Bibliografie tematiche / Urine humaine

Letteratura scientifica selezionata sul tema "Urine humaine"

Autore: Grafiati

Pubblicato: 1 giugno 2024

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Articoli di riviste sul tema "Urine humaine":

Brun, Florent, Steve Joncoux, Bernard de Gouvello e Fabien Esculier. "Vers une valorisation des urines humaines". Études rurales, n. 206 (1 dicembre 2020): 200–220. http://dx.doi.org/10.4000/etudesrurales.24043.

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Sosvorová, L., P. Lanková, M. Bičíková, E. A. Prokudina, N. Al Malarik e O. Lapčík. "ELISA for free S-equol in human urine". Czech Journal of Food Sciences 29, No. 1 (14 febbraio 2011): 57–64. http://dx.doi.org/10.17221/130/2010-cjfs.

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The popularity of phytoestrogen food supplements of plant origin steadily increases. They are used to solve the problems related to the climacterium. Their efficiency depends on woman's capability to metabolise the active components – isoflavonoids. Women able to convert daidzein to S-equol are supposed to get a greater benefit from these supplements. To determine S-equol urine levels, the competitive ELISA was developed. Carboxymethylequol coupled to BSA via 4'-O-position was used as an immunogen. The assay conditions, including the concentrations of the coating antigen and antisera, were optimised. The detection limit was 0.1 ng/ml (5 pg/well) and 50% intercept was 1 ng/ml (50 pg/well). The intraassay coefficients of variation (CV) varied from 4.7% to 9.9%, for the interassay CV the corresponding values of 2.6–11.6% were obtained. The recovery of the standard added to urine ranged between 89% and 104%. All examined samples were obtained from women in climacterium. The volunteers had been taking phytoestrogen food supplements for 3 months. The urine samples were collected before and after the therapy. The levels of free urinary S-equol after the therapy ranged between 0 ng/ml and 42.4 ng/ml. The equol production was observed in 57% of the examined patients. The laboratory results were confronted with patients' subjective evaluations.

Starykovych, M., S. Souchelnytskyi, O. Fayura, O. Abrahamovych, M. Abrahamovych, N. Lukavetskyy, R. Stoika e Y. Kit. "Identification of cortactin molecular forms in human urine and their possible diagnostic value". Ukrainian Biochemical Journal 93, n. 4 (13 settembre 2021): 103–10. http://dx.doi.org/10.15407/ubj93.04.103.

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Mohamed, Marwa El Badry, Eman Y. Z. Frag, Hana A. El-Boraey e Safa S. El-Sanafery. "Extractive Spectrophotometric Methods for Determination of Chlorpheniramine Maleate in Pure Form, Pharmaceutical Preparations and Biological Fluids". International Letters of Chemistry, Physics and Astronomy 75 (agosto 2017): 11–24. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.75.11.

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In this study a simple, rapid and sensitive spectrophotometric method was developed for the determination of an antihistaminic drug chlorpheniramine maleate (CPM) in pure form, pharmaceutical preparations, spiked humane urine and spiked blood serum. This method was based on the formation of ion-pairs between the basic nitrogen of the CPM drug and four chromogenic reagents namely bromocresol purple (BCP), alizarine Red S (ARS), eriochrome cyanine R (ECR), and cresol red (CR). The extracted colored ion-pairs were measured spectrophotometrically at 390, 425, 503 and 408 nm for BCP, ARS, ECR and CR reagents, respectively. The different parameters that affect the color development between CPM drug and dyestuff reagents were extensively studied to determine the optimal conditions for the assay procedure. The reaction was studied as a function of the volume of reagents, nature of solvent, temperature, reaction time and stoichiometric ratio between the CPM drug and the reagents. Beer’s law was valid over the concentration ranges of 1-30, 1-10, 2-120 and 4-120 μg mL-1 of CPM drug using BCP, ARS, ECR and CR reagents, respectively. The Sandell sensitivity, molar absorptivity, limit of detection and limit of quantification were determined. Applications of the proposed procedure to the analysis of the pharmaceutical preparations, spiked humane urine and spiked blood serum gave reproducible and accurate results without any interference from excipients. The results obtained by the proposed method were in good agreement with those obtained by reported method. The method can be suggested for the routine analysis of the cited drug.

Mohamed, Marwa El Badry, Eman Y. Z. Frag, Hana A. El-Boraey e Safa S. El-Sanafery. "Extractive Spectrophotometric Methods for Determination of Chlorpheniramine Maleate in Pure Form, Pharmaceutical Preparations and Biological Fluids". International Letters of Chemistry, Physics and Astronomy 75 (17 agosto 2017): 11–24. http://dx.doi.org/10.56431/p-1e5rn8.

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Mohaupt e von Vigier. "Hormonanalysen im Urin". Therapeutische Umschau 63, n. 9 (1 settembre 2006): 559–64. http://dx.doi.org/10.1024/0040-5930.63.9.559.

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Hormonanalysen im Urin werden vorwiegend angewendet, um Störungen des Steroidhormonmetabolismus, um eine erhöhte Produktion biogener Amine und um nicht invasiv humanes β-Choriogonadotropin als Proteinhormon als Indikator einer Schwangerschaft nachweisen zu können. Diese Untersuchungen müssen gegebenenfalls von Plasma-/ Serumbestimmungen komplementiert werden. Klinische Daten einschließlich der aktuellen Medikation sowie das Urinkreatinin als Bezugsgröße sind unabdingbar zur seriösen Beurteilung einer Urinuntersuchung. Die wichtigsten Krankheitsbilder, die mittels Steroidhormonanalyse untersucht werden können, sind der Exzess eines typischen oder atypischen mineralokortikoid wirksamen Steroidhormons, die Hormonaktivität eines Nebennieren- oder ovariellen Tumors, Akne unklarer Ätiologie, Hirsutismus, ein PCO-, ein adrenogenitales oder ein vermutetes Cushingsyndrom. Die Untersuchung biogener Amine wird durchgeführt bei Verdacht auf eine sekundäre bzw. therapierefraktäre Hypertonie, bei Auftreten phäochromozytom- oder paragangliom-assoziierter Symptome oder Verdacht auf einen serotininproduzierenden Tumor. Bei Kindern steht die Suche nach genetisch determinierten Erkrankungen im Vordergrund.

Hancock, D. D., T. E. Besser, M. L. Kinsel, P. I. Tarr, D. H. Rice e M. G. Paros. "The prevalence ofEscherichia coliO157.H7 in dairy and beef cattle in Washington State". Epidemiology and Infection 113, n. 2 (ottobre 1994): 199–207. http://dx.doi.org/10.1017/s0950268800051633.

