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Concha, Villanueva Sebastian. "Mitologías de Ni por mar ni por tierra y Quién llama en los hielos de Miguel Serrano : hacia una utopía sin cultura de masas". Tesis, Universidad de Chile, 2014. http://repositorio.uchile.cl/handle/2250/116160.
Pełny tekst źródłaMangiola, Zapata Paula. "Las décimas de Violeta Parra: identidad y canto popular". Tesis, Universidad de Chile, 2015. http://repositorio.uchile.cl/handle/2250/138592.
Pełny tekst źródłaVioleta Parra es una de las artistas chilenas más reconocidas, ella incursionó en diversas manifestaciones creativas como la música, el tejido de arpilleras y la escritura de poesía. Así también trabajó arduamente en la recopilación del folclor popular, y por eso su obra es relevante tanto nacional como internacionalmente, ya que logró además posicionar y hacer reconocible a Chile en el extranjero. Las Décimas, escritas entre 1957 y 1958, relatan la historia de vida de la autora, sus penas y alegrías, usando la poesía con un modo propio que cuestiona el canon y las reglas literarias. Es un ejercicio autobiográfico de memoria, identificación y liberación personal, que se acerca a la tradición lírica culta y al mismo tiempo la transgrede, incorporando la musicalidad y el conocimiento popular. En el texto Violeta crea un relato que abarca su infancia, juventud y adultez cimentado en múltiples rostros propios y ajenos, individuales y colectivos. Instala su poética en la frontera entre lo oral y lo escrito, entre lo ético y lo estético, expresando el desagarro y las penurias personales y universales mediante la música y la escritura. Se estudiarán a continuación las Décimas desde sus antecedentes histórico-literarios y contexto de creación y publicación, además se revisará la búsqueda íntima de la autora sobre su identidad, rol como artista e ideología político social. Como base teórico literaria se estudiarán los fundamentos de la autobiografía y de la lira popular, y en el caso del género los conceptos de abyección, cuerpo fragmentado y performance.
Webler, Meike. "Leben und Werk des Heidelberger Rechtslehrers Richard Carl Heinrich Schroeder (1838 - 1917) : ein Rechtshistoriker an der Schwelle vom 19. zum 20. Jahrhundert /". Berlin : Duncker & Humblot, 2005. http://www.gbv.de/dms/spk/sbb/recht/toc/497945894.pdf.
Pełny tekst źródłaSanhueza, A. Gonzalo. "En torno al sujeto Gómez Morel". Tesis, Universidad de Chile, 2011. http://repositorio.uchile.cl/handle/2250/108721.
Pełny tekst źródłaDrunkenmölle, Tomas Rodolfo. "O significado das metáforas segundo Searle e Davidson / Tomas Rodolfo Drunkenmölle ; orientador, Kleber B. B. Candiotto". reponame:Biblioteca Digital de Teses e Dissertações da PUC_PR, 2011. http://www.biblioteca.pucpr.br/pergamum/biblioteca/img.php?arquivo=/000051/0000513d.pdf.
Pełny tekst źródłaBibliografia: f. 108-110
As abordagens da metáfora de Donald Davidson e John Searle são consistentes com as respectivas teorias do significado nas quais estão baseadas. Enquanto ambos os filósofos concordam que a falsidade patente geralmente se evidencia nos casos em que a metáf
Donald Davidson's and John Searle's approach to metaphor is consistent with their respective theory of meaning on which it is based. While both philosophers agree that patent falsity is the usual case with metaphor in their literal interpretation, they di
Salazar, Poblete Francisca. "La búsqueda de la trascendencia en Contra la muerte de Gonzalo Rojas: una lectura desde el origen". Tesis, Universidad de Chile, 2017. http://repositorio.uchile.cl/handle/2250/147175.
Pełny tekst źródłaLa presente lectura de Contra la muerte (1964) de Gonzalo Rojas tiene como principal objetivo, a partir de una metodología no biografista, ahondar en los diferentes modos que el poemario propone para buscar la trascendencia. Para ello, se comenzó por el análisis de “El sol es la única semilla”, poema clave para encontrar estos medios de sobrevivir a la muerte, que en el orden de los capítulos resultan ser los siguientes: a través de la mujer y el encuentro sexual; a través de la reproducción; a través de la disolución del sujeto en la comunidad; y, por último, a través del lenguaje mismo. El camino escogido fue realmente efectivo, pues el poema central demostró dar cuenta de diferentes modos de trascendencia que, en diálogo con el resto de los poemas, evidenciaron la coherencia global de Contra la muerte, tejida principalmente por el símbolo del sol como experiencia del tiempo cíclico, y por las ansias del sujeto poético de alcanzar lo absoluto y regresar al origen, aventura que resulta en fracaso pues siempre encuentra como límite la condición mortal. Esto, sin embargo, no impide que el hablante tenga acercamientos a lo trascendente, que resultan ser solo destellos en su búsqueda incesante.
Webler, Meike [Verfasser]. "Leben und Werk des Heidelberger Rechtslehrers Richard Carl Heinrich Schroeder (1838 - 1917). : Ein Rechtshistoriker an der Schwelle vom 19. zum 20. Jahrhundert. / Meike Webler". Berlin : Duncker & Humblot, 2011. http://d-nb.info/1238350658/34.
Pełny tekst źródłaPeña, Contreras Yeisil Carolina. "London as a corpse in Anthony Burgess' The doctor is sick". Tesis, Universidad de Chile, 2013. http://www.repositorio.uchile.cl/handle/2250/115673.
Pełny tekst źródłaThe aim of the present work is to demonstrate that The Doctor is Sick sets out the way in which the subject abandons the institutionalized boundaries of the sign, understood under the structuralism constraints, and discovers a New World characterized by the sign deconstruction. The analogy for that purpose is an Old World that functions as a living body machine, and a New World that is unstable, infinite and subject-dependent; characterized as an anti-hegemonic corpse. As a patient/doctor, the subject dissects what was unknown and invisible by providing an anatomical reading of his lethargic route.
Contreras, Godoy Loreto. "Producir poéticamente la historia: sobre Yo el supremo de Augusto Roa Bastos". Tesis, Universidad de Chile, 2015. http://repositorio.uchile.cl/handle/2250/136585.
Pełny tekst źródłaRamos, Rodillo Ignacio Alejandro. "Políticas del folklore: representaciones de la tradición y lo popular : militancia y política cultural en Violeta Parra y Atahualpa Yupanqui". Tesis, Universidad de Chile, 2012. http://www.repositorio.uchile.cl/handle/2250/113782.
