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Artykuły w czasopismach na temat "Biological and Medical Chemistry"
Stechenko, Olena. "BIOLOGICAL AND BIOORGANIC CHEMISTRY IN THE MEDICAL CURRICULA". Science and Education 2019, nr 2 (luty 2019): 5–12. http://dx.doi.org/10.24195/2414-4665-2019-2-1.
Pełny tekst źródłaKornberg, Arthur. "Chemistry — the lingua franca of the medical and biological sciences". Chemistry & Biology 3, nr 1 (styczeń 1996): 3–5. http://dx.doi.org/10.1016/s1074-5521(96)90075-7.
Pełny tekst źródłaLesyk, Roman. "Drug design: 4-thiazolidinones applications. Part 1. Synthetic routes to the drug-like molecules". Journal of Medical Science 89, nr 1 (31.03.2020): e406. http://dx.doi.org/10.20883/medical.406.
Pełny tekst źródłaHogg, Neil. "Biological chemistry and clinical potential of S-nitrosothiols". Free Radical Biology and Medicine 28, nr 10 (maj 2000): 1478–86. http://dx.doi.org/10.1016/s0891-5849(00)00248-3.
Pełny tekst źródłaKoppenol, W. H. "Superoxide ion: Chemistry and biological implications, volume I". Free Radical Biology and Medicine 9, nr 6 (styczeń 1990): 541. http://dx.doi.org/10.1016/0891-5849(90)90132-3.
Pełny tekst źródłaKoppenol, W. H. "Superoxide ion: Chemistry and biological implications, volume II". Free Radical Biology and Medicine 12, nr 5 (styczeń 1992): 449. http://dx.doi.org/10.1016/0891-5849(92)90094-w.
Pełny tekst źródłaKawase, Masami, Setsuo Saito i Noboru Motohashi. "Chemistry and biological activity of new 3-benzazepines". International Journal of Antimicrobial Agents 14, nr 3 (kwiecień 2000): 193–201. http://dx.doi.org/10.1016/s0924-8579(99)00155-7.
Pełny tekst źródłaLiang, Pi-Hui, Chung-Yi Wu, William A. Greenberg i Chi-Huey Wong. "Glycan arrays: biological and medical applications". Current Opinion in Chemical Biology 12, nr 1 (luty 2008): 86–92. http://dx.doi.org/10.1016/j.cbpa.2008.01.031.
Pełny tekst źródłaAli, Fayaz, Narayan S Hosmane i Yinghuai Zhu. "Boron Chemistry for Medical Applications". Molecules 25, nr 4 (13.02.2020): 828. http://dx.doi.org/10.3390/molecules25040828.
Pełny tekst źródłaAmirov, N. K., i Т. A. Abdullin. "70th anniversary of the Department of Inorganic Chemistry of Kazan State Medical University". Kazan medical journal 80, nr 2 (25.03.1999): 158–59. http://dx.doi.org/10.17816/kazmj66496.
Pełny tekst źródłaRozprawy doktorskie na temat "Biological and Medical Chemistry"
Nichols, Alexander J. "Optical Molecular Sensing in Complex Biological Environments". Thesis, Harvard University, 2014. http://nrs.harvard.edu/urn-3:HUL.InstRepos:14226087.
Pełny tekst źródłaPokhrel, Laxman. "Design, synthesis, and biological evaluation of tricyclic pyrones and thiouridine nucleosides". Diss., Kansas State University, 2013. http://hdl.handle.net/2097/16233.
