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Brown, Coral, i res cand@acu edu au. "The Role of Attachment in a Time-limited Marital Therapy: Implications for practice and treatment". Australian Catholic University. Faculty of Arts and Sciences, 2002. http://dlibrary.acu.edu.au/digitaltheses/public/adt-acuvp14.25072005.
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The present study investigates the role of attachment in a time-limited marital therapy. The study explores Brief Contextual Modular Psychotherapy (BCMT). This approach to practice provides a model that integrates principles and techniques from the major psychotherapies. BCMT can be distinguished from other brief therapies by its theoretical integration, its six-session time limit, its specific clinical focus, and its techniques for dealing with dissatisfaction and distress. The therapy sets out practice modules—six-session treatment plans—for a diverse range of presenting issues such as the anxiety disorders, depression, trauma, loss and grief, marriage and the phobias. BCMT emphasises the collaboration of the therapist and the client. A community-based psychological counselling centre has practised BCMT for over ten years, applying it in cases of wide diversity and maladjustment. Prior to this research, a comprehensive analysis of the theory underlying the BCMT model or the theory of change it endorses had not been carried out. The study provides a detailed description of the conceptual and treatment elements of the marital module developed in the treatment manual for BCMT. The study explores how the construct of attachment provides an organising framework or metaperspective for theory construction and therapeutic intervention in the clinical application of this time-limited marital therapy. To achieve this objective, one de-facto and four married couples participated in the time-limited therapy. They completed a questionnaire on adult attachment and also a self-report questionnaire to assess the effectiveness of the therapy. Narrative analysis was used to assess the praxis or the experience of participating in the therapy. The results show that the integrated model provided a treatment method for differing expressions of marital disturbance and psychopathology. Three of the five couples and eight of the ten participants reported positive treatment outcomes. The research sample included the paraphilias, a major depressive episode with postpartum psychosis, the narcissistic borderline syndrome and childhood sexual abuse. The study supports the association between the role of adult attachment styles and intrapsychic responses in conflicted intimate relationships. From the point of view of clinical applications of attachment theory, the research highlights how theoretical ideas can be integrated, specific clinical methods can be incorporated and certain treatment perspectives can be derived from one another. Several implications for the treatment process flow from this integration. The integration of attachment theory in BCMT demonstrates how the therapeutic process progressed through three separate yet interrelated stages: past, present and future. In addition, it led to the identification of three stage-related mourning processes associated with the time-limited therapeutic process: protest, despair and detachment. From a clinical perspective, the research finds that the theoretical and treatment model does not need to be restricted to marital therapy. The findings suggest that the integrated model could be applied across a wide range of presenting issues. By defining the theory of personality and psychopathology and the therapeutic change processes associated with it, the integration of attachment theory results in BCMT taking its place in the literature as a theory of psychotherapy.
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Lukášová, Pavlína. "Cloud Computing jako nástroj BCM". Master's thesis, Vysoká škola ekonomická v Praze, 2010. http://www.nusl.cz/ntk/nusl-75556.
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This thesis deals with possible interconnections between two concepts playing a big role in contemporary business and IT world. These concepts are Business Continuity Management and Cloud Computing. In the scope of this thesis there are certain areas identified where both concepts are complement, where Cloud Computing brings new opportunities for Business Continuity Management and where could possible problems arise during particular implementation. From the BCM perspective the impact lies on IT services, from the Cloud Computing perspective the thesis deals especially with security aspects. The thesis is also aimed at the characteristics of higher education and basic differences from commercial sphere. Based on defined differences and identified interconnections between BCM and Cloud Computing, the thesis argues for usage of suitable Cloud Computing solution for higher education regarding Business Continuity improvement. The multi-criterion comparison of several Infrastructure-as-a-Service solutions stems from this analysis focusing on technical, financial, and Business Continuity aspects. The result from this comparison together with conclusions from previous chapters serve as an input for subsequent practical proposal of Cloud Computing solution and its verification against Business Continuity improvement in specific conditions on University of Economics in Prague. The proposal is also represented by strategic map.
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Thomson, Emily (Emily S. ). "Thin film BCZT in a capacitive thermo-electric converter". Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/104146.
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Thesis: S.B., Massachusetts Institute of Technology, Department of Materials Science and Engineering, June 2016.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references (page 35).
Thin film BCZT was processed, optimized, and analyzed from powder to ceramic to film for use in a capacitive thermos-electric converter. The idea of using a temperature dependent dielectric to turn heat into electricity has been around for several decades but has never been feasible due to low efficiency and the practical difficulty of being able to thermally cycle the dielectric material quickly enough. However, thin film materials are able to be thermally cycled at high enough frequencies. One material that has potential to be used as the dielectric in a capacitive thermo-electric converter is Ba(TixZr1-x)O3-(BayCa1-y)TiO3. Known as BCZT, this perovskite has previously been studied as an alternative to piezo electrics which are traditionally made with lead. BCZT has a very high dielectric constant of several thousand and, because of its triple point just above room temperature, the dielectric constant is temperature dependent around room temperature. In this paper, BCZT is studied for its potential as a thin film dielectric material in a capacitive thermo-electric converter. Several different compositions around the triple point are created from powder sources, sintered into targets for PLD, analyzed, and the most promising composition was deposited into a thin film and patterned with in-plane capacitor contacts. Analysis using XRD and dielectric measurements was done at several stages.
by Emily Thomson.
S.B.
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Silva, Madson Rubem Oliveira. "Buraco negros, correspond?ncia AdS/BCFT e fluido/gravidade". Universidade Federal do Rio Grande do Norte, 2015. http://repositorio.ufrn.br/handle/123456789/20103.
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Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES
A equa??o de Einstein com constante cosmol?gica negativa gera um espa?o-tempo d + 1?dimens?es, que denominamos de espa?o anti de Sitter, AdSd+1, que nos referimos de "bulk". O principio hologr?fico afirma que a gravidade qu?ntica sobre o AdSd+1 ? codificada por uma teoria de contorno, uma CFTd. Por exemplo, uma teoria de cordas IIB sobre uma espa?o-tempo assintoticamente AdS5 ? S 5 ? dual a uma teoria de gauge de super Yang-Mills N = 4 SYM no espa?o-tempo de 4?dimens?es. Outro exemplo ? a rela- ??o entre a equa??o de Einstein no "bulk"e a equa??o hidrodin?mica descreve uma teoria efetiva no contorno, o qual denominamos de fluido/gravita??o. Uma extens?o da dualidadeAdS/CFT foi proposta por Takayanagi que denominou de correspond?ncia AdS/BCFT. O contorno do CFT extende-se para o "bulk"e restringe o AdSd+1. Quando impomos a condi??o de Neumann sobre a extens?o do contorno obtemos uma equa??o de movimento din?mica que determina a forma da extens?o. Da perspectiva da correspond?ncia fluido/gravita??o o tensor energia-momento do fluido residindo no contorno ser? a fonte da geometria do "bulk". Ampliando a proposta de Takayanagi para correspond?ncia fluido/gravita??o estudaremos a consist?ncia do AdS/BCFT a temperatura finita ou equivalentemente a geometria de BH no "bulk".
Einstein?s equations with negative cosmological constant possess the so-called anti de Sitter space, AdSd+1, as one of its solutions. We will later refer to this space as to the "bulk". The holographic principle states that quantum gravity in the AdSd+1 space can be encoded by a d?dimensional quantum field theory on the boundary of AdSd+1 space, invariant under conformal transformations, a CFTd. In the most famous example, the precise statement is the duality of the type IIB string theory in the space AdS5 ? S 5 and the 4?dimensional N = 4 supersymmetric Yang-Mills theory. Another example is provided by a relation between Einstein?s equations in the bulk and hydrodynamic equations describing the effective theory on the boundary, the so-called fluid/gravity correspondence. An extension of the "AdS/CFT duality"for the CFT?s with boundary was proposed by Takayanagi, which was dubbed the AdS/BCFT correspondence. The boundary of a CFT extends to the bulk and restricts a region of the AdSd+1. Neumann conditions imposed on the extension of the boundary yield a dynamic equation that determines the shape of the extension. From the perspective of fluid/gravity correspondence, the shape of the Neumann boundary, and the geometry of the bulk is sourced by the energy-momentum tensor T?? of a fluid residing on this boundary. Clarifying the relation of the Takayanagi?s proposal to the fluid/gravity correspondence, we will study the consistence of the AdS/BCFT with finite temperature CFT?s, or equivalently black hole geometries in the bulk.
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Cihlářová, Aneta. "Aplikace metod BCM do havarijního plánování". Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-17797.
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Enterprises during their operation are impacted many threats and risks that could dramatically affect their business. Business Continuity Management has evolved to provide resistance against the eternal operational risks. BCM aims to ensure business continuity in case of its danger. The goal of this thesis is to apply the selected methods of the BCM into emergency planning, which is regulated by legislatively for businesses in the Czech Republic.
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Turnbull, Stephen Allan. "Impact evaluation of the applied operations management program at BCIT". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0002/MQ41820.pdf.
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Ljepavic, Danijela. "Les expressions figées en français et en BCMS : traduction, comparaison". Thesis, Strasbourg, 2015. http://www.theses.fr/2015STRAC013.
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Cette thèse procède à une comparaison des expressions figées entre les langues BCMS (bosniaque/bosnien, croate, monténégrin, serbe) et le français en vue de la traduction. Dans la première partie, l'étude commence par la définition des expressions figées et des critères de figement. Après avoir fait le point sur la question des langues BCMS, on présente le corpus des expressions figées en BCMS et en français, avec leur répartition dans différents domaines culturels et la distinction de trois types d'expressions : calques, expressions transparentes, expressions opaques. La seconde partie est consacrée à l'analyse comparative des expressions figées en BCMS et en français. Elle commence par un parcours de leurs différentes origines, puis on examine les fondements culturels des expressions figées, en fonction de différents domaines fournisseurs. On développe ensuite une analyse linguistique comparée des expressions figées, en détaillant les noms composés et les différentes locutions (verbales, adjectivales etc.) et en intégrant la dimension rhétorique, notamment les métaphores. Pour finir, après une mise au point générale sur la traduction, on examine les problèmes d'interprétation et les différentes solutions de traduction des expressions figées dans les deux sens, entre français et BCMSThis thesis makes a comparison between the idioms of the BCMS languages (Bosnian, Croatian, Montenegrin, Serbian) on the one side, and the French language on the other, in the domain of translation.In the first segment, the study begins with the definition of idioms and the criteria for fixation. After the explanation of differences among BCMS languages, we present the corpus of idioms in BCMS and in French, with their distribution within different cultural domains, while distinguishing among three types of idiomatic expressions: literal, transparent, and opaque.The second part is devoted to the comparative analysis of idioms in BCMS and French. It begins with a record of their different origins, after which we examine the cultural foundations of expressions, depending on different domains. We develop a comparative linguistic analysis of idioms, giving details on various compound names and phrases (verbal, adjectival, etc.), and integrating the rhetorical dimension, including metaphors. Finally, after an overall focus on translating, we examine issues found in interpretation and translation solutions for different idioms between French and BCMS
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Natale, Louis, i Craig Wierzbicki. "The BCT-302 1553 Test Bus Card". International Foundation for Telemetering, 2013. http://hdl.handle.net/10150/579706.
