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Artykuły w czasopismach na temat "869.3/3"

1

Brozović, Marina, i Robert A. Jacobson. "Post-new-horizons Orbits and Masses for the Satellites of Pluto". Astronomical Journal 167, nr 6 (8.05.2024): 256. http://dx.doi.org/10.3847/1538-3881/ad39f0.

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Abstract We report on ephemerides for the satellites of Pluto based on the large set of astrometric measurements. Our orbit fit yielded the following masses with 1σ uncertainties: GM Pluto = 869.3 ± 0.4 km3 s−2, GM Charon = 106.1 ± 0.3 km3 s−2, GM Nix = 1.50 ± 0.52 × 10−3 km3 s−2, GM Hydra = 2.01 ± 0.27 × 10−3 km3 s−2, corresponding to the densities of ρ Pluto = 1.853 ± 0.004 g cm−3, ρ Charon = 1.705 ± 0.006 g cm−3, ρ Nix = 0.88 ± 0.31 g cm−3, and ρ Hydra = 1.21 ± 0.19 g cm−3. Masses of Kerberos and Styx remain unconstrained, and it is unlikely that we will be able to measure them even if we obtain abundant 1 mas precision astrometry during the next 20 yr. We summarize the results of orbit integration in terms of osculating and precessing ellipse model mean elements. All satellites reside in near-circular orbits, and Kerberos and Styx have 0.4 deg and 0.3 deg inclinations with respect to Charon’s orbit plane. The nodal regression periods for Kerberos and Hydra are ∼9 and ∼14 yr respectively. We found that Charon’s orbit pole can be approximated as: R.A. = 133.0073 + 0.0036T deg, and decl. = –6.2449 + 2.5 × 10−5 T deg, where T is Julian centuries from the epoch J2000, based on 5000 yr of orbit integration.
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Mühlenbruch, G., J. E. Wildberger, R. Koos, M. Das, C. Thomas, K. Ruhl, M. Niethammer i in. "Calcium scoring of aortic valve calcification in aortic valve stenosis with a multislice computed tomography scanner: non-enhanced versus contrast-enhanced studies". Acta Radiologica 46, nr 6 (październik 2005): 561–66. http://dx.doi.org/10.1080/02841850510021698.

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Purpose: Previous studies have shown a positive correlation between amount of aortic valve calcification (AVC) and degree of aortic valve stenosis (AVS). We have investigated whether calcium scoring of AVC from contrast-enhanced images is reliable. Material and Methods: Nineteen patients with suspected AVS underwent retrospectively ECG-gated multislice computed tomography (MSCT). Standardized scan protocols were applied prior to (120 KV, 133 mAseff) and after (120 KV, 500 mAseff) the administration of non-ionic contrast material. Image reconstruction was performed at 60% of the RR interval (slice thickness 3 mm, reconstruction increment 2 mm). AVC was quantified using Agatston score and calcium mass. The number of lesions was calculated. All non-enhanced images were scored using thresholds of 130 HU and 350 HU. Contrast-enhanced images were assessed with a threshold of 350 HU exclusively. Results: Fifteen patients with AVCs were included in the statistical analysis. The mean Agatston score (calcium mass) in non-enhanced images was 2888.4±2844.4 (694.2 mg±869.3 mg). Altering the threshold from 130 HU to 350 HU led to a 58.2% (30.5%) decrease in the AVC score ( P values <0.001). Contrast-enhanced images showed an increased Agatston score (calcium mass) of 56.2% (33.5%) compared to non-enhanced images ( P values <0.05) with the same threshold of 350 HU. Conclusion: Quantification of AVC from contrast-enhanced images is not reliable, as contrast material simulates calcification.
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Mahon, F., G. Etienne, S. Picard, K. Titier, G. Marit, B. Begaud, J. Reiffers, N. Moore i M. Molimard. "Trough plasma imatinib concentrations are associated with responses to standard-dose imatinib in chronic myeloid leukemia and could improve its clinical management". Journal of Clinical Oncology 25, nr 18_suppl (20.06.2007): 7027. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.7027.