Pełny tekst źródłaLa dimensión social de la música en América Latina ya es un área de estudios que las disciplinas artísticas, científico sociales y humanísticas se han dedicado a indagar y legitimar desde hace por lo menos treinta años. Estos intereses han conformado una extensa producción académica, investigativa y ensayística que considera lo musical no sólo como un reflejo o una consecuencia de la estructura y devenir de nuestras sociedades, sino que constituyen ámbitos de significación y producción simbólica donde las mismas dinámicas sociales se ven construidas y transformadas constantemente por los fenómenos ligados a las prácticas y recepciones de la música. Es todo mi interés afrontar la puesta en escrito de una inquietud investigativa que cumple con las obligaciones impuestas por el Programa de Magíster en Estudios Latinoamericanos del Centro de Estudios Culturales Latinoamericanos de la Universidad de Chile, concluyendo tres años de estudio y trabajo en torno de distintos aspectos de la dimensión cultural de América Latina. Y asimismo, responde a un interés personalísimo, por el cual intento a todas luces otorgarle un estatus académico a la profunda fascinación que en mí la música ha concitado desde la infancia. Entonces, la tesis que el lector en adelante tendrá ocasión de leer es fruto de mi proceso personal de producción cognoscitiva, cuyas fuentes son tanto la pasión particular como la reflexión y la investigación académicas. Hacia el primer semestre del año 2010 decidí enfocar mi trabajo en dos figuras latinoamericanas cruciales para la cultura del siglo XX, a saber, la chilena Violeta Parra Sandoval y el argentino Atahualpa Yupanqui.
Figueroa, Gallardo Natalia. "Eduardo Anguita, Braulio Arenas y Miguel Serrano: tres escritores a contracorriente". Tesis, Universidad de Chile, 2014. http://repositorio.uchile.cl/handle/2250/140652.
Pełny tekst źródłaŠemíková, Petra. "Stanislav Sucharda – fotografie a socha". Master's thesis, Akademie múzických umění v Praze.Filmová a televizní fakulta. Knihovna, 2018. http://www.nusl.cz/ntk/nusl-391687.
Pełny tekst źródłaMiranda, Herrera Paula. "Identidad nacional y poéticas identitarias: Gabriela Mistral - Vicente Huidobro - Pablo Neruda - Violeta Parra : (1912-1967)". Tesis, Universidad de Chile, 2005. http://www.repositorio.uchile.cl/handle/2250/108865.
Pełny tekst źródłaEn este trabajo se estudian cuatro obras poéticas pertenecientes a la poesía chilena de la primera mitad del siglo XX para establecer la forma en que se configuran allí las tematizaciones y textualizaciones de la identidad nacional chilena en relación directa con los contextos sociales y discursivos en los que fueron producidas. Se revisa así la obra de Gabriela Mistral, Vicente Huidobro, Pablo Neruda y Violeta Parra, en el periodo comprendido entre 1912 y 1967.
Pethel, Mary Ellen. "Athens of the South: College Life in Nashville, A New South City, 1897-1917". Digital Archive @ GSU, 2008. http://digitalarchive.gsu.edu/history_diss/20.
Pełny tekst źródłaКостогрызов, П. И. "Антибольшевистское движение на Урале в 1917 – 1918 г. : автореф. дис. … канд. ист. наук : 07.00.02". Thesis, б. и, 2013. http://hdl.handle.net/10995/20706.
Pełny tekst źródłaБулавин, М. В. "Взаимоотношения государственной власти и православной церкви в России в 1917 - 1927 гг. (на примере Урала) : Автореф. дис. ... канд. ист. наук: 07.00.02". Thesis, Изд-во Урал. гос. ун-та, 2000. http://hdl.handle.net/10995/616.
Pełny tekst źródłaAnzolin, Heloisa Helena. "Universidade e conhecimento : biblioteca universitária como centro difusor na história e suas contribuições para a atuação do professor como pesquisador e docente / Heloisa Helena Anzolin ; orientadora, Rosa Lydia Teixeira Corrêa". reponame:Biblioteca Digital de Teses e Dissertações da PUC_PR, 2008. http://www.biblioteca.pucpr.br/tede/tde_busca/arquivo.php?codArquivo=1917.
Pełny tekst źródłaBibliografia: f. 105-111
A investigação teve como objeto de pesquisa Universidade e conhecimento: biblioteca universitária com centro difusor na história e suas contribuições para a atuação do professor como pesquisador e docente. Teve como fio condutor o objetivo de analisar de
The investigation's research target was University and Knowledge: the university library as a broadcasting center in history and its contributions to the work of the professor as a researcher and faculty member. The core goal was to analyze how the Centra
Zduniak, Maria. "Novitäten im Breslauer Stadttheater: Richard Strauss - Salome (1906), Claudio Monteverdi - L''Orfeo (1913), Ludomir Różycki Eros und Psyche (1917)". Musikgeschichte in Mittel- und Osteuropa ; 3 (1998), S. 136-145, 1998. https://ul.qucosa.de/id/qucosa%3A15459.
Pełny tekst źródłaМасютин, А. С. "Эволюция деятельности организаций партии социалистов-революционеров в Вятской губернии (1896 – начало 1917 гг.) : диссертация на соискание ученой степени кандидата исторических наук : 07.00.02". Thesis, б. и, 2019. http://hdl.handle.net/10995/68400.
Pełny tekst źródłaМасютин, А. С. "Эволюция деятельности организаций партии социалистов-революционеров в Вятской губернии (1896 – начало 1917 гг.) : автореферат диссертации на соискание ученой степени кандидата исторических наук : 07.00.02". Thesis, б. и, 2019. http://hdl.handle.net/10995/68399.
Pełny tekst źródłaБаженова, К. Е. "Деятельность организаций Всероссийского Земского союза и Всероссийского Союза Городов на Среднем Урале в годы Первой мировой войны (1914-февраль 1917) : автореф. дис. … канд. ист. наук : 07.00.02". Thesis, б. и, 2010. http://hdl.handle.net/10995/3051.
Pełny tekst źródłaFišerová, Hana. "Jaroslav Špillar (1869-1917) a český výtvarný folklorismus na přelomu 19. a 20. století". Master's thesis, 2012. http://www.nusl.cz/ntk/nusl-308240.
Pełny tekst źródłaMachado, Susana Maria Norte Saraiva. "A arquitectura romanesca em Portagem, de Orlando Mendes". Master's thesis, 2009. http://hdl.handle.net/10451/408.
