Articoli di riviste sul tema "Wm 430.5.m3"

AbstractThe metal-rich intermetallic compounds NblrSi, NblrGe, and TalrSi were synthesized by arc-melting of the elements and subsequent annealing in glassy carbon crucibles in a high-frequency furnace. The three compounds were investigated by X-ray diffraction on powders and single crystals: TiNiSi type, Pnma, a = 641.27(3), b = 379.48(2), c = 727.70(3) pm, wR2 = 0.0773, 430 F2 values for NblrSi, a = 645.48(3), b = 389.21(2), c = 741.11(4) pm, wR2 = 0.0981, 297 F2 values for NblrGe, and a = 638.11(3), b = 378.69(2), c = 726.78(3) pm, wR2 = 0.0887, 290 F2 values for TalrSi with 20 variables for each refinement. The iridium and silicon (germanium) atoms form a three-dimensional network of puckered Ir3Si3 and Ir3Ge3 hexagons in which the niobium (tantalum) atoms fill larger cages. Magnetic susceptibility measurements on NblrSi and TalrSi indicate Pauli paramagnetism with room temperature susceptibilities of 0.30(5)·10-9 and 0.97(5)·10-9 m3/mol, respectively.

In this study, new foam concretes incorporating hemp shives without the use of autoclaving have been developed and studied. Several protocols and parameters were investigated. Firstly, the influence of the addition of pozzolanic additives on the resulting density, mechanical behaviour and thermal conductivity was examined. Secondly, the effects of the incorporation of hemp shives at 5, 10 and 15 vol% on the previous three properties in such concretes were investigated. Moreover, economic cost and CO2 emissions were estimated to outline an optimized formulation of non-autoclaved biobased foam concretes. First, the target characteristics in terms of compressive strength (minimum of 2 MPa), thermal conductivity (less than 0.2 Wm−1K−1) and density (800 kg/m3) were achieved. It was noted that pozzolanic additions slightly improved the mechanical and thermal strength of non-autoclaved foamed concrete, while the addition of hemp shives improved the thermal strength but had an unfavourable effect on the mechanical strength. Moreover, both reduced the CO2 emissions.

The subject of this study is the dispersed composition of multicomponent cement systems. This study aims to reduce interparticle voids, increasing the strength and concentration of the solid phase. The investigated concrete mixture contained two fine aggregate fractions, granite-gabbro crushed stone of 5–10 mm fraction, Portland cement of CEM I 42.5N class, finely dispersed granular blast furnace slag, microsilica, highly dispersed cement fraction, superplasticizer Glenium 430, and high-valence hardening accelerator. A laser analyzer determined the shape and size of dispersed particles of the components. The structure of the cement stone was studied by scanning microscopy, thermographic, and X-ray phase analysis methods. The strength of concrete with an optimized dispersed composition at the age of 2 days was 52, 63, and 74 MPa, while that at the age of 28 days was 128, 137, and 163 MPa. For this concrete, the consumption of multicomponent cement was 650, 700, and 750 kg/m3, respectively. The high efficiency of the application of bimodal clinker component and granulated blast-furnace slag is shown. It is established that the optimal content of nanoscale additives, including microsilica, should be insignificant and determined experimentally.

