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1
Limb, Mark. "Evaluating the implementation of compact activity centres in greater Brisbane". Thesis, Queensland University of Technology, 2019. https://eprints.qut.edu.au/136081/1/Mark_Limb_Thesis.pdf.
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Over the past 20 years metropolitan plans have attempted to improve urban sustainability by reshaping Australian cities to include a network of compact activity centres. This research provides the first long-term and comprehensive evaluation of the implementation of greater Brisbane's activity centre policies and finds that although the plans were used as intended, they failed to achieve the desired outcomes. The research raises doubts about the current Australian planning system's capability to deliver on its core promises to reshape urban development. These results have implications for how planning can best contribute to improving urban sustainability.
2
Brewin, Ross, i ross brewin@rmit edu au. "Mediating Pressure, Facilitating Exchange: 3 Architectural Projects in Pressured Urban Environments". RMIT University. Architecture and Design, 2007. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080215.154127.
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The aim of the research is to demonstrate architectural design strategies and outcomes that provide alternative ways of considering the futures of areas under high developmental pressure. These areas are where the potential detrimental effects of unmediated, rapid change and development are at their most immediate and in need of consideration. Urban environments are complex physical manifestations of economic, environmental, social, cultural and political pressures represented by the often competing desires of public and private interest groups. Given the enormity of scale and complexity of these pressures, it is problematic to think of architecture as something that can design everything (perhaps as seen in traditional master planning) and in doing so, solve the problem. What may be more constructive is the consideration of architecture having the potential to be involved strategically in these issues, over a number of scales to work towards positive outcomes for the public domain. In recent years, both Victorian and Queensland state governments have released policy guiding the future growth of key regions within their borders. Each attempts to address accommodating large population increases over relatively short time periods by proposing consolidation in and around existing urban centres. This consolidation is seen as part of a strategy to limit urban sprawl and curtail its associated negative social, environmental and potential economic impacts. These targeted 'Activity Centres' become places of immanent transformation, points of pressure within the disaggregated field of the contemporary Australian city. Left un-mediated, developmental pressure in locations such as these is likely to create the same detrimental physical and social effects evident in the general prevailing homogeneity, commercialisation and piecemeal nature of current urban development. Through several architectural design projects, the research aims to explore the role of architecture as an urban mediator within these pressured locations. Through bridging scales from the broad metropolitan, to the finer grained specific, this mediation may begin to strategically 'set things up' for the public domain, towards facilitating valuable social exchange.
3
Wong, Kin-on Leo, i 王健安. "Evaluation on training programs of day activity centres for mentally handicapped adults". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1991. http://hub.hku.hk/bib/B31976785.
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Gillespie, Charles William Ian. "Activity and life satisfaction in the elderly : a study at seniors' centres". Master's thesis, University of Cape Town, 1994. http://hdl.handle.net/11427/13474.
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Bibliography: leaves 82-89.Although the activity theory of optimal ageing has attracted much interest amongst psychological gerontologists since its explication by Havighurst and Albrecht {1953), little work has been done in the South African context. As the many seniors' centres which now exist in South Africa have the beneficial effects of heightened life satisfaction through improved social activity as their rationale, a study was undertaken at six seniors' centres in Cape Town to examine the connection between social activity and life satisfaction.
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Wong, Kin-on Leo. "Evaluation on training programs of day activity centres for mentally handicapped adults". [Hong Kong : University of Hong Kong], 1991. http://sunzi.lib.hku.hk/hkuto/record.jsp?B13064782.
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Brandt, William Nielsen. "Aspects of soft X-ray activity in the centres of radio-quiet active galaxies". Thesis, University of Cambridge, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242938.
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邵伊華 i Eva Siu. "Physical activity and physical performance in elderly health centres elderly with knee osteoarthritis in Hong Kong". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41711920.
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Siu, Eva. "Physical activity and physical performance in elderly health centres elderly with knee osteoarthritis in Hong Kong". Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B41711920.
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Ollagnier-de, Choudens Sandrine. "La ribonucléotide réductase anaérobie d'E. Coli : caractérisation et étude de ses centres redox". Université Joseph Fourier (Grenoble ; 1971-2015), 1997. http://www.theses.fr/1997GRE10255.
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Il n'y a dans le monde vivant qu'une seule voie conduisant a la biosynthese des desoxyribonucleotides, composants de base des chaines de l'adn : la reduction des ribonucleotides correspondants. Cette reaction essentielle est catalysee par une proteine radicalaire, la ribonucleotide reductase (rnr). A l'heure actuelle on connait 3 classes de rnrs. Les classes i et ii, representees par la rnr aerobie d'e. Coli et la rnr de l. Leichmanii sont assez bien caracterisees. La classe iii, mise en evidence chez escherichia coli, est representative des rnrs anaerobies. Sa caracterisation et l'etude de ses centres redox sont presentees dans ce manuscrit. La rnr anaerobie est constituee de deux sous-unites et (codees respectivement par les genes nrdd et nrdg) organisees sous la forme d'un complexe stable #2#2. La petite sous-unite #2 est une metalloproteine contenant un centre 2fe-2s par chaine. La grande sous-unite #2 contient un radical libre, localise sur le residu glycine 681. Ce radical est essentiel a l'activite et est extremement sensible a l'oxygene. La formation du radical glycinyle implique plusieurs cofacteurs et partenaires proteiques : un systeme reducteur (flavodoxine, nadph : flavodoxine oxydo-reductase), du dithiothreitol (dtt), de la s-adenosylmethionine (adomet) et le centre fer-soufre de #2. Lors de la reduction du centre fe-s par le systeme reducteur, les centres 2fe-2s des chaines s'associent pour former un centre 4fe-4s localise a l'interface des deux chaines. Ce processus n'a pas de precedent en biologie. L'agregat 4fe-4s interagit avec une molecule d'adomet pour former un complexe stable. En presence de dtt, le centre fe-s transfert ses electrons a l'adomet. Il en resulte une coupure de l'adomet conduisant a la formation de methionine, de 5'-desoxyadenosine et du radical glycinyle. C'est le premier exemple de la participation d'un centre fer-soufre dans une fonction de catalyse redox. Une fois radicalisee, l'enzyme catalyse la reaction de reduction des ribonucleosides triphosphates en desoxyribonucleotides correspondants. Lorsque le cycle catalytique est termine, des reducteurs externes regenerent les equivalents reducteurs necessaires a la reaction. Alors que les classes i et ii utilisent la thioredoxine ou la glutaredoxine, la classe iii utilise le formiate. Les mecanismes d'activation et de reduction de la rnr anaerobie presentent des similitudes avec ceux des classes i et ii : existence d'un centre metallique implique dans la formation d'un radical proteique, implication de ce dernier dans l'activation radicalaire du substrat, et presence d'un systeme reducteur externe fournissant les equivalents reducteurs de la reaction. Cependant, chacun des cofacteurs proteiques ou chimiques de la rnr anaerobie est original faisant de celle-ci une enzyme unique. Outre son importance biologique, la rnr anaerobie est interessante au niveau de l'evolution puisqu'elle pourrait permettre de comprendre comment les differentes rnrs se sont adaptees pour catalyser la meme reaction enzymatique.
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Campayne, Paul Anthony. "The impact of multinational banks on the international location of banking activity and the global hierarchy of financial centres". Thesis, University of Reading, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.257200.
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Monckton, Linda. "Late Gothic architecture in South West England : four major centres of building activity at Wells, Bristol, Sherbourne and Bath". Thesis, University of Warwick, 1999. http://wrap.warwick.ac.uk/34754/.
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By 1360 the Perpendicular style was established as the successor to Decorated architecture. During the subsequent one hundred and eighty years, until the Reformation, major building work was carried out at four great churches in the south west of England. The complete reconstructions of St Mary Redcliffe, Sherborne Abbey and Bath Abbey, and considerable work to the precinct at Wells Cathedral during this period, form the basis for this thesis. Through a study of each of these major centres, the issues of workshop identity and stylistic trendsetters are considered. It is shown how the interpretation of documentary evidence has impeded an understanding of these buildings, which can be revealed by an analysis of the fabric. Based primarily on a methodology of buildings archaeology and assessment of moulding profiles, traditional assumptions concerning the chronology and patronage are challenged. The new chronology for works at Sherborne Abbey, and the redating of the commencement of Bath Abbey further our understanding of the nature of masons' workshops, patronage and stylistic development within a regional context. Introspection in masons' workshops during the 15th century, and retrospection in later design in the region, demonstrates a reliance on the innovations of the 14th century, and the significance of the parish church tradition in the region, respectively. The thesis concludes with a discussion on the influence of major church workshops on domestic architecture, and the impact of the dissemination of the lodges in the early 16th century.
