Artykuły w czasopismach: „306/.9”

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Huang, Wentao, Zhifang Liu, Yifan Li, Heng Pan, Yuan Li, Xia Qin, Da Fei i Runsheng Li. "Abstract 1881: Pre-clinical evaluation of a novel antibody drug conjugate (ADC) LM-306 targeting IL-13Rα2 in immuno-oncology". Cancer Research 83, nr 7_Supplement (4.04.2023): 1881. http://dx.doi.org/10.1158/1538-7445.am2023-1881.

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Abstract Interleukin-13 receptor alpha 2 (IL-13Rα2) is overexpressed in various types of cancers including glioma and melanoma and is known to be associated with increased tumor invasiveness and metastases. Here, we present the preclinical efficacy and toxicity results for a novel, anti-IL-13Rα2 ADC-LM-306. In vitro binding activity and internalization of LM-306 and LM-106 (unconjugated antibody of LM-306) were assessed in human IL-13Rα2 overexpressing and endogenous cell lines using flow cytometry. The antibody-dependent cell-mediated cytotoxicity (ADCC) and direct cytotoxicity were assessed using viability assays. Cross-species reactivity of drug was assessed in cells expressing cynomolgus, rat and mouse IL-13Rα2. In vivo A375 CDX model was used to assess the effect of LM-306 anti-tumor activity. The toxicity of LM-306 was evaluated in repeated-dose intravenous dose range-finding (DRF) toxicity and single intravenous maximum tolerated dose (MTD) study in cynomolgus monkeys. Both LM-106 and LM-306 showed concentration dependent binding affinity to IL-13Rα2 in various cell lines (Table 1). In addition, LM-106 also showed a dose dependent internalization and ADCC and LM-306 showed significant cytotoxicity in all cell lines (Table 1). Furthermore, LM-306 showed comparable binding affinity to human IL-13Rα2 to its unconjugated counterpart LM-106 (KD:7.43E-10 vs 1.77E-9). LM-306 was also found to be cross-reactive toward cynomolgus IL-13Rα2. In vivo, LM-306 showed tumor growth inhibition at a dose of 1, 3, 10 mg/kg given intravenously once weekly, indicating its strong anti-tumor activity. The highest non-severely toxic dose of LM-306 was determined to be 9 mg/kg in the DRF study and MTD was determined to be 18mg/kg in MTD study for male monkey. In summary, LM-306 showed high binding affinity to human IL13Rα2 expressing cells with potent cytotoxicity in vitro and significant in vivo inhibition of tumor growth, suggesting its therapeutic benefit in immuno-oncology. Summary of parameters of LM-106 and LM-306 binding affinity, internalization, ADCC and cytotoxicity Assay Antibody EC50 (nM) HEK293/H_IL-13Rα2 U251 A375 SKMEL5 Binding affinity LM-106 0.99 0.21 0.57 0.1 LM-306 1.47 0.33 0.8 0.12 Internalization LM-106 2.22 - 0.43 - ADCC LM-106 0.16 - 0.03 - LM-306 0.31 - 0.03 - Cytotoxicity (IC50) LM-306 0.03 0.05 0.01 0.005 Citation Format: Wentao Huang, Zhifang Liu, Yifan Li, Heng Pan, Yuan Li, Xia Qin, Da Fei, Runsheng Li. Pre-clinical evaluation of a novel antibody drug conjugate (ADC) LM-306 targeting IL-13Rα2 in immuno-oncology [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 1881.

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Cabrera Becerra, Gabriel. "Livia Raponi (Org). (2016) A única vida possível. Itinerários de Ermanno Stradelli na Amazônia". Mundo Amazónico 11, nr 1 (1.01.2020): 126–29. http://dx.doi.org/10.15446/ma.v11n1.87393.

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Niayesh, H., i M. Aagard. "COMPLEMENTARY FEEDING PRACTICES IN AFGHANISTAN". International Journal of Advanced Research 8, nr 10 (31.10.2020): 259–71. http://dx.doi.org/10.21474/ijar01/11852.

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Background: Children in Afghanistan are at greater risk of malnutrition. Over 50% of children were suffering from malnutrition in Afghanistan in 2012, which has a long-lasting physical, mental, social, and impact on children. Study purpose: The purpose of this research study was to explore the association between parents knowledge, attitudes, and practices about complementary feeding and stunting in children in Afghanistan. The predictor variables were mothers knowledge, attitudes, and practices about complementary feeding and the outcome variable was stunting status of children aged 6 to 24 months. Research methods:A quantitative cross-sectional survey was conducted with randomly selected participants who were living in Kabul, Afghanistan. Logistic regressionmodels were used to analysethe data. Research setting: This research was conducted in 6 hospitals in Kabul, Afghanistan. Study participants: The study participants included 306 mothers who had children aged between 6-24 months. Results: Mothers knowledge, attitudes, and practices were significant predictors of stunting in children, χ2 (9, N = 306) = 45.33, p < .001 χ2 (9, N = 306) = 26.71, p < .01 and χ2 (9, N = 306) = 56.97, p <.001.Mothers who did not practice responsive feeding were 7.1 times more likely to have stunted children than mothers who practiced responsive feeding. Social and policy implications: The social and policy implications of this research study include reviewing nutrition policies, investing in nutrition programs, and increasing public education and awareness in promoting appropriate complementary infant feeding practices in Afghanistan.

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Glower, Donald D., Teng Lee i Bhargavi Desai. "Aortic Valve Replacement through Right Minithoracotomy in 306 Consecutive Patients". Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery 5, nr 5 (wrzesień 2010): 326–30. http://dx.doi.org/10.1097/imi.0b013e3181f64e54.

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Objective To define the role and early results of aortic valve surgery through a right minithoracotomy. Methods A retrospective analysis was performed on 306 consecutive patients undergoing aortic valve replacement through an 8-cm right minithoracotomy in the second intercostal space. The initial experience was included. The right second and third ribs were detached from the sternum in most cases and repaired at the end of each case. Most operations were performed using anterograde and retrograde cardioplegic arrest with percutaneous femoral venous cannulation and direct aortic cannulation through the incision. Standard instruments were used with direct digital knot tying. Results Mean age was 65 ± 14 (range, 20–90) years. Aortic valve disease cause was calcific disease in 160 of 306 (52%) patients, bicuspid disease in 95 of 306 (31%) patients, and endocarditis in 9 of 306 (3%) patients. Previous cardiac surgery was present in 13 of 306 (4%) patients. Biologic prostheses were used in 240 of 306 (78%) patients. Median valve size was 23 mm. Mean clamp times and pump times were 103 ± 26 and 158 ± 35 minutes, respectively. Median postoperative length of stay was 5 days. Thirty-day mortality was found in 4 of 306 (1%) cases. There were no deep wound infections or mediastinitis. Stroke occurred in 5 of 306 (1.6%) patients, and new pacemaker required in 11 of 306 (4%) patients. Reoperation for bleeding occurred in 2 of 306 (1%) patients. Conversion to median sternotomy occurred in 15 of 306 (5%) patients caused by chest wall anatomy (n = 7), bleeding (n = 3), coronary disease (n = 2), or aortic disease (n = 3). Patients were allowed to return to driving or preoperative activity in 2 weeks. With a mean follow-up of 2.8 ± 2.2 years, one patient required reoperation for aortic root disease. Conclusions Right minithoracotomy is a safe but limited alternative to sternotomy in isolated aortic valve replacement. This approach may be particularly valuable in some higher risk, elderly patients and opens options for a hybrid approach combined with percutaneous coronary angioplasty.