Summary This project demonstrated the effectiveness of a microbial permeability profile modification (MPPM) technology for enhancing oil recovery by adding nitrogenous and phosphorus-containing nutrients to the injection water of a conventional waterflooding operation. The MPPM technology extended the economic life of the field by 60 to 137 months, with an expected recovery of 63 600 to 95 400 m3 (400,000 to 600,000 bbl) of additional oil. Chemical changes in the composition of the produced fluids proved the presence of oil from unswept areas of the reservoir. Proof of microbial involvement was shown by increased numbers of microbes in cores of wells drilled within the field 22 months after nutrient injection began. Introduction The target for enhanced oil recovery processes is the tremendous quantity of unrecoverable oil in known deposits. Roughly two thirds [approximately 55.6×109 m3 (350 billion bbl)] of all of the oil discovered in the U.S. is economically unrecoverable with current technology. Because the microbial enhanced oil recovery (MEOR) technology in this report differs in several ways from other MEOR technologies, it is important that these differences be delineated clearly. In the first place, the present project is designed to enhance oil recovery from an entire oil reservoir, rather than treat single wells. Even more important is the fact that this technology relies on the action of the in-situ microflora, not microorganisms injected into the reservoir. It is important to note that MPPM technology does not interfere with the normal waterflood operation and is environmentally friendly in that neither microorganisms nor hazardous chemicals are introduced into the environment. Description of the Oil Reservoir. The North Blowhorn Creek Oil Unit (NBCU) is located in Lamar County, Alabama, approximately 75 miles west of Birmingham. This field is in what is known geologically as the Black Warrior basin. The producing formation is the Carter sandstone of Mississippian Age at a depth of approximately 700 m (2,300 ft). The Carter reservoir is a northwest/ southeast trending deltaic sand body, approximately 5 km (3 miles) long and 1 to 1.7 km (1/2 to 1 mile) wide. Sand thickness varies from only 1 m up to approximately 12 m (40 ft). The sand is relatively clean (greater than 90% quartz), with no swelling clays. The field was discovered in 1979 and initially developed on 80-acre spacing. Waterflooding of the reservoir began in 1983. The initial oil in place in the reservoir was approximately 2.54×106 m3 (16 million bbl), of which 874 430 m3 (5.5 million bbl) had been recovered by the end of 1995. To date, North Blowhorn Creek is the largest oil field discovered in the Black Warrior basin. Oil production peaked at almost 475 m3/d (3,000 BOPD) in 1985 and has since declined steadily. Currently, there are 20 injection wells and 32 producing wells. Oil production at the outset of the field demonstration was approximately 46 m3/d oil (290 BOPD), 1700 m3/d gas (60 MCFD), and 493 m3/d water (3,100 BWPD), with a water-injection rate of approximately 660 m3/d (4,150 BWPD). Projections at the beginning of the project were that approximately 1.59×106 m3 oil (10 million bbl of oil) would be left unrecovered if some new method of enhanced recovery were not effective. Prefield Trial Studies The concepts of the technology described in this paper had been proven to be effective in laboratory coreflood experiments.1,2 However, it seemed advisable to conduct coreflood experiments with cores from the reservoir being used in the field demonstration. Toward this end, two wells were drilled, and cores were obtained from one for the laboratory coreflood experiments to determine the schedule and amounts of nutrients to be employed in the field trial.3

Abstract Background Herpes zoster (HZ), caused by reactivation of varicella-zoster virus (VZV), typically manifests as a dermatomal rash and can lead to postherpetic neuralgia (PHN). HZ and PHN risk increase with age. Efficacy against HZ induced by a live-attenuated zoster vaccine (ZVL; Merck) declines following vaccination (21% in years 5–12 post-vaccination). To ensure protection, revaccination can be considered. Therefore, we assessed immunogenicity and safety of HZ/su, a non-live candidate vaccine containing VZV glycoprotein E (gE) subunit and AS01B adjuvant system (GSK), in adults previously vaccinated with ZVL ≥5 years before, (HZ-PreVac) compared with adults not vaccinated with ZVL (HZ-NonVac). Methods In this phase III, group-matched, open, multicenter study (NCT02581410), 2 parallel groups of adults ≥65 years of age (YOA) received 2 HZ/su doses 2 months apart. A co-primary objective