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SUMMARYEscherichia coliO157.H7 was found in 10 of 3570 (0·28%) faecal samples from dairy cattle in 5 of 60 herds (8·3%). Several tentative associations with manure handling and feeding management practices on dairy farms were identified. Faecal/urine slurry samples, bulk milk samples, and milk filters from dairy herds were negative forE. coli0157.H7.E. coli0157.H7 was also isolated from 10 of 1412 (0·71 %) faecal samples from pastured beef cattle in 4 of 25 (16%) herds. The prevalence ofE. coli0157. H7 excretion in feedlot beef cattle was 2 of 600 (0·33 %). The identification of cattle management practices associated with colonization of cattle byE. coli0157.H7 suggests the possibility that humanE. coliO157.H7 exposure may be reduced by cattle management procedures.

Mure, P. Y., T. Gelas, M. Benchaib, F. Dijoud, A. Feyaerts, T. Roger e P. Mouriquand. "Conséquences hémodynamiques des anomalies congénitales de l'écoulement des urines : du modèle animal au modèle humain". Archives de Pédiatrie 13, n. 6 (giugno 2006): 725–27. http://dx.doi.org/10.1016/j.arcped.2006.03.029.

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D. Marhash, Ali, Qasim S. Al-Mayah e Enas A.A. Al-Kazaaly. "Detection and Phylogenetic Analysis of Human Papilloma Virus in Urine from a Sample of Iraqi Women with Vaginal Discharge". Journal of Pure and Applied Microbiology 12, n. 4 (30 dicembre 2018): 2183–92. http://dx.doi.org/10.22207/jpam.12.4.57.

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Khasraw Ali, Dashty, Nabil Adil Fakhre e Chnar Mohameed Rasheed. "Ratio derivative-zero crossing and successive derivative of ratio spectra for simultaneous determination of urea, creatinine, and uric acid in human urine samples". Bulletin of the Chemical Society of Ethiopia 37, n. 4 (12 maggio 2023): 817–29. http://dx.doi.org/10.4314/bcse.v37i4.2.

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ABSTRACT. Two simple precise and accurate spectrophotometric techniques are developed for simultaneous determination of ternary mixture of urea, creatinine, and uric acid in humane urine sample. The first technique is a ratio derivative zero - crossing where measured urea at 216.61 nm, creatinine at 260.56 nm, and uric acid at 283 nm. The second technique is a successive derivative of ratio spectra where urea, creatinine, and uric acid measured at 203 nm, 261 nm, and 283 nm, 287 nm, respectively. These procedures do not need separation. The proposed methods showed excellent linear range over the concentration ranges of 1.0–15.0 μg/mL, 1.0–16.0 μg/mL, and 2.0–15.0 μg/mL for urea, creatinine, and uric acid, respectively. The recoveries ranged from 97.10% to 101.9% for urea, 97.22% to102.70 % for creatinine, and 97.45% to102.55 % for uric acid with relative standard deviations less than 1.56% for urea, 3.87% for creatinine, and 3.71% for uric acid. The analytical eco-scale and green analytical procedure index tools were used to evaluate how the proposed procedures will affect the environment. The simultaneous quantification of urea, creatinine, and uric acid in human urine samples can be accomplished with remarkable effectiveness by using the suggested approaches. KEY WORDS: Urea, Creatinine, Uric acid, Derivative spectrophotometry Bull. Chem. Soc. Ethiop. 2023, 37(4), 817-829. DOI: https://dx.doi.org/10.4314/bcse.v37i4.2

Più fonti

Tesi sul tema "Urine humaine":

LOUTFI, HAMID. "L'antiprotease acido-stable de l'urine humaine : etude structurale et determination chez le sujet sain et en cas de proteinurie". Lille 2, 1990. http://www.theses.fr/1990LIL2P253.

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Martin, Tristan. "L’urine humaine en agriculture : des filières variées pour contribuer à une fertilisation azotée durable". Electronic Thesis or Diss., université Paris-Saclay, 2020. http://www.theses.fr/2020UPASB026.

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Pour nourrir les humains, l’agriculture actuelle est fortement tributaire de l’utilisation de fertilisants issus de ressources fossiles. Or la majorité des nutriments de l’alimentation est ensuite excrétée dans les urines. Celles-ci sont usuellement mélangées aux eaux usées dont la gestion ne permet qu’un faible recyclage de ces nutriments et entraîne de nombreux impacts environnementaux. L’objectif de cette thèse est de caractériser les filières envisageables de valorisation de l’urine humaine en agriculture au niveau agronomique et de leurs impacts environnementaux. Une revue de la littérature des différents traitements de l’urine et des urinofertilisants obtenus montre que : (i) l'efficacité agronomique de la plupart des urinofertilisants est haute et nécessite d’être davantage étudiée ; (ii) la majorité des pathogènes peuvent être facilement inactivés, les résidus de pharmaceutiques sont plus difficilement dégradés ; (iii) la consommation d'énergie et de réactifs des traitements peut être élevée. L’efficacité fertilisante d’une dizaine d’urinofertilisants a ensuite été mesurée au champ et en serre. Elle est élevée pour la majorité et proche de celle des engrais minéraux (équivalence engrais de 52% à 120%). Elle est liée à une forte teneur en azote minéral dans la majorité des urinofertilisants. La volatilisation ammoniacale peut potentiellement être importante (e.g. 34% de l‘azote en conditions propices), le pH élevé et la teneur en azote ammoniacal, selon les urinofertilisants, étant des facteurs de risque importants. Enfin, une évaluation par analyse du cycle de vie des impacts environnementaux associés à la production de céréales a été réalisée selon le mode de fertilisation : biologique et conventionnelle versus trois urinofertilisants. Les impacts sont plus faibles pour la majorité des indicateurs en comparaison aux pratiques actuelles, en grande partie grâce aux impacts évités de l’épuration des eaux usées et de la production d’engrais minéraux. La volatilisation ammoniacale et la consommation d’énergie des traitements sont les deux éléments les plus sensibles du bilan environnemental. Ces résultats montrent que le déploiement de filières de valorisation de l’urine humaine peut contribuer à une transition vers une gestion systémique et soutenable des nutriments
To feed humans, agriculture mostly relies on the use of fertilizers derived from fossil resources. Yet, most nutrients from food are excreted in urines and mixed in wastewaters. Wastewater treatment allows only a weak recycling of the nutrients and has many environmental impacts. The objective of this thesis is to characterize the possible management options for the use of human urine in agriculture considering their fertilizing efficiency and their environmental impacts. A literature review of the various urine treatments and urine-based fertilizers shows that: (i) the fertilizing efficiency of most urine-based fertilizers is high but needs to be further studied; (ii) most pathogens in urine can be easily inactivated but pharmaceutical residues are more difficult to degrade; (iii) the energy and chemical consumption of treatments can be high. The fertilizing efficiency of ten urine-based fertilizers has been measured under greenhouse and field conditions. It is high for most of the urine-based fertilizers and close to that of mineral fertilizers (equivalent ranging from 52% to 120%). It is linked to high mineral nitrogen content in the majority of urine-based fertilizers. Ammonia volatilization after field application can potentially be high (e.g. 34% of total nitrogen in favorable conditions). High pH and ammoniacal nitrogen content according to the urine-based fertilizers are important risk factors. Finally, a life cycle assessment of the environmental impacts for cereal production was carried out considering three urine-based fertilizers and two agricultural systems (conventional and organic). The impacts are lower for the majority of the indicators compared to the current practices. It is mainly due to the avoided impacts due to wastewater treatment and mineral fertilizers synthesis. Ammonia volatilization and the energy consumption of the treatments appear as the main environmental hotspots. These results show that the implementation of human urine management options can contribute to a transition towards a more sustainable and systemic management of nutrients

Klein, Marlène. "Identification et quantification de métabolites séléniés dans l’urine humaine". Pau, 2010. http://www.theses.fr/2010PAUU3034.

