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Artykuły w czasopismach na temat "A-618"

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VanScoy, Brian D., Michael Trang, Jennifer McCauley, Haley Conde, Sujata M. Bhavnani, Lawrence V. Friedrich, Dylan C. Alexander i Paul G. Ambrose. "Pharmacokinetics-Pharmacodynamics of a Novel β-Lactamase Inhibitor, CB-618, in Combination with Meropenem in anIn VitroInfection Model". Antimicrobial Agents and Chemotherapy 60, nr 7 (21.03.2016): 3891–96. http://dx.doi.org/10.1128/aac.02943-15.

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ABSTRACTThe usefulness of β-lactam antimicrobial agents is threatened as never before by β-lactamase-producing bacteria. For this reason, there has been renewed interest in the development of broad-spectrum β-lactamase inhibitors. Herein we describe the results of dose fractionation and dose-ranging studies carried out using a one-compartmentin vitroinfection model to determine the exposure measure for CB-618, a novel β-lactamase inhibitor, most predictive of the efficacy when given in combination with meropenem. The challenge panel includedEnterobacteriaceaeclinical isolates, which collectively produced a wide range of β-lactamase enzymes (KPC-2, KPC-3, FOX-5, OXA-48, SHV-11, SHV-27, and TEM-1). Human concentration-time profiles were simulated for each drug, and samples were collected for drug concentration and bacterial density determinations. Using data from dose fractionation studies and a challengeKlebsiella pneumoniaeisolate (CB-618-potentiated meropenem MIC = 1 mg/liter), relationships between change from baseline in log10CFU/ml at 24 h and each of CB-618 area under the concentration-time curve over 24 h (AUC0–24), maximum concentration (Cmax), and percentage of the dosing interval that CB-618 concentrations remained above a given threshold were evaluated in combination with meropenem at 2 g every 8 h (q8h). The exposure measures most closely associated with CB-618 efficacy in combination with meropenem were the CB-618 AUC0–24(r2= 0.835) andCmax(r2= 0.826). Using the CB-618 AUC0–24indexed to the CB-618-potentiated meropenem MIC value, the relationship between change from baseline in log10CFU/ml at 24 h and CB-618 AUC0–24/MIC ratio in combination with meropenem was evaluated using the pooled data from five challenge isolates; the CB-618 AUC0–24/MIC ratio associated with net bacterial stasis and the 1- and 2-log10CFU/ml reductions from baseline at 24 h were 27.3, 86.1, and 444.8, respectively. These data provide a pharmacokinetics-pharmacodynamics (PK-PD) basis for evaluating potential CB-618 dosing regimens in combination with meropenem in future studies.
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WOEGINGER, GERHARD J. "A NOTE ON FAIR DIVISION UNDER INTERVAL UNCERTAINTY". International Journal of Uncertainty, Fuzziness and Knowledge-Based Systems 14, nr 06 (grudzień 2006): 753–56. http://dx.doi.org/10.1142/s021848850600431x.

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In a recent paper [International Journal of Uncertainty, Fuzziness, and Knowledge-Based Systems 8:611–618], Yager & Kreinovich characterize a certain proportional division rule in terms of the three axioms (1) symmetry, (2) participant mergability, and (3) continuity. This technical note tightens their characterization: The proportional division rule is already fully characterized by the first two axioms (1) symmetry and (2) participant mergability.
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Maiti, R., P. Vidyasagar i P. Banerjee. "Characterization of salinity tolerance in rice ( Oryza sativa L.) genotypes at the germination and seedling stages". Acta Agronomica Hungarica 56, nr 2 (1.06.2008): 139–47. http://dx.doi.org/10.1556/aagr.56.2008.2.3.

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The present work was conducted to study the genotypic variability of rice genotypes at the germination and seedling stages at different levels of salinity (0 M, 0.15 M, 0.2 M and 0.25 M NaCl). The results showed that increasing salinity decreased germination and seedling growth. Significant genotypic variability exists in the germination and seedling stages in response to different NaCl concentrations. Most of the genotypes showed more than 90% germination in the control, indicating good seed vigour. Two genotypes, VBR 638 (93%) and VBR 644 (84%), were selected as being tolerant to salinity at 0.2 M NaCl at the germination stage. Therefore, these could be used as source materials for genetic improvement for salinity tolerance at the germination stage. A considerable amount of genotypic variability was also found under control and saline conditions at the seedling stage with respect to the variables shoot height, root length, shoot and root dry weight. The high heritability observed for these variables offers good scope for genetic improvement for salinity tolerance both at the germination and seedling stages. The genotypes VBR 616, VBR 628, VBR 645, VBR 640, VBR 611, VBR 620, VBR 612, VBR 618, VBR 644, VBR 629, VBR 625 and VBR 630 were selected as being tolerant to salinity at the seedling stage.
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Radanova, Maria, Galya Mihaylova, Zhasmina Mihaylova, Desislava Ivanova, Oskan Tasinov, Neshe Nazifova-Tasinova, Pavel Pavlov, Milko Mirchev, Nikolay Conev i Ivan Donev. "Circulating miR-618 Has Prognostic Significance in Patients with Metastatic Colon Cancer". Current Oncology 28, nr 2 (15.03.2021): 1204–15. http://dx.doi.org/10.3390/curroncol28020116.

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The present study evaluated the prognostic role of circulating miRNA-618 in patients with metastatic colon cancer (mCC) and whether miR-618 gene rs2682818 single nucleotide polymorphisms (SNP) are associated with colon cancer susceptibility and expression levels of mature miR-618. In total, 104 patients with mCC before starting the chemotherapy were investigated. The expression status of circulating miR-618 in mCC was evaluated by quantitative PCR. TaqMan PCR assay was used for rs2682818 SNP genotyping. miR-618 was overexpressed in serum of mCC patients. Patients with high and intermediate expression of miR-618 had a significantly longer mean overall survival (OS) of 21 months than patients with low expression—16 months. In addition, multivariate Cox regression analysis confirmed the association between high/intermediate levels of miRNA-618 and longer OS, HR = 0.51, 95% CI: 0.30–0.86, p = 0.012. miR-618 rs2682818 SNP significantly decreased the risk of colon cancer susceptibility in both heterozygous codominant (AC vs. CC, OR = 0.39, 95% CI: 0.17–0.88, p = 0.024) and overdominant (AC vs. CC + AA, OR = 0.37, 95% CI: 0.16–0.85, p = 0.018) genetic models. Our data suggest that circulating miRNA-618 could be useful as a prognostic biomarker in mCC. Patients harboring AC rs2682818 genotype have a decreased risk for colon cancer in comparison with patients with CC and AA genotypes.
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Machens, Andreas, Steffen Hauptmann i Henning Dralle. "Modification of multiple endocrine neoplasia 2A phenotype by cell membrane proximity of RET mutations in exon 10". Endocrine-Related Cancer 16, nr 1 (marzec 2009): 171–77. http://dx.doi.org/10.1677/erc-08-0096.

