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Artykuły w czasopismach na temat "Antidepressant medication"

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Adhikari, Kamala, Scott B. Patten, Sangmin Lee i Amy Metcalfe. "Adherence to and Persistence with Antidepressant Medication during Pregnancy: Does It Differ by the Class of Antidepressant Medication Prescribed?" Canadian Journal of Psychiatry 64, nr 3 (25.09.2018): 199–208. http://dx.doi.org/10.1177/0706743718802809.

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Objective: Pregnant women are often concerned about the impact of medication use on their pregnancy, such as congenital abnormalities. This study examined the rate of adherence to and persistence with antidepressant medications during pregnancy based on the class of antidepressants prescribed. Methods: Women who gave birth between 2012 and 2015 in Alberta, Canada; had ≥1 diagnosis of depression within 1 year of preconception in outpatient physician claims, emergency department, or hospitalization administrative data; and were adherent (medication possession ratio ≥80%) to ≥2 consecutive antidepressant prescriptions during the preconception year ( n = 1865) were included in this retrospective cohort study. The rates of adherence and persistence (prescription refill gap ≤30 days) were calculated by antidepressant class and were compared using chi-square tests. Results: During pregnancy, 834 (44.7%; 95% CI, 42.4% to 47.0%) women discontinued antidepressants. Among those continuing antidepressants, the overall rate of adherence was 62.6% (95% CI, 59.4% to 65.7%). The rate differed significantly by medication class ( P < 0.0001), with a rate of 75.1% (95% CI, 68.3% to 80.9%) for serotonin-norepinephrine inhibitors, 60.9% (95% CI, 57.2% to 64.5%) for selective serotonin reuptake inhibitors, 42.8% (95% CI, 19.9% to 69.3%) for nonselective monoamine reuptake inhibitors, and 37.5% (95% CI, 22.5% to 55.4%) for atypical antidepressants. Only, 40.7% (95% CI, 37.5 to 44.1) of women were persistent with antidepressants for the full pregnancy period—the rate differed significantly by medication class ( P < 0.0001). Conclusions: Adherence to and persistence with antidepressants is low during pregnancy and varies by medication class. Low adherence and persistence can interfere with a therapeutic effect of antidepressants, which may contribute to the worsening of depression symptoms.
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Antimisiaris, Demetra, Brittany McHolan, Daniela Moga i Cortney Mospan. "Medication Related Problems". Senior Care Pharmacist 36, nr 2 (1.02.2021): 68–82. http://dx.doi.org/10.4140/tcp.n.2021.68.

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When selecting and managing psychoactive medications in older people, it is equally important to focus on avoidance of toxicity as it is to focus on efficacy. Higher psychoactive medication load is associated with increased rate and risk of all cause hospitalization. The medication classes used to treat depression and related comorbidities include antidepressants, antipsychotics, stimulants, mood stabilizers, lithium, anxiolytics and sedative hypnotics. This discussion will examine considerations to help avoid medication related problems relevant to medications used to treat depression in the antidepressant pharmacological class.
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Antimisiaris, Demetra, Brittany McHolan, Daniela Moga i Cortney Mospan. "Medication Related Problems". Senior Care Pharmacist 36, nr 2 (1.02.2021): 68–82. http://dx.doi.org/10.4140/tcp.n.2021.68.

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When selecting and managing psychoactive medications in older people, it is equally important to focus on avoidance of toxicity as it is to focus on efficacy. Higher psychoactive medication load is associated with increased rate and risk of all cause hospitalization. The medication classes used to treat depression and related comorbidities include antidepressants, antipsychotics, stimulants, mood stabilizers, lithium, anxiolytics and sedative hypnotics. This discussion will examine considerations to help avoid medication related problems relevant to medications used to treat depression in the antidepressant pharmacological class.
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Istilli, Plínio Tadeu, Adriana Inocenti Miasso, Cláudia Maria Padovan, José Alexandre Crippa i Carlos Renato Tirapelli. "Antidepressants: knowledge and use among nursing students". Revista Latino-Americana de Enfermagem 18, nr 3 (czerwiec 2010): 421–28. http://dx.doi.org/10.1590/s0104-11692010000300018.