Pełny tekst źródłaDepartment of Chemistry
Duy H. Hua
The first chapter in this thesis includes the design, synthesis, and evaluation of anti-Alzheimer and anti-norovirus activities of tricyclic pyrones (TPs). Alzheimer’s disease is a major cause of dementia and sixth leading cause of death; it is a growing problem all over the world. On the other hand, norovirus, a highly contagious agent is responsible for more than 90% of non-bacterial gastroenteritis causing severity mainly in the closed environments. No drugs exist to eradicate the symptoms developed by both of these disorders. Studies have shown that the development of Alzheimer’s disease and the infection of norovirus are dependent on cholesterol metabolism. More specifically, the inhibition of acyl-CoA: cholesterol acyltrasferase (ACAT) led to the reduction of plaques in Alzheimer’s disease as well as reduced the infection of norovirus. Mimicking the structure of CP2, a TP with promising anti-Alzheimer activities, a library of tricyclic pyrones containing phenyl, naphthyl, heterocyclic, and dipeptidyl moieties were synthesized and evaluated for their anti-Alzheimer and anti-norovirus efficacies. Several TPs containing phenyl and naphthyl groups showed sub-micromolar to nanomolar potencies for the protection of neuronal MC65 cells from Aβ-oligomers induced death. Similarly, the TPs containing pyrrolyl, imidazolyl, and quinolinyl moieties were effective to inhibit the norovirus replication in low micromolar range. The most effective TPs from MC65 cells protection assay were also effective in the inhibition ACAT and up-regulation ABCA1 gene. The second chapter in this thesis includes the design, synthesis, and anti-norovirus activity of thiouridine nucleosides. Many nucleosides have demonstrated effective inhibition of viral RNA polymerase, and some are progressing at different level of clinical trials for the treatment of hepatitis C virus. Some of the nucleosides, including 2’-C-methyl and 2’-amino substituted analogs, were found to effectively inhibit the norovirus replication. In the search of more potent anti-noroviral compounds, two thiouridine nucleosides were synthesized and evaluated as anti-norovirus agents. Both of these analogs were ineffective up to 50 μM for the inhibition of norovirus replication in cell based assay. Proposed work of converting these nucleosides to their phosphoramidate derivatives is also described.
Njaria, Paul Magutu. "Antimycobacterial 2-aminoquinazolinones and benzoxazole-based oximes: synthesis, biological evaluation, physicochemical profiling and supramolecular derivatization". Doctoral thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/26954.
Pełny tekst źródłaForsyth, Andrea N. "Synthesis and Biological Evaluation of Rigid Analogues of Methamphetamines". ScholarWorks@UNO, 2012. http://scholarworks.uno.edu/td/1436.
Pełny tekst źródłaZhu, Chongyu. "Polymeric drug delivery systems for biological antimicrobial agents". Thesis, University of Warwick, 2017. http://wrap.warwick.ac.uk/91996/.
Pełny tekst źródłaShi, Fengjian. "LASER ELECTROSPRAY MASS SPECTROMETRY: INSTRUMENTATION AND APPLICATION FOR DIRECT ANALYSIS AND MOLECULAR IMAGING OF BIOLOGICAL TISSUE". Diss., Temple University Libraries, 2017. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/445496.
Pełny tekst źródłaPh.D.
This dissertation elucidates the instrumentation and application of a hybrid ambient ionization source, laser electrospray mass spectrometry (LEMS), for the direct analysis and molecular imaging of biological tissue without matrix deposition. In LEMS, laser pulses from a Ti:Sapphire laser amplifier (60 fs, 800 nm, and 1 mJ) interact with surface analytes and transfer them from the condensed phase into the gas phase without the requirement of either exogenous matrix or endogenous water in the sample. The laser vaporized analytes are captured and ionized by an electrospray source, and finally detected by a mass analyzer. It was found that a turn-key, robust femtosecond fiber laser with longer wavelength, longer duration, and lower pulse energy at 1042 nm, 425 fs, and 50 µJ, respectively, provided comparable results with the Ti:Sapphire laser. Vaporization of intact, dried or aqueous cytochrome c and lysozyme samples was demonstrated by the fiber laser. A charge states distribution at lower charge states indicating folded conformation of proteins and the hemoglobin α subunit-heme complex from whole blood was observed. Endogenous anthocyanins, sugars, and other metabolites were detected and revealed the anticipated metabolite profile for the flower petal and leaf samples by the fiber laser. Phospholipids, especially phosphatidylcholine, were identified from a fresh mouse brain section sample. These lipid features were suppressed in both the fiber laser and Ti:Sapphire LEMS measurement in the presence of optimal cutting temperature compounds which are commonly used in animal tissue cryosectioning. This dissertation also details the design of an automated mass spectrometry imaging source based on the Ti:Sapphire LEMS. The laser, translation stage, and mass analyzer are synchronized and controlled using a customized user interface to enable step-by-step scanning of the area of interest on a given tissue sample. The imaging source is coupled with a high resolution accurate mass quadrupole time-of-flight (QTOF) mass analyzer with tandem mass analysis capability. A lateral resolution of 60 µm was demonstrated on a patterned ink film by LEMS imaging. Plant metabolites including sugar and anthocyanins were directly imaged from a leaf sample. Small metabolites, lipids and proteins were simultaneously imaged from a single tissue section of a pig liver sample. Biomarkers of blood-brain barrier damage and traumatic brain injury (TBI) that occurred during the injury were detected and imaged from a TBI mouse brain. The loading values from principal component analysis (PCA) were shown to be useful for identification of features of interest from the large LEMS imaging dataset.