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Kitzing, Michael, i Christhard Schrenk. "Rezension von: Christhard Schrenk (Hg.): Die 1960er Jahre in Heilbronn. Erinnerungen, Erkenntnisse, Aktualität". Zeitschrift für Württembergische Landesgeschichte 78 (21.01.2022): 603–5. http://dx.doi.org/10.53458/zwlg.v78i.1574.

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Christhard Schrenk (Hg.), Die 1960er Jahre in Heilbronn. Erinnerungen, Erkenntnisse, Aktualität (Kleine Schriftenreihe des Archivs der Stadt Heilbronn 66), Stadt Heilbronn 2018. 306 S., Ill. ISBN 978-3-940646-27-9. € 17,50

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A, AMIRTHA DEVARATHINAM. "HETEROSIS AND COMBINING ABILITY IN INTER-SPECIFIC HYBRIDS BETWEEN CMS OF Bajra AND NAPIER GRASS". Madras Agricultural Journal 82, November (1995): 578–81. http://dx.doi.org/10.29321/maj.10.a01268.

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General and specific combining ability variances and effects for seven fodder characters were studied in, bajra-napier interspecific hybrids obtained in line x tester programme involving 9 CMS lines of bajra as female and 6 genotypes of napier grass, as male. The mean squares due to general and specific combining ability were significant indicating the importance of both additive and dominance components. The magnitude of sca variances was greater than that of gca for all characters suggesting the predominance of non-additive gene action. The parents, 405 A, 306 A, and 732 A among the CMS lines of bajra and FD 466 and FD 435 among napier grass were identified as best general combiners. The crosses 306 A x FD 466, 306 Ax FD 435, 437 were the best specific combinations for forage yield. High heterosis observed for different forage yield characters was mostly due to the desirable sca effects.

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Łopaczyk, Justyna. "Prasa dla dzieci i młodzieży 1824–1918". Biblioteka, nr 23(32) (15.12.2019): 379–91. http://dx.doi.org/10.14746/b.2019.23.20.

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Recenzja. Prasa dla dzieci i młodzieży 1824–1918, Kraków: Wydawnictwo Naukowe Uniwersytetu Pedagogicznego 2018, s. 362 (tom 1, ISBN 978-83-8084-181-9), s. 343 (tom 2, ISBN 978-83-8084-183-3), s. 306 (tom 3, ISBN 978-83-8084-185-7)

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Yang, Haichuan, Xiankun Ren, Yating Zhao, Tengjiao Xu, Jing Xiao i Hao Chen. "Enhancing Alkaline Protease Stability through Enzyme-Catalyzed Crosslinking and Its Application in Detergents". Processes 12, nr 3 (21.03.2024): 624. http://dx.doi.org/10.3390/pr12030624.

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Enzymatic additives, particularly alkaline proteases, play a crucial role in enhancing detergent effectiveness against protein-based stains. Despite advancements in enzyme stabilization techniques, there is a need for innovative strategies to further improve protease stability in laundry detergents. However, research exploring the utilization of substrate imprinting technology to achieve this objective remains limited. Therefore, this study aims to enhance the stability of alkaline proteases in laundry detergents by employing casein as an imprinting substrate and utilizing transglutaminase-mediated (TGase) crosslinking to modify proteases 102 and 306. The optimal temperature, pH, and thermal stability of the modified alkaline proteases 102 and 306 showed no significant changes. However, these two modified alkaline proteases exhibited varying degrees of improvement in stability among the 14 detergent additives tested. Under 40 °C incubation for 24 h, the relative enzyme activity of modified alkaline protease 102 increased approximately 1.4–15-fold in AEO-9, BS-12, CMI, APG, FMEE, and SOE, while the relative enzyme activity of modified alkaline protease 306 increased approximately 1.2–3.7-fold across different additives (FMEE, AEO-9, BS-12, SOE, FAA, and AEC-9Na). These modified proteases demonstrated improved stability and wider applicability across commercial detergent formulations available. Integrated into standard laundry detergent at a 1:7 ratio before and after modification, they effectively removed protein stains from the cotton fabric after 24 h of 40 °C incubation. These findings provide insights into more effective stain-removal techniques.

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Carlson, David R. "Un autre témoin anglo-saxon de P. Optatianus Porphyrius". Scriptorium 71, nr 1 (2017): 115–20. http://dx.doi.org/10.3406/scrip.2017.4430.

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In addition to the manuscript reported by Hubert Silvestre in 1963, another pre-conquest English manuscript (Durham, Dean and Chapter Library, B. IV. 9) transmits some of the enigmatic verse of Publilius Optatianus Porphyrius (fl. c. 306-333), further attesting to the circulation of his work in Anglo-Saxon England. The manuscript’s textual witness has not been previously reported.

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Ye, Qin, Jennifer S. Woo, Qunzi Zhao, Ping Wang, Pintong Huang, Lirong Chen, Xin Li i in. "Fine-Needle Aspiration Versus Frozen Section in the Evaluation of Malignant Thyroid Nodules in Patients With the Diagnosis of Suspicious for Malignancy or Malignancy by Fine-Needle Aspiration". Archives of Pathology & Laboratory Medicine 141, nr 5 (1.05.2017): 684–89. http://dx.doi.org/10.5858/arpa.2016-0305-oa.

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Context.— The Bethesda System for Reporting Thyroid Cytopathology recommends against the use of intraoperative frozen section (FS) during lobectomy of a thyroid nodule with a fine-needle aspiration (FNA) diagnosis of malignant. Bethesda recommendations for FS in the FNA category of suspicious for malignancy (SFM) is less well-defined. In some institutions in China, FS examination is performed during lobectomy even for FNA-proven malignant cases. Objective.— —To compare the efficacy of FNA versus FS in the evaluation of malignant thyroid lesions. Design.— A 3-year retrospective analysis from a single institution was performed on cases with an FNA diagnosis of SFM or malignant with subsequent FS examination during thyroidectomy. The results of FNA and FS findings were compared to the final thyroidectomy pathology. Results.— —A total of 5832 thyroidectomy procedures were performed: 1265 cases had FNA and FS results available. Fine-needle aspiration gave a diagnosis of SFM to 306 cases and a diagnosis of malignant to 821 cases. Of the SFM cases, 10.5% (32 of 306) had benign/indeterminate, 4.6% (14 of 306) suspicious, and 84.9% (260 of 306) malignant FS results. Final pathology showed 56.3% (18 of 32), 64.3% (9 of 14), and 100% (260 of 260) malignancy rates, respectively. For the malignant FNA group, 10.0% (82 of 821) had benign/indeterminate, 4.4% (36 of 821) suspicious, and 85.6% (703 of 821) malignant FS results. The final pathology showed 96.4% (79 of 82), 97.2% (35 of 36), and 99.9% (702 of 703) malignancy rates, respectively. Conclusions.— Frozen section should not be performed for the malignant FNA category because FS evaluation may result in 10% falsely negative findings. Performing FS for SFM may be better justified; however, more than half of FS cases read as benign in this category had malignant final pathology. Therefore, caution should be taken for FS results even in the SFM group.

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BULLOCK, G. "Stains and cytochemical methodsby M.A. Hayat, Plenum Press, 1993. $106.00 (455 pages) ISBN 0 306 44294 9". Trends in Cell Biology 4, nr 3 (marzec 1994): 106–7. http://dx.doi.org/10.1016/0962-8924(94)90186-4.

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GIORDANO, P., M. ROUIF, B. LAURENT i J. MATEU. "Endoscopic transaxillary breast augmentation: Clinical evaluation of a series of 306 patients over a 9-year period". Aesthetic Surgery Journal 27, nr 1 (styczeń 2007): 47–54. http://dx.doi.org/10.1016/j.asj.2006.12.012.