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This study examined the knowledge of nursing students in regard to using antidepressant medication and proposes actions such that nurses contribute to a safe and effective antidepressant therapy. This cross-sectional and descriptive study was conducted in a public nursing school in the state of São Paulo, Brazil, between March and November 2008. Fifty-two (19%) out of the 273 participants were using or had used antidepressants. Instruction concerning the use of antidepressants was provided by physicians. Even after receiving instruction concerning the antidepressant treatment before its administration, the majority of users (cII1=0.07, p> 0.05) still had doubts about its use. Fluoxetine was the most prevalent antidepressant. Actions to improve knowledge concerning the use of antidepressant medications, their side and therapeutic effects, seem to be necessary and relevant.
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Adams, Nicholas Norman. "Do Newer Antidepressant Drugs Really Have Reduced Side Effects? Examining a Random “Real World” Sample of 300+ Receivers of Medications". IAFOR Journal of Psychology & the Behavioral Sciences 6, nr 1 (12.12.2020): 75–100. http://dx.doi.org/10.22492/ijpbs.6.1.05.

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Newer antidepressant drugs are frequently cited as having reduced side effect profiles to that of their older counterparts. However, recent studies have begun to dispute this claim, citing selective sampling, short clinical trials, and clinical trial environments as influencing reported outcomes. At present, little research on antidepressant side effects draws on RWD (Real-World Data). Despite this, interest in examining RWD samples for antidepressant drug side effects is increasing as of 2020. The reported study asked a random sample of 300+ individuals taking a variety of different antidepressant medications to complete online drug side effect self-report scales with previously high validity. Newer antidepressants belonging to the atypical antidepressant drug class were reported as having only slightly reduced side effects of weight gain compared with older SSRI-class medications. No reduced side effects of increased depression, anxiety, sexual dysfunction (SD), sleepiness, or suicidal ideation (SI) were found for the newer atypical-class medications vs older SSRI-class agents. Medication adherence did not differ significantly between SSRI and atypical classes. No evidence for reduced side effects was found for newer SSRI and atypical antidepressants vs older same-class drugs when comparing six new and old medications drawn from atypical and SSRI classes. However, atypical antidepressants were associated with increased use of adjunct medications to bolster primary treatment.
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Thommasen, Harvey V., Earle Baggaley, Carol Thommasen i William Zhang. "Prevalence of Depression and Prescriptions for Antidepressants, Bella Coola Valley, 2001". Canadian Journal of Psychiatry 50, nr 6 (maj 2005): 346–52. http://dx.doi.org/10.1177/070674370505000610.

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Objective: To determine the prevalence of depression–anxiety disorders and the degree to which physicians prescribed antidepressants for Aboriginal and non-Aboriginal populations living in a remote rural community in British Columbia in 2001. Methods: To obtain data for our main outcome measures, we retrospectively reviewed the charts of 2375 patients living in the Bella Coola Valley as of September 2001 and attending the Bella Coola Medical Clinic. Results: The 2001 prevalence rate of depression–anxiety disorders in the Bella Coola Valley was 7.5% (177/2375). Depression was the most common problem (86%) in these patients. Women had a higher rate of depression–anxiety disorders (10.3%) than did men (4.7%) ( P < 0.001). Non-Aboriginal people had a slightly higher rate (8.5%) than did Aboriginal people (6.3%); however, the difference was not statistically significant. Antidepressant medications were commonly prescribed for chronic pain and insomnia. The general pattern of antidepressant medication use in 2001 among both Aboriginal and non-Aboriginal people living in the Bella Coola Valley was as follows: peak use of antidepressants was in the middle to late years; the rate for women was roughly double the rate for men; and proportionately more Aboriginal people, especially the women, were taking antidepressants. Conclusions: Depression–anxiety disorder prevalence rates for Aboriginal and non-Aboriginal populations are similar. When using antidepressant medication prescriptions as a community health indicator, health care administrators should be aware that antidepressant medications are commonly prescribed for conditions other than depression–anxiety disorder.
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Viktorin, A., R. Uher, A. Reichenberg, S. Z. Levine i S. Sandin. "Autism risk following antidepressant medication during pregnancy". Psychological Medicine 47, nr 16 (22.05.2017): 2787–96. http://dx.doi.org/10.1017/s0033291717001301.

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BackgroundPrevious studies have examined if maternal antidepressant medication during pregnancy increase the risk of autism spectrum disorder (ASD) in the offspring, but the results have been conflicting.MethodsIn a population-based cohort of 179 007 children born in 2006 and 2007 and followed through 2014 when aged 7 and 8, we estimated relative risks (RRs) of ASD and 95% confidence intervals (CIs) from Cox regression in children exposed to any antidepressant medication during pregnancy, and nine specific antidepressant drugs. Analyses were adjusted for potential confounders and were conducted in the full population sample, and in a clinically relevant sub-sample of mothers with at least one diagnosis of depression or anxiety during life.ResultsThe adjusted RR of ASD in children of mothers who used antidepressant medication during pregnancy was estimated at 1.23 (95% CI 0.96–1.57), and at 1.07 (95% CI 0.80–1.43) in women with a history of depression or anxiety. Analyses of specific antidepressants initially revealed increased RRs of offspring ASD confined to citalopram and escitalopram (RR: 1.47; 95% CI 0.92–2.35) and clomipramine (RR: 2.86; 95% CI 1.04–7.82).ConclusionMedication with antidepressants during pregnancy does not appear to be causally associated with an increased risk of ASD in the offspring. Instead, the results suggest that the association is explained by factors related to the underlying susceptibility to psychiatric disorders. Based on these findings, the risk of ASD in the offspring should not be a consideration to withhold treatment with commonly used antidepressant drugs from pregnant women.
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Meyers, Barnett S. "Late-Life Delusional Depression: Acute and Long-Term Treatment". International Psychogeriatrics 7, S1 (październik 1995): 113–24. http://dx.doi.org/10.1017/s1041610295002390.

