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Data publikacji: 25 lipca 2024

Data aktualizacji: 26 lipca 2024

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1

Kohan, Darius, Paul E. Hammerschlag i Roy A. Holliday. "Otologic Disease in AIDS Patients". Laryngoscope 100, nr 12 (grudzień 1990): 1326???1330. http://dx.doi.org/10.1288/00005537-199012000-00016.

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Weissler, Jonathan C., i Ann R. Mootz. "Pulmonary Disease in AIDS Patients". American Journal of the Medical Sciences 300, nr 5 (listopad 1990): 330–43. http://dx.doi.org/10.1097/00000441-199011000-00010.

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Hamm, Hinrich, i Heinrich Matthys. "Pleural disease in patients with AIDS". Current Opinion in Pulmonary Medicine 3, nr 4 (lipiec 1997): 315–18. http://dx.doi.org/10.1097/00063198-199707000-00014.

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Bini, Edmund J., i David L. Diehl. "Colonic disease in patients with AIDS". Techniques in Gastrointestinal Endoscopy 4, nr 2 (kwiecień 2002): 77–85. http://dx.doi.org/10.1053/tgie.2002.33010.

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McGill, Deborah, i W. D. Joseph. "An HIV/AIDS Awareness Prevention Project in Sri Lanka: Evaluation of Drama and Flyer Distribution Interventions". International Quarterly of Community Health Education 16, nr 3 (październik 1996): 237–55. http://dx.doi.org/10.2190/9ptk-f67j-nefc-7wgr.

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An evaluation was done on an AIDS Awareness Project targeting the West Coast of Sri Lanka. Dramas, performed primarily by volunteers, depicted the causes and consequences of HIV/AIDS. Flyers illustrating specific facts about HIV/AIDS were given at the dramas and at specific sites, such as bus stations. A pencil and paper pre-post design was used to evaluate the dramas and revealed that the primary respondent was an educated male who was very knowledgeable about basic HIV/AIDS information and had learned this primarily from the media (television and newspapers). Changes in attitude occurred as a result of the intervention, with respondents becoming more aware of their susceptibility to the disease and more willing to seek out advice from the Buddhist clergy if diagnosed with HIV/AIDS. The flyer distribution intervention revealed that brochures that address various levels of literacy may be more accepted by the general public.

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6

Zonta, Marise Bueno, Sérgio Monteiro de Almeida, Mirian T. M. de Carvalho i Lineu César Werneck. "Functional assesment of patients with AIDS disease". Brazilian Journal of Infectious Diseases 7, nr 5 (październik 2003): 301–6. http://dx.doi.org/10.1590/s1413-86702003000500004.

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Oelemann, Walter, Jorge N. Velásquez, Silvana Carnevale, Horacio Besasso, Maria G. M. Teixeira i José M. Peralta. "Intestinal Chagas' disease in patients with AIDS". AIDS 14, nr 8 (maj 2000): 1072. http://dx.doi.org/10.1097/00002030-200005260-00027.

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Volberding, Paul. "Treatment of malignant disease in AIDS patients". AIDS 2 (1988): S169–176. http://dx.doi.org/10.1097/00002030-198800001-00025.

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Navarro, Willis H., i Lawrence D. Kaplan. "AIDS-related lymphoproliferative disease". Blood 107, nr 1 (1.01.2006): 13–20. http://dx.doi.org/10.1182/blood-2004-11-4278.

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Abstract Not long after the recognition of HIV as the causative agent of AIDS, it was evident that individuals infected with HIV developed lymphoma at a greater rate than the population at large. Approximately two thirds of AIDS-related lymphoma (ARL) cases are categorized as diffuse large B-cell type, with Burkitt lymphomas comprising 25% and other histologies a much smaller proportion. Typically, these individuals have presented with advanced extranodal disease and CD4+ lymphocyte counts of less than 200/mm3. Recent clinical trials have demonstrated a better outcome with chemotherapy for ARL since the introduction of combination antiretroviral treatment, termed highly active antiretroviral therapy (HAART). For patients with relapses, solid evidence points to the safety and utility of hematopoietic-cell transplantation as a salvage modality. Coinfection with other viruses such as Epstein-Barr virus and Kaposi sarcoma-associated herpesvirus have led to the genesis of previously rare or unrecognized lymphoma subtypes such as plasmablastic and primary effusion lymphomas. The immunosuppressive impact of treatment for patients with ARL receiving chemotherapy with HAART appears transient and opportunistic infections have become less problematic than prior to HAART. Significant progress has been made in the understanding and management of ARL but outcomes still remain inferior compared to those achieved in HIV- individuals.

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10

Thomsen, Hauke, Xinjun Li, Kristina Sundquist, Jan Sundquist, Asta Försti i Kari Hemminki. "Familial associations for Addison’s disease and between Addison’s disease and other autoimmune diseases". Endocrine Connections 9, nr 11 (listopad 2020): 1114–20. http://dx.doi.org/10.1530/ec-20-0328.

