Articoli di riviste sul tema "XIAP inhibitors"
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Löder, Sandra, Melanie Fakler, Irmela Jeremias, Klaus-Michael Debatin e Simone Fulda. "XIAP Inhibitors Present a Promising New Strategy to Sensitize Childhood Acute Leukemia Cells for Chemotherapy-Induced Apoptosis." Blood 114, n. 22 (20 novembre 2009): 3791. http://dx.doi.org/10.1182/blood.v114.22.3791.3791.
Testo completoLoeder, Sandra, Thorsten Zenz, Andrea Schnaiter, Daniel Mertens, Dirk Winkler, Hartmut Döhner, Klaus-Michael Debatin, Stephan Stilgenbauer e Simone Fulda. "A Novel Paradigm to Trigger Apoptosis in Chronic Lymphocytic Leukemia." Blood 114, n. 22 (20 novembre 2009): 731. http://dx.doi.org/10.1182/blood.v114.22.731.731.
Testo completoFakler, Melanie, Sandra Löder, Meike Vogler, Katja Schneider, Irmela Jeremias, Klaus-Michael Debatin e Simone Fulda. "Small Molecule XIAP Inhibitors Cooperate with TRAIL to Trigger Apoptosis in Childhood Acute Leukemia Cells and Overcome Bcl-2-Mediated Resistance". Blood 112, n. 11 (16 novembre 2008): 857. http://dx.doi.org/10.1182/blood.v112.11.857.857.
Testo completoSchimmer, Aaron D., Marcela Gronda, Zhiliang Wang, Kate Welsh, Clemencia Pinilla, Michael Andreeff, Wendy D. Schober et al. "Small-Molecule XIAP Inhibitors Derepress Downstream Effector Caspases and Induce Apoptosis of Leukemia Cell Lines and Patient Samples." Blood 104, n. 11 (16 novembre 2004): 759. http://dx.doi.org/10.1182/blood.v104.11.759.759.
Testo completoSchimmer, Aaron D., e Shadi Dalili. "Targeting the IAP Family of Caspase Inhibitors as an Emerging Therapeutic Strategy". Hematology 2005, n. 1 (1 gennaio 2005): 215–19. http://dx.doi.org/10.1182/asheducation-2005.1.215.
Testo completoSchimmer, Aaron D., e Shadi Dalili. "Targeting the IAP Family of Caspase Inhibitors as an Emerging Therapeutic Strategy". Hematology 2005, n. 1 (1 gennaio 2005): 215–19. http://dx.doi.org/10.1182/asheducation.v2005.1.215.215.
Testo completoFakler, Melanie, Sandra Loeder, Meike Vogler, Katja Schneider, Irmela Jeremias, Klaus-Michael Debatin e Simone Fulda. "Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2–mediated resistance". Blood 113, n. 8 (19 febbraio 2009): 1710–22. http://dx.doi.org/10.1182/blood-2007-09-114314.
Testo completoSeno, Saki, Minori Kimura, Yuki Yashiro, Ryutaro Kimura, Kanae Adachi, Aoi Terabayashi, Mio Takahashi et al. "β-Thujaplicin Enhances TRAIL-Induced Apoptosis via the Dual Effects of XIAP Inhibition and Degradation in NCI-H460 Human Lung Cancer Cells". Medicines 8, n. 6 (2 giugno 2021): 26. http://dx.doi.org/10.3390/medicines8060026.
Testo completoCillessen, Saskia A. G. M., John C. Reed, Kate Welsh, Clemencia Pinilla, Richard Houghten, Erik Hooijberg, José Deurhof et al. "Small-molecule XIAP antagonist restores caspase-9–mediated apoptosis in XIAP-positive diffuse large B-cell lymphoma cells". Blood 111, n. 1 (1 gennaio 2008): 369–75. http://dx.doi.org/10.1182/blood-2007-04-085480.
Testo completoGaponova, Tatyana, Andrey Misurin, Larisa Mendeleeva, Elena Varlamova, Elena Parovichnikova e Valeryi Savchenko. "Expression of XIAP in Multiple Myeloma Patients". Blood 112, n. 11 (16 novembre 2008): 5118. http://dx.doi.org/10.1182/blood.v112.11.5118.5118.