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La barrière entre l’aspect bénéfique du sélénium (Se) et son aspect toxique est étroite. Afin de mieux contrôler les apports de cet élément dans l’alimentation, de nombreux travaux s’intéressent à la compréhension de son métabolisme. Cette thèse présente le développement et l’optimisation de méthodes d’analyse des espèces séléniées dissoutes et volatiles présentes dans l’urine de sujets non supplémentés. Le couplage entre la chromatographie liquide et la spectrométrie de masse atomique précédé d’un prétraitement de l’échantillon par extraction sur phase solide a permis non seulement de confirmer la présence de métabolites séléniés précédemment détectés dans l’urine de sujets supplémentés mais également, de mettre en évidence des composés inconnus. Un de ces composés a été identifié par spectrométrie de masse moléculaire. Les couplages entre la chromatographie gazeuse et les spectrométries de masse atomique et moléculaire, précédés d’une micro-extraction sur phase solide ont été utilisés pour l’analyse des formes volatiles de Se. Ces méthodes ont permis de confirmer la présence de composés séléniés et mixtes Se/S dans les urines de sujets non supplémentés et, de définir des conditions de stockage permettant de préserver la spéciation originelle dans l’échantillon
The concentration range between beneficial and toxic effects for selenium (Se) is very narrow. In order to monitor selenium intake and to improve knowledge of Se metabolism, studies on selenium species ingested and excreted are performed. This report presents the development and the optimization of speciation analysis of dissolved and volatile Se species in urine of non supplemented subjects by coupling liquid chromatography or gas chromatography to inductively coupled plasma mass spectrometry. In the case of dissolved species, solid phase extraction of the sample as sample pretreatment allowed us to confirm the presence of known selenium compounds and to highlight unknown selenium species. One of these new species was further identified by molecular mass spectrometry. The analysis of volatile selenium compounds was performed by gas chromatography coupled to ICP-MS after sample extraction by SPME. This method led to the identification of some selenium and mixed selenium/sulphur species in urine from non supplemented subjects and allowed us to define suitable storage conditions to maintain original speciation

Klein, Marlène. "Identification et quantification de métabolites séléniés dans l'urine humaine". Phd thesis, Université de Pau et des Pays de l'Adour, 2010. http://tel.archives-ouvertes.fr/tel-00601535.

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La barrière entre l'aspect bénéfique du sélénium (Se) et son aspect toxique est étroite. Afin de mieux contrôler les apports de cet élément dans l'alimentation, de nombreux travaux s'intéressent à la compréhension de son métabolisme. Cette thèse présente le développement et l'optimisation de méthodes d'analyse des espèces séléniées dissoutes et volatiles présentes dans l'urine de sujets non supplémentés. Le couplage entre la chromatographie liquide et la spectrométrie de masse atomique précédé d'un prétraitement de l'échantillon par extraction sur phase solide a permis non seulement de confirmer la présence de métabolites séléniés précédemment détectés dans l'urine de sujets supplémentés mais également, de mettre en évidence des composés inconnus. Un de ces composés a été identifié par spectrométrie de masse moléculaire. Les couplages entre la chromatographie gazeuse et les spectrométries de masse atomique et moléculaire, précédés d'une micro-extraction sur phase solide ont été utilisés pour l'analyse des formes volatiles de Se. Ces méthodes ont permis de confirmer la présence de composés séléniés et mixtes Se/S dans les urines de sujets non supplémentés et, de définir des conditions de stockage permettant de préserver la spéciation originelle dans l'échantillon.

Esculier, Fabien. "Le système alimentation/excrétion des territoires urbains : régimes et transitions socio-écologiques". Thesis, Paris Est, 2018. http://www.theses.fr/2018PESC1028/document.

