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1

Râpă, Maria, Laura Mihaela Stefan, Traian Zaharescu, Ana-Maria Seciu, Anca Andreea Țurcanu, Ecaterina Matei, Andra Mihaela Predescu, Iulian Antoniac i Cristian Predescu. "Development of Bionanocomposites Based on PLA, Collagen and AgNPs and Characterization of Their Stability and In Vitro Biocompatibility". Applied Sciences 10, nr 7 (26.03.2020): 2265. http://dx.doi.org/10.3390/app10072265.

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Bionanocomposites including poly(lactic acid) (PLA), collagen, and silver nanoparticles (AgNPs) were prepared as biocompatible and stable films. Thermal properties of the PLA-based bionanocomposites indicated an increase in the crystallinity of PLA plasticized due to a small quantity of AgNPs. The results on the stability study indicate the promising contribution of the AgNPs on the durability of PLA-based bionanocomposites. In vitro biocompatibility conducted on the mouse fibroblast cell line NCTC, clone 929, using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay showed high values of cell viability (>80%) after cell cultivation in the presence of bionanocomposite formulations for 48 h, while the percentages of lactate dehydrogenase (LDH) released in the culture medium were reduced (<15%), indicating no damages of the cell membranes. In addition, cell cycle analysis assessed by flow cytometry indicated that all tested bionanocomposites did not affect cell proliferation and maintained the normal growth rate of cells. The obtained results recommend the potential use of PLA-based bionanocomposites for biomedical coatings.
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Darder, Margarita, Jing He, Laurent Charlet, Eduardo Ruiz-Hitzky i Pilar Aranda. "Gentamicin-Montmorillonite Intercalation Compounds as an Active Component of Hydroxypropylmethylcellulose Bionanocomposite Films with Antimicrobial Properties". Clays and Clay Minerals 69, nr 5 (październik 2021): 576–88. http://dx.doi.org/10.1007/s42860-021-00156-3.

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AbstractThe present study introduces an overview of gentamicin-clay mineral systems for applications in biomedicine and then focuses on the development of a series of gentamicin/clay hybrid materials to be used as the bioactive phase of hydroxypropylmethylcellulose (HPMC) to produce bionanocomposite membranes possessing antimicrobial activity of interest in wound-dressing applications. Gentamicin (Gt) was adsorbed from aqueous solutions into a montmorillonite (Cloisite®-Na+) to produce intercalation compounds with tunable content of the antibiotic. The hybrids were characterized by CHN chemical analysis, energy-dispersive X-ray analysis, X-ray diffraction, Fourier-transform infrared spectroscopy, and thermogravimetric analysis, confirming the intercalation of Gt by an ion-exchange mechanism. The release of Gt from the hybrids was tested in water and in buffer solution to check their stability. Hybrids with various amounts of Gt were incorporated into a HPMC matrix at various loadings and processed as films by the casting method. The resulting Gt-clay/HPMC bionanocomposites were characterized by means of field-emission scanning electron microscopy, and were also evaluated for their water-adsorption and mechanical properties to confirm their suitability for wound-dressing applications. The antimicrobial activity of the bionanocomposite films was tested in vitro toward various microorganisms (Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecium, Acinetobacter baumannii, and Klebsiella pneumonia), showing a complete bacterial reduction even in films with small Gt contents.
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Ahmadizadegan, Hashem, i Sheida Esmaielzadeh. "Gas transport membranes based on novel optically active polyester/cellulose/ZnO bionanocomposite membranes". Journal of the Iranian Chemical Society 15, nr 4 (26.12.2017): 799–811. http://dx.doi.org/10.1007/s13738-017-1279-6.

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Ahmadizadegan, Hashem, i Sheida Esmaielzadeh. "Preparation and application of novel bionanocomposite green membranes for gas separation". Polymer Bulletin 76, nr 10 (24.11.2018): 4903–27. http://dx.doi.org/10.1007/s00289-018-2621-6.

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Kushwaha, Omkar S., C. V. Avadhani i R. P. Singh. "Preparation and characterization of self-photostabilizing UV-durable bionanocomposite membranes for outdoor applications". Carbohydrate Polymers 123 (czerwiec 2015): 164–73. http://dx.doi.org/10.1016/j.carbpol.2014.12.062.

