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Autore: Grafiati

Pubblicato: 25 luglio 2024

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1

Zhang, Xiangyu, Wei Jiang e Hongyu Zhao. "Integration of expression QTLs with fine mapping via SuSiE". PLOS Genetics 20, n. 1 (25 gennaio 2024): e1010929. http://dx.doi.org/10.1371/journal.pgen.1010929.

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Genome-wide association studies (GWASs) have achieved remarkable success in associating thousands of genetic variants with complex traits. However, the presence of linkage disequilibrium (LD) makes it challenging to identify the causal variants. To address this critical gap from association to causation, many fine-mapping methods have been proposed to assign well-calibrated probabilities of causality to candidate variants, taking into account the underlying LD pattern. In this manuscript, we introduce a statistical framework that incorporates expression quantitative trait locus (eQTL) information to fine-mapping, built on the sum of single-effects (SuSiE) regression model. Our new method, SuSiE2, connects two SuSiE models, one for eQTL analysis and one for genetic fine-mapping. This is achieved by first computing the posterior inclusion probabilities (PIPs) from an eQTL-based SuSiE model with the expression level of the candidate gene as the phenotype. These calculated PIPs are then utilized as prior inclusion probabilities for risk variants in another SuSiE model for the trait of interest. By prioritizing functional variants within the candidate region using eQTL information, SuSiE2 improves SuSiE by increasing the detection rate of causal SNPs and reducing the average size of credible sets. We compared the performance of SuSiE2 with other multi-trait fine-mapping methods with respect to power, coverage, and precision through simulations and applications to the GWAS results of Alzheimer’s disease (AD) and body mass index (BMI). Our results demonstrate the better performance of SuSiE2, both when the in-sample linkage disequilibrium (LD) matrix and an external reference panel is used in inference.

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2

Arianto, Setio Boedi. "Kajian Kereta Api Komuter Surabaya - Sidoarjo (Susi) Sebagai Angkutan Umum Massal Di Surabaya". Warta Penelitian Perhubungan 22, n. 8 (31 agosto 2010): 798–807. http://dx.doi.org/10.25104/warlit.v22i8.1139.

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Tir purpGfe of this stud!; is to make rm1mn; 115 mnss tmnsportntion tlmt nJ71m;s re needed l:n; tl7e Sumbcn.Jfland Sidoarjo residents. By using trend analysis n7etlwd and qual.itntirie descriptive analysis, it can ~amduded that tl7e pref£r!Ce of Susi Railwm; only m;Wle of amying 0.29% of tl7e total population Sidmrjoand Surabat;a, sud1 a little number or inadequate mass transportation fur a tm1m like Surabat;a andSidmrjo wit/1 a total population of 4,711,160 inhabitants. Susie trajecton; railwm; tracks alxJut 69% arestill single track and 31 % is double track Tizis rondition influence tl7e qunlity of EmTices to tl7e U£erS of railtransrxJrt, ~muse tl7ere are many patl?S tlmt Junie not lx:en double trnck milwm;, so tl7e journei; of Susie hasto m:zit for anotlv train to pass and then milway am rontinue the Susie joun1e1J Tizis rondition will affecttl7e trmiel Edrdule of Susie train. 771f nu nm of patl?S or routes Susi train is only 1 track, namely Sumbcn.Jfl- Porung via: z:ersa. T71f quantity nu~ of routes tlmt only one is nm; less if you lwie to Eenie tl7e nu~of passengers wlw Jwie different purpGfes. But wl1fn vienied from tl7e plrysiad rondition of station infrastructureshelter is still in good rondition. Ow tJ7e last faie years (2005 - 2009) Susie has experienceddedining passengers ~muse tJ7e nwst of passengers wlw mn1f from Sidmrjo and Porvng f1£IZI(! ~mud.flow disaster, so many tl1e1; nwzie tl1fir residence. So the consequence, tJ1e11 switd1 to anotlv modelmiuse of tl7e Edzedule Susie train are mrely an time, nlso tlie lomtions tllnt senie tlJE milwm; station are notronnected or ezien less to ronnected witl1 feeder netnorks tlmt exist so tlmt users Susie commuter railtransportation often experienced difficulty in using Susie train to reach its final destination.