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ITC/USA 2013 Conference Proceedings / The Forty-Ninth Annual International Telemetering Conference and Technical Exhibition / October 21-24, 2013 / Bally's Hotel & Convention Center, Las Vegas, NVThe desire to control an LRU and/or MIL-STD 1760 store via an independent 1553 stream on current weapon platforms created the need for the development of the BCT-302 1553 Test Bus Card. This solution solves the issues of integration without the need to perform an aircraft OFP change. The BCT- 302 is a customized MIL-STD-1553 card for use in Teletronics Technology Corporation, (TTC), Airborne Instrumentation Multiplexer (AIM) and High-Speed Avionics Data Acquisition Unit (HSAVDAU) products. The BCT-302 card consists of two redundant MIL-STD-1553 ports. Each port is independently configurable by the AIM/HSAVDAU host processor to function as a Bus Controller (BC), Remote Terminal (RT) or Bus Monitor (BM). The system is capable of cherry picking parameters from any 1553 bus and retransmitting assembled messages to a weapon and/or an LRU in a 1553 format. This paper describes the design requirements of the BCT card and how those requirements were met during an AIM-9X launch on an F-22.
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Fojtík, Ondřej. "Příprava a optimalizace piezoelektrických materiálů na bázi BCZT pro energy harvesting". Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2019. http://www.nusl.cz/ntk/nusl-401844.
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This thesis deals with fabrication and optimization of lead-free piezoceramics based on (Ba0,85Ca0,15Zr0,1Ti0,9)O3 (BCZT). The BCZT precursor powder was synthesized by sol-gel method. Dependence of relative density, microstructure, phase structure and piezoelectric properties on the sintering temperature in a range from 1300–1500 °C was studied on disc shaped samples, which were prepared by cold isostatic pressing (CIP) using pressure of 700 MPa. It was found, that sintering at 1300 and 1350 °C leads to ceramics with fine-grain microstructure, which exhibits poor piezoelectric properties (d*33 = 50 pC·N1 and 65 pC·N1, respectively). The highest value of piezoelectric charge coefficient was obtained by sintering at 1500 °C (d*33 = 390 pC·N1). Furthermore, BCZT thick films were prepared by tape casting. The composition of the ceramic slurry was optimized and various sintering techniques were tested to obtain completely flat films of BCZT ceramics. The correct sintering configuration has not been found. The least deformation of the films was achieved when the samples were sintered hung on the ZrO2 rod. The highest value of d*33 for BCZT films was measured when the sample was sintered at 1400 °C with the dwell time for 4 h (d*33 = 340 pC·N1).
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Lee, L. S. H. "APRIL based therapeutic strategies to target BCMA and TACI in multiple myeloma". Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/1560082/.
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Myeloma remains largely incurable and there is an unmet need for new therapies. B-cell maturation antigen (BCMA) is an attractive therapeutic target due to its restricted expression on normal and malignant plasma cells(PC). A natural ligand for BCMA is a proliferating ligand (APRIL) which also naturally binds another antigen expressed on myeloma cells: Transmembrane activator and CAML interactor (TACI). APRIL is an attractive binder as it is a compact, self-protein which binds both BCMA and TACI with high affinity. BCMA and TACI expression was quantified on tumour cells from a large number of patients to explore the clinical utility of targeting these antigens. Tumour BCMA expression was found in all patients, persisted with relapse and extramedullary spread and low levels was associated with improved patient outcome. However BCMA expression was variable, often low and TACI was co-expressed on tumour from 78% of patients. Recognising that dual antigen targeting of BCMA and TACI may increase target antigens on tumour and reduce the risk of antigen negative disease escape, an APRIL based chimeric antigen receptor(ACAR) was optimised and in vitro activity against BCMA and TACI targets demonstrated. Target kill was seen at low levels of antigen and low effector to target ratios and further, potent ACAR efficacy was demonstrated in vivo in an intramedullary murine myeloma model. A targeted mutagenesis strategy was also used to generate a BCMA specific APRIL mutant. When APRIL mutant was used in a CAR(ACAR-mut), specificity was confirmed for BCMA targets, however there was no significant T cell expansion against primary tumour. In a second strategy, APRIL based bispecific molecules were engineered consisting of a CD3 specific single chain variable fragment linked to an APRILWT(APRILiTE). Preliminary studies using unpurified and unquantified protein in co-cultures of target and activated T cells, demonstrated cytolysis of BCMA expressing cells and primary myeloma cells using APRILiTE. Therefore, APRIL based therapeutic strategies provide a novel and promising approach to immunotherapy in myeloma.
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Doyle, Mary Davis. "Impact of the Bar Code Medication Administration (BCMA) System on Medication Administration Errors". Diss., Tucson, Arizona : University of Arizona, 2005. http://etd.library.arizona.edu/etd/GetFileServlet?file=file:///data1/pdf/etd/azu%5Fetd%5F1093%5F1%5Fm.pdf&type=application/pdf.
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Roussel, Jérôme. "Etude fonctionnelle d'un nouveau membre de la famille des récepteurs au TNF : bcma". Paris 5, 1999. http://www.theses.fr/1999PA05P097.
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Al-Thawadi, Hamda. "Microparticles Mediated Cross-Talk Between Tumoral And Endothelial Cells". Thesis, Université Paris-Saclay (ComUE), 2015. http://www.theses.fr/2015SACLS105.
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Ces dernières années le rôle du stroma tumoral (microenvironnement) dans la progression tumorale. De même le rôle des cellules endothéliales et de la néo-angiogenèse a été illustré dans de multiples études conduisant à la mise en place des thérapeutiques anti-angiogéniques. Cependant il est possible qu’au delà de leur simple rôle comme transporteur d’oxygène et de nutriments les cellules endothéliales jouent un véritable rôle dans la biologie tumorale en sécrétant des substances bioactives (cytokines, microparticules…). Ces médiateurs sont les acteurs actifs d’un dialogue entre cellules tumorales et cellules du stroma. Dans ce travail de thèse nous nous sommes intéressés au rôle particulier des microparticules. Nous avons pu montrer que les microparticules des cellules endothéliales avaient un effet pro-tumoral sur les cellules des cancers de l’ovaire et du sein. Elles étaient capable d’induire une tradition epithélio-mésenchymateuse. Dans la seconde étude nous avons montré que les cellules tumorales sécrétaient des microparticules capable d’activer la voie de signalisation ont/beta-catenin dans les cellules endothéliales par le recrutement de Rac1 et PAKIn our study, we showed that microparticles participate to a complex dialogue between cancer and ECs. Our main finding showed the ability of MPs mediated cross-talk between cancer and ECs to functionalize an activated angiocrine pro-tumoral endothelial niche. Using endothelial Akt activation as a readout, we were able to differentiate MPs from cells with mesenchymal from cells with epithelial traits. Our data showed that MPs from mesenchymal-like cell lines were able to promote an activation of ECs through Akt phosphorylation, compared to MPs from epithelial-like cell lines. The overexpression of Arf6 in activated ECs is associated with quantitative changes of EC-MPs. Additionally, we were interested in determining the mechanisms that derive the activation of ECs toward supporting tumor growth and expansion. Here we showed that ovarian cancer MPs trigger β-catenin activation in ECs by inducing the upregulation of Wnt/bcatenin target genes and increasing the angiogenic proprieties. Interestingly, the activation of bcatenin in ECs was Wnt/Frizzled independent; but dependent on VE-cadherin localization disruption, bcatenin integrin activation and MMP activity
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Le, Cocq Kate Frances. "Engineering the biological control and plant growth promotion fitness of Trichoderma hamatum GD12 through genetic manipulation". Thesis, University of Exeter, 2012. http://hdl.handle.net/10036/4161.
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Trichoderma species are ubiquitous soil saprotrophs and well-characterized biological control agents. Certain strains have also been shown to stimulate plant growth through the production of bioactive secondary metabolites, and are therefore receiving increased attention as natural plant growth stimulants. Previous research at the University of Exeter (Ryder et al. (2012) Microbiology 158, 84-97) has shown that the Plant Growth Promotion activity of a biocontrol strain of Trichoderma hamatum (strain GD12) can be dramatically enhanced by targeted mutation of the N-acetyl-β-D-glucosaminidase-encoding gene nag. However, due to the loss in chitinase activities, the mutant (ΔThnag::hph) displays loss of saprotrophic competitiveness and reduced fitness as a biocontrol agent. We set out to investigate how we can use genetic manipulation to improve strain GD12 in the context of biological control and plant growth promotion. We approached this by firstly sequencing the whole genome of GD12 and then using the information available from this to produce a targeted deletion mutant in the GD12 background disrupting one of the most down regulated proteins in the ΔThnag::hph, a branched chain amino acid transaminase (bcat), implicated in the production of secondary metabolites. Secondly, we aimed to engineer hyper-secretion and enhanced PGP activities in GD12 without impairing biocontrol activity. Over-expression of the S. cerevisiae gene dolichol-phosphate mannose synthase (dpm1) in T. reesei leads to altered cell wall architecture and increased secretory potential. Using the constitutive promoter ToxA, we over-expressed the dpm1 gene in T. hamatum GD12 and assessed its effects on the biocontrol and PGP activities of the fungus. The data presented herein, shows, that bcat deletion in T. hamatum GD12 results in a detrimental effect of germination of lettuce seedlings grown in the presence of ∆Thbcat::hph. We show that single copy insertions of ToxA-dpm1 leads to improved PGP activities, while biocontrol fitness is unaffected. However, while multiple copy insertions similarly lead to enhanced PGP, such strains display impaired biocontrol of soil-borne pathogens such as the plurivorous damping-off pathogen Sclerotinia sclerotiorum. This work demonstrates that while significant improvements in crop productivity can be achieved through genetic modification of the beneficial rhizosphere fungus T. hamatum GD12, it can have important consequences for other aspects of its biology and ecology and competence as a soil-borne microorganism.