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da Silva, Romario J., Nara C. de Souza i Josmary R. Silva. "Photoproducts Formation from Salicylic Acid and Poly(allylamine hydrochloride) in Aqueous Solution Induced by UV-B Radiation". Advances in Condensed Matter Physics 2015 (2015): 1–6. http://dx.doi.org/10.1155/2015/471809.

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We report on the investigation of the influence of UV-B radiation (306 nm) on the salicylic acid mixed with poly(allylamine hydrochloride), PAH, in aqueous solution. UV-Vis spectra versus irradiation time reveal kinetics of photoproducts formation. At pH 9 and 10 are found a growth regime and another of decay of photoproducts formation. In addition, the growth does not depend on temperature, whereas the decay showed a significant dependence on this parameter suggesting a thermally activated process. These processes were well fitted with first-order exponential functions.

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Majumder, Rinku, JinMing Wang i Barry R. Lentz. "C6PS Regulates the Inactivation of Factor Va by Activated Protein C." Blood 106, nr 11 (16.11.2005): 1023. http://dx.doi.org/10.1182/blood.v106.11.1023.1023.

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Abstract Protein C is a vitamin K-dependent, anti-thrombotic protein that is proteolytically cleaved by thrombin to produce the active serine protease, activated protein C (APC). APC inactivates co-factors Va and VIIIa, leading to down-regulation of thrombin generation. Factor Va requires phosphatidylserine (PS) for full cofactor activity. APC inactivates bovine factor Va by catalyzing cleavage in its heavy-chain at Arg505, Arg 662 and Arg306. The cleavage at Arg 306 is stimulated by PS-containing membranes. In this paper, we use water-soluble 2-dicaproyl-sn-glycero-3-phospho-L-serine (C6PS) to ask whether a membrane or molecular PS regulates inactivation of factor Va by APC. Synthetic substrate titration suggested that APC has two Ca2+-requiring binding sites for C6PS: one site increased the APC amidolytic activity (Kdeff ~ 1.3 μM) while the other site decreased it (Kdeff ~ 2 μM) in the presence of 2 mM Ca2+. The effect of C6PS on APC amidolytic activity was PS-specific, with C6PE having no effect. However, titration of both intrinsic fluorescence and DEGR ([5-(dimethylamino)-l-naphthalenesulfonyl] glutamylycylarginyl chloromethyl )-labeled APC fluorescence showed only one Ca2+-requiring C6PS binding site (Kdeff ~ 0.8 μM). The fluorescence anisotropy of DEGR-APC in the presence of 200 μM C6PS revealed C6PS-dependent 1:1 binding to both factor Va isoforms (Va1or Va2) with Kdeff of 1.13x10-9 M (Va1) and 0.3x10-9 M (Va2). The inactivation of factors Va1/Va2 by APC was also promoted by C6PS. In the presence of 200 μM C6PS to saturate sites on both APC and factor Va, both factors Va1/Va2 were fully inactivated by APC (indicating cleavage at Arg 306). However, in the absence of C6PS or presence of only 4 μM C6PS (sufficient to saturate sites only on APC), only partial inactivation (48–52%) of factor Va1/Va2 was observed. These results suggest that PS binding to APC may have some effect on cleavage at Arg505 or Arg 662 but that PS binding to factor Va was needed to promote cleavage at Arg 306. Supported by USPHS grant HL072827 to BRL.

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Middleburgh, Charles, Marc Saperstein, Ursula Rudnick i Lia D. Shimada. "Book Reviews". European Judaism 52, nr 1 (1.03.2019): 150–60. http://dx.doi.org/10.3167/ej.2019.520116.

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Bar Mitzvah: A History, by Rabbi Michael Hilton, University of Nebraska Press/Jewish Publication Society, 2014, ISBN: 978-0-8276-0947-1, 360pp., £22.99The Beginnings of Ladino Literature: Moses Almosnino and His Readers, by Olga Borovaya, Bloomington, Indiana University Press, 2017, ISBN: 978-0- 253-02552-4 (hardback), 317 pp., $60.00Deep Calls to Deep: Transforming Conversations between Jews and Christians, edited by Tony Bayfield, London, SCM, 2017, ISBN: 978-0-334-05512-9 (paperback), 368 pp., £40.00Confessions of a Rabbi, by Jonathan Romain, London, Biteback Publishing, 2017, ISBN: 978-1-78590-189-8 (paperback), 306 pp., £12.99

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Faradilla Suciani, Hamidah Faradilla Suciani, Suci Dwinitia i Upit Yulianti Dn. "Pengaruh Model Pembelajaran Problem Based Learning Terhadap Elemen Menulis Negosiasi Fase E SMA Negeri 9 Mandau". ALINEA : Jurnal Bahasa, Sastra dan Pengajarannya 3, nr 2 (31.08.2023): 518–28. http://dx.doi.org/10.58218/alinea.v3i2.678.

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This research aims to describe the effect of the Problem Based Learning Method on Learning to Write Negotiation Texts for Class X Students of SMA Negeri 9 Mandau. This type of research is quantitative research with experimental methods. The population of this study were 306 students of class X SMA Negeri 9 Mandau who were enrolled in the 2023/2024 academic year. The sample of this research is class X.2 students. The data in this study are the performance scores of the ability to write negotiating texts of class X students of SMA Negeri 9 Mandau before and after using the Problem Based Learning Method. The results of this study are based on data analysis, namely that there is a significant effect of using the Problem Based Learning method on the ability to write negotiating texts for class X students of SMA Negeri 9 Mandau because tcount>ttable on degrees of freedom (dk)=n1-1 and (α)=0.05 significant level of 95%.

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Albarzanji, Pishwar Kh, i Saad A. Alhamdani. "The Consequences of Petrophysical Effects on Reservoir Properties of Hartha Formation at Balad Oil Field, Central Iraq". Journal of Petroleum Research and Studies 14, nr 1 (20.03.2024): 1–17. http://dx.doi.org/10.52716/jprs.v14i1.776.

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Hartha Formation (Upper Companian-Mastrechtian Sequence) consists mainly of detrital organic limestone and dolomitic limestone and may contains streaks of marl and through the petrographic study of the rocks of the formation, it was found that it consists of skeletal granules consisting of benthic foraminifera represented by fossils (orbitoid, rotalide and miliolide) and a few planktonic foraminifera belonging to the family of Globigerinacea and red, green algae, echinoderms, mollusks and the Formation also contained a few Calcispheres and these granules appeared affected by several modifying processes, the most important of which are Dolomitization, recrystallization, dissolution, Micritization and chemical compression and it was found through the analysis of the Microfacie that the Formation consists of four main, microfascies the upper limit of the Formation is conformable with the Formation of the Shiranish, while the lower limit represents unconformable with the Formation of Mashura. The present study focused on the effect of Diagenesis processes on the Hartha Formation in four subsurface sections within the Balad field in Salah al-Din Governorate in central Iraq, representing the first section (Ba-1) with a thickness of (443) m, the second section (Ba-5) with a thickness of (306) m, the third section (Ba-7) with a thickness of (306) m. (Ba-9) and thickness (307) m. Where (355) slides consisting of rock cutting and cores were studied, (144) slides for the well (Ba-1), (58) slides for the well (Ba-5), (54) slides for the well (Ba-7) and in the well (Ba-9). It was by (99) slides, as well as the logs of the above wells, through which the Formation was divided into three porous units.

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Shilkret, Robert. "Brenda Maddox.Freud's Wizard: Ernest Jones and the Transformation of Psychoanalysis. Cambridge, MA: Da Capo Press, 2006. 354 pp. $26.00 (cloth). ISBN 0-306-81555-3. $17.50 (paper). ISBN 0-306-81555-9". Journal of the History of the Behavioral Sciences 44, nr 4 (czerwiec 2008): 366–67. http://dx.doi.org/10.1002/jhbs.20332.

