Rozprawy doktorskie na temat „Acquired”
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Baxter-Versi, Doreen Mary. "Acquired spelling disorders". Thesis, University College London (University of London), 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.262683.
Pełny tekst źródłaQin, Xiaohui. "Papaya systemic acquired resistance". Thesis, University of Hawaii at Manoa, 2003. http://hdl.handle.net/10125/6872.
Pełny tekst źródłaxvi, 116 leaves
Potgieter, Peter Daniel. "Severe community-acquired pneumonia". Doctoral thesis, University of Cape Town, 1996. http://hdl.handle.net/11427/27658.
Pełny tekst źródłaCaddick, James M. "Molecular typing of hospital-acquired, community-acquired and multidrug-resistant methicillin-resistant staphylococcus aureus". Thesis, Aston University, 2005. http://publications.aston.ac.uk/11028/.
Pełny tekst źródłaCipolotti, Lisa. "Acquired disorders of numerical processing". Thesis, University College London (University of London), 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242400.
Pełny tekst źródłaBradley, Veronica A. "Varieties of acquired phonological dyslexia". Thesis, Aston University, 1985. http://publications.aston.ac.uk/12145/.
Pełny tekst źródłaWootton, Daniel. "Recovery from community acquired pneumonia". Thesis, University of Liverpool, 2015. http://livrepository.liverpool.ac.uk/2028510/.
Pełny tekst źródłaVasilescu, Camelia. "Earnings management in acquired companies". Thesis, University of Leeds, 2014. http://etheses.whiterose.ac.uk/8388/.
Pełny tekst źródłaJones, Druscilla Willis. "Hospital-Acquired Pressure Ulcer Prevention". ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/7670.
Pełny tekst źródłaJones, Kevin Dominic. "Psychological adjustment to acquired brain injury". Thesis, University of Oxford, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.556195.
Pełny tekst źródłaPearson, Corinne. "Substance use and acquired brain injury". Thesis, University of Southampton, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.419003.
Pełny tekst źródłaNÄSMAN, MARKUS. "Detecting Hospital Acquired Infections usingMachine Learning". Thesis, KTH, Skolan för datavetenskap och kommunikation (CSC), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-142355.
Pełny tekst źródłaVarje år ådrar sig en stor andel sjukhuspatienter infektioner på grund av sin sjukhusvistelse. Dessa infektioner är ett stort patientsäkerhetsproblem som leder till ökad mortalitet och morbiditet för de drabbade patienterna. Manuell detektion och inrapportering av dessa infektioner leder till merarbete för sjukvårdspersonalen vilket försvårar att detta sker kontinuerligt. Målet är att automatisera detektionen med hjälp av maskininlärning. Detta kommer att göras genom att använda övervakad inlärning och data tillgänglig i elektroniska patientjournaler. Då det mesta av den tillgängliga information endast är tillgänglig som fritext så ligger fokuset för denna uppsats på hur man kan förvandla texten till särdrag som kan fånga de mönster som är karakteristiska för vårdrelaterade infektioner. Tre olika datarepresentationer utforskas: termfrekvenser, komplexa symboliska sekvenser och “enkla parametrar” baserade på informationsextraktion. De klassificerare som används är stödvektormaskiner (support vector machines) och “gradient tree boosting”. Datamängden som används består av 300 vårdtillfällen från Karolinska Universitetssjukhuset från 2011 och 2012. Vårdtillfällena har markerats som innehållandes en vårdrelaterad infektion eller ej av sjukvårdspersonal. Av dessa vårdtillfällen har 53% markerats som innehållandes en vårdrelaterad infektion och 47% har markerats som ej innehållande en vårdrelaterad infektion. Stödvektormaskiner och “gradient tree boosting” presterar snarlikt för uppgiften men fokus ligger på sistnämnda metod då resultatet delvis kan visualiseras. Bäst resultat uppnås med “gradient tree boosting”m utvärderat med 5-delad korsvalidering. Detta ger ett F1-värde i intervallet 0,82 - 0,83, täckning i intervallet 0,88 - 0,89 och 0,78 i precision oavsett vilken av datarepresentationerna som används. Framtida arbete bör fokusera på hur man kan inlemma fler parametrar i de informationsextraktionsbaserade representationerna, hur man kan hitta mönster som är vanliga i en specifik subklass men inte i huvudklassen, samt hur väl de olika datarepresentationerna fungerar för större datamängder.