Testo completoPolykretis, Panagis, Enrico Luchinat, Alessio Bonucci, Andrea Giachetti, Melissa A. Graewert, Dmitri I. Svergun e Lucia Banci. "Conformational characterization of full-length X-chromosome-linked inhibitor of apoptosis protein (XIAP) through an integrated approach". IUCrJ 6, n. 5 (23 agosto 2019): 948–57. http://dx.doi.org/10.1107/s205225251901073x.
Testo completoDing, Dongshen, Liang Hong e Chang Shu. "MicroRNA-5100 Modulates Lung Cancer Cell Proliferation and Apoptosis via Inhibiting X-Linked Inhibitor of Apoptosis Protein (XIAP) Expression". Journal of Biomaterials and Tissue Engineering 11, n. 10 (1 ottobre 2021): 2037–43. http://dx.doi.org/10.1166/jbt.2021.2790.
Testo completoFarag, Marc, Charline Kieffer, Nicolas Guedeney, Anne Sophie Voisin-Chiret e Jana Sopkova-de Oliveira Santos. "Computational Tool to Design Small Synthetic Inhibitors Selective for XIAP-BIR3 Domain". Molecules 28, n. 13 (30 giugno 2023): 5155. http://dx.doi.org/10.3390/molecules28135155.
Testo completoZou, Tongtong, Jaladanki N. Rao, Xin Guo, Lan Liu, Huifang M. Zhang, Eric D. Strauch, Barbara L. Bass e Jian-Ying Wang. "NF-κB-mediated IAP expression induces resistance of intestinal epithelial cells to apoptosis after polyamine depletion". American Journal of Physiology-Cell Physiology 286, n. 5 (maggio 2004): C1009—C1018. http://dx.doi.org/10.1152/ajpcell.00480.2003.
Testo completoCarter, Bing Z., Marcela Gronda, Zhiliang Wang, Kate Welsh, Clemencia Pinilla, Michael Andreeff, Wendy D. Schober et al. "Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells". Blood 105, n. 10 (15 maggio 2005): 4043–50. http://dx.doi.org/10.1182/blood-2004-08-3168.
Testo completoKater, Arnon P., Frank Dicker, Massimo Mangiola, Kate Welsh, John Ostresh, Richard Houghten, John C. Reed, Thomas J. Kipps e Clemencia Pinilla. "Inhibition of XIAP Renders Newly CD40-Activated Chronic Lymphocytic Leukemia Cells Sensitive to Fas (CD95) Mediated Apoptosis." Blood 104, n. 11 (16 novembre 2004): 3474. http://dx.doi.org/10.1182/blood.v104.11.3474.3474.
Testo completoLeverkus, Martin, Martin R. Sprick, Tina Wachter, Thilo Mengling, Bernd Baumann, Edgar Serfling, Eva-B. Bröcker, Matthias Goebeler, Manfred Neumann e Henning Walczak. "Proteasome Inhibition Results in TRAIL Sensitization of Primary Keratinocytes by Removing the Resistance-Mediating Block of Effector Caspase Maturation". Molecular and Cellular Biology 23, n. 3 (1 febbraio 2003): 777–90. http://dx.doi.org/10.1128/mcb.23.3.777-790.2003.
Testo completoPark, Cheol-Min, Chaohong Sun, Edward T. Olejniczak, Alan E. Wilson, Robert P. Meadows, Stephen F. Betz, Steven W. Elmore e Stephen W. Fesik. "Non-peptidic small molecule inhibitors of XIAP". Bioorganic & Medicinal Chemistry Letters 15, n. 3 (febbraio 2005): 771–75. http://dx.doi.org/10.1016/j.bmcl.2004.11.010.
Testo completoHatton, Olivia, Stacie Lambert, Sheri Krams e Olivia Martinez. "Syk survival signals in Epstein-Barr virus + B cell lymphomas (165.27)". Journal of Immunology 186, n. 1_Supplement (1 aprile 2011): 165.27. http://dx.doi.org/10.4049/jimmunol.186.supp.165.27.
Testo completoPrager, Gerald W., Judit Mihaly, Patrick M. Brunner, Yuri Koshelnick, Gunilla Hoyer-Hansen e Bernd R. Binder. "Urokinase mediates endothelial cell survival via induction of the X-linked inhibitor of apoptosis protein". Blood 113, n. 6 (5 febbraio 2009): 1383–90. http://dx.doi.org/10.1182/blood-2008-06-164210.