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7027 Background: Variable responses to imatinib in the treatment of myelogenous leukemia (CML) are incompletely understood. Previous studies focused on cellular mechanisms of resistance to imatinib. Another hypothesis for variable response lies in pharmacokinetic variability that may reduce drug exposure in patients receiving imatinib. Methods: Using high- performance liquid chromatography-tandem mass spectrometry, we assessed trough plasma imatinib concentrations at steady state (Cmin) in more than 150 CML patients. Major molecular response (MMR) was defined as a 3 logarithm reduction of BCR-ABL transcripts, quantified from peripheral blood using Q-RTPCR. In addition, suboptimal response criteria defined by the European Leukemianet were used to increase doses of imatinib. Results: i) we assessed Cmin in 85 CML patients and demonstated a correlation with imatinib doses (median values 813, 1,135, 1,709 ng/ml for respectively 300,400, 600 mg/day). ii) for 68 patients after at least one year's treatment mean Cmin were significantly higher in the group with MMR (34 patients) than in the group without (1,452.1±649.1 ng per milliliter vs. 869.3±427.5 ng per milliliter, P<0.001) whereas there was no difference in the imatinib daily dose. For Cmin and their discrimination potential for MMR, the area under receiver-operating characteristic curve was 0.775, with best sensitivity (76.5 percent) and specificity (70.6 percent) at a plasma threshold of 1,002 ng per milliliter. iii) dose escalation of imatinid, 400mg up to 600mg was proposed in 8 patients in suboptimal response (3 according to cytogenetic criteria and 5 according to molecular criteria). The median Cmin increase from 573 ng/ml [181–1,376] to 1,139 ng/ml [733–2,262] and 5 patients had a cytogenetic (n=3) or a molecular (n=2) response. Conclusions: Monitoring of imatinib plasma levels could be very useful for the management of CML patients, or should at least be checked in the case of treatment failure or suboptimal response or in patients nonadherent with imatinib or with a drug-drug interaction suspicion. No significant financial relationships to disclose.
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Picard, Stephane, Karine Titier, Gabriel Etienne, Regis Lassalle, Gerald Marit, Josy Reiffers, Bernard Begaud, Nicholas Moore, Mathieu Molimard i Francois-Xavier Mahon. "Trough Plasma Imatinib Concentrations Are Associated with Both Cytogenetic and Molecular Responses to Standard-Dose Imatinib in Chronic Myeloid Leukemia." Blood 108, nr 11 (1.11.2006): 2141. http://dx.doi.org/10.1182/blood.v108.11.2141.2141.

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Abstract BACKGROUND Variable responses to imatinib, in the treatment of chronic myeloid leukemia (CML), are incompletely understood. Previous studies focused on cellular mechanisms of resistance to imatinib. Another hypothesis for variable response lies in pharmacokinetic variability that may reduce drug exposure in patients receiving imatinib. METHODS Using high-performance liquid chromatography-tandem mass spectrometry, we assessed trough plasma imatinib concentrations in CML patients who responded or not to standard-dose imatinib, after at least one year’s treatment. Complete cytogenetic response (CCR) was defined as 0 percent Philadelphia-chromosome-positive cells in bone marrow. Major molecular response (MMR) was defined as a 3 logarithm reduction of BCR-ABL transcripts, quantified from peripheral blood using real-time quantitative reverse-transcriptase polymerase chain reaction. RESULTS Sixty-eight patients were included. Mean trough plasma imatinib concentrations were significantly higher in the group with CCR (56 patients) than in the group without (P=0.02). Mean (±SD) trough plasma imatinib concentrations were significantly higher in the group with MMR (34 patients) than in the group without (1452.1±649.1 ng per milliliter vs. 869.3±427.5 ng per milliliter, P<0.001) whereas there was no difference in the imatinib daily dose. For trough plasma imatinib concentrations and their discrimination potential for MMR, the area under receiver-operating characteristic curve was 0.775, with best sensitivity (76.5 percent) and specificity (70.6 percent) at a plasma threshold of 1002 ng per milliliter. CONCLUSIONS Monitoring of plasma imatinib concentrations may become part of standard management of CML patients, or should at the very least be checked in the case of treatment failure or suboptimal response.
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Chaves, André Silva, Olívia de Andrade Raponi, Maria Virginia Gelfuso i Daniel Thomazini. "Pure and Doped SrTiO3 Powders Obtained by Ultrasonic Synthesis". Materials Science Forum 869 (sierpień 2016): 3–7. http://dx.doi.org/10.4028/www.scientific.net/msf.869.3.

