Tesi sul tema "Système nerveux – Chez l'enfant"
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Kazemi, Kamran. "L' intégration d'information bas et haut-niveau pour la segmentation optimisée d'images cérébrales 3D chez l'enfant nouveau-né". Amiens, 2008. http://www.theses.fr/2008AMIED004.
Testo completoIn this thesis, as the first step, we created a neonatal brain probabilistic atlas consisting of atlas template and probabilistic models for brain, cerebrospinal fluid (CSF) and skull. The atlas is created based on high resolution T1 Magnetic Resonance images of 7 individuals with gestational ages between 39 and 42 weeks at date of examination. The atlas template was evaluated by i) determining the deviation of characteristic anatomical landmarks and ii) the total amount of local deformation needed for the different brain tissues to meet the normalized neonatal image. In the second part of the thesis, we constructed a neonatal cerebral MR image simulator based on our created 3D digital neonatal neurocranial phantom. The created neonatal brain phantom consists of 9 different tissue types: scalp, skull, fat, muscle, dura mater, gray matter, myelinated white matter, non-myelinated white matter and CSF. The digital phantom was used to map simulated nuclear magnetic resonance signal intensities to simulate MR images of the newborns' head. The simulated images with controlled degradation of image data may serve as an evaluation data set for evaluating neonatal MRI analysis methods, e. G. Segmentation/registration algorithms. In the last part of this thesis, we developed an automatic tissue segmentation method for newborn brains from magnetic resonance images. We applied an atlas based algorithm for brain, CSF and skull segmentation of the newborns from 3D T1 weighted MR images. We used the segmentation method based on EM algorithm and Markov random filed which is implemented in SPM toolbox and its VBM toolbox in conjunction with our created probabilistic atlas as prior information. The results demonstrate that our method realizes a tool capable to segment reliably brain, CSF and skull from MRI of neonates
FILIPECKI, JEAN-MARC. "Neurocysticercose chez l'enfant : a propos de 2 observations ; revue de la litterature". Nice, 1989. http://www.theses.fr/1989NICE6565.
Testo completoJOLY, HELENE. "Maturation postnatale des voies motrices centrales chez l'enfant : etude electrophysiologique et applications". Amiens, 1991. http://www.theses.fr/1991AMIEM054.
Testo completoKhater-Boidin, Josette. "Recherches sur le developpement du systeme nerveux chez le premature, le nouveau-ne a terme et l'enfant (donnees histologiques et electrophysiologiques)". Paris 6, 1988. http://www.theses.fr/1988PA066328.
Testo completoMikaeloff, Yann. "Atteintes démyélinisantes aigües inflammatoies du système nerveux central chez l'enfant : facteurs pronostiques d'évolution vers la sclérose en plaques et le handicap". Lyon 1, 2004. http://www.theses.fr/2004LYO10053.
Testo completoBrissaud, Olivier. "Etude de 2 observations de scléroses en plaques chez l'enfant. Pathogénie, aspect thérapeutique actuels et revue de la littérature". Bordeaux 2, 1999. http://www.theses.fr/1999BOR23074.
Testo completoLAQBAQBI, ALAMI FATIMA-ZOHRA. "Les maladies demyelinisantes du systeme nerveux central : physiopathologie et traitements a propos de 3 cas de myelite aigue transverse chez l'enfant". Reims, 1990. http://www.theses.fr/1990REIMM117.
Testo completoKhater-Boidin, Josette. "Recherches sur le développement du système nerveux chez le prématuré, le nouveau-né à terme et l'enfant données histologiques et électrophysiologiques /". Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb376146575.
Testo completoAarabi, Ardalan. "Détection et classification spatiotemporelle automatique d'évènements EEG pour l'analyse de sources d'activité cérébrale chez le nouveau-né et l'enfant". Amiens, 2007. http://www.theses.fr/2007AMIED002.