Testo completoHaug, Jessica, Vijay G. Ramakrishnan, Teresa Kimlinger, Timothy Halling, Linda Wellik, S. Vincent Rajkumar e Shaji Kumar. "Significant In Vitro Activity of a Novel Inhibitor of Apoptosis (IAP) Inhibitor LC161 In Multiple Myeloma". Blood 116, n. 21 (19 novembre 2010): 2998. http://dx.doi.org/10.1182/blood.v116.21.2998.2998.
Testo completoCillessen, Saskia A. G. M., John C. Reed, Clemencia Pinilla, Chris J. L. M. Meijer, Erik Hooijberg, Corine J. Hess, Kitty C. M. Castricum, Pim Kortman, Gert J. Ossenkoppele e Joost J. Oudejans. "Small-Molecule XIAP Antagonist Restores Caspase-9-Mediated Apoptosis in XIAP-Positive Diffuse Large B-Cell Lymphoma Cells." Blood 110, n. 11 (16 novembre 2007): 803. http://dx.doi.org/10.1182/blood.v110.11.803.803.
Testo completoDenault, Jean-Bernard, Brendan P. Eckelman, Hwain Shin, Cristina Pop e Guy S. Salvesen. "Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)–mediated inhibition of caspase 9". Biochemical Journal 405, n. 1 (13 giugno 2007): 11–19. http://dx.doi.org/10.1042/bj20070288.
Testo completoMohapatra, Subhra, Baoky Chu, Xiuhua Zhao, Jianguo Tao, Eduardo Sotomayor e W. Jack Pledger. "Combined Inhibition of CDK and PI3K/Akt Pathways Induces Apoptosis of Mantle Cell Lymphoma." Blood 110, n. 11 (16 novembre 2007): 1384. http://dx.doi.org/10.1182/blood.v110.11.1384.1384.
Testo completoHo, Andrew T., Qin H. Li, Hitoshi Okada, Tak W. Mak e Eldad Zacksenhaus. "XIAP Activity Dictates Apaf-1 Dependency for Caspase 9 Activation". Molecular and Cellular Biology 27, n. 16 (11 giugno 2007): 5673–85. http://dx.doi.org/10.1128/mcb.00188-07.
Testo completoLucas, H., P. M. Bartold, A. A. S. S. K. Dharmapatni, C. A. Holding e D. R. Haynes. "Inhibition of Apoptosis in Periodontitis". Journal of Dental Research 89, n. 1 (30 novembre 2009): 29–33. http://dx.doi.org/10.1177/0022034509350708.
Testo completoHe, Yanjuan, Joan Cain, Lee Ratner e Leon Bernal-Mizrachi. "Targeting xIAP Is More Important Than Bcl-Xl in Lymphomas with Constitutive Activation of NF-kB." Blood 108, n. 11 (1 novembre 2006): 2390. http://dx.doi.org/10.1182/blood.v108.11.2390.2390.
Testo completoSeca, Hugo, Liliana Santos, Joana Figueiredo, Raquel T. Lima, Jose E. Guimaraes, Clara Sambade e M. Helena Vasconcelos. "Targeting XIAP for Chemosensitization Purposes: Different Effect with Different Cytotoxic Drugs." Blood 112, n. 11 (16 novembre 2008): 1597. http://dx.doi.org/10.1182/blood.v112.11.1597.1597.
Testo completoKater, Arnon P., Frank Dicker, Massimo Mangiola, Kate Welsh, Richard Houghten, John Ostresh, Adel Nefzi, John C. Reed, Clemencia Pinilla e Thomas J. Kipps. "Inhibitors of XIAP sensitize CD40-activated chronic lymphocytic leukemia cells to CD95-mediated apoptosis". Blood 106, n. 5 (1 settembre 2005): 1742–48. http://dx.doi.org/10.1182/blood-2005-02-0695.
Testo completoLethier, Mathilde, Karine Huard, Michael Hons, Adrien Favier, Bernhard Brutscher, Elisabetta Boeri Erba, Derek W. Abbott, Stephen Cusack e Erika Pellegrini. "Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface". Life Science Alliance 6, n. 11 (6 settembre 2023): e202201784. http://dx.doi.org/10.26508/lsa.202201784.
Testo completoCarter, Bing Z., Tae Kon Kim, Duncan H. Mak, Wei Hu, Clemencia Pinilla, John C. Reed e Michael Andreeff. "AML Progenitor/Stem Cells Overexpress XIAP and Are Sensitive to the Small Molecular XIAP Inhibitor 1396-11." Blood 108, n. 11 (16 novembre 2006): 2586. http://dx.doi.org/10.1182/blood.v108.11.2586.2586.