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Algar, Itxaso, Clara Garcia-Astrain, Alba Gonzalez, Loli Martin, Nagore Gabilondo, Aloña Retegi i Arantxa Eceiza. "Improved Permeability Properties for Bacterial Cellulose/Montmorillonite Hybrid Bionanocomposite Membranes by In-Situ Assembling". Journal of Renewable Materials 4, nr 1 (13.02.2016): 57–65. http://dx.doi.org/10.7569/jrm.2015.634124.

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Zanella, Gabrielle Susan, Daniela Becker, Andrea Lima Santos Schneider, Ana Paula Testa Pezzin, Denise Abatti Kasper Silva i André Lourenço Nogueira. "PLLA–silver nanoparticles bionanocomposite membranes: Preparation, antibacterial activity, and in vitro hydrolytic degradation assessment". Journal of Applied Polymer Science 136, nr 39 (22.05.2019): 47998. http://dx.doi.org/10.1002/app.47998.

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Das, Gautam, Bang Ju Park i Hyon Hee Yoon. "A bionanocomposite based on 1,4-diazabicyclo-[2.2.2]-octane cellulose nanofiber cross-linked-quaternary polysulfone as an anion conducting membrane". Journal of Materials Chemistry A 4, nr 40 (2016): 15554–64. http://dx.doi.org/10.1039/c6ta05611c.

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Esmaielzadeh, Sheida, i Hashem Ahmadizadegan. "Construction of proton exchange membranes under ultrasonic irradiation based on novel fluorine functionalizing sulfonated polybenzimidazole/cellulose/silica bionanocomposite". Ultrasonics Sonochemistry 41 (marzec 2018): 641–50. http://dx.doi.org/10.1016/j.ultsonch.2017.10.029.

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Mouro, Cláudia, Raul Fangueiro i Isabel C. Gouveia. "Preparation and Characterization of Electrospun Double-layered Nanocomposites Membranes as a Carrier for Centella asiatica (L.)". Polymers 12, nr 11 (11.11.2020): 2653. http://dx.doi.org/10.3390/polym12112653.

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A wide range of naturally derived and synthetic biodegradable and biocompatible polymers are today regarded as promising materials for improving skin regeneration. Alongside this, these materials have been explored in conjunction with different types of antimicrobial and bioactive agents, especially natural-derived compounds, to enhance their biological properties. Herein, a double-layered nanocomposite dressing membrane was fabricated with two distinct layers. A bottom layer from Chitosan-Sodium tripolyphosphate (CS-TPP) and Poly(vinyl alcohol) (PVA) containing Centella asiatica (L.) (CA) was electrospun directly over a Polycaprolactone (PCL) layer to improve the biologic performance of the electrospun nanofibers. In turn, the PCL layer was designed to provide mechanical support to the damaged tissue. The results revealed that the produced double-layered nanocomposite membrane closely resembles the mechanical, porosity, and wettability features required for skin tissue engineering. On the other hand, the in vitro drug release profile of the PCL/PVA_CS-TPP containing CA exhibited a controlled release for 10 days. Moreover, the PVA_CS-TPP_CA’s bottom layer displayed the highest antibacterial activity against Staphylococcus aureus (S. aureus) (99.96 ± 6.04%) and Pseudomonas aeruginosa (P. aeruginosa) (99.94 ± 0.67%), which is responsible for avoiding bacterial penetration while endowing bioactive properties. Finally, the 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay showed that this nanocomposite membrane was not cytotoxic for normal human dermal fibroblasts (NHDF) cells. Therefore, these findings suggest the potential use of the double-layered PCL/PVA_CS-TPP_CA as an efficient bionanocomposite dressing material.
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Kim, Insoo, Karthika Viswanathan, Gopinath Kasi, Kambiz Sadeghi, Sarinthip Thanakkasaranee i Jongchul Seo. "Poly(Lactic Acid)/ZnO Bionanocomposite Films with Positively Charged ZnO as Potential Antimicrobial Food Packaging Materials". Polymers 11, nr 9 (30.08.2019): 1427. http://dx.doi.org/10.3390/polym11091427.

