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Artykuły w czasopismach na temat "Biomineralization/calcification"

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Kazama, Junichiro James, Norio Amizuka i Masafumi Fukagawa. "Ectopic Calcification as Abnormal Biomineralization". Therapeutic Apheresis and Dialysis 10 (grudzień 2006): S34—S38. http://dx.doi.org/10.1111/j.1744-9987.2006.00438.x.

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Pawlikowski, Maciej. "Centers of Human Tissue Biomineralization (Calcification)". Cardiology and Cardiovascular Medicine 01, nr 06 (2017): 252–61. http://dx.doi.org/10.26502/fccm.92920030.

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Yoshida, Naoto. "Simple Assessing of Calcification Catalyzed by Thermophilic Bacteria". European Journal of Theoretical and Applied Sciences 1, nr 5 (1.09.2023): 786–89. http://dx.doi.org/10.59324/ejtas.2023.1(5).65.

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Several bacterial species have been found to involve the biomineralization phenomenon promoted by them. The formation of calcium carbonate mineral (calcification) is most abundant phenomena as biomineralization by bacteria. Here we introduce the simple assessing method of calcification catalyzed by thermophilic bacteria. To obtain the fresh biomass of thermophilic bacterium, the thermophilic bacteria was cultured on conventional nutrient agar medium at 60˚C. Fresh biomass of bacteria is simply placed on calcite promoting hydrogel surface, and incubated at 60˚C. After incubation for 24 to 72 h, a number of single crystals can be found in the biomass. This method provides simple assessing for screening of calcification upon thermophilic bacteria.
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Yarra, Tejaswi, Mark Blaxter i Melody S. Clark. "A Bivalve Biomineralization Toolbox". Molecular Biology and Evolution 38, nr 9 (20.05.2021): 4043–55. http://dx.doi.org/10.1093/molbev/msab153.

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Abstract Mollusc shells are a result of the deposition of crystalline and amorphous calcite catalyzed by enzymes and shell matrix proteins (SMP). Developing a detailed understanding of bivalve mollusc biomineralization pathways is complicated not only by the multiplicity of shell forms and microstructures in this class, but also by the evolution of associated proteins by domain co-option and domain shuffling. In spite of this, a minimal biomineralization toolbox comprising proteins and protein domains critical for shell production across species has been identified. Using a matched pair design to reduce experimental noise from inter-individual variation, combined with damage-repair experiments and a database of biomineralization SMPs derived from published works, proteins were identified that are likely to be involved in shell calcification. Eighteen new, shared proteins likely to be involved in the processes related to the calcification of shells were identified by the analysis of genes expressed during repair in Crassostrea gigas, Mytilus edulis, and Pecten maximus. Genes involved in ion transport were also identified as potentially involved in calcification either via the maintenance of cell acid–base balance or transport of critical ions to the extrapallial space, the site of shell assembly. These data expand the number of candidate biomineralization proteins in bivalve molluscs for future functional studies and define a minimal functional protein domain set required to produce solid microstructures from soluble calcium carbonate. This is important for understanding molluscan shell evolution, the likely impacts of environmental change on biomineralization processes, materials science, and biomimicry research.
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Xu, Chen Yang, Qi Wang, Hong Yu Ban i Wei Xu. "Rapid Deposition of Hydroxyapatite on Mg-Alloy by Biomineralization Method". Advanced Materials Research 413 (grudzień 2011): 160–65. http://dx.doi.org/10.4028/www.scientific.net/amr.413.160.

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Rapid deposition of hydroxyapatite on Mg-alloy in concentrated simulated body fluid (5×SBF) and modified simulated body fluid (m-SBF) was investigated. By biomineralization method, hydroxyapatite coating was deposited on Mg-alloy with pre-calcification treatment. Scanning electron microscope (SEM), energy disperse spectroscopy (EDS) and X-ray diffraction instrument (XRD) were applied to analyze the deposition product of biomineralization and the related mechanism. The results showed that pre-calcification treatment on Mg-alloy can lead to a quite rapid deposition of hydroxyapatite. Ionic concentrations in SBF solutions affected the structure of hydroxyapatite greatly. A homogeneous plate-like apatite coating was induced on Mg alloy sample in m-SBF solution which is promising for the future practice.
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Denysenko, Anastasiya P., i Roman A. Moskalenko. "BIBLIOMETRIC ANALYSIS OF THE SCIENTIFIC LITERATURE ON MENINGIOMAS WITH CALCIFICATION". Eastern Ukrainian Medical Journal 10, nr 1 (2022): 98–108. http://dx.doi.org/10.21272/eumj.2022;10(1):98-108.