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Rearranged during transfection (RET) germ-line mutations in exon 10 are peculiar because they produce both gain-of-function multiple endocrine neoplasia 2A and loss-of-function Hirschsprung's disease phenotypes. Drawing on 38 medullary thyroid cancer patients harboring germ-line mutations in codon 620 (n=8), 618 (n=19), 611 (n=10), and 609 (n=1), this study aimed to test the hypothesis that closer proximity of RET germ-line mutations in exon 10 to the cell membrane may translate into earlier or more advanced disease. The closer mutations in codon 620, 618, and 611 were located to the transmembrane domain (codons 657–636) of the RET receptor, the greater were mean primary tumor diameters (23.5, 18.7, and 7.5 mm, P=0.020), the frequency of lymph node metastasis (75, 68, and 30%, P=0.11) and pheochromocytoma (38, 16, and 0%, P=0.11). Periods of observation were broadly comparable for these groups (mean age 33.4–39.3 years; P=0.71). When mutations in adjoining codons were collapsed (codons 620/618 vs 611/609), the differences in mean primary tumor diameter (20.1 vs 7.4 mm, P=0.005) and lymph node metastasis (70 vs 36%; P=0.07) were accentuated. Compared with 80 carriers of exon 11 mutations (codon 634, n=78; codon 630, n=2), the 38 carriers of exon 10 mutations, which are rarer and confer a weaker transforming activity in vitro than exon 11 mutations, required significantly more time to develop fewer tumors. Although limited in numbers, these data suggested that membrane proximity is an important determinant of tumor development in carriers of RET mutations in exon 10.
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Wu, Lingling, Wenjun Fu, Yiyang Cao, Shuo Zhao, Yuchen Zhang, Xiaonan Li, Naijun Dong i in. "Inhibiting miR–618 Promotes Keratinocytes Proliferation and Migration to Enhance Wound Healing in Mice". International Journal of Molecular Sciences 25, nr 14 (11.07.2024): 7617. http://dx.doi.org/10.3390/ijms25147617.

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The delay in wound healing caused by chronic wounds or pathological scars is a pressing issue in clinical practice, imposing significant economic and psychological burdens on patients. In particular, with the aging of the population and the increasing incidence of diseases such as diabetes, impaired wound healing is one of the growing health problems. MicroRNA (miRNA) plays a crucial role in wound healing and regulates various biological processes. Our results show that miR–618 was significantly upregulated during the inflammatory phase of wound healing.Subsequently, miR–618 promotes the secretion of pro–inflammatory cytokines and regulates the proliferation and migration of keratinocytes. Mechanistically, miR–618 binds to the target gene–Atp11b and inhibits the PI3K–Akt signaling pathway, inhibiting the epithelial–mesenchymal transition (EMT) of keratinocytes. In addition, the PI3K–Akt signaling pathway induces the enrichment of nuclear miR–618, and miR–618 binds to the promoter of Lin7a to regulate gene transcription. Intradermal injection of miR–618 antagomir around full–thickness wounds in peridermal mice effectively accelerates wound closure compared to control. In conclusion, miR–618 antagomir can be a potential therapeutic agent for wound healing.
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Postma, J., i H. Rattink. "Biological control of Fusarium wilt of carnation with a nonpathogenic isolate of Fusarium oxysporum". Canadian Journal of Botany 70, nr 6 (1.06.1992): 1199–205. http://dx.doi.org/10.1139/b92-150.

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The nonpathogenic isolate 618-12 of Fusarium oxysporum, wild type as well as a benomyl-resistant mutant, suppressed Fusarium wilt (F. o. f.sp. dianthi) in a susceptible cultivar of carnation by 80%. Two other nonpathogenic isolates had a similar effect. Suppression by isolate 618-12 occurred only when antagonist and pathogen were both added to the soil but not if they were introduced at a different location (one in the stem, the other in the soil). Thus systemic induced resistance could not be demonstrated. In treatments where isolate 618-12 and the pathogen were both introduced into the soil, fewer plants showed symptoms, disease severity was less, and colonization by the pathogen was less extensive than after inoculation with the pathogen alone. After soil inoculation, the nonpathogenic isolate 618-12 was recovered from the stem, sometimes at a height of 60 cm. Key words: colonization, carnation stem, soil.
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Pattersons, Muhammad Lawrence, i Isnaeni Isnaeni. "ANALISIS PENGARUH PENAMBAHAN NANOPARTIKEL EMAS TERHADAP INTENSITAS EMISI DAN WAKTU PELURUHAN FOTOLUMINESENSI KUANTUM DOT CDSE 618". Spektra: Jurnal Fisika dan Aplikasinya 3, nr 1 (30.04.2018): 23–30. http://dx.doi.org/10.21009/spektra.031.04.

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Abstrak Telah dilakukan pencampuran nanopartikel emas dengan kuantum dot CdSe 618. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh penambahan nanopartikel emas terhadap intensitas emisi dan waktu peluruhan fotoluminesensi kuantum dot CdSe 618. Dalam 2 mL kuantum dot CdSe 618, ditambahkan nanopartikel emas sebanyak 40 µL, 80 µL, dan 120 µL. Pada setiap penambahan tersebut, dilakukan pengujian fotoluminesensi dan time-resolved photoluminescence, masing-masing untuk mengetahui intensitas emisi dan waktu peluruhan fotoluminesensi kuantum dot CdSe 618 setelah ditambahkan dengan nanopartikel emas. Dilakukan pula pengukuran terhadap rentang panjang gelombang absorpsi dari nanopartikel emas, beserta ukuran diameter partikel-partikelnya. Hasil pengujian menunjukkan bahwa secara keseluruhan, intensitas emisi kuantum dot CdSe 618 setelah ditambahkan dengan nanopartikel emas menjadi lebih rendah, dan nilai waktu peluruhan fotoluminesensi menjadi lebih besar. Penurunan intensitas emisi dan peningkatan waktu peluruhan fotoluminesensi diakibatkan oleh kemunculan plasmon pada nanopartikel emas. Kata-kata kunci: nanopartikel emas, kuantum dot, fotoluminesensi. Abstract We have done the mixing of gold nanoparticles and CdSe 618 quantum dots. The purpose of this study is to see the influence of gold nanoparticles increment to emission intensity and photoluminescence decay time of CdSe 618 quantum dots. Into 2 mL of CdSe 618 quantum dots, we added gold nanoparticles as much as 40 µL, 80 µL, and 120 µL. At each adding, we did photoluminescence and time-resolved photoluminescence testings, to see emission intensity and photoluminescence time decay of CdSe 618 quantum dots after the adding of gold nanoparticles. We also did a measurement of absorption wavelength range of gold nanoparticles, along with diameter size of the particles. The results showed that, overall, the emission intensity of CdSe 618 quantum dots became lower after the adding of gold nanoparticles, and the value of photoluminescence decay time became bigger. The decrease of emission intensity and the increment of photoluminescence decay time were caused by the appearance of a plasmon at gold nanoparticles. Keywords: gold nanoparticles, quantum dots, photoluminescence.
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Najafian-Najafabady, Atefeh, Nasim Ebrahimi i Sadeq Vallian. "rs2682818/MiR-618 is a novel marker associated with increased risk of breast cancer in the Iranian population". Archives of Biological Sciences 73, nr 4 (2021): 457–63. http://dx.doi.org/10.2298/abs210808039n.