Butterfill, Stephen Andrew. "Beliefs and how they are acquired". Thesis, University of Oxford, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288914.
Pełny tekst źródłaSargeant, Malcolm. "Implementation of the Acquired Rights Directive". Thesis, Middlesex University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337841.
Pełny tekst źródłaGray, Colin. "The enterprise culture : an acquired taste?" Thesis, London Metropolitan University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283087.
Pełny tekst źródłaWard-Robinson, Jasper. "An associative account of acquired equivalence". Thesis, University of York, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.319455.
Pełny tekst źródłaWilliams, Geraint P. "Immunoregulation of acquired ocular immunobullous disease". Thesis, University of Birmingham, 2012. http://etheses.bham.ac.uk//id/eprint/3235/.
Pełny tekst źródłaWhitelaw, D. A., i D. A. Whitelaw. "Community acquired bacteraemia in the elderly". Master's thesis, University of Cape Town, 1990. http://hdl.handle.net/11427/24974.
Pełny tekst źródłaBonilla, Ingrid Marie. "Acquired Electrophysiological Remodeling and Cardiac Arrhythmias". The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1396024058.
Pełny tekst źródłaSalas, Christian E. "Emotion regulation after acquired brain injury". Thesis, Bangor University, 2013. https://research.bangor.ac.uk/portal/en/theses/emotion-regulation-after-acquired-brain-injury(6bcd1d9b-8e25-43b6-ae26-d350cfd2c750).html.
Pełny tekst źródłaJonsson, Gustav, i Ehsan Ullah. "Acculturation: The view of the acquired". Thesis, Uppsala universitet, Företagsekonomiska institutionen, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-388947.
Pełny tekst źródłaLittleson, Steven G. "Strategies to Reduce Hospital-Acquired Conditions". ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/6605.
Pełny tekst źródłaHo, Tip-yin. "Community-acquired pneumonia in elderly requiring hospitalization". Click to view the E-thesis via HKUTO, 2004. http://sunzi.lib.hku.hk/hkuto/record/B31971787.
Pełny tekst źródłaSebastián, Romagosa Marc. "Brain computer interfaces for brain acquired damage". Doctoral thesis, Universitat Autònoma de Barcelona, 2020. http://hdl.handle.net/10803/670835.
Pełny tekst źródłaEl término Interfaz Cerebro-Computadora (ICC) surgió en los años 70 por el Dr. Jacques J. Vidal, que mediante el uso de la electroencefalografía (EEG) trató de dar una salida alternativa a las señales del cerebro para controlar un dispositivo externo. El objetivo principal de esta hazaña era ayudar a los pacientes con problemas de movimiento o comunicación a relacionarse con el entorno. Desde entonces, muchos neurocientíficos han utilizado esta idea y han tratado de ponerla en práctica utilizando diferentes métodos de adquisición y procesamiento de señales, nuevos dispositivos de interacción y nuevas metas y objetivos. Todo ello ha facilitado la aplicación de esta tecnología en muchas áreas y actualmente las ICC se utilizan para jugar a videojuegos, mover sillas de ruedas, facilitar la escritura en personas sin movilidad, establecer criterios y preferencias de compra en el mundo del comercio y el consumo, o incluso pueden servir como detector de mentiras. Sin embargo, el sector que presenta un mayor avance y desarrollo de las ICC es el sector biomédico. A grandes rasgos podemos utilizar las ICC con dos finalidades distintas dentro de la neurorehabilitación; sustituir una función perdida o inducir cambios en la plasticidad neuronal con el objetivo de restaurar o compensar dicha función perdida. Hay diferentes principios para el registro de las señales del cerebro; de forma invasiva, colocando los electrodos de registro dentro de la cavidad craneal, o no invasiva, colocando los electrodos de registro fuera de la cavidad craneal. El método más conocido y difundido es la EEG. Su uso es adecuado para entornos clínicos, tiene una resolución temporal muy precisa y su retroalimentación en tiempo real puede inducir la plasticidad cortical y el restablecimiento de la función motora normal. En esta tesis presentamos tres objetivos diferentes: (1) evaluar los efectos clínicos de la rehabilitación mediante las ICC en pacientes con ictus, ya sea realizando un meta-análisis de los estudios publicados o evaluando los cambios funcionales en los pacientes con ictus después de la terapia de ICC; (2) explorar parámetros alternativos para cuantificar los efectos de las ICC en pacientes con ictus, evaluando diferentes biomarcadores de electroencefalografía en pacientes con esta patología y correlacionando los posibles cambios en estos parámetros con los resultados en las escalas funcionales; (3) optimizar el sistema ICC utilizando mediante la gamificación de un avatar.