was to compare humoral immune responses 1 month post-dose 2 (M3) in the 2 groups (non-inferiority criterion: upper limit [UL] of the 95% confidence interval [CI] for HZ-NonVac/HZ-PreVac adjusted anti-gE antibody geometric mean concentration [GMC] ratio <1.5). Humoral and cellular immune responses were evaluated at various time points. Solicited and unsolicited adverse events (AEs) were recorded for 7 and 30 days post each dose, respectively. Serious AEs (SAEs), HZ cases and potential immune-mediated diseases (pIMDs) will be recorded until study end. Here, we present data up to M3, as the study is still ongoing. Results 430 participants were vaccinated. M3 humoral immune responses in HZ-PreVac were non-inferior to those in HZ-NonVac and the co-primary objective was met as the UL of the 95% CI of the adjusted GMC ratio was 1.17 (Table 1). In addition, there were no apparent differences in CD4[2+] T-cell frequencies between groups (Figure 1). No clinically meaningful differences between frequencies of solicited AEs, unsolicited AEs or SAEs in the 2 groups were observed (Table 2). No SAEs considered vaccine-related by investigators, no suspected HZ cases and no pIMDs were reported up to M3. Conclusion HZ/su vaccination in adults ≥65 YOA who previously received ZVL stimulates strong immune responses and does not raise safety concerns. Funding GlaxoSmithKline Biologicals SA Disclosures K. Grupping, GSK group of companies: Employee, Salary; L. Campora, GSK group of companies: Employee, Salary; M. Douha, GSK group of companies: Employee, Salary; T. C. Heineman, GSK group of companies: Consultant and Shareholder, Consulting fee; N. P. Klein, GSK group of companies: Investigator, Grant recipient sanofi pasteur: Investigator, Grant recipient; Merck & Co: Investigator, Grant recipient; MedImmune: Investigator, Grant recipient; Protein Science: Investigator, Grant recipient; Pfizer: Investigator, Grant recipient; H. Lal, Pfizer: Employee and Shareholder, Salary and Stock as part of compensation; GSK group of companies: Employee at the time of study and Shareholder, Salary and Stock as part of compensation; J. Peterson, GSK group of companies: Investigator, Principal investigator fees; L. Oostvogels, GSK group of companies: Employee and Shareholder, Salary and Shares

Background & Objectives: Since the introduction of erector spinae plane block (ESPB) in 2016 it has been used with success in various thoracic, abdominal, and spine surgeries. Spine surgeries result in significant postoperative pain. Postoperative opioids provide adequate pain control in most of the cases, but some patients continue to suffer from uncontrolled pain. Patients receiving multiple doses of opioids suffer from various side effects including postoperative nausea and vomiting, constipation, and delayed ambulation. We aimed to compare effect of dexmedetomidine and magnesium sulfate given as adjuvants with bupivacaine 0.25% for ESPB. Methodology: It was a prospective randomized single-blinded study including 52 patients divided into 2 groups; one receiving ESPB with a combination of bupivacaine 0.25% plus magnesium sulfate and the other receiving the same block with a combination of bupivacaine 0.25% plus dexmedetomidine. Results: The group receiving bupivacaine and dexmedetomidine had a prolonged postoperative analgesia duration as well as a decreased total opioid consumption (P < 0.05) compared to group receiving bupivacaine 0.25% plus magnesium sulfate, but had a significant decrease in intraoperative pulse rate and blood pressure compared to the group receiving bupivacaine 0.25% plus magnesium sulfate (P < 0.05). Conclusion: Although dexmedetomidine results in prolonged postoperative analgesia duration compared to magnesium sulfate when combined with bupivacaine 0.25% in ESPB, its negative effects on hemodynamics should be considered. Trial registration: This trial was registered on clinicaltrials.gov registry (NCT05694897) on 23/1/2023. Abbreviations: ASA: American Society of Anesthesiologist; ESPB: Erector Spinae Block; ERAS: Enhanced recovery After Surgery; SPSS: Statistical Package for Social Sciences; VAS: Visual Analog Score Key words: Erector Spinae Plane Block; Dexmedetomidine; Bupivacaine; Visual Analog Scale Citation: Refaat SA, Abdelmageed WM, Alwedeny HM, Soliman EH, Fouly MA. A randomized comparative trial of ultrasound guided erector spinae block with bupivacaine-magnesium sulphate vs. bupivacaine-dexmedetomidine for lumbar spine surgeries. Anaesth. pain intensive care 2023;27(5):425−430; DOI: 10.35975/apic.v27i5.2292 Received: July 15, 2023; Reviewed: August 16, 2023; Accepted: August 16, 2023