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The presence of single nucleotide variations in the coding region of micro-RNA (miRNA)-encoding genes plays a significant role in the expression and function of these molecules in oncogenesis and cancer. The association of rs2682818 in miR-618 with increased risk of breast cancer was investigated in the Iranian population. rs2682818/miR-618 was genotyped using amplification-refractory mutation system PCR (ARMS-PCR) in 200 healthy individuals and patients with breast cancer. The data revealed the presence of Hardy-Weinberg equilibrium (HWE) for this marker. The frequency of alleles C and A was 70% and 30%, respectively, in healthy individuals; the frequency of alleles C and A was 44% and 56%, respectively, in patients with breast cancer. Analysis of odd ratios showed that the rs2682818/miR-618 polymorphism is associated with increased probability of breast cancer and is statistically significant (OR=2.97, P=0.0003). The data suggest that rs2682818/miR-618 could be considered a novel marker of increased risk of breast cancer.
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Wysocki, Jan, Minghao Ye, Luise Hassler, Ashwani Kumar Gupta, Yuguo Wang, Vlad Nicoleascu, Glenn Randall, Jason A. Wertheim i Daniel Batlle. "A Novel Soluble ACE2 Variant with Prolonged Duration of Action Neutralizes SARS-CoV-2 Infection in Human Kidney Organoids". Journal of the American Society of Nephrology 32, nr 4 (1.02.2021): 795–803. http://dx.doi.org/10.1681/asn.2020101537.

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BackgroundThere is an urgent need for approaches to prevent and treat SARS-CoV-2 infection. Administration of soluble ACE2 protein acting as a decoy to bind to SARS-CoV-2 should limit viral uptake mediated by binding to membrane-bound full-length ACE2, and further therapeutic benefit should result from ensuring enzymatic ACE2 activity to affected organs in patients with COVID-19.MethodsA short variant of human soluble ACE2 protein consisting of 618 amino acids (hACE2 1–618) was generated and fused with an albumin binding domain (ABD) using an artificial gene encoding ABDCon, with improved albumin binding affinity. Human kidney organoids were used for infectivity studies of SARS-CoV-2 in a BSL-3 facility to examine the neutralizing effect of these novel ACE2 variants.ResultsWhereas plasma ACE2 activity of the naked ACE2 1–618 and ACE2 1–740 lasted about 8 hours, the ACE2 1–618-ABD resulted in substantial activity at 96 hours, and it was still biologically active 3 days after injection. Human kidney organoids express ACE2 and TMPRSS2, and when infected with SARS-CoV-2, our modified long-acting ACE2 variant neutralized infection.ConclusionsThis novel ACE2 1–618-ABD can neutralize SARS-CoV-2 infectivity in human kidney organoids, and its prolonged duration of action should ensure improved efficacy to prevent viral escape and dosing convenience.
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Rozprawy doktorskie na temat "A-618"

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Ng, Mei-pou Mabel, i 吳美寶. "A study on the immigrants from the Korean Peninsula in the Tang Dynasty (618-907)=". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B30479277.

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Ozkan, Cuma. "A comparative analysis| Buddhist Madhyamaka and Daoist Chongxuan (Twofold Mystery) in the early Tang (618-720)". Thesis, The University of Iowa, 2013. http://pqdtopen.proquest.com/#viewpdf?dispub=1540391.

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The interactions between Chinese religions has occupied an enormous amount of scholarly attention in many fields because there have been direct and indirect consequences resulting from the interactions among Buddhism, Daoism, and Confucianism. These religious traditions have obviously influenced each other in many respects such as rituals, doctrines, textual materials, philosophy and so on. Accordingly, I will, in this paper, critically analyze the implications of the interactions between Buddhism and Daoism by examining Twofold Mystery. Since Twofold Mystery is heavily dependent on Madhyamaka Buddhist concepts, this study will, on the one hand, examine the influence of Madhyamaka Buddhism on the development of Twofold Mystery. On the other hand, it will critically survey how Twofold Mystery remained faithful to the Daoist worldview.

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Shum, Ching-man Olivia, i 岑靜雯. "A study of women in the families of government officials in the Tang Dynasty (618-907) =". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B30397881.

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Cho, S. "Death, disease, and Daoism in the Tang (618-907 AD) : a history of Daoist liturgy in medieval China". Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597624.

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This study examines Daoist rituals to deal with the recurring concerns in the medieval Chinese religion: the proper sending-off of the deceased, the avoidance of any malevolent effects associated with death, the search for the salvation of the dead. During the early medieval period, Daoism developed rituals that addressed the religious needs unsatisfied by the Confucian ritual framework. One of such concerns was that the newly dead may bring misfortunes to or harm their own family and neighbours. This is often manifested as diseases in the family. Many of the medical texts compiled during the Tang also show a similar aetiology and recommend ritual methods to drive out the pathogenic agents of the malignant ghosts. Likewise, in the popular religious tradition, the main concern was to prevent any malevolent influences from the dead. While exorcistic rituals were performed to the same end in Daoism too, more emphasis was put on the salvation of the dead. Petitioning rituals and zhai-retreats were observed to save the dead from the sufferings in the netherworld and thereby to eliminate their harmful influences on the living. A comparative analysis of the petitioning ritual and the zhai-retreats shows the historical changes during the Tang in which the latter emerged as the most prevalent form of ritual for the welfare of the living and the salvation of the dead, by inheriting the basic ritual structure of the former. By examining anecdotal literature and excavated materials, this study contextualises the prescriptive contents of the sources in the Daoist canon.
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LIANG, LIAN. "Le costume chinois a l'epoque des tang (618-907). Histoire du costume, de la mode et de la beaute feminine dans les lettres et les arts". Paris 4, 1993. http://www.theses.fr/1993PA040216.

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Le custome, la coiffure, la parure et le maquillage atteignirent les plus hauts sommets a l'epoque des tang (618-907 ap. J. C. ) et temoignent a l'age d'or dans l'histoire du costume chinois. La premiere partie de la these presente une breve retrospective de l'histoire du costume chinois avant la periode tang. La deuxieme partie traite du costume masculin et de ses accessoires. Quant a la troisieme partie, elle concerne le costume feminin, les accessoires, la coiffure, pa parure et le maquillage des femmes de cette epoque. Pour conclure, nous essayons de proposer quelques refelxions sur la civilisation chinoise et le role original et determinant qu'a joue le costume. En annexe, nous parlerons des textiles utilises, des techniques du tissage et de l'impression de tissus. Ce travail est fonde sur les decouvertes archeologiques, les autres sources utilisees sont principalement des peintures, des poesies, et des livres historiques
Costume, hair style, jewellery and make up were at their highest during the tang period and illustrate the golden age of chinese costume. The first part of this thesis presents a short retrospective of chinese costume before the tang dynasty. The second part deals with men's costumes and their accessories. As for the third part, it concerns the women's costumes,the accessories and hair style, the jewellery and women make up during this special period. As a conclusion, we will propose a few ideas on chinese civilization and show the original and ruling part played by the costume. The annexes will mention the types of textiles used at the time, the weaving and printing techniques. This study is based on archaeological discoveries. The other materials are mainly paintings, poems and historical books
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Vicente, Gutiérrez María Pilar. "Crecimiento fetal y del recién nacido: Análisis de la composición corporal y parámetros endocrino- metabólicos al nacimiento y a los 12 meses de vida". Doctoral thesis, Universitat de Barcelona, 2009. http://hdl.handle.net/10803/2494.

