Rozprawy doktorskie na temat „Biosensor”
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Nightingale, Joshua Ryan. "Optical biosensors SPARROW biosensor and photonic crystal-based fluorescence enhancement /". Morgantown, W. Va. : [West Virginia University Libraries], 2008. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=5818.
Pełny tekst źródłaTitle from document title page. Document formatted into pages; contains vi, 120 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 91-100).
Rogerson, Jonathan G. "Biosensor technology : applications in microbial toxicology". Thesis, University of Bedfordshire, 1997. http://hdl.handle.net/10547/621817.
Pełny tekst źródłaRavindran, Ramasamy. "An electronic biosensing platform". Diss., Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/44774.
Pełny tekst źródłaLias, R. J. "A conductimetric biosensor". Thesis, University of Cambridge, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.373268.
Pełny tekst źródłaColby, Edward Grellier. "A smart biosensor". Thesis, University of Cambridge, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368100.
Pełny tekst źródłaArnold, Peter Thomas. "A monolithic biosensor". Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307060.
Pełny tekst źródłaBadescu, George Octavian. "Phytohormone biosensor development". Thesis, University of Warwick, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.487811.
Pełny tekst źródłaMiller, Kevin, Jeremy Williams i James Nimlos. "PORTABLE GLUTEN BIOSENSOR". Thesis, The University of Arizona, 2009. http://hdl.handle.net/10150/192520.
Pełny tekst źródłaHOWARD, SHAUN CHRISTOPHER. "PHASE SEPARATION IN MIXED ORGANOSILANE MONOLAYERS: A MODEL SYSTEM FOR THE DEVELOPMENT OF NOVEL MEMBRANES". University of Cincinnati / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1123873986.
Pełny tekst źródłaHabermüller, Katja-Carola. "Modifizierte Polypyrrolfilme als Basis einer adaptierbaren Sensorarchitektur für reagenzlose Biosensoren". [S.l. : s.n.], 1999. http://deposit.ddb.de/cgi-bin/dokserv?idn=959536183.
Pełny tekst źródłaStengel, Gudrun. "Real time monitoring of DNA hybridization and replication using optical and acoustic biosensors". [S.l. : s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=971304572.
Pełny tekst źródłaLoose, Elizabeth. "Biosensor stabilization using hypersolutes". Thesis, Cranfield University, 2009. http://dspace.lib.cranfield.ac.uk/handle/1826/12479.
Pełny tekst źródłaScott, Manuela. "Electropolymerisation in biosensor design". Thesis, University of Southampton, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242106.
Pełny tekst źródłaSteinberg, Matthew David. "An implantable glucose biosensor". Thesis, University of Cambridge, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625092.
Pełny tekst źródłaPeng, Haiqing. "The Performance of Silicon Based Sensor and its Application in Silver Toxicity Studies". Thesis, University of North Texas, 2000. https://digital.library.unt.edu/ark:/67531/metadc2613/.
Pełny tekst źródłaZörgiebel, Felix. "Silicon Nanowires for Biosensor Applications". Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-230675.