Testo completoNeonates, especially the premature ones, are at high risk of brain damage and life-long cognitive disability. Concerning the full-term neonates, neurological pathologies are often accompanied by epileptic manifestations. These newborns may be impaired in other domains including coordination, cognition and behavior. EEG is a useful non-invasive tool to measure the electrical activity of the brain. In this thesis, we developed tools to identify normal and pathological EEG events in neonates and children. We paid a special attention to detect (i) seizures by using specific age-dependant features of the newborn EEG, (ii) brain epileptic states and (iii) short-term events like spikes and spike-and-waves for each state. We characterized EEG events by extracting a set of contextual features in order to classify them. Then, the location of cerebral generators was found and tracked by spatial clustering of the equivalent dipoles of the EEG events in different brain states. The results showed good sensitivities and selectivities with a low false detection rates in neonates and children
Pruvost, Mickael. "Crises Convulsives et Système Nerveux Autonome - Analyse de la Coordination Cardiorespiratoire par des Méthodes Spectrale, Géométrique et Symbolique". Phd thesis, Université de Picardie Jules Verne, 2007. http://tel.archives-ouvertes.fr/tel-00275235.
Testo completoDans cette étude, nous avons mis en relation une méthode d'analyse géométrique du rythme cardiaque avec cette méthode spectrale et également développé une autre méthode, basée sur un codage symbolique de la variabilité cardiorespiratoire. Cette dernière méthode, liée à une estimation du taux d'entropie pour la détermination de la longueur du modèle à employer pour l'étude d'un sujet, donne une valeur de la coordination entre les rythmes cardiaques et respiratoires.
Appliquées chez des adolescents épileptiques traités par stimulation vagale, ces trois méthodes ont montré des modifications des activités du système nerveux autonome. De plus, dans cette partie, nous avons pu démontrer la non fiabilité des résultats issues de la méthode spectrale chez des sujets jeunes en conservant les paramètres d'origines. Les méthodes géométrique et symbolique ont enfin été exploitées pour l'étude d'adultes et de nouveaux nés présentant des crises. Les paramètres d'enregistrements ne permettant pas d'obtenir des résultats précis sur l'analyse du système nerveux chez l'enfant, des propositions pour les améliorer ont été faites et de futures conclusions potentiellement intéressantes concernant la compréhension du développement des crises sont attendues.
Constant, Isabelle. "Exploration non invasive du systeme nerveux autonome a destinee cardio-vasculaire chez l'enfant : consequences de la suppression de la variabilite de frequence cardiaque". Paris 7, 1999. http://www.theses.fr/1999PA077057.
Testo completoSallaberry-Watteau, Marion. "Troubles neurologiques congénitaux et roaccutane : à partir de deux observations". Bordeaux 2, 1999. http://www.theses.fr/1999BOR2M107.
Testo completoCasagranda, Léonie. "Évaluation de l’impact d’une consultation médicale de suivi à long terme sur l’état de santé de jeunes adultes guéris d’un cancer pédiatrique (hors leucémie)". Thesis, Saint-Etienne, 2015. http://www.theses.fr/2015STET003T/document.
Testo completoIntroduction - What is the model of long-term follow-up adapted to the expectations and needs of youngadults cured of a childhood cancer? Method – The aim of this study was to estimate the impact of a long-term follow-up care (LTFU) associated self-questionnaire and medical consultation, on the health of young adult survivors of childhood cancer. Young adults with childhood cancer between 1987 and 1992 in Rhône-Alpes-Auvergne were seen during a LTFU medical and psychological consultation (SALTO), which was preceded and followed by a self-questionnaire. Furthermore, the capacity of adaptation of their autonomous nervous system (ANS) was estimated to determine the characteristics of the subjects whose ANS was altered. Results - 207 young adults completed a questionnaire before consultation and 197 of them declared having sequalae, on average each self-reported 3.4 late effects, which was confirmed by a medical observation made at 150 consultations (mean 2.6 observed late effects/subject). After the consultation, about 70 % of the subjects modified their number of self-reported late effects. No particular characteristic was clearly highlighted in people with an altered capacity of ANS regulation but a significant relationship was established between altered ANS and cardiovascular complication (P=0,049). A satisfaction survey showed a very favorable opinion about the SALTO consultation. Approximately 80% of the subjects presenting a psychiatric disorder at the time of the consultation had received no psychological follow-up at this time. Conclusion - Long-term follow-up of young adult survivors of a childhood cancer is necessary, feasible and answers a real need
Bouzas, Rodriguez Jimena. "The neurotrophin receptor TrkC, a new dependence receptor involved in the control of neuroblastoma tumorigenesis". Thesis, Lyon 1, 2010. http://www.theses.fr/2010LYO10059.