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3

Editors, Policy Perspectives. "Susie Saavedra". Policy Perspectives 25 (11 maggio 2018): 84–90. http://dx.doi.org/10.4079/pp.v25i0.18393.

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Susie Saavedra was recently promoted to Vice President for Policy and Legislative Affairs at the National Urban League Washington Bureau. Prior to this role, she served as Senior Director for the same department. Specifically, Ms. Saavedra is the League’s chief education and health policy officer, a responsibility she has held since 2013. She offers over 15 years of federal legislative, policy, and political experience along with a passion for advancing social and economic justice. Before joining the National Urban League, Ms. Saavedra spent a decade working in both the United States House of Representatives and United States Senate for four Members of Congress, as a Legislative Aide to former Senator Hillary Clinton, and as a Legislative Director for Representatives Karen Bass, Al Green and Joe Baca. She also promoted diversity in the halls of Congress as former President of the Congressional Hispanic Staff Association (CHSA) and has advocated for expanding opportunities for Hispanics in higher education as a governing board member of the Hispanic Association of Colleges and Universities (HACU). Ms. Saavedra is also the Vice President of the Hispanic Lobbyists Association which is dedicated to building diversity in the government relations profession. She holds a Master of Public Administration degree from George Washington University and a Bachelor of Arts degree from the University of Denver.

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4

Tompkins, Susie, e Mary Scott. "Interview: Susie Tompkins". Business Ethics: The Magazine of Corporate Responsibility 9, n. 1 (1995): 20–23. http://dx.doi.org/10.5840/bemag1995917.

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5

Susie, Sister. "Susie transmits diseases". Nursing Standard 8, n. 22 (23 febbraio 1994): 45. http://dx.doi.org/10.7748/ns.8.22.45.s51.

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6

Thornton, Susie. "The Susie Corset". Physiotherapy 79, n. 12 (dicembre 1993): 876. http://dx.doi.org/10.1016/s0031-9406(10)60149-6.

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7

Susie, Sister. "Susie: terminal care specialist". Nursing Standard 8, n. 31 (27 aprile 1994): 45. http://dx.doi.org/10.7748/ns.8.31.45.s56.

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8

Susie, Sister. "Susie goes Grammy bashing". Nursing Standard 7, n. 43 (14 luglio 1993): 46. http://dx.doi.org/10.7748/ns.7.43.46.s61.

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9

Atayurt, Zeynep Z. "Bodies by Susie Orbach". Journal of Popular Culture 43, n. 1 (febbraio 2010): 195–96. http://dx.doi.org/10.1111/j.1540-5931.2010.00737.x.

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10

Kay, Ann C. "Why Susie Can't Sing". Music Educators Journal 84, n. 4 (gennaio 1998): 45–46. http://dx.doi.org/10.1177/002743219808400402.

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11

Turró, Carla. "Entrevista con Susie Orbach". Clínica e Investigación Relacional 07, n. 2 (1 luglio 2013): 424–27. http://dx.doi.org/10.21110/19882939.2013.070214.

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12

Simpson, Pamela, Bryn Youds, Jill Oakes e Rick Riewe. "Susie Cooper: An Elegant Affair". Woman's Art Journal 20, n. 1 (1999): 65. http://dx.doi.org/10.2307/1358854.

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13

Sanderson OBE, Susie. "Expert view: Susie Sanderson OBE". British Dental Journal 231, n. 1 (luglio 2021): 31. http://dx.doi.org/10.1038/s41415-021-3244-0.

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14

TYSON, JANET STILES. "MELISSA MILLER BY SUSIE KALIL". Art Book 15, n. 4 (novembre 2008): 41–42. http://dx.doi.org/10.1111/j.1467-8357.2008.00992_8.x.