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Acquaviva, Laura. "Soluzione del modello di apprendimento BCM in presenza di ambiente generalizzato". Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2016. http://amslaurea.unibo.it/10300/.
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In questa tesi viene illustrato il modello BCM, formulato nel 1982 con l'intento di spiegare il fenomeno di apprendimento neuronale, definito come "plasticita sinaptica".
Si passa successivamente ad una descrizione dettagliata del comportamento di un singolo neurone, per poi estendere la trattazione alle reti neuronali.
L'esposizione degli argomenti viene effettuata considerando cellule esposte a distribuzioni di input linearmente indipendenti.
Viene proposto infine un metodo per adattare il modello al caso linearmente dipendente.
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Wong, W. N. Z. "A critical evaluation of business continuity management (BCM) in UK financial organisations". Thesis, University of Salford, 2007. http://usir.salford.ac.uk/14901/.
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The U.K. financial sector, being the largest contributor to the national economy, needs to have robust contingency arrangements to counter any major operational disruption. As such, this doctoral research identified the premise of the need to raise the status of BCM in financial organisations.
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Lawlor, Matthew. "Tensor Decomposition by Modified BCM Neurons Finds Mixture Means Through Input Triplets". Thesis, Yale University, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=3580742.
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Laurent, Sarah [Verfasser], i Edgar [Akademischer Betreuer] Meinl. "Gamma-secretase directly sheds the survival receptor BCMA from plasma cells / Sarah Laurent. Betreuer: Edgar Meinl". München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2015. http://d-nb.info/1078852014/34.
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Šunka, Pavel. "Aplikace FPGA v řízení maticových displejů LED". Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2018. http://www.nusl.cz/ntk/nusl-376970.
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The thesis gives an overview of the issue of control of full-color RGB LED panels with a large number of rows and columns. It deals with communication protocols for image transfer and information exchange. It focuses on implementing the FPGA into the RGB LED control structure. In the first half, the thesis focuses on deepening the theoretical knowledge about LED technologies, their control and color display. It further solves communication with superior elements. The last part of the theory is dedicated to FPGA circuits. The second part of the thesis describes the practical design of the FPGA circuit from UART and SPI communication through data storage from the communication to the panel control itself.
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Fakir, Kiran. "The use of competitive intelligence in the sustainability of SMMEs in the Buffalo City Metropolitan Municipality (BCMM)". Thesis, Nelson Mandela Metropolitan University, 2017. http://hdl.handle.net/10948/15182.
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The Buffalo City Metropolitan Municipality (BCMM), situated in the second largest province in South Africa, the Eastern Cape, is an unfortunate victim of low economic development and high unemployment. The South African Government, through the Department of Trade and Industry, identified the need for SMMEs to address these issues with the inception of the White Paper on National Strategy for the Development and Promotion of Small Business in South Africa over 20 years ago. SMMEs in South Africa are noted to have a failure rate of around 70% which does not bode well for the efforts to improve economic development and reduce unemployment through SMMEs. This research sets out to determine the significance of variables such as human resources, financial resources, information systems, government assistance and competitive intelligence on the sustainability of SMMEs. The researcher examined the literature relating to the challenges and issues faced by SMMEs with particular emphasis on the use of competitive intelligence as a tool to assist in sustainability. The literature review was followed by an analysis and interpretation of a qualitative study of SMMEs within the BCMM. Through an analysis of the results it was possible to determine the nature of the relationships between the independent variables and sustainability. Finally, the researcher was able to make recommendations based on the research.
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Vusovic, Olivera. "La langue du droit de l'Union européenne : étude linguistique comparée et traduction en français et en BCMS". Thesis, Strasbourg, 2016. http://www.theses.fr/2016STRAC002.
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On effectue une analyse de la langue du droit de l’Union européenne (UE), en comparant, dans une visée contrastive, les tournures et structures caractéristiques du français avec celles du BCMS, et on aborde certaines problématiques liées à la traduction des textes juridiques de l’UE dans cette langue autrefois dénommée serbo-croate, et aujourd’hui connue sous un sigle reprenant les initiales des dénominations : bosniaque, croate, monténégrin et serbe. Cette étude se fonde sur une approche analytique d’un corpus parallèle constitué de quatre versions linguistiques (anglaise, française, croate et monténégrine) de l’Accord de stabilisation et d’association entre les Communautés européennes et leurs États membres d’une part, et la République du Monténégro, d’autre part. Ce document se rattache au droit conventionnel de l’UE et constitue le pilier du processus de stabilisation et d’association dans le cadre duquel s’effectue l’intégration des pays des Balkans occidentaux au sein de l’UEWe analyse EU legal language, compare and contrast French characteristic structures with those of BCMS and examine problems related to the translation of EU legal texts into this language, formerly named Serbo-Croatian and today known by the initials of the names: Bosnian, Croatian, Montenegrin and Serbian. This research is based on an analytical approach to a parallel corpus consisting of four language versions (English, French, Croatian and Montenegrin) of the Stabilisation and Association Agreement between the European Communities and their Member States, of the one part, and the Republic of Montenegro, of the other part. This document is part of the EU’s international agreements which is a pillar of the Stabilisation and Association process, the framework for the integration of Western Balkan countries into the EU
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Santos, Jerre Cristiano Alves dos. "Estudo do comportamento PTCR em cerâmicas de BCT dopadas com íons terra raras". Universidade Federal de Sergipe, 2012. https://ri.ufs.br/handle/riufs/5346.
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Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorBarium titanate (BaTiO3 - BT) is a ferroelectric material with important technological applications. When partially doped with trivalent cations at the barium sublattice or pentavalent at the titanium sublattice, BaTiO3-based ceramics exhibit a semiconductive character, accompanied by a Positive Temperature Coefficient of Resistivity (PTCR). Several ways of BT modifications have been proposed in literature, as example, the use of different synthesis methods and the doping with different ions. Therefore, in the present work we have as objective the synthesis, sintering and electrical characterization of the rare earth ions (RE = La3+, Y3+, Er3+, Nd3+ e Eu3+) doped barium calcium titanate ceramics (Ba0,77Ca0,227RE0,003TiO3 BCT_RE) in order to study mainly the PTCR behavior. The powder synthesis was done by the polymeric precursor method followed by the sinterization at reducing atmosphere during the heating up ramp and different atmosphere during cooling down ramp in order to investigate the atmosphere and dopant effect on PTCR behavior. The characterization was done using the Differential Thermal Analysis, Thermogravimetry, Scanning Differential Calorimetry, X-ray Powder Diffraction, Scanning Electron Microscopy and Impedance Spectroscopy techniques. The calcined powder at 600ºC/4h presented majority BCT phase and after sintering at 1350ºC/6h, a small amount of Ba6Ti17O40 phase was observed. The sintered ceramics presented a homogeneous grain size distribution but with the presence of a secondary phase at the grain boundary for all compositions, and Curie temperature at about 120ºC. The PTCR characteristics of the ceramics were studied as a function of the sintering atmosphere and dopant type. In summary, all the samples, exception of the Eu doped samples, presented PTCR behavior in all the studied conditions. .
O titanato de bário (BaTiO3 - BT) é um material ferroelétrico com importantes aplicações tecnológicas. Quando dopado com íons trivalentes no sítio do bário ou pentavalentes no sítio do titânio, cerâmicas de BaTiO3 exibem um caráter semicondutor, acompanhado por um coeficiente positivo da resistência com o aumento da temperatura (PTCR). Diversas formas de modificação do BT têm sido sugeridas na literatura, por exemplo, a utilização de diferentes métodos de síntese e a dopagem com diferentes íons. Dessa forma, no presente trabalho tivemos como objetivo a síntese, a sinterização e a caracterização elétrica de cerâmicas de titanato de bário e cálcio (Ba0,77Ca0,227RE0,003TiO3 BCT_RE) dopados com íons terras raras (RE = La3+, Y3+, Er3+, Nd3+ e Eu3+), visando principalmente o estudo do comportamento PTCR. A síntese dos pós foi realizada pelo método dos precursores poliméricos, seguido pela sinterização em atmosfera redutora durante o aquecimento e diferentes atmosferas no resfriamento com o intuito de investigar a influência da atmosfera e do dopante no comportamento PTCR. A caracterização foi feita utilizando as técnicas de Análise Térmica Diferencial, Termogravimetria, Calorimetria Exploratória Diferencial, Difração de Raios X, Microscopia Eletrônica de Varredura e Espectroscopia de Impedância. Os pós calcinados a 600ºC/4h apresentaram fase majoritária BCT e após sinterizados a 1350ºC/6h foi observada a presença da fase Ba6Ti17O40. As cerâmicas sinterizadas apresentaram uma distribuição homogênea de tamanho de grão, porém com a presença de uma segunda fase na região de contorno de grão para todas as composições, com temperatura de Curie em torno de 120ºC. As características PTCR das cerâmicas foram estudadas em função da atmosfera de sinterização e do tipo do dopante. Em resumo, todas as amostras, com exceção das dopadas com Eu, apresentaram comportamento PTCR para todas as condições estudadas.
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Girod, Thomas. "Un modèle d'apprentissage multimodal pour un substrat distribué d'inspiration corticale". Phd thesis, Université Henri Poincaré - Nancy I, 2010. http://tel.archives-ouvertes.fr/tel-00547941.
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Le domaine des neurosciences computationnelles s'intéresse à la modélisation des fonctions cognitives à travers des modèles numériques bio-inspirés. Dans cette thèse, nous nous intéressons en particulier à l'apprentissage dans un contexte multimodal, c'est à dire à la formation de représentations cohérentes à partir de plusieurs modalités sensorielles et/ou motrices. Notre modèle s'inspire du cortex cérébral, lieu supposé de la fusion multimodale dans le cerveau, et le représente à une échelle mésoscopique par des colonnes corticales regroupées en cartes et des projections axoniques entre ces cartes. Pour effectuer nos simulations, nous proposons une bibliothèque simplifiant la construction et l'évaluation de modèles mésoscopiques. Notre modèle d'apprentissage se base sur le modèle BCM (Bienenstock-Cooper-Munro), qui propose un algorithme d'apprentissage non-supervisé local (une unité apprend à partir de ses entrées de manière autonome) et biologiquement plausible. Nous adaptons BCM en introduisant la notion d'apprentissage guidé, un moyen de biaiser la convergence de l'apprentissage BCM en faveur d'un stimulus choisi. Puis, nous mettons ce mécanisme à profit pour effectuer un co-apprentissage entre plusieurs modalités. Grâce au co-apprentissage, les sélectivités développées sur chaque modalité tendent à représenter le même phénomène, perçu à travers différentes modalités, élaborant ainsi une représentation multimodale cohérente dudit phénomène.