Testo completoThe tyrosine kinase receptor TrkC is a neurotrophin receptor that assures an adequate establishment of proprioceptive neurons during nervous system development. Upon neurotrophin‐3 (NT‐3) binding TrkC transduces a classic survival signal, while in absence of trophic support a program of apoptotic cell death will take place. However the molecular mechanisms leading to neuron cell death are not understood. On the other hand, although TrkC was first identified as an oncogene, it may also accomplish a proapoptotic role in cancer. Indeed its expression has been correlated with a good prognosis of Neuroblastoma, the most common extracranial solid tumor of early childhood. Thisapparent paradox could be explained by the dependence receptor notion: these receptors induce apoptotic cell death in settings of absence of ligand, whereas the presence of their ligand inhibits this proapoptotic activity. We provide evidence here that among neurotrophin receptors, only TrkC is a dependence receptor and its activity relies on the caspase‐mediated cleavage of its intracellular domain, which allows the release of a proapoptotic fragment. Moreover, we show that an autocrine production of NT‐3 concerns a large fraction of aggressive neuroblastoma and provides a selective advantage by allowing malignant cells to overcome with TrkC antitumoral control. We demonstrate that the disruption of the TrkC/NT‐3 interaction triggers neuroblastoma cell death in vitro andprevents tumor growth and metastasis in avian and murine models. This work set the basis for analternative anticancer therapeutic strategy relying on the reengagement of a cell death program mediated by unbound TrkC
Roche-Labarbe, Nadège. "Couplage de l'EEG et de la spectroscopie dans le proche infrarouge (NIRS) pour l'étude de la fonction et de la maturation cérébrale chez le nouveau-né, en particulier prématuré". Amiens, 2007. http://www.theses.fr/2007AMIED004.
Testo completoNeonates, especially premature ones, are fragile and should not be moved. Current techniques for their routine neurological follow-up are usable at the child's bedside but do not cover all the aspects of brain function. It is thus necessary to develop complementary techniques, usable at the child's bedside and non-invasive, to study haemodynamic aspects (like NIRS), and to improve current techniques (like EEG). In this work, we gave evidence that EEG source localisation is feasible in premature neonates, and gave a first evaluation of the influence of the main skull parameters (thickness, conductivity, fontanels) on the location variation range. Simultaneous recording of EEG and NIRS in premature neonates, infants, children and a rat model of epilepsy allowed us to evaluate the relevance of this approach to study physiological and pathological activities. Various information of biological and clinical interest have been extracted from these studies. This whole work highlighted the advantage of NIRS temporal resolution and ease of use compared with other techniques for haemodynamic functional explorations. These results allowed us to propose leads to develop the use of EEG and NIRS in neonates, that should improve their follow-up and help to reduce the consequences of premature birth
Ghysen, Alain. "Le développement du système nerveux chez la drosophile". Doctoral thesis, Universite Libre de Bruxelles, 1991. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/213073.
Testo completoClerici, Christine. "Système nerveux autonome et bronchomotricité chez le cobaye". Paris 12, 1990. http://www.theses.fr/1990PA120028.
Testo completoChastang, Julie. "Troubles du neurodéveloppement de l’enfant : vécu des parents et des enseignants, qualité de vie et outil de repérage". Electronic Thesis or Diss., Sorbonne université, 2023. http://www.theses.fr/2023SORUS598.