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Marín-Porgueres, Francisco J. "Emilio LLEDÓ, Memoria de la ética, Taurus, Madrid 1994, 320 pp., 21 x 13, ISBN 84-306-0094-9." Scripta Theologica 31, nr 1 (23.01.2018): 283. http://dx.doi.org/10.15581/006.31.15708.

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Cohen, Maayan, Dana Ashkenazi, Haim Gitler i Oren Tal. "Archaeometallurgical Analysis of the Provincial Silver Coinage of Judah: More on the Chaîne Opératoire of the Minting Process". Materials 16, nr 6 (9.03.2023): 2200. http://dx.doi.org/10.3390/ma16062200.

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Silver coins were the first coins to be manufactured by mass production in the southern Levant. An assemblage of tiny provincial silver coins of the local (Judahite standard) and (Attic) obol-based denominations from the Persian and Hellenistic period Yehud and dated to the second half of the fourth century BCE were analyzed to determine their material composition. Of the 50 silver coins, 32 are defined as Type 5 (Athena/Owl) of the Persian period Yehud series (ca. 350–333 BCE); 9 are Type 16 (Persian king wearing a jagged crown/Falcon in flight) (ca. 350–333); 3 are Type 24 series (Portrait/Falcon) of the Macedonian period (ca. 333–306 BCE); and 6 are Type 31 (Portrait/Falcon) (ca. 306–302/1 BCE). The coins underwent visual testing, multi-focal light microscope observation, XRF analysis, and SEM-EDS analysis. The metallurgical findings revealed that all the coins from the Type 5, 16, 24, and 31 series are made of high-purity silver with a small percentage of copper. Based on these results, it is suggested that each series was manufactured using a controlled composition of silver–copper alloy. The findings present novel information about the material culture of the southern Levant during the Late Persian period and Macedonian period, as expressed through the production and use of these silver coins.

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Đinh, Thúy Linh, Hải Yến Hoàng, Thế Vương Phạm, Thị Minh Thu Trần, Đức Nghĩa Nguyễn, Tài Đức Nguyễn i Duy Ánh Nguyễn. "Ứng dụng kỹ thuật array CGH trong chẩn đoán trước sinh một số bất thường nhiễm sắc thể tại Bệnh viện Phụ sản Hà Nội". Tạp chí Phụ sản 20, nr 3 (7.10.2022): 32–35. http://dx.doi.org/10.46755/vjog.2022.3.1429.

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Trong chẩn đoán trước sinh các bất thường nhiễm sắc thể (NST), kỹ thuật nuôi cấy tế bào ối hiện vẫn là tiêu chuẩn vàng. Tuy nhiên, chỉ phát hiện được các bất thường với kích thước > 5 Mb (trên 5 triệu cặp Base). Kỹ thuật array CGH (Microarray-based comparative genomic hybridization) có khả năng đánh giá trên toàn bộ 24 NST giúp phát hiện các bất thường mất cân bằng của NST bao gồm các trường hợp lệch bội, mất hoặc nhân đoạn của NST. Hơn nữa, kỹ thuật array CGH cho phép phát hiện các bất thường của NST ngay cả khi không có định hướng trong chẩn đoán. Mục tiêu: Xác định tỷ lệ bất thường một số nhiễm sắc thể qua kỹ thuật array CGH tại Bệnh viện Phụ sản Hà Nội. Đối tượng, phương pháp nghiên cứu: 306 thai phụ có tuổi thai 17 - 28 tuần có chỉ định chọc hút nước ối tại Bệnh viện Phụ sản Hà Nội từ 10/2020 - 09/2021, mẫu nước ối được thực hiện đồng thời 2 kỹ thuật: array CGH và nuôi cấy tế bào ối. Kết quả: Kỹ thuật karyotype phát hiện được 35/306 (11,4%) bất thường nhiễm sắc thể, trong khi đó array CGH phát hiện được 51/306 (16,7%). Array CGH phát hiện 25 trường hợp bất thường lệch bội, tương đương karyotype. Với các bất thường mất đoạn/nhân đoạn lớn, kỹ thuật array phát hiện được 9 trường hợp, trong khi đó karyotype phát hiện được 8 trường hợp; với các mất đoạn/nhân đoạn nhỏ, array CGH phát hiện được 16 trường hợp trong khi karyotype chỉ phát hiện được 1 trường hợp. Kết luận: Array CGH là xét nghiệm có độ chính xác cao, phát hiện được các trường hợp bất thường cấu trúc nhiễm sắc thể ở mức độ mất đoạn/nhân đoạn nhỏ mà kỹ thuật karyotype không phát hiện được.

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Rasmussen, Birgit Brander. "“Attended with Great Inconveniences”: Slave Literacy and the 1740 South Carolina Negro Act". PMLA/Publications of the Modern Language Association of America 125, nr 1 (styczeń 2010): 201–3. http://dx.doi.org/10.1632/pmla.2010.125.1.201.

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It was early morning on Sunday, 9 September 1739. While most South Carolina settlers were preparing for church, nearly Two dozen slaves gathered near the Stono River less than twenty miles from Charlestown. After attacking a local store to secure firearms, the group moved south toward Saint Augustine, Florida, swelling in number and spreading terror along the way. The rebels killed more than twenty settlers and set numerous buildings on fire before being defeated by a colonial militia at the Edisto River the following day (Wood 306-26). This unprecedented insurrection rocked the colony to its core and brought about legislation with important implications for literacy in the colonies that became the United States.

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Haniyah, Dinda, i Joko Soebagyo. "Analisis Bibliometrik Terhadap Kemampuan Komunikasi Matematis Dalam Pembelajaran Matematika Berdasarkan Perbedaan Gender berbasis VOSViewer". Buana Matematika : Jurnal Ilmiah Matematika dan Pendidikan Matematika 11, nr 2 (26.12.2021): 121–36. http://dx.doi.org/10.36456/buanamatematika.v11i2.3966.

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Dalam kemampuan komunikasi matematis sangat penting untuk dimiliki oleh siswa. Tujuan penelitian ini adalah untuk mengkaji penelitian mengenai kemampuan komunikasi matematis siswa dalam pembelajaran matematika berdasarkan perbedaan gender selama enam tahun belakangkan ini. Teknik pengumpulan data dengan cara penelusuran menggunakan Google Scholar dengan kata kunci mathematical, communication, gender, dalam kurun waktu 2015-2021. Analisis data menggunakan software VOSviewer dengan data yang didapatkan dari software Publish or Perish. Kesimpulan dari penelitian ini adalah ditemukan 34 kata kunci yang terbagi dalam 9 cluster. Pada jejaring kepenulisan dari 1676 penulis dengan minimal jumlah 3 dokumen yang dipulikasikan, terdapat 33 penulis yang memenuhi batas minimum jejaring kepenulisan. Publikasi terbanyak terjadi pada tahun 2020 sebanyak 306 dalam Google Scholar.

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ปาสาจะ, ศิริกัญญา, i ปองภพ ภูจอมจิตร. "แนวทางการพัฒนาสถานศึกษาสู่องค์การแห่งนวัตกรรมการศึกษาสังกัดสำนักงานเขตพื้นที่การศึกษาประถมศึกษามหาสารคาม เขต 2". Interdisciplinary Academic and Research Journal 4, nr 2 (3.04.2024): 203–20. http://dx.doi.org/10.60027/iarj.2024.274642.