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A series of PLA/ZnO bionanocomposite films were prepared by introducing positively surface charged zinc oxide nanoparticles (ZnO NPs) into biodegradable poly(lactic acid) (PLA) by the solvent casting method, and their physical properties and antibacterial activities were evaluated. The physical properties and antibacterial efficiencies of the bionanocomposite films were strongly dependent on the ZnO NPs content. The bionanocomposite films with over 3% ZnO NPs exhibited a rough surface, poor dispersion, hard agglomerates, and voids, leading to a reduction in the crystallinity and morphological defects. With the increasing ZnO NPs content, the thermal stability and barrier properties of the PLA/ZnO bionanocomposite films were decreased while their hydrophobicity increased. The bionanocomposite films showed appreciable antimicrobial activity against Staphylococcus aureus and Escherichia coli. Especially, the films with over 3% of ZnO NPs exhibited a complete growth inhibition of E. coli. The strong interactions between the positively charged surface ZnO NPs and negatively charged surface of the bacterial membrane led to the production of reactive oxygen species (ROS) and eventually bacterial cell death. Consequently, these PLA/ZnO bionanocomposite films can potentially be used as a food packaging material with excellent UV protective and antibacterial properties.
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Uyen, Nguyen Thai Ngoc. "PREPARATION OF BIO-NANOCOMPOSITE MEMBRANE FOR METHYLENE BLUE ADSORPTION". Vietnam Journal of Science and Technology 56, nr 2A (21.06.2018): 174–78. http://dx.doi.org/10.15625/2525-2518/56/2a/12680.

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In this study, the bio-nanocomposite composed of chitosan and nanoclay was prepared by solution intercalation method. The membrane was subsequently fabricated by dry/wet phase separation technique. The structure of bio-nanocomposite was characterized by Fourier-transform infrared spectroscopy (FT-IR) and X-ray diffraction (XRD) and scanning electron microscope (SEM). The membrane was applied to adsorb methylene blue (MB) for water treatment. The adsorption of MB was monitored through UV-Vis spectroscopy. The results showed that bionanocomposite membrane could adsorb MB up to 97.9 % in 150 min. The MB adsorption of bionanocomposite membrane was 234 times as high as the adsorption of the conventional chitosan films that is promising for environmental applications.
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Gebreyohannes, Abaynesh Yihdego, Rosalinda Mazzei, Teresa Poerio, Pierre Aimar, Ivo F. J. Vankelecom i Lidietta Giorno. "Pectinases immobilization on magnetic nanoparticles and their anti-fouling performance in a biocatalytic membrane reactor". RSC Advances 6, nr 101 (2016): 98737–47. http://dx.doi.org/10.1039/c6ra20455d.

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Galateanu, Bianca, Mihaela-Cristina Bunea, Paul Stanescu, Eugenia Vasile, Angela Casarica, Horia Iovu, Anca Hermenean, Catalin Zaharia i Marieta Costache. "In VitroStudies of Bacterial Cellulose and Magnetic Nanoparticles Smart Nanocomposites for Efficient Chronic Wounds Healing". Stem Cells International 2015 (2015): 1–10. http://dx.doi.org/10.1155/2015/195096.

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The quality of life of patients with chronic wounds can be extremely poor and, therefore, over the past decades, great efforts have been made to develop efficient strategies to improve the healing process and the social impact associated with these conditions. Cell based therapy, as a modern tissue engineering strategy, involves the design of 3D cell-scaffold bioconstructs obtained by preseeding drug loaded scaffolds with undifferentiated cells in order to achievein situfunctionalde novotissue. This paper reports on the development of bionanocomposites based on bacterial cellulose and magnetic nanoparticles (magnetite) for efficient chronic wounds healing. Composites were obtained directly in the cellulose bacterial culture medium by dispersing various amounts of magnetite nanoparticles during the biosynthesis process. After purification and drying, the membranes were characterized by Raman spectroscopy and X-ray diffraction to reveal the presence of magnetite within the bacterial cellulose matrix. Morphological investigation was employed through SEM and TEM analyses on bionanocomposites. The biocompatibility of these innovative materials was studied in relation to human adipose derived stem cells in terms of cellular morphology, viability, and proliferation as well as scaffolds cytotoxic potential.
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Lo Dico, Giulia, Bernd Wicklein, Lorenzo Lisuzzo, Giuseppe Lazzara, Pilar Aranda i Eduardo Ruiz-Hitzky. "Multicomponent bionanocomposites based on clay nanoarchitectures for electrochemical devices". Beilstein Journal of Nanotechnology 10 (25.06.2019): 1303–15. http://dx.doi.org/10.3762/bjnano.10.129.