Pełny tekst źródłaUma análise aprofundada do romance Portagem, de Orlando Mendes, auxiliada por um conjunto de textos do Autor publicados em jornais das décadas de quarenta, cinquenta e sessenta, pode conduzir-nos a uma nova abordagem na leitura do texto, dos valores veiculados e dos pressupostos ideológicos inerentes a uma estética realista. Influenciado pelo Neo-Realismo português e pelo romance social americano das décadas de 1920 e 1930, o autor define um projecto, no qual expõe as dificuldades vividas pelo protagonista, o mulato João Xilim, numa sociedade colonial, que se sente marginalizado e discriminado por brancos e negros, vítima da desconfiança de ambas as raças. As dúvidas quanto à dualidade da personagem levam o protagonista a encetar uma busca pela afirmação da sua identidade, que coincide com uma série de obstáculos e de encontros com outras personagens, que lhe vão permitir um crescimento interior e uma consciencialização do seu papel naquela sociedade. O momento da afirmação plena da sua opção, a opção de ser negro, com o reconhecimento dos outros, acontece na cadeia quando toma partido dos negros. Cumpre-se, assim, o pagamento da portagem . A partir deste momento, a personagem está em condições de se tornar num indivíduo consciente, embora ainda necessite de outras aprendizagens, mas capaz de passar à luta colectiva. No processo de composição do enredo, em momentos descritivos que antecedem situações problemáticas, o Autor utiliza procedimentos formais que o aproximam do romance social americano, em especial de As Vinhas da Ira, de John Steinbeck, ao deixar transparecer a técnica cinematográfica e o afastamento do narrador, convocando o efeito de real. Contudo, este projecto é também um romance de tese, na medida em que é escrito com o propósito de fazer a apologia da mestiçagem cultural e racial e igualmente propor uma nova sociedade baseada na síntese dos valores ancestrais da África tradicional e da mensagem de fraternidade do Novo Humanismo.
A deep analysis of the novel Portagem, by Orlando Mendes, helped by a set of texts of the Author published in newspapers of the 1940s, 1950s and 1960s, may lead us to a new reading approach of the text, of the values expressed and the ideological assumptions inherent to a realistic aesthetics. Influenced by the Portuguese Neo-Realism and by the American social novel of the 1920s and 1930s, the Author defines a project, in which he exposes the difficulties lived by the main character, the bi-racial João Xilim, in a colonial society, that feels marginalized and discriminated by whites and blacks, victim of the mistrust of both races. The doubts related to the duality of the character, leads him to a quest for the statement of his identity, which coincides to a series of obstacles and meetings with other characters, allowing his interior growth and a consciousness of his role in that society. The moment of the full statement of his option, the option of being black, recognized by the others, happens while in jail, when he chooses the blacks. The payment of the toll is accomplished. In the process of composing the plot, in descriptive moments that happen before problematic situations, the Author uses formal procedures that bring it close to the American social novel, especially to The Grapes of Wrath, by John Steinbeck, showing a cinematographic technique and the moving away of the narrator, which brings the real effect. However, this project is also a thesis novel, as it was written with the purpose of making the apology of bi-racialism and biculturalism and proposing a new society based on the synthesis of the ancient values of traditional Africa and the message of fraternity and solidarity of the New Humanism.
Canales, Cabezas Reiner. "De los cantos folklóricos chilenos a las décimas: trayectoria de una utopía en Violeta Parra". Tesis, 2005. http://www.repositorio.uchile.cl/handle/2250/108868.
Pełny tekst źródłaEn esta tesis relacionamos dos libros de Violeta Parra: Cantos Folklóricos Chilenos y Décimas, por medio de los conceptos de carnaval y utopía. Sostenemos que en la tradición poética recopilada por Violeta en los campos chilenos (Cantos Folklóricos Chilenos) hay géneros, categorías e imágenes carnavalescas que son recreados por ella (Décimas) y que contienen una innegable dimensión utópica. Los aspectos ideológicos religiosos son los que mejor representan esta dimensión y en el paso de los Cantos Folklóricos Chilenos a las Décimas podemos observar la incorporación de aspectos ideológicos afines al socialismo que cuestionan radicalmente los aspectos ideológicos religiosos (discurso eclesiástico) y renuevan el carácter carnavalesco y utópico de la poesía popular recreada por Violeta Parra.
Rodrigues, Fernando Manuel Elias. "António, o Cardoso do ginásio : lugares de um ator invulgar". Master's thesis, 2018. http://hdl.handle.net/10451/36726.
Pełny tekst źródłaAntónio Cardoso (António José Ferreira Cardoso, Lisbon 1861–1917) was an important Portugese actor in a period that goes from the last two decades of the 19th century to the first years of the 20th century. He made his debut aas an amateur in 1878 at Sociedade Guilherme Cossoul in the cast of the comedy Casar por Anúncio. As a professional, he made his debut in 1881 at Teatro do Rato in the comedy Zé Povinho. In 1883 he entered the company at Teatro do Ginásio, being part of the cast of the comedy A Medalha da Virgem. Although he performed on almost every stage in Lisbon, his career took place at the Ginásio, and he was affectionately known as “Cardoso do Ginásio”. As a man of integrity, humble and unaffected, he was loved by all who knew him: colleagues, empresarios, journalists and the public in general. His plump physique, together with his bulging eyes, predisposed him to comedy. He created several characters that delighted audiences. Such types as “the father-in-law”, “the boy”, and transvestite “dames” were famous. Unhappy in love, he lived at his sister's house, where he died at 56 years of age.
Silva, Maria da Conceição dos Santos. "Quando o escritor toma partido: ficção e história em Bar Don Juan". Master's thesis, 2007. http://hdl.handle.net/10451/478.
Pełny tekst źródłaEste estudo interdisciplinar tem como objectivo estabelecer um diálogo com a obra de arte, privilegiando a relação entre História e Literatura, tendo como fonte o romance Bar Don Juan, que introduz no seu enredo narrativo representações políticas, sociais e culturais da década de 1960, período da História recente do Brasil marcado pelo ideal revolucionário da vanguarda intelectual (esquerda festiva), bem como pela repressão e a censura dos governos militares que se seguiram ao golpe de 1964. A sintonia deste romance com o momento histórico possibilita dirigir um olhar atento para o seu enredo e suas personagens, dado que a obra literária está inscrita no seu tempo histórico e traz consigo os códigos e as referências do mundo que a ficção é capaz de abarcar, mesmo sem ter o compromisso com a verdade histórica dos factos nem com a realidade que a cerca.