The disadvantage of high-strength multicomponent concretes is the high absolute and specific consumption of the binder per unit of strength. The object of research is multicomponent cement systems. The subject is the composition of multicomponent cement systems in order to significantly increase the concentration of the solid phase per unit volume, as well as strength and durability. The creation of a dense, highly filled solid phase in the form of heterogeneous mineral modifiers of a homogeneous dispersed structure ensures the production of high strength concretes with a low binder content. Theoretical and practical studies have shown that there are only three levels of dispersion of mineral modifiers, functionally related to the spatial and geometric parameters of the clinker component and its own pozzolanic activity, providing strength and other construction and technical properties of multicomponent cement systems at the maximum level. The properties and structure of concrete were studied using two fractions of fine aggregate, granite-gabro crushed stone fr. 5-10 mm, Portland cement class CEM I 42.5N, finely dispersed blast-furnace granular slag, microsilica, highly dispersed fraction of cement, superplasticizer Glenium 430 and high-valence hardening accelerator. Research methods: the shape and size of dispersed particles of the components were determined by a laser analyzer, the mobility of the concrete mixture in accordance with GOST 10181–2014, the strength of concrete in accordance with GOST 10180–2012. The structure of the cement stone was studied using scanning microscopy, thermographic and X-ray phase analysis methods. The strength of concrete with an optimized disperse composition, a superplasticizer and a high-valence hardening accelerator at the age of 28 days after hardening under normal conditions was 128; 137; 163 MPa, with the consumption of multicomponent cement, respectively 650, 700, 750 kg / m3.

Purpose. To determine the thickness of thin films of coal matter in the Sherubaynurinsky area of the Karaganda basin and their effect on the physical properties of these films. Methodology. In order to calculate the thickness of the surface layer of the coal substance using our proposed formula, one needs to know the molar mass and density. We will use the well-known work where it is shown that such a characteristic as the molecular weight of coal reflects rather well the degree of metamorphism, and is also decisive for the study on the composition and structure of coal raw materials. Findings. The role of the thickness of the surface layer of coal in the course of most physical processes is shown. A thin layer of coal matter differs significantly from metals and other compounds. But it is close to the structure of higher fullerenes. One fundamental parameter, the atomic volume of the surface layer, determines all the properties of the nanostructure of this layer. Originality. For the first time, the thickness of the surface layer of the coal substance has been determined, which is two orders of magnitude greater than the thickness of pure metals. The thickness of the surface layer of higher fullerenes C96 (135 nm) is close to that for OC coal (146 nm). The average statistical structural unit of coal corresponds to higher fullerenes with the number of carbon atoms in the cluster >100, which is a unique feature of coal matter. The thickness of the surface layer of coal in the Sherubaynurinsky area of the Karaganda basin with a size of ~150200 nm was obtained. This structure is a nanostructure. In this layer, the physicochemical properties of nanomaterials occur: a change in the crystalline (supramolecular) structure of coal; a change in its electronic structure and its electrical conductivity; change in the conditions of the stress state of coal; change in the conditions of methane diffusion in coal seams and many other phenomena. Practical value. The natural gas content C0 depends linearly on the reciprocal of d(I). For coal seam k, where d(I) = 180.8 nm, it was obtained 0 = 19 m3/t. After the release of coal and gas, the average value of C0 = 216 m3/t at a seam depth of 430 m, and in the Sherubaynurinsky area C0 = 14 m3/t at an average thickness of the surface layer d(I) = 170 nm. Hence, after the explosion d(I)v = 35 nm, i.e. the layer thickness decreases by almost 5 times, leading to the formation of coal dust. We have considered only a part of the nanostructure issues: porosity and gas content, explosiveness and moisture content of coal seams, and have shown that all physical phenomena in a thin layer of coal have a dimensional dependence and determine structures unexplored until now, and phenomena studies on which are necessary for the practice of mining.