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ภูมิหลังและวัตถุประสงค์การวิจัย: การพัฒนาสถานศึกษาสู่องค์การแห่งนวัตกรรมการศึกษามีความสำคัญต่อคุณภาพการจัดการศึกษาที่มีคุณภาพ ภารกิจใหม่ของนักบริหารการศึกษาในยุคนวัตกรรมการศึกษาจึงต้องเพิ่มภารกิจทางด้านการจัดการนวัตกรรมหรือการบริหารนวัตกรรม เพื่อให้สอดคล้องกับความก้าวหน้าของแวดวงการศึกษา ดังนั้นการวิจัยครั้งนี้จึงมีวัตถุประสงค์เพื่อศึกษาสภาพปัจจุบัน สภาพที่พึงประสงค์และความต้องการจำเป็นการพัฒนาสถานศึกษาสู่องค์การแห่งนวัตกรรมการศึกษา และเพื่อศึกษาแนวทางการพัฒนาสถานศึกษาสู่องค์การแห่งนวัตกรรมการศึกษา สังกัดสำนักงานเขตพื้นที่การศึกษาประถมศึกษามหาสารคาม เขต 2 ระเบียบวิธีการวิจัย : การวิจัยแบ่งเป็น 2 ระยะ คือ ระยะที่ 1 ศึกษาสภาพปัจจุบัน สภาพที่พึงประสงค์ และความต้องการจำเป็นการพัฒนาสถานศึกษาสู่องค์การแห่งนวัตกรรมการศึกษา กลุ่มตัวอย่าง ได้แก่ ผู้บริหารสถานสึกษาและครู จำนวน 306 คน ได้มาโดยวิธีการสุ่มตัวอย่างแบบแบ่งชั้น เครื่องมือการวิจัย คือ แบบสอบถาม ลักษณะเป็นแบบมาตราส่วนประมาณค่า 5 ระดับ มีค่าความเชื่อมั่นเท่ากับ 0.94 วิเคราะห์ข้อมูลโดยการหาค่าร้อยละ ค่าเฉลี่ยและส่วนเบี่ยงเบนมาตรฐาน และระยะที่ 2 ศึกษาแนวทางการพัฒนาสถานศึกษาสู่องค์การแห่งนวัตกรรมการศึกษา กลุ่มเป้าหมาย ได้แก่ สถานศึกษาที่มีการปฏิบัติที่เป็นเลิศ จำนวน 3 แห่ง และผู้ทรงคุณวุฒิ จำนวน 9 คน เพื่อประเมินแนวทาง เครื่องมือการวิจัย คือ แบบสัมภาษณ์ และแบบประเมินความเหมาะสมและความเป็นไปได้ของแนวทาง ผลการวิจัย: สภาพปัจจุบันโดยรวมมีค่าเฉลี่ยอยู่ในระดับมาก สภาพที่พึงประสงค์โดยรวมมีค่าเฉลี่ยอยู่ในระดับมากที่สุด และมีค่าความต้องการจำเป็นเรียงตามลำดับจากค่าสูงสุดถึงต่ำสุด ดังนี้ 1) วัฒนธรรมขององค์การ 2) การพัฒนาบุคลากร 3) บรรยากาศนวัตกรรม 4) โครงสร้างองค์การ 5) การบริหารเชิงกลยุทธ์ ตามลำดับ 2. แนวทางการพัฒนาสถานศึกษาสู่องค์การแห่งนวัตกรรมการศึกษา สังกัดสำนักงานเขตพื้นที่การศึกษาประถมศึกษามหาสารคาม เขต 2 ประกอบด้วย 1) หลักการและเหตุผล 2) วัตถุประสงค์ 3) เนื้อหา 4) วิธีการพัฒนา และ 5) การวัดและประเมินผล โดยมีเนื้อหาการพัฒนาแบ่งเป็น 5 หน่วยการเรียนรู้ ดังนี้ 1) วัฒนธรรมขององค์การ 2) การพัฒนาบุคลากร 3) บรรยากาศนวัตกรรม 4) โครงสร้างองค์การ 5) การบริหารเชิงกลยุทธ์และมีผลการประเมินความเหมาะสมและความเป็นไปได้โดยรวมอยู่ในระดับมากที่สุด สรุปผล: การพัฒนาการบริหารสถานศึกษาสู่องค์การแห่งนวัตกรรมการศึกษามีความสำคัญต่อคุณภาพการบริหารสถานศึกษาและการจัดการศึกษาของสถานศึกษา นั่นเพราะองค์การแห่งนวัตกรรมนั้นเป็นองค์การที่มุ่งเน้นให้เกิดการสร้างนวัตกรรมในองค์การโดยมีการบริหารจัดการด้วยการริเริ่มสิ่งใหม่หรือการพัฒนาปรับปรุงวิธีการปฏิบัติ ประกอบด้วยองค์ประกอยที่สำคัญ ได้แก่ วัฒนธรรมขององค์การ การพัฒนาบุคลากร บรรยากาศนวัตกรรม โครงสร้างองค์การ และการบริหารเชิงกลยุทธ์

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Berkowitz, C. D. "Domestic Violence: A Pediatric Concern". Pediatrics in Review 25, nr 9 (1.09.2004): 306–11. http://dx.doi.org/10.1542/pir.25-9-306.

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Sabo-Graham, T., i A. R. Seay. "Consultation with the Specialist: Management of Status Epilepticus in Children". Pediatrics in Review 19, nr 9 (1.09.1998): 306–10. http://dx.doi.org/10.1542/pir.19-9-306.

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Da Silva Do Reis, Sírio Douglas, Marco Antonio Previdelli Orrico Junior, Michely Tomazi, Stéfane Souza Cunha, Ana Carolina Amorim Orrico, Joyce Pereira Alves i Edgar Salvador Jara Galeano. "Is organic fertilizer application a viable alternative to synthetic fertilizer for Piatã grass?" Tropical Grasslands-Forrajes Tropicales 9, nr 3 (30.09.2021): 300–306. http://dx.doi.org/10.17138/tgft(9)300-306.

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Organic fertilizer in many cases can replace mineral fertilizers and in consequence reduce production costs and improve soil quality. Thus, the aim of this work was to evaluate productive, morphogenic and structural characteristics of Piatã grass (Urochloa brizantha) fertilized with urea, organic compost and biofertilizer throughout a year. The trial design was a block split-plot in time (seasons) design with 4 treatments (fertilizing with urea, organic compost, biofertilizer and Control) and 6 repetitions. The evaluated parameters were: dry matter production (DMP), leaf elongation rate (LER), leaf appearance rate (LAR), phyllochron (PHYL), leaf lifespan (LLS), pseudostem elongation rate (SER), final leaf length (FLL), number of live leaves (NLL) and number of tillers (NT). The highest LAR values were observed during summer and spring for the treatment with urea, which also produced the highest LER values. No difference was found in SER among the fertilizer treatments but all fertilized treatments were superior to Control. NT and DMP values were highest (P<0.05) in the treatment with urea, followed by biofertilizer, organic compost and Control. In conclusion, while the use of urea provided greatest forage production, applying biofertilizer gave superior yields to organic compost. Other benefits of organic fertilizers should be assessed as well as combinations of organic and inorganic fertilizers.

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Taylor, Robert M., Todd C. Monson i Rama R. Gullapalli. "Influence of carbon chain length on the synthesis and yield of fatty amine-coated iron-platinum nanoparticles". Nanoscale Research Letters 9, nr 1 (2014): 306. http://dx.doi.org/10.1186/1556-276x-9-306.

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Kube, Michael, Bernd Schneider, Heiner Kuhl, Thomas Dandekar, Katja Heitmann, Alexander M. Migdoll, Richard Reinhardt i Erich Seemüller. "The linear chromosome of the plant-pathogenic mycoplasma 'Candidatus Phytoplasma mali'". BMC Genomics 9, nr 1 (2008): 306. http://dx.doi.org/10.1186/1471-2164-9-306.