Pełny tekst źródłaNanostructures have attracted great attention not only in scientific research, but also in engineering applications during the last decades. Especially in combination with biological systems, whose complex function is controlled from nanoscale building blocks, nanotechnological developments find a huge field of applications in the medical sector. This work is dedicated to the functional understanding and technical implementation of silicon nanowires for future medical sensor applications. In contrast to doped silicon nanowire based sensors, this work is focussed on pure, undoped silicon nanowires, which have lower demands on production techniques and use Schottky-barriers as electric field detectors. The pH and biosensing capabilities of such undoped silicon nanowire field effect transistors were investigated theoretically and experimentally and further integrated in a lab-on-a-chip device as well as a small-scale multiplexer measurement device. In a second separate part, the optical sensing properties of undoped silicon nanowires were theoretically modeled. The main contents of both parts are shortly described in the following paragraphs. A multiscale model of silicon nanowire FETs to describe the charge transport in liquid surrounding in a quantum mechanical framework was developed to investigate the sensing properties of the nanowire sensors in general. The model set the basis for the understanding of the subsequent experimental investigations of noise characterization, pH sensitivity and biosensing properties. With the help of a novel gate sweeping measurement method the optimal working point of the sensors was determined and the high sensor quality could be quantified in terms of an empirical mathematical model. The sensor was then used for measurements of medically relevant concentrations of the Thrombin protein, providing a proof-of-concept for medical applications for our newly developed sensor. In order to exploit the small size of our sensors for technical applications we integrated the devices in lab-on-a-chip system with a microfluidic droplet generation module. There they were used to measure the pH and ionic concentration of droplets. Finally a portable multiplex measurement device for silicon nanowire sensors as well as other ion sensitive FETs was developed in cooperation with the IAVT at TU Dresden (Institut für Aufbau- und Verbindungstechnik). The second part of this thesis investigates the usability of silicon nanowires for optical sensor applications from a theoretical point of view. Therefore a method for the extraction of Raman and Infrared spectra from molecular dynamics simulations was developed. The method was applied to undoped silicon nanowires and shows that the surface properties of the nanowires has a significant effect on optical spectra. These results demonstrate the relevance of semiconductor nanostructures for applications in optical spectroscopy
Clayton, Kate. "Novel polythiophenes for biosensor applications". Thesis, University of Huddersfield, 2011. http://eprints.hud.ac.uk/id/eprint/11677/.
Pełny tekst źródłaYuan, Yong J., University of Western Sydney i School of Civic Engineering and Environment. "Novel polypyrrole-based formate biosensor". THESIS_XXXX_CEE_Yuan_Y.xml, 1998. http://handle.uws.edu.au:8081/1959.7/283.
Pełny tekst źródłaDoctor of Philosophy (PhD)
Carlyon, Elizabeth Emma. "Towards an integrated optical biosensor". Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315735.
Pełny tekst źródłaJomaa, Tarek Chaker. "Instrumentation electronics for biosensor applications". Thesis, Cardiff University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.344011.
Pełny tekst źródłaIngley, Paul Michael. "Novel biosensor systems in yeast". Thesis, University of Leeds, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.426781.
Pełny tekst źródłaHarris, Richard David. "Waveguide surface plasmon resonance biosensor". Thesis, University of Southampton, 1996. https://eprints.soton.ac.uk/398739/.
Pełny tekst źródłaSETH, GAUTAM. "Adjustable Gap Micro-Electrode Biosensor". University of Cincinnati / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1186371515.
Pełny tekst źródłaPathak, Shantanu. "Resonant optical waveguide biosensor characterization". Morgantown, W. Va. : [West Virginia University Libraries], 2004. https://etd.wvu.edu/etd/controller.jsp?moduleName=documentdata&jsp%5FetdId=3792.
Pełny tekst źródłaTitle from document title page. Document formatted into pages; contains viii, 109 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 107-109).
Dondapati, Srujan Kumar. "Electrochemically controlled patterning for biosensor arrays". Doctoral thesis, Universitat Rovira i Virgili, 2006. http://hdl.handle.net/10803/8544.