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Treatment studies of delusional major depression demonstrate a poor response to standard antidepressant medications. Longitudinal studies demonstrate high relapse rates, even in patients receiving postdischarge antidepressants. The poor medical and psychiatric outcomes for late-life delusional depression and the increased risk for adverse medication reactions in this population underscore the importance of developing effective postrecovery treatments.Studies of mixed-age adults demonstrate the effectiveness of acute treatment with either electroconvulsive therapy or combination pharmacotherapy with high doses of neuroleptics and antidepressants. In considering these results in relation to the treatment of late-life delusional depression, attention must be given to the particular vulnerabilities to medication side effects of elderly patients.The potential effectiveness of continuation treatment with combined antidepressant-neuroleptic therapy is discussed. Clinical and methodologic issues related to studying the effectiveness of combination treatment in elderly patients are emphasized.
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Bjørklund, Louise, Henriette Thisted Horsdal, Ole Mors, Søren Dinesen Østergaard i Christiane Gasse. "Trends in the psychopharmacological treatment of bipolar disorder: a nationwide register-based study". Acta Neuropsychiatrica 28, nr 2 (11.09.2015): 75–84. http://dx.doi.org/10.1017/neu.2015.52.

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ObjectiveIn bipolar disorder, treatment with antidepressants without concomitant use of mood stabilisers (antidepressant monotherapy) is associated with development of mania and rapid cycling and is therefore not recommended. The present study aimed to investigate the psychopharmacological treatment patterns in bipolar disorder over time, with a focus on antidepressant monotherapy.MethodsCohort study with annual cross-sectional assessment of the use of psychotropic medications between 1995 and 2012 for all Danish residents aged 10 years or older with a diagnosis of bipolar disorder registered in the Danish Psychiatric Central Research Register. Users of a given psychotropic medication were defined as individuals having filled at least one prescription for that particular medication in the year of interest.ResultsWe identified 20 618 individuals with bipolar disorder. The proportion of patients with bipolar disorder using antidepressants, atypical antipsychotics and anticonvulsants increased over the study period, while the proportion of patients using lithium, typical antipsychotics and benzodiazepines/sedatives decreased. The proportion of patients treated with antidepressant monotherapy decreased from 20.5% in 1997 to 12.1% in 2012, and among antidepressant users, the proportion in monotherapy decreased from 47.7% to 23.9%, primarily driven by a decrease in the use of tricyclic antidepressants.ConclusionThe results show an increase in the proportion of patients with bipolar disorder being treated with antidepressants in the period from 1997 to 2012. However, in accordance with international treatment guidelines, the extent of antidepressant monotherapy decreased during the same period.
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Galbally, Megan, Andrew J. Lewis, Jarrad Lum i Anne Buist. "Serotonin Discontinuation Syndrome Following in Utero Exposure to Antidepressant Medication: Prospective Controlled Study". Australian & New Zealand Journal of Psychiatry 43, nr 9 (1.01.2009): 846–54. http://dx.doi.org/10.1080/00048670903107583.

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Objectives: The aim of the present study was to examine neonatal symptoms previously reported to be associated with exposure to antidepressant medication in late pregnancy in a group of infants exposed to antidepressants, using a prospective and controlled design. Method: A prospective case–control study recruited 27 pregnant women taking antidepressant medication and 27 matched controls who were not taking antidepressant medication in pregnancy. Of the 27 women taking medication, 25 remained on medication in the third trimester and, of these, 23 women had complete data available. In pregnancy and after delivery women were assessed with the Beck Depression Inventory-II and a purpose-designed questionnaire. After delivery mothers were asked a set of nine questions pertaining to symptoms of discontinuation in their newborn and questions about pregnancy and delivery complications. Results: There was an increased risk of discontinuation symptoms in neonates exposed to antidepressant medication in late pregnancy and an association with higher dose medication. The study group were found to be significantly more likely to display behaviour such as crying, jitteriness, tremor, feeding, reflux and sneezing and sleep for <3 h after a feed. They also had significantly higher rates of jaundice and admissions to the special care nursery. Conclusions: Exposure to antidepressants in late pregnancy is associated with a range of symptoms in the neonate that are consistent with the effects of exposure to antidepressants in late pregnancy. The clusters of symptoms most highly correlated are the gastrointestinal and central nervous system symptoms. These finding helps to identify the common symptoms associated with a neonatal serotonin discontinuation syndrome.
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Rozprawy doktorskie na temat "Antidepressant medication"