The first 3D-printed building in Spain is the object of this study, and it is presented and physically described herein from different points of view. This study combines on-site measurements, simulations, and a life cycle assessment to assess some relevant parameters concerning the acoustic, thermal and environmental performance of the 3D-printed house. The main objectives are to analyze whether the house complies with the acoustic and thermal regulations and to assess whether it can act as a sustainable alternative to conventional masonry construction, especially when time plays an important role. The build surface (3D prototype) of the house is approximately 23 m2. The internal space includes a living room (12.35 m2), a bedroom (7.36 m2) and a bathroom (3.16 m2). The total surface of the house is 22.87 m2 and it has a volume of 64.03 m3. The acoustic insulation was measured according to the ISO 9869-1:2014 standard. In terms of the acoustic insulation, the sound reduction index was tested following the guidelines of the ISO 140-5:1999 standard. Additionally, the study includes a comparative life cycle assessment comparing the 3D-printed façade with two conventional wall typologies. The 3D-printed house displays an excellent thermal performance, with a measured thermal transmittance of 0.24 Wm−2K−1, suitable for all Spanish climate zones. Regarding the acoustic insulation, the measured global sound reduction indexes of the façades range from 36 to 45 dB, which is adequate for areas with noise levels of up to 75 dB. The environmental results indicate that 3D-printed façade manufacturing emits 30% more CO2e than a façade constructed using concrete blocks and 2% less than a masonry block wall. Overall, this study shows that, in addition to its multiple advantages in terms of the construction time, the studied 3D-printed house has similar acoustic, thermal and environmental traits to the most common construction typologies. However, it cannot be considered a sustainable construction method due to its high amount of cement.

Introduction. Significant disadvantages of currently used high-strength concrete are the high absolute consumption of binder as well as its low specific consumption per unit of strength. Including many components with the goal of multi-level optimization of the dispersed composition is one of the main methods for producing high-strength concretes with a minimum content of cement and high physical and mechanical properties. Obtaining such concretes can be connected with creating a dense high-aggregated solid phase of the constituents at various structural levels and low water-to-cement ratio. Materials and methods. he following components were used to study the properties and structure of the concrete: two fine aggregate fractions, granite-gabbro crushed stone of 5 to 10 mm fraction, portland cement of the CEM I 42.5N class, finely dispersed blast furnace granulated slag, metakaolin, silica fume, high-dispersed cement fraction, Glenium 430 superplasticizer, and high-valent hardening accelerator. The shape and size of the dispersed particles of the components were determined using a laser analyzer, the flowability of the concrete mixture was evaluated as per GOST 10181-2014 standard, while the concrete compressive strength following GOST 10180-2012 standard. The cement stone structure was studied using derivatographic analysis and x-ray phase analysis methods. Results. For concrete with an optimized dispersed composition, superplasticizer and high-valent hardening accelerator prepared using self-compacting concrete mixtures, the concrete strength at the age of 1 day after hardening was of 58,67 and 77 MPa and at the age of 28 days after hardening was of 150, 186 and 219 MPa under normal conditions and with cement consumption of 650, 710 and 770 kg/m3, respectively. Conclusions. Multi-level dispersion and granulometric modification in combination with chemical modification of the composition of self-compacting concrete mixtures is one of the most productive directions of research and synthesis of high-strength concrete with minimum consumption of Portland cement and high physical and mechanical properties. It is advisable to use several structural levels of the clinker component particles.