Pełny tekst źródłaThere is an increasing demand of multianalyte sensing devices having potential applications in biomedical, biotechnological, industrial and environmental fields. A good spatial control during biomolecule deposition step is strictly necessary; each biomolecule has to be precisely deposited on the surface of the relevant sensor (eg., an amperometric transducer), avoiding mixing that can compromise the biosensor specificity. The aim of this thesis is to develop different patterning methods for the selective immobilization of biomolecules. The first method is selective electrodeposition of biofunctionalized Au nanoparticles for biosensor arrays. This is an electrochemically controlled patterning method where the Au nanoparticles modified by the enzymes initially and later the enzyme modified Au nanoparticles were electrodeposited selectively on the electrode surface. As a part of this methodology, initially biofunctionalized Au nanoparticles were prepared using three different approcahes. One is Au-thiol dative bonding, the second is direct adsorption and finally electrostatic layerby- layer approach. Different biomolecules like horse radish peroxidase(HRP), glucose oxidase (GOX), bovine serum albumin(BSA), and finally fluorescence labelled oilgonucleotide thiols were used to attch to the Au nanoparticles. Biofunctionalized Au nanoparticles were characterized by different techniques like zeta sizer, UV-Vis spectroscopy, transmission electron microscopy (TEM). UV-Vis spectroscopy showed the successfull modification of Au nanoparticles with a characterstic surface plasmon peak related to the stability. By using zeta sizer, layer-by-layer modification of the Au nanoparticles with redox polymer and enzymes were characterized successfully. Changes of the Au nanoparticles modified with BSA was characterised at different pH s by using the zeta sizer. After the preparation of biofunctionalized particles, some fundamental studies were done with electrodeposition of Au nanoparticles modified with medically important BSA, redox polymer to see how different parameters like potential, time of deposition, interelectrode distance, counter electrode sized, pH, effect the electrodeposition. As a part of these fundamental studies Au colloids modified with HRP and GOX were deposited for studying the electrocalaytic behaviour of the enzymes on the Au nanoparticles after electrodeposition. Later this methodology was applied for creating biosensor arrays by using two different approaches. In the first approach, GOX and HRP functionalized redox polymer modified Au nanoparticles were electrodeposited successfully on an interdigitated electrode (IDE) array with complete absence of non-specific response. In the second approach the particles were modified with an extra redox polymer layer and proved that there is complete absence of nonspecific response after electrodeposition. Moreover, this patterning methodology is generic and can be used for production of different biochips. The second method is another electrochemically controlled patterning method where the electrodes were immobilized with self assembled monolayers with electroactive functionalities which can be tunable with potentials. In this methodology, electroactive self-assembled monolayer contains an active ligand aldehyde which can be readily conjugated to the primary amine group of the biomolecule is protected in the form of acetal. Later when a active potential was applied to the underlying electrode surface, the acetal functionality is deprotected to reveal the aldehyde functionality which was further conjugated to the biomolecule. Two enzymes GOX, HRP were used as model proteins to prove the versatility of this technique. Amperometric as well as real time measurements proved the selective applicability of this technique for creation of biosensor arrays. The third methodology is also an electrochemically controlled patterning methodology where the special advantage of the electrochemically-controlled immobilization of the 4,4-bipyridyl was taken as base for the creation of biosensor arrays. In this methodology, carboxylic acid functionalised 4,4, bipyridyl molecules were synthesized and characterized by electrochemistry. Later the biomolecules were conjugated to these special molecules for the creation of sensor arrays. Proof of selectivity was shown using colourimetrically with minimal non-specific response. Finally in the fourth method which is based on the photolithography technique, two different oxidases GOX & SOX were patterned along with redox polymer selectively on an IDE array using the lift off process with complete absence of cross-talk. As a part of this methodology, different immobilization methods were optimized initially for checking the best optimisation strategy. Later different reagents were tried to optimise the best reagent that prevents the non-specific adsorption. Later this optimised system was applied on the pholithographically created IDE array. Sarcosine and glucose sensors responded selectively to their substrates with complete absence of cross talk. This thesis is structured in 7 chapters. Chapter 1 establishes to basics of the biosensor arrays, electrochemically controlled patterning methods, other selectively patterned methods, photolithography and summary of this thesis. Chapter 2 describes about the gold colloid synthesis, modification with the biomolecules, stability studies. Chapter 3 decribes fundamental studies of the electrodeposition of the functionalised Au nanoparticles on the electrode surface. Chapter 4 describes the application of the electrodeposition of the protein functionalised Au nanoparticles for the creation of biosensor arrays. Chapter 5 describes the selective immobilization of biomolecules through electrochemical deprotection of electroactive self-assembled monolayers. Chapter 6 describes the synthesis, characterization and selective immobilization of HRP functionalized 4,4-bipyridyl derivatives. Chapter 7 describes the selective microscale protein patterning of two oxidases on an IDE array through photolithography. Finally chapter 8 summarizes the conclusions and the future work.