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Based on the unique ability of defibrillated sepiolite (SEP) to form stable and homogeneous colloidal dispersions of diverse types of nanoparticles in aqueous media under ultrasonication, multicomponent conductive nanoarchitectured materials integrating halloysite nanotubes (HNTs), graphene nanoplatelets (GNPs) and chitosan (CHI) have been developed. The resulting nanohybrid suspensions could be easily formed into films or foams, where each individual component plays a critical role in the biocomposite: HNTs act as nanocontainers for bioactive species, GNPs provide electrical conductivity (enhanced by doping with MWCNTs) and, the CHI polymer matrix introduces mechanical and membrane properties that are of key significance for the development of electrochemical devices. The resulting characteristics allow for a possible application of these active elements as integrated multicomponent materials for advanced electrochemical devices such as biosensors and enzymatic biofuel cells. This strategy can be regarded as an “a la carte” menu, where the selection of the nanocomponents exhibiting different properties will determine a functional set of predetermined utility with SEP maintaining stable colloidal dispersions of different nanoparticles and polymers in water.
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Xu, Xu Fan. "Preparation and In Vitro Degradation of PLGA/HA Composite Fiber Scaffolds by Electrospinning". Advanced Materials Research 591-593 (listopad 2012): 982–88. http://dx.doi.org/10.4028/www.scientific.net/amr.591-593.982.

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The preparation of scaffolds consisted of a polymer composites with inorganic materials has received extensive attention in the field of tissue engineering recently.Electrospinning is a good method to obtain nano-scaled fibers from polymer solutions. In this paper ,we successfully prepared nanofibers of poly(lactide-co-glycolde) (PLGA)/hydroxyapatite(HA)by electrospinning.Their structure morphology and degradation behaviors were studied.The in vitro degradation of PLGA/ HA composite membranes was examined for up to 16 weeks in phosphate-buffered saline (PBS, pH 7.4) at 37°C. The results indicated that the surface of hybrid fibers was much coarser because of the introduction of HA nano-particles. The alkaline HA nano-particles inhibited the self-catalysis of PLGA during the degradation and slowed down the degradation rates of hybrid fibers.The introduction of hydroxyapatite component changed the hydrophilic/hydrophobic balance and, thus, influenced degradation behavior and mechanical properties of the composite membranes during degradation. The preliminary results show that comprehensive properties are well better on the hybrid scaffolds than pure scaffolds and PLGA/ HA bionanocomposites have the potential in tissue regeneration applications.
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Cui, Jie, Xiao Yu, Yihong Shen, Binbin Sun, Wanxin Guo, Mingyue Liu, Yujie Chen i in. "Electrospinning Inorganic Nanomaterials to Fabricate Bionanocomposites for Soft and Hard Tissue Repair". Nanomaterials 13, nr 1 (2.01.2023): 204. http://dx.doi.org/10.3390/nano13010204.

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Tissue engineering (TE) has attracted the widespread attention of the research community as a method of producing patient-specific tissue constructs for the repair and replacement of injured tissues. To date, different types of scaffold materials have been developed for various tissues and organs. The choice of scaffold material should take into consideration whether the mechanical properties, biodegradability, biocompatibility, and bioresorbability meet the physiological properties of the tissues. Owing to their broad range of physico-chemical properties, inorganic materials can induce a series of biological responses as scaffold fillers, which render them a good alternative to scaffold materials for tissue engineering (TE). While it is of worth to further explore mechanistic insight into the use of inorganic nanomaterials for tissue repair, in this review, we mainly focused on the utilization forms and strategies for fabricating electrospun membranes containing inorganic components based on electrospinning technology. A particular emphasis has been placed on the biological advantages of incorporating inorganic materials along with organic materials as scaffold constituents for tissue repair. As well as widely exploited natural and synthetic polymers, inorganic nanomaterials offer an enticing platform to further modulate the properties of composite scaffolds, which may help further broaden the application prospect of scaffolds for TE.
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Ahmadizadegan, Hashem, Sheida Esmaielzadeh, Mahdi Ranjbar, Zahra Marzban i Fatemeh Ghavas. "Synthesis and characterization of polyester bionanocomposite membrane with ultrasonic irradiation process for gas permeation and antibacterial activity". Ultrasonics Sonochemistry 41 (marzec 2018): 538–50. http://dx.doi.org/10.1016/j.ultsonch.2017.10.020.