Introduction. The toxic and hygienic assessment of both the final product and intermediate synthesis products remains the key preventive measure to avoid intoxication of workers’ body by industrial xenobiotics in the chemical and pharmaceutical industry and in the context of a constant increase in the range of used compounds. In recent years, nitrogen-containing heterocyclic compounds of the pyridine group have been widely used in various industries. One of these substances is the anti-tuberculosis drug ethionamide, the intermediate product in the synthesis of which is 2-ethyl-4-nitropyridine N-oxide. Materials and methods. In experiments, the toxic properties of 2-ethyl-4-nitropyridine N-oxide were studied. The investigations were carried out on outbred rats and mice, rabbits and guinea pigs. The effect of the substance on experimental animals was assessed using standard physiological, biochemical, hematological and morphological indices. Intermediate toxicity was studied with different methods of substance administration (oral, percutaneous and inhalation) both in single and repeated experiments. The obtained results were processed using the Statistic 10.0 software package. Results. Mean lethal doses of 2-ethyl-4-nitropyridine N-oxide for female rats and male mice were 1250 mg/kg (976.6÷1600.0 mg/kg) and 430 mg/kg (355.4÷520.3mg/kg), respectively; for female mice - 675 mg/kg. The ability of the substance to accumulate was average: the cumulation coefficient was 4.0. There were no significant differences in the effect of the substance on animals of different species and gender. The substance didn’t show a local irritating effect on the skin, skin-resorptive and allergic effects, but a pronounced irritating effect on the mucous membranes of the eyes was revealed. In the subacute experiment, 2-ethyl-4-nitropyridine N-oxide showed a toxic effect mainly on the blood system. A specific damaging effect was revealed, which was expressed in an imbalance of the content of oxyhemoglobin and methemoglobin with a significant increase in the latter. The threshold index of acute inhalation effect was 76.7 mg/m3. The tentative safe exposure level in the air of the working area for the substance was calculated at the level of 0.5 mg/m3. Limitations. The investigation is limited to the study of the toxicological characteristics of 2-ethyl-4-nitropyridine N-oxide. In accordance with the directive documents on the protection of experimental animals, the limited number of in vivo experiments is connected with the dangers for animals and with public ethical views on in vivo experiments. Conclusion. The proposed tentative safe level of exposure to 2-ethyl-4-nitropyridine N-oxide in the air of the working area at the level of 0.5 mg/m3 makes it possible to attribute the xenobiotic to hazard class II. Under the conditions of compliance with the specified standard, the dose absorbed by the worker under the production conditions will be no more than 5-10 mg per work shift, which guarantees safety for health and minimizes the risk to the health of workers. Information on the toxicity of 2-ethyl-4-nitropyridine N-oxide can be useful for solving a wide range of tasks fixed in the control and supervisory activities of the Federal Service for Supervision in Protection of the Rights of Consumer and Man Wellbeing, hygienic rationing and monitoring, and will contribute to the prevention and reduction of incidence rate associated with the exposure to harmful factors of the production environment.

Abstract. Aiman WM, Yusoff FM, Arshad A, Kamal AHM, Ismail J, Idris MH, Karim NU, Asif AA. 2020. Distribution of zooplankton community in Toli shad (Tenualosa toli) habitats, Sarawak, Malaysia. Biodiversitas 21: 4022-4033. The river ecosystems of Sarawak has been identified as important-spawning ground for economically important Toli shad (Tenualosa toli) fisheries. In these river ecosystems, zooplankton serves as a secondary producer to the different types of fish larvae including Toli shad. The productivity and biomass of zooplankton are important factors to control the production of higher trophic level organisms like fish larvae and fishes in different stages including T. toli larvae. In this viewpoint, the composition and abundance of zooplankton were investigated at 5 (five) sampling stations (considered to be spawning and nursing areas of Toli shad) at Batang Lupar and Batang Sadong estuaries from July 2016 to June 2017. A total of 29 zooplankton taxa were recorded that belong to 14 major groups comprised of Copepoda (Arthropoda), Crustacean nauplii (Arthropoda), Fish larvae (Chordata), Mollusca (Mollusca), Luciferidae (Arthropoda), Cnidaria (Cnidaria), Ostracoda (Arthropoda), Cirripedia (Arthropoda), Polychaete larvae (Annelida), Chaetognatha (Chaetognatha), Appendicularia (Chordata), Amphipoda (Arthropoda), Echinodermata larvae (Echinodermata) and Cladoceran (Arthropoda). Copepod was dominant group of zooplankton (82.40-94.41%) at all stations, contributing 477.37-25921.89 ind/m3 and 88.38% of total abundance. The second highest was crustacean larvae (2.45-9.38%) in all stations, contributing 0-2391.7 ind/m3 and 5.88% of total abundance. Zooplankton abundance was higher at downstream station 1 (8460.72 ind/m³) followed by station 2 (5479.80 indi/m³), station 3 (4571.95 ind/m³), station 4 (4394.20 ind/m³) and upstream station 5 (4156.73 ind/m³). Canonical Correspondence Analysis showed that the abundance of copepods was highly influenced by total turbidity and nitrate in the riverine and estuarine ecosystems. Abundance of zooplankton was relatively higher (9549.31 ind/m³) during the post-monsoon and lower (3534.56 ind/m³) during the southwest monsoon.