Correia, Anabela Barros. "O espelho deformante: imagens do grotesco em Fatal dilema, de Abel Botelho". Master's thesis, 2008. http://hdl.handle.net/10451/337.
Pełny tekst źródłaNeste estudo centra-se a atenção sobre a obra de Abel Botelho, escritor português do século XIX e dos primeiros anos do século XX. Considerado um dos maiores nomes do Naturalismo português, actualmente a sua obra foi relegada ao esquecimento. Com o objectivo de demonstrar a lacuna que representa tal esquecimento, em primeiro lugar, fez-se uma abordagem da sua obra, tendo como núcleo de reflexão o ciclo Patologia Social, série de cinco romances pelos quais o escritor se tornou mais conhecido. Considerou-se ainda relevante focar alguns aspectos da recepção da obra botelhiana, de modo a comprovar a sua relevância no seu tempo. Sendo um escritor naturalista, Abel Botelho seguiu a estética naturalista, uma poética traída nos seus preceitos pelos seus escritores, em cuja escrita irrompe o grotesco, a deformação da realidade objectiva que realistas e naturalistas tentaram captar. Abel Botelho não foi excepção e, portanto, demonstrou-se a relação entre o grotesco e a estética naturalista. Delimitou-se a análise do grotesco na obra de Abel Botelho ao quarto romance do ciclo Patologia Social, Fatal Dilema. Nessa análise salientaram-se as manifestações do grotesco, que, na escrita botelhiana, se evidencia com os seus contrastes, em imagens do sublime e da beleza. Na segunda parte da análise, verificou-se o poder do delírio e da emoção, ao deformar a representação naturalista da realidade, mediante distorções e símbolos, que criam uma visão grotesca do mundo representado e confirmam o grotesco como registo dominante na ficção botelhiana.
In this study the attention is centered upon Abel Botelho's work, Portuguese writer of the 19th century and 20th century's early years. Considered one of the greatest names of the Portuguese Naturalism, his work was nowadays relegated to obliviousness. With the purpose of demonstrate the lacuna that such obliviousness represents, on the first place, it was made a broaching of his work, having as nucleus of reflection the cycle Patologia Social (Social Pathology), series of five novels by which the writer became most known. It was still considered relevant to focus some aspects of the reception of Botelhian work, in order to prove its relevance in its time. As a naturalist writer, Abel Botelho followed the naturalist aesthetics, a poetics betrayed in its precepts by its writers, in whose writing spouts out the grotesque, the deformation of the objective reality that realists and naturalists tried to catch. Abel Botelho was not an exception and, therefore, it was demonstrated the relation between the grotesque and the naturalist aesthetics. The analysis of the grotesque in Abel Botelho's work was delimited to the fourth novel of the cycle Patologia Social (Social Pathology), Fatal Dilema (Fatal Dilemma). In that analysis were pointed out the manifestations of the grotesque, which, in the Botelhian writing, stands out with its contrasts, in images of the sublime and beauty. In the second part of the analysis, it was verified the power of delirium and emotion, when deforming the naturalist representation of reality, through distortions and symbols, which create a grotesque vision of the represented world and confirm the grotesque as a dominant register in the Botelhian fiction.
Martens, Erika. "Ideology and literature : a study of society and literary criticism with special reference to the reception of Heinrich Boll during the 1970's / Erika Martens". 1988. http://hdl.handle.net/2440/18853.
Pełny tekst źródła340 leaves ; 30 cm.
Title page, contents and abstract only. The complete thesis in print form is available from the University Library.
Thesis (Ph.D.)--University of Adelaide, 1988
Page, Rosemary Jean. "So many voices urging : transformation, paradox and continuity in the poetry of James McAuley". Doctoral thesis, 2017. http://hdl.handle.net/10451/35102.
Pełny tekst źródłaEsta dissertação aborda a obra do poeta australiano James McAuley (1917-76), conhecido pela polémica “anti modernismo” enquanto coinventor de um poeta anti surrealista, mas também pela poesia íntima e lírica usando formas modernistas e imagistas. Apesar de se tratar de uma leitura sequencial de proximidade, sublinha-se a diversidade e consistência deste importante poeta, mostrando como a fase “anti modernista” e as muitas experiências, revisões e transformações foram produzidas por um impulso antitético em busca de uma poética adequada, do conhecimento do eu e da forma de ser poeta no seu tempo. Uma análise extensiva da obra mostra como tal transformação foi gerada por ciclos de resposta e oposição ao contexto cultural, literário e artístico do tempo, numa dialética entre impulsos românticos, modernistas, avant-garde e realistas. Um padrão consistente, mas não premeditado, de transformação observa-se na utilização de vozes sucessivas que vão, na obra inicial modernista, do observador da natureza e vagabundo urbano, até ao parodista contra o surrealismo. Posteriormente, mudou para géneros e diálogos neoclássicos no lirismo comemorativo cristão, no foco seiscentista da epístola “A Letter to John Dryden” e nas personagens heroicas do épico moderno Captain Quiros. Esta postura “contra a corrente” foi abandonada, surpreendentemente, em meados da década de 1960, preferindo um tema mais contemporâneo e autobiográfico explorando a história pessoal e, na década de 1970, num aparente retorno ao lirismo neossimbolista inicial e à voz realista do observador da natureza. Esta dissertação explora constantes tópicas, simbólicas e temáticas, a insistência de McAuley na competência formal, a busca de um simbolismo baseado em imagens e questões permanentes sobre identidade e cultura, o lugar e a sua diferenciação, assim como uma estimulante procura da ordem e de um elemento metafísico em meados do século XX.
Hofer, Martin. "Hans Rietschel (1878-1970) - Direktor der Universitäts-Kinderklinik Würzburg von 1917-1946". Doctoral thesis, 2006. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-19480.