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Brase, Jan C., Daniela Wuttig, Ruprecht Kuner i Holger Sültmann. "Serum microRNAs as non-invasive biomarkers for cancer". Molecular Cancer 9, nr 1 (2010): 306. http://dx.doi.org/10.1186/1476-4598-9-306.

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Harrison, David. "Nineteenth Century Lustreware99339Michael Gibson. Nineteenth Century Lustreware. Woodbridge: Antique Collectors’ Club 1999. 191 pp, ISBN: 1 85149 306 9 £45.00". Reference Reviews 13, nr 6 (czerwiec 1999): 40. http://dx.doi.org/10.1108/rr.1999.13.6.40.339.

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Liao, Po-Wei, Shao-Bin Cheng, Cheng-Wei Chou, Hsin-Chen Lin, Cheng-Hsien Lin, Tsung-Chih Chen, Chiann-Yi Hsu, Chieh-Lin Jerry Teng i Yu-Hsuan Shih. "Chemotherapy for Metastatic Gastric Cancer: Does Age Matter? A Single-Center, Retrospective, Real-World Study". Clinical Medicine Insights: Oncology 16 (styczeń 2022): 117955492211236. http://dx.doi.org/10.1177/11795549221123617.

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Background: Palliative chemotherapy is the preferred standard of care for patients with metastatic gastric cancer (mGC). It remains uncertain whether older patients with mGC would benefit from palliative chemotherapy. This study aimed to investigate the clinical impact of palliative chemotherapy in older patients with mGC. Methods: This single-institute, retrospective, and real-world study included 428 patients with mGC between January 2009 and December 2019. Among them, 306 who received palliative chemotherapy were further stratified into 2 groups according to age: ≤70 (n = 236) and >70 (n = 70) years. The clinical demographics, outcomes, and hematologic toxicities of chemotherapy were compared between the 2 groups. Prognostic factors were determined using the Cox proportional hazards model. Results: Of the screened 428 patients, older patients had worse overall survival (OS) than younger patients. Among patients who received chemotherapy (n = 306), patients aged >70 and ⩽70 years had comparable progression-free survival (PFS) and OS. The incidence of severe hematologic toxicity was similar between the 2 groups. The Eastern Cooperative Oncology Group performance status of 2 or more metastatic sites, elevated carbohydrate antigen 19-9 level, high neutrophil-to-lymphocyte ratio (NLR), and undergoing palliative gastrectomy were independent prognostic factors for OS. Notably, age >70 years was not a significant factor for poor OS. Conclusions: Older age of >70 years might not be considered an obstacle to administering palliative chemotherapy to patients with mGC.

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Poenaru, D. N., i R. A. Gherghescu. "Cluster Radioactivity". Journal of Nuclear Physics, Material Sciences, Radiation and Applications 8, nr 1 (19.11.2020): 65–71. http://dx.doi.org/10.15415/jnp.2020.81008.

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Cluster radioactivity (spontaneous emission of heavy particles from nuclei) is presented from theoretical point of view in good agreement with experimental results. After a brief hystorical account we give details about the analytical super asymmetric fission (ASAF) model extensively used for predicting the half-lives of heavy and superheavy (Z ≥ 104) elements. For the already measured 26 cluster decays (from 14C to 32,34Si of parent nuclides with Z = 87-96) it is clear that cluster radioactivity is a rare phenomenon in the best case about 9 orders of magnitude weaker than the competing alpha decay. Then we show the theoretical possibility of a strong cluster decay compared to alpha decay for some superheavy nuclei with Z ≥ 122, e.g. 306122; 310-314122; 306-324124, and 311-323124.

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Anak Agung Gde Krisna Paramita, Dewa Nyoman Arsana i Dewa Ayu Kade Linda Dewi. "INTERNALISASI NILAI KARAKTER HINDU DALAM AJARAN PRADNYAN DAN PURUSOTTAMA". Vidyottama Sanatana: International Journal of Hindu Science and Religious Studies 7, nr 2 (31.10.2023): 227–34. http://dx.doi.org/10.25078/vidyottama.v7i2.2494.

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Penelitian ini mengkaji suatu konsep dalam ajaran internalisasi nilai karakter Hindu yang termuat dalam ajaran Pradnyan dan Purusottama, sebagai objek utama yakni Manusia Hindu yang berkarakter sesuai konsep ajaran Pradnyan dan Purusottama. Penelitian menggunakan metode kualitatif yang berbasis data dalam bentuk naratif kajian teks. Adapun deskripsi penelitian ini yakni Nilai Karakter dalam ajaran Pradnyan dan Purusottama dalam kitab sarasamuccaya sloka (304-306), yakni karakter manusia Hindu : 1. Tan girang yan inalem, 2. Tan alara yan inida, 3. Tan kataman krodha, 4. Tan ujarakenang sawacana, 5. Langgeng dhiraning manah, 6. Taranggenangen dosaning len, 7. Tan ujarakenang parapawada, 8. Guna rahayu kenget nira, 9. Apageh ri maryadanira, konsep ini adalah Nawa Purusottama yakni Sembilan laksana manusia utama dalam konsep Hindu yang wajib dimiliki dan diimplementasikan dalam kehidupan beragama sosial.

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Reglinski, J. "Resonance studies Biological Magnetic Resonance, Volume 9, edited by L.J. Berliner and J. Reuben, Plenum, New York, 1990, US$ 65.00 (v + 251 pages), ISBN: 0-306-43341-9". TrAC Trends in Analytical Chemistry 10, nr 2 (luty 1991): x. http://dx.doi.org/10.1016/0165-9936(91)85112-5.

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HASANJANI ROUSHAN, M. R., M. MOHREZ, S. M. SMAILNEJAD GANGI, M. J. SOLEIMANI AMIRI i M. HAJIAHMADI. "Epidemiological features and clinical manifestations in 469 adult patients with brucellosis in Babol, Northern Iran". Epidemiology and Infection 132, nr 6 (16.11.2004): 1109–14. http://dx.doi.org/10.1017/s0950268804002833.

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The epidemiological features and clinical manifestations of adult cases of brucellosis admitted to the Department of Infectious Diseases, Babol Medical University, Iran from 1997 to 2002 were investigated. Of 469 cases, 267 (56·9%) were males. The mean age of cases was 36·9±15 years. Most (60·8%) were from rural areas. Two thirds of cases (306, 66·3%) presented during spring or summer. Fresh cheese (22·4%), animal husbandry (11·3%), laboratory worker (8·1%) and veterinary profession (1·5%) were the main risk factors. Forty-five families (9·6%) had two cases. Sweating, fever, and arthralgia were the most frequent clinical symptoms. Complications were documented in 105 males (39·5%) and 41 females (20·3%, P=0·0001). Peripheral arthritis was seen in 24 (9%) males and 19 (9·4%) females, with knees and hips being the most common sites of infection. Sacroiliitis and spondylitis were seen in 28 (6%) and 32 (6·8%) cases respectively with spondylitis more common in males (P=0·023). Epididymo-orchitis was seen in 29 (10·9%) males. There were three cases each of endocarditis (0·6%) and neurological complications (0·6%). Most patients with brucellosis did not have any of the known risk factors for brucellosis. Thus consumption of unsafe dairy products could be the main route of infection. The disease manifested with a diversity of clinical manifestations and complications. Complications were more frequent in males than females.

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Tye, Diane. "Culinary Tourism. By Lucy M. Long, ed. (Lexington: University Press of Kentucky, 2004. Pp. xiv + 306, ISBN 0-8131-2292-9)". Ethnologies 28, nr 2 (2006): 229. http://dx.doi.org/10.7202/014992ar.