Testo completoCarter, Bing Z., Steven M. Kornblau, Twee Tsao, Rui-Yu Wang, Wendy D. Schober, Michele Milella, Hsi-Guang Sung, John C. Reed e Michael Andreeff. "Caspase-independent cell death in AML: caspase inhibition in vitro with pan-caspase inhibitors or in vivo by XIAP or Survivin does not affect cell survival or prognosis". Blood 102, n. 12 (1 dicembre 2003): 4179–86. http://dx.doi.org/10.1182/blood-2003-03-0960.
Testo completoRunckel, Kyle L., Cory Mavis, Joseph Skitzki, Juan J. Gu, Francisco J. Hernandez-Ilizaliturri e Myron S. Czuczman. "Targeting the X-Linked Inhibitor of Apoptosis Protein (XIAP) Can Promote Tumor Cell Death, and Increase the Cytotoxic Effects of Chemotherapy Agents in in Vitro and In Vivo Models of Rituximab-Resistant Lymphoma". Blood 126, n. 23 (3 dicembre 2015): 590. http://dx.doi.org/10.1182/blood.v126.23.590.590.
Testo completoRajapakse, Hemaka. "Small Molecule Inhibitors of the XIAP Protein-Protein Interaction". Current Topics in Medicinal Chemistry 7, n. 10 (1 maggio 2007): 966–71. http://dx.doi.org/10.2174/156802607780906816.
Testo completoAbbas, Ruqaia, e Sarit Larisch. "Targeting XIAP for Promoting Cancer Cell Death—The Story of ARTS and SMAC". Cells 9, n. 3 (9 marzo 2020): 663. http://dx.doi.org/10.3390/cells9030663.
Testo completoKhan, Sumera, Kyle Runckel, Cory Mavis, Matthew J. Barth e Francisco J. Hernandez-Ilizaliturri. "Targeting XIAP Via Degradation of MDM-2 By MX69 in Aggressive Lymphomas". Blood 132, Supplement 1 (29 novembre 2018): 5379. http://dx.doi.org/10.1182/blood-2018-99-118480.
Testo completoToubai, Tomomi, Corinne Rossi, Katherine Oravecz-Wilson, Cynthia Zajac, Hideaki Fujiwawa, Stuart Brabbs, Julia Wu, Yaping Sun, John M. Magenau e Pavan R. Reddy. "IAPs Protect Host Target Tissues from Graft-Versus-Host Disease (GVHD)". Blood 128, n. 22 (2 dicembre 2016): 810. http://dx.doi.org/10.1182/blood.v128.22.810.810.
Testo completoRYAN, Ciara A., Henning R. STENNICKE, Victor E. NAVA, Jennifer B. BURCH, J. Marie HARDWICK e Guy S. SALVESEN. "Inhibitor specificity of recombinant and endogenous caspase-9". Biochemical Journal 366, n. 2 (1 settembre 2002): 595–601. http://dx.doi.org/10.1042/bj20020863.
Testo completoAkbar, Rozmeen, Mati Ur Rehman, Asra Khan, Numair Belgaumi, Iman M. Farooqui, Aafia S. Arain, Azhar Hussain Rajabali e Kulsoom Ghias. "Abstract 2549: Targeting PI3Kinase AKT pathway and anti-apoptotic protein XIAP in chemotherapy-resistant colorectal cancer cells". Cancer Research 83, n. 7_Supplement (4 aprile 2023): 2549. http://dx.doi.org/10.1158/1538-7445.am2023-2549.
Testo completoKater, Arnon P., Roman Rieger, Kate Welsh, Adel Nefzi, Richard Houghten, John C. Reed, Clemencia Pinilla e Thomas J. Kipps. "Inhibition of XIAP Enhances Specific Cytotoxic T Lymphocyte (CTL) Killing and CD20-Directed Antibody-Dependent Cellular Cytotoxicity of Chronic Lymphocytic Leukemia B Cells." Blood 104, n. 11 (16 novembre 2004): 3475. http://dx.doi.org/10.1182/blood.v104.11.3475.3475.
