Gotowa bibliografia na temat „571.430 485”

A glass system was prepared according to the formula 60mol%B2O3 – x mol %barite – (40-x) mol %Li2O, where x=0, 5, 7.5, 10, 15 and 20 mol%. The amorphous nature of the prepared glasses was confirmed through X-ray diffraction. The prepared glasses were also characterized by FTIR spectroscopy, UV-vis absorption spectroscopy and the differential thermal analysis (DTA). The density is found to increase and this is because of the higher molecular of the added barite. The molar volume also increases with increasing barite content that indicates the structural changes occurred in borate network that were also confirmed using FTIR. Increasing the concentration of barite shifts the UV cutoff edge toward higher wavelengths from about 300 nm at 0 mol% barite to about 400 nm at 15 mol% of barite. Glass transition temperature (Tg) is found to increase with the increasing barite content. When analyzed by photoluminescence, the samples exhibit luminescence emission centered at around 400, 415, 480, 430, 485, 520, 545, and 570 nm when excited at 300 nm wavelength. The emission peaks at 420 nm, and 440 nm were assigned to F center emission. Between 440 nm and 520 nm it is rather the effect of the presence of the impurities.

Chrześcijanie późnego antyku, mimo rosnącej roli chrześcijaństwa i uznania go za religię państwową, żyli w świecie, który nadal obfitował w różnorodne formy kultu po­gańskiego. Pogańskie wróżbiarstwo i liczne praktyki magiczne wciąż miały doskonałe warunki do rozwoju. Kulturowa i religijna działalność człowieka, mimo zakazów pań­stwowych i kościelnych, w naturalny sposób utrzymywała potrzebę podejmowania prób, za pomocą specjalnych środków i technik, poznania przyszłości lub wpłynięcia na los i przebieg wydarzeń. Takiej sytuacji sprzyjał fakt, że chrześcijanie nie żyli w izolacji, lecz współegzystowali z poganami na terenie Imperium Romanum. W niniejszej publi­kacji przedstawiono szczegółową analizę postanowień synodów obradujących od IV do VI w. w odniesieniu do wróżbiarstwa i praktyk magicznych. Analizie w tej kwestii pod­dano m.in. kanony ogłoszone w Elwirze (306), Arles (314), Laodycei we Frygii (koniec IV w.), Saliq w Seleucji-Ktezyfonie (410), Irlandii (456–465), Vannes w Bretanii (461–491), Galii (ok. 475–485), Agde (506), Orleanie (511), Eleuze (551) dwa razy ponow­nie w Seleucji-Ktezyfonie (544 i 554) oraz w Bradze (572) i Narbon (589). W celu pełniej­szego ukazania przywołanego w temacie zagadnienia omówiono również prawodawstwo cesarskie, ogłaszane w sprawach religijnych przez pierwszych chrześcijańskich cesarzy rzymskich, począwszy od Konstantyna aż do Arkadiusza. Analizie poddano przede wszystkim ustawy zawarte w 16 księdze Kodeksu Teodozjańskiego. W tym kontekście przywołano edykty cesarskie ogłoszone w latach 341, 381, 385, 392, 395 oraz 396.