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15

Harzoune, Mustapha. "Susie Steiner, Garde le silence". Hommes & migrations, n. 1340 (1 gennaio 2023): 210. http://dx.doi.org/10.4000/hommesmigrations.15204.

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16

Verow, Susie. "The essential skill of sedation". Dental Nursing 16, n. 1 (2 gennaio 2020): 42–43. http://dx.doi.org/10.12968/denn.2020.16.1.42.

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17

Zou, Yuxin, Peter Carbonetto, Gao Wang e Matthew Stephens. "Fine-mapping from summary data with the “Sum of Single Effects” model". PLOS Genetics 18, n. 7 (19 luglio 2022): e1010299. http://dx.doi.org/10.1371/journal.pgen.1010299.

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Abstract (sommario):

In recent work, Wang et al introduced the “Sum of Single Effects” (SuSiE) model, and showed that it provides a simple and efficient approach to fine-mapping genetic variants from individual-level data. Here we present new methods for fitting the SuSiE model to summary data, for example to single-SNP z-scores from an association study and linkage disequilibrium (LD) values estimated from a suitable reference panel. To develop these new methods, we first describe a simple, generic strategy for extending any individual-level data method to deal with summary data. The key idea is to replace the usual regression likelihood with an analogous likelihood based on summary data. We show that existing fine-mapping methods such as FINEMAP and CAVIAR also (implicitly) use this strategy, but in different ways, and so this provides a common framework for understanding different methods for fine-mapping. We investigate other common practical issues in fine-mapping with summary data, including problems caused by inconsistencies between the z-scores and LD estimates, and we develop diagnostics to identify these inconsistencies. We also present a new refinement procedure that improves model fits in some data sets, and hence improves overall reliability of the SuSiE fine-mapping results. Detailed evaluations of fine-mapping methods in a range of simulated data sets show that SuSiE applied to summary data is competitive, in both speed and accuracy, with the best available fine-mapping methods for summary data.

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18

Wallace, Chris. "A more accurate method for colocalisation analysis allowing for multiple causal variants". PLOS Genetics 17, n. 9 (29 settembre 2021): e1009440. http://dx.doi.org/10.1371/journal.pgen.1009440.

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In genome-wide association studies (GWAS) it is now common to search for, and find, multiple causal variants located in close proximity. It has also become standard to ask whether different traits share the same causal variants, but one of the popular methods to answer this question, coloc, makes the simplifying assumption that only a single causal variant exists for any given trait in any genomic region. Here, we examine the potential of the recently proposed Sum of Single Effects (SuSiE) regression framework, which can be used for fine-mapping genetic signals, for use with coloc. SuSiE is a novel approach that allows evidence for association at multiple causal variants to be evaluated simultaneously, whilst separating the statistical support for each variant conditional on the causal signal being considered. We show this results in more accurate coloc inference than other proposals to adapt coloc for multiple causal variants based on conditioning. We therefore recommend that coloc be used in combination with SuSiE to optimise accuracy of colocalisation analyses when multiple causal variants exist.

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19

Jeffery, Sarah. "‘Protokols’: Von Nohrfeldt at Rewire Festival, Den Haag". Tempo 69, n. 272 (aprile 2015): 74–77. http://dx.doi.org/10.1017/s0040298214001132.

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20

Harrison, Antonia. "Tempus Mutatum (Time/change): Susie MacMurray". TEXTILE 7, n. 3 (novembre 2009): 366–69. http://dx.doi.org/10.2752/147597509x12541451110116.

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21

Elliott, Nathan R. "Susie Taylor. Even Weirder Than Before". Newfoundland and Labrador Studies 35, n. 1-2 (28 aprile 2021): 162–65. http://dx.doi.org/10.7202/1076777ar.

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22

Sahn, Sarah. "Stack the Cats by Susie Ghahremani". Bulletin of the Center for Children's Books 70, n. 9 (2017): 411–12. http://dx.doi.org/10.1353/bcc.2017.0356.