Testo completoIn France, neurodevelopmental disorders (NDD) affect 10 to 15% of children. Early detection of NDD is of crucial importance due to the maximum brain plasticity in the first 3 years of a child's life. Early detection should allow children to access early interventions that optimize their neurodevelopmental trajectory. This thesis initially focused on the experiences of parents of children with NDD and their quality of life. Parents described a complex journey, marked by waiting times for diagnosis which had significant repercussions on their quality of life, difficulties in accessing care, as well as a challenging journey facing the challenges related to their child(ren)'s schooling. Being supported by their primary care physician seemed to enhance their quality of life, while the delay to diagnosis negatively impacted it. Complementarily, this thesis also studied the experiences of teachers. It emerged that many of the difficulties identified by parents are shared by teachers. Both parents and teachers reported feelings of abandonment and loneliness in addressing the children's needs. They shared observations about the difficulties in identifying disorders, delays in diagnosis, complicated pathways, and a lack of support and resources. A recurring theme was the lack of coordination between parents, teachers, and the healthcare sector. Given the finding that no readily accessible tool existed for frontline use to identify deviations from the expected neurodevelopmental trajectory, a multidisciplinary group of experts was convened under the auspices of the inter-ministerial delegation to the national strategy for autism and neurodevelopmental disorders. This working group developed a detection grid based on existing literature and pre-existing tools, and this grid has been usable since 2019. The purpose of this thesis was to evaluate, for the first time, the use of this detection grid in the general population in primary care. The results obtained align with existing literature regarding the expected prevalence of NDD at the tested ages and factors associated with early identification of deviations in the neurodevelopmental trajectory. In summary, this thesis sought to explore the experiences of parents and teachers and the challenges they face, highlighting the complexities in the life journey of children with NDD and their families. From these observations, it aimed to find a solution for early detection of NDD by introducing, for the first time in primary care, a tool for detecting NDD
Baratte, Blandine. "Caractérisation chez une annélide polychète (nereis diversicolor o. F. Muller) de peptides apparentés au fmrf-amide : localisation immunocytochimique purification-structure". Lille 1, 1990. http://www.theses.fr/1990LIL10092.
Testo completoRobert, Lawrence. "Système informatique d'évaluation de la fonction cardiaque chez l'enfant". Compiègne, 1996. http://www.theses.fr/1996COMP932S.
Testo completoBranchi, Igor. "La souris de laboratoire : modèle d'étude chez l'animal des risques neurotoxiques et des maladies neurodégénératives chez l'humain". Orléans, 2001. http://www.theses.fr/2001ORLE2011.
Testo completoArtaud, Marie-Sylvie. "Atteintes du système nerveux central chez l'adulte au cours du sida". Bordeaux 2, 1988. http://www.theses.fr/1988BOR25265.
Testo completoDufour, Heloïse. "Evolution du système nerveux des chordés : étude chez l’urochordé Ciona intestinalis". Paris 6, 2007. http://www.theses.fr/2007PA066425.
Testo completoThe visceral nervous system (VNS) controls our digestive, respiratory and cardio-vascular functions. The homeodomain transcription factor Phox2b is specifically expressed in the neurones that compose it and controls their differentiation. This extreme specificity makes Phox2b a powerful tool to investigate the VNS phylogenetic history. I focused on the urochordate Ciona intestinalis whose adult lives attached to a rock and filters water to breathe and feed. I hypothesized that, in the absence of any locomotion, their nervous system should be almost entirely visceral. It showed that indeed, the vast majority of the neurons of the adult cerebral ganglion expresses a molecular code (Phox2+, Tbx20+, ChAT+, Mnr2-) specific for vertebrates branchial and visceral motoneurons. I also showed that these neurons innervate muscles that are used to contract the branchial basket composing the greatest part of the animal. The homology between these neurons and vertebrates branchial motoneurons is further supported by their developmental origin. Indeed, I showed that the adult ganglion derives from the embryonic neck region and that this region expresses Phox2 and Hox1, and is thus homologous to the vertebrate hindbrain, where branchial motoneurons differentiate. This reassignement of the ascidian larval neck to a hindbrain status, as opposed to an isthmic region as previously accepted, led me to substantially revise the chordate tripartite brain model. These data show that the ascidian neck region, homologous to the vertebrate hindbrain, gives rise just like the latter to branchial motoneurons and pushes back the evolutionary origin of cranial nerves to before the emergence of craniates
Legrand, Agathe. "Interférences entre le système oculomoteur et le système postural chez l'enfant et l'adulte". Thesis, Paris 5, 2013. http://www.theses.fr/2013PA05H130.