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Becker, Veit, Volker Heeschen, Katrin Schuh, Heinke Schieb i Tjalf Ziemssen. "Patient satisfaction and healthcare services in specialized multiple sclerosis centres in Germany". Sage, 2018. https://tud.qucosa.de/id/qucosa%3A35542.
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Background: As patients with multiple sclerosis (MS) require lifelong treatment, optimization of therapy with respect to efficacy and safety is needed to limit long-term disease progression. Patients with MS also need a range of health-related services. Satisfaction with these as well as treatment is clinically relevant because satisfied patients are more likely to adhere to therapy. The aim of this study was to determine the status of patient satisfaction and of healthcare services in 70 specialized MS centres in Germany.
Methods: In 2011, patients with MS responded to a questionnaire, which solicited clinical and demographic information, as well as patients’ perceptions of their overall situation and their satisfaction with treatment.
Results: Of 2791 patients surveyed, 81.9% had relapsing-remitting MS with mild disability [mean (standard deviation) Expanded Disability Status Scale score: 2.6 (1.8)]. Disease activity data were collected from 2205 patients, of whom 57.6% had remained relapse-free during the preceding 12 months. However, 38.9% had experienced one or more relapses, most of whom (67.3%) while receiving immunomodulatory treatment. About one-third of the patients indicated that they were more dissatisfied with their overall situation compared with the time before diagnosis. However, many patients (58.3%) were satisfied with their existing medication. Overall, 72.8% of patients would prefer oral to injectable treatments, assuming there was no difference in their efficacy.
Conclusions: A substantial proportion of patients experienced breakthrough disease on treatment and may potentially benefit from a change of therapy. Although largely satisfied with treatment, most patients with MS would choose oral over injectable treatments.
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Janne, Odile E. M. "The changing geographical spread of corporate technological activity in Europe : the dynamics of corporate technological strategies and the hierarchy of innovative centres". Thesis, University of Reading, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343345.
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Pinter, Piermaria, Andrea Biffis, Cristina Tubaro, Mario Tenne, Maria Kaliner i Thomas Strassner. "Palladium(II) complexes with electron-poor, 4,5-disubstituted diimidazol-2-ylidene ligands: synthesis, characterization and catalytic activity". Royal Society of Chemistry, 2015. https://tud.qucosa.de/id/qucosa%3A36120.
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Diimidazolium salts featuring different bridges between the imidazolium groups, as well as electron-withdrawing groups (chloride, cyanide) at the 4- and 5-position of the heterocyclic rings, have been successfully prepared. The diimidazolium salts serve as convenient precursors of di(N-heterocyclic carbene) ligands, which coordinate in a chelating fashion to palladium(II) centres. The effect of the newly introduced electron-withdrawing groups on the spectroscopic and structural characteristics of the resulting complexes as well as on their reactivity as catalysts in a model alkyne hydroarylation reaction has been investigated and is discussed herein.
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Dazdarevic, Nina, i Alexandra Stünkel. "Brukarens individuella behov eller systemets behov? : en kvalitativ studie om hur personal på daglig verksamhet arbetar med brukarens individuella behov". Thesis, Ersta Sköndal Bräcke högskola, Institutionen för socialvetenskap, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:esh:diva-8283.
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Enligt lagen om stöd och service till vissa funktionshindrade (LSS) har de som tillhör personkrets 1 eller 2 rätt till insatsen daglig verksamhet. Av samtliga tio insatser enligt LSS är daglig verksamhet vanligast. De övergripande målen med daglig verksamhet är meningsfull sysselsättning, delaktighet i samhället, stärka individens självbestämmande och att brukaren ska tillförsäkras goda levnadsvillkor. Trots stora framsteg i funktionshinderpolitiken visar forskning att dessa mål kan vara svåra att uppfylla och att dessa människor ännu marginaliseras. Syftet med denna studie är att förstå och öka kunskapen om hur personal inom daglig verksamhet arbetar för att möta brukares individuella behov. Studien är baserad på åtta kvalitativa semistrukturerade intervjuer med personal på åtta olika dagliga verksamheter i Stockholms stad. För att analysera resultatet utgick vi från teori om empowerment och paternalism. Vi identifierade tre huvudteman under kodningen; Lära känna brukaren, Genomförandeplan och Vems behov styr som presentationen av resultatet sorterats efter. Resultatet visade att daglig verksamhet är ett forum där personer med intellektuell funktionsnedsättning har möjlighet kan få sina individuella behov tillgodosedda om rätt förutsättningar ges. Vi identifierade att personal stöter på hinder för att kunna tillgodose brukarens individuella behov som vanligtvis är av organisatorisk karaktär. Det är felaktiga nivåbedömningar, brist på ekonomiska resurser, handledning och vidareutbildning samt lokaler som inte var anpassade för brukarna. Vidare fann vi att det finns stora utmaningar med att kommunicera med personer som har kognitiva svårigheter varför det är av vikt att personal har tillgång till olika kommunikativa hjälpmedel samt kunskap för att använda dessa. För att kartlägga individuella behov använder personal olika verktyg men den huvudsakliga och centrala som vi fann var genomförandeplanen. I denna studie kommer vi beskriva närmare om personalens arbetssätt, möjligheter och dess utmaningar för att möta individuella behov som visat sig vara mycket komplext.According to the Swedish act concerning support and service for people with certain functional impairment (LSS) those who meet the criteria 1 or 2 specified by the act have the right to daily activity centres. Of all ten initiatives according to LSS, daily activity centres are most common. The overall goals of daily activity centres are meaningful activities, community participation, strengthening the individual's self-determination and ensuring that the user is guaranteed good living conditions. Despite major advances in disability policy, research shows that these goals can be difficult to achieve and that these people are still marginalized. The purpose of this study is to understand and increase the knowledge of how staff in daily activity centres work to meet users' individual needs. The study is based on eight qualitative semi-structured interviews with staff at eight daily activity centres in Stockholm. We used the theory of empowerment and paternalism to analyse our results. We identified three main themes during coding; Get to know the user, Implementation plan and Whose needs is in control? by which the presentation of the results is sorted. The result showed that daily activity centres is a forum where people with intellectual disabilities have the opportunity to get their individual needs met if given the right conditions. We identified that staff encounter barriers to being able to meet the user's individual needs, which are usually of an organizational nature. There are incorrect level assessments, a lack of financial resources, guidance and further education as well as facilities that were not adapted for the users. Furthermore, we found that there are major challenges in communicating with people who have cognitive difficulties, which is why it is important that staff have access to various communication aids and knowledge to use them. To identify individual needs, staff use different tools, but the main and central one we found was the implementation plan. In this study, we will describe in more detail about the staff's way of working, opportunities and its challenges in meeting individual needs that have proved very complex.
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Dumas, Françoise. "Approches stéréoselectives d'antibiotiques de type carbapénème, thiénamycine et dérivés : contrôle relatif des centres asymétriques, construction du squelette bicyclique". Paris 6, 1987. http://www.theses.fr/1987PA066686.
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Morris, Stephanie Laura. "Understanding the place and meaning of physical activity in the lives of young people : an ethnographic study with two youth centres in a low-income urban area of Northern England". Thesis, Durham University, 2017. http://etheses.dur.ac.uk/12269/.
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This study was conducted in response to the low levels of physical activity in young people in the UK (and elsewhere) that are considered a major public health challenge. Adopting a critical ethnographic approach, this study explores how physical activity fits into the daily lives of young people (13-21-year-olds) from two youth centres in an urban area of Northern England. This approach enabled the exploration of young people’s physical activity perceptions and practices within the context, complexities, and contingencies of their wider lives, rather than as a compartmentalised phenomenon. Drawing on recent re-conceptualisations of the life-course and anthropological theories of childhood, I show that changes in physical activity over time were enmeshed within life-phase expectations and experiences, but were also non-linear and contingent. Social expectations of adolescence limited some young people’s physical activity practices, and yet many etched out ways of being mobile and physically active, including re-living childhood games on the streets, parks, and at youth centres. Employing spatial theories, I explain how the young people negotiated their sense of safety in their local environments in order to be mobile; created places of their own for sociality; and used spaces and props in the material environment to engage in informal physical activity practices such as “hardcore parkour”. I lastly use Foucauldian and gender theories to re-think how understandings and practices of physical activity were gendered, and centred around the self and the body’s appearance and capability. Many of the young men in particular engaged in ‘self-bettering’ practices: some took up boxing to deal with challenges in their lives and some shaped muscular, fit, and ‘healthy’ bodies. This thesis critically challenges the dominant discourses that shape young people’s individualistic understandings of themselves, their lives, and their physical activity practices. Engaging closely with the young people’s actions and experiences helps to reveal how the socioeconomic and material environments, that young people negotiate in daily life, interact with their physical activity and mobility practices.