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INTRODUCCIÓN: Recientemente se ha demostrado la asociación existente entre el tamaño al nacimiento y la aparición de enfermedades en la vida adulta.
La hipertensión arterial, la diabetes mellitus tipo 2 y la obesidad son más frecuentes en personas que nacieron con peso bajo para su edad gestacional (PBEG).
Los mecanismos que median esta asociación se desconocen, pero parece que el desarrollo de resistencia a la insulina juega un papel fundamental.
Los recién nacidos con PBEG son muy sensibles a la insulina, pero si presentan durante los primeros meses de vida un crecimiento compensador rápido y exagerado, muestran mayor insulinemia basal a los 4 años y mayor adiposidad central a los 6 años de vida.

JUSTIFICACIÓN DEL ESTUDIO: Estudiar las relaciones entre somatometría, composición corporal y parámetros endocrino-metabólicos en recién nacidos sanos puede ser útil para dilucidar los mecanismos subyacentes.

HIPÓTESIS: El grado de crecimiento postnatal en recién nacidos sanos influye en la composición corporal y en los niveles de insulina y adiponectina al año de vida.

OBJETIVOS: 1) Conocer la composición corporal de niños sanos de nuestro medio, a los 10 días y al año de vida. 2) Conocer los niveles de glucosa, insulina y adiponectina en sangre de cordón (SC), y si existe correlación con la antropometría al nacimiento y con la composición corporal a los 10 días de vida. 3) Evaluar la relación entre grado de crecimiento postnatal y porcentaje y distribución de la grasa y niveles de insulina y adiponectina al año de edad.

MATERIAL Y MÉTODOS: Estudio longitudinal prospectivo. Se han incluido 114 recién nacidos sanos de etnia caucásica y edad gestacional ≥ 35 semanas.
Se han cuantificado glucosa, insulina y adiponectina en SC y se ha analizado su composición corporal mediante absorciometría radiológica de doble energía a los 10 días. Al año de vida, se han realizado las mismas pruebas a 92 de estos niños.

RESULTADOS: 1) A los 10 días de vida, las mujeres presentan más masa grasa que los varones (786g vs 567g) y menos masa magra (2840g vs 3070g). Al año, esta diferencia entre sexos persiste (Masa grasa 3594g vs 3281g, masa magra: 6504g vs 7496g). El contenido mineral óseo no varía según el sexo. 2) Parámetros endocrino-metabólicos en SC: La glucosa (Mediana: 73,8 mg/dl) sólo se correlaciona con el tipo de parto. La insulina (Mediana: 5,5 µUI/ml) es mayor en mujeres y muestra correlación positiva con el z-score de peso al nacimiento, el índice ponderal, la adiposidad total, troncal y abdominal. La adiponectina (Media: 34,7 µg/ml) muestra correlación positiva con la adiposidad total y troncal, y negativa con el z-score de longitud al nacimiento. 3) Un mayor incremento de z-score de peso durante el primer año de vida se correlaciona con mayor adiposidad total, troncal y abdominal. No ocurre lo mismo con el incremento de z-score de longitud. Un mayor grado de crecimiento postnatal en peso o longitud en el primer año no se asocia a niveles mayores de insulina ni menores de adiponectina al año de vida.

CONCLUSIONES: 1) En RN sanos de nuestro medio, la masa grasa y la masa magra presentan una clara diferencia en función del sexo, que se mantiene al año de vida. 2) Los niveles de insulina y adiponectina en SC muestran correlación positiva con la adiposidad total y troncal a los 10 días de vida. 3) La adiposidad total, troncal y abdominal es mayor en los lactantes que han presentado un catch-up de peso entre el nacimiento y los 12 meses. 4) Un mayor grado de crecimiento postnatal no se asocia a niveles mayores de insulina ni menores de adiponectina al año de edad.
BACKGROUND: Recent studies suggest an increased frequency of cardiovascular disease and type 2 diabetes in subjects who were small at birth. Fetal undernutrition results in developmental adaptations ("programming") that generate insulin resistance in adulthood. Small for gestational age newborns are highly sensitive to insulin, but after an exaggerated postnatal catch-up they show hyperinsulinemia and increased central adiposity.

HYPOTHESIS: We hypothesised that the degree of postnatal growth in healthy babies is related to body composition and to insulin and adiponectin levels at 1 year of age.
We also explored the relationships between body size, body composition at age 10 days and at 1 year of age, and cord blood glucose, insulin and adiponectin levels.

METHODS: A longitudinal prospective study has been conducted on 114 Caucasian healthy newborn babies (GA≥ 35 weeks). Glucose, insulin and adiponectin have been assessed in cord blood and body composition has been studied by dual energy X-ray absorptiometry (DXA) at 10 days of age. Ninety-two of these babies have undergone the same assessments at age 1 year.

RESULTS: 1) At age 10 days, girls have more fat mass than boys (786g vs 567g, respectively) and less lean mass (2840g vs 3070g, respectively). At age 1 year, these differences persist (fat mass: 3594g vs 3281g, respectively; lean mass: 6504g vs 7496g, respectively); 2) Cord blood parameters: glucose (74 mg/dl) is only related to the type of delivery; insulin (5.5µUI/ml) is higher in girls and positively related to birth weight SDS, ponderal index, and total, truncal and abdominal fat. Adiponectin (34.7µg/ml) shows a positive correlation with total and truncal adiposity and a negative correlation with birth length SDS; 3) A greater increase in weight SDS during the first year is related to higher total, truncal and abdominal fat. A greater postnatal increase in weight and/or length is not associated to higher insulin levels and/or lower adiponectin levels.

CONCLUSIONS: 1) Body composition in healthy newborns is closely related to gender and to insulin and adiponectin levels; 2) Postnatal weight catch-up has an influence on fat amount and distribution, but not on insulin and adiponectin levels at 1 year of age.
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Ferriols, Pérez Elena. "Efecto de una intervención educativa sobre la frecuencia y adecuación de la asistencia a urgencias de las embarazadas de nuestra área". Doctoral thesis, Universitat Autònoma de Barcelona, 2015. http://hdl.handle.net/10803/325158.