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Thermoelectric ceramics are those capable of converting thermal into electricity energy by the Seebeck effect. The non-conventional synthesis of ceramic powders and the doping of these powders with rare earth elements are factors that can improve the efficiency in energy conversion. The objective of this work was to synthesize and analyze pure and doped SrTiO3 powders by solid state reaction (SSR) and ultrasonic synthesis (USS). The precursors of SSR were: strontium carbonate (SrCO3), titanium oxide (TiO2) and lanthanum and neodymium oxide (La2O3 and Nd2O3). They were mixed in a ball mill for 3.5h in stoichiometric ratio to obtain SrTiO3 (STO), Sr0.96La0.04TiO3 (STO-04La), Sr0.96Nd0.04TiO3 (STO-04Nd) and Sr0.96La0.02Nd0.02TiO3 (STO-02La02Nd). The powder mixtures were calcined at 1000°C in a conventional oven for 2h. The USS powders were produced by solubilization of Ti (C4H9O)4 and SrCO3 in an HNO3 aqueous solution. The solution was precipitated with NH4OH and, then, this powder was dried at 70°C for 24h, in air. The dried powder was added to a solution of KOH and subjected to ultrasound irradiation. The same procedure was followed for the synthesis of USS doped powders, STO-04La, STO-04Nd, and STO-02La02Nd powders using as dopant lanthanum and neodymium oxides. The powders were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and crystallite sizes were calculated by the Scherrer equation to evaluate the differences on structural and microstructural properties.
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Arif, Nayab, Zhao-Xu Wang, Yan-Tao Wang, Yi-Chuan Dou, Kui Li, Shi-Quan Liu i Fu-Tian Liu. "Design of earth-abundant Z-scheme g-C3N4/rGO/FeOOH ternary heterojunctions with excellent photocatalytic activity". CrystEngComm 23, nr 9 (2021): 1991–98. http://dx.doi.org/10.1039/d1ce00045d.

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A ternary Z-scheme g-C3N4/rGO/FeOOH heterostructure photocatalyst for H2 production was designed and fabricated, which exhibited photocatalytic H2 production of 124.9 and 869.8 μmol h−1 g−1 under visible and UV-Vis light irradiation, respectively.
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Zein, Yusuf Muhammad, Anil Kumar Anal, Didik Prasetyoko i Imroatul Qoniah. "Biodiesel Production from Waste Palm Oil Catalyzed by Hierarchical ZSM-5 Supported Calcium Oxide". Indonesian Journal of Chemistry 16, nr 1 (15.03.2018): 98. http://dx.doi.org/10.22146/ijc.21184.

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Biodiesel production from waste palm oil catalyzed by hierarchical ZSM-5 supported calcium oxide was studied. The activity of CaO increased after supported on h-ZSM-5 resulting an increase in conversion from 93.17% to 95.40%. A maximum conversion of 95.40% was achieved at 6 h reaction time, 3 wt.% catalyst amount, 12:1 methanol to oil molar ratio and 65 °C reaction temperature. The waste palm oil showed a high potential as a feedstock in biodiesel production in which there was no significant different in the conversion of fresh and waste palm oil. The properties of the obtained biodiesel required the limits of biodiesel specification according to ASTM D6751-08 and EN 14214 with the methyl ester content of 97.18%, the acid value of 0.24 mg KOH/g, the kinematic viscosity of 4.64 cSt and the density of 869.9 kg/m3.
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Navarro, Marco, Claudio Guillen i Leónidas Limache. "Valoración económica del Área de Conservación Regional Vilacota Maure: Servicios ecosistémicos priorizados al extremo sur del Perú". Ciencia & Desarrollo, nr 27 (30.12.2020): 65–77. http://dx.doi.org/10.33326/26176033.2020.27.998.

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A pesar de la importancia que tienen los bienes y servicios ecosistémicos en la economía mundial, en la gestión del Área de Conservación Regional Vilacota Maure en el departamento de Tacna aún se mantienen desfasados paradigmas de uso irracional de recursos y de sobreexplotación, manifestándose en grandes presiones y amenazas a los ecosistemas, contrarias a sus objetivos de conservación. Es por ello que en una reunión de expertos (focus group), se priorizó valorizar económicamente a tres servicios ecosistémicos que representan mejor su importancia: provisión de recurso hídrico, el secuestro de carbono y provisión de recursos genéticos o forraje ganadero. Para la determinación de la valoración económica de estos servicios se aplicó el método preferencias reveladas y de precios de mercado, resultando $ 1 749 548.65, $ 454 938.55 y $ 1 461 388.35 respectivamente. Asimismo, también se valorizó en función a su potencial de desarrollo a través del método de preferencias reveladas y respectivamente en base a costos evitados, precios de mercado y función de producción, resultando los valores de $ 3 844 682.73, $ 454 938.55 y $ 7 254 869.32 respectivamente.
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Shrestha, Ajit, Ramesh Man Joshi i Upendra P. Devkota. "Coagulation disorder in moderate to severe traumatic brain injuries". Asian Journal of Medical Sciences 6, nr 3 (10.10.2014): 22–25. http://dx.doi.org/10.3126/ajms.v6i3.10730.