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Åkerblad, Ann-Charlotte. "Adherence to Antidepressant Medication". Doctoral thesis, Uppsala University, Department of Neuroscience, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7769.

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Non-adherence to medication is a major obstacle in the treatment of depression. The objectives of the present study were to explore the effect of two interventions aiming to increase antidepressant treatment adherence, and to examine long-term consequences and costs of depression in adherent and non-adherent primary care patients.

A randomised controlled design was used to assess the respective effects of a written educational adherence enhancing programme and therapeutic drug monitoring in patients with major depression treated with sertraline for 24 weeks. All patients were prospectively followed during two years.

Treatment adherence was found in 41% of the 1031 included patients. None of the interventions resulted in a significant increase in adherence rate. However, significantly more patients in the group receiving the written educational material had responded at week 24 as compared to patients in the control group.

The overall remission rate after two years was 68%. In total, 34% of the responders experienced at least one relapse. Response and remission rates at week 24, year 1 and year 2 were significantly higher in adherent as compared to non-adherent patients. No relationship between adherence and relapse rate was seen.

The mean total cost per patient during two years was KSEK 363 whereof indirect costs represented 87%. No significant differences in costs between intervention groups or between adherent and non-adherent patients could be demonstrated. However, the mean cost per patient was 39% lower for treatment responders as compared to non-responders.

Non-adherence was predicted by age below 35 or above 64 years, no concomitant medications, personality disorder, sensation seeking personality traits and substance abuse.

The results indicate a strong positive relationship between treatment adherence and clinical outcome. In addition, the study shows that depression is a costly disease and that certain patient characteristics predict non-adherence.

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Åkerblad, Ann-Charlotte. "Adherence to antidepressant medication /". Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7769.

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Cotterchio, Michelle. "Antidepressant medication use and breast cancer risk". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0007/NQ41131.pdf.

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Gallagher, Shawn Patrick, i Shawn Patrick Gallagher. "Antidepressant Medication Adherence in Active Duty Army Soldiers". Diss., The University of Arizona, 2017. http://hdl.handle.net/10150/626157.

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Depression can be painful, disabling, and result in fatal consequences. The most common treatment, antidepressant medication, can effectively treat depressive symptoms. Though, adhering to antidepressant medication treatment is a complex phenomenon that can elude even the most informed who suffers from depression. While much is known about antidepressant medication adherence in the general population, there is a dearth of knowledge about it in active duty United States Army soldiers with depression. The purpose of this research was to explore antidepressant adherence among United States Army soldiers with depression in relation to the potential correlates of illness perceptions, beliefs about medication, social support, and selected demographic variables. This descriptive study analyzed findings to determine significant correlations or predictors of antidepressant adherence in soldiers with depression. Fifty-one participants, ranging from 24 to 36 years of age (M= 29 years of age) were recruited through Facebook™ (i.e., social media). After answering basic demographic and ‘insider’ knowledge, screening questions participants completed measures of medication adherence, illness perceptions, social support, depression, anxiety, post-traumatic stress, and alcohol use. Age and gender were the only variables significantly associated with medication adherence (r= -0.317, p= 0.024 and r= -0.331, p= 0.018) respectively and the only predictors of antidepressant medication adherence (R2= 0.206, Adjusted R2: 0.173, F: 6.234, p= 0.004). Antidepressant adherence scores indicated low levels of adherence. The findings of this study suggest those who are younger and are female United States Army soldiers may be more likely to report higher levels of antidepressant adherence.
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Linton, Pamela. "Correlates of Antidepressant Medication Compliance Use Among Depressed Women". DigitalCommons@USU, 2001. https://digitalcommons.usu.edu/etd/2537.

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Medication compliance/noncompliance was examined in context of: severity of symptoms; medical side effects; medication education; perceived stigma; and effects on family/social support system. A null hypothesis was formulated for each correlate, stating that those patients who reported a high level of an independent variable (IV) would not be any more likely to discontinue their medication than patients who reported a low level of an IV. To obtain data, a medical usage questionnaire and a depression, assessment (OQT"-45.2) were used. Statistical significance was not obtained for any of the hypothesized relationships but trends were consistent with the established literature. The implication points to the efficacy of relational therapy as a conjunct to the medical treatment of depression.
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Saad, Mysa. "Characteristics of Cardiorespiratory Function During Sleep Related to Depression and Antidepressant Medication Use". Thesis, Université d'Ottawa / University of Ottawa, 2019. http://hdl.handle.net/10393/39417.