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Las visitas inadecuadas a urgencias, que podrían ser resueltas en atención primaria, son frecuentes, y suponen un gasto sanitario que podría reducirse. Los objetivos de nuestro trabajo son: Describir la adecuación de las visitas de las mujeres embarazadas al servicio de urgencias de nuestro centro, tratando de identificar los factores de riesgo para la generación de visitas inadecuadas; elaborar y validar un tríptico informativo sobre los posibles síntomas que pueden aparecer durante el embarazo y qué hacer si aparecen y conocer la eficacia, para reducir las visitas inadecuadas y la frecuentación a urgencias de esta intervención educativa, mediante un estudio de intervención aleatorizado. Se revisaron 1743 visitas a urgencias de obstetricia, clasificándose los motivos de consulta de acuerdo con los tres niveles de adecuación: adecuados, medianamente adecuados e inadecuados. Estos motivos fueron adecuados en los 38,9%, moderadamente adecuados en el 46,7% e inadecuados en el 14,4%. Aquellas pacientes con antecedentes de una muerte perinatal o una gestación de mayor riesgo tendieron a distribuir sus motivos de consulta en los grupos de motivos moderadamente adecuados e inadecuados (marginalmente significativo). Se encontró una tendencia hacia los motivos de consulta más apropiados en embarazos más evolucionados, y menos adecuados en gestaciones más tempranas. El número de fetos a término, pretérmino y abortos previos, se mostraron como variables que no modificaban el nivel de adecuación de forma estadísticamente significativa. Nuestros datos demuestran que la cantidad de visitas inadecuadas y moderadamente adecuadas podría reducirse en un 61% mediante la aplicación de diferentes intervenciones, lo que reduciría de igual modo el gasto sanitario. El tríptico fue validado por cuatro expertos en Obstetricia y por un grupo de 19 gestantes y puérperas. Éste fue repartido en un grupo caso de 209 pacientes embarazadas, aprovechando la primera ecografía de seguimiento y fue comparado a un grupo control de 216 pacientes. No se hallaron diferencias significativas entre los grupos caso y control con respecto a la variable principal Nivel de Adecuación, tampoco en la frecuentación a urgencias entre ambos grupos, siendo de 1,83 visitas de media para ambos grupos. Se hallaron diferencias estadísticamente significativas en el requerimiento de ecografía (mayor en el grupo caso), sin embargo no se hallaron diferencias estadísticamente significativas en la necesidad de ingreso, de sedimento, analítica, ni de registro cardiotocográfico. En análisis a corto plazo no se observaron más diferencias, la herramienta no demostró ser efectiva tampoco a corto plazo. Las visitas inadecuadas tenían lugar con mayor frecuencia por la mañana y por la noche. A mayor edad gestacional se observó una tendencia a generar visitas más adecuadas. En conclusión tras validar un tríptico informativo sobre los posibles síntomas que pueden aparecer durante la gestación y realizar una sencilla y económica intervención educativa sobre una población de gestantes, que ya había demostrado un alto grado de inadecuación en sus motivos de consulta a urgencias, no hemos podido demostrar su eficacia.
Inadequate emergency visits which could be resolved in primary care are frequent. Moreover, they are an unnecessary healthcare service outlay, which could be reduced. There are several aims of this study. First, we would like to describe the adequacy of the emergency visits by pregnant women in our Hospital and to identify the risk factors for an inappropriate visit. Secondly, we intend to develop and validate a leaflet about the symptoms that may occur during pregnancy and instructions for treatment should they appear. Finally, we will analyze the effectiveness of the leaflet to reduce inappropriate visits and attendance to the emergency room by a randomized intervention study. Specifically, out of a sample of 1,743 visits to the Gynecology and Obstetrics emergency, we classified the reasons for consultation according to the three levels of adequacy: adequate, moderately adequate and inadequate. Our findings show consultation motivations were adequate in 38.9% of the cases, moderately adequate in 46.7% and inadequate in 14.4 %. Several factors shaped variations in results. Patients with a history of stillbirth, death child or higher gestational risk tended to distribute their reasons of consultation in groups of moderately adequate and inadequate (marginally significant). We found a trend towards more appropriate reasons for consultation in more developed pregnancies while it was less adequate in the earlier gestations. The number of children at term or preterm and miscarriages are variables that didn´t change the level of adequacy in a statistically significant number. This shows that the amount of inadequate and moderately adequate visits to the emergency department could be reduced by 61 % by implementing different interventions. Therefore, unnecessary expense could be reduced. The leaflet was validated by four obstetricians’ experts and a group of 19 pregnant and puerperal women. The leaflet was committed in a group of 209 pregnant women, during their first ultrasound, and they were compared to a control group of 216 pregnant women. Adequacy level was not different between the case and the control group. No significant differences were found in the primary endpoint: "level of adequacy", between the case group and control group. Every pregnant woman went to emergency room 1.83 times in each group. We found significant differences in ultrasound requirement (the case group required more sonography) but not in hospitalization requirement, urine sediment requirement, "fetal non-stress test" requirement or blood test requirement. No significant differences were found in the short-term analysis; the tool neither proves to be effective in the short term. The inadequacy visits were more frequent during morning and nights. The higher gestational age was, the more appropriate were the visits. In conclusion we validated a leaflet about the symptoms that may occur during pregnancy and used it to make a simple and economic educational intervention in the pregnant woman population. Although we have demonstrated their high level of inappropriate visits to the emergency department, we could not demonstrate efficacy of the educational intervention under these conditions.
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Albareda, Riera Mercè. "Diabetes gestacional: riesgo de desarrollar diabetes mellitus y factores de riesgo cardiovascular a medio plazo". Doctoral thesis, Universitat Autònoma de Barcelona, 2001. http://hdl.handle.net/10803/4377.

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A pesar de que el concepto de diabetes gestacional (DMG) como lo entendemos actualmente data de 1979, las primeras referencias que nos constan son del siglo XIX (Bennewitz 1824, Duncan 1882), y antes de 1979 ya se hab'an publicado estudios de cribaje, diagnóstico y mortalidad perinatal (Hoet 1954, Wilkerson 1957, O'Sullivan y Mahan 1964, Pedersen 1967, Mestman 1971). En la actualidad, la DMG se define como la intolerancia a la glucosa de gravedad variable con inicio o primer reconocimiento durante la gestación. Este concepto fue incluido en la clasificación diagnóstica de la diabetes mellitus (DM) por el National Diabetes Data Group (NDDG) en 1979 (NDDMG 1979), y por la Organización Mundial de la Salud (OMS) en 1980 (WHO 1985). En el primer Workshop sobre DMG en 1980 (ADA 1980) ya se adoptó dicha ón, y en el segundo, se añadió el concepto de que debe aplicarse independientemente de si es necesario el tratamiento insulínico o de si persiste la alteración metabólica en el posparto (ADA 1985). Estas consideraciones se han mantenido también en el tercer y cuarto Workshops. Ello no obvia la necesidad de reclasificar la tolerancia a la glucosa en el posparto en todas las mujeres afectas.
La prevalencia de la DMG en diferentes poblaciones oscila entre el 0,15 y el 15% (tabla 1), interpretándose las diferencias por variaciones geográficas y étnicas (King 1998) además de la influencia de la utilización de diferentes métodos de cribaje y diagnóstico (Oats 1988, Dornhorst 1990, O'Sullivan 1991, Schwartz 1999). Así, en un grupo de 8857 mujeres gestantes, el diagnóstico de DMG se realizó en el 3,21% utilizando los criterios de NDDG y en el 4,95% según los de Carpenter y Counstan (Schwartz 1999). El riesgo de DMG aumenta con la edad materna, el sobrepeso, la paridad, los antecedentes familiares de DM y el antecedente de resultados adversos en embarazos previos, observándose además un aumento de prevalencia en los últimos años (King 1998).
Esta entidad se asocia a un aumento de la morbilidad materna y fetal tanto en el período perinatal como a largo plazo. Se ha descrito un mayor riesgo de preeclampsia, hidramnios y parto por cesárea, además de un mayor riesgo en el feto de macrosomía, traumatismo obstétrico, síndrome de distrés respiratorio y alteraciones bioquímicas transitorias (O'Sullivan 1973, Gyves 1977, Kitzmiller 1978, Widness 1985). La DMG también se acompaña de un mayor riesgo de diabetes DMNID a largo plazo en la madre (Mestman 1988, O'Sullivan 1991) y de diabetes, obesidad y alteración del desarrollo intelectual y psicomotor en sus hijos (Freinkel 1980, Pettitt 1991, Silverman 1998). Dado que tanto las repercusiones perinatales como a largo plazo se han asociado a un ambiente metabólico intrauterino adverso (Pettitt 1993, De Veciana 1995, Silverman 1998) es importante tanto el diagnóstico como su tratamiento para prevenirlas.
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Lau, Cheung-cheung. "A study of livelihood and city policy in Chang'an, the capital of Tang dynasty (618-907) Tang dai shou du Changan de ju min sheng ji yu cheng shi zheng ce yan jiu /". Click to view the E-thesis via HKUTO, 2005. http://sunzi.lib.hku.hk/hkuto/record/Bibno.