Testo completoThe postural system is a sensory motor complex controlled which permit two high functions, the stabilization and the orientation of body. The postural control is permit by the integration of three sensorial inputs, vestibular, somatosensory and visuals by the central nervous system; it carries adaptative transformations and coordinates this information to generate the appropriate muscles responses. For a long time, the posture has been considered like as an automatic system, but recents studies showed the regulation by attentionals processes. Further studies used the dual-task paradigm in adults and more recently in children, to understand interferences between a cognitive task and a postural task. The interactions depend on various factors such as the difficulty of the cognitive task, the difficulty of the postural task, the environmental context, the attentional capacity and the age. Choose oculomotor task as task associated at postural task allows simple, varying the protocol used to observe the behavior of adults and children in tasks involving different attentionals levels and different brain regions. Several experimental oculomotors paradigms allow to stimulate different types of saccades. The objective of this thesis is to understand, by using the dual-task paradigm, the interactions between the oculomotor system and the postural system in children. Initially, we observed these interferences in young adults then we compared the adults postural and oculomotor performance to those of children aged 7 to 12 years. Three oculomotor tasks, fixation, reactive saccades and antisaccades, were recorded simultaneously to two postural tasks, standard Romberg and tandem Romberg. Children aged 7-8 years achieve on oculomotor performance the reactive saccade task like adults, by cons their postural parameters are higher than adults. When we increase the difficulty of the oculomotor task, in case in antisaccade task, leads very quickly at the decrease of the oculomotor and postural performances for children aged 7 to 12 years. Generally, results show that the oculomotor difficulty leads to modifications of postural parameters and the postural difficulty do not seem modify the oculomotor parameters. These interferences can be associated with a large number of common brain structures activated for both tasks
Ferraz, Teixeira de Barros Karla Mônica. "Dénutrition natale : Aspects structuraux et biomécaniques du développement de l'activité locomotrice chez le rat". Compiègne, 2006. http://www.theses.fr/2006COMP1657.
Testo completoParent, Martin. "La collatéralisation axonale dans les ganglions de la base chez le primate". Thesis, Université Laval, 2006. http://www.theses.ulaval.ca/2006/23629/23629.pdf.
Testo completoDegoute, Christian-Serge. "Contrôle de la microcirculation cochléaire par le système nerveux autonome chez l'homme". Lyon 1, 1997. http://www.theses.fr/1997LYO1T020.
Testo completoVergote, David. "Immunité innée et système nerveux : étude protéomique chez la sangsue Hirudo medicinalis". Lille 1, 2004. https://pepite-depot.univ-lille.fr/RESTREINT/Th_Num/2004/50376-2004-55.pdf.
Testo completoDadure, Christophe. "Intérêt clinique et effets adverses liés aux blocs nerveux périphériques continus chez l'enfant". Montpellier 1, 2009. http://www.theses.fr/2009MON1T028.
Testo completoRecently, continuous peripheral nerve blocks (CPNB) have generated increasing interest in children. They are mainly used for postoperative pain with middle or long duration. The interest of CPNB was shown in postoperative acute pain, to prevent the development of chronic pain symptoms, and in the treatment of recurrent chronic pain. Compared to epidural analgesia, CPNB allow to decrease significantly postoperative side effects with the same quality of analgesia. The second part of this work was based on evaluation of complications and side effects with CPNB. 339 catheters was evaluated in 292 children for 5 years. There was no complications and 211 minor side effects was noted in 153 catheters. The most frequent adverse events were mechanical problems due to catheter, and nausea and vomiting following. Controversially to adults, infectious complications were rare in children. The last part of this work was centered on muscle toxicity of local anesthetic in young animal, with mitochondrial and ultrastructural damages. The myotoxicity due to continuous peripheral nerve infusion of bupivacaine demonstrated more severe alerations in young rats compared to adult ones. Damages were focused on mitochondria with alterations of cellular respiratory chain, reduction of mitochondrial adenosine triphosphate synthesis rate and citrate synthesis activity, and muscle ultrastructural damages
Desprat, Corinne. "Le système neuropeptide FF chez la souris : biochimie et pharmacologie". Toulouse 3, 1997. http://www.theses.fr/1997TOU30056.
Testo completoGaudinière, Valence Dorothée. "La Réactivité émotionnelle chez la caille : approches comportementales, cardiaque et génétique". Tours, 2006. http://www.theses.fr/2006TOUR4029.