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L’alimentation et l’excrétion constituent deux besoins physiologiques fondamentaux de tout être humain. En analysant leur matérialisation depuis l’échelle cellulaire jusqu’à celle des grands cycles biogéochimiques planétaires, nous proposons de considérer que l’alimentation et l’excrétion humaines participent d’un système dont les modalités de réalisations dans les différentes sociétés humaines permettent de caractériser des régimes socio-écologiques. Nous avons plus particulièrement analysé les systèmes alimentation/excrétion des territoires urbains au regard de leur soutenabilité et proposons une méthodologie de caractérisation fondée principalement sur l’analyse du flux de la substance qui nous paraît la plus pertinente, à savoir l’azote, et sur les modalités de gestion des urines humaines qui représentent près des trois quarts de ce flux. Nous montrons que les systèmes alimentation/excrétion des différentes communautés humaines présentent une très grande variété selon les lieux et époques considérés et proposons de les distinguer entre autres en fonction de leur circularité, c’est-à-dire par le taux de retour sur des sols agricoles des excrétats. En prenant l’agglomération parisienne comme cas d’étude, nous montrons que son système alimentation/excrétion a été de plus en plus circulaire au cours du XIXe siècle, culminant au tout début du XXe siècle aux alentours de 50 % de circularité, avant de se linéariser progressivement au cours du XXe siècle. En ce début de XXIe siècle, nous caractérisons le système alimentation/excrétion de l’agglomération parisienne comme non soutenable car linéaire à plus de 95 %, intensif, inefficace et polluant aux échelles locales et globales. Ces caractéristiques sont généralisées au sein du monde occidental et interpellent sur la possibilité d’une transition socio-écologique vers des systèmes alimentation/excrétion soutenables. Or, depuis les années quatre-vingt-dix, une prise de conscience relative à l’urine a réémergé, principalement en Suède puis dans l’Europe germanique. Elle s’est traduite par de nombreuses réalisations et recherches autour de la séparation à la source des urines. Nous montrons que ce dispositif est actuellement le seul, dans le monde occidental, à avoir permis de nouveau la mise en œuvre de systèmes alimentation/excrétion circulaires. Pouvant être déclinée sous de multiples formes en fonction des contextes, la séparation à la source des urines bénéficie, malgré le verrouillage socio-technique de l’agglomération parisienne autour du tout-à-l’égout, d’un contexte favorable à son développement. Nous avons élaboré un scénario prospectif explorant ainsi la possibilité que l’agglomération parisienne dépasse, en quelques décennies, l’extremum de circularité qu’elle avait connu à la Belle Époque et que les acteurs de ce territoire réalisent, en cohérence avec une transition socio-écologique des autres systèmes énergétiques, hydrauliques et de transport, un régime socio-écologique soutenable de leur système alimentation/excrétion. Cette thèse fait partie du programme de recherche et action OCAPI (www.leesu.fr/OCAPI)
Nutrition and excretion are fundamental physiological needs for all human beings. Analysis of their materiality, from the cellular scale up to the great planetary-scale biogeochemical cycles, shows that nutrition and excretion form a system. The focus of our study is the sustainability of the nutrition/excretion systems of urban areas, which we have sought to assess by analysing substance flows. The most relevant of these substances seems to be nitrogen, so by assessing urban nitrogen flows we can characterise the different possible socioecological regimes and their sustainability. We identify a wide diversity of nutrition/excretion systems depending on the places and eras considered. We propose to distinguish them in terms of their circularity, in other words by the rate at which nitrogen from excreta returns to agricultural land. Using the Paris urban area as our case study, we show that its nutrition/excretion system became increasingly circular in the 19th century, reaching maximum circularity right at the start of the 20th century, before becoming steadily more linear in the course of the 20th century. In these early years of the 21st century, the nutrition/excretion system of the Paris urban area is essentially linear, and still generates significant pollution at both local and global scales. Its environmental footprint is exacerbated by a diet that is very protein rich, mostly animal in origin, and by the non-consumption of a significant proportion of the food produced. All these factors make it unsustainable. These characteristics are found throughout the Western world and raise questions about the possibility of a socioecological transition to sustainable systems of nutrition and excretion. Since the 1990s, initially in Sweden, followed by Nordic and German-speaking Europe, awareness has been growing of the role of urine. Urine is responsible for three-quarters of urban nitrogenous excretions and is a safe substance: following a period of storage, it can be used as agricultural fertiliser. This new awareness has been followed by extensive experimentation and research on urine source separation. We show that this is currently the only method in the Western world to have accomplished a return to circular systems of nutrition/excretion. Urine source separation can be done in multiple ways, depending on circumstances, and conditions in France are favourable to its development, despite the sociotechnical lock-in to mixed sewage management systems. In a forward-looking scenario, we therefore explore the possibility that the Paris urban area could return to, and within a few decades even surpass, the heights of circularity that it attained during the Belle Époque. In that case, alongside a socioecological transition in the other systems – water, energy, transport – the people of this territory could establish a sustainable regime for their system of nutrition/excretion. This thesis is part of the OCAPI research and action programme (www.leesu.fr/OCAPI)

Pons, Romain. "Etude sur les déterminants professionnels agricoles et leurs effets sur la reproduction et le développement de l'enfant". Thesis, Normandie, 2018. http://www.theses.fr/2018NORMC430/document.

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Les expositions professionnelles agricoles, et notamment l’exposition aux pesticides, ont été associées à divers effets négatifs, sur la fertilité, le déroulement de la grossesse et le développement de l’enfant. Peu d’études se sont intéressées à des activités agricoles spécifiques excepté le travail sous serre et la floriculture et aucune n’a été à ce jour conduite en France. (1) L’interrogation de plus de 800 femmes, incluses dans la cohorte AGRIculture & CANcer (AGRICAN) et ayant eu une grossesse depuis l’inclusion (2005), grâce à 2 questionnaires rétrospectifs a montré un allongement du délai nécessaire à concevoir en lien avec l’emploi sur une exploitation agricole, le travail de nuit ou l’exposition à des vibrations. Des augmentations de risque d’avortements spontanés et de malformations ont également été observées mais restent à confirmer. (2) Le développement d’une méthode d’analyse multi-résidus a permis de mesurer 25 pesticides différents parmi 116 recherchés dans les urines de femmes travaillant sur des exploitations de poly-culture élevage. Les herbicides étaient les plus fréquemment détectés, notamment en lien avec la présence de maïs sur l’exploitation ou de tâches réalisées au contact des animaux d’élevage. Le glyphosate ou son métabolite AMPA étaient retrouvés dans 85% des échantillons.Un projet de recherche poursuivra les travaux engagés en s’intéressant au développement cognitif des enfants nés depuis 2005
Agricultural exposures, including pesticide exposure, have been associated with several negative effects on fertility, pregnancy and child development. Few studies focused on specific agricultural activity excepted floriculture and working in greenhouse and none was conducted in France. (1) More than 800 women, enroled in the AGRIculture & CANcer (AGRICAN) cohort and who reported a pregnancy since enrolment (2005) agreed to fill in 2 questionnaires. An increase of time to pregnancy was observed for women who worked on a farm, for those exposed to night work and to vibrations. Increased risks of spontaneous abortions or abnormalities were also observed in relation to agricultural work but these results need to be confirmed. (2) Multi-residue analytical method was developed and applied to women of childbearing age, working in crop-livestock farms. Twenty-five pesticides or metabolites were detected among 116 measured in urine samples. Herbicides were the most frequently detected, especially when women worked on corn-crop farms or were involved in breeding tasks. Glyphosate or its metabolite AMPA were detected in 85% of urine samples.Future project will allow us to investigate cognitive development of children born since 2005

Roux, Aurélie. "Analyse du métabolome urinaire humain par chromatographie liquide couplée à la spectrométrie de masse à haute résolution". Paris 6, 2011. http://www.theses.fr/2011PA066575.

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L’objectif de ce travail de thèse est de développer une base de données spectrale pour faciliter l’annotation et l’interprétation biologique des jeux de données d’analyse métabolomique obtenus en utilisant la chromatographie liquide couplée à la spectrométrie de masse. Deux approches ont été utilisées : l’identification par comparaison aux spectres de masse de composés de références et l’identification directement à partir des données biologiques. Pour la première approche une chiomiothèque de métabolite a été constituée et analysée. L’identification à partir de données biologiques a été réalisée sur une cohorte de volontaires de 227 individus travaillant au CEA. 244 métabolites ont ainsi été identifiés dans les urines humaines, donc 78 jamais été décrits comme faisant parti du métabolome urinaire. 139 métabolites ont également était caractérisés sur la base de leur masse précise mais sans identification formelle. Ces 383 métabolites représentent environ 1000 ions dans chacun des modes d’ionisation. Les variations physiologiques au sein de la cohorte, en fonction de l’âge, du poids et du genre, de ces différents métabolites ont été étudiées afin de construire une base de données relationnelle. Enfin, le métabolome urinaire pouvant être affecté par les conditions de prélèvement des échantillons d’urines, nous avons réalisé des études de stabilité dans les conditions de prélèvement des métabolites précédemment caractérisés. Ces études nous ont permis de proposer des recommandations en termes de conditions de prélèvement et de stockage à court terme des urines et de mesurer l’impact de la contamination bactérienne sur les concentrations de différents métabolites urinaires

Zhao, An. "Etude des petits ARNs extracellulaires pour le diagnostic de cancer du rein à cellules claires". Phd thesis, Université Jean Monnet - Saint-Etienne, 2013. http://tel.archives-ouvertes.fr/tel-00999237.