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Lynn, F. A. "The value of a third trimester ultrasound scan in low-risk pregnancy; a discrete choice approach". Thesis, Queen's University Belfast, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.517102.

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Książki na temat "A-618"

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Copyright Paperback Collection (Library of Congress), red. Should've Been a Cowboy: Sons of Chance - 4, Harlequin Blaze - 618. Toronto: Harlequin, 2011.

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Curtis, D. A most secret squadron: The story of no. 618 squadron and its special detachment, Royal Air Force. Wimborne: Skitten Books, 1995.

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Power, Jenny. The Austrian Arbitration Act: A Practitioner's guide to sections 577-618 of the Austrian Code of Civil Procedure. Wien: Manz, 2006.

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United States. Congress. Senate. Committee on Foreign Relations. A bill to promote the strengthening of the private sector in Egypt and Tunisia: Report (to accompany S. 618). Washington, D.C: U.S. G.P.O., 2011.

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Association, International Air Transport, red. Dangerous goods regulations: (IATA resolution 618, attachment "A") : effective from 1 January through 31 December 2005 : quick reference guide. Montréal: International Air Transport Association, 2004.

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Quirós, Carlos Barragán. Procesos disciplinarios ante el ministerio de educación: Análisis, procedimientos y comentarios a las normas educativas, y cuestionamiento al Decreto Ejecutivo 618 de 1952. Panamá: Cultural Portobelo, 2012.

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United States. Congress. Senate. Committee on Indian Affairs (1993- ). Providing for the use and distribution of the funds awarded to the Western Shoshone identifiable group under Indian Claims Commission docket numbers 326-A-1, 326-A-3, 326-K, and for other purposes: Report (to accompany S. 618). [Washington, D.C: U.S. G.P.O., 2003.

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United States. Congress. Senate. Committee on Indian Affairs (1993- ). Providing for the use and distribution of the funds awarded to the Western Shoshone identifiable group under Indian Claims Commission docket numbers 326-A-1, 326-A-3, 326-K, and for other purposes: Report (to accompany S. 618). [Washington, D.C: U.S. G.P.O., 2003.

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Providing for the use and distribution of the funds awarded to the Western Shoshone identifiable group under Indian Claims Commission docket numbers 326-A-1, 326-A-3, 326-K, and for other purposes: Report (to accompany S. 618). [Washington, D.C: U.S. G.P.O., 2003.

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Publishing, A+U. A+u 22 : 03, 618 : Feature: Colombia. Shinkenchiku-Sha, 2022.

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Części książek na temat "A-618"

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Xiao, Jun, i Maofei Geng. "Analysis and Treatment of Gas Pulsation in the Pipeline of a Hydrogen Diaphragm Compressor". W Proceedings of the 10th Hydrogen Technology Convention, Volume 1, 1–14. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-8631-6_1.

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AbstractBased on the plane wave theory and the transfer matrix method, the modeling, calculation and analysis of gas pulsation in a complex pipeline system of a hydrogen diaphragm compressor were carried out. The calculations show that the gas pulsations of the intake and exhaust pipelines of the cylinder gradually attenuate along the pipeline upstream and downstream, and the gas pulsation of the exhaust pipeline of the second stage cylinder is larger. The gas pulsations of the exhaust pipelines of the first and second stage cylinders are significantly higher than the limit values of API 618. From the perspective of pulsation control, an attempt was made to add orifice plates at appropriate positions of the pipeline to reduce the pulsation amplitude. The trial calculations show that the added orifice plate can effectively reduce the maximum gas pulsation of the pipeline, and can provide a useful reference for the treatment of gas pulsation.
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Walton, André P. "Creativity and a Human Dichotomy: Individual or Part of a Team?" W Creativity in the Twenty First Century, 85–102. Singapore: Springer Singapore, 2015. http://dx.doi.org/10.1007/978-981-287-618-8_6.

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Dorniak-Wall, Kristina. "A Review of Integrated Approaches to the Study of Creativity: A Proposal for a Systems Framework for Creativity". W Creativity in the Twenty First Century, 33–52. Singapore: Springer Singapore, 2015. http://dx.doi.org/10.1007/978-981-287-618-8_3.

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Karadag, Zekeriya, i Douglas McDougall. "Geogebra as a Cognitive Tool". W Model-Centered Learning, 169–81. Rotterdam: SensePublishers, 2011. http://dx.doi.org/10.1007/978-94-6091-618-2_12.

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Faggiano, Eleonora, i Palmira Ronchi. "Geogebra as a Methodological Resource". W Model-Centered Learning, 183–89. Rotterdam: SensePublishers, 2011. http://dx.doi.org/10.1007/978-94-6091-618-2_13.

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Cody, Delphine, i Timothy Gordon. "TRB Workshop on Driver Models: A Step Towards a Comprehensive Model of Driving?" W Modelling Driver Behaviour in Automotive Environments, 26–42. London: Springer London, 2007. http://dx.doi.org/10.1007/978-1-84628-618-6_2.

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Baumann, M., i J. F. Krems. "Situation Awareness and Driving: A Cognitive Model". W Modelling Driver Behaviour in Automotive Environments, 253–65. London: Springer London, 2007. http://dx.doi.org/10.1007/978-1-84628-618-6_14.

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Mousoulides, Nicholas G. "Geogebra as a Conceptual Tool for Modeling Real World Problems". W Model-Centered Learning, 105–18. Rotterdam: SensePublishers, 2011. http://dx.doi.org/10.1007/978-94-6091-618-2_8.

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Engström, Johan, i Erik Hollnagel. "A General Conceptual Framework for Modelling Behavioural Effects of Driver Support Functions". W Modelling Driver Behaviour in Automotive Environments, 61–84. London: Springer London, 2007. http://dx.doi.org/10.1007/978-1-84628-618-6_4.

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Zhou, Chunfang, i Paola Valero. "A Comparison of Creativity in Project Groups in Science and Engineering Education in Denmark and China". W Creativity in the Twenty First Century, 133–51. Singapore: Springer Singapore, 2015. http://dx.doi.org/10.1007/978-981-287-618-8_9.

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Streszczenia konferencji na temat "A-618"

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Löndahl, Jakob, Madeleine Petersson Sjögren, Laura Aaltonen, Jonas Jakobsson, Hanna Nicklasson, Jenny Rissler i Per Wollmer. "Measurement of peripheral airspaces by nanoparticles in a group of 618 subjects". W ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.3758.