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Celtikci, Baris. "Preparation Of Lead-free Bzt-bct Thin Films By Chemical Solution Deposition And Their Characterization". Master's thesis, METU, 2012. http://etd.lib.metu.edu.tr/upload/12614623/index.pdf.
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In the presented thesis, lead-free Ba(Ti0.8Zr0.2)O3-(Ba0.7Ca0.3)TiO3 (BZT-BCT) thin films were deposited on Pt/TiO2/SiO2/Si substrates using chemical solution deposition method and then the effect of process parameters were investigated to obtain optimum parameters of these lead-free thin films. The phase was selected near to the morphotropic phase boundary (MPH) to increase the number of polarization directions where rhombohedral and tetragonal phases exist together.
In this study, the effect of sintering temperatures on microstructure, dielectric and ferroelectric properties were studied systematically. Among the various high-quality BZT-BCT thin films with uniform thickness, the optimum dielectric and ferroelectric responses were observed for films annealed at 800 oC for 1 h sintering time. The thickness was kept constant for all measurements as 500 nm (triple layered films). Therefore, the average grain sizes were found around 60 nm for samples sintered at 700,750 and 800 oC.
BZT-BCT thin films sintered at 800 oC showed effective remnant polarization and coercive field values of 2.9 µC/cm2 and 49.4 kV/cm, together with a high dielectric constant and low loss tangent of 365.6 and 3.52 %, respectively, at a frequency of 600 kHz due to pure perovskite phase showing full crystallization and minimum surface porosity obtained at this temperature.
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Pandolfi, Sara. "Studio dell’invecchiamento dei sensori di Beam Condition Monitoring System dell’esperimento ALICE". Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2020. http://amslaurea.unibo.it/21884/.
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Questa tesi si propone di studiare l’invecchiamento dei sensori che compongono il Beam Condition Monitor System (BCM), il sistema di protezione di ALICE da eventuali problematiche legate al fascio di particelle, come i beam failures o beam losses. ALICE (A Large Ion Collider Experiment) è uno dei grandi esperimenti presenti ad LHC (Large Hadron Collider) presso il CERN di Ginevra, dedicato allo studio delle proprietà dello stato della materia chiamato Quark Gluon Plasma (QGP). Per riuscire in questo studio, ALICE si serve di una grande quantità di dati raccolti durante collisioni tra ioni pesanti di piombo (Pb) e protoni. ALICE è composto da numerosi e sofisticati rivelatori, alcuni dei quali posti in prossimità del fascio di particelle. Ogni rivelatore che compone l’esperimento è dedicato alla misura di un particolare segnale fisico o di una caratteristica della collisione analizzata. Il danneggiamento di anche solo uno di tali rivelatori potrebbe quindi limitare le performance di tutto l’esperimento, o addirittura arrestare la presa dati. I detector sono progettati per essere estremamente sensibili alle particelle che vengono generate nelle collisioni studiate: risultano così vulnerabili alle imperfezioni che si possono presentare nel fascio o nella sua iniezione nell’anello di LHC dopo essere stato accelerato dai precedenti acceleratori. Il sistema di protezione dal fascio presso ALICE è dato da una combinazione di "hardware interlocks" che compongono il Beam Interlock System (BIS) di LHC e del Beam Condition Monitor System. Le analisi effettuate in questa tesi, che hanno come oggetto di studio la risposta degli 8 sensori al diamante pCVD che compongono la Stazione 0 del BCM in funzione della luminosità dell’esperimento, hanno permesso di evidenziare come la risposta dei sensori sia variata negli anni, indicando quindi un loro invecchiamento.
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Pessoa, Marcos Cézar Fernandes. "Caracterização genotípica e sequenciamento de enterotoxinas (HBL, NHE e BceT) de linhagens de B. thuringiensis isoladas no estado do Amazonas". Universidade Federal do Amazonas, 2009. http://tede.ufam.edu.br/handle/tede/4381.
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Bacillus thuringiensis is a Gram-positive bacterium commonly used in the tropical disease vectors and agriculture pragues control. Despite of its use both agriculture and human health, this bacterium can be enterotoxins producer that are also present in a few Bacillus cereus strains, emphasizing the non-haemolytic enterotoxin (NHE), haemolysin BL (HBL) and enterotoxin T (BceT) that have been related to food poisoning outbreaks reported in the literature. Thereby, this work had as a purpose to identify and to realize a genotypic characterization of these enterotoxins in one hundred B. thuringiensis strains isolated in the Amazon State, as well as to achieve the sequencing of these enterotoxin genes starting from the product of Polymerase Chain Reaction (PCR). The prevalence of these enterotoxin genes in B. thuringiensis strains by PCR method was relatively high, of which the results for the seven genes researched (bceT, hblA, hblD, hblC, nheA, nheB and nheC) showed different between themselves. By the genotypic profile were determined 27 groups and was evidenciated that 41% of the strains were positives for all the enterotoxin genes, whereas 3% were negatives for all the genes studied.. The analysis of the nucleotides and amino acids sequences of the Amazonian B. thuringiensis strains identified similarities with the nucleotides and amino acids sequences that are deposited in the GenBank and EMBL databases.
Bacillus thuringiensis é uma bactéria Gram-positiva comumente utilizada no controle de vetores de doenças tropicais e pragas da agricultura. Apesar de seu uso tanto na agricultura quanto em saúde humana, esta bactéria pode ser produtora de enterotoxinas que estão presentes também em algumas linhagens de Bacillus cereus, destacando-se a enterotoxina não-hemolítica (NHE), a hemolisina BL (HBL) e a enterotoxina T (BceT), que têm sido relacionadas a surtos de intoxicação alimentar relatados na literatura. Em vista disso, este trabalho teve como objetivo identificar e caracterizar genotipicamente estas enterotoxinas em 100 linhagens de B. thuringiensis isoladas no Estado do Amazonas, bem como realizar o seqüenciamento destes genes de enterotoxinas a partir do produto da Reação em Cadeia de Polimerase (PCR). A prevalência dos genes destas enterotoxinas nas estirpes de B. thuringiensis pelo método de PCR foi relativamente alta, cujos resultados para os sete genes pesquisados (bceT, hblA, hblD, hblC, nheA, nheB e nheC) mostraram-se distintos entre si. Pelo perfil genotípico foram determinados 27 grupos e ficou evidenciado que 41% das linhagens deram positivas para todos os genes de enterotoxinas, enquanto que 3% foram negativas para todos os genes estudados. A análise das sequências de nucleotídeos e de aminoácidos das linhagens de B. thuringiensis amazônicas identificou similaridades com as sequências de nucleotídeos e aminoácidos que estão depositadas no banco de dados do GenBank/EMBL.
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Mariani, Tommaso. "Comparison between Oja's and BCM neural networks models in finding useful projections in high-dimensional spaces". Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amslaurea.unibo.it/14512/.
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This thesis presents the concept of a neural network starting from its corresponding biological model, paying particular attention to the learning algorithms proposed by Oja and Bienenstock Cooper & Munro. A brief introduction to Data Analysis is then performed, with particular reference to the Principal Components Analysis and Singular Value Decomposition.
The two previously introduced algorithms are then dealt with more thoroughly, going to study in particular their connections with data analysis. Finally, it is proposed to use the Singular Value Decomposition as a method for obtaining stationary points in the BCM algorithm, in the case of linearly dependent inputs.
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Gomes, Inês Lavado. "Pesquisa de enterotoxinas em isolados alimentares do grupo Bacillus cereus". Bachelor's thesis, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária, 2009. http://hdl.handle.net/10400.5/1239.
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Dissertação de Mestrado Integrado em Medicina VeterináriaOs microrganismos do grupo Bacillus cereus são causadores de patologia gastrointestinal, podendo ocorrer duas formas da doença: a síndrome diarreica e a síndrome emética. A forma diarreica é causada pela presença de enterotoxinas. São várias as enterotoxinas produzidas por B. cereus. Existem duas toxinas tripartidas, a hemolisina BL (HBL) e a enterotoxina não hemolítica (NHE), a citotoxina K (CytK), a enterotoxina T e a enterotoxina FM. Este estudo consistiu na pesquisa de genes que codificam enterotoxinas, por PCR (reacção de polimerase em cadeia) em tempo real, em 76 isolados alimentares, provenientes da colecção de bactérias do Laboratório de Bromatologia e Defesa Biológica do Exército. As bactérias utilizadas neste estudo foram caracterizadas morfologicamente, através do isolamento em MYP e agar sangue, e bioquimicamente utilizando a galeria API 50 CH®. Das 76 estirpes analisadas 28 revelaram-se positivas para a toxina HBL, 27 para a NHE, 43 para a enterotoxina T e nenhuma estirpe foi positiva para a citotoxina K. Em suma, 58 das 76 estirpes de B. cereus sensu lato utilizadas neste trabalho são potencialmente patogénicas. Os resultados obtidos demonstraram a existência de uma grande variabilidade de estirpes B. cereus potencialmente produtoras de enterotoxinas isoladas de alimentos.
ABSTRACT - Many strains of Bacillus cereus group cause gastrointestinal diseases, which include two types: diarrheal and emetic syndromes. The diarrheal type of disease is attributed to enterotoxins. Many enterotoxins are produced by B. cereus. The enterotoxins include two tri-partied toxins, hemolysin BL (HBL) and nonhemolytic enterotoxin (NHE), cytotoxin K, enterotoxin T and finally enterotoxin FM. The primary objective of this study was the detection of gene enterotoxins, by real-time PCR (polimerase chain reaction), produced by 76 strains isolated from food samples. Those strains were included in a bacterial collection from LBDBE. The strains used in this study were characterized based on morphological data, like the presence or absence of haemolysis, and biochemical information, using the test API 50 CH®. 28 strains were positive for toxin HBL, 27 for NHE and 43 were positive to enterotoxin T. None of the strains were positive to cytotoxin K. The results showed a high variability in potencial enterotoxic B. cereus strains isolated from food.
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Xiao, Yanping. "APRIL (TNFSF13) in Th1, Th2 and Th17 Responses". Scholarly Repository, 2009. http://scholarlyrepository.miami.edu/oa_dissertations/335.