Temple University--Theses
Jaramillo, Forcada Tatiana. "Synthesis and biological evaluation of natural and synthetic ganoderic acids". Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/43313/.
Pełny tekst źródłaPetersson, Nina. "Optimisation of capillary gel electrophoresis method for enhanced separation of mRNA shortmers". Thesis, Uppsala universitet, Institutionen för kemi - BMC, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-351119.
Pełny tekst źródłaVerma, Abha. "Design, Synthesis and Biological Evaluation of Novel Cannabinoid Antagonist". ScholarWorks@UNO, 2012. http://scholarworks.uno.edu/td/1527.
Pełny tekst źródłaMuth, Aaron. "Design, Synthesis, and Biological Evaluation of Novel Polyamine Transport System Probes and their Application to Human Cancers". Doctoral diss., University of Central Florida, 2012. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/5348.
Pełny tekst źródłaPh.D.
Doctorate
Chemistry
Sciences
Chemistry
Książki na temat "Biological and Medical Chemistry"
Raymond, Kenneth William. General, organic, and biological chemistry: An integrated approach. Wyd. 2. Hoboken, NJ: Wiley, 2008.
Znajdź pełny tekst źródłaRaymond, Kenneth William. General, organic, and biological chemistry: An integrated approach. Wyd. 3. Hoboken, N.J: Wiley, 2010.
Znajdź pełny tekst źródłaGeneral, organic, and biological chemistry: An integrated approach. Hoboken, NJ: J. Wiley, 2006.
Znajdź pełny tekst źródłaHostettmann, K. Handbook of chemical and biological plant analytical methods. Chichester, West Sussex: John Wiley & Sons Inc., 2014.
Znajdź pełny tekst źródłaS, Subramanian K., i Woittiez J. R. W, red. Element analysis of biological samples: Principles and practice. Boca Raton: CRC Press, 1998.
Znajdź pełny tekst źródłaD, Loike J., red. Lignans: Chemical, biological, and clinical properties. Cambridge [England]: Cambridge University Press, 1990.
Znajdź pełny tekst źródłaGarshin, Anatoliy. General and inorganic chemistry in diagrams, figures, tables, and chemical reactions. ru: INFRA-M Academic Publishing LLC., 2020. http://dx.doi.org/10.12737/1070937.
Pełny tekst źródłaZhou, Michael. Regulated bioanalytical laboratories: Technical and regulatory aspects from global perspectives. Hoboken, N.J: Wiley, 2011.
Znajdź pełny tekst źródłaCéspedes, Carlos L. Natural antioxidants and biocides from wild medicinal plants. Cambridge, MA: CAB International, 2013.
Znajdź pełny tekst źródła1944-, Hostettmann K., Gupta Mahabir P, Marston A. 1953-, International Organization for Chemical Sciences in Development. i CYTED (Organization), red. Chemistry, biological, and pharmacological properties of medicinal plants from the Americas: Proceedings of the IOCD/CYTED Symposium, Panama City, Panama, 23-26 February 1997. Amsterdam, The Netherlands: Harwood Academic Publishers, 1999.
Znajdź pełny tekst źródłaCzęści książek na temat "Biological and Medical Chemistry"
Gorbik, P. P., L. P. Storozhuk, A. A. Chuiko†, L. Yu. Vergun i V. F. Chekhun. "Magnetically sensitive nanocomposites for medical and biological applications". W Surface Chemistry in Biomedical and Environmental Science, 299–306. Dordrecht: Springer Netherlands, 2006. http://dx.doi.org/10.1007/1-4020-4741-x_26.
Pełny tekst źródłaBoitrel, Bernard. "Bismuth Complexes of Porphyrins and their Potential in Medical Applications". W Biological Chemistry of Arsenic, Antimony and Bismuth, 209–40. Chichester, UK: John Wiley & Sons, Ltd, 2010. http://dx.doi.org/10.1002/9780470975503.ch9.
Pełny tekst źródłaVitali, Francesca, i Rudi Fasan. "Biological and Hybrid Biological/Chemical Strategies in Diversity Generation of Peptidic Macrocycles". W Practical Medicinal Chemistry with Macrocycles, 155–84. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2017. http://dx.doi.org/10.1002/9781119092599.ch7.