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Daudi, Ligat, Ligat Luder, Ligat Spitzer-Shohat i Mary Rudolf. "618 Keeping our children safe: piloting a hospital-based home-visitation program". W Royal College of Paediatrics and Child Health, Abstracts of the RCPCH Conference–Online, 15 June 2021–17 June 2021. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2021. http://dx.doi.org/10.1136/archdischild-2021-rcpch.104.

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Ding, Leibo, John W. Cooper, Aboubakar Traore, Gilbert R. Smith i James J. Butler. "Characterization of a radiometric monitoring system for NASA code 618's SIRCUS-G". W SPIE Optical Engineering + Applications, redaktorzy James J. Butler, Xiaoxiong (Jack) Xiong i Xingfa Gu. SPIE, 2013. http://dx.doi.org/10.1117/12.2026982.

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Howes, Brian C., i Shelley D. Greenfield. "Guidelines in Pulsation Studies for Reciprocating Compressors". W 2002 4th International Pipeline Conference. ASMEDC, 2002. http://dx.doi.org/10.1115/ipc2002-27421.

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While new gas compression in pipeline service tends to be dominated by centrifugal machines, reciprocating compressors still have a significant place in the industry. Specific dynamic design is required to ensure reliable and efficient operation of all reciprocating compressor installations. This requirement is particularly significant in pipeline installations, because the compressor is intended to be in service for many years, and because high efficiency is important for economic reasons. It is widely recognized that the design of these types of installations should include a “pulsation study”. A pulsation study involves analysis of the proposed installation to predict pulsation, vibration, and stress levels. Further, a pulsation vibration control scheme is developed as part of the overall design. The objective is to ensure that predicted pulsation and vibration levels meet guidelines while limiting associated pressure drops and horsepower losses to acceptable levels. Various guidelines have been used in these studies, but the most commonly used standards are in API 618. While this standard was not originally intended for pipeline service, in reality it represents the best design standard available for high specification reciprocating compressor installations in any application. Recently, work has been done to upgrade the API 618 design standard. One of the changes in the proposed new 5th edition is the addition of unbalanced force guidelines to the existing pressure pulsation guidelines. Much discussion occurred regarding the need for and the advisability of making the addition. Real examples show designs in which a reduction of pressure pulsation is accompanied by an increase in unbalanced forces, illustrating the need for an unbalanced force guideline. It is also shown that problems can occur due to unbalanced forces in parts of the piping system not currently addressed by the pulsation guidelines in API 618. The paper compares the current 4th Edition versus the draft 5th Edition. Comments are made on the applicability of the various guidelines. While API 618 is the best available design document, the addition of force guidelines will help API 618 do a better job for industry.
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Payne, Susan, Tyler Foley, Cheri Pasch, Alexander Yueh, Demetra Korkos, Dana Van De Hey, Linda Clipson i Dustin Deming. "Abstract 618: Dual PI3K/mTOR inhibition as a treatment strategy for PIK3CA and APC mutant colorectal cancers". W Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-618.

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Xianfeng Yang, Tao Jiang i Tianzhu Han. "Research on a Simplified Air-Ground propagation model based on ITU-R P.618 and P.676". W 2016 Progress in Electromagnetic Research Symposium (PIERS). IEEE, 2016. http://dx.doi.org/10.1109/piers.2016.7735657.

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Kusyk, Kinga Maria, Anna Abacjew-Chmylko i Dariusz Wydra. "618 Clear cell carcinoma arising in caesarean section scar: a case of 52-year-old woman and literature review". W ESGO 2024 Congress Abstracts. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/ijgc-2024-esgo.508.

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Wang, Guan, Cheng Chen, Jinwang Wei, Angela Wu, Chun Dai, Xiaoman Xu, Xin Cai i Qiang Xu. "Abstract 618: Application of clinical whole-exome sequencing as a predictor of clinical benefit of PD1/PDL1 blockade in a prospective study of advanced cancer patients". W Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-618.

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Fork, R. L., C. H. Brito Cruz, W. H. Knox i Charles V. Shank. "Ultrafast dynamics of dyes using 10-fs pulses". W OSA Annual Meeting. Washington, D.C.: Optica Publishing Group, 1986. http://dx.doi.org/10.1364/oam.1986.thm4.

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We report on the dynamics of nonequilibrium distributions of dye molecules, such as, Nile Blue, Cresyl Violet, sulforhodamine 640, and rhodamine B, excited by pump pulses of 65-fs duration and probed by pulses compressed to durations of 10 fs. We examine a spectral region centered at the pump wavelength, 618 nm, and ranging from 570 to 670 nm. Differential absorption spectra are taken at intervals of 25 fs following the initial excitation of the dye. We observe optically induced changes which reach equilibrium within a few hundred femtoseconds following excitation. Of special interest is hole burning at the pump wave-length as well as bleaching of replica holes at energies shifted from the pump energy by a vibrational quantum energy. We also observe transient excited state absorption in near-infrared dyes due to pump-induced nonequilibrium population of the vibrational levels of the upper electronic state and transient-induced transmission in dyes such as rhodamine B where our 618-nm pump pulse lies below the absorption edge of the dye. We discuss the relationship of these optically induced dynamics with ultrashort pulse formation in lasers.
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Golding, Michael A., Fareha Nishat, Kaitlyn A. Merrill, Ramandeep Kaur, Jennifer Stinson, Jennifer LP Protudjer, Roberta L. Woodgate i in. "618 Lived educational experience of young adults with childhood- and adult-onset systemic lupus erythematosus: a multi-center Canadian qualitative study". W Lupus 21st Century 2023 Abstracts, September 27–30, Naples, Florida. Lupus Foundation of America, 2024. http://dx.doi.org/10.1136/lupus-2023-lupus21century.47.

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Raporty organizacyjne na temat "A-618"

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Posso, Christian, Jorge Tamayo, Arlen Guarin i Estefania Saravia. Luck of the Draw: The Causal Effect of Physicians on Birth Outcomes. Banco de la República, kwiecień 2024. http://dx.doi.org/10.32468/be.1269.

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Identifying the impact of physicians on health outcomes is a challenging task due to the nonrandom sorting between physicians, hospitals, and patients. We overcome this challenge by exploiting a Colombian government program that randomly assigned 2,126 physicians to 618 small hospitals. We estimate the impact on the 256,806 children whose mothers received care in those hospitals during their pregnancy, using administrative data from the program, hospitals’ vital statistics records, and physicians’ records from mandatory health-specific graduation exams. We find that more-skilled physicians improve health at birth outcomes. That is, being assigned a physician with a one standard deviation higher performance in the health graduation exam scores decreases the probability of giving birth to an unhealthy baby by 6.31 percent. We present evidence that an underlying mechanism includes improving the targeting of care toward the more vulnerable mothers.
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Ren, Weiju. Development of a Controlled Material Specification for Alloy 617 for Nuclear Applications. Office of Scientific and Technical Information (OSTI), maj 2005. http://dx.doi.org/10.2172/1034357.

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Nelson, Kenneth Day. Polarization of Lambda(0) inclusively produced by a 610-GeV/c Sigma- beam. Office of Scientific and Technical Information (OSTI), styczeń 1999. http://dx.doi.org/10.2172/1421506.