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Esmaeilzade, Banafshe, Sheida Esmaielzadeh i Hashem Ahmadizadegan. "Ultrasonic irradiation to modify the functionalized bionanocomposite in sulfonated polybenzimidazole membrane for fuel cells applications and antibacterial activity". Ultrasonics Sonochemistry 42 (kwiecień 2018): 260–70. http://dx.doi.org/10.1016/j.ultsonch.2017.11.032.

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Ahmadizadegan, Hashem, Mahdi Ranjbar i Sheida Esmaielzadeh. "Synthesis and characterization of green membranes polyimide/titania bionanocomposites containing amino acid and benzimidazole moieties for gas transport properties". Polymer Engineering & Science 58, nr 9 (4.11.2017): 1666–77. http://dx.doi.org/10.1002/pen.24757.

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Ekambaram, Kavitha, i Mohan Doraisamy. "Surface modification of PVDF nanofiltration membrane using Carboxymethylchitosan-Zinc oxide bionanocomposite for the removal of inorganic salts and humic acid". Colloids and Surfaces A: Physicochemical and Engineering Aspects 525 (lipiec 2017): 49–63. http://dx.doi.org/10.1016/j.colsurfa.2017.04.071.

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Li, Yuyao, Haidan Wang, Yingying Li, Huicui Wen, Haoran Huang, Zitong Huang, Wenbei Situ i Xianliang Song. "Preparation of nano-Ag-Bi2WO6–TiO2/starch bionanocomposite membranes and mechanism of enhancing visible light degradation of ethylene". Ceramics International, lipiec 2023. http://dx.doi.org/10.1016/j.ceramint.2023.06.298.

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Dumitriu, Raluca Petronela, Liviu Sacarescu, Doina Macocinschi, Daniela Filip i Cornelia Vasile. "Effect of silver nanoparticles on the dispersion, rheological properties and morphological aspect of solvent cast polyurethane/biopolymers bionanocomposite membranes". Journal of Adhesion Science and Technology, 30.11.2015, 1–11. http://dx.doi.org/10.1080/01694243.2015.1111287.

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Radwan, Mahmoud, Mahmoud A. El-Sharkawy, Mohammed A. Negm, Amaal Mohammadein, Jamila S. Al Malki, Asma W. Al-Thomali, Ahmed M. Mohamed, Shahd Yassir i Mansour A. E. Bashar. "Dual effect of dietary seaweed of extract nanoparticles (GNS) with bionanocomposite cellulose acetate membranes (CA/bio-AgNps) on growth performance and health status of the Nile tilapia (Oreochromis niloticus): Specification on feed utilization, immune system, and antiparasitic action". Frontiers in Marine Science 9 (27.10.2022). http://dx.doi.org/10.3389/fmars.2022.1008397.