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The T cell function of a proliferation inducing ligand (APRIL or TNFSF13) remains unclear. By comparing APRIL-/- mice with wild type (WT) mice, we have investigated the roles of APRIL in Th1, Th2 and Th17 responses. With regard to APRIL in Th1 responses, cultured APRIL-/- CD4+ T cells showed increased IFN-gamma production under non-polarizing, but not under Th1 polarizing, conditions. No difference in antigen-specific IgG2a levels existed between APRIL-/- and WT mice immunized with ovalbumin (OVA) and complete Freund's adjuvant (CFA) which induces Th1 polarization. Our data indicate that APRIL represses Th1 responses only under non-polarizing conditions. As for APRIL in Th2 responses, cultured APRIL-/- CD4+ T cells exhibited enhanced Th2 cytokine production under non-polarizing conditions, and augmented IL-13 production under Th2 polarizing conditions. Upon immunization with OVA and aluminum potassium sulfate (alum) which induces Th2 polarization, APRIL-/- mice responded with an increased antigen-specific IgG1 response. In the OVA-induced allergic lung inflammation model which is mediated by Th2 responses, APRIL-/- mice had significantly aggravated allergic lung inflammation. Accordingly, a decoy receptor-Ig fusion protein, TACI-Ig, treatment to block APRIL in WT mice enhanced allergic lung inflammation. In agreement with the role of APRIL in CD4+ T cells, the transfer of APRIL sufficient, OVA-specific, TCR transgenic CD4+ T (OT-II) cells to APRIL-/- mice restored the suppressive effect of APRIL on allergic lung inflammation. Mechanistically, the expression of c-maf, the IL-4 gene transcription factor, was markedly enhanced in APRIL-/- CD4+ T cells under non-polarizing and Th2 polarizing conditions. Our data suggest that APRIL inhibits Th2 responses and allergic lung inflammation by suppressing IL-4 production in CD4+ T cells via diminished c-maf expression, and by suppressing IL-13 production in CD4+ T cells via an IL-4 independent, IL-13 specific pathway. Regarding APRIL in Th17 responses, the incidence of Th17-mediated collagen-induced arthritis (CIA) in APRIL-/- mice was reduced, in parallel with diminished levels of antigen-specific IgG2a autoantibody and IL-17 production. Our data indicate that APRIL promotes IL-17 production, and that APRIL-triggered signals contribute to arthritis. Our data clearly show that APRIL is important in T cell immunity, inhibitory in Th2 responses and costimulatory in Th17 responses.
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Avanzi, Ariel. "Biophysical model of synaptic plasticity". Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2020. http://amslaurea.unibo.it/21967/.
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Nel 1982 Elie Bienestock, Leon Cooper e Paul Munro scrissero ”Theory for the development of neuron selectivity” proponendo uno schema di evoluzione sinaptica nel quale competono i modelli in arrivo piuttosto che la convergenza degli afferenti. Brevemente divenne nota come teoria BCM e fu il trampolino di lancio per ulteriori lavori sulla modificazione delle sinapsi corticali. Durante le ultime due decadi sono state fatte nuove formulazioni, come la IBCM di Nathan Intrator e Leon Cooper del 1992, e nuovi metodi sono stati introdotti permettendo la creazione di reti neurali più complicate ed efficienti. Lo studio di questi modelli evidenzia la capacità di adattamento a diverse situazioni in un modo semplice. Sono stati fatti studi allevando animali in un periodo critico per lo sviluppo sella selettività corticale e l’accordo tra i dati e la teoria è stato provato. Tutta la teoria, valida per i neuroni corticali, potrebbe essere migliorata con una maggiore capacità di calcolo che permetterebbe di sbarazzarsi di alcune approssimazioni.
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Le, Calvé-Ivičević Évaine. "L'aspect verbal en croate contemporain : étude des valeurs aspectuelles de l'infinitif". Thesis, Paris 4, 2015. http://www.theses.fr/2015PA040114.
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L’évidence morphologique de l'aspect verbal dans les langues slaves en fait un sujet d'étude bien connu, mais ce domaine demeure peu exploré pour ce qui est de la langue croate. Ce travail, qui s'appuie pour l'appareil théorique sur plusieurs travaux traitant de l'aspect verbal et des valeurs aspecto-temporelles en BCMS et dans d'autres langues slaves, complète dans un premier temps les connaissances sur le comportement aspectuel de l'infinitif et dresse une liste de ses valeurs aspectuelles dans toutes ses fonctions, notamment en tant que complément des verbes modaux des domaines sémantiques pouvoir, devoir et vouloir. Au-delà de cette analyse, il offre une série d'algorithmes établis sur les facteurs (im)perfectivants, et permettant de résoudre le problème du choix aspectuel dans de multiples situations données. Posant comme prémisse que les informations contribuant à déterminer les choix et les valeurs de l'aspect sont pour une bonne partie recelées dans le sémantisme du verbe à l'infinitif et le procès qu'il dénote, ce travail explore l'influence des propriétés de la situation référentielle sur le choix aspectuel. Afin d'éviter une confusion entre valeurs aspectuelles et contenus sémantiques, sont traités séparément l'infinitif indépendant, l'infinitif complément de verbes de modalité, puis des verbes modaux. Il s'avère que les facteurs qui motivent le choix de l'aspect des infinitifs sont d'origines différentes et relèvent de la nature de la notion verbale et des propriétés du procès référentiel. En ce qui concerne l'impact du semi-auxiliaire, il n'est lié au choix de l'aspect que dans la mesure où il contribue à créer une situation référentielleDue to its morphological markedness, the verbal aspect in Slavic languages is a well-known subject of study, but this area remains little explored in terms of the Croatian language. This thesis, whose theoretical apparatus is based on several works dealing with the verbal aspect as well as aspectual and temporal values in BCMS and other Slavic languages, completes the knowledge about the behavior of the aspectual infinitive, and lists its aspectual values in all its functions, including a complement of verbs expressing modality, namely, "can", "must" and "want". Together with this analysis, the thesis offers a series of algorithms developed on the factors of (im)perfectivation, which answer the question of aspectual choice in many given situations. Posing as a premise that the information that helps to determine aspectual choices and values is mainly harbored in the semantics of the infinitive and the act it denotes, this thesis explores the influence of referential situation properties on the aspectual choice. To avoid confusion between aspectual values and semantic content, we treated the independent infinitive and infinitive complement of modality or modal verbs separately. The results of the study show that the factors that motivate the choice of infinitives have different origins and deal with the properties of verbal concept and reference situation. The semi-auxiliary verb has some influence only insofar it helps to create a reference situation
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Dancy, Alant'e Jaquan. "Energy Harvesting IC Design for an Electromagnetic Generator Based on the Split Capacitor Approach". Thesis, Virginia Tech, 2018. http://hdl.handle.net/10919/85043.
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The proposed energy harvesting system intends to harvest vibrational energy via an electromagnetic generator (EMG). The proposed circuit intends to extract maximum power from the EMG by utilizing the maximum power transfer theorem which states that maximum power is transferred to the load when the source resistance equals the load resistance. The proposed circuit is a synchronous split-capacitor boost converter operating in boundary conduction mode (BCM) to achieve impedance matching and therefore maximum power transferred to the load. The circuit topology combines the rectifier and power stage to reduce power loss of the power management integrated circuit (PMIC).
The proposed circuit is designed and fabricated in 130 nm BiCMOS technology. The circuit is validated through schematic level simulations and post-layout simulations. The results conclude the proposed circuit and control operates in a manner to achieve BCM.Master of Science
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Laird, Brian. "The development of a reporter system for Bacillus cereus to establish the environmental conditions needed for production of Bacillus cereus enterotoxin T (bceT)". Thesis, University of Strathclyde, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502310.
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Bacillus cereus is primarily a soil-dwelling bacterium, however it is also pathogenic bacterium, which is implicated in many food poisoning outbreaks throughout the world. It is responsible for both non-gastrointestinal and gastrointestinal infection with the former leading to many working days lost. Two types of infection exist, the emetic Infection and the diarrhoeal infection. The emetic infection is caused by a heat stable protein, which causes vomiting and stomach cramps. The diarrhoeal infection is caused by several different toxins including haemolysin BL (HBL), non-haemolytic enterotoxin (NHE), B. cereus enterotoxin T (bceT), cytotoxin K (cytK), the recently discovered Hlyll toxin and enterotoxin Fm (entFM). The purpose of this project was to develop a reporter system that could be used to investigate the environmental conditions necessary for the production of Bacillus cereus enterotoxin T (bceT) after human ingestion. A plasmid was constructed that carried the bceT gene, which would ultimately be integrated Into the B. cereus chromosome after manipulation.
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Laâbi, Yacine. "Analyse moleculaire du gene bcma qui code pour une proteine localisee dans la region cis de l'appareil de golgi des lymphocytes b matures". Paris 7, 1994. http://www.theses.fr/1994PA077259.
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L'analyse moleculaire d'une translocation chromosomique t(4 ;16)(q26 ;p13) associee a un lymphome t intestinal humain a permis d'isoler un adnc hybride resultant de la fusion du gene de l'interleukine 2 avec un nouveau gene localise sur le chromosome 16. Ce gene que nous avons nomme bcma (pour b-cell maturation) est exprime de maniere preferentielle dans la lignee lymphoide b et son taux de transcription semble etre lie au processus de differenciation des lymphocytes b. Nous avons d'une part caracterise l'organisation genomique du gene bcma. Nous avons d'autre part obtenu des anticorps diriges contre la proteine bcma recombinante. Ces anticorps reconnaissent un peptide de 21 kda uniquement dans les lignees lymphoides b matures. La proteine bcma est donc synthetisee in vivo. Nous avons demontre par fractionnement cellulaire, immunoprecipitation et immunofluorescence que la proteine bcma est integree dans la membrane d'un sous-compartiment de l'appareil de golgi. L'analyse par microscopie confocale de la co-localisation ou non de la proteine bcma avec plusieurs marqueurs specifiques des compartiments de cet organite cellulaire indique que la proteine bcma est probablement localisee dans la region cis de l'appareil de golgi des lymphocytes b matures. La proteine bcma est ainsi la premiere proteine a etre decrite qui soit localisee dans l'appareil de golgi et dont l'expression soit preferentielle d'un type cellulaire. Dans le cadre de cette etude, nous avons mis en evidence, par clonage moleculaire, protection a la rnase et slic-pcr, un transcrit antisens aux arnm bcma. Cet arn antisens naturel est exprime tres faiblement dans la majorite des cellules exprimant bcma et contient une phase de lecture ouverte qui coderait pour un polypeptide de 115 acides amines. Le locus bcma est donc transcrit de maniere bidirectionnelle donnant naissance a deux arn polyadenyles, episses et contenant des phases de lecture ouvertes
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Njeru, Jackson Ngigi. "Nursing Approaches for Use and Sustainability of Barcode Medication Administration Technology". ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/4541.