The term Brain Computer Interface (BCI) emerged in the 70's by Dr. Jacques J Vidal, who by using electroencephalography (EEG) tried to give an alternative output to the brain signals in order to control an external device. The main objective of this feat was to help patients with impaired movement or communication to relate themselves to the environment. Since then many neuroscientists have used this idea and have tried to implement it using different methods of signal acquisition and processing, new interaction devices, new goals and objectives. All this has facilitated the implementation of this technology in many areas and currently BCI is used to play video games, move wheelchairs, facilitate writing in people without mobility, establish criteria and purchase preferences in the world of marketing and consumption, or even serve as a lie detector. However, the sector that presents the most marked progress and development of BCI is the biomedical sector. In rough outlines we can use BCI with two different purposes within the neurorehabilitation; to substitute a lost function or to induce neural plasticity changes with the aim to restore or compensate the lost function. To restore a lost function by inducing neuroplastic changes in the brain is undoubtedly a challenging strategy but a feasible goal through BCI technology. This type of intervention requires that the patient invests time and effort in a therapy based on the practice of motor image and feedback mechanisms in real time. There are different principles to record the brain signals; invasively, placing the recording electrodes inside the cranial cavity, or non-invasive, placing the recording electrodes outside of the cranial cavity. The best known and most widespread one is EEG, since they are suitable for clinical environments, have a highly accurate temporal resolution and their real-time feedback can induce cortical plasticity and the restoration of normal motor function. On this thesis we present three different objectives: (1) to evaluate the clinical effects of rehabilitation based on BCI system in stroke patients, either by performing a meta-analysis of published studies or by evaluating functional changes in stroke patients after BCI training; (2) to explore alternative parameters to quantify effects of BCI in stroke patients, by evaluating different electroencephalography biomarkers in stroke patients and correlating potential changes in these parameters with functional scales; (3) to optimize the BCI system by using a new gamified avatar.
Powell, Trevor J. "Working with people with acquired brain injury". Thesis, University of Surrey, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298039.
Pełny tekst źródłaPancaroglu, Raika. "Eye region processing : insights from acquired prosopagnosia". Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/49942.
Pełny tekst źródłaMedicine, Faculty of
Graduate
May, Michelle. "Socio-emotional behaviour following acquired brain injury". Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/16445.
Pełny tekst źródłaHo, Tip-yin, i 何蝶燕. "Community-acquired pneumonia in elderly requiring hospitalization". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B31971787.
Pełny tekst źródłaScott, Eileen Margaret. "Hospital acquired pressure sores in surgical patients". Thesis, Teesside University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.417233.
Pełny tekst źródłaCoote, Peter John. "Mechanisms of acquired thermotolerance in Saccharomyces cerevisiae". Thesis, University of Nottingham, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335420.
Pełny tekst źródłaChagger, Pabhinder Singh. "Stigma, nurses and acquired immune deficiency syndrome". Thesis, University of Southampton, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242496.
Pełny tekst źródłaBrennan, Andrew. "Coping and adjustment following acquired brain injury". Thesis, University of Birmingham, 2002. http://etheses.bham.ac.uk//id/eprint/637/.
Pełny tekst źródłaLefevre, Thierry. "Segmentation of irises acquired in degraded conditions". Thesis, Evry, Institut national des télécommunications, 2013. http://www.theses.fr/2013TELE0005/document.