Testo completoCho, Seung-Ju, Young-Jong Kim, Young-Joon Surh, B. Moon Kim e Seung-Ki Lee. "Ibulocydine Is a Novel Prodrug Cdk Inhibitor That Effectively Induces Apoptosis in Hepatocellular Carcinoma Cells". Journal of Biological Chemistry 286, n. 22 (8 aprile 2011): 19662–71. http://dx.doi.org/10.1074/jbc.m110.209551.
Testo completoEyrisch, Susanne, Jose L. Medina-Franco e Volkhard Helms. "Transient pockets on XIAP-BIR2: toward the characterization of putative binding sites of small-molecule XIAP inhibitors". Journal of Molecular Modeling 18, n. 5 (30 agosto 2011): 2031–42. http://dx.doi.org/10.1007/s00894-011-1217-y.
Testo completoVan Themsche, Céline, Isabelle Mathieu, Sophie Parent e Eric Asselin. "Transforming Growth Factor-β3 Increases the Invasiveness of Endometrial Carcinoma Cells through Phosphatidylinositol 3-Kinase-dependent Up-regulation of X-linked Inhibitor of Apoptosis and Protein Kinase C-dependent Induction of Matrix Metalloproteinase-9". Journal of Biological Chemistry 282, n. 7 (6 dicembre 2006): 4794–802. http://dx.doi.org/10.1074/jbc.m608497200.
Testo completoGu, Juan J., Samuel J. Thompson, Cory Mavis, Matthew J. Barth, Pallawi Torka e Francisco J. Hernandez-Ilizaliturri. "Targeting MDM2 and XIAP By Idasanutlin in Diffuse Large B-Cell Lymphoma". Blood 134, Supplement_1 (13 novembre 2019): 5301. http://dx.doi.org/10.1182/blood-2019-129009.
Testo completoHuerta-Yepez, Sara, Mario Vega, Dorina Gui, Jonathan Said e Benjamin Bonavida. "Analysis of YY1 and XIAP Expression, Proteins That Regulate Resistance, in AIDS-NHL Tissue Arrays." Blood 106, n. 11 (16 novembre 2005): 1933. http://dx.doi.org/10.1182/blood.v106.11.1933.1933.
Testo completoKawakami, Atsushi, Tomoki Nakashima, Hideaki Sakai, Satoshi Urayama, Satoshi Yamasaki, Ayumi Hida, Masahiko Tsuboi et al. "Inhibition of Caspase Cascade by HTLV-I Tax Through Induction of NF-κB Nuclear Translocation". Blood 94, n. 11 (1 dicembre 1999): 3847–54. http://dx.doi.org/10.1182/blood.v94.11.3847.
Testo completoKawakami, Atsushi, Tomoki Nakashima, Hideaki Sakai, Satoshi Urayama, Satoshi Yamasaki, Ayumi Hida, Masahiko Tsuboi et al. "Inhibition of Caspase Cascade by HTLV-I Tax Through Induction of NF-κB Nuclear Translocation". Blood 94, n. 11 (1 dicembre 1999): 3847–54. http://dx.doi.org/10.1182/blood.v94.11.3847.423a24_3847_3854.
Testo completoKitada, Shinichi, Juan M. Zapata, Michael Andreeff e John C. Reed. "Protein kinase inhibitors flavopiridol and 7-hydroxy-staurosporine down-regulate antiapoptosis proteins in B-cell chronic lymphocytic leukemia". Blood 96, n. 2 (15 luglio 2000): 393–97. http://dx.doi.org/10.1182/blood.v96.2.393.
Testo completoKitada, Shinichi, Juan M. Zapata, Michael Andreeff e John C. Reed. "Protein kinase inhibitors flavopiridol and 7-hydroxy-staurosporine down-regulate antiapoptosis proteins in B-cell chronic lymphocytic leukemia". Blood 96, n. 2 (15 luglio 2000): 393–97. http://dx.doi.org/10.1182/blood.v96.2.393.014k47_393_397.
Testo completoTodorovic, Lidija, Gorana Stamenkovic, Biljana Vucetic-Tadic, Kazuo Umezawa, Ana Bozovic, Shunichi Yamashita e Boban Stanojevic. "Synergistic effect of 17-allylamino-17-demethoxygeldanamycin with dehydroxymethylepoxyquinomicin on the human anaplastic thyroid carcinoma cell line KTC2". Archives of Biological Sciences, n. 00 (2020): 55. http://dx.doi.org/10.2298/abs201010055t.
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