Pełny tekst źródłaHans Rietschel (1878–1970), son of Georg Rietschel, Professor of Theologie at the University of Leipzig, was born on 11 September 1878 in Wittenberg (Wittenberg county). From 1897–1902 he studied medicine at the Universities of Leipzig and Tübingen. Having passed his medical degree and thesis „Ueber verminderte Leitungsgeschwindigkeit des in ‚Ringer’scher Lösung‘ überlebenden Nerven“ in 1902 he started his career as a clinician at the Medizinischen Klinik, University of Leipzig and the Municipal Hospital St. Jakobus, Leipzig. From 1904-1907 his specialisation in Paediatrics was supervised by Otto Heubner Department of Paediatrics at the Charité in Berlin. Otto Heubner was the first „Ordinarius“ for Paediatrics in Germany. Rietschels scientific publications dating from those years deal with problems concerning the nutrition of neonates and infants. From 1907-1917 Hans Rietschel was the directing physician at an institution for ill neonates and infants in Dresden. As a reward for his work during the exhibition for Hygiene in 1911 in Dresden he was honoured with the title of a professor. In 1917 Rietschel became „Extraordinarius“ in Paediatrics at the Universitiy of Würzburg. 1921 the University changed this into a „planmäßiges Ordinariat“. In 1923 the department moved into the newly built Luitpold- hospital. Besides patient care, which was difficult during the years of World War II, Rietschel supervised a great number of scientific projects in the fields of paediatric nutrition, infectiology and the role of vitamin C and D. The „era“ Rietschel from 1917-1946 includes also the era of the „3rd Reich“. During this period the pediatricians and the children were submitted to new difficult circumstances as persecution of the Jewish paediatricians und the so called „Euthanasia“ of selected children. Regarding the documents which where accessible, it can be stated that there were three Jewish paediatricians in Rietschels department before 1933, but none after 1933. There was no proof found of any participation of Rietschel or his department in „Euthanasia“ of children. The sterilisation of children was not investigated systematically. According to the documents available, Rietschel does not appear to be convinced of the ideas of nationalsocialism or anti-Semitism or so called „eugenic ideas“ which were quite popular from the end of the 19th century onwards. From 1933-1938 Rietschel was part of the leading committee, from 1934-1936 chairman of the German society of Paediatricians (DGfK). In this position he tolerated the politics of nationalsocialism, especially the persecution of the Jews in the community of the paediatricians. In 1946, after World War II, Rietschel was dismissed from his position by the allied forces. The board of denazification classfied him as a nominal member of the fascist regime. Until 1953 he fought for his pension, finally with success. In 1958 he was honoured with the doctor of honours by the University of Dresden, 1965 with the „Rinecker Medal“ in gold by the Medical Faculty of the University of Würzburg. In 1970 Hans Rietschel died after a short period of illness in Wertheim, Bavaria
Seo, Ean Jeong. "Construction of recombinant E. coli Nissle 1917 (EcN) strains for the expression and secretion of defensins". Doctoral thesis, 2012. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-72005.
Pełny tekst źródłaThe probiotic Escherichia coli strain Nissle 1917 (EcN) is one of the few probiotics licensed as a medication in several countries. Best documented is its effectiveness in keeping patients suffering from ulcerative colitis (UC) in remission. This might be due to its ability to induce the production of human beta defensin 2 (HBD2) in a flagellin-dependent way in intestinal epithelial cells. In contrast to ulcerative colitis, for Crohn´s disease (CD) convincing evidence is lacking that EcN might be clinically effective, most likely due to the genetically based inability of sufficient defensin production in CD patients. As a first step in the development of an alternative approach for the treatment of CD patients, EcN strains were constructed which were able to produce human alpha-defensin 5 (HD5) or beta-defensin 2 (HBD2). For that purpose codon-optimized defensin genes encoding either the proform with the signal sequence or the mature form of human alpha defensin 5 (HD5) or the gene encoding HBD2 with or without the signal sequence were cloned in an expression vector plasmid under the control of the T7 promoter. Synthesis of the encoded defensins was shown by Western blots after induction of expression and lysis of the recombinant EcN strains. Recombinant mature HBD2 with an N-terminal His-tag could be purified by Ni-column chromatography and showed antimicrobial activity against E. coli, Salmonella enterica serovar Typhimurium and Listeria monocytogenes. In a second approach, that part of the HBD2-gene which encodes mature HBD2 was fused with yebF gene. The resulting fusion protein YebFMHBD2 was secreted from the encoding EcN mutant strain after induction of expression. Presence of YebFMHBD2 in the medium was not the result of leakage from the bacterial cells, as demonstrated in the spent culture supernatant by Western blots specific for ß-galactosidase and maltose-binding protein. The dialyzed and concentrated culture supernatant inhibited the growth of E. coli, Salmonella enterica serovar Typhimurium and Listeria monocytogenes in radial diffusion assays as well as in liquid coculture. This demonstrates EcN to be a suitable probiotic E. coli strain for the production of certain defensins
Troge, Anja. "Studien am Flagellensystem des Escherichia coli Stammes Nissle 1917 (EcN) im Hinblick auf seine Funktion als Probiotikum". Doctoral thesis, 2012. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-74201.
Pełny tekst źródłaEscherichia coli Nissle 1917 (EcN) is one of the best studied and characterized probiotic bacterial strains. It is in use as a drug since the beginning of last century to treat various diseases and dysfunctions of the human intestinal tract, e.g. diarrhea, inflammatory bowel diseases and obstipation. The flagellum of EcN mediates motility and is able to induce human beta defensin 2 (hBD2) production by epithelial cells. Therefore, this organelle is directly involved in EcN’s probiotic function. It has been shown that the flagella of several other bacteria, including the probiotic strain Bacillus cereus CH or the pathogenic strains Pseudomonas aeruginosa and Clostridium difficile, mediate adhesion to intestinal mucus, which is secreted by epithelial cells. However it remained unclear which part of the flagella binds to which mucus component. The ability to adhere efficiently to host tissue is considered to be an important attribute for a probiotic strain. Ex vivo adhesion studies with cryosections of human gut biopsies have revealed, that the flagellum of EcN must be involved in efficient adhesion to human intestinal tissue. Thus, the function of EcN’s flagellum as an adhesin was investigated in this work. First, the hyperflagellated variant EcN ATHF was isolated and characterized by several experiments, e.g. motility tests and electron microscopy. Further ex vivo adhesion studies with EcN ATHF demonstrated a higher adhesion efficiency of this hyperflagellated variant confirming the role of the flagellum for adhesion of EcN to cryosections of human gut biopsies. Interestingly, EcN’s flagellum did not function as an adhesin in in vitro adhesion studies with the human epithelial cells Caco-2 and T24. These differences between the in vitro and ex vivo studies led to the assumption, that in vivo the flagellum of EcN mediates adhesion to mucus, which is not produced by Caco-2 and T24 cells, but was shown to be present in the cryosections of human gut biopsies. This was confirmed by in vitro adhesion studies with the mucin-producing epithelial cell line LS174-T, as flagella were essential for efficient adhesion to these cells. Furthermore, preincubation of flagellated EcN strains with mucin2 (porcine stomach) reduced their adhesion effiency to cryosections of human gut biopsies. To demonstrate the direct interaction between flagella from EcN wildtype and mucus, an ELISA was established. A direct concentration-dependent interaction between isolated flagella from EcN wildtype and mucin2 as well as human mucus (Colon) could be observed. In contrast, there was no direct interaction between isolated flagella from EcN wildtype and murine mucus (Duodenum, Ileum, Ceacum, Colon), indicating that mucus composition varies among different species. By testing different carbohydrates - known to be constituents of mucus - for their interaction with the flagellum of EcN, gluconate was identified as one receptor. Preincubation of isolated flagella with gluconate significantly reduced their interaction with mucin2 or human mucus. Additionally, the surface exposed domain D3 of flagellin, the major subunit of the flagellum, could be excluded to be responsible for the interaction with mucin2 or human mucus. Flagella, which were isolated from a domain D3 deficient mutant, bound even more efficient to mucin2 as well as to human mucus. Furthermore the change of pH had significant effects on the interaction between mucus and isolated flagella, probably due to conformational changes. In summary, this study identified the flagellum as a novel and apparently major adhesin in vivo of the probiotic EcN by employing a hyperflagellated variant, a ΔfliC mutant as well as the corresponding complemented strain. Additionally, EcN is so far the first probiotic strain, for which it has been shown, that its flagella directly bind to human mucus. Thereby the mucus component gluconate was identified as an important receptor. As some pathogens have been reported to use their flagella for adhesion to human host tissue, this organelle might enable EcN to compete with pathogens for successful colonization of the gut, which has been postulated to be a prerequisite for probiotics
Grozdanov, Lubomir Assenov. "Analysis of the genome organization and fitness traits of non-pathogenic Escherichia coli strain Nissle 1917 (O6:K5:H1)". Doctoral thesis, 2004. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-9304.