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Boadas, Mir Elena. "L'aportació de les activitats dels centres de ciència al desenvolupament de la competència científica en l'alumnat d'educació primària. El cas de la fundació CRAM". Doctoral thesis, Universitat Autònoma de Barcelona, 2020. http://hdl.handle.net/10803/669640.
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Aquesta tesi doctoral analitza la repercussió d’una activitat educativa d’un centre de ciència, la Fundació CRAM, en el desenvolupament de les dimensions de la competència científica (conceptual, actitudinal i d’actuació), en alumnes de cicle superior de primària; i, identifica els elements de l’activitat que influeixen en la millora d’aquest desenvolupament, sobretot en relació a la dimensió d’actuació.
Per a l’estudi s’han analitzat diversos grups escolars que han participat en l’activitat educativa al llarg de dos cursos consecutius, aplicant una metodologia interpretativa, des de les vessants quantitativa i qualitativa.
La recerca s’ha estructurat en tres fases. En primer lloc (fase I), s’analitza quina és la incidència de l’activitat en el desenvolupament de les tres dimensions de la competència científica estudiades, que permet evidenciar la influència de l’activitat en cadascuna de les tres dimensions. En segon lloc (fase II), s’analitza la tipologia d’arguments, que utilitzen els alumnes després de l’activitat, per donar resposta a una problemàtica ambiental, que permet constatar la significativitat i funcionalitat dels aprenentatges derivats de l’activitat i, la seva contribució en el canvi de visió que construeix l’alumnat davant d’una problemàtica ambiental.
I, en tercer lloc (fase III), s’analitzen els elements de l’activitat que han afavorit aquest desenvolupament, aplicant el model d’anàlisi de la Teoria de l’Activitat d’Engeström.
Aquesta darrera anàlisi ha ajudat a identificar els elements didàctics de l’activitat que tenen una repercussió favorable en el desenvolupament de les tres dimensions de la competència científica estudiades; i, a evidenciar la importància d’un treball compartit entre els centres educatius i els centres de ciència.
En resum, la investigació que es realitza en aquesta tesi ha permès aprofundir sobre la funció educativa dels centres de ciència i la seva aportació en el desenvolupament de les dimensions (conceptual, actitudinal i d’actuació) de la competència científica; i, aporta evidències i reflexions per replantejar i millorar el disseny de les activitats educatives en aquests centres d’educació no formal.This doctoral thesis analyzes the impact of an educational activity of a science center, the CRAM Foundation, on the development of the dimensions of the scientific competence (conceptual understanding, attitude and performance), in students of upper elementary school; and it identifies specific elements of the activity which help improve this development, especially in relation to the perfomance dimension. The study analyzes several groups of students that have participated in the educational activity during two consecutive courses. The methodological approach is interpretative, including both quantitative and qualitative perspectives. The research has been structured in three phases. In the first place (Phase I), the effect of the activity on the development of the three dimensions of the scientific competence is analyzed, which allows to show the influence of the activity on each one of the three dimensions. In the second place (Phase II), the type of arguments used by the students after the activity is analyzed. These arguments are used in order to answer to an environmental problem, which allows to verify the significance and functionality of the learning derived from the activity and its contribution to the change of students’ mindset in front of an environmental problem. And, in the third place (phase III), the elements of the activity that have favored this development are analyzed applying Engeström’s Activity Theory. This analysis has helped identify the didactic elements of the activity that have a favorable impact on the development of the three dimensions of the scientific competence; as well as show the importance of joint work between the educational centers and the science centers. In summary, the research carried out in this thesis has allowed to further describe the educational function of science centers and their contribution to the development of the dimensions (conceptual understanding, attitude and performance) of scientific competence; and it provides evidence and reflections to rethink and improve the design of educational activities in these non-formal education centers.
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Le, Louët Guillaume. "Maîtrise énergétique des centres de données virtualisés : D'un scénario de charge à l'optimisation du placement des calculs". Phd thesis, Ecole des Mines de Nantes, 2014. http://tel.archives-ouvertes.fr/tel-01044650.
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Cette thèse se place dans le contexte de l'hébergement de services informatiques virtualisés et apporte deux contributions. Elle propose premièrement un système d'aide à la gestion modulaire, déplaçant les machines virtuelles du centre pour le maintenir dans un état satisfaisant. Ce système permet en particulier d'intégrer la notion de consommation électrique des serveurs ainsi que des règles propres à cette consommation. Sa modularité permet de plus l'adaptation de ses composants à des problèmes de grande taille. Cette thèse propose de plus un outil pour comparer différents gestionnaires de centres virtualisés. Cet outil injecte un scénario de montée en charge reproductible dans une infrastructure virtualisée. L'injection d'un tel scénario permet d'évaluer les performances du système de gestion du centre grâce à des sondes spécifiques. Le langage utilisé pour cette injection est extensible et permet l'utilisation de scénarios paramétrés.
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Roche, Béatrice. "Etude du rôle de la frataxine bactérienne CyaY chez Escherichia coli". Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM4083.
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Les protéines à centre Fe-S sont impliquées dans de nombreux processus cellulaires. In vivo, la formation des centres Fe-S est réalisée par des machineries multi-protéiques dont ISC et SUF, conservées chez les eucaryotes et les procaryotes. D’autres composants participent à la formation des centres Fe-S chez les eucaryotes, comme la frataxine (FXN). La FXN est une protéine présente chez l’homme, les plantes, la levure ou encore les bactéries à Gram négatif. Chez les eucaryotes, l’absence de FXN conduit à des phénotypes drastiques comme une accumulation de fer dans la mitochondrie, une diminution drastique de l’activité d’enzymes à centre Fe-S ou encore des dommages oxydatifs. Chez l’homme, un déficit en FXN est responsable d’une maladie neurodégénérative, l’ataxie de Friedreich. A la différence des eucaryotes, chez les procaryotes comme Escherichia coli, l’absence de CyaY, homologue bactérien de la FXN, ne conduit à aucun des phénotypes évoqués ci-dessus.Durant ma thèse, je me suis intéressée au rôle de CyaY chez E. coli. J’ai montré que, in vivo, CyaY favorise la formation des centres Fe-S via la machinerie ISC. Un lien génétique entre CyaY et IscX a également pu être établi, montrant que ces deux protéines participent à la formation des centres Fe-S in vivo. Je me suis ensuite intéressée aux bases moléculaires pouvant expliquer la différence entre les phénotypes liés à l’absence de FXN chez les eucaryotes et les procaryotes. J’ai montré que le résidu 108 de IscU joue un rôle clé pour la dépendance de CyaY. Enfin, pour mieux comprendre le rôle de CyaY chez E. coli, j’ai réalisé une approche globale en caractérisant le transcriptome du mutant ∆cyaYFe-S cluster containing proteins are involved in many cellular processes such as respiration, DNA repair or gene regulation. In vivo, Fe-S cluster biogenesis is catalysed by specific protein machineries, ISC and SUF, conserved in both eukaryotes and prokaryotes. Frataxin (FXN) is a small protein found in humans, plants, yeast and Gram negative bacteria. In eukaryotes, a defect in FXN leads to drastic phenotypes such as mitochondrial iron accumulation, drastic decrease of Fe-S cluster protein activity, sensitivity to oxidants. In humans, FXN deficiency is responsible for the neurodegenerative disease, Friedreich’s ataxia. In prokaryotes like E. coli, a defect in CyaY, the bacterial FXN homolog, does not lead to significant phenotypes compared to the wild-type strain. During my thesis, I investigated the role of the bacterial FXN CyaY in E. coli. I showed that, in vivo, CyaY assisted the ISC-catalyzed Fe-S cluster biogenesis. A genetic link was also observed between cyaY and iscX, demonstrating that these proteins participate in Fe-S cluster biogenesis. In a second part, I investigated the differences between the impact of the eukaryotic versus prokaryotic FXN. I showed that the IscU 108th residue is crucial for the CyaY-dependency. Finally, I used a transcriptomic approach to test whether CyaY has a global role in E. coli
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Juntunen, A. L. (Anne-Leena). "Uusia työtapoja päiväkotityöhön:tutkimus sosionomi (AMK) -koulutuksen asiakastyön harjoittelusta". Doctoral thesis, Oulun yliopisto, 2010. http://urn.fi/urn:isbn:9789514263828.