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Meningiomas are the most common non-glial tumours of the central nervous system characterized by pathological biomineralization. The work aimed to conduct bibliometric analysis and systematize data on the prevalence, etiology, morphology and main trends in the study of meningiomas with calcification. The authors searched for information on meningiomas in electronic databases such as PubMed, Scopus, Web of Science and Google Scholar for the past 25 years by the key terms such as meningiomas, calcifications, and psammoma bodies. For bibliometric analysis, the authors used an online platform to monitor and analyze international research using visualization tools and modern citation metrics SciVal (Scopus) and a tool for building and visualizing bibliometric networks VOSviewer. Pathological biomineralization is manifested through the formation of psammoma bodies, and the main mineral component is calcium hydroxyapatite. Although calcification is likely to play a protective role and be a favourable prognostic feature, it should be considered when choosing surgical tactics. There is also the problem of closing the defects of the dura mater with the help of biological and synthetic transplants. According to the bibliometric analysis of scientific literature on meningiomas and the phenomena of pathological biomineralization in them, we found that the number of publications on this topic had increased significantly over the past five years, the leading countries of origin are the United States, Japan and China. When researching the array of Scopus database publications using SciVal tools, the problem of meningioma calcification was divided into 61 topics and 24 thematic clusters, the vast majority of which belonged to medicine and biology and materials science. According to the results of bibliometric analysis of 678 publications in the Scopus database by keywords "calcification" and "meningioma", they can be divided into seven thematic clusters and four chronological stages. Despite the prevalence of meningioma calcification, there is currently no fundamental idea of ​​the etiology and pathogenesis of this process. Studying the morphological features of meningiomas with calcification can help improve the diagnosis and treatment of the central nervous system tumours.
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Basso, Daniela, Giulia Piazza i Valentina Alice Bracchi. "Calcification traits for cryptic species identification: Insights into coralline biomineralization". PLOS ONE 17, nr 10 (3.10.2022): e0273505. http://dx.doi.org/10.1371/journal.pone.0273505.

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Calcareous red algae are foundation species and ecosystem engineers with a global distribution. The principles governing their calcification pathways are still debated and the morphological characters are frequently unreliable for species segregation, as shown by molecular genetics. The recent description of the new species Lithophyllum pseudoracemus, previously undetected and morphologically confused with Lithophyllum racemus, offered a challenging opportunity to test the effectiveness of microanatomy and ultrastructural calcification traits as tools for the identification of these two species, for integrative taxonomy. High resolution SEM images of molecularly identified samples showed that the different size of the perithallial cells and the features of the asexual conceptacle chambers may contribute to the separation of the two species. The two species share the same crystallite morphology in the primary and secondary cell-wall calcification, as previously described in other species belonging to the same clade. However, the perithallial secondary calcification was significantly thicker in L. racemus than in L. pseudoracemus. We described a granular calcified layer in the innermost part of the cell wall, as a putative precursor phase in the biomineralization and formation of the secondary calcification. The hypothesis of different pathways for the formation of the primary and secondary calcification is supported by the observed cell elongation associated with thicker and higher Mg/Ca primary calcification, the inverse correlation of primary and secondary calcification thickness, and the absence of primary calcification in the newly formed wall cutting off an epithallial cell from the meristem.
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Giachelli, CM. "Inducers and inhibitors of biomineralization: lessons from pathological calcification". Orthodontics and Craniofacial Research 8, nr 4 (listopad 2005): 229–31. http://dx.doi.org/10.1111/j.1601-6343.2005.00345.x.

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Gutner-Hoch, Eldad, Hiba Waldman Ben-Asher, Ruth Yam, Aldo Shemesh i Oren Levy. "Identifying genes and regulatory pathways associated with the scleractinian coral calcification process". PeerJ 5 (20.07.2017): e3590. http://dx.doi.org/10.7717/peerj.3590.

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Reef building corals precipitate calcium carbonate as an exo-skeleton and provide substratum for prosperous marine life. Biomineralization of the coral’s skeleton is a developmental process that occurs concurrently with other proliferation processes that control the animal extension and growth. The development of the animal body is regulated by large gene regulatory networks, which control the expression of gene sets that progressively generate developmental patterns in the animal body. In this study we have explored the gene expression profile and signaling pathways followed by the calcification process of a basal metazoan, the Red Sea scleractinian (stony) coral,Stylophora pistillata. When treated by seawater with high calcium concentrations (addition of 100 gm/L, added as CaCl2.2H2O), the coral increases its calcification rates and associated genes were up-regulated as a result, which were then identified. Gene expression was compared between corals treated with elevated and normal calcium concentrations. Calcification rate measurements and gene expression analysis by microarray RNA transcriptional profiling at two time-points (midday and night-time) revealed several genes common within mammalian gene regulatory networks. This study indicates that core genes of the Wnt and TGF-β/BMP signaling pathways may also play roles in development, growth, and biomineralization in early-diverging organisms such as corals.
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Nam, Onyou, Iwane Suzuki, Yoshihiro Shiraiwa i EonSeon Jin. "Association of Phosphatidylinositol-Specific Phospholipase C with Calcium-Induced Biomineralization in the Coccolithophore Emiliania huxleyi". Microorganisms 8, nr 9 (10.09.2020): 1389. http://dx.doi.org/10.3390/microorganisms8091389.