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Negro, Jesse. "Democratic Eco‐Socialism as a Real UtopiaH. A.BaerBerghahn Books, 2018. Pp. vi + 306, £85.00 (Hc.), ISBN 978‐1‐78533‐695‐9." Australian Journal of Anthropology 30, nr 3 (23.07.2019): 336–37. http://dx.doi.org/10.1111/taja.12329.

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Maclellan, Effie. "Mathematics Explained for Primary Teachers, Derek Haylock (London: Paul Chapman Publishing, 2001) ISBN: 0-7619-6951-9 (pp. 306; £18.99 paperback.)". Scottish Educational Review 35, nr 1 (9.01.2003): 79–80. http://dx.doi.org/10.1163/27730840-03501010.

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Kosia Mokoro, Daniel. "Perception of Teachers on their Preparedness for Implementation of the Competence-based Curriculum among Secondary Schools in Arumeru District, Tanzania". July to September 2020 1, nr 2 (6.08.2020): 109–17. http://dx.doi.org/10.46606/eajess2020v01i02.0026.

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The purpose of this study was to find out the extent to which implementation of competence-based curriculum (CBC) is adequately supported by laboratory facilities among public secondary schools in Arumeru District, Tanzania, using a convergent parallel mixed design. Stratified-random sampling technique was used to select students and teachers whereas purposive sampling technique was used to select heads of schools and academic masters/mistresses. Consequently, the sample included 111 teachers, 177 students, 9 heads of schools and 9 academic masters/ mistresses making a total sample size of 306 respondents. Data were collected using questionnaires, interview guide, observation checklist and focus group discussion (FGD) guide and analyzed through descriptive statistics and thematic analysis. It was found that only 34% of the teachers were trained while 66% were not trained for CBC implementation. The study concluded that, the implementation of CBC is rendered ineffective due to lack of teacher training. The study recommended that the Ministry of Education, Science and Technology in collaboration with curriculum developers should organize training to all teachers for effective implementation of CBC.

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GUNNLAUGSSON, G., J. EINARSDÓTTIR, F. J. ANGULO, S. A. MENTAMBANAR, A. PASSA i R. V. TAUXE. "Funerals during the 1994 cholera epidemic in Guinea-Bissau, West Africa: The need for disinfection of bodies of persons dying of cholera". Epidemiology and Infection 120, nr 1 (luty 1998): 7–15. http://dx.doi.org/10.1017/s0950268897008170.

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The 1994 cholera epidemic in Guinea-Bissau resulted in 15878 reported cases and 306 deaths. Early in the epidemic, although the health ministry mandated that the bodies of persons dying of cholera be disinfected, outbreaks occurred in several villages following funerals in the region of Biombo. To determine the influence of disinfection and funeral activities on cholera transmission, we analysed surveillance data and conducted a case-control study following a funeral. The attack rate during the week following funerals was higher in villages where bodies were not disinfected (risk ratio = 2·6, 95% confidence interval [CI] 1·9–3·8). Cholera was strongly associated with eating at a funeral with a non-disinfected corpse (odds ratio [OR] = 14·5, 95% CI 0·9–786) and with touching (i.e., transporting, washing) the body (OR = 36·2, 95% CI 2·6–1769). During cholera epidemics, in addition to other cholera prevention activities, health officials should inform community leaders about the risk of cholera transmission during funerals, meals should not be served at funerals, and bodies of persons dying of cholera should be disinfected.

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Córdoba, Liliana, Jharley Jair García, Luz Stella Hoyos, Constanza Duque, Winston Rojas, Silvio Carvajal, Luisa Fernanda Escobar i in. "Composición genética de una población del suroccidente de Colombia". Revista Colombiana de Antropología 48, nr 1 (30.06.2012): 21–48. http://dx.doi.org/10.22380/2539472x.879.

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La población actual del departamento del Cauca es el resultado de la mezcla de tres poblaciones parentales (europea, amerindia y africana). En este estudio se determinó la composición genética de 306 residentes del departamento mediante la utilización de 34 variantes autosómicas, 9 variantes en el cromosoma X, 6 en el ADNmt y 8 en el cromosoma Y. Los análisis de las variantes autosómicas y del cromosoma X revelaron que la población europea y la amerindia han contribuido en mayor proporción al actual acervo genético de la población estudiada. Los resultados de las variantes en el ADNmt y del cromosoma Y sugieren un fuerte sesgo sexual (flujo génico asimétrico) en el proceso de mezcla, en el que los cruces interétnicos fueron principalmente entre los colonizadores europeos y las mujeres nativas.

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Ciubotaru, Mihail, Florin Leuciuc i Gheorghe Pricop. "Analysis of Student Opinions on the Motivation of Physical Education Lessons". GYMNASIUM XX, nr 2 (31.12.2019): 124. http://dx.doi.org/10.29081/gsjesh.2019.20.2.10.

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The motivation assessment regarding the attendance of physical education classes was known by the survey of 652 students from the secondary school, 345 boys and 306 girls. We used the motivation study survey, where the questionnaire contained 9 questions regarding the activity within the physical education classes and 3 questions containing information about the students. After investigating the students we can say that most are motivated to come to school, participate actively in physical education, are not happy if the lesson is canceled, over 50% sometimes talk to parents about the activity, they do not want another teacher at class, he practices different sports, especially handball and football, besides they want to introduce tennis, and he does not attend physical education and sports classes to diminish the general success or avoid absences.

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Nur, Andi Sofyan, Misnawaty Usman i Nurming Saleh. "Model Pembelajaran Tipe Complete Sentence Dalam Penguasaan Kosakata Bahasa Jerman". Phonologie : Journal of Language and Literature 1, nr 2 (20.06.2021): 49. http://dx.doi.org/10.26858/phonologie.v1i2.21515.

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Abstract. The aim of this research is to examine the effectives cooperative learning model type complete sentence in mastering German vocabulary of students XI class at SMA Negeri 14 Gowa. This research is Quasi-experimental reasearch. The data was collected by reading comprehension test and was analyzed by using t-test. Population of this research was 306 students from 9 class. Sampel was selected by using simple random sampling where XI IPA 4 class with 36 students as experimental class and XI IPA 5 class with 35 students as control class. The result showed t-count is higher that t-table (t-count4,87 > t-table 1,997) with alpha significant level 0,05. It revealed that cooperative learning model type complete sentence is effective in mastering German vocabulary of XI students at SMA 14 Gowa.

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Bradford, Kent J. "Seeds: physiology of development and germination J. D. Bewley and M. Black, xv + 445 pp. Second Edition. Plenum Press, New York, London, 1994. ISBN 0-306-44747-9 (hardbound) $75.00. ISBN 0-306-44748-7 (paperback) $39.50". Seed Science Research 5, nr 2 (czerwiec 1995): 127–28. http://dx.doi.org/10.1017/s0960258500002713.

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Petrovic, Milenko, Esther Park, Amanda Pangle, Jeanne Wei i Gohar Azhar. "ASSESSMENT OF ELECTROLYTE ABNORMALITIES IN OLDER ADULTS WITH COVID-19 DELIRIUM". Innovation in Aging 7, Supplement_1 (1.12.2023): 991. http://dx.doi.org/10.1093/geroni/igad104.3186.