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Through a series of original research articles, this thesis explores the characteristics of autonomic cardiac regulation and respiratory function during sleep in association with depression and antidepressant medication use and validates a novel diagnostic biomarker of depression. Cardiorespiratory dysfunction during sleep may contribute to the increased risk of developing cardiovascular disease amongst individuals with depression. Sleep represents a unique physiological state shielded from many external confounding factors and may be a more relevant window to observe the effects of depression on cardiorespiratory function. In a first study, we found that depression was associated with abnormal autonomic modulation of cardiac activity during sleep. Specifically, depression was associated with reduced heart rate variability compared to healthy controls, and this difference was most prominent during sleep as compared to wake, which may indicate impairments in the parasympathetic modulation of the cardiac sinoatrial node. Secondly, we validated a machine-learning algorithm that uses patterns of heart rate during sleep to identify depression. This algorithm was found to have 79.9% classification accuracy, based on the differences in autonomic modulation associated with distinct mental states. The algorithm was highly generalizable across different depression subgroups and thus may be useful as an adjunct diagnostic tool. Finally, we found that the use of antidepressants, particularly serotonergic agents, was associated with worse sleep-related respiratory disturbances compared to non-medicated individuals with depression and those using non-serotonergic antidepressants. We proposed that depression-related alterations in serotonin receptor expression and binding may shape the response of the respiratory system to the use of serotonergic agents. Considering the high comorbidity between depression and sleep-related breathing disturbances and their impact on cardiovascular health, this has great clinical implications for the management of depression. Taken together, these results show that depression is associated with several sleep-related abnormalities in terms of cardiorespiratory function, which may represent a valid biomarker of depression.
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Dimidjian, Sona. "Behavioral activation, cognitive therapy, and antidepressant medication in the acute treatment of major depression /". Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/9064.

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Weaver, Alice. "'Journeys through depression' : patients' experiences of transformational change through mindfulness based cognitive therapy (MBCT) and antidepressant medication (ADM)". Thesis, University of Exeter, 2015. http://hdl.handle.net/10871/18309.

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Background: Mindfulness-based cognitive therapy (MBCT) is a promising new alternative to anti-depressant medication (Kuyken et al., 2015) and whilst some qualitative studies have explored participants' experiences of MBCT, none yet have explored experiences of participants who are considering coming off their antidepressant medication alongside MBCT or how patients experience change in relationships with self, others and illness. Aim: To examine MBCT participants' experience of change across 24 months, particularly in relation to change in views of their self and their illness over time. Method: Thematic analysis of in-depth retrospective interviews with 42 participants, two years after attending an 8 week MBCT group with an invitation to taper their antidepressant medication (ADM). Each participant took part in one retrospective interview which was semi-structured and focused on experiences of MBCT and ADM over the previous two years since attending an MBCT group and how these have impacted on a change in self and experience of illness. Findings and conclusion: Four over-arching themes were found: taking control, relationships (with self, other and illness), rebuilding the self and shifts in perspective. The findings in the current study are very similar to those found in transformation in the physical chronic illness literature (e.g. Paterson et al., 1999). Perhaps MBCT could be the challenge which lead patients suffering from chronic depression towards change and creates a context in which patients can consider self and identity.
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Holland, Kate E., i n/a. "Conformity and resistance: Discursive struggles in the Australian mental health field". University of Canberra. Communication, 2007. http://erl.canberra.edu.au./public/adt-AUC20081022.153830.