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Biomineralization by calcifying microalgae is a precisely controlled intracellular calcification process that produces delicate calcite scales (or coccoliths) in the coccolithophore Emiliania huxleyi (Haptophycea). Despite its importance in biogeochemical cycles and the marine environment globally, the underlying molecular mechanism of intracellular coccolith formation, which requires calcium, bicarbonate, and coccolith-polysaccharides, remains unclear. In E. huxleyi CCMP 371, we demonstrated that reducing the calcium concentration from 10 (ambient seawater) to 0.1 mM strongly restricted coccolith production, which was then recovered by adding 10 mM calcium, irrespective of inorganic phosphate conditions, indicating that coccolith production could be finely controlled by the calcium supply. Using this strain, we investigated the expression of differentially expressed genes (DEGs) to observe the cellular events induced by changes in calcium concentrations. Intriguingly, DEG analysis revealed that the phosphatidylinositol-specific phospholipase C (PI-PLC) gene was upregulated and coccolith production by cells was blocked by the PI-PLC inhibitor U73122 under conditions closely associated with calcium-induced calcification. These findings imply that PI-PLC plays an important role in the biomineralization process of the coccolithophore E. huxleyi.
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Rozprawy doktorskie na temat "Biomineralization/calcification"

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Zhao, Yong. "An AFM study of calcite dissolution in water and selected amino acids". Thesis, Georgia Institute of Technology, 1997. http://hdl.handle.net/1853/25733.

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Gilis, Melany. "Biomineralization of basal skeletons in recent hypercalcified sponges: a submicronic to macroscopic model". Doctoral thesis, Universite Libre de Bruxelles, 2011. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209859.

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Biologically controlled mineralization implies that organisms devote a part of their physiological activity to build up a specific mineralized skeleton. A preliminary comprehensive general view of the morphology and physiology of a given organism is therefore required before trying to understand where and how its biomineralizing system functions. Furthermore, the entire biomineralization sequence is not mediated by purely inorganic mineralogical rules but rather by a cellular machinery. Accordingly, a mineralogical characterization should be linked to a histological and cytological investigation of mineralizing cells to understand how a skeleton is produced. In the present thesis, we developed such a multi-disciplinary approach of some biomineralization processes of the massive basal skeleton in a few Recent hypercalcified sponges, likely survivors from Palaeozoic and early Mesozoic seas.

The three first chapters of this thesis are dedicated to the Mediterranean Calcarea Petrobiona massiliana, a conveniently accessible living hypercalcified sponge whereas all other Recent hypercalcified species are tropical and less easily reached. This model species permitted an initial morphological approach followed by an integrated biological and mineralogical study of biomineralization mechanisms. The fourth chapter aims at the comparative mineralogical study of the basal skeleton of eight tropical Recent hypercalcified demonsponges.

In the first chapter, important modifications and/or morphogenesis at the tissular or cellular level in response to life cycle phases and environmental conditions were depicted in specimens of Petrobiona massiliana. A survey of “storage cells” filling trabecular tracts, which are specific to P. massiliana, suggested that these cells may provide energy and a pool of toti- or pluripotent cells able to restructure the aquiferous system and repopulate cell types like pinacocytes. This potentiality of "storage cells would allow the sponge to sustain important physiological activities, like calcification, along its life cycle. Furthermore, basopinacocytes, cells delineating basally the soft tissue from the underlying basal skeleton, were identified through ultrastructural observations as the most probable cell type involved in the formation of the basal skeleton.