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Abstract The development of new work practices requires the combination of several organizations. The interaction and knowledge formation of the participants are the essential factors. The aim of this study was to reveal their potential for forming new work practices to day-care centre work in the practice of Social Services (UAS) studies. The research focused on co-operative learning of the network of persons representing universities (academic and applied sciences) and day-care centres. The methodology of the study is based on developmental work research. Four different types of data were collected: 1. Discussion data of the Social Services (UAS) students, teachers and work place instructors during joint planning sessions, 2. Their stimulated recall -interview data, 3. The historical analysis of the day-care work, 4. Historical analysis of the transfer concept. The “expansive learning cycle” and historical analysis of the transfer were used as conceptual tools of analyzing teamwork and knowledge formation of the teams. The activity system model of developmental work research was used as conceptual tool of analyzing learning of the teams. Central themes were further elaborated using stimulated recall – interviews. The interaction mainly consisted of presenting one’s own view, and on the other hand, solving a common problem. The team did not question the interaction at a personal level. The team was not able to construct the common activity system and the boundary object between different institutions (the university, university of applied sciences and the day-care centres). Knowledge formation was conducted by reconstruction of existing knowledge and traditional transfer. On the other hand, regenerative learning and knowledge formation were developed in the activity system of the day-care centre and education. The team observed children’s learning and the contradictions of current activity and formed a new theoretical concept. It was applied as a tool for the activity of students. The new insight was not expanded to the work in day-care centres. Mere conversation is not sufficient - new work practices require mutual trust, strong network connections and the ability to assess and develop the attitude towards a more co-operative one. Knowledge formation provides regenerative learning. What is essential is questioning present practices, knowing the zone of proximal development of the work and modeling of new ideas. The most important in knowledge formation, interaction and learning are the theories of learning. The starting point to develop the work is to find the right object based on the needs of working lifeTiivistelmä Uusien työtapojen kehittäminen vaatii useiden organisaatioiden yhteistoimintaa. Keskeistä on eri asiantuntijoiden vuorovaikutus ja tiedonmuodostus. Tutkimuksessa selvitettiin kehittäjätiimin vuorovaikutuksen ja tiedonmuodostuksen suhdetta uusien työtapojen muodostumiseen sosionomi (AMK) -koulutuksen harjoittelussa. Tutkimus kohdistui yliopiston, ammattikorkeakoulun ja päiväkodin edustajien yhteistoiminnalliseen oppimiseen tavoitteenaan kehittävä siirtovaikutus. Tutkimuksen metodologia perustuu kehittävään työntutkimukseen. Tutkimus sisältää neljä aineistoa: 1. Sosionomi (AMK) -opiskelijoiden, opettajien ja työpaikkaohjaajien keskusteluaineiston, 2. stimulated recall -haastatteluaineiston, 3. päiväkotityön historiallisen kehityksen analyysiaineiston, 4. siirtovaikutuksen käsitteen historiallisen analyysiaineiston. Keskusteluaineiston vuorovaikutuksen analyysimenetelmänä käytettiin tiimityön analysoinnin käsitteellisiä välineitä. Tiedonmuodostusta analysoitiin ekspansiivisella oppimissyklillä ja siirtovaikutuksen kehitysvaihemallilla. Päiväkotityön historia-analyysiä käytettiin osallistujien kehittämiskohteen tulkintaan. Oppimista analysoitiin toimintajärjestelmän rakennemallilla. Stimulated recall -haastattelut täydensivät analyysejä. Kehittäjätiimin vuorovaikutuksessa korostui oman näkökulman esittäminen ja toisaalta yhteisen ongelman ratkaiseminen. Osallistujat eivät kyseenalaistaneet yksilötason vuorovaikutustaan. Tiimi ei pystynyt luomaan yliopiston, ammattikorkeakoulun ja päiväkodin edustajien yhteistä toimintajärjestelmää ja kehittämiskohdetta. Tiedonmuodostusta ohjasivat valmiin tiedon rekonstruointi ja staattinen siirtovaikutus. Toisaalta päiväkodin ja koulutuksen toimintajärjestelmässä kehittyi uudistavaa oppimista. Osallistujat käsittelivät lasten oppimista, nykytoiminnan ristiriitoja ja muodostivat uuden selitysmallin, jolla oli teoreettista merkitystä opiskelijan toiminnan välineenä. Uusi selitysmalli ei siirtynyt päiväkotityöhön. Pelkkä keskustelu ei riitä - uudet työtavat edellyttävät keskinäistä luottamusta, vahvoja verkostosuhteita sekä kykyä arvioida ja kehittää asennetta yhteistoiminnallisuuteen. Tärkeimmiksi tiedonmuodostusta, vuorovaikutusta ja oppimista sääteleviksi tekijöiksi nousevat oppimisteoriat. Uudistukset edellyttävät uudistavaa oppimista. Keskeistä on taito yhdessä kyseenalaistaa nykyistä toimintaa, hahmottaa työn lähikehitys sekä mallittaa uusia ideoita. Lähtökohtana ovat työelämän tarpeista nousevat kehittämiskohteet
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Lee, Kwok-cheung Andy. "An urban activity focus for the youth". Hong Kong : University of Hong Kong, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B25950745.
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Yao, Koffi Jean-Marie. "Compétitivité et attractivité des places financières internationales : application à l'industrie des fonds d'investissement au Luxembourg". Phd thesis, Université de Strasbourg, 2012. http://tel.archives-ouvertes.fr/tel-00842878.
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La majeure partie des études sur les centres financiers concerne le domaine bancaire. Les autres secteurs de la finance semblent avoir été délaissés. Cette thèse a pour objet de décrire la compétitivité et l'attractivité des centres financiers en matière de fonds d'investissement. Au travers d'une revue de littérature sur la compétitivité et à l'attractivité dans les centres financiers, nous identifions les stratégies pour l'émergence des places. Nous avons ainsi défini plusieurs déterminants d'attractivité et de compétitivité appliquées au centre financiers par une analyse critique des différents indicateurs d'évaluation de ces concepts. Une approche théorique de l'interaction entre "centre financier", "compétitivité et attractivité", et "industrie des fonds d'investissement" nous permet d'aborder les éléments fondamentaux de l'analyse de la compétitivité et de l'attractivité dans l'industrie des fonds. Partant d'une définition de l'économie des fonds, nous étudions les relations entre l'industrie des fonds d'investissement et l'environnement immédiat (clients et Etats). Avec une enquête auprès des professionnels de la place, nous donnons les fondamentaux de l'émergence de la place luxembourgeoise. Dans une approche économétrique, nous abordons aussi l'impact de l'industrie des fonds sur les investissements directs étrangers. L'intérêt majeur de cette thèse est de confronter les résultats de modélisations théoriques et économétriques à des données d'enquête auprès des professionnels de fonds. Le choix de la population statistique est guidé par l'importance de la place financière luxembourgeoise en Europe.
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Johansson, Robin. "GOTTSUNDA DISTRICT CENTRE". Thesis, KTH, Arkitektur, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-261274.