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Design Addison’s disease (AD) is a rare autoimmune disease (AID) of the adrenal cortex, present as an isolated AD or part of autoimmune polyendocrine syndromes (APSs) 1 and 2. Although AD patients present with a number of AID co-morbidities, population-based family studies are scarce, and we aimed to carry out an unbiased study on AD and related AIDs. Methods We collected data on patients diagnosed with AIDs in Swedish hospitals and calculated standardized incidence ratios (SIRs) in families for concordant AD and for other AIDs, the latter as discordant relative risks. Results The number of AD patients was 2852, which accounted for 0.4% of all hospitalized AIDs. A total of 62 persons (3.6%) were diagnosed with familial AD. The SIR for siblings was remarkably high, reaching 909 for singleton siblings diagnosed before age 10 years. It was 32 in those diagnosed past age 29 years and the risk for twins was 323. SIR was 9.44 for offspring of affected parents. AD was associated with 11 other AIDs, including thyroid AIDs and type 1 diabetes and some rarer AIDs such as Guillain–Barre syndrome, myasthenia gravis, polymyalgia rheumatica and Sjögren’s syndrome. Conclusions The familial risk for AD was very high implicating genetic etiology, which for juvenile siblings may be ascribed to APS-1. The adult part of sibling risk was probably contributed by recessive polygenic inheritance. AD was associated with many common AIDs; some of these were known co-morbidities in AD patients while some other appeared to more specific for a familial setting.

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11

Kohan, Darius, Stephen G. Rothstein i Noel L. Cohen. "Otologic Disease in Patients with Acquired Immunodeficiency Syndrome". Annals of Otology, Rhinology & Laryngology 97, nr 6 (listopad 1988): 636–40. http://dx.doi.org/10.1177/000348948809700611.

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A 5-year retrospective study evaluating otologic disease in patients with acquired immunodeficiency syndrome (AIDS) was conducted at the New York University Medical Center-Bellevue Hospital Center. Twenty-six patients with documented otologic disease who met the Centers for Disease Control criteria for AIDS were identified and their charts were analyzed according to presenting complaints, physical examination, diagnostic modalities, pathologic condition, management, and outcome. A marked diversity of otologic diseases of varying severity was noted. The majority of patients complained of hearing loss and otalgia during their hospitalization for treatment of AIDS-related opportunistic infections. The most frequent diagnoses were otitis externa, acute otitis media, and otitis media with effusion. Sensorineural hearing loss frequently appeared to be related to ototoxic medications and neurologic infections.

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12

Burke, Don G., Steven N. Emancipator, Michael C. Smith i Robert A. Salata. "Histoplasmosis and Kidney Disease in Patients with AIDS". Clinical Infectious Diseases 25, nr 2 (sierpień 1997): 281–84. http://dx.doi.org/10.1086/514556.

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Santos, Edwiges, Andre Japiassu, Marcia Lazera i Fernando Bozza. "Fungal disease in AIDS patients in intensive care". Critical Care 17, Suppl 4 (2013): P41. http://dx.doi.org/10.1186/cc12941.

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14

Mhiri, Chokri, Laurent Bélec, Bernard Di Costanzo, Alain Georges i Romain Gherardi. "The slim disease in African patients with AIDS". Transactions of the Royal Society of Tropical Medicine and Hygiene 86, nr 3 (maj 1992): 303–6. http://dx.doi.org/10.1016/0035-9203(92)90323-5.

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15

Benson, Constance A. "Mycobacterium avium Complex Disease in Patients With AIDS". Infectious Diseases in Clinical Practice 4, nr 1 (styczeń 1995): 1–10. http://dx.doi.org/10.1097/00019048-199501000-00001.

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16

Petros Kelkile, Desalegn. "Statistical Analysis of Adult HIV/AIDS Patients and Modelling of AIDS Disease Progression". Science Journal of Applied Mathematics and Statistics 4, nr 5 (2016): 189. http://dx.doi.org/10.11648/j.sjams.20160405.12.

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17

Wilcox, C. Mel, i Klaus E. Mönkemüller. "Hepatobiliary Diseases in Patients with AIDS: Focus on AIDS Cholangiopathy and Gallbladder Disease". Digestive Diseases 16, nr 4 (1998): 205–13. http://dx.doi.org/10.1159/000016868.

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18

Cheong, I., P. J. Flegg, R. P. Brettle, P. D. Welsby, S. M. Burns, B. Dhillon, C. L. S. Leen i J. A. Gray. "Cytomegalovirus Disease in AIDS: The Edinburgh Experience". International Journal of STD & AIDS 3, nr 5 (wrzesień 1992): 324–28. http://dx.doi.org/10.1177/095646249200300504.