Pamiętniki i relacje w zbiorach rękopiśmiennych BN (wydanie drugie poprawione i rozszerzone), oprac. Danuta Kamolowa przy współudziale Teresy Sieniateckiej, Warszawa: Biblioteka Narodowa, 2015, 539, [1] s., [26] k. tabl.: il., ISBN 978-83-7009-623-6 – Katarzyna Seroka [397-398]
 Anna Kocot, Artyści „czarnej sztuki”. Typografia druków Floriana Unglera i Macieja Wirzbięty, Kraków: Księgarnia Akademicka, 2015, ss. 416, ISBN/ISSN 978-83-76384-60-3 – Anna Kamler [398-403]
 Justyna Kiliańczyk-Zięba, Sygnety drukarskie w Rzeczypospolitej XVI wieku: źródła ikonografi czne i treści ideowe, Kraków: Wydawnictwo Towarzystwa Naukowego „SocietasVistulana”, 2015, ss. 342, [1]: il., ISBN 978-83-61033-89-9 – Katarzyna Seroka [403-405]
 Catalogue of books from the Library of Sigismund II Augustus, King of Poland, in the collection of the National Library of Russia in Saint Petersburg, ed. by Maria I. Tkachenko, Maria Brynda, National Library of Poland (Warsaw), National Library of Russia (Saint Petersburg),Warsaw: National Library of Poland, 2015, 198 [1] s., [21] s. tabl., ISBN 978-83-7009-621-2 – Karolina Figaszewska [405-406]
 Joanna Matyasik, Polonika XVI-XVII w. ze zbiorów Wojewódzkiej i Miejskiej Biblioteki Publicznej w Bydgoszczy. Katalog, Bydgoszcz: Wojewódzka i Miejska Biblioteka Publiczna im. Dr. Witolda Bełzy, 2015, ss. 345, ISBN 978-83-85979-21-0; 978-83-62545-86-5 – Agnieszka Chamera-Nowak [406-409]
 Polski wkład w przyrodoznawstwo i technikę: słownik polskich i związanych z Polską odkrywców, wynalazców oraz pionierów nauk matematycznoprzyrodniczych i techniki, t. 1-4, red. nauk. Bolesław Orłowski, Warszawa: Instytut Historii Nauki im. Ludwika i Aleksandra Birkenmajerów Polskiej Akademii Nauk, Instytut Pamięci Narodowej – Komisja Ścigania Zbrodni przeciwko Narodowi Polskiemu, 2015, t. 1 ss. 521, t. 2 ss. 437, t. 3 ss. 511, t. 4 ss. 543, ISBN 978-83-8606-229-4; 978-83-8606-228-7; 978-83-7629-829-0; 978-83-7629-828-3; 978-83-7545-569-4; 978-83-7545-570-0 – Sarah Skumanov [409-410]

The microstructure, hardness and corrosion resistance of AZ91D alloy were investigated under different solution treatments and artificial aging conditions.When ascast AZ91D alloy was heat treated at 415°C by solution treatmentfor 12 h and artificially aged at 200°C, the volume fraction of precipitates increased with the aging time up to 10 h.When ascast AZ91D alloy was treated at 430°C by solution treatment for 12 h and artificially aged at 200°C for 10h, the volume fraction of precipitates reached a peak value.The results of the corrosion test showed that a high corrosion resisting of the second phase precipitates was beneficial to improving the strength and hardness. Solution treatment at 445°C temperature for 12 h destroied the consecutiveness of β-Mg17Al12 phases.

ObjectivesTo evaluate the potential of soluble cluster of differentiation 146 (sCD146) in the detection and grading of congestion in patients with acute dyspnoea.DesignSubanalysis of the prospective observational Lithuanian Echocardiography Study of Dyspnoea in Acute Settings (LEDA) cohort.SettingTwo Lithuanian university centres.ParticipantsAdult patients with acute dyspnoea admitted to the emergency department.MethodsCongestion was assessed using clinical and sonographic parameters. All patients underwent sCD146 and N-terminal pro-B-type natriuretic peptide (NT-proBNP) testing.ResultsThe median value of sCD146 concentration in the study cohort (n=437) was 405 (IQR 315–509) ng/mL. sCD146 was higher in patients with peripheral oedema than in those without (median (IQR) 472 (373–535) vs 400 (304–501) ng/mL, p=0.009) and with pulmonary rales than in those without (439 (335–528) vs 394 (296–484) ng/mL, p=0.001). We found a parallel increase of estimated right atrial pressure (eRAP) and sCD146 concentration: sCD146 was 337 (300–425), 404 (290–489) and 477 (363–572) ng/mL in patients with normal, moderately elevated and high eRAP, respectively (p=0.001). In patients with low NT-proBNP, high sCD146 distinguished a subgroup with a higher prevalence of oedema as compared with patients with low levels of both biomarkers (76.0% vs 41.0%, p=0.010). Moreover, high sCD146 indicated a higher prevalence of elevated eRAP, irrespective of NT-proBNP concentration (p<0.05).ConclusionsCD146 concentration reflects the degree of intravascular and tissue congestion assessed by clinical and echocardiographic indices, with this association maintained in patients with low NT-proBNP. Our data support the notion that NT-proBNP might represent heart stretch while sCD146 rather represents peripheral venous congestion.