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Le cancer du rein est un problème majeur de santé publique. Un diagnostic précoce améliore les chances de survie. Le diagnostic repose essentiellement sur les examens d'imagerie comme l'échographie, la tomodensitométrie et l'IRM. Ces examens sont parfois associés à la biopsie et sont couteux et parfois invasifs. De plus, l'imagerie n'est pas capable de faire la distinction entre les tumeurs bénignes et les tumeurs malignes et entre les sous-types histologiques de carcinome à cellules claires qui est le plus fréquent. Il n'existe pas dans le cancer rénal de marqueur comme la PSA dans le cancer de la prostate ou la Foetoprotéine et l'HCG dans le cancer du testicule. Le but de cette étude est concentré sur la recherche des marqueurs mARNs ou miARNs dans les liquides biologiques (sérum, plasma, urine) pour le cancer du rein à cellules claires. Nous avons montré que les petits ARNs dans le sérum et les urines et l'intégrité des ARNs dans les urines étaient des outils diagnostiques dans le cancer du rein à cellules claires. Si ces petits ARNs circulants sont validés, on peut éventuellement imaginer l'intérêt pratique en clinique comme la détection des petits ARNs circulants dans l'urine pour prédire le cancer, la classification de la tumeur pour aider le clinicien, la prédiction d'une récidive ou d'une progression soit après néphrectomie soit au cours d'un traitement médical

Derappe, Christian. "Étude structurale d'oligosaccharides isolées d'urine humaine de gestation : mise en évidence de l'excrétion de glycosides inconnus phosphoryles ou dérivés du myo-inositol". Paris 6, 1986. http://www.theses.fr/1986PA066325.

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Martins, Edjane Suenia Costa da Silva. "Efeito do armazenamento sobre as características de urina e águas amarelas". Universidade Estadual da Paraíba, 2016. http://tede.bc.uepb.edu.br/tede/jspui/handle/tede/2292.

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A large part of nutrients such as nitrogen, phosphorus and potassium, which are essential in agriculture, is found in human urine being their amounts, in most cases, significant, more suitable and sustainable than those in commercial fertilizers. Due to the demand for sustainable alternatives in the context of ecological sanitation, reuse of human urine can be faced as a potentially feasible alternative in the context of decentralized wastewater treatment systems. The experimental research which based this work was divided into two stages, in the first the effect of storage, within open and closed recipients, as a treatment of pure urine and yellow water, being used two containers for pure and two for a 7% dilution of urine. In order to verify the effect of storage, monitoring and evaluation were performed by means of physical, chemical and microbiological indicators. Storage of urine proved to be a cost-effective cleaning method of pure and diluted urine and. Containers with lid were more efficient in physical-chemical and biological stabilization process controlling loss of ammonia by volatilization, and contamination by the influence of the external environment. Concentrations of nutrients were maintained in high levels and fecal contamination tended to elimination in a period of 20 days, at room temperature. In the second step, the aim was the recovery of phosphorus by precipitation, carried out in a jar-test apparatus with MgO addition, at several concentrations, to pure and 7%-diluted urine to 7%. Two ranges of concentrations were used - phase A (0; 0.05; 0.15; 0.30 and 0.45 g of MgO/L) and phase B (0; 0.45; 0.60; 0.75 and 0.90 g MgO/L) - under stirring at 120 rpm, for a period of 2 hours. Precipitation and hence the phosphorus recovery was directly related to the concentration of MgO in both phases.
Grande parte dos nutrientes que são essenciais na agricultura, como nitrogênio, fósforo e potássio, é encontrada na urina humana e suas quantidades significativas são, na maioria das vezes, mais apropriadas e sustentáveis do que as encontradas nos fertilizantes químicos comerciais. Devido à demanda por alternativas sustentáveis, no contexto do esgotamento sanitário ecológico, o reuso da urina humana pode ser citado como descentralizados de tratamento de águas residuárias. A pesquisa que fundamentou este uma alternativa viável e de grande potencial na escala de sistemas trabalho foi dividida em duas etapas, tendo a primeira o objetivo de analisar o efeito de modos diversos (aberto e fechado) de armazenamento, como forma de tratamento da urina pura e de águas amarelas. Para tal foram utilizados quatro recipientes de urina pura e diluída a 7%, em dois recipientes com tampa e dois sem tampa. Para verificar o efeito do armazenamento foi realizada a caracterização, por meio de indicadores físicos, químicos e microbiológicos. O armazenamento da urina mostrou-se um método de higienização de baixo custo e bastante eficiente. Quanto às formas de armazenamento (aberta e fechada), a utilização de urina pura em recipientes com tampa mostrou-se mais eficiente no processo de estabilização físico-química e biológica, pois não ocorreu perda de amônia por volatilização, nem contaminações por influência do ambiente externo, a concentração de nutrientes foi considerada satisfatória e os níveis de coliformes termotolerantes tenderam à nulidade em um período de 20 dias, em temperatura ambiente (25 a 26ºC). Na segunda etapa, o objetivo foi a recuperação de fósforo por precipitação levada a efeito em aparelho jar-test, no qual foram adicionadas diferentes concentrações de MgO para cada 1,0 L de urina pura e de diluída a 7%. Duas faixas de concentrações foram utilizadas - fase A (0; 0,05; 0,15; 0,30 e 0,45 g de MgO/L) e fase B (0; 0,45; 0,60; 0,75 e 0,90 g de MgO/L) -, sob agitação a 120 rpm, por um período de 2 horas.A precipitação e, consequentemente a recuperação de fósforo, foi diretamente relacionada às concentrações de MgO, nas duas fases.

Più fonti

Libri sul tema "Urine humaine":

Correa, Oscar Posada. Gustavo Arcila Uribe: Armonía plástica de un pensamiento. Bogotá: Alcaldía Mayor de Bogotá, Cultura, Recreación y Deporte, Instituto Distrital de Patrimonio Cultural, 2010.

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Barnhill, Kelly Regan. The wee book of pee. Mankato, Minn: Capstone Press, 2010.

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Klosterman, Lorrie. The excretory system. Tarrytown, N.Y: Marshall Cavendish Benchmark, 2010.

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García, Camilo Borrero. Reelección, el embrujo continúa: Segundo año de gobierno de Alvaro Uribe Vélez. Bogotá, D.C., Colombia: Plataforma Colombiana de Derechos Humanos, Democracia y Desarrollo, 2004.