In the second chapter, the skeleton was found to be composed of ca. 50 to 100 nm crystallized grains as the smallest skeletal units, likely initially deposited in a mushy amorphous state. TEM and SEM observations further highlighted that these submicronic grains were assembled in clusters or fibres, the later even laterally associated into bundles. A model of crystallization propagation through amorphous submicronic granular units is proposed to explain the single-crystal feature of these micron-scale structural units, as demonstrated by selected area electron diffraction (SAED) in TEM. Finally, these units were assembled into a defined microstructure forming flattened growth layers called "sclerodermites", which superposed to produce the massive basal skeleton. In addition, X-ray diffraction (XRD) and energy electron loss spectroscopy (EELS) analyses highlighted respectively heterogeneous concentration and spatial distribution of Mg and Ca ions in the skeleton and structural units. This characterization highlighted mineralogical features, not conforming to the inorganic principles, and presuming a highly biologically regulated construction of the basal skeleton.

Accordingly, in the third chapter, it arose that the endomembrane system of basopinacocytes might play a dual function in the production and transport of both mineralizing ions and organic matrices. Combining partial decalcification methods with histochemical dyes and observing ultra-thin sections of the mature basal skeleton in TEM, very spatially and functionally diverse organic matrix components were found to occur in growing and mature portions of the skeleton. The following model of biomineralization was proposed for Petrobiona massiliana: basopinacocytes would use the endomembrane system pathway to produce and carry organic-coated submicronic amorphous grains in a mushy state within intracellular vesicles. These would then be released through the basal cell membrane toward the growing layer of the skeleton, where a highly structured gel-like organic framework, rich in sulfated/acidic GAGs-rich macromolecules, secreted by basopinacocytes, would ensure their assemblage into oriented fibres or clusters.

In the fourth chapter, the basal skeleton of eight tropical Recent hypercalcified species belonging to demosponges: Acanthochaetetes wellsi, Willardia caicosensis, Astrosclera willeyana, Ceratoporella nicholsoni, Goreauiella auriculata, Hispidopetra miniana, Stromatospongia norae and Calcifibrospongia actinostromarioides, were compared. Some mineralogical nano- to submicronic patterns already observed in the Calcarea P. massiliana, appeared as general features: the occurrence of submicronic granular units, their coherent assemblage into monocrystalline fibres and bundles and the likely presence of organic material around all structural units. Additional features brought new insights in our comprehension of biomineralization mechanisms in hypercalcified sponges. Among them, micro-twin and stacking-fault planes aligned with the fibres/bundles axis and crossing over submicronic granular units characterized the skeleton of most aragonitic species. This highly supports the crystallization propagation model proposed for P. massiliana, although it additionally suggests that it should occur only after the oriented assemblage of submicronic grains. Furthermore, lighter transverse striations separated by few nanometres occurred systematically in fibres and bundles of the eight basal skeletons investigated, suggesting the involvement of nanoscale intracrystalline fibrils in the biological control.

In conclusion, this comparative study of nine Recent hypercalcified sponges belonging to phylogenetically distant taxa resulted in the proposition of a shared biomineralization model based on the production of micron and submicron-scale structural units to build up macro-scale basal skeletons under a high biological control. We suggest that the cellular toolkit used for the biologically controlled biomineralization in these sponges is very ancient

and was already developed by their early Palaeozoic ancestors. Furthermore, this model supports recent concepts of calcium carbonate biomineralization developed for example in corals, molluscs and echinoderms, suggesting an even more universal and ancestral character of initial biomineralization mechanisms in all Metazoa producing a calcium carbonate skeleton.

La minéralisation biologiquement contrôlée implique qu’un organisme consacre une partie de son activité physiologique à l'élaboration de son squelette. La connaissance de sa morphologie et de sa physiologie est donc une étape préliminaire indispensable pour comprendre les mécanismes de formation de celui-ci. L’entièreté du processus de biominéralisation ne dépend pas simplement de principes fondamentaux issus de la minéralogie inorganique mais aussi de mécanismes cellulaires particuliers. La caractérisation minéralogique d'un squelette devrait donc être systématiquement liée à une étude histologique et cytologique des cellules impliquées dans la formation du biominéral. La thèse présentée ici a suivi une telle approche multidisciplinaire de certains mécanismes de biominéralisation du squelette basal de plusieurs éponges hypercalcifiées actuelles, considérées comme reliques d'espèces plus anciennes du Paléozoïque et Mésozoïque.

Les trois premiers chapitres de cette thèse concernent l'espèce calcaire de Méditerranée, Petrobiona massiliana, une éponge hypercalcifiée actuelle plus accessible que d'autres principalement distribuées dans les mers tropicales. Une approche de sa morphologie générale a été réalisée en préliminaire à une étude de ses mécanismes de biominéralisation, intégrant une caractérisation minéralogique et biologique. Le quatrième chapitre compare d’un point de vue minéralogique le squelette basal de huit autres espèces hypercalcifiées tropicales appartenant aux démosponges.