Pełny tekst źródłaRoda, A., S. Girotti, G. Carrea, P. Simoni, M. A. Angellotti i R. Rizzoli. "Immobilized Biospecific Proteins in Analytical Clinical Chemistry". W Analytical Uses of Immobilized Biological Compounds for Detection, Medical and Industrial Uses, 249–65. Dordrecht: Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-2895-4_21.
Pełny tekst źródłaBrothers, Penelope J., i Christy E. Ruggiero. "Coordination and Solution Chemistry of the Metals: Biological, Medical and Environmental Relevance". W The Group 13 Metals Aluminium, Gallium, Indium and Thallium: Chemical Patterns and Peculiarities, 519–611. Chichester, UK: John Wiley & Sons, Ltd, 2011. http://dx.doi.org/10.1002/9780470976548.ch9.
Pełny tekst źródłaMishra, Bibhudatta, i Gunjan Joshi. "Serotonin: Chemical, Biological, and Therapeutic Aspects". W Handbook of Research on Medicinal Chemistry, 201–37. Toronto ; New Jersey : Apple Academic Press, 2017.: Apple Academic Press, 2017. http://dx.doi.org/10.1201/9781315207414-6.
Pełny tekst źródłaTrisciuoglio, Daniela, i Dante Rotili. "Histone Acetyltransferase Enzymes: From Biological Implications to Most Relevant Inhibitors". W Topics in Medicinal Chemistry, 93–122. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/7355_2019_71.
Pełny tekst źródłaWang, Jianing, Ravindra K. Rawal i Chung K. Chu. "Recent Advances in Carbocyclic Nucleosides: Synthesis and Biological Activity". W Medicinal Chemistry of Nucleic Acids, 1–100. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2011. http://dx.doi.org/10.1002/9781118092804.ch1.
Pełny tekst źródłaHe, Shuqing, i Zhen Cheng. "Advancements of Second Near-Infrared Biological Window Fluorophores: Mechanism, Synthesis, and Application In Vivo". W Topics in Medicinal Chemistry, 81–123. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/7355_2019_89.
Pełny tekst źródłaCarta, Fabrizio, Andrea Angeli, Christian D. T. Nielsen, Claudiu T. Supuran i Agostino Cilibrizzi. "New Biological Targets for the Treatment of Leishmaniasis". W Medicinal Chemistry of Neglected and Tropical Diseases, 281–309. Boca Raton, FL : CRC Press, Taylor & Francis Group, [2018]: CRC Press, 2019. http://dx.doi.org/10.1201/9781351011655-13.
Pełny tekst źródłaStreszczenia konferencji na temat "Biological and Medical Chemistry"
Kaksis, Aris, Agnese Brangule i Mihails Halitovs. "AN APPROACH TO TEACHING MEDICAL CHEMISTRY THAT HIGHLIGHTS INTERDISCIPLINARY NATURE OF SCIENCE". W 1st International Baltic Symposium on Science and Technology Education. Scientia Socialis Ltd., 2015. http://dx.doi.org/10.33225/balticste/2015.54.
Pełny tekst źródłaGonzález-Burgos, Elena, Noelia Fraga Matías, Isabel Maria Ureña Vacas i M. Pilar Gómez-Serranillos. "Biological evaluation of Cetrarioid clade as cholinesterase inhibitors". W 5th International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2019. http://dx.doi.org/10.3390/ecmc2019-06316.
Pełny tekst źródłaRatemi, Elaref, i Denis Gravel. "Design, Synthesis and Biological Activity of Selective PHEX Inhibitors". W 1st International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2015. http://dx.doi.org/10.3390/ecmc-1-a044.
Pełny tekst źródłaKim, Jong H., Kathleen Chan i Luisa Cheng. "Augmenting the efficacy of antifungal intervention via chemo-biological approaches". W 1st International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2015. http://dx.doi.org/10.3390/ecmc-1-a011.
Pełny tekst źródłaSalvador Gil, Daniel, i Mª Concepción Gimeno. "New Thiourea-thiazolidine Complexes and Study of their Biological Activity". W 3rd International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2017. http://dx.doi.org/10.3390/ecmc-3-04665.
Pełny tekst źródłaAuria-Luna, Fernando, M. Eugenia Marqués-López, M. Concepción Gimeno i Raquel P. Herrera. "Organocatalytic Synthesis of Chiral 1,4-Dihydropyridines with Potential Biological Properties". W 3rd International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2017. http://dx.doi.org/10.3390/ecmc-3-04671.
Pełny tekst źródłaFantacuzzi, Marialuigia. "Synthesis, biological evaluation, and docking study of indole aryl sulfonamides as aromatase inhibitors". W 5th International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2019. http://dx.doi.org/10.3390/ecmc2019-06361.