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Retrospective analysis of medical records of 557 HIV positive patients (including 113 with AIDS) revealed 17 patients with an antemortem clinical diagnosis of cytomegalovirus (CMV) disease. This group comprised 7 injection drug users (2 male and 5 female) and 10 homosexual men. Males were significantly older than females, and homosexual men were significantly older than drug users at the time of diagnosis of CMV. All 17 patients had evidence of retinitis, and 6 also had evidence of extraocular disease. CMV retinitis was the AIDS defining diagnosis in two patients, and the attack rate of CMV in all AIDS patients progressively increased with time, with a 3-year CMV-free survival of 57%. Fifteen patients with CMV disease had evidence of previous CMV infection (CMV IgG positive), with 7 also having a positive CMV IgM and 10 a positive viral culture. The mean CD4+ lymphocyte count at diagnosis of CMV was 17 cells/mm3, compared with 68 cells/mm3 at diagnosis of AIDS. Therapy was unsatisfactory, often being complicated by marrow suppression. Relapse occurred in 11 patients after initial improvement but despite this only 3 patients died with severe visual impairment. The mean survival after a diagnosis of CMV was 10.5 months. This study confirms that disease caused by CMV is usually a late manifestation of AIDS, and the increasing prevalence among patients with AIDS implies that, the longer the survival, the greater the risk of disease. Frequent fundoscopy in HIV positive patients is of paramount importance particularly in patients who have a CD4+ lymphocyte count of less than 100 cells/mm3.

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19

Stuart, Rhonda L., Margaret E. Hellard, Damien Jolley, Denis Spelman, Jennifer Hoy, Elaine M. Stevenson, Maria T. Yates, Norbert J. Ryan i Christopher K. Fairley. "Cryptosporidiosis in patients with AIDS". International Journal of STD & AIDS 8, nr 5 (1.05.1997): 339–41. http://dx.doi.org/10.1258/0956462971920064.

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Cases of cryptosporidiosis in patients with the acquired immunodeficiency syndrome (AIDS) residing in Melbourne over a 6-year period (1990-1995) are described. During this period 85 cases occurred, while 979 new AIDS diagnoses were notified. Over this period temporal clustering in cryptosporidial detection was evident ( P =0.007), but the pattern was not statistically associated with the season, rainfall ( P =0.88), mean average maximal temperature ( P =0.15) or mean average minimal temperature. Further studies should identify these risk factors and provide an opportunity to prevent this devastating disease.

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20

Khondker, Lubna. "Dermatological Manifestations of HIV/AIDS Patients". Journal of Enam Medical College 9, nr 3 (22.09.2019): 185–88. http://dx.doi.org/10.3329/jemc.v9i3.43249.

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Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/ AIDS) is a global pandemic. According to Global HIV & AIDS statistics 2018, approximately 36.9 million people are living with HIV globally, 77.3 million [59.9 million–100 million] people have become infected with HIV since the start of the epidemic, 35.4 million [25.0–49.9 million] people died from AIDS-related illnesses since the start of the epidemic and 940000 [670000–1.3 million] people died from AIDS-related illnesses in 2017. It weakens a person’s immune system by destroying important cells that fight disease and infection. Dermatologic diseases are common in the HIV-infected population. Skin disease can be uniquely associated with HIV disease and many of the cutaneous diseases are not unique to this group, but the presentation can be more severe and recalcitrant to treatment. The spectrum of skin conditions includes skin findings associated with primary HIV infection and a broad range of skin problems related to the immune deficiency of advanced AIDS. Recognition of characteristic eruptions can facilitate early diagnosis of HIV. A broad variety of neoplastic, infectious and non-infectious diseases can manifest in the skin and may alert the clinician of declining of the immune system. This article reviews the current spectrum of HIV-associated skin conditions, focusing on common complaints, infections, drugassociated toxicity and malignancies based on recently published literature relevant to this area. J Enam Med Col 2019; 9(3): 185-188

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21

Xie, Erfu, Zhongjian Zhao, Chengjing Yan, Yiting Zhang, Qiaodi Zhang i Shiyang Pan. "Different vitamin D status in common multiorgan autoimmune disease patients". Journal of Laboratory Medicine 43, nr 5 (25.10.2019): 243–47. http://dx.doi.org/10.1515/labmed-2019-0104.