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Korinko, P. S. High temperature environmental interactions of Inconel 617: A paper study for the TEF. Office of Scientific and Technical Information (OSTI), czerwiec 2000. http://dx.doi.org/10.2172/756740.

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Dietzmann i Urban. L51565 Emissions Data for Stationary Engines in the Natural Gas Pipeline Transmission Industry. Chantilly, Virginia: Pipeline Research Council International, Inc. (PRCI), styczeń 1988. http://dx.doi.org/10.55274/r0010130.

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In 1972, PRCI Project PR-15-61 was initiated to measure exhaust emissions from stationary reciprocating gas engines and gas turbines used in natural gas compressor stations. Emission rates of oxides of nitrogen (NOx), hydrocarbons (HC), and carbon monoxide (CO) were measured from 59 reciprocating gas engines and nine gas turbines. During and subsequent to 1972, the PRCI laboratories and various PRCI member companies conducted emissions measurements. In 1978, PRCI Project PR-15-92 was initiated to conduct additional emissions measurements. That project involved 55 reciprocating gas engines and 11 gas turbines. All of those data were included in the May 1980 revision to the compilation of emissions data. Subsequent to the May 1980 revision, additional emissions measurements were conducted under PRCI Projects PR-15425 and PR-15-613, and emissions data were obtained from gas transmission companies and gas engine manufacturers in PR-15-613. These additional data are included in this 1988 reissue of the compilation. The emissions data presented in this data book have been obtained from projects conducted or sponsored by the Pipeline Research Committee of the Pipeline Research Council International (PRCI), individual PRCI member companies, or gas engine manufacturers. Data included are from in-use reciprocating engines and gas turbines that have been in-service for anywhere from less than a year to one or more decades. These data are generally presented as received. Editing has been limited to omitting data for entire tests only where the data are obviously in error and to identifying specific erroneous or questionable items within a test.
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Palacio Sanchez, Alejandro. La incidencia de la ley 617 en las finanzas de los municipios de Antioquia: vigencias de 2017 a 2021. Contraloría General de Antioquia, styczeń 2023. http://dx.doi.org/10.58373/obscga.009.

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La ley 617 del año 2000 obliga a los municipios al cumplimiento de los límites de gastos de funcionamiento con los ingresos corrientes de libre destinación, estos se incrementan año a año con el propósito de confrontar los gastos y el riesgo de incumplir. El objeto de este artículo busca determinar si la ley 617 contribuyó al mejoramiento de los ingresos y a la austeridad de los gastos de funcionamiento en los municipios de Antioquia en las vigencias 2017 a 2021, de acuerdo con el reporte de ingresos y egresos y a la evaluación realizada por la Contraloría General de Antioquia y el Departamento Administrativo de Planeación de la Gobernación de Antioquia. De igual manera, se analizó a la ley 617 considerando el aumento de los ingresos de los municipios, debido a que la mayoría ha incrementado los recursos del “Sistema General de Participaciones” (SGP) por eficiencia fiscal y eficiencia administrativa. La investigación se ejecutó con información de la Gobernación de Antioquia y se enfocó en temas de ingresos corrientes de libre destinación. Los gastos de funcionamiento se deflactaron a la vigencia 2017; se analizaron los incrementos y depreciaciones de los ingresos y gastos de funcionamiento; y se identificó cuáles incumplieron la ley 617 con el fin de determinar si han implementado estrategias. A partir de los resultados obtenidos, se logró evidenciar que la ley 617 efectivamente alcanzó su cometido en garantizar que los municipios incrementaron sus ingresos corrientes de libre destinación.
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Zarr, Robert R., i Betty A. Licitra. Calibration at 24[degrees]C of a heat-flow-meter apparatus having 610 mm square plates. Gaithersburg, MD: National Institute of Standards and Technology, 1991. http://dx.doi.org/10.6028/nist.ir.4539.

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Sheets, Colton. PR-201-154500-R01 Composite Repair Load Transfer Study. Chantilly, Virginia: Pipeline Research Council International, Inc. (PRCI), marzec 2018. http://dx.doi.org/10.55274/r0011468.

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The objective of the PRCI MATR-3-11 Composite Repair Load Transfer Study was to evaluate the effect of internal pipe pressure during installation of composite reinforcement systems. Historically, there has been little work evaluating the effect of internal pressure during installation, even though almost all composite installations on transmission pipelines are performed with internal pressure present in the pipe. The focus of this work was specifically limited to reinforcement of pipelines containing simulated corrosion anomalies. Five composite repair technologies from four composite manufacturers were evaluated in this study including: � Western Specialties Ultra-Wrap (E-glass/epoxy) � Western Specialties Composi-Sleeve (steel sleeve with E-glass overwrap) � Citadel (carbon fiber/epoxy) � Furmanite (carbon fiber/epoxy) � NRI Steel Wrap (high-modulus carbon fiber/epoxy) This study used full-scale testing to analyze the load transfer between the composite repair and pipe with internal pressure present during installation and whether this condition impacts the reinforcement provided by the composite repair system. The anomaly configuration evaluated in this study was a machined corrosion defect simulating 50% wall loss in 12.75-inch x 0.375-inch, Grade X42 pipe material. For safety, internal pressure during installation was limited to 50% SMYS (1,236 psig) for the corrosion samples. The composite repairs for the corrosion defects were installed at internal pressure levels of 0 psig, 25% SMYS (618 psig), and 50% SMYS (1,236 psig). Following repair installation, the reinforced full-scale samples were burst tested or pressure cycled to failure to evaluate the repair's performance. Results indicated that, in general, internal pressure during installation did not significantly impact the ability of the composite systems to reinforce the corrosion anomalies evaluated in this study when installed at or below 50% SMYS. Installation pressures up to 50% SMYS had no noticeable effect on the burst pressure of the corroded sample composite repairs, and the burst pressure of all repairs were equivalent to pressure levels for an unreinforced, undamaged pipe. Also, all repairs failed at approximately the same average burst pressure, regardless of installation pressure. Furthermore, installation pressures up to 50% SMYS had little or no noticeable effect on the fatigue life of reinforced corrosion samples; all sample repairs reached the target runout of 250,000 cycles. Observations from the burst testing suggested that loads from the corroded region were not transferred to the composite repair until the corroded region began to yield, regardless of the pressure at which the composite was installed (applicable for installation pressures at or below 50% SMYS and a corrosion depth of 50%). The results and findings of this study provide valuable information to the pipeline industry for addressing an issue of significant interest for many years, and one not previously addressed in a comprehensive manner via full-scale testing. An important observation from this study is that the performance of composite repairs made on corrosion defects does not appear to be appreciably reduced when internal pressures up to 50% SMYS are present during installation.
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Bennett, W. J., i Jr. Intensive Cultural Resources Survey Ditch 61 Extension Poinsett County, Arkansas: A Negative Finding. Fort Belvoir, VA: Defense Technical Information Center, styczeń 1988. http://dx.doi.org/10.21236/ada263147.

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Popov, Nikolay T., Veselin D. Petrov, Danail S. Minchev, Ivan Minkov i Tihomir I. Valchev. Comparative Expression Analysis of miR‒619‒5p in Serum and PBMCs as a Promising Candidate Biomarker for Autism Spectrum Disorder. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, kwiecień 2021. http://dx.doi.org/10.7546/crabs.2021.04.08.

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