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This research explores areas of contention in the mental heath field in Australia through a qualitative analysis of voices and practices that can broadly be seen as talking with and talking back to psychiatry. The thesis is informed by key shifts in thinking that underpin postpsychiatry and analyses a set of materials through an interpretive lens of reading psychiatry against the grain (Bracken & Thomas, 2005; Lewis, 2006). In particular, it examines a failed ethics application to conduct research with people diagnosed with a mental illness, an anti-stigma campaign, the practices of some prominent mental health organisations in Australia, a conversation with two members of an emerging consumer/survivor network in Australia, and a television documentary and online discussion forum about an antidepressant medication. The research draws from discourse analytic methods and concepts from social movement framing research to identify factors shaping conformity and resistance to psychiatric doxa in the Australian mental health field. The research identifies the discursive repertoires that characterise the mental health field as a "game" in which competing perspectives vie for recognition. In relation to research ethics committees, the thesis argues that deference to clinical expertise is a potential barrier to cultural studies of psychiatry and a more inclusive agenda in mental heath research and practice. Some practices for ethics committees to consider when reviewing research that involves people who may have been diagnosed with a mental illness are proposed. The research also identifies problematic features of anti-stigma campaigns that direct their efforts toward protecting and promoting the discourse of biomedical psychiatry. A critique of this type of campaign is offered in relation to perspectives from postpsychiatry and social constructionism. On the basis of this research, it is argued that organisations that champion "mental health literacy" are limited in their ability to give voice to the goals and priorities of those who are calling for a more open, reflexive and democratic debate in mental health. The central argument of this thesis is that elevating first-person and postpsychiatry perspectives is necessary in order to interrogate and address the dominance of the medical model in psychiatry and its consequences.
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Chabenat, Apolline. "Alteration of camouflage and behaviour in two marine invertebrates, Sepia officinalis and Carcinus maenas, by antidepressant medication Hidden in the sand: Alteration of burying behaviour in shore crabs and cuttlefish by antidepressant exposure". Thesis, Normandie, 2020. http://www.theses.fr/2020NORMLH15.

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Les juvéniles de la seiche commune, Sepia officinalis, et du crabe vert, Carcinus maenas, se développent au niveau de la zone intertidale et des eaux côtières affectées par la pollution continentale telle que les résidus pharmaceutiques. Cette recherche se concentre sur les effets de deux antidépresseurs, la fluoxétine et la venlafaxine, sur le camouflage et le comportement de la seiche et du crabe vert. Ces deux molécules sont particulièrement inquiétantes car elles sont conçues pour agir sur le système sérotoninergique et sont communément détectées dans les environnements aquatiques. Ainsi, pour se rapprocher de scénarii d’exposition réalistes, la fluoxétine a été associée ou non à la venlafaxine. Les résultats montrent des effets significatifs à des concentrations environnementalement réalistes, d’autant plus avec le mélange des deux antidépresseurs, sur des paramètres sensibles tels que le comportement d’ensablement, le changement de couleur et la coloration cryptique chez nos deux espèces, ainsi que l’activité locomotrice chez le crabe et le comportement prédateur chez la seiche. En outre, l’exposition de stades de développement précoces aux antidépresseurs semble modifier la maturation et les processus d’apprentissage chez la seiche. Enfin, ces résultats ont démontré la nécessité de mener davantage d’études avec de faibles concentrations sur les comportements clefs d’espèces non-cibles
Juveniles of the common cuttlefish, Sepia officinalis, and the green shore crab, Carcinus maenas, develop themselves in the intertidal zone and coastal waters impacted by continental pollution such as pharmaceutical residues. This research focused on the effects two antidepressants, the fluoxetine and the venlafaxine, on the camouflage and behaviour of cuttlefish and shore crabs. Both molecules are worrying because they are designed to act on serotonergic system and are commonly detected in aquatic environments. Thus, to approach realistic scenario of exposure fluoxetine was either combined or not with venlafaxine. The results show significant effects of antidepressants at environmentally realistic concentrations, especially the combination of fluoxetine and venlafaxine, on sensitive endpoints such as burying behaviour, colour change and background matching, locomotor activity in crabs and predatory behaviour in cuttlefish. Furthermore, the exposure to antidepressants at early development stage seems to alter maturation and/or learning processes in cuttlefish. Overall, these studies demonstrated the need to investigate further with low range concentrations on key behaviours of non-target species
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Książki na temat "Antidepressant medication"

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Deborah, Kotz, red. The antidepressant survival program: How to beat the side effects and enhance the benefits of your medication. New York: Crown Publishers, 2000.

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Hedaya, Robert J. The antidepressant survival guide: The clinically proven program to enhance the benefits and beat the side effects of your medication. New York: Three Rivers Press, 2001.

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Tranquillizers and antidepressants: When to take them, how to stop. London: Sheldon, 2008.

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Painkillers and tranquilisers. Oxford: Heinemann Library, 2004.

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Badger, Frances. Medication management for people with depression in primary care. [Birmingham]: University of Birmingham, 2003.

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United States. Congress. House. Committee on Veterans' Affairs. Exploring the relationship between medication and veteran suicide: Hearing before the Committee on Veterans' Affairs, U.S. House of Representatives, One Hundred Eleventh Congress, second session, February 24, 2010. Washington: U.S. G.P.O., 2010.

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Cotterchio, Michelle. Antidepressant medication use and breast cancer risk. 1999.

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Organization, World Health, red. Dose effects of antidepressant medication in different populations. Amsterdam, The Netherlands: Elsevier, 1986.