Pełny tekst źródłaSilva-Júnior, Edeildo, Gabriel Passos, Matheus Gomes, Thiago Aquino, Stephannie Souza, João Cavalcante, Elane Santos, Ênio Bassi i João Araújo-Júnior. "Design, synthesis and in vitro biological evaluation of acrylamide derivatives against Chikungunya virus". W 5th International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2019. http://dx.doi.org/10.3390/ecmc2019-06379.
Pełny tekst źródłaMaccallini, Cristina. "Synthesis and biological evaluation of inducible nitric oxide synthase inhibitors as anticancer agents". W 6th International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2020. http://dx.doi.org/10.3390/ecmc2020-07370.
Pełny tekst źródłaBaitiche, Milad, Marc Le Borgne, Dounia Sid, Zineb Elbahri, Ferhat Djerboua i Mokhtar Boutahala. "Development of water-soluble ternary system for enhancing biological activities of mefenamic acid". W 6th International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2020. http://dx.doi.org/10.3390/ecmc2020-07461.
Pełny tekst źródłaRaporty organizacyjne na temat "Biological and Medical Chemistry"
Price, Barbara B. Chemical Biological Medical Treatment Symposia-III. Fort Belvoir, VA: Defense Technical Information Center, kwiecień 2001. http://dx.doi.org/10.21236/ada394695.
Pełny tekst źródłaSidell, Frederick R., Ernest T. Takafuji i David R. Franz. Medical Aspects of Chemical and Biological Warfare. Fort Belvoir, VA: Defense Technical Information Center, styczeń 1997. http://dx.doi.org/10.21236/ada398241.
Pełny tekst źródłaBarr, S. H., red. Division of Biological and Medical Research research summary 1984-1985. Office of Scientific and Technical Information (OSTI), sierpień 1985. http://dx.doi.org/10.2172/6039516.
Pełny tekst źródłaBaker, J., D. Bernard, S. Christensen, M. Sale, J. Freda, K. Heltcher, L. Rowe i in. Biological effects of changes in surface water acid-base chemistry. Office of Scientific and Technical Information (OSTI), styczeń 1990. http://dx.doi.org/10.2172/7255574.
Pełny tekst źródłaBeebe, Steven J. Second International Symposium on Nonthermal Medical/Biological Treatments using Electromagnetic Fields and Ionized Gases. Fort Belvoir, VA: Defense Technical Information Center, maj 2001. http://dx.doi.org/10.21236/ada388316.
Pełny tekst źródłaSchoenbach, Karl H. First International Symposium on Nonthermal Medical/Biological Treatments using Electromagnetic Fields and Ionized Gases. Fort Belvoir, VA: Defense Technical Information Center, listopad 1999. http://dx.doi.org/10.21236/ada376636.
Pełny tekst źródłaCurling, Carl A., i Julia K. Burr. NATO Allied Joint Medical Publication 7: Allied Joint Medical Doctrine for Support to Chemical, Biological, Radiological, and Nuclear (CBRN) Defensive Operations, Final Draft. Fort Belvoir, VA: Defense Technical Information Center, lipiec 2014. http://dx.doi.org/10.21236/ada614619.
Pełny tekst źródłaSutton, M., B. Andresen, S. Burastero, M. Chiarappa-Zucca, S. Chinn, P. Coronado, A. Gash, J. Perkins, A. Sawvel i S. Szechenyi. Modern Chemistry Techniques Applied to Metal Behavior and Chelation in Medical and Environmental Systems ? Final Report. Office of Scientific and Technical Information (OSTI), luty 2005. http://dx.doi.org/10.2172/15015925.
Pełny tekst źródłaChung, Myung, Li Dong, Rong Fu, Lance Liotta, Aarthi Narayanan, Emanuel Petricoin, Mark Ross i in. Rapid Detection of Biological and Chemical Threat Agents Using Physical Chemistry, Active Detection, and Computational Analysis. Office of Scientific and Technical Information (OSTI), styczeń 2007. http://dx.doi.org/10.2172/1049503.
Pełny tekst źródłaBurr, Julia K., Carl A. Curling i Lucas A. LaViolet. Exercise "Dread Night": Using Allied Medical Publication-8(C) to Estimate Chemical, Biological, Radiological, and Nuclear (CBRN) Casualties. Fort Belvoir, VA: Defense Technical Information Center, sierpień 2010. http://dx.doi.org/10.21236/ada531193.
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