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Abstract Background Vitamin D plays a key role in calcium homeostasis and contributes to the regulation of the immune system. Furthermore, vitamin D deficiency has been reported to be associated with autoimmune diseases (AIDs), especially with multiorgan AIDs. Various multiorgan AIDs may be different based on the vitamin D status. This study aims to investigate the serum 25-hydroxyvitamin D (25(OH)D) levels in patients with different common multiorgan AIDs. Methods A total of 295 patients with multiorgan AIDs treated in our hospital from January 2012 to September 2018 were recruited, including 137 cases of rheumatoid arthritis (RA), 85 cases of systemic lupus erythematosus (SLE), 32 cases of Sjögren’s syndrome (SS) and 41 cases of mixed connective tissue disease (MCTD); 47 apparently healthy individuals were also recruited as controls. The serum 25(OH)D levels in patients with different multiorgan AIDs were measured with Roche electrochemiluminescence immunoassay and statistically analyzed the proportion of patients with normal, insufficiency and deficiency in 25(OH)D levels in different multiorgan diseases. The 25(OH)D levels of different multiorgan AID groups and healthy controls were also compared. Results Incidences of 25(OH)D deficiency in the RA, SLE, SS and MCTD groups were 21.2%, 35.3%, 25.0% and 22.0%, respectively, with significant inter-group differences (p < 0.05). The incidence in the SLE group was higher than in the RA, SS and MCTD groups, indicating severe 25(OH)D deficiency in patients with SLE. Significant inter-group differences (p < 0.05) were detected in the serum 25(OH)D levels in different multiorgan AID groups and in the healthy control group. Further pairwise comparison found a significantly higher level of 25(OH)D in the healthy control group than in the SLE, SS, RA and MCTD groups (p < 0.05). Moreover, the 25(OH)D status in the SLE group was significantly lower than that in the SLE, SS, RA and MCTD groups (p < 0.05). Conclusions Serum 25(OH)D deficiency and a low 25(OH)D status are commonly seen in patients with different multiorgan AIDs compared to healthy controls, warranting vitamin D supplementation. Severe 25(OH)D deficiency and a lower 25(OH)D status were found in patients with SLE.

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&NA;. "Clarithromycin treats M. avium disease in patients with AIDS". Inpharma Weekly &NA;, nr 969 (styczeń 1995): 15. http://dx.doi.org/10.2165/00128413-199509690-00026.

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Sargent, Juliet, i Eileen Nixon. "IV access options for AIDS patients with cytomegalovirus disease". British Journal of Nursing 6, nr 10 (22.05.1997): 543–53. http://dx.doi.org/10.12968/bjon.1997.6.10.543.

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., V. Nissapatorn, C. K. C. Lee ., Y. A. L. Lim ., K. S. Tan ., I. Jamaiah ., M. Rohela ., B. L. H. Sim . i in. "Toxoplasmosis: A Silent Opportunistic Disease in HIV/AIDS Patients". Research Journal of Parasitology 2, nr 1 (1.01.2007): 23–31. http://dx.doi.org/10.3923/jp.2007.23.31.

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Corr, Peter D. "Imaging of Cerebrovascular and Cardiovascular Disease in AIDS Patients". American Journal of Roentgenology 187, nr 1 (lipiec 2006): 236–41. http://dx.doi.org/10.2214/ajr.05.0190.

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Jacobson, Mark A. "Current Management of Cytomegalovirus Disease in Patients with AIDS". AIDS Patient Care 9, nr 1 (luty 1995): 10–17. http://dx.doi.org/10.1089/apc.1995.9.10.

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BENSON, CONSTANCE. "Disseminated Mycobacterium avium Complex Disease in Patients with AIDS". AIDS Research and Human Retroviruses 10, nr 8 (sierpień 1994): 913–16. http://dx.doi.org/10.1089/aid.1994.10.913.

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JACOBSON, MARK A. "Current Management of Cytomegalovirus Disease in Patients with AIDS". AIDS Research and Human Retroviruses 10, nr 8 (sierpień 1994): 917–23. http://dx.doi.org/10.1089/aid.1994.10.917.

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Bonacini, Maurizio, i Loren A. Laine. "Esophageal Disease in Patients with AIDS: Diagnosis and Treatment". Gastrointestinal Endoscopy Clinics of North America 8, nr 4 (październik 1998): 811–23. http://dx.doi.org/10.1016/s1052-5157(18)30233-2.

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Winston, Jonathan, Gilbert Deray, Trevor Hawkins, Lynda Szczech, Christina Wyatt i Benjamin Young. "Kidney Disease in Patients with HIV Infection and AIDS". Clinical Infectious Diseases 47, nr 11 (grudzień 2008): 1449–57. http://dx.doi.org/10.1086/593099.

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Guazzelli, Luciana Silva, Gisela Unis, Melissa Orzechowski Xavier, Cecília Bittencourt Severo, Pedro Dornelles Picon i Luiz Carlos Severo. "Fungus ball in HIV-infected patients". Revista do Instituto de Medicina Tropical de São Paulo 51, nr 6 (grudzień 2009): 345–48. http://dx.doi.org/10.1590/s0036-46652009000600007.

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Aspergillus is a phagocyte opportunistic fungus that causes aspergillosis, an unusual disease in patients with AIDS. Six cases of fungal ball in patients with AIDS are reported here. In this group, all patients had hemoptysis and tuberculosis as the underlying lung disease. The diagnosis of pulmonary fungus ball was based on the clinical and radiographic feature, combined with serological and mycological evidence of Aspergillus fumigatus.