Pełny tekst źródłaThis thesis is focused on the development of robust segmentation algorithms for iris recognition systems working in degraded acquisition conditions. In controlled acquisition scenarios, iris segmentation is well handled by simple segmentation schemes, which modeled the iris borders by circles and assumed that the iris can only be occluded by eyelids. However, such simple models tend to fail when the iris is strongly occluded or off-angle, or when the iris borders are not sharp enough. In this thesis, we propose a complete segmentation system working efficiently despite the above-mentioned degradations of the input data. After a study of the recent state of the art in iris recognition, we identified four key issues that an iris segmentation system should handle when being confronted to images of poor quality, leading this way to four key modules for the complete system: • The system should be able locate the pupil in the image in order to initialize more complex algorithms. To address this problem, we propose an original and effective way to first segment dark elements in the image that can lead to mistakes of the pupil localization process. This rough segmentation detects high frequency areas of the image and then the system uses the pupil homogeneity as a criterion to identify the pupil area among other dark regions of the image. • Accurate segmentation of the iris texture in the eye image is a core task of iris segmentation systems. We propose to segment the iris texture by Active Contours because they meet both the requirement in robustness and accuracy required to perform segmentation on large databases of degraded images. We studied several Active Contours that varies in speed, robustness, accuracy and in the features they use to model the iris region. We make a comparative evaluation of the algorithms’ influence on the system performance. • A complete segmentation system must also accurately estimate the iris shape in occluded regions, in order to format the iris texture for recognition. We propose a robust and accurate scheme based on a variational formulation to fit an elliptic model on the iris borders. We explicitly derive evolution equations for ellipses using the Active Contours formalism. We also propose an effective way to limit the sensitivity of this process to initial conditions. This part of our work is currently under review for final acceptance in the international journal Computer Vision and Image Understanding (CVIU). • Finally, we address the main issue of automatic detection of segmentation failures of the system. Few works in the literature address measuring the quality of a segmentation algorithm, critical task for an operational system. We propose in this thesis a set of novel quality measures for segmentation and show a correlation between each of them with the intrinsic recognition performance of the segmented images. We perform fusion of the individual quality measures via a Support Vector Regression (SVR) algorithm, in order to propose a more robust global segmentation quality score
McFaline-Figueroa, José L. "Mechanism of acquired temozolomide resistance in glioblastoma". Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/89944.
Pełny tekst źródłaCataloged from PDF version of thesis.
Includes bibliographical references.
Glioblastoma (GBM) is the most common and malignant form of brain cancer. After aggressive treatment, therapy resistant tumors inevitably recur. However, the molecular mechanisms underlying such resistance remain unclear. We isolated GBM cells resistant to temozolomide (TMZ), the frontline chemotherapy agent for GBM, and observed modest decreases in the mismatch repair (MMR) components MSH2 and MSH6. The modest decrease in MSH2, and relatively modest decrease in MSH6, did not seem sufficient to account for the very large increase in TMZ resistance. However, shRNA-mediated modulation of MSH2 and MSH6 levels in vitro confirmed that such decreases in MSH2 and MSH6 provide a potent mechanism for TMZ resistance. We demonstrate in an in vivo GBM mouse model that minor changes in MSH2 suppress TMZ-induced tumor regression, and moreover, show that even minor decreases in MSH2 transcript levels correlate with decreased survival in TMZ treated GBM patients. These modest changes in MMR are unlikely to alter classical markers of MMR deficiency, namely microsatellite instability and a mutator phenotype. Our results suggest that the involvement of MMR deregulation in mediating TMZ resistance is likely to be much more prevalent than previously appreciated. Additionally, we have employed phosphoproteomic network analysis to identify changes at the signaling network level that accompany the acquisition of TMZ resistance. Through mathematical and computational approaches, we identified changes that suggest increased PDGFR and integrin/FAK1 signaling in response to repeated TMZ exposure. Additionally, kinase motif analysis identified widespread alterations in phosphorylation of peptides containing motifs associated with the CDK/MAPK kinase family. Currently, we are applying molecular biology techniques to investigate the effects of these altered cellular signals on MMR activity and the sensitivity of GBM cells to TMZ.
by José L. McFaline-Figueroa.
Ph. D.
Hellal, Paula Joanne. "Acquired childhood aphasia : historical and theoretical perspectives". Thesis, Birkbeck (University of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413628.
Pełny tekst źródłaMurphy, Maggie M. "Impaired self-awareness following acquired brain injury". Thesis, Oxford Brookes University, 2005. https://radar.brookes.ac.uk/radar/items/113cb7c4-9ee0-4481-a0a2-65afa5ccafd6/1/.
Pełny tekst źródłaHocking, Sian Elin. "Parental adjustment in paediatric acquired brain injury". Thesis, University of Exeter, 2015. http://hdl.handle.net/10871/18329.
Pełny tekst źródłaTyerman, Emma. "Family experience after paediatric acquired brain injury". Thesis, Lancaster University, 2015. http://eprints.lancs.ac.uk/76531/.
Pełny tekst źródłaNiemeyer, Marcus. "NKT cells between innate and acquired immunity". Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2005. http://dx.doi.org/10.18452/15330.