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IN BETWEEN GOTTSUNDA SQUARE AND A NATURE AREA IS THE NEW DISTRICT CENTER INTENDED TO BE PLACED.THE PLACE IS A POSSIBILITY THAT CREATES CONDITIONS FOR A BUILDING WHICH EXPANDS PRIDE, JOY AND OPENITY. ONE OF THE AMBITIONS IS TO CREATE A VIVID BUILDING OPENING UP TO THE SQUARE, AT THE SAME TIME THAT IT RELATES AND ENHANCES THE NEARBY BUILDING. THE BUILDING ACTIVITIES AT THE ENTRY PLAN IS OPEN, AND PLAY VISUALLY FROM THE SQUARE WITH ITSOPENNESS. OUTDOORS AT THE BUILDING BODIES WITH ITS VARIETY OF CULTURE AND SPORTS ACTIVITIES WILL BE APPLIED FOR PEOPLE IN ALL AGES. THE OUTDOOR AREAS SHOULD WORK AS A PART OF THE BUILDING PROGRAM DURING OPENING TIME, SUCH AS AFTER CLOSING TIME. WITH ITS CHARACTERISTIC MATERIAL CHOICE IN WOOD, THE CONSTRUCTION CONNECTES WITH THE ENVIRONMENTAL NATURE, AND AT THE SAME TIME GIVES THE OPPORTUNITY TO BUILD IN A SUSTAINABLE MATERIAL TAKING ACCOUNT OF CLIMATE IMPACT. THE BENEFIT IN ENERGY USE, CARBON DIOXIDE EMISSIONS AND WASTE ARE IMPORTANT QUESTIONS TODAY AND FEEL IMPORTANT TO WORK WITH IN GOTTSUNDA AS A NEW WAY TO THINK IN MATERIAL AFTER A GREAT USE OF CONCRETE HOUSE FROM THE MILLION PROGRAMME.MITT EMELLAN GOTTSUNDA TORG OCH ETT VILTVUXET NATUROMRÅDE INFOGAS DET NYA STADSDELCENTRET. PLATSEN UTGÖR EN MÖJLIGHET SOM SKAPAR FÖRUTSÄTTNINGAR FÖR EN BYGGNAD SOM UTSTRÅLAR STOLTHET, GLÄDJE OCH ÖPPENHET. EN AV AMBITIONERNA ÄR ATT SKAPA EN LEVANDE BYGGNAD SOM ÖPPNAR UPP SIG MOT TORGET, SAMTIDIGT SOM DET KNYTER SAMMAN OCH FÖRSTÄRKER GATULIVET MED DEN NÄRLIGGANDE BYGGNADEN. BYGGNADENS VERKSAMHETER VID ENTRÉPLAN ÄR ÖPPNA, OCH SPILLER VISUELLT UT FRÅN TORGET MED SIN ÖPPENHET. UTOMHUSYTORNA VID BYGGNADSKROPPARNA MED SITT VARIERANDE UTBUD AV KULTUR OCH SPORTAKTIVITETER SKA VÄCKA INTRESSE FÖR FOLK I ALLA ÅLDRAR. YTORNA SKA FUNGERA SOM EN DEL UTAV BYGGNADENS PROGRAM UNDER ÖPPNINGSTID, SÅVÄL SOM STÄNGNINGSTID. MED SITT KARAKTERISTISKA MATERIALVAL I TRÄ KOPPLAR BYGGNADEN SAMMAN MED DET OMKRINGLIGGANDE NATUROMRÅDET SAMTIDIGT SOM DET GER MÖJLIGHETEN ATT BYGGA I ETT HÅLLBART MATERIAL SOM TAR HÄNSYN TILL KLIMATPÅVERKAN. FÖRDELEN VAD GÄLLER RESURSHÅLLNING, ENERGIANVÄNDNING, KOLDIOXIDUTSLÄPP OCH AVFALL ÄR VIKTIGA FRÅGOR IDAG OCH KÄNNS SJÄLVKLART ATT LYFTA FRAM I GOTTSUNDA SOM EN NY FRISK FLÄKT EFTER EN STOR ANDEL BETONGHUS FRÅN MILJONPROGRAMMET.
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Pupkevičiūtė-Kiguolė, Edita. "Dienos centro veiklos ypatumai sprendžiant vaikų, patiriančių smurtą šeimoje, problemas". Master's thesis, Lithuanian Academic Libraries Network (LABT), 2011. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20110802_164921-90082.
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Smurtas prieš vaikus šeimoje yra pasaulinė problema. Jis egzistuoja visose šalyse, kultūrose ir visuomenės sluoksniuose, nepaisant žmonių išsilavinimo ar pajamų dydžio. Smurtas prieš vaikus pasiižymi fiziniu bei psichologiniu smurtu, seksualine prievarta ir nepriežiūra. Vis aktyviau Lietuvoje kuriama socialinių paslaugų sistema, kuri dar nėra pakankamai orientuotą į efektyvią pagalbą vaikui, visapusišką jo teisių apsaugą. Svarbu sukurti saugią aplinką vaikams, patyrusiems smurtą šeimoje. Vienas iš pagalbos būdų yra vaikų dienos centrai (VDC).
Tyrimo objektas – dienos centro veikla orientuota į vaikus, patiriančius smurtą šeimoje.
Tikslas – ištirti dienos centro veiklos ypatybes, padedančias spręsti vaikų, patiriančių smurtą šeimoje, problemas.
Tyrimo metodai: mokslinės literatūros analizė, anketinė apklausa raštu, gautų duomenų kiekybinė ir kokybinė analizė.
Tyrimo imtis: apklausti 36 vaikų dienos centrų darbuotojai bei savanoriai. Vaikų, lankančių VDC imtis – 231 tyrimo dalyvis. Bendra tyrimo imtis – 267 respondentai.
Tyrimo metodologija grindžiama: Poreikių teorija (Maslow, 2006; Rogers, 2005); Humanistine asmenybės teorija (Maslow, 2006); Ugdymo filosofijos ir Hodegetikos nuostatomis apie vaiko auklėjimą, tapsmą socialine būtybe.
Svarbiausios empirinio tyrimo išvados: tyrimas parodė, kad vaikų dienos centrai vykdo smurto prevenciją, pagal galimybes stengiasi padėti smurtą šeimose patiriantiems vaikams. Tačiau ne visada įsigilinamą į vaikų poreikius, o dienos centrų... [toliau žr. visą tekstą]Violence against children in the family is a worldwide problem. It exists in all countries, cultures, levels of society regardless of people’s education and incomes. Violence against children includes physical and psychological abuse, sexual abuse and child neglect. Social services system is being developed in Lithuania more actively, but it is not sufficiently focused on effective aid to the child and the full protection of his/her rights. It is very important to create a safe environment for children who had experience family violence. Children Day Centres (CDC) is one of the ways to help a child. The subject of the research – the activity of the Day Centre oriented towards children experiencing family violence. The aim of the research: to investigate the peculiarities of the activity of the Day Centre which help to solve the problems of the children experiencing family violence. The research methods: scientific literature analysis, questionnaire survey (in written form), quantitative and qualitative analyses of the obtained data. The volume of the research: 36 employees of the Day Centre and volunteers were interviewed. The volume of the children attending CDC is 231 participants. Total volume of the research is 267 respondents. The grounding of the research methodology: Hierarchy of needs (Maslow, 2006; Rogers, 2005); Humanistic theory (Maslow, 2006); the provisions of Philosophy of Education and Hodegetics on the child's upbringing and social transition to being. The... [to full text]
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Lee, Kwok-cheung Andy, i 李國祥. "An urban activity focus for the youth". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31984666.
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Kirk, Philip J. "Passenger experience at airports : An activity-centred approach". Thesis, Queensland University of Technology, 2013. https://eprints.qut.edu.au/60803/8/Philip_Kirk_Thesis_Signature%20Redacted.pdf.
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This project has provided a new understanding of the passenger experience in Australian international airport departure terminals. A novel understanding of the passenger experience developed by observing the activities passengers carried out on their day of travel, and interviewing passengers and staff members. The development of the Taxonomy of Passenger Activities (TOPA) has been an important outcome of this research. It provides a new understanding of the airport passenger experience at departure. The Taxonomy of Passenger Activities identifies the activities that improve the experience of passengers and the processing efficiency of the airport terminal.
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Nouel, Dominique. "Etudes fonctionnelle et neurobiologique des transmissions neurotensinergiques centrales. Relation avec les systèmes dopaminergiques". Rouen, 1992. http://www.theses.fr/1992ROUES046.
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Nous avons étudié l'influence de la dégradation de la neurotensine (NT) et de la neuromedine N (NN) sur l'hypothermie et l'activité locomotrice résultant de leur injection intracérébroventriculaire (i. C. V. ). L'administration de NT en présence d'inhibiteurs de l'endopeptidase 24. 11, tout comme celle de [DTrp 11]NT induit chez le rat une hypokinésie à faible dose (15-250 ng) et une hyperkinésie à forte dose (>750 ng). L'injection de NN, en présence de bestatine et de thiorphan (inhibiteurs respectivement de l'aminipeptidase et de l'endopeptidase 24. 11) reproduit l'hypothermie et l'augmentation d'activité motrice induite par la NT. Dans un second temps nous avons étudié les relations fonctionnelles pouvant exister entre la NT et les transmissions dopaminergiques. La NT augmente le délai de dépassement du seuil en réponse à un stimulus acoustique. La NT inhibe les bâillements induits par l'administration d'apomorphine et de pilocarpine. L'existence d'une complexation mutuelle de la NT et de la dopamine n'a pas été confirmée. Le halopéridol bloque l'augmentation d'activité motrice induite par la [DTrp 11]NT. Cette augmentation est potentialisée par le GBR 12783. Elle n'est plus observée 4 jours après la destruction des terminaisons catécholaminergiques du noyau accumbens par l'hydroxy-6-dopamine. On a observé une récupération partielle de l'effet stimulant de la locomotion 15 jours après cette lésion, alors même que l 'innervation dopaminergique du noyau accumbens n'était pas rétablie
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Nusshold, Patricio. "Organisation du travail et souffrance psychique dans les activités de service : le cas des centres d'appel en Argentine". Thesis, Paris, CNAM, 2015. http://www.theses.fr/2015CNAM1023/document.