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Samuels, Hadas, Malki Malov, Trishna Saha Detroja, Karin Ben Zaken, Naamah Bloch, Meital Gal-Tanamy, Orly Avni, Baruh Polis i Abraham O. Samson. "Autoimmune Disease Classification Based on PubMed Text Mining". Journal of Clinical Medicine 11, nr 15 (26.07.2022): 4345. http://dx.doi.org/10.3390/jcm11154345.

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Autoimmune diseases (AIDs) are often co-associated, and about 25% of patients with one AID tend to develop other comorbid AIDs. Here, we employ the power of datamining to predict the comorbidity of AIDs based on their normalized co-citation in PubMed. First, we validate our technique in a test dataset using earlier-reported comorbidities of seven knowns AIDs. Notably, the prediction correlates well with comorbidity (R = 0.91) and validates our methodology. Then, we predict the association of 100 AIDs and classify them using principal component analysis. Our results are helpful in classifying AIDs into one of the following systems: (1) gastrointestinal, (2) neuronal, (3) eye, (4) cutaneous, (5) musculoskeletal, (6) kidneys and lungs, (7) cardiovascular, (8) hematopoietic, (9) endocrine, and (10) multiple. Our classification agrees with experimentally based taxonomy and ranks AID according to affected systems and gender. Some AIDs are unclassified and do not associate well with other AIDs. Interestingly, Alzheimer’s disease correlates well with other AIDs such as multiple sclerosis. Finally, our results generate a network classification of autoimmune diseases based on PubMed text mining and help map this medical universe. Our results are expected to assist healthcare workers in diagnosing comorbidity in patients with an autoimmune disease, and to help researchers in identifying common genetic, environmental, and autoimmune mechanisms.

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Kourkouta, L., A. Monios, Ch Iliadis i P. Ouzounakis. "AIDS and nutrition in patients". Progress in Health Sciences 7, nr 1 (25.05.2017): 0. http://dx.doi.org/10.5604/01.3001.0010.1881.

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Introduction: AIDS is a viral infection that particularly affects the nutritional status of patients by complicating the absorption of nutrients and their metabolism. Purpose: The purpose of this retrospective study is to highlight the contribution of nutrition to the wellness of people with HIV in all stages of the disease. Review Methods: The methodology used to select the information used in this study includes review studies and research in leading databases such as PUBMED, MEDLINE, and IATROTEK. The selection criterion of the articles was the Greek and English language.Results: The real goal of the nutritional assessment of patients with AIDS is to improve their ability to consume a sufficient quantity and variety of foods in order to meet their nutritional needs. The evaluation of dietary intake assesses the adequacy of food and nutrients consumed. It includes assessing the dietary patterns, frequency of meals, and the factors that affect food choice. Conclusions: Maintaining a good nutritional status has a significant impact on the functioning of the immune system and the overall health of people living with HIV / AIDS.

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Goodier, Martin R., C. M. Mela, A. Steel, B. Gazzard, M. Bower i F. Gotch. "NKG2C+ NK Cells Are Enriched in AIDS Patients with Advanced-Stage Kaposi's Sarcoma". Journal of Virology 81, nr 1 (11.10.2006): 430–33. http://dx.doi.org/10.1128/jvi.01567-06.

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ABSTRACT Kaposi's sarcoma (KS) is an AIDS-defining condition in individuals with human immunodeficiency virus type 1 infection. We investigated the phenotype and function of the NKG2C+ NK cell population in individuals with AIDS and Kaposi's sarcoma. The staging of AIDS KS patients according to the AIDS Clinical Trial Group criteria revealed that patients with the S1 disease stage have a significantly higher proportion of NKG2C+ cells than those with the S0 disease stage. NKG2C+ cells from S1-stage patients are highly enriched for the expression of KIR3DL1, are depleted of NKp46, and respond poorly to major histocompatibility complex class I-positive target cells. These data demonstrate a link between NK cell phenotype and function and disease prognosis in AIDS.

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White, M., C. Cirrincione, A. Blevins i D. Armstrong. "Cryptococcal Meningitis: Outcome in Patients with AIDS and Patients with Neoplastic Disease". Journal of Infectious Diseases 165, nr 5 (1.05.1992): 960–63. http://dx.doi.org/10.1093/infdis/165.5.960.

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Sodhi, Punita Kumari. "Orbital manifestations in patients with acquired immunodeficiency syndrome". Nepalese Journal of Ophthalmology 6, nr 2 (13.12.2014): 205–19. http://dx.doi.org/10.3126/nepjoph.v6i2.11710.