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Seaweed draws a lot of attention for its vital role in aquaculture as it contains beneficial biological compounds that undoubtedly might help in the development of this field. The current study sheds light on the potential efficiency of dietary supplements of Grateloupia acuminata and G. doryphore (Halymeniaceae) nanoparticles (GNS) at different levels with bionanocomposite cellulose acetate membranes (CA/bio-AgNps) on improved growth performance, digestive enzyme activity, immunity, antioxidative, resistance against infectious pathogens, and characterization of water quality treated with CA/bio-AgNps that is used in rearing Nile tilapia (Oreochromis niloticus). Four concentrations (0.1, 0.25, 0.5, and 1.0 ml/L) of GNS extract were tested as potential anti-bacterial and for the efficacy of being parasitic. Fish with an average weight (24.46 ± 0. 50 g) were apportioned into six experimental groups (T0, T1, T2, T3, T4, and T5) represented as 0.0%, 0.0%, 0.1%, 0.25%, 0.5%, and 1.0% GNS in diets with CA/bio-AgNps, respectively. Injection of fish with Aeromonas hydrophila was performed at the end of the trial. Chemical and bacteriological water indices significantly showed improvement after being treated with CA/bio-AgNps than the control group. Growth, carcass composition, digestive enzyme, and hematological and biochemical indices were significantly noticed positive (p&lt; 0.05), especially T4 and T5, than the control group. In parallel, a significant improvement was noticed in serum lysozyme, total immunoglobulin, complement C3, antioxidative enzyme, and the relative expression of hepatic and inflammatory genes with an increased level of GNS (p&lt; 0.05) are upregulated than the control group. Remarkably, GNS-supplemented diets and extracts provided positive efficacy against A. hydrophila with a decreased percentage of fish mortality, besides efficacy on antibacterial strains and Cichlidogyrus tilapiae, respectively. To sum up, the seaweed extract with CA/bio-AgNps resulted in better growth performance of fish, antipathogenic effect, and health status. Furthermore, CA/bio-AgNps were vital in improving water characteristics. They should be studied and applied more in the future.
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Taşkın Çakıcı, Gülşen. "Nano TiO2-doped sodium alginate/hydroxypropyl methylcellulose synthesis of bionanocomposite membrane and its use in controlled release of anti-cancer drug 5-fluorouracil". Polymer Bulletin, 12.01.2023. http://dx.doi.org/10.1007/s00289-023-04674-z.

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Baláž, Matej, Elena V. Boldyreva, Dmitry Rybin, Stefan Pavlović, Daily Rodríguez-Padrón, Tihana Mudrinić i Rafael Luque. "State-of-the-Art of Eggshell Waste in Materials Science: Recent Advances in Catalysis, Pharmaceutical Applications, and Mechanochemistry". Frontiers in Bioengineering and Biotechnology 8 (27.01.2021). http://dx.doi.org/10.3389/fbioe.2020.612567.

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Eggshell waste is among the most abundant waste materials coming from food processing technologies. Despite the unique properties that both its components (eggshell, ES, and eggshell membrane, ESM) possess, it is very often discarded without further use. This review article aims to summarize the recent reports utilizing eggshell waste for very diverse purposes, stressing the need to use a mechanochemical approach to broaden its applications. The most studied field with regards to the potential use of eggshell waste is catalysis. Upon proper treatment, it can be used for turning waste oils into biodiesel and moreover, the catalytic effect of eggshell-based material in organic synthesis is also very beneficial. In inorganic chemistry, the eggshell membrane is very often used as a templating agent for nanoparticles production. Such composites are suitable for application in photocatalysis. These bionanocomposites are also capable of heavy metal ions reduction and can be also used for the ozonation process. The eggshell and its membrane are applicable in electrochemistry as well. Due to the high protein content and the presence of functional groups on the surface, ESM can be easily converted to a high-performance electrode material. Finally, both ES and ESM are suitable for medical applications, as the former can be used as an inexpensive Ca2+ source for the development of medications, particles for drug delivery, organic matrix/mineral nanocomposites as potential tissue scaffolds, food supplements and the latter for the treatment of joint diseases, in reparative medicine and vascular graft producing. For the majority of the above-mentioned applications, the pretreatment of the eggshell waste is necessary. Among other options, the mechanochemical pretreatment has found an inevitable place. Since the publication of the last review paper devoted to the mechanochemical treatment of eggshell waste, a few new works have appeared, which are reviewed here to underline the sustainable character of the proposed methodology. The mechanochemical treatment of eggshell is capable of producing the nanoscale material which can be further used for bioceramics synthesis, dehalogenation processes, wastewater treatment, preparation of hydrophobic filters, lithium-ion batteries, dental materials, and in the building industry as cement.
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Kamari, Soran, i Afsaneh Shahbazi. "High–performance nanofiltration membrane blended by Fe3O4@SiO2–CS bionanocomposite for efficient simultaneous rejection of salts/heavy metals ions/dyes with high permeability, retention increase and fouling decline". Chemical Engineering Journal, grudzień 2020, 127930. http://dx.doi.org/10.1016/j.cej.2020.127930.

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