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Approximately 43.4% of medication errors occur at the time of administration despite the use of bar code medication administration (BCMA) System. This trend has prompted a national effort to mitigate this problem in the United States. Implementing BCMA in health care settings is one of those efforts. Studies focusing on the approaches employed by nurses when using this system are scant. The purpose of this qualitative case study was to investigate strategies nurses and their leaders use to ensure BCMA is implemented, maximized, and sustained. The technology acceptance model was used to guide the study. The 2 research questions addressed nurses' perceptions regarding the use and optimization of BCMA, and approaches of clinical nurses and their leaders to ensure that BCMA technology is properly used, optimized, and sustained in acute care units. Data collection included semistructured interviews with 8 participants. Thematic data analysis generated themes including ease of use, reduce errors, time saving, old technology, overreliance on technology, paper backups, and hope for future development. Common barriers to system effectiveness were system errors and inadequate training; intragroup and self-monitoring were important strategies to sustain use of the system. Study results may be used by health care leadership to reduce medication errors by adopting easy to use technology, change policies regarding training of BCMA end users in hospitals, increase the culture of patient safety among nurses, and prompt technology redesign within health care settings that meets the national patient safety goals.
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Coles, Steven John. "Redox regulation through S-thiolation and S-nitrosylation of the BCAT proteins with insights in to the role these systems play in neuronal cells". Thesis, University of the West of England, Bristol, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490456.
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The human mitochondrial and cytosolic branched chain aminotransferases (hBCATm and hBCATc, respectively) are key metabolic enzymes that catalyse the reversible transamination of the nutritionally essential branched-chain amino acids. Both isozymes have a conserved redox active CXXC motif, unique among the mammalian aminotransferases. In the present study the effect of ^S-nitrosylation, iS-thiolation or disulphide bond formation on the functionality of the BCAT proteins was investigated.
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MADRY, CHRISTINE. "La proteine bcma (b cell maturation) est un nouveau membre de la famille des recepteurs au tnf implique dans l'homeostasie de la population lymphocytaire b". Paris 7, 2000. http://www.theses.fr/2000PA077142.
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Le gene bcma (b cell maturation), isole apres analyse moleculaire d'une translocation t(4 ; 16) specifique d'un lymphome t intestinal, est exprime de facon preferentielle dans les lymphocytes b matures. Il code une proteine de 184 acides amines localisee dans une structure perinucleaire. Nous avons realise le clonage d'un adnc bcma murin afin d'obtenir des informations sur le role biologique de la proteine. La comparaison des sequences proteiques bcma humaine et murine revele la conservation de six cysteines dans le domaine terminal. La technique hca (high cluster analysis) indique que ces residus forment un domaine crd, caracteristique de la region extracellulaire des recepteurs au tnf. La proteine bcma constitue donc a un nouveau membre de cette famille (tnfrsf17). Ce recepteur dont l'expression a la surface des cellules b matures est hautement regulee, active des voies de signalisation communes aux autres tnfr : kinases jnk, p38, facteurs de transcription nf-kb, ap1 et elk-i ; via le recrutement de proteines adaptatrices de la famille traf (traf 1, 2 et 3). De plus, il fixe un ligand orphelin de la famille tnf : baff (b cell activating factor belonging to the tnf family). Des etudes realisees in vivo indiquent que le recepteur bcma est implique dans le maintien de l'homeostasie de la population lymphocytaire b, probablement via l'induction de signaux de survie cellulaire. Par ailleurs, les fonctions de la proteine bcma sont regulees de facon negative par un arnm antisens naturel. Ce dernier altere les fonctions du gene sens sous sa forme polynucleotidique, en inhibant la traduction des messagers bcma, ce par un mecanisme impliquant partiellement l'intervention d'une enzyme desaminase. Des etudes complementaires permettront d'affiner nos connaissances sur les mecanismes de regulation du gene. Nos donnees suggerent que la proteine bcma pourrait constituer un outils interessant dans la therapie des pathologies auto-immunes liees a une surproduction de lymphocytes b.
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Giachin, Marco. "Integrazione tra Blockchain e Internet of Things: Implementazione, Sviluppo e Analisi". Master's thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amslaurea.unibo.it/22330/.
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Negli ultimi anni la tecnologia blockchain si è distinta sia per i risultati portati nel campo dello scambio di valore digitale, tramite le criptovalute, sia per la possibilità di utilizzarla come alternativa ai tradizionali strumenti di memorizzazione delle informazioni. Una peculiarità della tecnologia blockchain infatti è quella di conservare le informazioni in “blocchi”, collegati gli uni agli altri tramite tecniche crittografiche; il risultato di questa particolare struttura dati è la possibilità di tracciare tutta la storia di un dato e i suoi scambi, arrivando al punto in cui è stato inserito all’interno del sistema.
Contemporaneamente allo sviluppo della tecnologia blockchain l’IoT ha trovato campo di applicazione in una quantità enorme di applicazioni industriali, al fine di effettuare il monitoraggio e il controllo da remoto o automatico di sistemi elettronici. I dispositivi IoT sono fondamentali per lo sviluppo delle cosiddette smart cities, poiché abilitano l’automazione di tipologie di azioni e controlli che normalmente dovevano essere realizzati in maniera manuale.
La commistione delle due tecnologie sopracitate ha preso il nome di Blockchain of Things (BCoT), e rappresenta l’ultima evoluzione dello scambio informativo tra dispositivi IoT, che sono quindi in grado, oltre che di effettuare operazioni sull’ambiente, anche di certificare i dati raccolti in maniera automatica tramite la blockchain e fornirli all’utente finale all’interno di un ledger decentralizzato (letteralmente “libro mastro”, termine inglese usato per indicare la struttura dati che sostiene una generica blockchain).
Lo scopo di questo elaborato é quindi quello di proporre una soluzione general-purpose che faccia uso della tecnologia BCoT per rispondere ad un insieme di criticità trasversali e riscontrate in vari campi applicativi.
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Waclawska-Krzeminski, Izabela Jadwiga [Verfasser], Christine [Akademischer Betreuer] [Gutachter] Ziegler i Clemens [Gutachter] Glaubitz. "BCCT family : dynamics in stress-regulated betaine transport and role of pathogen-relevant choline transport / Izabela Jadwiga Waclawska-Krzeminski. Betreuer: Christine Ziegler. Gutachter: Clemens Glaubitz ; Christine Ziegler". Frankfurt am Main : Universitätsbibliothek Johann Christian Senckenberg, 2016. http://d-nb.info/1112601171/34.
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Silva, de Farias Carlene Paula. "Competing Orders in URu2Si2 : from ordered magnetism to spin liquid phases". Thesis, Bordeaux, 2017. http://www.theses.fr/2017BORD0569/document.
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L’objectif central de cette thèse est d’étudier des phases ordonnées en compétition dans des matériaux magnétiques présentant une structure cristalline tétragonale centrée.Ce travail est divisé en deux parties principales. Dans la première, nous présentons les résultats de notre étude de la compétition entre des états ordonnés antiferromagnétiques et des phases liquides de spin. Nous montrons comment ces dernières peuvent être stabilisées par la frustration géométrique et par une généralisation de la symétrie de spinau groupe SU(n). Les états antiferromagnétiques sont décrits par une théorie d’onde despin et l’analyse de liquide de spin est effectuée par une représentation fermionique des opérateurs de spin. Dans la deuxième partie, nous décrivons une théorie effective pour dércrire des expériences de diffusion Raman. Nous fournissons un aperçu de la phase d’ordre caché affichée par le composé de fermions lourds URu2Si2The main objective of this thesis is to investigate the competing ordered phases in the metallic heavy fermion compound URu2Si2, which displays a body-centered tetragonallattice. We first provide a study case of the competition between antiferromagnetic(AF) and spin liquid phases. The antiferromagnetic state is study with spin-wave theory. Whereas the spin liquid analysis has been carried out in an algebraic spin liquid representation.In the second part, we describe an effective theory for Raman scattering experiments at these particular phases. We provide insight about the hidden order phase displayed by the heavy fermion compound URu2Si2
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Xu, Yudong. "Energy Harvesting Circuit with Input Matching in Boundary Conduction Mode for Electromagnetic Generators". Thesis, Virginia Tech, 2018. http://hdl.handle.net/10919/85123.
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The proposed circuit intends to harvest kinetic energy from ElectroMagnetic Generators (EMGs). In order to extract maximum power from an EMG, an AC-DC boost rectifier is designed to match the impedance of the EMG. Rather than operate a buck-boost converter in Discontinuous Conduction Mode (DCM) in other impedance matching cases, the proposed method is running the boost topology in Boundary Conduction Mode (BCM). So it would perform resistive input matching, while reducing the converter power loss. The boost rectifier also merges a rectifier and a boost converter to reduce power loss for rectification. It also utilizes the internal inductance of the EMG to eliminate the impedance matching error and reduce the off-chip inductor size. An optional buck converter regulates the output voltage to 5 V to power devices through USB ports.
The proposed circuit is designed and fabricated in BiCMOS 0.18 μm technology. Its functionality is shown through simulation results. The measurement of the IC is also performed. However, since the IC only work partially, test result is gathered using some discrete components as substitutes. It indicates the circuit can realize the proposed control method.Master of Science
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Nashidengo, Pueya Mekondjo. "Five-year review of breast-conserving therapy (BCT) for breast carcinoma: Surgical margins, re-excision and local recurrence in a single tertiary center". Master's thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/24506.