Testo completoThe aim was to study the influence of the emotional reactivity on behavioural and cardiac responses in birds during emotional situations. Behavioural and heart rate variability measurements were studied in quail selected on either a long (LTI) or a short (STI) tonic immobility duration. STI and LTI quail exhibit low and high emotional reactivity. In 2 emotional situations, sympathetic activity increased in all lines, however, parasympathetic activity decreased in STI and LTI during an object presentation while it increased in STI after an acoustic stimulation. Emotional reactivity and the test situation then influence autonomic and behavioural responses during emotional situation. Finally, the study of the emotional responses could help the evaluation of animal welfare in rearing conditions
Lambás-Señas, Laura. "Les neurones adrénergiques centraux : caractérisation anatomo-biochimique et pharmacologique chez le rat". Lyon 1, 1986. http://www.theses.fr/1986LYO1W244.
Testo completoBouhouche, Ahmed. "Etude des mutants neurologiques minibrain [exposant] 3 et no-bridge [exposant] KS49 : exemples de relations entre gènes, anomalies nerveuses, comportement et apprentissage chez Drosophila melanogaster". Toulouse 3, 1992. http://www.theses.fr/1992TOU30146.
Testo completoVinay, Laurent. "La boucle spino-rubro-spinale chez le chat : importance des mécanismes de rétroaction dans le contrôle moteur". Aix-Marseille 1, 1990. http://www.theses.fr/1990AIX11304.
Testo completoFichard, Agnès. "Analyse in vitro de l'innervation épidermique chez l'embryon d'oiseau : caractérisation d'un facteur chimiotactique négatif impliqué dans la réaction d'évitement de l'épiderme par les fibres nerveuses". Grenoble 1, 1989. http://www.theses.fr/1989GRE10137.
Testo completoBruno, Aurélie. "Caractérisation moléculaire des lymphomes primitifs du système nerveux central chez le sujet immunocompétent". Thesis, Université Paris-Saclay (ComUE), 2015. http://www.theses.fr/2015SACLS085.
Testo completoPCNSL represent a rare extranodal diffuse large B cell lymphoma (DLBCL) with a post-GC phenotype whose tumorigenesis is still poorly unknown.Our objective was to characterize the molecular genetic alterations of PCNSL using high throughput technologies.Results: We demonstrated 1/ a high incidence of somatic mutations in genes involved in the BCR/TLR/NF-κB pathway, especially MYD88, CD79B and TBL1XR1; 2/ recurrent chromosome imbalances such as 6q22 loss and 6q (HLA locus) homozygous deletions; 3/ TERT promoter mutations and 4/ gene fusions such as ETV6-IGH. Several alterations are associated with a prognostic impact (6q22 loss and CDKN2A homozygous deletions) or are promising targets for novel therapies.To conclude, PCNSL and extracerebral DLBCL share many similarities in terms of molecular genetic profile despite some specificities. PCNSL may result from a specific tumorigenesis but also from its peculiar microenvironment
Kerner, Pierre. "Etude de l'évolution du système nerveux chez les animaux : neurogenèse comparative et phylogénomique". Paris 11, 2009. http://www.theses.fr/2009PA112011.
Testo completoStudies of the evolution of the nervous system of animals consist mainly of morpho-anatomic comparisons of this structure between different species and comparisons of developmental and genetic processes governing its formation. Bilaterians, animals displaying bilateral symmetry, are characterized by the presence of a central and peripheral nervous system, which raises the question of its origin during evolution. Among the three bilaterian lineages, the Deuterostomes, the Ecdysozoans and the Lophotrochozoans, studies that aimed to answer this question were carried almost exclusively on vertebrates (Deuterostomes) and drosophila (Ecdysozoans). This thesis presents complementary data from a Lophotrochozoan organism, the annelid Platynereis dumerilii. These data yield crucial information to determine which aspects of neurogenesis are ancestral to Bilaterians, and which are derived characteristics specific of one or the other lineage. Using a candidate-gene approach, several similarities between vertebrates and Platynereis neurogenesis were identified, suggesting a conservation of an ancestral organization of the central and peripheral nervous system of these organisms. These results also suggest a novel hypothesis concerning the origin of the vertebrates neural tube. The candidate-gene approach was completed by phylogenomic studies that allowed to elucidate several gene families evolutionary histories, and to illustrate some genomic events such as gene duplications or gene complex formation
Astier, Lorent Bernadette. "Les neurones adrénergiques centraux : études immunohistochimique et biochimique chez le rat". Lyon 1, 1988. http://www.theses.fr/1988LYO1W257.