Au cours du premier chapitre, d'importantes modifications morphogénétiques à l'échelle tissulaire et cellulaire, liées à certaines phases du cycle biologique et aux conditions environnementales, ont ainsi été mises en évidence chez Petrobiona massiliana. Par l'observation de modifications de l'organisation et de l'ultrastructure des cellules de réserves remplissant les cordons trabéculaires, structures spécifiques de l'espèce, un rôle dans l'approvisionnement nutritif des cellules de l'éponge ainsi qu'un caractère toti- ou pluripotent leur ont été conférés. Les fonctions potentielles de ces cellules dites de réserves pourraient permettre à l'éponge de maintenir des activités physiologiques importantes, telles que la calcification, au cours de son cycle vital. Finalement, l'analyse ultrastructurale des tissus de P. massiliana a permis d'identifier les basopinacocytes, cellules délimitant les tissus mous du squelette basal, comme le type cellulaire ayant le plus de probabilité d'être impliqué dans la formation de ce dernier.

Dans le deuxième chapitre, des granules de 50 à 100 nm de diamètre se sont avérés les plus petites unités structurales du squelette basal de Petrobiona massiliana, probablement déposées initialement dans un état amorphe à consistance molle. Des observations en MEB et MET ont mis en évidence l'assemblage de ces granules en amas ou fibres, ces dernières étant elles-mêmes latéralement associées en faisceaux. Un modèle impliquant la propagation de la

cristallisation au travers de ces assemblages de granules submicroniques a été établi pour expliquer le caractère monocristallin des unités microstructurales, démontré par diffraction électronique en MET. Leur assemblage en une microstructure particulière produisant des couches\
Doctorat en Sciences
info:eu-repo/semantics/nonPublished

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Capasso, Laura. "Molecular insight into ion transport for calcification in symbiotic and non-symbiotic corals". Electronic Thesis or Diss., Sorbonne université, 2021. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2021SORUS258.pdf.

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La construction et le maintien des récifs coralliens dépendent essentiellement de la calcification des coraux, organismes qui produisent un squelette rigide fait de CaCO3, sous la forme cristalline d'aragonite. La plupart de ces coraux vivent en symbiose avec des dinoflagellés photosynthétiques de la famille des Symbiodiniaceae, qui fournissent de l'énergie et des nutriments à l'hôte corallien. Compte tenu de l'importance écologique des coraux constructeurs de récifs, de nombreux progrès ont été réalisés dans l'identification des mécanismes à la base de la calcification des coraux. Néanmoins, il existe encore des lacunes importantes dans la compréhension de ce processus, dont la caractérisation des transporteurs d'ions, utilisés par les cellules calcifiantes pour promouvoir la calcification. Pour contribuer à ce manque de connaissances, des approches ciblées et générales, couplées à des outils moléculaires et bioinformatiques, ont été utilisées tout au long de cette thèse. En utilisant l'approche ciblée, j'ai recherché, dans le génome et le transcriptome du corail symbiotique Stylophora pistillata, des protéines de transport d'ions, précédemment rapportées comme étant impliquées dans la calcification d'autres espèces calcifiantes. En utilisant une approche générale, j'ai étendu la recherche de gènes candidats chez le corail non symbiotique Tubastraea spp. Les deux approches ont contribué à une meilleure compréhension des mécanismes de transport d'ions utilisés par les cellules calcifiantes du corail pour favoriser la calcification dans ce groupe d'animaux marins écologiquement important
The construction and maintenance of coral reefs primarily depends on the calcification of corals, which produce a rigid skeleton made of CaCO3 in the crystalline form of aragonite. Most reef-building corals live in symbiosis with photosynthetic dinoflagellates of the Symbiodiniaceae family, which provide the coral host with energy and nutrients. Given their ecological importance, much progress has been made in identifying key elements of the mechanisms underlying coral calcification. Nevertheless, there are still significant gaps in our understanding. Foremost is the characterization of ion transporters, used by the coral calcifying cells to promote calcification. To contribute to this lack of knowledge, targeted and broad approaches, coupled with molecular and bioinformatics tools, have been used throughout this thesis. Using the targeted approach, ion transporter proteins, previously reported to be involved in calcification of other calcifying species, have been identified for the first time in the genome and transcriptome of the symbiotic coral Stylophora pistillata. Whereas, using a broad approach, novel candidate genes for roles in calcification have been identified in the non-symbiotic coral Tubastraea spp. Overall, both approaches contributed to a better understanding of the ion transporting mechanisms used by the coral calcifying cells to promote calcification in this ecologically important group of marine animals
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Szabó, Réka. "Regeneration and calcification in the Spirobranchus lamarcki operculum : development and comparative genetics of a novel appendage". Thesis, University of St Andrews, 2015. http://hdl.handle.net/10023/7697.