Abstract The paper reviews the main West-Carpathian Early Paleozoic metamorphosed originally sedimentary-magmatic complexes, dated by SHRIMP on zircons, as indicators of crustal extension and shortening events. Igneous precursors of a Layered Amphibolite Complex (LAC) – fractionated upper mantle gabbros to diorites, dated at 503 ± 4 and 492 ± 4 Ma from the North-Veporic, or 480 ± 5 and 450 ± 6 Ma from the Tatric basement are contemporaneous with subaluminous to metaluminous I-type (507 ± 4 Ma, the South-Veporic basement), peraluminous S-type (497 ± 4 Ma, the South-Veporic basement; 516 ± 7, 485 ± 6 and 462 ± 6 Ma, the North-Veporic basement; 497 ± 6, 472 ± 6 and 450 ± 6 Ma, the Tatric basement), alkaline A-type (511 ± 6 Ma, South-Veporic basement) granitic orthogneisses and calcalkaline rhyolitic (482 ± 6 Ma) and dacitic (476 ± 7 Ma) metavolcanics (Gemeric basement), indicating a magmatic immature back arc setting. The ages point to Middle/Late Cambrian, Early and Late Ordovician magmatic phases, coeval with the extension in the northern Gondwana margin. Separation of an inferred Avalonian and/or Galatian terranes distal continental ribbon corresponds with the opening of a Medio-European Basin. A 430-390 Ma dated MP/HP metamorphic event, recorded in the LAC and associated orthogneisses, occurred in the area of thinned immature back arc basin crust due to closure of the Medio-European Basin. Thus a distal Gondwana continental ribbon north of this basin could be an eastward lateral pendant of Armorica, derived from Galatian terrane. Metaophiolites of the Pernek Group (a metagabbrodolerite dated at 371 ± 4 Ma) in the Tatric basement, analogous to island-arc tholeiites and back-arc basin basalts, indicate a back-arc basin setting north of a 430-390 Ma old northward dipping subduction/collision zone, dividing the northward drifting western Galatian terrane microplate from the Gondwana margin. Some metabasites of the Gemeric basement might indicate Late Devonian to Mississippian opening of a peri-Gondwanan Paleotethyan oceanic basin: a 383 ± 3 Ma old remelted metagabbro (482 ± 9 Ma) from the Klátov gneiss-amphibolite complex, ca. 385 Ma old porphyritic metabasite of the Zlatník ophiolite complex, as well as a 350 ± 5 Ma old HP metabasite as tectonic fragment within the Rakovec Group. The closure of Devonian-Mississippian basins, accompanied by medium-pressure (the Pernek Group) to high-pressure (blueschist to eclogitic tectonic fragments in greenschist facies rocks of the Rakovec Group) metamorphism, occurred in late Carboniferous to early Permian, when Paleotethyan realm complexes accreted to a Galatian terrane microplate, the latter represented by the older and the higher-grade Tatric and Veporic basement complexes.

435 Background: HCC is the third commonest malignancy worldwide, with the highest incidence rates in patients over 75 years of age. Although sorafenib is used for patients with advanced HCC, there are concerns about the outcomes and tolerability in this age group. Methods: We conducted a retrospective study of 190 patients treated with sorafenib (177 with sorafenib alone, 17 patients with a combination of sorafenib and erlotinib/placebo within the SEARCH trial). Patient demographics and outcomes were recorded. Results: 190 patients were identified with a median age of 66 (26-87). 151 patients were <75 years old (yrs) and 39 patients were >75. 157 patients were male and 33 female. Underlying liver disease in the over 75 group were: non-alcoholic fatty liver disease (N=14, 35.9%), unknown aetiology (N=14, 35.9%), alcoholic liver disease (N=7, 17.9%), hepatitis C (N=2, 5.1%), hepatitis B (N=1, 2.56%,) and autoimmune hepatitis (N=1, 2.56%). 33 patients were Child-Pugh A status when starting sorafenib (A5=25, A6=8) and 6 patients were Child-Pugh B (B7=5, B8=1). There was no statistically significant difference in OS between patients over the age of 75 and younger (7.1m for >75 yrs and 10.4 <75 yrs p=0.360), or in PFS (4.2m vs. 6.8m [p=0.539]). There was also no increase in G3/4 toxicities between both groups of patients with comparable incidences of G3/4 diarrhoea (4.7% <75 vs. 2.6% ≤75 p=0.481), skin toxicity (6.6% vs. 5.1% p=0.537), fatigue (7.3% vs. 7.7% p =0.58) and deteriorating liver function (2.6% vs. 7.3% p = 0.25). There was no difference between the incidence of dose reductions or interruptions (34% vs. 35.9% p=0.5). Conclusions: Our study suggests that patients aged 75 or older appear to tolerate treatment with sorafenib well with comparable toxicities to those less than 75. We also found no significant differences in survival. With an aging population and increasing incidences of HCC, further prospective evidence is needed to identify safety and survival outcomes in this important group of patients.