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Background: Breast cancer burden is on the increase in the developing world. Breast-conserving therapy (BCT) is prescribed for early breast cancer. It is the wide local excision of the tumour usually followed by radiation treatment to the breast. It is the mainstay treatment for carefully selected patients with early breast cancer presenting to the Groote Schuur Hospital's Oncology and Endocrine Surgical unit, Cape Town South Africa. There has not been a formal audit to review the outcomes of BCT in the unit. Objectives: The objective of this study is to determine and analyse the excision margins for all the wide local excisions and the re-excision and local recurrence rates during the study period. Methods: This is a histopathological and oncology records review of the patients that have undergone BCT in the unit from the 1st of January 2006 until the 31st of December 2010. The University of Cape Town's Faculty of Health Sciences Human Research Ethics Committee granted approval. Data points accrued included patient age, pathological tumour size and nodal status, histological tumour type, oestrogen receptor status, presence of lymphovascular invasion, volume of specimen excised, margin status, management of involved or close margins, completeness of radiotherapy, ipsilateral breast recurrence rate and total duration of follow up. Results: A total of 192 patients had BCT during the study period. The mean age is 53 years (range 25 to 84 years). A median of 229.5 cm3 volume of specimen was excised (range 4 cm3 to 10530 cm3). Infiltrating ductal carcinoma was the commonest histological type at 79.1%. 42.7% were pT1 tumours, 49.0% pT2 tumours and 2.6 % pT3. The resection margin status are: positive margins rate of 15.1%, 8.3 % close margin (≤ 1 mm), 35.9% 1 – 5 mm, 23.4% 6 – 10 mm and > 10 mm 17.2%. An overall of 26 (13.5%) patients underwent a repeat surgical procedure. 16 (8.3%) had re-excision and 10 (5.2%) had a mastectomy. Residual tumour was present in 50% of the re-excisions and 63.6% of mastectomies. As per category of the resection margins, 68.9% of patients with positive margins had repeat surgery (48.3% re-excision and 20.6% mastectomy). 31.1% of patients with positive margins did not have repeat surgery despite the indication due to advanced age, loss to follow up or residual tumour on the deep chest wall margin. 80.8% patients completed radiotherapy treatment post breast-conserving surgery. At a median follow up of 60 months (range 1 to 108 months), a total of 11 (6.8%) patients had ipsilateral breast local recurrence. Median time to recurrence is 39 months (range 12 to 106 months). Conclusion: Positive and close margin re-excision and local recurrence rates in our unit are acceptable and comparable to other units in South Africa and internationally.
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Li, Xiuli. "Block Copolymer Solutions: Transport and Dynamics, Targeted Cargo Delivery, and Molecular Partitioning and Exchange". Diss., Virginia Tech, 2020. http://hdl.handle.net/10919/104197.
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Block copolymers have been extensively applied in diverse fields including packaging, electrolytes, delivery devices, and biosensors. Multiple investigations have been carried out on polymeric materials for cargo delivery purpose to understand how they behave over time. Block copolymer micelles (BCMs) have demonstrated superiority to deliver cargo, especially in drug delivery due to their encapsulation of hydrophobic agents. This dissertation will mainly study BCMs for potential applications in cargo delivery.
Methods to study BCMs, including NMR spectroscopy, relaxometry and diffusometry, can provide valuable molecular information, such as chemical structure, translational motion, inter- or intramolecular interaction, dynamics, and exchange kinetics. Therefore, this dissertation describes applications of versatile NMR methods to reveal the fundamental behaviors of block copolymer self-assemblies, such as their dynamic stability, cargo partitioning, polymer chain exchange, and chain distribution in solution.
We have investigated two BCM systems. Poly(ethylene oxide)-b-(ε-caprolactone) (PEO-PCL) is a model system to study BCM dynamic stability. PEO-PCL can self-assemble into spherical micelles at 1% w/v in D2O-THF-d8 mixed solvents. We used NMR diffusometry to quantify diffusion coefficients and populations of micelles and unimers (i.e. free polymer chains in solution) over a range of temperature (21 – 50 °C) and solvent composition (10 – 100 vol % THF-d8). By mapping the micelle-unimer coexistence phase diagrams, we are able to enhance our ability to understand and design micelle structure and dynamics. Moreover, we can also probe the chain exchange kinetics between micelles using a new technique we developed – time-resolved NMR spin-lattice relaxation (T1) or TR-NMR. This technique is an analog to time-resolved small-angle neutron scattering (TR-SANS), which can monitor specific signal intensity changes caused after mixing of isotope-labeled micelle solutions.
A second system, Pluronic® F127 (PEO99PPO69PEO99) is a test system to study BCM structure and dynamic changes upon drug uptake. Pluronic® F127 is a commercial copolymer that can solubilize different hydrophobic drugs in micelles. We successfully encapsulated three model drugs into Pluronic® F127 BCMs and investigated the effects of polymer concentration and drug composition on drug partitioning fractions. Also, we proposed to design and synthesize a series of block copolymers with varied glass transition temperatures in core-forming blocks. Using NMR diffusometry, we have measured the existing unimer concentrations in micellar solutions and correlated these results with chain mobility and internal chemical composition.
Lastly, we have extended our expertise in NMR and polymers into the study of ion-containing polymer systems (polyelectrolytes). A critical problem in polymer science is the inability to reliably measure the molecular weight of polyelectrolytes. We are developing methods to solve this problem by using NMR diffusometry, rheology, scattering, and scaling theories to accomplish general molecular weight measurements for polyelectrolytes.
In short, this dissertation describes studies to provide more perspectives on structural and dynamic properties at various time and length scales for polymeric materials. NMR measurements, in combination with many other advanced techniques, have given us a better picture of soft matter behaviors and provided guidance for synthesis and processing efforts, especially in block copolymer micelles for delivery purposes.Doctor of Philosophy
Block copolymers have been extensively applied in diverse fields in packaging, electrolytes and nano-scale drug delivery carriers. In the area of cancer treatment, only a limited number of drug nanocarriers have been approved for clinical applications. Therefore, it is very important to understand the principles behind drug delivery for targeted purposes. There have been many studies on polymeric delivery carriers but their behaviors have not been completely understood. Therefore, we have tremendous interest in unraveling the mysteries in those polymeric systems. Among a multitude of techniques to study block copolymer materials, the NMR method serves as a potent tool for its non-destructive, chemical-specific and isotope-selective merits. NMR can provide basic information about block copolymer self-assembly and other polymeric properties, such as chemical structure, molecular interactions and diffusion coefficients of species of interests. Chapters 3, 4, 5, 6, and 7 have investigated different classes of polymeric materials, mainly block copolymer micelles, for their structure and stability, exchange kinetics of polymer chains or cargo, and translational properties. Greater understanding about the fundamental properties of these polymeric systems, is essential for enabling new applications and new research areas.
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Dinc, Havva. "Genotyping Of Beta-casein, Kappa-casein And Beta-lactoglobulin Genes In Turkish Native Cattle Breeds And Efforts To Delineate Bcm-7 On Human Pbmc". Phd thesis, METU, 2009. http://etd.lib.metu.edu.tr/upload/3/12611173/index.pdf.
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The main aim of this study is to determine genetic diversity of milk protein genes associated with milk traits, namely beta-casein, kappa-casein and betalactoglobulin, in native Turkish cattle breeds (Turkish Grey, Eastern Anatolian Red, Anatolian Black, and Southern Anatolian Red) and Turkish Holstein. Only
11% deviation from the Hardy-Weinberg equilibrium and insignificant Fis values for the populations were observed, indicating that samples are free of inbreeding.
B alleles of these genes, which are positively related with cheese yield and quality, seem to be relatively high in native Turkish breeds. Therefore, the results suggest that milk of Turkish native breeds is advantageous for producing high-quality and -yield cheese.
A1 allele of beta-casein, which releases a bioactive peptide called BCM-7 after successive gastrointestinal proteolytic digestions, has been claimed to have adverse health effects on humans. Another aim of this study is to develop a protocol and assess the potential detrimental effects of BCM-7 on human peripheral blood cells. Despite the fact that the results are inconclusive, the optimized experimental protocol will guide further researchers while judging the effect of BCM-7 on human health.
Even though A1 beta-casein, which has a low frequency in native Turkish breeds, and hence BCM-7 have no adverse health effects on humans, this probability should be enough to keep its frequency low in native cattle breeds. Bulls must be screened for A1 allele of beta-casein as well as E allele of kappa-casein, which is absent in native breeds and known to have detrimental effects on cheese quality.
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Frisancho, Robles Julio César. "Uso de marcadores COSII en la elaboración y comparación de mapas de ligamiento del cromosoma 3 en poblaciones diploides de papa BCT y B3C1HP". Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2016. https://hdl.handle.net/20.500.12672/5639.
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Publicación a texto completo no autorizada por el autorEvalúa la utilidad de los marcadores COSII para el mapeo de genes en el cromosoma 3, comparando el nivel de polimorfismos entre dos poblaciones diploides de papa B3C1HP y BCT, que han sido previamente analizadas en estudios de resistencia a Phytophthora infestan. El polimorfismo de estos marcadores COSII es evaluado por 3 diferentes métodos: agarosa, Polimorfismos Conformacionales de Secuencia Simple (SSCP) y Melting de Alta Resolución (HRM).
Tesis
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Bijalwan, Vijay. "Studie syntéz a přípravy bezolovnaté keramiky (Ba,Ca)(Ti,Zr)O3 v závislosti na struktuře a výsledných vlastností". Doctoral thesis, Vysoké učení technické v Brně. CEITEC VUT, 2018. http://www.nusl.cz/ntk/nusl-390293.