Pełny tekst źródłaBislang wurden die kompletten Genomsequenzen von mehr als 100 Bakterien ermittelt. Mehr als ein Drittel dieser Organismen wird als pathogen eingestuft. Die Verfügbarkeit dieser Sequenzinformation vergrößert unser Wissen über die bakterielle Genomstruktur und – plastizität sowie über mikrobielle Diversität und Evolution. Diese Daten bilden die Grundlage für viele Fortschritte auf dem Gebiet der Biotechnologie, der industriellen-, Umwelt- und medizinischen Mikrobiologie: neuartige Typisierung-, Diagnostik- und Therapieansätze sowie die Entwicklung neuer Medikamente und Impfstoffe basieren auf und profitieren von der ständig zunehmenden Menge an DNA-Sequenzen. Genomanalysen sind zusammen mit anderen molekularbiologischen Methoden wie PCR, DNA-Chiptechnologie, subtraktive Hybridisierung und Proteomanalysen von zunehmender Bedeutung für die Erforschung von Infektionskrankheiten und das öffentliche Gesundheitswesen. Ziel dieser Arbeit war die Analyse der Genomstruktur und des Genominhaltes des apathogenen Escherichia coli Stammes Nissle 1917 (O6:K5:H1) und der Vergleich mit verfügbaren Daten verschiedener pathogener und apathogener E. coli Stämme sowie anderer eng-verwandter Spezies. Eine Cosmid-Genbank des Stammes Nissle 1917 wurde nach Klonen durchsucht, die für Fitnessfaktoren kodieren, welche zur erfolgreichen Kolonisierung des menschlichen Verdauungstraktes und zum probiotischen Charakter dieses Stammes beitragen. Vier genomische Inseln (GEI I-IVNissle 1917) wurden nachgewiesen und charakterisiert. Auf diesen GEIs befinden sich verschiedene bekannte Fitness-Determinanten (mch/mcm, foc, iuc, kps, ybt), bislang nicht charakterisierte ORFs, mobile genetische Elemente und bislang für den Stamm Nissle 1917 nicht beschriebene Gene, die möglicherweise zur Fitness und Adaptabilität dieses Stammes beitragen. Die GEIs I-IVNissle 1917 sind jeweils mit einem tRNAGen assoziiert und ähneln hinsichtlich ihrer Struktur und chromosomalen Lokalisation entsprechenden Inseln im Genom des uropathogenen E. coli Stammes CFT073 (O6:K2(?):H1). Interessanterweise fehlen auf diesen wichtige Virulenzgene uropathogener E. coli (hly, cnf, prf/pap). Eine etwa 30 kb große Region der GEI IINissle 1917, die von IS2 Elementen flankiert wird, kann spontan deletieren, was zum Verlust verschiedener Fitnessdeterminanten (iuc, sat, iha) führt. Darüber hinaus wurde der chromosomale Sequenzkontext von tRNA-Genen mittels PCR auf die Integration von „Fremd-DNA“ hin untersucht, die durch horizontalen Gentransfer erworben wurde (tRNA Screening), und mit denen anderer apathogener und pathogener E. coli Stämme verglichen. Der genomweite Anteil an tRNA-Gen-assoziierter, möglicherweise horizontal erworbener DNA, die im I. Summary 2 apathogenen E. coli K-12 Stamm MG1655 fehlt, unterschied sich dabei nicht bedeutend im Stamm Nissle 1917 und den uropathogenen E. coli O6 Stämmen CFT073 und 536. Die Verbreitung von DNA-Regionen der GEIs des Stammes Nissle 1917 wurde mittels PCR bei apathogenen E. coli-Isolaten sowie bei uropathogenen E. coli O6:K5-Isolaten untersucht. Nur zwei UPEC O6:K5-Isolate enthielten alle GEI-Bereiche, die in diese Untersuchung einbezogen waren, unterschieden sich jedoch vom Stamm Nissle 1917 durch ihre Phänotypen. Die Makrorestriktionsanalyse der Genomstruktur des E. coli Stammes Nissle 1917 zeigte, daß letztere der des uropathogenen E. coli Stammes CFT073 sehr ähnelt. Um die Ursache für den semi-rauhen Phänotyp des Stammes Nissle 1917 zu untersuchen, wurden die wa* und wb* Determinanten dieses Stammes, die für die LPS-Biosynthese verantwortlich sind, kloniert und sequenziert. Das bislang unbekannte Serotyp O6-spezifische O-Antigenpolymerase-kodierende Gen wzy des Stammes Nissle 1917 wurde charakterisiert und mit dem des rauhen O6 Stammes 536 verglichen. Eine Punktmutation, die zu einem vorzeitigen Translationsstop der wzy-Transkripte des Stammes Nissle 1917 führt, wurde als Ursache für den semi-rauhen Phänotyp und damit auch die Serumsensitivität dieses Stammes verantwortlich gemacht. Zur Untersuchung der Kolonisierungsfähigkeit des E. coli Stammes Nissle 1917 wurden verschiedene Faktoren, die an der Biofilmbildung bzw. am multizellulären Verhalten beteiligt sind, sequenziert und näher analysiert. Die Seqenzierung der fim Determinante zeigte, daß das fimB Gen, das für die Expression der Typ 1-Fimbrien benötigt wird, durch die Insertion eines IS-Elementes inaktiviert wurde. Untersuchungen zum multizellulären Verhalten zeigten, daß der Stamm Nissle 1917 den sogenannten „rdar“ Morphotyp, hervorgerufen durch Expression von Curli-Fimbrien und Cellulose, bei 30 °C und bei 37 °C exprimiert, nicht jedoch die uropathogenen E. coli Stämme 536 und CFT073. Das Cellulosebiosynthese-Operon (bcs) sowie das Gen rfaH, das für einen Transkriptionsantiterminator kodiert, wurden im Stamm Nissle 1917 inaktiviert, um deren Bedeutung für den „rdar“ Morphotyp zu untersuchen. Während Cellulose für die Expression des „rdar“ Morphotyps benötigt wird, hatte die rfaHInaktivierung keinen Einfluß auf dieses mulizelluläre Verhalten des E. coli Stammes Nissle 1917. Die Ergebnisse dieser Arbeit zeigen, daß der apathogene E. coli Stamm Nissle 1917 durch eine spezifische Kombination phänotypischen Eigenschaften gekennzeichnet ist, die ihn von anderen bislang untersuchten E. coli Stämmen unterscheidet. An der Evolution dieses Stammes, möglicherweise aus einem pathogenen „Vorfahren“, waren vielfältige Gentransfer- und Deletionsprozesse sowie Punktmutationen beteiligt