The effect of cationic (hexadecylpyridinium bromide, hexadecyltrimethylammonium bromide, Septonex), anionic (sodium dodecyl sulfate) and nonionic (Brij 35, Triton X-100) surfactants on the deprotonation of the phenolic oxygen in bromophenol red, bromophenol blue and bromocresol green is studied. The conditional dissociation constants Kai* depend on the surfactant concentration and, in the alkylpyridinium surfactant series, on the alkyl chain length at a constant concentration of inert electrolyte, and on the concentration of the inert electrolyte (Cl-, Br-, NO3-, SO42-, H2PO4-, CH3COO-, HCOO-, ClO4-) or of the sulfophthalein dye at a constant concentration of a cationic surfactant. In acid and alkaline solutions, cationic surfactants (tensides, T) and the dyes (H2L) form ionic associates with the stoichiometric composition {T+, LH-} and {T2+, L2-}, respectively, exhibiting absorption maxima at 400-430 nm (ε = 1.3-2.0 m2 mmol-1) and at 570-630 nm (ε = 3.5-4.5 m2 mmol-1), respectively, formation of these associates was confirmed for chloroform extracts by the continuous variations and molar ratios methods.

3112 Background: Human epidermal growth receptor 2 (HER2) is a well-known oncogenic drive gene with multiple targeted therapeutic options. In this study, we aim to assess the landscape of HER2 alterations in solid tumors and evaluate the feasibility of circulating tumor DNA (ctDNA) tested by next-generation sequence (NGS) as a tool to detect HER2 alterations. Methods: Alterations of HER2 by NGS (Illumina NextSeq 500) were queried in 3D Medicines database. The mean depth of tissue and circulating tumor DNA (ctDNA) test was 500X and 5000X, respectively. 11,013 patients tested using tumor tissue and 6,970 patients tested using ctDNA were included in this analysis. Results: Of 11,013 patients tested using tumor tissue, any HER2 and known or likely deleterious HER2 mutations were identified in 739 (6.7%) and 531 (4.8%) patients, respectively. Of 531 patients who carried known or likely deleterious HER2 mutations, 263 (49.5%) had HER2 amplification and 259 (48.8%) had single nucleotide variations (SNVs). Across all tumor types, breast cancer was found to have the highest frequency of HER2 amplification (14.9%, 48/323), followed by gastric cancer (6.6%, 31/470) and biliary tract cancer (5.8%, 33/571). Moreover, 11% (8/73) of duodenal cancer, 4.5% (7/154) of urothelial cancer, 3.8% (18/470) of gastric cancer, 3.1% (142/4555) of lung cancer, 2.9% (17/571) of biliary tract cancer, 2.8% (44/1562) of colorectal cancer and 2.7% (9/323) of breast cancer carried known or likely deleterious HER2 SNVs. Of 6970 patients tested using ctDNA, any HER2 and known or likely deleterious HER2 mutations were identified in 592 (8.5%) and 277 (4.0%) patients, respectively. In the ctDNA cohort, 15.7% (36/230) of breast cancer and 3.1% (5/161) of biliary tract cancer carried HER2 amplification. However, 11.6% (20/173) of gastric cancer had HER2 amplification tested by ctDNA which was higher than that tested using tissue. Furthermore, 5.6% (13/230) of breast cancer, 4.5% (2/44) of urothelial cancer, 3.4% (6/173), 2.5% of biliary tract cancer and 2.0% (94/4586) lung cancer harbored known or likely deleterious HER2 SNVs in ctDNA cohort. Conclusions: HER2 alterations existed across tumor types and the landscape of genomic alterations in HER2 gene varied according to different type of tumor. In addition, ctDNA can be used as a potential tool to detect HER2 alterations.