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Introduction: The orbital manifestations of acquired immunodeficiency syndrome (AIDS) are uncommon.Objective: To provide a review of orbital manifestations of AIDS, the predisposing factors, investigations, treatment and outcome. Materials and methods: Meticulous and systematic literature search of Pubmed to identify manuscripts describing orbital manifestations of AIDS was done and the articles were reviewed. The keywords used in the search were “orbit and AIDS”, “HIV positive and orbit”, “orbit manifestations in AIDS”, “orbital disease and AIDS” and “orbital infections and AIDS”. The orbital involvement in AIDS may present with opportunistic infections from organisms like fungi, viruses, bacteria and protozoa or with malignancies like Kaposi’s sarcoma, squamous cell carcinoma, smooth muscle cell tumors and lymphoma. The predisposing factors for orbital involvement in AIDS are low CD4+ cell count and the immunosuppressive states like diabetes, diabetic ketoacidosis, intravenous drug abuse and neutropenia. A patient may present with fever, headache, nausea, vomiting, decreased vision, ocular pain, and, in cases of mass formation, there is periorbital swelling, axial proptosis, globe displacement and swollen optic disc. Radiologically, mass formation, orbital bony destruction, and spread of disease to contiguous structures including the central nervous system may be seen. The medical management includes therapy for infection and HIV-1 protease inhibitors (highly active antiretroviral therapy) to suppress HIV-1 replication. For tumors, radical surgery including debulking followed by postoperative radiotherapy is generally needed. Conclusion: Orbital involvements with AIDS in any form, infective or malignancy, causes significant morbidity and mortality and should be diagnosed and managed as early as possible.DOI: http://dx.doi.org/10.3126/nepjoph.v6i2.11710Nepal J Ophthalmol 2014; 6(12): 205-219

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Chen, Yahong, Jinjin Yuan, Xianlin Han, Xiaolong Liu, Xiao Han i Hanhui Ye. "Coexpression Analysis of Transcriptome on AIDS and Other Human Disease Pathways by Canonical Correlation Analysis". International Journal of Genomics 2017 (2017): 1–10. http://dx.doi.org/10.1155/2017/9163719.

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Acquired immune deficiency syndrome is a severe disease in humans caused by human immunodeficiency virus. Several human genes were characterized as host genetic factors that impact the processes of AIDS disease. Recent studies on AIDS patients revealed a series disease is complicating with AIDS. To resolve gene interaction between AIDS and complicating diseases, a canonical correlation analysis was used to identify the global correlation between AIDS and other disease pathway genes expression. The results showed that HLA-B, HLA-A, MH9, ZNED1, IRF1, TLR8, TSG101, NCOR2, and GML are the key AIDS-restricted genes highly correlated with other disease pathway genes. Furthermore, pathway genes in several diseases such as asthma, autoimmune thyroid disease, and malaria were globally correlated with ARGs. It suggests that these diseases are a high risk in AIDS patients as complicating diseases.

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Yaro*, Abubakar, Edmund Puca i Catherine Johnson. "Strategies for Improving Adherence in Patients with HIVAIDS". Journal of Biomedical Research & Environmental Sciences 4, nr 12 (grudzień 2023): 1675–83. http://dx.doi.org/10.37871/jbres1851.

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Human Immunodeficiency Virus (HIV)-1 is the cause of Acquired Immunodeficiency Syndrome (AIDS). Due to advances in clinical management, HIV/AIDS is now regarded a chronic disease instead of terminal disease. However, non-adherence is a challenge in effective management of HIV/AIDS. Non-adherence is classified into intentional and unintentional non-adherence Interactive toxicity belief is now one of the main factors that promotes non-adherence among HIV patients. Detecting non-adherence is an essential component of managing this phenomenon. A number measures has been proposed on how to manage non-adherence Optimum non-adherence-preventing measures should be holistic that involve different strategies. This review suggest MIB+ model for tackling non-adherence among HIV/AIDS patients. We also need to have more understanding on how stigma implicates non-adherence.

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Goodman, David S., Ellen D. Teplitz, Amy Wishner, Robert S. Klein, Peter G. Burk i Esther Hershenbaum. "Prevalence of cutaneous disease in patients with acquired immunodeficiency syndrome (AIDS) or AIDS-related complex". Journal of the American Academy of Dermatology 17, nr 2 (sierpień 1987): 210–20. http://dx.doi.org/10.1016/s0190-9622(87)70193-5.

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Hutcheon, Linda, i Michael Hutcheon. "Syphilis, sin and the social order: Richard Wagner'sParsifal". Cambridge Opera Journal 7, nr 3 (listopad 1995): 261–75. http://dx.doi.org/10.1017/s0954586700004596.

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In the age of AIDS, few would be surprised to find sexuality connected to suffering and disease; in the age of syphilis – from its arrival in Europe in 1492 to today, when it is on the rise once again – the connection is equally strong, though many of us have forgotten this. The brief respite offered by the discovery of a cure for syphilis (through the use of penicillin) in the 1940s ended with the appearance of AIDS. Over the last five hundred years, the Christian reading of syphilis as the scourge of God directed against the sexually sinful has merged with societal sexual anxieties about the effects of syphilis on the general social fabric and, in the nineteenth and twentieth centuries, on the family in particular. The perhaps surprising focus of this discussion (by a literary theorist and a physician) of suffering and social decline in the context of sexually transmitted disease is Richard Wagner's last music drama,Parsifal, finally completed in 1882 and called aBühnenweihfestspiel(a stage consecration festival play) for his Bayreuth theatre.