BACKGROUND: Fine particulate matter (PM2.5) is a risk factor for stroke, and patients with pre-existing diseases appear to be particularly susceptible. We conducted a case-crossover study to examine the association between short-term exposure to fine particulate matter (PM2.5) and hospital admission for stroke in individuals with atrial fibrillation (AF), hypertension, diabetes, or hyperlipidemia. METHODS: Patients diagnosed with acute ischemic stroke (AIS) were recruited from 2015 to 2017 in Chinese Stroke Center Alliances. We estimated daily PM2.5 average exposures with a spatial resolution of 0.1° using a data assimilation approach combining satellite measurements, air model simulations, and monitoring values. Conditional logistic regression was used to assess PM2.5-related stroke risk in patients with pre-existing medical co-morbidities. RESULTS: A total of 155 616 patients diagnosed with AIS were admitted. Patients with a history of AF (n=15 430), hypertension (n=138 220), diabetes (n=43 737), or hyperlipidemia (n=16 855) were assessed separately. A 10 µg/m3 increase in daily PM2.5 was associated with a significant increase in AIS for individuals with AF at lag 4 (OR, 1.008; 95% CI, 1.002-1.014), and with hypertension (OR, 1.008; 95% CI, 1.006-1.010), diabetes (OR, 1.006; 95% CI, 1.003-1.010), and hyperlipidemia (OR, 1.007; 95% CI, 1.001-1.012) at lag 0-7. Elderly (≥65 years old) and female patients with AF had significantly higher associations at lag 5 (OR, 1.009; 95% CI, 1.002-1.015) and lag 5 (OR, 1.010; 95% CI, 1.002-1.018), respectively. CONCLUSIONS: Short-term exposure to PM2.5 is significantly associated with hospital admission for stroke in individuals with pre-existing medical histories, especially in older or female patients with AF. Preventative measures to reduce PM2.5 concentrations are particularly important in individuals with other medical co-morbidities.

On Moneron Island actively develops avalanche, debris-flow and landslide processes. Avalanches with a volume from 25 to 70 000 m3 are formed in avalanche catchments and avalanche slopes with a height of 70-300 m and a steepness of 35°-50°. Avalanches are formed that are associated with recrystallization of the snow column and the formation of weak layers inside it and at time during of snow fall and blizzard. Debris-flow are formed in the numerous streams, in the craters of denudation and landslide cirques and troughs. In small watercourses, connected debris-flows with a volume from 300 to 50 000 m3 and disconnected suspended streams with a volume of up to 1,000 m3 are formed. In large debris-flow are volume more them 50,000 m3. The debris-flow period lasts from April to November. Repeatability of debris-flows of up to 3,000 m3 – 1 time in 5-7 years, debris-flows of more than 10,000 m3 – 1 time in 10-12 years. Surface landslides are formed (volume of 500-5 000 m3) with a depth of capture of rocks up to 2.5 m (mainly on the slopes facing the sea coast with a steepness of 40-50°) in low-power (1.0-2.5 m) deluvial loose deposits of fractured basalts and mudstones. Block landslides in rocks with a volume of 50 000-500 000 m3 or more with a rock capture depth of more than 10 m are formed on the coastal slopes. Block landslides descend during earthquakes and (or) heavy prolonged rains into the sea area and can cause tsunamis that can reach the shores of Sakhalin Island, Hokkaido and the Maritime provinces. On the bodies of old landslides secondary block asequent landslides of slow displacement and landslides of viscoplastic displacement with a volume of 5 000-30 000 m3 with a depth of rock capture up to 10 m develop. The formation of landslides and debris-flows of large volumes and mass formation of landslides and debris-flows occurs when heavy intense precipitation falls after the previous moistening