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Natalia, Paredes Hernández, e Plataforma Colombiana de Derechos Humanos, Democracia y Desarrollo., a cura di. El embrujo autoritario: Primer año de gobierno de Alvaro Uribe Vélez. Bogotá, D.C., Colombia: Plataforma Colombiana de Derechos Humanos, Democracia y Desarrollo, 2003.

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Amorocho, Héctor José Arenas. Contra el miedo: Conversaciones con Alirio Uribe Muñoz : la médula de la guerra sucia, derecho y justicia, acciones conjuntas y creación colectiva. Bogotá, D.C: Icono, 2018.

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Goodman, Susan E. Gee Whiz! It's all About Pee. Viking Juvenile, 2006.

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Más allá del embrujo: Tercer año de gobierno de Alvaro Uribe Vélez. Bogotá, D.C., Colombia: Plataforma Colombiana de Derechos Humanos, Democracia y Desarrollo, 2005.

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Kline, Harvey F. Fighting Monsters in the Abyss: The Second Administration of Colombian President Álvaro Uribe Vélez, 2006-2010. University Alabama Press, 2015.

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Kline, Harvey F. Fighting Monsters in the Abyss: The Second Administration of Colombian President Álvaro Uribe Vélez, 2006-2010. University of Alabama Press, 2023.

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Capitoli di libri sul tema "Urine humaine":

Qin, Weiwei, e Mingshan Wang. "Posttranslation Modifications of Human Urine". In Urine, 41–47. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-9109-5_5.

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Xiao, Xiaolian, Lili Zou e Wei Sun. "Human Urine Proteome: A Powerful Source for Clinical Research". In Urine, 9–24. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-9109-5_2.

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Gao, Youhe. "Urine Is Not a Human Waste but a Medical Treasure". In Urine, 3–8. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-9109-5_1.

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Chen, Yong. "Variations of Human Urinary Proteome". In Urine Proteomics in Kidney Disease Biomarker Discovery, 91–94. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-017-9523-4_9.

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Harada, Hidenori. "Acceptability of Urine-Diversion Dry Toilets and Resource Values of Excreta in Rural Societies". In Global Environmental Studies, 209–26. Singapore: Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-7711-3_12.

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AbstractGlobal challenges of water scarcity and food insecurity justify sanitation approaches that utilize dry sanitation with the agricultural use of excreta. One such approach is urine-diverting dry toilets (UDDTs) that separate urine and feces at the source at the time of excretion, thereby efficiently sanitizing the feces without liquid by separating the urine. However, in practice, some people have an aversion to the agricultural use of human excreta. Although the resource value of human excreta can potentially drive the spread of sanitation, this can only be achieved when a sanitation system utilizing human excreta for agriculture is accepted and rooted in society. This chapter studies the long-term acceptability of UDDTs that were installed several years ago in Vietnam, Malawi, and Bangladesh, focusing on the fertilizer value of human excreta. The majority of UDDTs were continuously used in all cases. Physical conditions and usability were the primary reasons to use UDDTs. Proportions of the continuous use of urine were low in all cases, and the perceived fertilizer values of urine by UDDT users were significantly lower than those of feces in Malawi. The fertilizer values of feces and urine alone were not always a motivation to use UDDTs although that of feces possibly contributed to the continuous use of UDDTs in Malawi. Religious impurity was a major barrier to use of urine and feces in Bangladesh, although it could be overcome with clean conditions of UDDTs and appropriate socio-cultural context.

Zou, Lili, e Wei Sun. "Human Urine Proteome: A Powerful Source for Clinical Research". In Urine Proteomics in Kidney Disease Biomarker Discovery, 31–42. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-017-9523-4_4.

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Wang, Zi, e Mingxi Li. "Evolution of the Urinary Proteome During Human Renal Development and Maturation". In Urine Proteomics in Kidney Disease Biomarker Discovery, 95–101. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-017-9523-4_10.

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Fotsis, Theodore, Michael S. Pepper, Erkan Aktas, Antonia Joussen, Friedrich Kruse, Herman Adlercreutz, Kristina Wähälä, Tapio Hase, Roberto Montesano e Lothar Schweigerer. "Inhibitors of Angiogenesis in Human Urine". In Molecular, Cellular, and Clinical Aspects of Angiogenesis, 213–27. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0389-3_20.

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Correia Sá, Luísa, Sara Sousa, Virgínia Cruz Fernandes, M. Luz Maia, Cristina Delerue-Matos e Valentina F. Domingues. "Pyrethroids Metabolites in Human Urine Samples". In Sustainable Agriculture Reviews, 227–70. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-54712-7_7.

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Sene, Moustapha, Nowaki Hijikata, Ken Ushijima e Naoyuki Funamizu. "Application of Human Urine in Agriculture". In Resource-Oriented Agro-sanitation Systems, 213–42. Tokyo: Springer Japan, 2018. http://dx.doi.org/10.1007/978-4-431-56835-3_15.

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Atti di convegni sul tema "Urine humaine":

Takaddus, Ahmed Tasnub, Prashanta Gautam e Abhilash J. Chandy. "Numerical Simulations of Peristalsis in Unobstructed Human Ureters". In ASME 2016 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/imece2016-65999.

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Urine is transported from the kidney to the urinary bladder through the ureter by peristalsis and pressure gradients. The contractile force acting on the ureter wall has drawn considerable interest in the field of biomechanics. Backflow of urine from bladder to the kidney can occur due to failure of the ureterovesical (ureteral-bladder) junction or blockage in the ureter passage because of recurrent urinary tract infection and also due to formation of stone in kidney. To understand the nature of the flow as well as its effect on the ureter wall, two-way fluid-solid interaction (FSI) modeling of the ureter peristaltic flow at different pressure is required. A transient 2D axisymmetric numerical calculation of ureteral wall peristalsis and urine flow is performed with a fully-coupled monolithic solver using an arbitrary Lagrangian-Eulerian (ALE) method. The ureter is assumed to be a circular tube with successive compression waves traveling downstream. The incompressible Navier-Stokes equations are solved to calculate the laminar flow of urine. The ureter wall is modeled as a non-linear hyper-elastic, nearly incompressible material, by curve fitting the biaxial test data of a human ureter, obtained from literature. Displacement due to peristalsis on ureteral wall is created with a compressive force having a Gaussian bell-curve variation along the length of the ureter, and a certain wavelength specified according to the data found from previous studies. It is observed that, as the compression wave travels from the abdominal part of the ureter towards to the pelvis, it is more likely for urine reflux to occur due to the failure of the ureteropelvic junction rather than the ureterovesical junction.

Matsui, Katsufumi, Kazunori Ogasawara, Emi Tamaki e Ken Iwasaki. "Urine computer interaction to avoid spattering". In the 4th Augmented Human International Conference. New York, New York, USA: ACM Press, 2013. http://dx.doi.org/10.1145/2459236.2459250.