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Regeneration, the replacement of lost or damaged body parts, and biomineralisation, the biologically controlled formation of minerals, are important and widespread abilities in the animal kingdom. Both phenomena have a complex evolutionary history; thus their study benefits from investigations in diverse animals. Spirobranchus (formerly Pomatoceros) lamarcki is a small tube-dwelling polychaete worm of the serpulid family. Serpulids have evolved a novel head appendage, the operculum, which functions as a defensive tube plug and regenerates readily when lost. In S. lamarcki, the end of the operculum is reinforced by a calcareous plate; thus, the operculum is a good system in which to study both regeneration and biomineralisation. This thesis explores several aspects of these important processes in the adult operculum. First, a time course of normal regeneration is established. Next, cell proliferation patterns are described, suggesting a combination of proliferation-dependent and proliferation-independent elements in opercular regeneration. The formation of the calcareous opercular plate is examined using both microscopic observations of whole opercular plates and X-ray diffraction analysis of isolated plate mineral, revealing a large shift in mineralogy over the course of regeneration. Histochemical study of alkaline phosphatase enzyme activity indicates the importance of these enzymes in the operculum, although their precise functions are as yet unclear. Finally, a preliminary survey of three opercular transcriptomic datasets is presented, with a broad sampling of gene families with regeneration- or biomineralisation-related roles in other animals. The opercular transcriptome constitutes the first biomineralisation transcriptome from any annelid, and one of the first transcriptomic datasets related to annelid regeneration. Many of the candidate genes examined here display interesting behaviour and suggest targets for further investigation. The work presented here establishes the S. lamarcki operculum as a promising model system in the field of evolutionary developmental biology.
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Clark, Ruti H. "A model system for investigating biomineralization : elucidating protein G/calcium oxalate monohydrate interactions /". Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/8067.

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Somogyi-Ganss, Eszter. "Novel non-collagenous modulators of biomineralization in bone and dentin /". Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-101-6/.

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Stapane, Lilian. "Biominéralisation de la coquille d oeuf de poule : mise en évidence d'un transport vésiculaire du minéral impliquant les protéines EGF-like repeats and discoidin-like domains 3 (EDIL3) et Milk fat globule EGF-factor 8 (MFGE8)". Thesis, Tours, 2019. http://www.theses.fr/2019TOUR4026.

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L’œuf de poule est une chambre aseptique et autosuffisante qui permet le développement harmonieux du poussin en 21 jours. La coquille constitue la première barrière physique de l’œuf et protège ce dernier contre les agressions physiques et microbiennes. Lors de la minéralisation de la coquille dans le fluide utérin, la matrice organique secrétée par l’utérus de la poule joue un rôle prépondérant. Pour décrypter le rôle de deux protéines majeures de la matrice organique (EGF-like repeats and discoidin-like domains 3 : EDIL3 et Milk fat globule EGF-factor 8 : MFGE8), différentes approches in silico et expérimentales ont été réalisées. Ainsi, nous avons retracé l’histoire évolutive de ces deux protéines, qui indique une divergence d’EDIL3 et MFGE8, il y a environ 480 millions d’années. Les résultats obtenus nous ont également permis de mettre en évidence un transport vésiculaire du minéral (carbonate de calcium amorphe), impliqué dans ce phénomène de biominéralisation. EDIL3 et MFGE8 joueraient un rôle prépondérant dans ce mécanisme en participant à l’adressage sur le site de minéralisation. Ce travail a été complété par une analyse des autres acteurs moléculaires du transport vésiculaire. Ces acteurs participent au fonctionnement vésiculaire, à l’apport du calcium et des bicarbonates vésiculaires, ainsi qu’à la stabilisation du carbonate de calcium amorphe. Pour finir, nous proposons un modèle global et cohérent du transport des précurseurs minéraux nécessaires à la minéralisation de la coquille. Ce modèle impliquerait trois voies (transcellulaire, vésiculaire et paracellulaire) dont les rôles respectifs devront être explorés
The chicken egg is an aseptic and a self-sufficient chamber allowing the harmonious development of the chicken embryo in 21 days. The eggshell is the first physical barrier of the egg, which protects the egg from mechanical and microbial stresses. During eggshell biomineralization in the uterine fluid, the organic matrix, which is secreted by the uterus, ensures a crucial role in this process. To decipher the role of two major proteins of the organic matrix (EGF-like repeats and discoidin-like domains 3 : EDIL3 et Milk fat globule EGF-factor 8 : MFGE8), in silico and experimental approaches were performed. We firstly investigated the common evolution history of EDIL3 and MFGE8. We have estimated a divergent point between both paralogs 480 million years ago. The results also allowed us to highlight a vesicular transport of mineral (amorphous calcium carbonate) involved in eggshell biomineralization. EDIL3 and MFGE8 proteins would guide the vesicles to the mineralizing site and consequently ensure a critical role in this transport. This work also described additional molecular actors involved in vesicles formation, in calcium and bicarbonates supply and to the stabilization of amorphous calcium carbonate. We therefore proposed a global and coherent model of mineral transport during eggshell calcification. In this model, three alternative pathways could be involved (transcellular, vesicular and paracellular). Further investigations will be necessary to determine the respective roles of these pathways
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Shiraishi, Fumito. "Microbial metabolisms and calcification in freshwater biofilms". Doctoral thesis, 2008. http://hdl.handle.net/11858/00-1735-0000-000D-F148-1.