of rocks caused by heavy prolonged rains. Daily precipitation can reach 89.0 mm. In 1914, 4 people was killed in an avalanche in the village of Nagahama; in 1917, 1 person was killed in an avalanche in the village of Nishihama. In September 1957, a landslide destroyed the village of Bodriy. In October 2015, a tourist trail was destroyed by landslides. References Atlas snezhno-ledovykh resursov mira v 2 t. Tom 2: v 2 kn. Kniga 1 [World Atlas of Snow and Ice Resources in 2 volumes. Volume 2: in 2 books. Book 1]. Kotlyakov V.M. (ed.). Moscow, Publ. of General Directorate of Geodesy and Cartography, 1998. 264 p. (In Russian). Atlas Sakhalinskoi oblasti [Atlas of the Sakhalin Region]. Komsomol'skii G.V., Siryk I.M. (eds.). Moscow, Publ. of General Directorate of Geodesy and Cartography, 1967. 135 p. 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Представлены основные результаты проведённых исследований лавинных, селевых и оползневых процессов острове Монерон. Лавины всех генетических типов объёмом от 25 до 70 000 м3 формируются с декабря по апрель. Связные грязекаменные сели объёмом от 300 до 50 000 м3 и несвязные сели (наносоводные потоки) объёмом до 1000 м3 формируются с апреля по ноябрь в бассейнах водотоков, в денудационных воронках, в оползневых цирках и мульдах. Повторяемость селей объёмом до 3 000 м3 – 1 раз в 5-7 лет, селей объёмом более 10 000 м3 – 1 раз в 10-20 лет. Формируются поверхностные оползни-оплывины (сплывы) объёмом 500-5 000 м3 с глубиной захвата до 2,5 м делювиальных рыхлых отложений, залегающих на миоцен-плиоценовых трещиноватых базальтах и аргиллитах. На береговых склонах формируются блоковые оползни в скальных породах объёмом 50 000-500 000 м3 и более с глубиной захвата пород более 10 м. Блоковые оползни сходят во время землетрясений и (или) сильных продолжительных дождей в морскую акваторию и способны вызывать цунами, которые могут достигать берегов островах Сахалин, Хоккайдо и Приморья. На телах старых оползней развиваются вторичные блоковые асеквентные оползни медленного смещения и оползни вязкопластического смещения объёмом 5 000-30 000 м3 с глубиной захвата пород до 10 м. Формирование оползней и селей больших объёмов и массовое формирование оползней и селей происходит в июле-октябре при выпадении сильных интенсивных осадков после предшествующего увлажнения горных пород, вызванного сильными продолжительными дождями. Суточная сумма осадков может достигать 89,0 мм. На острове Монерон происходили катастрофы, вызванные сходом лавин и оползней. В 1914 г. в деревне Нагахама (восточное побережье острова) в лавине погибло 4 человека; в 1917 г. в деревне Нишихама (западное побережье острова) в лавине погиб 1 человек. В сентябре 1957 г. оползнем был разрушен посёлок Бодрый. 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A doença mão-pé-boca é uma infecção viral, normalmente benigna que afeta comumente crianças até 10 anos, causada pelos enterovírus humano. O propósito deste estudo foi revisar os aspectos da doença que se faz presente nos dias atuais abordando a etiologia, epidemiologia, surtos, sintomatologia e comorbidades, diagnóstico, prevenção e tratamento. Foram selecionadas publicações em periódicos referenciados nas fontes de dados do Google Acadêmico, Pubmed e Periódicos Capes com as palavras chaves relacionadas ao tema desse trabalho como doença mão-pé-boca e crianças, sendo selecionados artigos produzidos até 2017. Apesar de diagnóstico clínico aparentemente simples, a doença pode ser confundida com outras enfermidades por suas características semelhantes, que podem induzir o colega odontólogo ao equívoco de diagnóstico.Descritores: Doença de Mão, Pé e Boca; Diagnóstico, Odontopediatria.ReferênciasSarkar PK, Sarker NK, Tayab A. Hand, foot and mouth disease (hfmd):an update. 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