Testo completoBorderie, Didier. "Conception et implémentation d'un système de simulation du processus de catégorisation chez l'enfant : le système ROCE". Aix-Marseille 3, 1997. http://www.theses.fr/1997AIX30083.
Testo completoDjeddi, Djamal-Dine. "Etude des interactions entre le reflux gastrooesophagien, le système nerveux autonome et le sommeil chez le nouveau-né". Amiens, 2011. http://www.theses.fr/2011AMIED001.
Testo completoElipot, Yannick. "Evolution du système nerveux et du comportement chez le poisson cavernicole aveugle Astyanax mexicanus". Phd thesis, Université Paris Sud - Paris XI, 2013. http://tel.archives-ouvertes.fr/tel-00978774.
Testo completoGaudreault, Valérie. "L'hypertension d'effort chez les patients avec syndrome métabolique : le rôle du système nerveux autonome". Thesis, Université Laval, 2007. http://www.theses.ulaval.ca/2007/24344/24344.pdf.
Testo completoRichalet, Jean-Paul. "Rôle du système nerveux autonome dans les adaptations cardiovasculaires en hypoxie d'altitude chez l'homme". Paris 11, 1989. http://www.theses.fr/1989PA112216.
Testo completoTiadi, Bi Kuyami Guy-Aimé. "Mouvements oculaires chez l'enfant dyslexique". Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLS588/document.
Testo completoABSTRACTDevelopmental dyslexia is a neurodevelopmental disorder that affects written language learning of about 10% of school-age children. During the last years, several studies have shown the presence of oculomotor abnormalities in dyslexia. However, several questions about the oculomotor performance of dyslexic children are still unanswered.We conducted three studies to examine eye movements of dyslexic children with respect to non-dyslexic age-matched children. In the first of our study, we investigated vertical saccades performance in dyslexic children. The results showed that, dyslexic children had longer latencies, poor precision and slow saccadic speed with up / down asymmetry. Studies 2 and 3 respectively allowed us to enlarge the investigation of visual fixation as well as visual-auditory phonological capabilities in dyslexic children. We reported a low quality of visual fixation and visual-auditory phonological recognition in children with dyslexia compared with the non-dyslexic children.Taken together, all these findings suggested, in dyslexic children, an immaturity of the magnocellular visual system, as well as of the cortico-subcortical structures responsible for oculomotor performances. Attentional capabilities, that are poor in dyslexic children, would be also explained their oculomotor deficiencies reported. Thus, we proposed oculomotor rehabilitation that could be able to improve reading skills in dyslexia.Key words: Eye movements, saccades, fixations, visual system, visual cortex, cortical and sub-cortical structures, attention, developmental dyslexia
Cosson, Emmanuel. "Intégrateurs de risque cardiovasculaire chez l’animal : rigidité et structure artérielles et fonction endothéliale : corrélations avec l’insulino-résistance, le système nerveux autonome et les adipocytokines". Paris 13, 2007. http://www.theses.fr/2007PA132030.
Testo completoArterial stiffness, arterial wall and endothelial function integrate exposure to the cardio-vascular risk factors. Blood pressure (BP), pulse wave velocity (PWV), autonomic nervous system (ANS) and their determinants were studied in Spontaneously Hypertensive Rats (SHR), Wistar-Kyoto rats (WKY), Zucker Diabetic Fatty rat (ZDF). BP, age and body weight correlated with PWV in SHR and WKY rats. In WKY rats, PWV negatively correlated with variability in pulse interval in the high frequencies (HF-PI), an index of vagal activity. PWV and BP increased with age in ZDF and Lean rats without differences between strains. HF-PI negatively correlated with PWV. Carotid wall was remodeled in ZDF rats. Wall structure characteristics correlated with adiponectin in ZDF rats. Rosiglitazone prevented the aortic and capillary endothelial dysfunction observed in the ZDF rats. To conclude, body weight determines PWV in the animal. ZDF rats do not exhibit high BP and arterial stiffness and therefore are not a good model for atherosclerosis. However, the present work suggests a role for vagal activity against arterial stiffness and of adipocytokines in arterial structure
Bocquet-Garçon, Annelise. "Modalités de recrutement des cellules microgliales dans le système nerveux central lésé chez la sangsue Hirudo medicinalis". Thesis, Lille 1, 2012. http://www.theses.fr/2012LIL10192/document.