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Ajikumar, Parayil Kumaran, Rajamani Lakshminarayanan, Suresh Valiyaveettil i R. Manjunatha Kini. "Eggshell Matrix Protein Mimetics: Elucidation of Molecular Mechanism of Goose Eggshell Calcification using Designed Peptides". 2003. http://hdl.handle.net/1721.1/3929.

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Model peptides were designed, synthesized and conducted a detailed structure-property study to unravel the molecular mechanism of goose eggshell calcification. The peptides were designed based on the primary structural features of the eggshell matrix proteins ansocalcin and OC-17. In vitro CaCO₃ crystal growth experiments in presence of these peptides showed calcite crystal aggregation as observed in the case of the parent protein ansocalcin. The structure of these peptides in solution was established using intrinsic tryptophan fluorescence studies and quasi-elastic light scattering experiments. The structural features are correlated with observed results of the in vitro crystallization studies.
Singapore-MIT Alliance (SMA)
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Abraham, José Amado. "Estudio de los mecanismos de cristalización y maduración de fosfatos de calcio en medio biológico usando radiación de sincrotrón /". Doctoral thesis, 2009. http://hdl.handle.net/11086/150.

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Tesis (Doctor en Física)--Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física, 2009.
Este trabajo ha tenido como propósito ofrecer resultados concluyentes y proponer nuevos puntos de referencia en el tema de la cristalización de fosfatos de calcio en un entorno biológico, específicamente, la formación de cálculo dental. Si bien ésta afección no es una enfermedad, de igual manera ha tomado la atención de científicos de diversas áreas, como la medicina, la biología y la química. A la pregunta de '¿por qué sería importante estudiar el fenómeno de cristalización en fosfatos biológicos?' habría tres respuestas. La primera, ayudaría a entender el fenómeno de formación de depósitos pétreos en la boca que si bien no implica gran molestia o dolor, es comprobado que es disparador de severas enfermedades bucales crónicas como la periodontitis, además, claves en el estudio de formación también podría ser aplicable a otros depósitos pétreos como cálculos renales que en la mayoría de los casos requiere intervención quirúrgica. La segunda, podría revelar aspectos fundamentales en la formación de tejido óseo que serían de utilidad en la terapia de rehabilitación o en la recalcificación de fracturas óseas y más aun la enfermedad frecuente de personas mayores, la osteoporosis. La tercera, entender la fisicoquímica del proceso ofrecería un gran aporte para la fabricación de mejores prótesis óseas y dentales con un muy bajo nivel de rechazo por el organismo.
José Amado Abraham.
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Książki na temat "Biomineralization/calcification"

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International Conference on the Chemistry and Biology of Mineralized Tissues (2nd 1984 Gulf Shores, Ala.). The chemistry and biology of mineralized tissues: Proceedings of the Second International Conference on the Chemistry and Biology of Mineralized Tissues, held in Gulf Shores, Alabama, September 9-14, 1984. [S.l: s.n.], 1985.

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International Conference on the Chemistry and Biology of Mineralized Tissues (2nd 1984 Gulf Shores, Ala.). The chemistry and biology of mineralized tissue: Proceedings of the second International Conference on the Chemistry and Biology of Mineralized Tissues, held in Gulf Shores, Alabama, September 9-14, 1984. Birmingham, Ala: Ebsco Media, 1985.

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François, Doumenge, Allemand Denis, Toulemont Anne, International Union for Conservation of Nature and Natural Resources. Commission on Ecology. i International Biomineralization Symposium (7th : 1993 : Monaco, Monaco), red. Past and present biomineralization processes: Considerations about the carbonate cycle : IUCN--COE workshop, Monaco, 15-16 November 1993. Monaco: Musée océanographique, 1994.