Pełny tekst źródłaThe function and specificity of Natural Killer T (NKT) cells in innate and acquired immunity still remains elusive. The vast majority of CD1d restricted NKT cells recognise alpha-galactosylceramid (alphaGalCer), derived from a marine sponge, a lipid of unclear physiological significance. Different mycobycterial glycolipids were isolated and examined for binding to CD1d as well as for their capacity of NKT cell stimulation. Phospatidylinositol-mannoside (PIM) derived from Mycobacterium bovis BCG was identified as the first bacterial lipid antigen presented by CD1d. PIM activated both murine and human NKT cells to secrete IFN-gamma but not IL-4 in a CD1d dependent manner. Additionally, several other lipid fractions with NKT cell activation capacities were identified. This activation was either a direct, T-cell-receptor (TCR) mediated and/or an indirect, toll-like-receptor 2 (TLR2) mediated activation. Iso-globotrihexosylceramide (iGb3) was described as the endogenous NKT cell antigen. iGb3 is a ubiquitously present lysosomal glycolipid which raises the question of regulation of antigen availability and NKT cell activation control. It could be shown that regulation of antigen availability plays a crucial role in regulation of NKT cell activation. Moreover, uncontrolled appearance and increased concentrations of the endogenous antigen iGb3 led to substantial decrease in NKT cell number, presumably by activation induced cell death. Using DNA Microarray analysis, the gene expression profiles of naïve NKT cells and classical CD4 T cells, regulatory T cells, NK cells as well as to activated NKT cells were compared. The profiles revealed a NKT cell specific gene expression pattern as well as expression of genes which NKT cells share with NK cells, conventional CD4+ T cells and Treg cells. Both, naïve and activated NKT cells display elevated expression of apoptosis regulating genes providing NKT cells with high degree of self-control to precisely regulate their own activity.
Lynch, Janet. "THE FINANCIAL PERFORMANCE OF SYSTEM ACQUIRED HOSPITALS". VCU Scholars Compass, 1988. https://scholarscompass.vcu.edu/etd/5224.
Pełny tekst źródłaLamorgese, Michael. "Early Recognition and Treatment of Acquired Pneumonia". ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/5741.
Pełny tekst źródłaBirmingham, Robert B. "Intellectual property rights in software acquired by DoD". Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 1995. http://handle.dtic.mil/100.2/ADA305992.
Pełny tekst źródłaRuhe, Jakob, i Johan Nordin. "Classification of Points Acquired by Airborne Laser Systems". Thesis, Linköping University, Department of Electrical Engineering, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-10485.
Pełny tekst źródłaDuring several years research has been performed at the Department of Laser Systems, the Swedish Defense Research Agency (FOI), to develop methods to produce high resolution 3D environment models based on data acquired with airborne laser systems. The 3D models are used for several purposes, both military and civilian applications, for example mission planning, crisis management analysis and planning of infrastructure.
We have implemented a new format to store laser point data. Instead of storing rasterized images of the data this new format stores the original location of each point. We have also implemented a new method to detect outliers, methods to estimate the ground surface and also to divide the remaining data into two classes: buildings and vegetation.
It is also shown that it is possible to get more accurate results by analyzing the points directly instead of only using rasterized images and image processing algorithms. We show that these methods can be implemented without increasing the computational complexity.
Hagberg-van't, Hooft Ingrid. "Cognitive rehabilitation in children with acquired brain injuries /". Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-380-9/.
Pełny tekst źródłaSmith, Michelle Adrienne. "The transaction financing decision, overinvestment, and acquired goodwill /". Title page, contents and abstract only, 1996. http://web4.library.adelaide.edu.au/theses/09C/09cs655.pdf.
Pełny tekst źródłaJassem, Agatha Natalie. "Aminoglycoside susceptibility and acquired resistance in Burkholderia vietnamiensis". Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/42154.
Pełny tekst źródłaPernhorst, Katharina [Verfasser]. "Molecular genetic analyses in acquired epilepsies / Katharina Pernhorst". Bonn : Universitäts- und Landesbibliothek Bonn, 2014. http://d-nb.info/1047622750/34.
Pełny tekst źródłaCarapeti, Melina. "Identification of acquired genetic changes in acute leukaemia". Thesis, Imperial College London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287882.
Pełny tekst źródłaBewick, Thomas. "Improving outcomes in patients with community-acquired pneumonia". Thesis, University of Nottingham, 2012. http://eprints.nottingham.ac.uk/12432/.
Pełny tekst źródłaSato, Hitomi. "Acquired dyslexia in Japanese : implications for reading theory". Thesis, University College London (University of London), 2007. http://discovery.ucl.ac.uk/1334689/.
Pełny tekst źródła