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Abstract This retrospective study explored the impact of COVID-19 on altered sodium and potassium in older adults with delirium. EMRs from the University of Arkansas for Medical Sciences (UAMS) database were reviewed from January 7, 2018 to January 5, 2021 for electrolyte abnormalities and delirium. Inclusion criteria were age 65 or older, all races, genders, and ethnicities with COVID or non-COVID infections. We identified 319 patients with COVID-19 out of which 108 (33.8%) had delirium during COVID. In COVID-delirious patients, hypokalemia was present in 8, hyperkalemia in 10, hyponatremia in 9, and hypernatremia in 20.127/319 (39.8%) COVID patients had an electrolyte disorder at some point with hypokalemia being most represented at 58/127 (45.7%). Out of the patients who experienced hypokalemia at some point, 34/319 (10.6%) had delirium. In another cohort of 306 older adults with non-COVID pneumonias we identified 173 patients with electrolyte disorders and 106 (34.6%) with delirium during pneumonia. Electrolyte disturbances were more present in non-COVID pneumonias vs. those with COVID (p< 0.001). Hypokalemia was more identified in non-COVID, 56/306 (18.3%), vs. COVID patients, 34/319 (10.6%) (p< 0.006). Interestingly, hypernatremia was greater in COVID groups (p< 0.0321). There was no difference in delirium between COVID vs non-COVID patients, but electrolytes disorders and hypokalemia were observed with greater frequency in non-COVID pneumonias. Notably, hypernatremia developed more in patients suffering from COVID and since it can be associated with seizures and cerebral hemorrhage, particular attention should be paid to prevent hypernatremia from developing in order to reduce COVID-related morbidity and mortality.

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Kosia Mokoro, Daniel. "Adequacy of Laboratory Facilities for Effective Implementation of Competence-Based Curriculum in Public Secondary Schools in Arumeru District, Tanzania". July to September 2020 1, nr 2 (19.08.2020): 141–49. http://dx.doi.org/10.46606/eajess2020v01i02.0029.

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The purpose of this study was to find out the extent to which implementation of competence based curriculum (CBC) is adequately supported by laboratory facilities in public secondary schools in Arumeru District in Tanzania. Convergent parallel mixed method design was applied in the study. The study sampled 111 teachers, 177 students, 9 head of schools and 9 academic masters/mistresses making a total sample size of 306 respondents. Stratified-random sampling technique was used to select students and teachers whereas a purposive sampling technique was used to select heads of schools and academic masters/mistresses. Data were collected using questionnaires, interview guide, observation checklist and focus group discussion (FGD) guide. Data analysis was done using descriptive statistics and thematic analysis. The study established that, laboratory facilities were not adequate in the schools hence it was concluded that, the competence-based curriculum is not effectively implemented in the studied schools due to shortage of laboratory facilities. It was therefore recommended that the government in collaboration with other educational stakeholders should establish the required laboratory facilities for effective implementation of the competence- based in the schools.

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Hellhammer, Katharina, Jean M. Haurand, Maximilian Spieker, Peter Luedike, Tienush Rassaf, Tobias Zeus, Malte Kelm, Ralf Westenfeld i Patrick Horn. "Predictors of functional mitral regurgitation recurrence after percutaneous mitral valve repair". Heart and Vessels 36, nr 10 (3.04.2021): 1574–83. http://dx.doi.org/10.1007/s00380-021-01828-9.

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AbstractWe aimed to identify predictors of mitral regurgitation recurrence (MR) after percutaneous mitral valve repair (PMVR) in patients with functional mitral regurgitation (FMR). Patients with FMR were enrolled who underwent PMVR using the MitraClip® device. Procedural success was defined as reduction of MR of at least one grade to MR grade ≤ 2 + assessed at discharge. Recurrence of MR was defined as MR grade 3 + or worse at one year after initially successful PMVR. A total of 306 patients with FMR underwent PMVR procedure. In 279 out of 306 patients (91.2%), PMVR was successfully performed with MR grade ≤ 2 + at discharge. In 11.4% of these patients, MR recurrence of initial successful PMVR after 1 year was observed. Recurrence of MR was associated with a higher rate of heart failure rehospitalization during the 12 months follow-up (52.0% vs. 30.3%; p = 0.029), and less improvement in New York Heart Association (NYHA) functional class [68% vs. 19% of the patients presenting with NYHA functional class III or IV one year after PMVR when compared to patients without recurrence (p = 0.001)]. Patients with MR recurrence were characterized by a higher left ventricular sphericity index {0.69 [Interquartile range (IQR) 0.64, 0.74] vs. 0.65 (IQR 0.58, 0.70), p = 0.003}, a larger left atrium volume [118 (IQR 96, 143) ml vs. 102 (IQR 84, 123) ml, p = 0.019], a larger tenting height 10 (IQR 9, 13) mm vs. 8 (IQR 7, 11) mm (p = 0.047), and a larger mitral valve annulus [41 (IQR 38, 43) mm vs. 39 (IQR 36, 40) mm, p = 0.015] when compared to patients with durable optimal long-term results. In a multivariate regression model, the left ventricular sphericity index [Odds Ratio (OR) 1.120, 95% Confidence Interval (CI) 1.039–1.413, p = 0.003)], tenting height (OR 1.207, 95% CI 1.031–1.413, p = 0.019), and left atrium enlargement (OR 1.018, 95% CI 1.000–1.038, p = 0.047) were predictors for MR recurrence after 1 year. In patients with FMR, baseline parameters of advanced heart failure such as spherical ventricle, tenting height and a large left atrium might indicate risk of recurrent MR one year after PMVR.

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Fadl, Shehella Rsul. "Prevalence of Parasitic Infection in Sheep From different Regions in Baghdad". Iraqi Journal of Veterinary Medicine 35, nr 1 (29.06.2011): 204–9. http://dx.doi.org/10.30539/iraqijvm.v35i1.625.

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This research concerns (306)faecal samples from different regions in Baghdad from sheep were examined,the results showed that 230 samples were infected with gastrointestinal parasites with total rate 75.1% which included : 49.0% of coccidiosis ( 9 species of Eimeria were recorded E.parva, E.ovina, E.crandalli s, E. weybridgensi, E. pallida, E. granulosa E .faurei, E. ovinadalis E.marsica) , 21.2% Nematodes 7.84% ,6.5% ,4.5%, 2.2% for Haemonchus, Trichostrongylus ,Nematodiru,and Trichuris in respectively , while the percentage of trematodes & cestodes infections were 4.9% for fasciola 2.28% , Paramphistomum 1.6% , Moniezia 0.9% .Age factor influenced on infection percentage it is higher in younger with coccidiosis infection 25.4% while it is higher in aged animals with nematodes% 10.13 & 1.96% for trematodes & cestodes. Prevalence of coccidiosis infection showed seasonal diversity it is higher in winter, while the rate of infection with nematodes & trematodes is higher in summer & lowers in winter.

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Kafle, D., M. Humagain i C. Upadhaya. "Adjunctive Orthodontic Treatment with Lingual Orthodontic System". Kathmandu University Medical Journal 9, nr 4 (18.06.2012): 306–9. http://dx.doi.org/10.3126/kumj.v9i4.6351.

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The lingual orthodontic therapy though started in 1972, could not be popular till the beginning of 1990. In Nepal it does not have a history of more than a year. It is started in Dhulikhel Hospital for the first time in Nepal. Usually orthodontic therapy is meant for putting braces on the labial surface of the teeth which is called labial orthodontic system. Lingual orthodontic system is a purely invisible kind of orthodontic therapy in which braces are placed behind the teeth. The advantages of lingual orthodontic therapy are: invisibility, better biomechanics and improved patient compliance. On the other hand it is difficult to master and costlier than labial orthodontics. We have presented six adjunctive orthodontic cases treated by lingual system with the same end result comparable to labial orthodontic system. DOI: http://dx.doi.org/10.3126/kumj.v9i4.6351 Kathmandu Univ Med J 2011;9(4):306-9

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