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V poslední době je snahou nahradit klasickou komerční olovnatou piezoelektrickou keramiku bezolovnatou, z důvodu zvýšeného zájmu o ochranu životního prostředí a zdraví. Různé typy materiálů již byly navrženy, jako například (K, Na) NbO3 (KNN), (Bi, Na) TiO3 (BNT), (Bi, Na) TiO3 – BaTiO3 (BNT-BT), ale jejich piezoelektrické vlastnosti zatím nedosáhly takových hodnot jako u olovnatý chkeramik (např. olovnatý titanát olova ((Pb Zr)TiO3). Nejvíce se olovnatým materiálů blíží bezolovnatý systém na bázi (1-x)Ba(Zr0.2Ti0.8)O3-x(Ba0.7Ca0.3)TiO3 nebo (Ba, Ca) (Zr, Ti) O3 ((1-x)BZT-xBCT, BCZT) a to díky vysokým piezoelektrickým a dielektrickým parametrům. Nevýhodou tohoto prostředku je jeho velmi vysoká teplota slinování (1520 ° C) za účelem dosažení vysokých piezoelektrických vlastností (např. Piezoelektrické konstanty d33 > 600 pC / N). Tato práce se zabývá bezolovnatou keramikou na bázi BCZT, její výrobou a vylepšením piezoelektrických vlastností dopováním CeO2. Přidáním CeO2 (y wt.%) do (Ba0.85Ca0.15) (Zr0.1Ti0.9) O3 se výrazně snížila slinovací teplota a došlo ke zhutnění při 1350°C. U této kompozice se Curieova teplota pohybovala kolem TC~105°C a velikost zrn byla v rozmezí ~ 10-13 m. Fázový přechod z romboedrické struktury na tetragonální (R-T) byl zjištěn pomocí rentgenové spektroskopie u y = 0 - 0.1 wt.%, což koreluje s výsledky Ramanovy spektrální analýzy. Mikrostrukturní a strukturní charakteristiky byly detailně studovány v korelaci s dielektrickými, feroelektrickými a piezoelektrickými vlastnostmi. Nejlepší funkční vlastnosti byly dosaženy pro keramiku BCZT – 0.07 wt.% CeO2. Tato keramika vykazovala piezoelektrický nábojový koeficient d33 = 507±20pC/N, elektromechanický planární koeficient kp = 51.8 %, dielektrickou konstantu r = 4091±100, ztrátový činitel tan = 0.02, remanentní polarizaci Pr = 13.58C/cm2, intenzitu koercitivního pole EC = 2.13kV/cm při normovaném napětí, d33* nebo Smax/Emax = 840pm/V. Dvoustupňovou kalcinační technikou bylo docíleno homogenního růstu zrn s vysokou relativní hustotou (~ 99% teoretické hustoty). Tato kompozice BCZT- CeO2 vykazovala stálé feroelektrické, dielektrické a piezoelektrické vlastností i při velikosti zrn 10 µm. Bezolovnatá piezoelektrická keramika (Ba0.85Ca0.15-y Cey) (Zr0.1Ti0.9) O3 (BCCeZT) byla dále dopována CeO2 s cílem substituce Ce4+ v místě A krystalické mřížky. Posunutí rentgenových vrcholů k vyšším úhlům naznačuje kontrakce mřížky, což by mohlo způsobit obsazení iontů ceru v místech A této soustavy. Bylo zjištěno, že velikost zrn kolem 10 - 12 m je významná pro vysokou piezoaktivitu bezolovnaté BCCeZT keramiky. Nejvyšší piezoelektrické vlastnosti tato keramika vykazovala při y;Ce = 0.00135 a slinovaná na teplotě 1350°C/4h, kdy piezoelektrické parametry byly d33 = 501±10 pC/N, kp = 38.5±1.92 %, Pr = 12.19 C/cm2, TC = 108.1 °C a s maximální deformací S do 0.14 %. Pro další studium substituce v místě A, byly vyrobeny keramické materiály (Ba1-x-y Cax Cey) (Zr0.1 Ti0.9) O3 (x:Ca = 0.05, 0.10, 0.15, 0.20 a y;Ce = 0.00135). Opět se ukázalo, že pokud byla velikost zrn ~13um, tak keramika vykazovala vysoké piezoelektrické vlastnosti (d33 = 457pC/N) pro x = 0.15 % kalcinované na teplotě 1425 °C. Když se se velikost zrn zvýšila nad 16 um, piezoelektrický nábojový koeficient d33 klesl na 200 pC/N. Rentgenová analýza ukázala změnu fázové struktury z rombické na tetragonální při zvýšení obsahu vápníku.
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Starke, Ansunette. "The implications of ideology for society and education in South Africa". University of the Western Cape, 1996. http://hdl.handle.net/11394/8472.
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Magister Educationis - MEdIdeology reveals itself in the commonly shared ideas and ideals which act as the driving force responsible for group formation underlying nationalist aspirations in society. It reveals itself in various ways with politics as the most visible and education as the most powerful, yet unobtrusive, manifestation. In South Africa Afrikaner Nationalism and Black Nationalism have been involved in a titanic battle for the last fifty years. The ideology of Afrikaner Nationalism developed as a striving for political, cultural and educational freedom from British imperialist domination. An important part of this struggle was waged in the field of education, leading to the development of the sub-ideology of Christian National Education. The tenacity with which the Afrikaner pursued his nationalist aspirations was rewarded with the recognition of Afrikaans as official language in 1925, the National Party gaining political power in 1948 and the establishment of the Afrikaner educational ideology, Christian National Education, as state education policy in 1967. The Afrikaner Broederbond, under the cover of an Afrikaner cultural society, exercised a tremendously strong influence in the political, economic and social spheres. With the support of the extremely influential Dutch Reformed Church hegemonic rule was further consolidated. In order to attain its ideals and maintain its position of power, Afrikanerdom engaged in suppressing the Black sector of the population. This manifested in the denial of political and human rights to Blacks, and was reinforced by an education system which offered Blacks inferior education to that of Whites to ensure that they would not become a threat to Afrikaner power. The Afrikaner Broederbond, under the cover of an Afrikaner cultural society, exercised a tremendously strong influence in the political, economic and social spheres. With the support of the extremely influential Dutch Reformed Church hegemonic rule was further consolidated. In order to attain its ideals and maintain its position of power, Afrikanerdom engaged in suppressing the Black sector of the population. This manifested in the denial of political and human rights to Blacks, and was reinforced by an education system which offered Blacks inferior education to that of Whites to ensure that they would not become a threat to Afrikaner power tendency towards communalism in Black society resulted in Black Nationalism adopting the ideology of Black Liberation Socialism, under whose banner many former colonies had attained independence from their European mother countries. The educational sub ideology of People's Education served the Black Nationalist ideal by adopting in its curricula, syllabi and organisational structure an approach which supported Black liberation from the apartheid regime. The South African state (government, the police, the legal system, etc.) acted in a repressive manner under the influence of the Afrikaner ideology. The oppression Afrikaners suffered at the hand of British imperialism was repeated when Afrikaner Nationalism assumed power under the Nationalist government. It subjected Blacks to oppression and totally negated Black nationalist aspirations. Education always serves the dominant ideology - a concept clearly manifested in Christian National Education as it served the Afrikaner Nationalist ideology. In the same manner People's Education proved to be an extension of the Black Liberation Struggle. Ideology is thus in the service of power. Ample evidence exists that Afrikaner Nationalism and Christian National Education served to entrench Afrikanerdom in a position of seemingly unassailable power for an extended period of time after it had discarded the British imperialist yoke. This dominant position was maintained despite being a minority group. Should the same pattern prevail one would expect the African National Congress to abuse its present position of power to oppress the White minority and take revenge for the suffering that the latter had inflicted on Blacks for so many years. Both the Oppressed and the Oppressor are dehumanised in the process of oppression. Although the Afrikaner was in a dominant, powerful position and seemingly free, he became enslaved to his own ideology. He was deprived of independent opinion and thought by the prescriptive ideology of Afrikaner Nationalism and its educational ideology of Christian National Education. Non-compliance was frowned upon and deviants ostracised. It is ironic that, by ousting the Afrikaner nationalist regime, the African National Congress actually became the agent which liberated the Afrikaner from his self inflicted ideological oppression. Oppression thus seems to follow a vicious circle with both the Oppressor and the Oppressed suffering dehumanisation. Unless the Oppressed is rehumanised the oppressive role model presented by the Oppressor is emulated and the former Oppressed become the new Oppressor. The necessity for the process of rehumanisation to occur in the postapartheid South African society can not be over-emphasised and thus various steps that can be taken to effect rehumanisation are suggested.
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Nedvěd, Jiří. "Zpracování genomických signálů fraktály". Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2012. http://www.nusl.cz/ntk/nusl-219634.
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This diploma project is showen possibilities in classification of genomic sequences with CGR and FCGR methods in pictures. From this picture is computed classificator with BCM. Next here is written about the programme and its opportunities for classification. In the end is compared many of sequences computed in different options of programme.
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De, Paoli Davide. "Reti neurali artificiali e apprendimenti basati sulla biofisica dei neuroni". Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amslaurea.unibo.it/22983/.
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Frank Rosenblatt, padre del percettrone, nel 1962 sottolineò che l’ obiettivo ultimo della ricerca nel campo delle reti neurali artificiali doveva essere “indagare le strutture fisiche ed i principi neurodinamici che stanno alla base dell’intelligenza naturale”. A differenza di quel che desiderava Rosenblatt, i metodi maggiormente utilizzati e di conseguenza studiati sono quelli supervisionati, non biologicamente plausibili, ritenuti maggiormente efficaci rispetto alle reti che sfruttano metodi di apprendimento ispirati dalla biofisica dei neuroni. L’ obiettivo della tesi è quello di analizzare due metodi di apprendimento non supervisionati basati su sistemi neuronali biologici: il modello di L.Bienenstock, N.Cooper e W. Mundro del 1982 (BCM) ed il modello di D.Krotov e J.Hopfield del 2019, e comprenderne le reali capacità. La prima parte della tesi rappresenta un’ introduzione al concetto di rete neurale artificiale, al significato di rete multistrato e all’ algoritmo di apprendimento della retro propagazione dell’ errore, tipico delle reti supervisionate. La seconda parte della tesi illustra il funzionamento della BCM e della rete di Hopfield e Krotov. Nei risultati riguardanti la rete del 2019, viene riportato un confronto tra questo modello ed un modello addestrato tramite retro propagazione dell’ errore, con cui riesce a competere nel riconoscimento delle immagini appartenenti a due data set: il MNIST ed il CIFAR-10. Per quanto riguarda la BCM, vengono riportati e discussi i risultati di alcune simulazioni effettuate con la rete modello BCM della libreria Plasticity. Lo scopo delle simulazioni era quello di portare i pesi della rete a memorizzare il maggior numero di pattern differenti possibili, appartenenti al data set MNIST.
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Farias, Carlene Paula Silva de. "Competing orders in Uru2Si2: from ordered magnetism to spin liquid phases". PROGRAMA DE P?S-GRADUA??O EM F?SICA, 2017. https://repositorio.ufrn.br/jspui/handle/123456789/23653.
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The main objective of this thesis is to investigate the competing ordered phases in the metallic heavy fermion compound URu2Si2, which displays a bodycentered tetragonal lattice. We first provide a study case of the competition between antiferromagnetic (AF) and spin liquid phases. The antiferromagnetic state is study with spin-wave theory. Whereas the spin liquid analysis has been carried out in an algebraic spin liquid representation. In the second part, we describe an effective theory for Raman scattering experiments at these particular phases. We provide insight about the hidden order phase displayed by the heavy fermion compound URu2Si2.
L?objectif central de cette th?se est d??tudier des phases ordonn?es en comp?tition dans des mat?riaux magn?tiques pr?sentant une structure cristalline t?tragonale centr?e. Ce travail est divis? en deux parties principales. Dans la premi?re, nous pr?sentons les r?sultats de notre ?tude de la comp?tition entre des ?tats ordonn?s antiferromagn?tiques et des phases liquides de spin. Nous montrons comment ces derni?res peuvent ?tre stabilis?es par la frustration g?om?trique et par une g?n?ralisation de la sym?trie de spin au groupe SU(n). Les ?tats antiferromagn?tiques sont d?crits par une th?orie d?onde de spin et l?analyse de liquide de spin est effectu?e par une repr?sentation fermionique des op?rateurs de spin. Dans la deuxi?me partie, nous d?crivons une th?orie effective pour d?rcrire des exp?riences de diffusion Raman. Nous fournissons un aper?u de la phase d?ordre cach? affich?e par le compos? de fermions lourds URu2Si2.