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Background: Significant proportions of patients presenting with moderate to severe traumatic brain injuries are diagnosed as having coagulation disorder and subsequent secondary brain injury. We evaluated the incidence of coagulopathy in patient with moderate to severe traumatic brain injury in this study.Methods: A prospective study of 100 patients with moderate to severe traumatic brain injury was carried out over a period of 2 years. Platelet count (PC), Bleeding time (BT), Clotting time (CT), Prothrombin time (PT), International Normalized ratio (INR), activated partial thromboplastin time (aPTT) and Fibrin degradation product (FDP) were measured at the time of admission and 12 hourly for 7 days. Daily D-dimer evaluation for DIC was performed in those who had abnormal value in any one of these parameters. Coagulopathy was classified as collectively 3 abnormal parameters.Results: Among the 100 patients, 43% had severe and 57% had moderate traumatic brain injury. Coagulopathy was detected in 63% of total patients; 76.7 % (33/43) among severe traumatic brain injury and 52.7 % (30/57) among moderate (p 0.013). Multivariate statistical analysis showed deranged FDP as a significant individual predictor of coagulopathy among others (p < 0.001, Odds ratio 166.25; 95% confidence interval 31.7 + 869.7).Conclusion: Coagulopathy is common in patients with moderate to severe traumatic brain injury. Evaluation of FDP can significantly predict coagulopathy in traumatic brain injury patients.DOI: http://dx.doi.org/10.3126/ajms.v6i3.10730 Asian Journal of Medical Sciences Vol.6(3) 2015 22-25
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Diaféria, Giovana, Silvana Bommarito, Pedro Braga Neto, Sung Woo Park, Marina Padovani, Fernanda Haddad, Leonardo Haddad i in. "Effect of speech therapy on quality of life in patients with spinocerebelar ataxia type 3". Arquivos de Neuro-Psiquiatria 80, nr 10 (październik 2022): 1017–25. http://dx.doi.org/10.1055/s-0042-1755203.

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Abstract Background Individuals with spinocerebellar ataxia type 3 (SCA3) present communication and swallowing disorders, and consequent deterioration in quality of life (QOL). Objective To evaluate the impact of a speech therapy rehabilitation program on the QOL of patients with SCA3. Methods All participants were randomly assigned to two groups, an intervention group receiving speech therapy (STG) and a control group (CG). The International Cooperative Ataxia Rating Scale scores were 32.4 ± 20.2, and the Scale for the Assessment and Rating of Ataxia scores were 11.8 ± 8.0. The intervention consisted of a 12-session speech therapy rehabilitation program with oral, pharyngeal, and laryngeal strengthening exercises—the so-called ATAXIA–Myofunctional Orofacial and Vocal Therapy (A-MOVT). They all were submitted to pre- and postintervention evaluations using the World Health Organization's Quality of Life (WHOQOL-BREF) assessment, as well as the Living with Dysarthria (LwD), Quality of Life in Swallowing Disorders (SWAL-QOL), and Food Assessment Tool (EAT-10). Results The study sample consisted of 48 patients with SCA3 (STG = 25; CG = 23), mean age was 47.1 ± 11.4 years; mean age at symptom onset was 36.9 ± 11.3 years; disease duration was 11.9 ± 13.3 years. After the 3-month intervention, there were significant changes in the QOL in the STG compared with the CG, when assessed by the LwD (179.12 ± 62.55 vs. 129.88 ± 51.42, p < 0.001), SWAL-QOL (869.43 ± 153.63 vs. 911.60 ± 130.90, p = 0.010), and EAT-10 (5.16 ± 7.55 vs. 2.08 ± 3.85, p = 0.018). Conclusions Patients with SCA3 should receive continuous speech therapy as part of the A-MOVT program, because therapy helps to improve difficulty swallowing and dysarthria.
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Książki na temat "869.3/3"

1

Assis, Machado de. O Alienista. Independently Published, 2022.

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Assis, Machado de. O Alienista: Literatura Clássica Brasileira. Independently Published, 2021.

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Assis, Machado de. O Alienista. Independently Published, 2020.

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Assis, Machado de. O Alienista. Independently Published, 2018.

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