Bury, Susanne. "Molekularbiologische Untersuchungen der antagonistischen Effekte des probiotischen \(Escherichia\) \(coli\) Stamms Nissle 1917 auf Shiga-Toxin produzierende \(Escherichia\) \(coli\) Stämme". Doctoral thesis, 2018. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-163401.
Pełny tekst źródłaShiga toxin producing E. coli strains (STEC) are a great concern to human health. Upon an infection with as few as 100 bacteria, humans can develop disease symptoms ranging from watery to bloody diarrhea or even develop the hemolytic uremic syndrome (HUS). The major factor contributing to the disease symptoms is Shiga toxin (Stx) which can bind to the eukaryotic cells in the intestine of the human and induce cell death via apoptosis. Based, among other things, on the microbiota composition, the impact of STEC can vary. Some bacteria of the microbiota can interfere with the colonization of STEC strains in the first place. Others cannot impair the colonization but interfere with the toxin production and there are still others which are even infected by stx encoding phages, being released from STEC strains. Those previously harmless bacteria subsequently contribute to the toxin increase and worsen the disease progression. Since the genetic information of Stx is encoded on a prophage, antibiotic treatment of patients can lead to an increased toxin and stx-phage release and is therefore not recommended. Several STEC epidemics in different countries, which even resulted in the death of some patients, demonstrated that there is an urgent need for alternative treatment strategies. The E. coli strain Nissle 1917 (EcN) has been used as a probiotic to treat gastrointestinal infections for more than 100 years. It harbors several fitness factors which contribute to the establishment of an intact intestinal barrier in the human gut. Moreover, studies with EcN unraveled that the probiotic E. coli can interfere with the colonization of STEC strains and their toxin production. This study aimed to investigate if EcN could be a possible alternative or supplementary treatment strategy for STEC infected patients, or a preventive treatment for the patient’s close contact persons. Therefore, EcN was firstly investigated for a possible stx-prophage integration into its’s genome which would eliminate it from being a potential treatment due to the possibility of disease worsening. Despite the presence of the stx-phage surface receptor YaeT, EcN demonstrated a complete resistance towards the lysis and the lysogeny by stx-phages, which was proven by PCR, phage-plaque assays and phage enrichment approaches. Transcriptome data could unravel that a lambdoid prophage in the genome of EcN is involved in the resistance towards the phage infection. Other commensal E. coli tested presented a stx-phage resistance as well and in silico analysis revealed that all of them harbor a complete lambdoid prophage besides the stx-phage susceptible K-12 strain MG1655. We assume that the resistance of EcN towards a stx-phage infection is connected to the presence of an intact lambdoid prophage which interferes with superinfection. Further experiments regarding the impact of the microcin negative EcN mutant SK22D towards STEC strains depicted that SK22D did not only interfere with the toxin production but also negatively regulated the transcription of the entire stx-prophage in coculture with all STEC strains tested (O157:H7, O26:H11, O145:H25, O103:H2, O111:H- and two O104:H4 isolates from the 2011 outbreak in Germany). This influence on the pathogenic factor production was evinced to be cell contact independent as SK22D could even interfere with the pathogenic factor production when being separated from the STEC strain EDL933 by a Transwell membrane with the pore size of 0.4 µm. From this data we concluded, that factor(s) released by SK22D interfere with the lysis of STEC strains by stabilizing the lysogenic state. Another positive aspect of EcN towards the pathogenicity of STEC strains was encountered when EcN was incubated with isolated stx-phages. The probiotic strain could reduce the infectivity of the phages towards a MG1655 lysis from ~ 1e7 pfus/ml to 0 after 44 h of incubation. Various approaches to determine the characteristics of the factor(s) of EcN which are involved in the phage inactivation depicted it to be a heat resistant stationary phase protein on the surface of EcN, which could be a component of its biofilm. Regarding the protective role of EcN we could further evince that SK22D was capable of interfering with the lysogenic K 12 mediated increase of Stx and stx phages. Lysogenic K-12 strains were characterized by a huge increase of Stx and stx-phage production. The presence of SK22D anyhow, could interfere with this K-12 mediated pathogenic factor increase. Transwell and stx phage infection kinetics led to the proposal that SK22D interfered with the stx-phage infection of K-12 strains in the first place rather than disturbing the lysis of lysogenic K 12. The protection from the phage infection could be due to the growth of K 12 strains within the SK22D culture, whereby the phage susceptible strains are masked from phage detection. Summarizing, this work could underline the beneficial attributes of EcN towards the STEC pathogenicity in vitro. These results should be considered as pioneers for future in vivo studies to enable EcN medication as a supportive STEC infection treatment strategy
Rund, Stefan A. "Interferenz des probiotischen Escherichia coli Stammes Nissle 1917 mit Adhäsion, Replikation und Shiga Toxin Produktion von EHEC Stämmen in vitro". Doctoral thesis, 2014. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-104837.