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Cette recherche est le résultat de deux travaux d’analyse de l’activité dans deux centres d’appels téléphoniques en Argentine. Un travail de terrain, ainsi qu'une appréciation de plusieurs autres centres d’appels téléphoniques dans différents pays, auront servi de point de départ pour étudier deux grands axes: d’une part, l’étude des conséquences du travail dans les call centers sur la santé mentale et d’autre part, l'analyse des différentes approches de cette problématique en vue de sa transformation. La psychodynamique du travail et l’ergonomie de l’activité proposent différents regards, aujourd’hui confrontés aux questionnaires d’évaluation des risques psychosociaux. Cette thèse vise à mieux appréhender le lien entre l’organisation du travail, le contenu des tâches et les conséquences pour les travailleurs argentins, et compare ces résultats avec ceux d' autres pays où des investigations similaires ont été menéesThis research is the result of a thorough analysis of the work of two call centers in Argentina. This fieldwork, building on call center visits undertaken in other countries, is the starting point for the study of two main issues. Firstly, the study of the consequences of call center work for mental health. Secondly, the study of different approaches that support the development of ways to improve it such work. Work psychodynamics and activity ergonomics are two disciplines that propose different points of view on these issues. Nowadays, they both find themselves confronted by quantitative scales that seek to measure psychosocial risks. The aim of this thesis is to increase knowledge on the relationship between work organization and tasks content and highlight the consequences for workers in Argentina. The thesis shall also compare results of the study with those found in other countries
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Wilkinson, D. R. "Repeated igneous activity through continental lithosphere, central Portugal". Thesis, University of Reading, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356494.
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Timucin, Metin. "Teaching literature in a Turkish EFL context : empirical exploration of activity-based and process-oriented approaches". Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.325685.
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Zhao, Yu. "Identification and classification of activity centers based on passenger flows data". Thesis, KTH, Transport- och lokaliseringsanalys, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-149467.
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In the past decades, the spatial structure of metropolitan areas has progressively changed towards a more polycentric structure. Many researchers have studied this polycentric structure in the context of North American and European metropolitans by identifying sub-centers, mainly using two methods which are analyzing the employment or population density or mobility data. In spite of huge effort in identifying sub-centers, fewer studies characterize the identified sub-centers and classify them based on their patterns and features simultaneously. And this research will identify sub-centers and then classify them as well. Following the introduction of polycentricity and a review of previous methodologies for identification and classification of sub-centers, this study introduces two different algorithms: flow-based and distance-based for identifying sub-centers based on passenger flows data at public transport stations. In addition, the study presents the classification process of identified clusters based on time-dependent passenger flows data. Temporal profiles of each cluster are created and used to describe their characteristics, and then classification is conducted based on hierarchical clustering analysis. As a case study, the emergence of polycentric structure in Stockholm County is analyzed using public transport passenger flows at each station including metros, commuter trains, buses and light rails. After comparing results of the two proposed algorithms, the distance-based is chosen for Stockholm case. The identification algorithm yields 17 clusters. These 17 clusters are then classified using three different indicators based on flow data by time intervals. As a result, we have three classification results. Finally, the classification results are analyzed and synthesized by considering the urban environment of clusters and their roles in transport network, providing a comprehensive interpretation of resulted clusters. Clusters are classified into seven more general classes of center, business, residential, hub or combinations of them. The result suggests that each cluster is associated with distinctive functions and they are all active, unlike ‘’sleeping towns’’, however, clusters in the inner city are still able to generate and attract more flows and flows are still more concentrated in the central part, indicating the aim to release pressure from central part by polycentric structure hasn’t been fully achieved yet.
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Muthersbaugh, Michael S. "Seasonal activity patterns of bats in the Central Appalachians". Thesis, Virginia Tech, 2018. http://hdl.handle.net/10919/93761.
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Two threats to bats are especially pervasive in the central Appalachian Mountains of the eastern United States: a fungal disease called White-nose Syndrome (WNS) and wind energy development. White-nose Syndrome has caused the death of millions of bats in North America, and multiple hibernating bat species are affected in the central Appalachians. Wind energy is one of the most rapidly-growing energy sources in eastern United States, and bats are often killed when they fly near wind turbines. Fatality rates at wind turbines is highest in bat species that migrate instead of hibernate. There is limited data on bats during the autumn and spring seasons in the central Appalachian Mountains, and the impacts of WNS and wind energy development may be exacerbated during these seasons. Therefore, I sought to determine patterns and drivers of activity for hibernating bat species during autumn and spring around hibernacula. Similarly, I set out to determine patterns and drivers of activity for migratory bat species during autumn and spring along mountain ridgelines in the central Appalachians. Lastly, I searched for evidence of potential WNS-induced changes in the summer ecology of the once common northern long eared bat. This study can help elucidate patterns of bat activity during largely understudied seasons. Furthermore, it can provide useful information needed by land managers to implement actions that could help alleviate and/or avoid potential additive negative impacts on bat species with existing conservation concerns.MS
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Ward, Stephanie Ann. "Association entre l’environnement social en milieu de garde et les comportements liés à l’apport alimentaire et l'activité physique des enfants de trois à cinq ans". Thèse, Université de Sherbrooke, 2016. http://hdl.handle.net/11143/9740.
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Résumé : Problématique : Puisque les enfants de moins de cinq ans passent environ 29 heures par semaine dans les milieux de garde et qu’ils apprennent en observant et en imitant les autres, les éducateurs et les pairs peuvent être des modèles importants dans l’apprentissage de saines habitudes de vie. Les objectifs étaient d’analyser les associations entre 1) les pratiques des éducateurs et l’apport alimentaire, 2) l’activité physique (AP) des enfants de trois à cinq ans dans les milieux de garde, 3) le degré d’influence des pairs sur l’apport alimentaire, et 4) l’AP des enfants de trois à cinq ans.
Méthodes : Les associations entre les pratiques des éducateurs et les comportements liés à l’apport alimentaire et l’AP des enfants ont été étudiées à l’aide d’une étude transversale, menée auprès de 723 enfants de trois à cinq ans de 51 milieux de garde en Saskatchewan et au Nouveau-Brunswick à l’automne 2013 et 2014. Le degré d’influence des pairs sur l’apport alimentaire et l’AP des enfants a été étudié à l’aide d’une étude longitudinale, menée auprès de 238 enfants de trois à cinq ans au début et à la fin des années scolaires 2013-2014 et 2014-2015. L’AP des enfants a été mesurée à l’aide d’accéléromètres, et l’apport alimentaire a été mesuré à l’aide d’une analyse de consommation par pesée et photographiée. Une grille d’observation de l’environnement a permis de mesurer les pratiques des éducateurs en milieu de garde. Des régressions linéaires multiniveaux ont répondu aux quatre objectifs de l’étude.
Résultats : Le modelage est positivement associé à l’apport en sucre (p=0,026) et l’éducation alimentaire est négativement associée à l’apport en calories (p=0,026) et en fibres (p=0,044). Ne pas utiliser de récompenses alimentaires est négativement associée à l’apport en gras (p=0,049). Aucune pratique n’est associée à l’AP des enfants. Plus l’écart entre l’apport alimentaire et l’AP des enfants et ceux de leurs pairs est grand au début de l’année, plus les enfants voient leur apport alimentaire et leur AP changer, se rapprochant de la moyenne de leurs pairs neuf mois plus tard (p<0,05).
Conclusion : Les éducateurs et les pairs jouent un rôle important dans l’adoption d’habitudes alimentaires saines et d’AP chez les enfants de trois à cinq ans dans les milieux de garde. L’environnement social est donc important à considérer dans les interventions de promotion d’habitudes de vie saine dans les milieux de garde.Abstract : Background: Since children under the age of 5 spend approximately 29 hours per week in childcare centres and that they learn by observing and imitating others, childcare educators and peers can be important role models in promoting a healthy lifestyle. The objectives were to analyse the associations between 1) educators’ practices and the dietary intake, 2) physical activity (PA) of 3 to 5 year-old children in childcare centres, 3) peers’ behaviours, and children’s dietary intake, and 4) PA of three- to five-year-old children. Methods: Associations between childcare educator practices, and children’s dietary intake and PA were analysed by a cross-sectional study conducted among 723 three- to five-yearold children from 51 childcare centres in Saskatchewan and New Brunswick in the fall of 2013 and 2014. The associations between peers’ behaviours, and children’s dietary intake and PA were studied using a longitudinal design, conducted among 238 three- to five-yearold children at the beginning and at the end of the 2013-2014 and 2014-2015 school years. Children’s PA was assessed using accelerometers, and dietary intake was measured using weighed plate waste method and digital photography. An environmental observation checklist was used to measure educators’ practices within the childcare centre. Multilevel linear regressions were used to answer all four of the study’s objectives. Results: Modeling is positively associated with children’s intake in sugar (p=0.026) and nutrition education is negatively associated with children’s intake in calories (p=0.026) and in fibre (p=0.044). Not using food rewards is negatively associated with children’s intake in fat (p=0.049). None of the practices are associated with children’s PA. The greater the difference between children’s intake or PA and those of their peers at the beginning of the year, the more likely they are to change their intakes and PA to become more similar to their peers 10 months later (p<0.05). Conclusions: Educators and peers can play an important role in the adoption of healthy eating behaviours and PA of three- to five-year-old children in childcare centres. The social environment is therefore important to consider in interventions which aim to promote healthy lifestyles in childcare centres.