Yucel, Deniz. "Construction Of A Choline Oxidase Biosensor". Master's thesis, METU, 2003. http://etd.lib.metu.edu.tr/upload/4/1083021/index.pdf.
Pełny tekst źródła5 µ
M minimum detection limit. The response of the sensor decreased linearly upon successive measurements.
Senyurt, Ozge. "Development Of Paper Type Tyrosinase Biosensor". Master's thesis, METU, 2008. http://etd.lib.metu.edu.tr/upload/3/12609542/index.pdf.
Pełny tekst źródłaC when compared to at the beginning response.
Khetani, Altaf. "Photonic crystal fiber as a biosensor". Thesis, University of Ottawa (Canada), 2008. http://hdl.handle.net/10393/27596.
Pełny tekst źródłaWeston, D. G. "Molecular engineering of the biosensor interface". Thesis, Cranfield University, 1999. http://dspace.lib.cranfield.ac.uk/handle/1826/3295.
Pełny tekst źródłaK'Owino, Isaac Odhiambo. "Metal-enhanced electrochemical biosensor & nanoremediation". Diss., Online access via UMI:, 2006.
Znajdź pełny tekst źródłaWatts, Helen. "Cell detection by an optical biosensor". Thesis, University of Cambridge, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.339626.
Pełny tekst źródłaBacke, Kalle. "Functionalization of graphene for biosensor-applications". Thesis, Uppsala universitet, Oorganisk kemi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-238249.
Pełny tekst źródłaForeman, Pamela Louise. "Spectroscopic characterisation of electrochemical biosensor interfaces". Thesis, University of Glasgow, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284728.
Pełny tekst źródłaGriffith, Alun Wyn. "Applications of microfabrication in biosensor technology". Thesis, University of Glasgow, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.361768.
Pełny tekst źródłaJaffari, Samarah A. "A potentially implantable amperometric glucose biosensor". Thesis, Cranfield University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.282439.
Pełny tekst źródłaDu, Yao. "Particle-modified surface plasmon resonance biosensor". Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/289388.
Pełny tekst źródłaKato, Gerard Bamuturaki. "Impedance measurement platform for impedimetric biosensor". Thesis, Massachusetts Institute of Technology, 2015. http://hdl.handle.net/1721.1/100605.
Pełny tekst źródłaThis electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Title as it appears in MIT Commencement Exercises program, June 5, 2015: Portable impedimetric biosensor. Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references (pages 64-65).
Measuring proteins in blood is particularly common such as in PSA, to determine prostate function and in many other bio-applications. Today this process is inconveniencing in that it requires a lot of blood from the patients for tests to be made. Furthermore it is time consuming and expensive since samples are transferred to a central lab where tests are carried out on optical assays. Using electrical read out methods several measurements can be multiplexed and a differential measurements made. With a differential measurement the precision of the system is improved by cancelling out common mode bio-chemical noise. The multiplexed measurement enables measurement of several analytes. Using the embedded system MAX32600, an electrical impedance meter was designed that measures three impedances simultaneously with accuracy range of up-to 1% and precision of 0.2% of the actual impedance measured from an Impedance analyzer.
by Gerard Bamuturaki Kato.
M. Eng.
Loechel, Claudia. "Designs of an enzymatic trimethylamine biosensor". Thesis, University of Cambridge, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.620528.
Pełny tekst źródłaZhang, Yangyang. "A functionalised aptamer electrochemical biosensor platform". Thesis, Imperial College London, 2011. http://hdl.handle.net/10044/1/6438.
Pełny tekst źródłaBurwell, Gregory. "Epitaxial graphene growth and biosensor fabrication". Thesis, Swansea University, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678626.
Pełny tekst źródłaGregory, Jarod. "Microbial Detection in Surface Waters: Creating a Remote-Controlled Mobile Microbial Biosensor". University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1439301079.