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Silveira, A. M. V., B. Hessel e B. Blombäck. "VON WILLEBRAND FACTOR (VWF) ANTIGENS IN URINE". In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644083.

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Human urine was analyzed using a sensitive enzyme linked immunosorbent assay (ELISA) for von Willebrand factor (VWF) antigen. Urine of healthy persons contained VWF immunoreactivity. In the urine of a patient with severe von Willebrand disease, the VWF antigen was only detectable after intravenous infusion of VWF-Factor VIII concentrate. The VWF antigen in normal urine was analyzed by gel permeation high performance liquid chromatography (HPLC) and gel electrophoresis combined with immunoblotting. These analyses revealed three immunoreactive components of Mr 350 kDa, 60 kDa, and 20 kDa, respectively, the 60 kDa being the major component. Monoclonal antibodies of known specificity to VWF molecule were used in ELISA and immunoblotting to analyze urinary VWF. The three components reacted with an antibody to the central part of VWF, which is called fragment I, and contains the binding site for collagen. No significant immunoreac-tion was observed with monoclonal antibodies to the Nor C-terminal portions of VWF.VWF derivatives of molecular size similar to the largest urinary antigens were also observed in normal plasma. However, there is not an obvious relationship between these plasma forms and the products in urine since reduction of plasma and urine yields different products.These results indicate that VWF antigens excreted in normal urine are most likely fragments of VWF produced by limited degradation in vivo. This degradation preserves the central part of VWF molecule, the one which reacts with the antibody that blocks the binding of VWF to collagen.

Wang, Tsuei Lian, Hui-hua K. Chiang, Hui-hsin Lu e Yung-da Hung. "SERS quantitative urine creatinine measurement of human subject". In Biomedical Optics 2005, a cura di Tuan Vo-Dinh, Joseph R. Lakowicz e Zygmunt K. Gryczynski. SPIE, 2005. http://dx.doi.org/10.1117/12.591393.

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Santos, O. S. N., A. Kiperstok, L. M. Queiroz, M. B. Teixeira, V. P. S. Paz e A. J. P. Silva. "The Development of Bermuda Grass Irrigated with Human Urine". In II Inovagri International Meeting. Fortaleza, Ceará, Brasil: INOVAGRI/INCT-EI/INCTSal, 2014. http://dx.doi.org/10.12702/ii.inovagri.2014-a692.

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Inaba, Humio, Binkoh Yoda e Akio Saeki. "Detection of ultraweak chemiluminescence of human urine with an intensity difference for nonsmokers and smokers". In OSA Annual Meeting. Washington, D.C.: Optica Publishing Group, 1986. http://dx.doi.org/10.1364/oam.1986.wg48.

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This paper reports for the first known time the measurement of ultraweak spontaneous chemiluminescence, generated without any external excitation, from human urine samples similar to blood.1,2 with an ultrahigh-sensitivity photon-counting system that was developed recently using a selected photomultiplier operated in optimum conditions.

Santos, O. S. N., A. Kiperstok, L. M. Queiroz, M. B. Teixeira, H. R. Gheyi e C. S. Linge. "Irrigation of Bermuda Grass with Human Urine: Use of Micronutrients". In II Inovagri International Meeting. Fortaleza, Ceará, Brasil: INOVAGRI/INCT-EI/INCTSal, 2014. http://dx.doi.org/10.12702/ii.inovagri.2014-a691.

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Kalampokis, Evangelos, Theodora Nikou, Dimitrios Michailidis, Christina Fytili, Nikolaos Tentolouris e Maria Halabalaki. "Isolation and identification of urine metabolites after hydroxytyrosol supplementation in humans". In GA – 69th Annual Meeting 2021, Virtual conference. Georg Thieme Verlag, 2021. http://dx.doi.org/10.1055/s-0041-1736850.

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de Vries, J. X., R. Raedsch, A. Stiehl, U. Voelker, I. Walter-Sack e E. Weber. "EVIDENCE FOR BIIIARY EXCRETION OF PHENPROCOUMON AND ITS METABOLITES IN HUMANS; IDENTIFICATION BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY AND GAS CHROMATOGRAPHY-MASS SPECTROMETRY". In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643272.

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Recently it has been shown that in man the oral couma-rin anticoagulant phenprocoumon is eliminated up to 60-70 % in urine and 30-40 % in faeces; in urine phenprocoumon (PH) and its metabolites 7-hydroxy-(7-OH),6-hydroxy-(6-OH) and 4'-hydroxy-(4'-OH) phenprocoumon are present mainly as conjugates. No data so far were available on the biliary excretion of these compounds.We examined bile obtained from four in-patients during PH treatment; bile samples were aspirated in the duodenum at the papilla during routine diagnostic endoscopy and immediately deep frozen before analysis. Samples were extracted both untreated as well as after hydrolysis with 6-glucuronidase/aryl sulfatase and separated by reversed phase gradient elution high performance liquid chromatography (HPLC) with fluorescence detection; for confirmation, the same extracts were methylated and analysed by gas chromatography-mass spectrometry (CG-MS) (J.X.de Vries et al J Chromatogr., 338 (1985) 325). PH, 7-OH, 6-OH and 4'-OH were identified by comparison with synthetic authentic samples'''''''

Kuzmina, L. P., E. S. Tsidilkovskaya e A. G. Khotuleva. "CHANGES IN SCREENING MARKERS OF THE IMMUNE STATUS OF WORKERS AT A LEAD RECYCLING PLANT". In The 17th «OCCUPATION and HEALTH» Russian National Congress with International Participation (OHRNC-2023). FSBSI «IRIOH», 2023. http://dx.doi.org/10.31089/978-5-6042929-1-4-2023-1-269-272.

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The problem of the adverse effect of lead on human health currently remains relevant, especially in occupational medicine. One of the targets of the toxic effect of lead is the immune system, which determines the relevance of research aimed at assessing the immune status of workers in contact with lead and its compounds. The purpose of this study was to evaluate changes in the screening markers of the immune status (leukocyte parameters, immunoglobulins of classes A, M, G) in workers of a lead recycling plant. Materials and methods. The main group — 49 employees of the plant for the recycling of lead-containing products with a length of service of 7 (3; 9) years, the control group — 23 men working without contact with harmful occupational factors. A laboratory examination was carried out, including the study of the blood lead level, ALA in the urine, leukocyte counts and immunoglobulins of classes A, M, G. Results. An inverse correlation was found between the level of IgA in workers of a lead recycling plant with length of service (r=–0.393, p=0.005) in the absence of age dependence, with the blood lead level (r=-0.313, p=0.027). Also, the dependence of the levels of immunoglobulins of classes A, M, G on the concentration of ALA in the urine was revealed: at the level of ALA in the urine ≥20 μmol/gCR, the levels of immunoglobulins are significantly lower than at ALA <20 μmol/gCR. Conclusion. The revealed trend towards a decrease in humoral immunity with higher ALA values in the urine, a decrease in IgA with an increase in length of service indicate the effect of lead and its compounds on the state of humoral immunity and determine the significance of studying changes in IgA, IgM and IgG in dynamics in workers of a lead recycling plant for optimization of preventive measures.