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Glover, Nichole Leigh. "Factors That Influence Physical Activity Among African American Mothers at Recreation Centers". ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/6832.
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Physical activity is a critical factor in preventing obesity and other chronic illnesses. African American women experience higher rates of physical inactivity than the general population. As a key figure in the family, African American mothers should model healthy behaviors to the family, especially their children. This qualitative study explored the physical activity attitudes of African American mothers who frequently visit a recreation center in the Columbus, Ohio, area. The research questions focused on the possible barriers and motivators for physical activity engagement. The theory of planned behavior, which emphasizes behaviors, intentions, and attitudes when exploring health behaviors, guided the study. Purposeful sampling was applied to recruit a sample of 17 African American mothers over the age of 18 from 5 recreation centers. Participants who met inclusion criteria participated in a semi-structured one-on-one interview. Data were analyzed by hand coding and NVivo to capture and analyze themes, including (a) physical movement, (b) physical health, (c) environment, (d) schedule, (e) physical appearance, and (f) well-being. The findings indicated that African American mothers are aware of the value of physical activity for themselves and their families. However, personal responsibilities may prevent them from engaging in regular physical activity. The study contributes to social change by providing community center directors and public health professionals with information that they can use to create more culturally sensitive physical activity interventions.
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Van, der Merwe E. L. (Elizabeth Louisa). "Network : depolarize the city - a media centre". Diss., University of Pretoria, 2008. http://hdl.handle.net/2263/26920.
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The project is aimed at the depolarization of the polar community of the Metropolitian of Tshwane. This is done through creating a network by means of a media centre. This project is also to adress the transition phase, between formal and informal activity. The full text of this thesis/dissertation is not available online due to errors in the script . Please contact us if you need access.Dissertation (MArch(Prof))--University of Pretoria, 2008.
Architecture
unrestricted
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Kiive, Evelyn. "Studies on peripheral markers of central serotonergic activity and behaviour /". Tartu : Tartu University Press, 2005. http://dspace.utlib.ee/dspace/bitstream/10062/1064/5/kiive.pdf.
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McGuire, Michelle. "NON-PARTICIPATORS’ PERCEPTIONS OF THE BENEFITS AND BARRIERS TO TAKING PART IN FITNESS CLASSES AT SENIOR CENTERS". Miami University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=miami1493322921375054.
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Shaw, BS, I. Shaw i GA Brown. "Effects of resistance training on total, central and abdominal adiposity". South African Journal for Research in Sport, Physical Education and Recreation, 2009. http://encore.tut.ac.za/iii/cpro/DigitalItemViewPage.external?sp=1001733.
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Abstract
Despite the clear benefits that resistance training might have in weight management
the effects of resistance training on adiposity in sedentary individuals are
unsubstantiated. As such, the aim of the study was to determine the effect of
resistance training on anthropometric measures of total, central and abdominal
adiposity. Twenty-five healthy, sedentary males not on an energy-restricted diet were
assigned to a non-exercising control group (CON) (n = 12) or a resistance training
group (RES) (n = 13) to determine the effect of 16 weeks of resistance training on
anthropometric measures of total, centrally located and abdominal adiposity.
Resistance training was prescribed three times weekly using eight exercises for three
sets of 15 repetitions at 60% of one-repetition maximum. Resistance training
decreased three of the six anthropometric measures of total adiposity and increased
body mass and body mass index (BMI). Resistance training had no impact on the
measures of centrally located and abdominal adiposity. Body mass and BMI should
be used with caution in risk calculations and measures of total adiposity in
individuals engaging in resistance training due to this mode of training increasing
lean mass (and thus body mass and BMI). Resistance training reduced total adiposity
but did not provide an effective stimulus to lower centrally located and abdominal
adiposity.
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Clavel, Maïca. "Activité du trou noir supermassif au centre de la Galaxie". Thesis, Paris 11, 2014. http://www.theses.fr/2014PA112170/document.
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Le centre de la Galaxie abrite un trou noir supermassif, Sagittarius A*. Sa proximité en fait un laboratoire privilégié pour étudier les phénomènes d’accrétion à l’œuvre autour des trous noirs et contraindre le cycle d’activité de ces astres. Sgr A* est actuellement extrêmement peu lumineux et malgré des sursauts d’activité quotidiens sa luminosité demeure au moins huit ordres de grandeur en dessous de sa luminosité d’Eddington. Cet objet est ainsi l’un des trous noirs supermassifs connus les moins lumineux. Les mécanismes radiatifs à l’origine des variations quotidiennes observées ne sont pas clairement identifiés. Nous présentons les résultats d’une campagne d’observation multi-longueurs d’onde visant à mesurer le spectre de ces événements simultanément en rayons X et en infrarouge proche, à l’aide de l’observatoire XMM-Newton et de l’instrument VLT/NACO. Les données infrarouges obtenues grâce à la technique de spectro-imagerie en bande large ont permis d’étudier la variabilité du spectre de Sgr A* en infrarouge. Les incertitudes liées aux erreurs systématiques sont encore importantes mais les premiers tests réalisés semblent indiquer que l’indice spectral pourrait dépendre de la luminosité du trou noir. Sur des échelles de temps plus grandes, nous montrons également que Sgr A* n’a pas toujours été aussi peu actif. Des traces de son activité passée sont en effet visibles dans la matière moléculaire directement autour du trou noir, notamment sous la forme d’un rayonnement réfléchi visible dans la raie de fluorescence du fer à 6.4 keV. Nous avons réalisé une étude complète et systématique des variations de cette émission détectée dans la zone moléculaire centrale en utilisant les observatoires Chandra et XMM-Newton. Nos résultats confirment que Sgr A* a connu des sursauts intenses au cours des derniers siècles, au moins six ordre de grandeur en dessus de la luminosité actuelle. En particulier, nous avons mis en évidence, pour la première fois, la présence de deux événements transitoires distincts de relativement courte durée, probablement liés à des événements catastrophiques. Ces résultats constituent une première étape pour relier l’activité de ce trou noir spécifique aux autres noyaux de galaxie présents dans l’UniversSagittarius A⋆ is the supermassive black hole at the Galactic center. Due to its proximity, this specimen is an excellent laboratory to study the accretion processes occurring around black holes and to constrain the duty cycle of these objects. Sgr A* is currently extremely faint and despite the detection of daily flares, its luminosity remains at least eight orders of magnitude below its Eddington luminosity, making this specimen one of the least luminous known supermassive black holes. The radiative processes responsible for the daily variations of its luminosity have not been clearly identified yet. We present the results of a multi-wavelength campaign observing Sgr A* simultaneously in X-rays and in the near-infrared, using the XMM-Newton observatory and the VLT/NACO instrument. We studied the spectral variability of Sgr A* using the infrared data we obtained through a spectro-imaging technique. Uncertainties linked to the systematic errors are still large but the first tests applied seem to show that the spectral index of Sgr A* could depend on the black hole luminosity. On longer timescales, we demonstrate that Sgr A* experienced a higher level of activity in the recent past. Indeed, echoes of its past activity can be detected in the molecular material surrounding the black hole. They are traced by a strong signal in the iron fluorescence line at 6.4 keV. We achieved a complete and systematic study of this variable emission detected from the central molecular zone, using Chandra and XMM-Newton observatories. Our results confirm that Sgr A* experienced intense flares in the past few centuries, with a luminosity at least six orders of magnitude higher than its current one. In particular, we highlight for the first time the existence of two distinct transient events of relatively short duration, which are probably due to catastrophic events. These results are the first step needed to include Sgr A*’s activity into a broader understanding of the galactic nuclei
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Chirio, Jean. "Activité du SMUR dans le nouveau centre hospitalier de Dax". Bordeaux 2, 1989. http://www.theses.fr/1989BOR25284.
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Chang, Tae-Young. "User-activity aware strategies for mobile information access". Diss., Atlanta, Ga. : Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/22595.
