapies, making it critical to understand the factors and mechanisms that regulate their biology. Diet is an environmental feature that impacts virtually all aspects of host physiology. However, the influence of specific dietary regiments and nutritional components on the immune system is only just starting to be uncovered. This article will review literature regarding the impact of diet and nutrition on memory T cell development, maintenance and function. It was recently shown that caloric restriction without undernutrition enhances memory T cell function, while diets high in fiber are also beneficial. However, memory T cell responses are dysfunctional in extreme nutritional states, such as undernutrition and diet-induced obesity. Therefore, diet and host nutritional status are major regulators of memory T cell biology and host fitness. To define the dietary balance required to promote optimal memory T cell responses could allow for the implementation of rational diet-based therapies that prevent or treat disease. Furthermore, that certain dietary regiments can enhance memory T cell function indicates the possibility of harnessing the underlying mechanisms in the design of novel vaccination strategies and cancer immunotherapies.

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Gerber, Mariette, Sylvia Richardson, Pierrette Crastes De Paulet, Henri Pujol i André Crastes De Paulet. "Relationship between vitamin E and polyunsaturated fatty acids in breast cancer. Nutritional and metabolic aspects". Cancer 64, nr 11 (1.12.1989): 2347–53. http://dx.doi.org/10.1002/1097-0142(19891201)64:11<2347::aid-cncr2820641126>3.0.co;2-v.

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Seabra, Larissa Mont'Alverne Jucá, i Lucia Fátima Campos Pedrosa. "Astaxanthin: structural and functional aspects". Revista de Nutrição 23, nr 6 (grudzień 2010): 1041–50. http://dx.doi.org/10.1590/s1415-52732010000600010.

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Astaxanthin, a carotenoid belonging to the xanthophyll class, has stirred great interest due to its antioxidant capacity and its possible role in reducing the risk of some diseases. Astaxanthin occurs naturally in microalgae, such as Haematococcus pluvialis and the yeast Phaffia rhodozyma, and has also been considered to be the major carotenoid in salmon and crustaceans. Shrimp processing waste, which is generally discarded, is also an important source of astaxanthin. The antioxidant activity of astaxanthin has been observed to modulate biological functions related to lipid peroxidation, having beneficial effects on chronic diseases such as cardiovascular disease, macular degeneration and cancer. Researches have shown that both astaxanthin obtained from natural sources and its synthetic counterpart produce satisfactory effects, but studies in humans are limited to natural sources. There is no established nutritional recommendation regarding astaxanthin daily intake but most studies reported beneficial results from a daily intake of 4mg. Thus, this review discusses some aspects of the carotenoid astaxanthin, highlighting its chemical structure and antioxidant activity, and some studies that report its use in humans.

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Marteau, P., i M. C. Boutron-Ruault. "Nutritional advantages of probiotics and prebiotics". British Journal of Nutrition 87, S2 (maj 2002): S153—S157. http://dx.doi.org/10.1079/bjn2002531.

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The potential ‘nutritional advantages’ of probiotics and prebiotics consist of preventive, and sometimes curative, effects against certain diseases. The evidence supporting such advantages, which requires randomised controlled trials and consistency of results from study to study, is rapidly increasing. This article summarizes the effects against diseases of intestinal origin. There is a high level of evidence for positive effects of some prebiotics to alleviate constipation and treat hepatic encephalopathy. Interesting aspects, but with a lower level of evidence at the present time, include prevention of colon cancer, intestinal infection, and recurrence of inflammatory bowel disease. There is a high level of evidence for positive effects of some probiotics in the alleviation of lactose intolerance, antibiotic-associated intestinal disorders and gastroenteritis. Evidence is rapidly growing regarding the prevention of recurrence of inflammatory bowel diseases. Positive trials have suggested preventive effects against intestinal colonization with specific gut pathogens includingClostridium difficileandHelicobacter pylori.

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Rizqiyah, Arisa, i Rijanti Abdurrachim. "Hubungan Asupan Makanan, Status Gizi, Lama Menjalani Kemoterapi dan Dukungan Keluarga dengan Kualitas Hidup Pasien Kanker Payudara (Studi di Rumah Sakit Umum Daerah Ulin Kota Banjarmasin)". Jurnal Kesehatan Indonesia 13, nr 1 (19.11.2022): 6. http://dx.doi.org/10.33657/jurkessia.v13i1.749.

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Background: Breast cancer certainly has a big impact on the sufferer, physically, psychologically, socially, spiritually and other aspects of life. This certainly affects the quality of life of breast cancer patients. Objective: To analyze the relationshipbetween food intake, nutritional status, duration of chemotherapy and family support with the quality of life of breast cancer patients at Ulin Hospital Banjarmasin. Methods: observational analytic using a cross sectional research design. The population was all breast cancer patients at Ulin Hospital Banjarmasin were 92 people based on data in December 2019. The sample was taken using a non-probability sampling technique based on inclusion and exclusion criteria as many as 48 people. Primary data were obtained through interviews and anthropometric measurements. Data analysis used Spearman Rank correlation test with 95% confidence level. Results: Energy intake deficit (70.9%), protein intake deficit (54.1%), fat intake deficit (68.8%), carbohydrate intake deficit (66.7%), nutritional status normal (47.9% ), chemotherapy 3 months (72.9%), good family support (91.7%) and moderate quality of life (75%). Conclusion: There is a relationship between food intake, nutritional status and duration of chemotherapy with the quality of life of breast cancer patients at Ulin Hospital Banjarmasin and there is no relationship between family support and quality of life of breast cancer patients at Ulin Hospital Banjarmasin. Suggestion: Nutritionists are expected to provide nutritional consultation regarding food intake for cancer patients, respondents are expected to increase food intake, and respondentâ€™s families are expected to pay attention to the patient's diet and provide information support.

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Glimelius, Bengt, Gunnar Birgegård, Katarina Hoffman, Christina Hägnebo, Gunilla Högman, Gerd Kvale, Karin Nordin, Enn Nõu, Christina Persson i Per-olow Sjödén. "Improved Care of Patients with Small Cell Lung Cancer Nutritional and Quality of Life Aspects". Acta Oncologica 31, nr 8 (styczeń 1992): 823–31. http://dx.doi.org/10.3109/02841869209089714.

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Nakauchi, Masaya, Koichi Suda, Susumu Shibasaki, Yoshinori Ishida, Kazuki Inaba i Ichiro Uyama. "Laparoscopic Subtotal Gastrectomy for Advanced Gastric Cancer: Technical Aspects and Surgical, Nutritional, and Oncological Outcomes". Journal of the American College of Surgeons 225, nr 4 (październik 2017): e56-e57. http://dx.doi.org/10.1016/j.jamcollsurg.2017.07.671.

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