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Morris, Ashley K., i Amy Wells Valley. "Overview of the Management of AIDS-Related Kaposi's Sarcoma". Annals of Pharmacotherapy 30, nr 10 (październik 1996): 1150–63. http://dx.doi.org/10.1177/106002809603001015.

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OBJECTIVE: To review the epidemiology, pathogenesis, clinical presentation, diagnosis, and staging of Kaposi's sarcoma (KS), as well as the current role of local and systemic therapies in the management of AIDS-related KS (AIDS–KS). DATA SOURCES AND STUDY SELECTION: MEDLINE and CANCERLIT searches of the English-language medical literature were conducted. Emphasis was placed on studies published since the onset of the AIDS epidemic in the early 1980s. A manual review of selected bibliographies was also completed. DATA SYNTHESIS: AIDS–KS is a disease with a heterogeneous presentation that affects approximately 20% of patients with AIDS. Although the proportion of AIDS patients developing this disease during the course of their illness is declining, the actual number of AIDS–KS cases is increasing. The etiology of AIDS–KS is not clear, but a sexually transmitted cofactor has been implicated. Recent reports demonstrate that a herpes-like virus may be responsible for the development of KS in patients with and without AIDS. Furthermore, the cellular origin of KS has not been identified and questions remain about whether KS represents a true malignancy. The system used in staging patients with AIDS–KS has changed dramatically since initial therapeutic trials were conducted; this may account for observed differences in outcome among trials. The immunologic status of patients is now included as part of the staging system, since it has prognostic significance. Since specific therapy for AIDS–KS is not curative and does not prolong survival, it should be directed at improving patient cosmesis and palliation of disease-related symptoms. Local therapy, such as radiation, cryotherapy, and intralesional chemotherapy, is recommended for the management of limited disease. Systemic interferon alfa or chemotherapy is indicated for disseminated disease. Interferon alfa is useful in patients with predominantly mucocutaneous disease and is most effective in patients with good prognostic factors, such as absence of B symptoms, no history of opportunistic infections, and a CD4 count of more than 200 cells/mm3. Interferon alfa alone or in combination with zidovudine produces responses in approximately 30% of AIDS–KS patients with good prognostic factors. Single-agent or combination chemotherapy is indicated for rapidly progressive or advanced AIDS–KS. Commonly used agents include doxorubicin, daunorubicin, bleomycin, vincristine, and vinblastine. Responses can be expected in at least 50% of patients treated with single-agent or combination chemotherapy. However, many patients are unable to tolerate the toxicity associated with systemic AIDS–KS therapy. Future research will focus on therapies that target the underlying pathogenesis of this disease. CONCLUSIONS: The optimal therapy for patients with AIDS–KS has not been determined. Treatment is appropriately directed at palliation of disease-related symptoms as no therapy has been unequivocally proven to impact survival. Local therapies should be used in the management of localized disease, while systemic therapy is appropriate for disseminated disease. Interferon alfa is useful in patients with primarily mucocutaneous disease or asymptomatic visceral involvement. Chemotherapy is indicated in patients who have rapidly progressive or advanced disease. Therapy must be individualized according to the patient's disease course and other patient-specific factors.

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Prado-Calleros, Héctor M., Bertha B. Castillo-Ventura, Irma Jiménez-Escobar, Juan P. Ramírez-Hinojosa, Antonio López-Gómez, Miguel García-de-la-Cruz i Mijal Dayan-Nurko. "Noma and Noma-like disease in HIV/AIDS patients, a comorbid interaction: A systematic review". Journal of Infection in Developing Countries 12, nr 02 (28.02.2018): 89–96. http://dx.doi.org/10.3855/jidc.9716.

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Introduction: Noma is an opportunistic polymicrobial infection that cause necrosis of the mouth and face, with high morbidity and mortality, predominantly affecting malnourished children and persons with debilitating diseases. Cases of noma-like disease in adults, although rare, have been increasingly reported in HIV/AIDS patients particularly in developing countries but also in more developed countries. Methodology: A systematic review of the literature to assess the occurrence and clinical impact of noma and noma-like disease in HIV/AIDS patients was performed on PubMed, Virtual Health Library, Cochrane Library and Google Scholar using the keywords "HIV"[ All Fields] AND "Noma"[All Fields] in December 2016 (years includead for the search: 1985 to 2016). Results: Twenty-four published studies were identified that document the occurrence of noma or noma-like disease in a total of 133 HIV/AIDS children and adult patients in the last 22 years. Although HIV infection is not the principal risk factor for noma, in some regions may play a substantial role in its pathogenesis. The mortality rate for noma-like disease in HIV/AIDS patients was 54.3%, compared to the 15% mortality rate of treated noma patients without HIV/AIDS. Most of the cases have never been on antiretroviral therapy, and their HIV infection was discovered because of the noma-like disease. Conclusions: The syndemic interaction between HIV/AIDS and noma-like disease adversely impacts the severity of the disease and the mortality rate. Noma-like disease, although not yet considered a specific or frequent disease associated with HIV infection, should be considered as an opportunistic infection for AIDS.