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Wegmann, Joseph. Antidepressant Medication Strategies: We've Come a Long Way... or Have We? PESI, 2012.

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Wegmann, Joseph. Antidepressant Medication Strategies: We've Come a Long Way... or Have We? PESI, 2012.

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Części książek na temat "Antidepressant medication"

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Elsenga, S., i R. H. Van den Hoofdakker. "Antidepressant Medication and Total Sleep Deprivation in Depressives". W Neuropsychopharmacology, 639–51. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74034-3_63.

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Rotem-Kohavi, Naama, Sherryl H. Goodman, Ashley Wazana i Tim F. Oberlander. "The Other Side of Prenatal Depression: Developmental Outcomes Associated with Antidepressant Medication Therapy". W Prenatal Stress and Child Development, 565–93. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-60159-1_19.

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Tusken, Megan, Izabella Dutra de Abreu, Audrey Eichenberger, Daniela Vela i Mary “Molly” Camp. "Antidepressant Medication Augmented with Cognitive Behavioral Therapy for Generalized Anxiety Disorder in Older Adults". W Essential Reviews in Geriatric Psychiatry, 83–86. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-94960-0_15.

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Early, Maureen, Logan Wink, Craig Erickson i Christopher J. McDougle. "Antidepressant Medications". W Encyclopedia of Autism Spectrum Disorders, 187–91. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1698-3_815.

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Abrams, David B., J. Rick Turner, Linda C. Baumann, Alyssa Karel, Susan E. Collins, Katie Witkiewitz, Terry Fulmer i in. "Antidepressant Medications". W Encyclopedia of Behavioral Medicine, 101–3. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1005-9_1231.

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Akechi, Tatsuo. "Antidepressant Medications". W Encyclopedia of Behavioral Medicine, 120–21. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-39903-0_1231.

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Early, Maureen, Logan Wink, Craig A. Erickson i Christopher J. McDougle. "Antidepressant Medications". W Encyclopedia of Autism Spectrum Disorders, 239–43. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-91280-6_815.

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Leff, Julian. "A Controlled Trial of Couple Therapy versus Antidepressant Medication for Depressed Patients with a Critical Partner". W New Family Interventions and Associated Research in Psychiatric Disorders, 175–86. Vienna: Springer Vienna, 2002. http://dx.doi.org/10.1007/978-3-7091-6148-7_10.

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Desai, Jignyasa. "Neuropathic Antidepressant Medications". W Pain Management and Palliative Care, 75–83. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2462-2_12.

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Carboni, Lucia, Chiara Piubelli i Enrico Domenici. "Proteome Effects of Antidepressant Medications". W Genomics, Proteomics, and the Nervous System, 399–441. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-7197-5_15.

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Streszczenia konferencji na temat "Antidepressant medication"

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Delgado Rodriguez, J., L. Perez Cordon, M. Bitlloch Obiols, S. Marin Rubio, L. Campins Bernadas, V. Aguilera Jimenez, T. Gurrera Roig i M. Serra Prat. "5PSQ-072 Adequacy of antidepressant medication in elderly patients". W 25th EAHP Congress, 25th–27th March 2020, Gothenburg, Sweden. British Medical Journal Publishing Group, 2020. http://dx.doi.org/10.1136/ejhpharm-2020-eahpconf.389.

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Hooper, Robert, i Tess Compton-Price. "CPAP Therapy improves Depressive Symptoms in OSA Patients, including those using Antidepressant Medication". W ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa4143.

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Silva, André Douglas Marinho da, Ana Caroline Fonseca Silva, Lucas Pablo Almendro i Pedro da Cunha Dantas. "Non-epileptic seizure caused by selective serotonin reuptake inhibitors (SSRI) - case report". W XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.258.

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Context: Seizures are the most frequent clinical emergency neurological manifestation, corresponding to 1-5% of the visits, except for trauma. Several conditions have the potential to reduce the seizure threshold, and the use of antidepressant drugs as selective serotonin reuptake inhibitors is one of those reported. The seizure triggering risk related to SSRIs use is low, being 0.1%, perceptibly lower than that of tricyclic antidepressants, with a 1% rate. Case report: Male patient, previously healthy, 23-year-old, was seen at the Emergency Room in Rio Branco after a generalized seizure lasting 3 minutes. Complementary exams, including computed tomography, were all normal. Magnetic resonance imaging of the skull without atypical findings and electroencephalogram showed dysrhythmia by waves and discrete spicules. Patient reported using escitalopram (esc) 20mg for 3 months after 10mg progression dose, in use for 1 year, without clinical improvement. Due to the seizure event, medication management was switched for sertraline 50mg intake. After 2 months, the patient had a new generalized seizure, preceded by prolonged depersonalization. Complementary exams were normal, 10mg of esc was reestablished and the patient ceased with the seizures. Conclusions: The diagnostic hypothesis: patient’s seizure threshold is low, and seizures are triggered by SSRI higher doses adverse effect. Due to case rarity and SSRI efficacy and tolerance, it is suggested to encourage the discussion about administration safety of these drugs.
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Brieler, Jay, Joanne Salas i Jeffrey Scherrer. "Achievement of glycemic control and antidepressant medication use in comorbid depression and type II diabetes". W NAPCRG 49th Annual Meeting — Abstracts of Completed Research 2021. American Academy of Family Physicians, 2022. http://dx.doi.org/10.1370/afm.20.s1.2902.