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Thesis (Ph. D.)--Electrical and Computer Engineering, Georgia Institute of Technology, 2008.Committee Chair: Raghupathy Sivakumar; Committee Member: Chuanyi Ji; Committee Member: George Riley; Committee Member: Magnus Egerstedt; Committee Member: Umakishore Ramachandran.
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SOMMEREISEN, JEAN-PHILIPPE. "Activites des centres d'alcoologie de loire-atlantique de 1991 a 1993". Nantes, 1994. http://www.theses.fr/1994NANT048M.
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Speake, Helen. "Exploring the user-centred design of a physical activity pathway in NHS care". Thesis, Sheffield Hallam University, 2018. http://shura.shu.ac.uk/22412/.
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Background The UK National Health Service (NHS) has been identified as a key domain for tackling non-communicable diseases through reducing population physical inactivity. Research demonstrates that health professionals struggle to deliver existing physical activity (PA) interventions due to a perceived lack of time and confidence in behaviour change. Evidence also suggests that programmes are being delivered inconsistently. Existing interventions are failing to engage a sufficient range of patients and have not demonstrated a long term impact on patients' PA. As end users, patients and health professionals are fundamental to the success of PA interventions and must be actively involved in their design and evaluation. Method This study adopted a Research through Design methodology using the UK Design Council's Double Diamond framework (Discover, Define, Develop, Deliver; Design Council, 2007) to explore the user-centred design of a physical activity pathway in NHS care. Semi-structured interviews with 'users' (patients and health professionals) were undertaken. This was followed by a series of co-design workshops to identify specific problems and solutions. Users and other stakeholders were consulted via a survey, interviews and face-to-face consultations to test and refine solutions. A case study using one NHS service (Physioworks) was carried out to develop and evaluate implementation recommendations. Data was analysed throughout the process using inductive thematic analysis. Findings Popular solutions focused on making it easier for health professionals to initiate conversations about PA and ensuring that referral options were appropriate for patients. Novel elements of the pathway included priming patients prior to their appointment to normalise PA within the consultation, and feedback from PA providers to inform and positively reinforce health professionals' referral behaviours. Health professionals suggested that the co-designed pathway reflected a model of best practice but that traditional organisational constraints such as time pressures remained a barrier to its consistent use with patients. Further work is needed to refine and test the pathway and to ensure that it is helpful for a broad range of patients and professionals. Conclusions This research extends knowledge about the promotion of PA and the application of user-centred design in this context. Early impact of the research includes improvements within the clinical settings such as environmental prompts, establishment of graded introductory PA groups and streamlined appointment booking with PA providers. Further collaboration is planned with Physioworks NHS service to integrate the pathway into existing caseloads.
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Urbonaitė, Monika. "Išlaidų atsakomybės centrų formavimas ir jų veiklos vertinimas žemės ūkio verslo subjektuose". Master's thesis, Lithuanian Academic Libraries Network (LABT), 2013. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2013~D_20130621_131807-74072.
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Magistrantūros studijų baigiamasis darbas, 56 puslapiai, 18 paveikslų, 15 lentelių, 50 literatūros šaltinių, 7 priedai, lietuvių kalba.
PRASMINIAI ŽODŽIAI: apskaita pagal atsakomybės sritis, atsakomybės centrai, išlaidų atsakomybės centrai, išlaidų atsakomybės centrų formavimas, išlaidų atsakomybės centrų veiklos vertinimas.
Tyrimo objektas: išlaidų sukaupimas ir išlaidų efektyvumo vertinimas VšĮ „ASU mokomasis ūkis“.
Tyrimo tikslas: identifikuoti išlaidų kaupimo bei paskirstymo problemas, sukurti išlaidų kaupimo metodiką ir įvertinti išlaidų efektyvumą.
Uždaviniai:
1. VšĮ „ASU mokomasis ūkis“ pavyzdžiu išanalizuoti išlaidų kaupimą bei paskirstymą žemės ūkio verslo subjektuose ir identifikuoti problemas;
2. Išanalizuoti išlaidų atsakomybės centrų formavimo teorinius aspektus bei parengti išlaidų atsakomybės centrų formavimo modelį bei jo taikymo metodiką;
3. Parinkti išlaidų atsakomybės centrų veiklos vertinimo metodus;
4. Adaptuoti išlaidų atsakomybės centrų formavimo modelį VšĮ „ASU mokomasis ūkis“;
5. Įvertinti išlaidų atsakomybės centrų veiklą VšĮ „ASU mokomasis ūkis“.
Tyrimo metodai: mokslinės literatūros analizė bei sintezė, funkcinė klasifikavimo požymių dekompozicija, ekspertinis vertinimas, anketavimas, antrinių duomenų analizė, grafinis vaizdavimas.
Pirmoje darbo dalyje atlikta išlaidų kaupimo analizė VšĮ „ASU Mokomasis ūkis“ bei identifikuotos pagrindinės su išlaidų valdymu susijusios problemos.
Antroje darbo dalyje išnagrinėta atsakomybės centrų samprata... [toliau žr. visą tekstą]Graduation paper of Master’s studies, 56 pages, 18 Figures, 15 Tables, 50 references, 7 Appendices, in Lithuanian. KEY WORDS: records according to the spheres of responsibility, responsibility centers, cost responsibility centers, formation of cost responsibility centers, evaluation of activity of cost responsibility centers. Object of investigation: cost accumulation and evaluation of cost effectiveness in Public Institution (PI) “ASU Mokomasis Ūkis”. Aim of the investigation: to identify the problems of cost accumulation and distribution, to work out the methods of expenses accumulation and to evaluate the cost effectiveness. Objectives: 1. According to the example of PI “ASU Mokomasis Ūkis” to analyze the cost accumulation and distribution in the subjects of agricultural business and identify the problems; 2. To analyze the theoretic aspects of formation of cost responsibility centers and prepare the model of formation of cost responsibility centers and the methods of its application; 3. To choose the methods of evaluation of cost responsibility activity; 4. To adapt the model of formation of cost responsibility centers in PI “ASU Mokomasis Ūkis”; 5. To evaluate the activity of cost responsibility centers in PI “ASU Mokomasis Ūkis”. Methods of investigation: analysis and synthesis of scientific literature, functional decomposition of classification features, expert evaluation, questionnaire, analysis of secondary data, graphic depiction. Research results: In the first... [to full text]
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McIntosh, Paul. "Functional characterisation of voltage-gated potassium channels cloned from the mammalian central nervous system". Thesis, Imperial College London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.369251.
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Mytko, Dmytro, i Дмитро Митько. "Directions of offshore financial activity development in the conditions of globalization". Thesis, National aviation university, 2021. https://er.nau.edu.ua/handle/NAU/51239.
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1. Hetmantsev D. Opportunities and prospects of offshore business / D. Hetmantsev // Financial market of Ukraine. - 2010. - №5.
2. Grundy M. Offshore business centers: a world survey / M. Grundy, A. Nathan - London: Sweet & Maxwell, 2013.
3. Heifetz B.A. Offshore jurisdictions in the global and national economy / B.A. Heifetz. - Moscow: Economics, 2010.
4. The World Bank [Electronic source] - Resource access mode: http://www.worldbank.org.Offshore financial activities are the provision of financial services by banks or other financial institutions to non-residents. These are various operations on debt financing, attraction of deposits, trust management of clients' funds . Offshore zones have a number of features that distinguish them from other groups of countries with preferential taxation and create investment attractiveness for foreign investors. But a specific condition of the traditional (Classical) offshore is bound to obtain income, registered in this area companies outside this area.
Офшорна фінансова діяльність - це надання фінансових послуг банками чи іншими фінансовими установами нерезидентам. Це різні операції з боргового фінансування, залучення депозитів, довірчого управління коштами клієнтів. Офшорні зони мають ряд особливостей, що відрізняють їх від інших груп країн із пільговим оподаткуванням та створюють інвестиційну привабливість для іноземних інвесторів. Але конкретна умова традиційного (класичного) офшору зобов’язана отримувати дохід, зареєстрований у цій галузі компаніями, що не входять в цей район.
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Smith, M. Alex. "Estimating photolyase activity for seven amphibian species from south-central Ontario". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ40487.pdf.
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Darraillans, Didier. "Activité du service médical d'accueil du centre hospitalier de Bourgoin Jallieu". Lyon 1, 1991. http://www.theses.fr/1991LYO1M397.
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Baude, Marie-Louise. "Activite du service d'obstetrique du centre hospitalier de sarreguemines : annee 1982". Université Louis Pasteur (Strasbourg) (1971-2008), 1985. http://www.theses.fr/1985STR1M184.
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