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Coker, R. J., i D. M. Mitchell. "The Role of Bronchoscopy in Patients with HIV Disease". International Journal of STD & AIDS 5, nr 3 (maj 1994): 172–76. http://dx.doi.org/10.1177/095646249400500303.

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Pulmonary involvement is a frequent feature of patients infected with the human immunodeficiency virus (HIV). Pneumocystis carinii pneumonia (PCP) is still the commonest AIDS defining diagnosis despite the advent of effective prophylaxis and antiretroviral treatment. Other pulmonary manifestations of AIDS, including tuberculosis, may pose a greater problem in the future. The clinical manifestations of HIV-disease are many and varied, and changing as the disease is modified by therapeutic interventions. With specific and increasingly effective treatments the need for definitive diagnosis is obvious. Fibreoptic bronchoscopy is a well established tool for the diagnosis of HIV-related pulmonary complications. This article aims to give an account on the use of bronchoscopy in a unit providing care for many HIV seropositive patients.

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Paltiel, A. David, i Kenneth A. Freedberg. "The Cost-Effectiveness of Preventing Cytomegalovirus Disease in AIDS Patients". Interfaces 28, nr 3 (czerwiec 1998): 34–51. http://dx.doi.org/10.1287/inte.28.3.34.

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Manabe, Y. C., D. P. Clark, R. D. Moore, Lumadue, H. R. Dahlman, P. C. Belitsos, R. E. Chaisson i C. L. Sears. "Cryptosporidiosis in Patients with AIDS: Correlates of Disease and Survival". Clinical Infectious Diseases 27, nr 3 (1.09.1998): 536–42. http://dx.doi.org/10.1086/514701.

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Pursell, K. J., E. E. Telzak i D. Armstrong. "Aspergillus Species Colonization and Invasive Disease in Patients with AIDS". Clinical Infectious Diseases 14, nr 1 (1.01.1992): 141–48. http://dx.doi.org/10.1093/clinids/14.1.141.

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Buckner, F. S., i C. Pomeroy. "Cytomegalovirus Disease of the Gastrointestinal Tract in Patients Without AIDS". Clinical Infectious Diseases 17, nr 4 (1.10.1993): 644–56. http://dx.doi.org/10.1093/clinids/17.4.644.

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&NA;. "Gallium scintigraphy effectively detects secondary disease in patients with AIDS". Inpharma Weekly &NA;, nr 747 (lipiec 1990): 20. http://dx.doi.org/10.2165/00128413-199007470-00057.

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Albin, Jorge, Errol Lewis, Farzin Eftekhari i Ali Shirkhoda. "Computed tomography of rectal and perirectal disease in AIDS patients". Gastrointestinal Radiology 12, nr 1 (grudzień 1987): 67–70. http://dx.doi.org/10.1007/bf01885105.

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Cline, Julie J., i Anna D. Garrett. "Combination Antiviral Therapy for Cytomegalovirus Disease in Patients with AIDS". Annals of Pharmacotherapy 31, nr 9 (wrzesień 1997): 1080–82. http://dx.doi.org/10.1177/106002809703100919.

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Currently, combination therapy with ganciclovir and foscarnet should be reserved for patients with disease progression while receiving monotherapy or for those who are unresponsive to either agent alone. Although cidofovir and ganciclovir were shown to have synergistic activity against human CMV in vitro, there have been no in vivo studies to confirm this activity. Therefore, if a combination regimen is necessary to control CMV in a patient, foscarnet and ganciclovir should be used first. There are several advantages of the combination therapy regimen. For instance, lower doses of the individual agents can be used with superior efficacy to monotherapy and similar toxicities.5,10 Also, for neurologic CMV involvement, the combination therapy may be superior to monotherapy because of the variable CSF penetration of either drug alone. In addition, combined therapy may be beneficial in treating and/or preventing drug-resistant strains of CMV.13 Even though combination therapy has evidence of superior efficacy compared with monotherapy in the treatment of CMV, several issues must be considered. First, combination therapy has longer administration times because of the infusion of multiple drugs, which may be an inconvenience. Also, even though the toxic effects are similar with both combined therapy and monotherapy, the adverse effects associated with combination therapy may be less well tolerated and may negatively affect the patient's quality of life. Finally, combination therapy is more expensive than monotherapy with ganciclovir or foscarnet alone.10 Patients should be evaluated with these issues in mind before combination therapy is initiated.

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