Pełny tekst źródłaDue to extensive studies in the last decades and its centennial application as a pharmaceutical, E. coli Nissle 1917 (EcN) is among the best characterized probiotics. EcN is used as remedy for remission maintenance of ulcerative colitis, chronic obstipation and diarrhea in children. The enteroaggregative – haemorrhagic - E. coli (EAHEC) strain O104:H4 was responisible for one of the biggest outbreaks of EHEC recorded so far, that took place in Germany in 2011. Currently, there is no effective prophylaxis or treatment available for EHEC infections in humans. Therefore, alternative therapeutics are desperately needed. The antagonistic effects of EcN on pathogenic E. coli strains like the EHEC O157:H7 strain EDL933 or clinical isolates of EAHEC O104:H4 were investigated in this study. The influence of EcN on adhesion to human epithelial cell lines, the growth and the Shiga toxin production of pathogenic strains were analysed. Furthermore, the resistence of EcN against Shiga toxin phages was proven. Initially, the adhesion efficiency of EcN and pathogenic E. coli strains were determined in monocultures. EcN showed the lowest number of adhering bacteria to Caco-2 and LS-174T cells. This was insofar surprising, since probiotics are expected to adhere more efficiently to epithelial cells than pathogens. Regardless of this fact, it could be shown that EcN is inhibiting the adhesion of two EAHEC O104:H4 isolates, the closely related EAEC strain 55989 and the EHEC O157:H7 strain EDL933 to both cell lines. The microzins M and H47, which are produced by EcN, can be held responsible for a fraction of the observed anti-adhesive effect of EcN. The Microzins were also identified as the only substance that was influencing the growth of the pathogenic E. coli strains. One of the most important virulence factors of EHEC and EAHEC strains is Shiga toxin. In this study could be shown, that EcN is inhibiting the Shiga toxin production of the most common EHEC strains (big five: O157:H7, O26:H11, O103:H2, O111:H-, O145:H25) and two clinical isolates of EAHEC O104:H4 in the cell culture medium DMEM. Interesingly, the Shiga toxin 1 production of EHEC O103:H2 and O111:H- was not only reduced by EcN, but also the E. coli K-12 strain MG1655. In contrast, the Stx2 production of the serotypes O104:H4, O26:H11, O145:H25 was only blocked by EcN. The reduction of the Shiga toxin production in EAHEC O104:H4 TY3730 und TY3456, as well as EHEC O26:H11 was partly dependent on the microcin production of EcN. No influence of microzins on the Stx production of EHEC O157:H7 EDL933 and EHEC O145:H25 was detected. When using LB-medium instead of DMEM-medium, no influence of microzin on the Shiga toxin production of neither EAHEC TY3730 and TY3456, nor EHEC EDL933 could be shown. Experiments with SCEM-medium also resulted in an EcN-dose-dependent inhibition of Shiga toxin production of pathogenic E. coli strains in co-culture with EcN. In order to investigate the mechanism responsible for the observed effects, the EcN mutant EcN::luxS was used in co-culture experiments. However, the deletion of the quorum sensing molecule AI-2 in EcN::luxS had no influence on the Stx production. Using acetate in the experiments did not, in contrast to published results, lead to a reduction of Shiga toxin production. In addition, an influence of EcN on lysis of EHEC strains or the secretion of Shiga toxin could be ruled out. To study the Shiga toxin expression an assay with a bioluminescent C-P (chromosome-plasmid) reporter system was successfully established. Here, Shiga toxin expression could be monitored in real time with the strain background EHEC EDL933. Moreover, a reduction of Shiga toxin expression in co-culture with EcN could be detected. In further experiments could be shown, that EcN is not only reducing the Shiga toxin production in uninduced bacteria, but also in the Mitomycin C induced EAHEC O104:H4 strain TY3730. An important safety issue, in order to use EcN as a pharmaceutical against EHEC strains, is the resistance of EcN against Shiga toxin phages. The infection of bacteria was here investigated with phage plaque assay, stx-PCR, Stx-ELISA and K+-efflux assay. With these different methods could be successfully shown, that EcN is not infected by the tested Shiga toxin phages. A mutation in the phage receptor LamB could be a possible, but still unconfirmed, phage resistance mechanism of EcN. In summary, this study showed important antagonistic effects of EcN against pathogenic E. coli strains, which could be the foundation of new and desperately needed treatment options of EHEC infections
Freire, Sofia Vieira Martins de Matos. "De Angola à contracosta e Baía dos Tigres: da vertigem do espaço imperial ao conhecimento do outro". Master's thesis, 2013. http://hdl.handle.net/10451/8816.
Pełny tekst źródłaEsta dissertação explora a comparação entre narrativas de viagem que relatam o mesmo percurso, porém com objectivos diferentes: De Angola à Contracosta, de Hermenegildo Capelo e Roberto Ivens (cuja expedição foi realizada em 1884) e de Baía dos Tigres, de Pedro Rosa Mendes (que atravessou igualmente o continente africano, de Angola a Moçambique, em 1997). A diferença que ressalta da vertigem de um século que distancia as duas obras assenta principalmente no olhar dos viajantes sobre o Outro e sobre diferentes perspectivas de construção da alteridade. Esta comparação permite apresentar uma proposta incontornável, sobretudo tendo em conta o processo de globalização em que vivemos: a construção de um diálogo intercultural efectivo, visando a superação de uma ideologia colonial e etnocêntrica que, apoiada pelas certezas científicas da época (século XIX), alicerçou os fundamentos que estão na base da hierarquização da diferença e, por conseguinte, do racismo
ABSTRACT: This thesis explores the comparison between travel narratives that refer to the same route, but with different goals: De Angola à Contracosta of Hermenegildo Capelo and Roberto Ivens, whose expedition took place in 1884; and Baía dos Tigres, of Pedro Rosa Mendes, who also crossed the African continent, from Angola to Mozambique, in 1997. The difference that is highlighted by a century of vertigo which distances the two works is based mainly in the regard of these travelers over the Other and about different ways of constructing otherness. This comparison allows us to present a compelling proposition, particularly given the globalization process we live in today: building an effective intercultural dialogue in order to overcome a colonial and ethnocentric ideology that, supported by the scientific certainty of the time (XIX century), has founded the fundamentals that underlie the hierarchy of difference and therefore racism.
Gonçalves, Diogo Pereira da Silva 1990. "A espacialidade na escultura do séc. XX : do espaço fechado ao espaço negativo". Master's thesis, 2018. http://hdl.handle.net/10451/33691.
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