Pełny tekst źródłaBusse, Stefan. "Untersuchung molekularer Erkennungsreaktionen mit einem integriert-optischen Mach-Zehnder-Interferometer". [S.l. : s.n.], 2000. http://ArchiMeD.uni-mainz.de/pub/2000/0017/diss.pdf.
Pełny tekst źródłaNikolaides, Michael G. "Silicon-on-insulator based thin-film resistor for the detection of biomolecular interactions". [S.l. : s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=972317392.
Pełny tekst źródłaStepper, Christoph. "Entwurf, Herstellung und Charakterisierung von Biosensorchips". [S.l. : s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=974900494.
Pełny tekst źródłaDiéguez, Moure Lorena. "Optical grating coupler biosensor and biomedical applications". Doctoral thesis, Universitat de Barcelona, 2012. http://hdl.handle.net/10803/101149.
Pełny tekst źródłaEsta tesis consiste en el diseño, fabricación y test de un Biosensor Óptico basado en redes de difracción y sus aplicaciones en biomedicina. Los biosensores ópticos son dispositivos que detectan interacciones biomoleculares específicas mediante un transductor óptico. Exhiben alta sensibilidad, alta estabilidad mecánica, son inmunes a las interferencias electromagnéticas y permiten medidas no destructivas. En los Biosensores Ópticos por Onda Evanescente un modo guiado se propaga a lo largo de la guía de ondas mientras que la onda evanescente interactúa con la superficie del sensor, reconociendo cualquier interacción biomolecular que provoque una modificación en el índice de refracción efectivo de la guía óptica. En este caso, la inserción de luz láser en la guía óptica se produce con ayuda de una red de difracción grabada en la superficie del sensor. Para un ángulo muy preciso se excita un modo guiado. Como consecuencia de las reacciones en la superficie se produce un cambio en el ángulo de acoplo. La medida en tiempo real del ángulo de acoplo, en función de la actividad bioquímica en la superficie es la base de este tipo de biosensor óptico. El objetivo es fabricar sensores de bajo coste en polímero y también en distintos materiales que permitan calibrar otras técnicas. Otro objetivo de esta tesis es la calibración de los sensores y de las distintas soluciones buffer comúnmente usadas en biosensado. Como aplicación, se ha usado un equipo comercial (Optical Waveguide Lightomode Spectroscopy, OWLS, MicroVacuum) para estudiar, mediante control electroquímico, el crecimiento y la liberación de multicapas de PLL/DNA para aplicaciones en administración de fármacos. También se ha usado el OWLS para optimizar la inmovilización de receptores olfativos en un dispositivo biosensor para el desarrollo de una nariz bioelectrónica.
Samudrala, Pavan Kumar. "Alumina waveguide characterization and SPARROW biosensor modeling". Morgantown, W. Va. : [West Virginia University Libraries], 2006. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=4841.
Pełny tekst źródłaTitle from document title page. Document formatted into pages; contains vii, 85 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 70-72).
Wingqvist, Gunilla. "Thin Film Electroacoustic Devices for Biosensor Applications". Doctoral thesis, Uppsala universitet, Fasta tillståndets elektronik, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-89424.
Pełny tekst źródławisenet
Zhao, Min Chemistry Faculty of Science UNSW. "A fill and flow channel enzyme biosensor". Awarded by:University of New South Wales, 2004. http://handle.unsw.edu.au/1959.4/38333.
Pełny tekst źródłaPoloju, Praneetha. "Fabrication and functional analysis of SPARROW biosensor". Morgantown, W. Va. : [West Virginia University Libraries], 2007. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=5374.
Pełny tekst źródłaTitle from document title page. Document formatted into pages; contains viii, 90 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 74-76).
Ramanathan, Madhumati Simonian Aleksandr L. "Array biosensor for the detection of organophosphates". Auburn, Ala., 2006. http://repo.lib.auburn.edu/2006%20Summer/Theses/RAMANATHAN_MADHUMATI_51.pdf.
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