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Erich, Königsberger, i Königsberger LanChi, red. Biomineralization: Medical aspects of solubility. Chichester, West Sussex, England: John Wiley & Sons, 2006.

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International Conference on the Chemistry and Biology of Mineralized Tissues (3rd 1988 Chatham, Mass.). The chemistry and biology of mineralized tissues: Proceedings of the Third International Conference on the Chemistry and Biology of Mineralized Tissues, held in Chatham, Massachusetts on October 16-21, 1988. New York: Gordon and Breach, 1989.

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M, Driessens F. C., i Verbeeck R. M. H, red. Biominerals. Boca Raton: CRC Press, 1990.

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1927-, Suga S., Nakahara Hiroshi, Nihon Gakujutsu Kaigi, Kanagawa Academy of Science and Technology. i International Symposium on Biomineralization (6th : 1990 : Odaware-shi, Japan), red. Mechanisms and phylogeny of mineralization in biological systems. Tokyo: Springer-Verlag, 1991.

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The subchondral bone plate. Berlin: Springer, 1998.

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C, Slavkin Harold, i Price Paul A, red. Chemistry and biology of mineralized tissues: Proceedings of the Fourth International Conference on the Chemistry and Biology of Mineralized Tissues held in Coronado, California on February 5-9, 1992. Amsterdam: Excerpta Medica, 1992.

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International, Workshop on Calcified Tissues (6th 1984 Kiryat ʻAnavim Israel). Current advances in skeletogenesis: Induction, biomineralization, bone seeking hormones, congenital and metabolic bone diseases : proceedings of the Sixth International Workshop on Calcified Tissues, Kiryat-Anavim, Israel, 18-23 March 1984. Amsterdam: Excerpta Medica, 1985.

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Części książek na temat "Biomineralization/calcification"

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Jahnen-Dechent, Willi. "Lot's Wife's Problem Revisited: How We Prevent Pathological Calcification". W Biomineralization, 243–67. Weinheim, FRG: Wiley-VCH Verlag GmbH & Co. KGaA, 2005. http://dx.doi.org/10.1002/3527604138.ch15.

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Mishima, Hiroyuki, Saki Tanabe, Atsuhiko Hattori, Nobuo Suzuki, Mitsuo Kakei, Takashi Matsumoto, Mika Ikegame, Yasuo Miake, Natsuko Ishikawa i Yoshiki Matsumoto. "The Relationship Between the Structure and Calcification of Dentin and the Role of Melatonin". W Biomineralization, 199–209. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-1002-7_21.

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Boyan, Barbara D., Larry D. Swain i Ruben Gomez. "Model for Prokaryotic Calcification". W Origin, Evolution, and Modern Aspects of Biomineralization in Plants and Animals, 517–23. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4757-6114-6_40.

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Schoknecht, Jean D., i Harold W. Keller. "Peridial Calcification in the Myxomycetes". W Origin, Evolution, and Modern Aspects of Biomineralization in Plants and Animals, 455–88. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4757-6114-6_36.

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Clark, George R. "Invertebrate Growth Lines: Measures of Tempo and Mode in Calcification". W Skeletal Biomineralization: Patterns, Processes and Evolutionary Trends, 328. Washington, D. C.: American Geophysical Union, 2013. http://dx.doi.org/10.1029/sc005p0328.

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Constantz, Brent, i Annemarie Meike. "Calcite Centers of Calcification in Mussa Angulosa (Scleractinia)". W Origin, Evolution, and Modern Aspects of Biomineralization in Plants and Animals, 201–7. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4757-6114-6_14.

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Setoguchi, Hiroaki, Megumi Okazaki i Shoichi Suga. "Calcification in Higher Plants with Special Reference to Cystoliths". W Origin, Evolution, and Modern Aspects of Biomineralization in Plants and Animals, 409–18. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4757-6114-6_32.

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Pentecost, Allan. "Growth and Calcification of Calothrix — Dominated Oncolites from Northern England". W Origin, Evolution, and Modern Aspects of Biomineralization in Plants and Animals, 443–54. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4757-6114-6_35.

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Mitterer, Richard M. "Composition and Association of Organic Matter with Calcium Carbonate and the Origin of Calcification". W Origin, Evolution, and Modern Aspects of Biomineralization in Plants and Animals, 309–23. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4757-6114-6_24.

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Kemp, Norman E. "The Phosphatic Mode of Calcification in Ontogeny and Phylogeny of the Integument and Skeleton of Vertebrates". W Origin, Evolution, and Modern Aspects of Biomineralization in Plants and Animals, 237–49. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4757-6114-6_17.

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