Rapporti di organizzazioni sul tema "Urine humaine":

Green, Ashley. Certification of Standard Reference Material® 3666 Albumin and Creatinine in Frozen Human Urine. Gaithersburg, MD: National Institute of Standards and Technology, 2023. http://dx.doi.org/10.6028/nist.sp.260-238.

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Wrenn, M. E., N. P. Singh e Ying-Hua Xue. Plutonium in human urine: Normal levels in the US public. 1991 Annual report, Volume 2. Office of Scientific and Technical Information (OSTI), marzo 1997. http://dx.doi.org/10.2172/451237.

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Kanner, Joseph, Edwin Frankel, Stella Harel e Bruce German. Grapes, Wines and By-products as Potential Sources of Antioxidants. United States Department of Agriculture, gennaio 1995. http://dx.doi.org/10.32747/1995.7568767.bard.

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Several grape varieties and red wines were found to contain large concentration of phenolic compounds which work as antioxidant in-vitro and in-vivo. Wastes from wine production contain antioxidants in large amounts, between 2-6% on dry material basis. Red wines but also white wines were found to prevent lipid peroxidation of turkey muscle tissues stored at 5oC. The antioxidant reaction of flavonoids found in red wines against lipid peroxidation were found to depend on the structure of the molecule. Red wine flavonoids containing an orthodihydroxy structure around the B ring were found highly active against LDL and membrane lipid peroxidation. The antioxidant activity of red wine polyphenols were also found to be dependent on the catalyzer used. In the presence of H2O2-activated myoglobin, the inhibition efficiency was malvidin 3-glucoside>catechin>malvidin>resveratol. However, in the presence of an iron redox cycle catalyzer, the order of effectiveness was resveratol>malvidin 3-glucoside = malvidin>catechin. Differences in protein binding were found to affect antioxidant activity in inhibiting LDL oxidation. A model protein such as BSA, was investigated on the antioxidant activity of phenolic compounds, grape extracts, and red wines in a lecithin-liposome model system. Ferulic acid followed by malvidin and rutin were the most efficient in inhibiting both lipid and protein oxidation. Catechin, a flavonal found in red-wines in relatively high concentration was found to inhibit myoglobin catalyzed linoleate membrane lipid peroxidation at a relatively very low concentration. This effect was studied by the determination of the by-products generated from linoleate during oxidation. The study showed that hydroperoxides are catalytically broken down, not to an alcohol but most probably to a non-radical adduct. The ability of wine-phenolics to reduce iron and from complexes with metals were also demonstrated. Low concentration of wine phenolics were found to inhibit lipoxygenase type II activity. An attempt to understand the bioavailability in humans of antocyanins from red wine showed that two antocyanins from red wine were found unchanged in human urine. Other antocyanins seems to undergo molecular modification. In hypercholesterolemic hamsters, aortic lipid deposition was significantly less in animals fed diets supplemented with either catechin or vitamin E. The rate of LDL accumulation in the carotid arteries was also significantly lower in the catechin and vitamin E animal groups. These results suggested a novel mechanism by which wine phenolics are associated with decreased risk of coronary heart diseases. This study proves in part our hypothesis that the "French Paradox" could be explained by the action of the antioxidant effects of phenolic compounds found at high concentration in red wines. The results of this study argue that it is in the interest of public health to increase the consumption of dietary plant falvonoids. Our results and these from others, show that the consumption of red wine or plant derived polyphenolics can change the antioxidant tone of animal and human plasma and its isolated components towards oxidative reactions. However, we need more research to better understand bioavailability and the mechanism of how polyphenolics affect health and disease.

Fourth national report on human exposure to environmental chemicals. National Center for Environmental Health, marzo 2021. http://dx.doi.org/10.15620/cdc:105345.

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Abstract (sommario):

"The Updated Tables, March 2021) presents nationally representative, cumulative biomonitoring data gathered from 1999–2000 through 2015–2016. It includes all the data from each of the previous National Reports on Human Exposure to Environmental Chemicals and each of the previous Updated Tables (collectively, the Report and Updated Tables). In each survey period, the reported chemicals or their metabolites were measured in blood, serum, and urine samples from random subsamples of the National Health and Nutrition Examination Survey (NHANES). These subsamples typically consisted of about 2,500 participants – exact numbers are included in the tables. Survey data and samples are collected by the Centers for Disease Control and Prevention (CDC) National Center for Health Statistics. CDC’s Environmental Health Laboratory (Division of Laboratory Sciences (DLS), National Center for Environmental Health) used mass spectrometry methods to obtain the blood, serum, and urine exposure measurements presented in the Report and Updated Tables. Volume One (1999-2010) and Volume Two (2011-2016) contain data tables for chemicals measured in the general U.S. population Volume Two: NHANES 2011-2016 provides data on the general U.S. population from NHANES 2011-2012, 2013–2014, and 2015-2016. CS272983-A FourthReport_UpdatedTables_Volume2_Mar2021-508.pdf"

Fourth national report on human exposure to environmental chemicals. Updated tables, March 2021 : volume two: NHANES 2011-2016. National Center for Environmental Health (U.S.), marzo 2021. http://dx.doi.org/10.15620/105345.

Testo completo

Gli stili APA, Harvard, Vancouver, ISO e altri

Abstract (sommario):

"The Fourth National Report on Human Exposure to Environmental Chemicals: Updated Tables, March 2021 (the Updated Tables, March 2021) presents nationally representative, cumulative biomonitoring data gathered from 1999–2000 through 2015–2016. It includes all the data from each of the previous National Reports on Human Exposure to Environmental Chemicals and each of the previous Updated Tables (collectively, the Report and Updated Tables). In each survey period, the reported chemicals or their metabolites were measured in blood, serum, and urine samples from random subsamples of the National Health and Nutrition Examination Survey (NHANES). These subsamples typically consisted of about 2,500 participants – exact numbers are included in the tables. Survey data and samples are collected by the Centers for Disease Control and Prevention (CDC) National Center for Health Statistics. CDC’s Environmental Health Laboratory (Division of Laboratory Sciences (DLS), National Center for Environmental Health) used mass spectrometry methods to obtain the blood, serum, and urine exposure measurements presented in the Report and Updated Tables. Volume One (1999-2010) and Volume Two (2011-2016) contain data tables for chemicals measured in the general U.S. population Volume Two: NHANES 2011-2016 provides data on the general U.S. population from NHANES 2011-2012, 2013–2014, and 2015-2016. CS272983-A FourthReport_UpdatedTables_Volume2_Mar2021-508.pdf"