Testo completoThe leech has the capacity to regenerate its central nervous system (CNS) following injury. After damage, the microglial cells migrate and accumulate at the lesion site, and this phenomenon is essential for the CNS repair. Moreover, two chemoattractant factors, HmIL-16 and HmC1q, which are mammalian IL-16 and C1q homologous, were identified in the leech CNS. In vertebrates, the IL-16 active form can recruit the immune CD4+ cells. Interestingly, our first chemotaxis assays showed that (i) human IL-16 recruits leech microglial cells (ii) HmIL-16 can exert a chemotactic activity on human CD4+ T cells. Taken together, the in vitro assays suggest the conservation of functional IL-16/CD4 interaction in leech. To confirm this hypothesis, the affinity purification using HmIL-16 demonstrated the interaction with a CD4-related protein in leech CNS. The human C1q recruits the immune cells via an interaction with two receptors named gC1qR (or C1qBP) and cC1qR. In the leech CNS, two proteins, HmC1qBP and HmcC1qR, present a high degree of homology with these human C1q receptors. In order to demonstrate the HmC1qBP and HmcC1qR implications in the leech microglial cells HmC1q-mediated recruitment, some in vitro chemotaxis assays were performed. These analyses were completed with immunohistochemistry experiments performed on crushed nerve cords. Finally, using the human C1q, HmC1qBP and HmcC1qR were purified by affinity. The presented work specifies the molecular processes which are involved in the microglial recruitment following lesions in the leech CNS. The data could help to understand the early phase of this response leading to a complete and functional CNS repair in the leech
Luccarini, Philippe. "Analyse des accompagnements posturaux associés à la flexion d'une patte chez le chat : modulation à partir du tegmentum pontique dorsolatéral et du noyau vestibulaire latéral". Aix-Marseille 1, 1991. http://www.theses.fr/1991AIX11369.
Testo completoBernuzzi, Viviane. "Contribution à l'étude expérimentale des effets d'intoxication aluminiques chez le rat : développement physique, maturation neuromotrice, comportement en situations d'apprentissage". Metz, 1988. http://docnum.univ-lorraine.fr/public/UPV-M/Theses/1988/Bernuzzi.Viviane.SMZ889.pdf.
Testo completoAluminum, a potent toxic substance of the central nervous system has been especially studied for 20 years in human clinic and animal experimentation. Yet, the scarcity of works in the ontegenetic field of aluminum intoxication lead us to study the effects of this element when applied to rats in early period of life : in utero by intoxication of the pregnant female (by aluminum chloride or lactate) or during the pre-weaning period (by aluminum lactate). A set of parameters including neuro-motor maturation tests and learning abilities tests were used in order to evaluate the short- and long-term consequences of these treatments. The results indicate that when treated in utero all the pups of a litter have losses of weight which include a post-natal letality under a critical level of birth weight. Surviving pups have an initial delay in their neuro-motor development which completely disappears in aluminum chloride treated rats. Aluminum lactate treated rats have some long term sequels, which are revealed by learning abilities tests (operant conditioning and spatial learning). Post-natally treated rats show the same syndrome at a greater degree. The dose-dependant weight losses which occur although the pups eat maternal milk seems imply a negative effect of Al upon the gastrointestinal tract. X-ray microanalysis indicates modifications of Zn and Cu levels and indicate the direction of further studies
Weber, Jacques. "Etudes anatomo-physiologiques du contrôle nerveux extrinsèque du tube digestif chez l'homme". Aix-Marseille 3, 1990. http://www.theses.fr/1990AIX30036.
Testo completoScotto, Lomassese Sophie. "La neurogénèse chez l'insecte adulte : régulation par l'environnement sensoriel et social et rôle fonctionnel". Aix-Marseille 1, 2002. http://www.theses.fr/2002AIX11033.
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