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Jayasooriya, N., SK Saxena, J. Blackwell, I. Petersen, A. Bottle, MH Hotopf i RC Pollok. "P114 Changing patterns of antidepressant medication use amongst inflammatory bowel disease patients: a UK population-based study". W Abstracts of the BSG Campus, 21–29 January 2021. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2021. http://dx.doi.org/10.1136/gutjnl-2020-bsgcampus.189.

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Krieg, Anne K., Stefan Hess i Günter Gauglitz. "Optical sensors for therapeutic drug monitoring of antidepressants for a better medication adjustment". W SPIE Optics + Optoelectronics, redaktorzy Francesco Baldini, Jiri Homola i Robert A. Lieberman. SPIE, 2013. http://dx.doi.org/10.1117/12.2017417.

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Raporty organizacyjne na temat "Antidepressant medication"

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Schnabel, Filipina, i Danielle Aldridge. Effectiveness of EHR-Depression Screening Among Adult Diabetics in an Urban Primary Care Clinic. University of Tennessee Health Science Center, kwiecień 2021. http://dx.doi.org/10.21007/con.dnp.2021.0003.

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Background Diabetes mellitus (DM) and depression are important comorbid conditions that can lead to more serious health outcomes. The American Diabetes Association (ADA) supports routine screening for depression as part of standard diabetes management. The PHQ2 and PHQ9 questionnaires are good diagnostic screening tools used for major depressive disorders in Type 2 diabetes mellitus (DM2). This quality improvement study aims to compare the rate of depression screening, treatment, and referral to behavioral health in adult patients with DM2 pre and post-integration of depression screening tools into the electronic health record (EHR). Methods We conducted a retrospective chart review on patients aged 18 years and above with a diagnosis of DM2 and no initial diagnosis of depression or other mental illnesses. Chart reviews included those from 2018 or prior for before integration data and 2020 to present for after integration. Sixty subjects were randomly selected from a pool of 33,695 patients in the clinic with DM2 from the year 2013-2021. Thirty of the patients were prior to the integration of depression screening tools PHQ2 and PHQ9 into the EHR, while the other half were post-integration. The study population ranged from 18-83 years old. Results All subjects (100%) were screened using PHQ2 before integration and after integration. Twenty percent of patients screened had a positive PHQ2 among subjects before integration, while 10% had a positive PHQ2 after integration. Twenty percent of patients were screened with a PHQ9 pre-integration which accounted for 100% of those subjects with a positive PHQ2. However, of the 10% of patients with a positive PHQ2 post-integration, only 6.7 % of subjects were screened, which means not all patients with a positive PHQ2 were adequately screened post-integration. Interestingly, 10% of patients were treated with antidepressants before integration, while none were treated with medications in the post-integration group. There were no referrals made to the behavior team in either group. Conclusion There is no difference between the prevalence of depression screening before or after integration of depression screening tools in the EHR. The study noted that there is a decrease in the treatment using antidepressants after integration. However, other undetermined conditions could have influenced this. Furthermore, not all patients with positive PHQ2 in the after-integration group were screened with PHQ9. The authors are unsure if the integration of the depression screens influenced this change. In both groups, there is no difference between referrals to the behavior team. Implications to Nursing Practice This quality improvement study shows that providers are good at screening their DM2 patients for depression whether the screening tools were incorporated in the EHR or not. However, future studies regarding providers, support staff, and patient convenience relating to accessibility and availability of the tool should be made. Additional issues to consider are documentation reliability, hours of work to scan documents in the chart, risk of documentation getting lost, and the use of paper that requires shredding to comply with privacy.
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Almost half those on long-term antidepressants did not relapse when they stopped their medication. National Institute for Health Research, marzec 2022. http://dx.doi.org/10.3310/alert_49876.

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Some antidepressants can help people quit smoking, but other medications may offer greater benefits. National Institute for Health Research, lipiec 2020. http://dx.doi.org/10.3310/alert_40474.

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