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23

Bush, Elizabeth. "Balance the Birds by Susie Ghahremani". Bulletin of the Center for Children's Books 72, n. 3 (2018): 121–22. http://dx.doi.org/10.1353/bcc.2018.0753.

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24

Starkman, Holly. "Interview with Susie Orbach, Ph.D., C.S.W." Clinical Social Work Journal 44, n. 1 (21 agosto 2015): 4–7. http://dx.doi.org/10.1007/s10615-015-0558-x.

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25

Branyan, Helen Baird. "Susie of American Tent Repertoire Theatre". Journal of Popular Culture 22, n. 4 (marzo 1989): 141–47. http://dx.doi.org/10.1111/j.0022-3840.1989.2204_141.x.

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26

Murray, Mark. "To: Susie White, PhD RN CPHQ". Journal For Healthcare Quality 24, n. 6 (novembre 2002): 38. http://dx.doi.org/10.1111/j.1945-1474.2002.tb01015.x.

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27

Seale, Douglas. "Susie Jacobs: Gender and Agrarian Reforms". Journal of Agricultural and Environmental Ethics 26, n. 4 (20 luglio 2012): 917–19. http://dx.doi.org/10.1007/s10806-012-9416-9.

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28

Abrams, Oona. "Connecting with Readers on Twitter: Chatting with Members of the #Read4Fun Community". English Leadership Quarterly 39, n. 2 (1 ottobre 2016): 10–11. http://dx.doi.org/10.58680/elq201628779.

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29

Barbosa Cruz, R. Mario. "Susie S. Porter, From Angel to Office Worker. Middle-Class Identity and Female Consciousness in Mexico, 1890–1950". Estudios de Historia Moderna y Contemporánea de México, n. 57 (28 novembre 2019): 294. http://dx.doi.org/10.22201/iih.24485004e.2019.57.69788.

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30

Thomas, David, e Susie Barrett. "Fighting TB in underserved populations: homeless communities". British Journal of Nursing 30, n. 1 (14 gennaio 2021): 24–26. http://dx.doi.org/10.12968/bjon.2021.30.1.24.

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Abstract (sommario):

David Thomas, TB Nurse Consultant, University Hospitals Dorset, david.thomas@uhd.nhs.uk , was runner-up, along with Susie Barrett in the Infection Control Nurse of the Year category of the BJN Awards 2020

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31

Hansen, Jan Erik. "Et zoom på online-undervisning". Revy 43, n. 3 (9 settembre 2020): 10–13. http://dx.doi.org/10.22439/revy.v43i3.6047.

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Interview med informationsspecialister og undervisere, Annemette Møller Hansen og Susie Rimborg. Vi taler online-undervisning og hvordan corona-tiden også blev et strategisk tigerspring for dem selv - og for Københavns Universitetsbibliotek.

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32

Susie. "Susie togs on and fights with bytes". Nursing Standard 8, n. 27 (30 marzo 1994): 44. http://dx.doi.org/10.7748/ns.8.27.44.s56.

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33

Westgarth, David. "Susie, Roz and Liz: A presidential debate". BDJ In Practice 34, n. 3 (marzo 2021): 9–11. http://dx.doi.org/10.1038/s41404-021-0680-0.

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34

Park, Martha. "Doggamut: A Day with Susie and Brown". Ecotone 12, n. 2 (2017): 52–56. http://dx.doi.org/10.1353/ect.2017.0008.

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35

Kilby, Jane. "Saving the girl: A creative reading of Alice Sebold’s Lucky and The Lovely Bones". Feminist Theory 19, n. 3 (22 aprile 2018): 323–43. http://dx.doi.org/10.1177/1464700117752773.

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Abstract (sommario):

In the late 1990s, Alice Sebold is writing what will become her phenomenally successful novel The Lovely Bones (2002), but she finds herself having to abandon it in order to write her critically acclaimed rape memoir Lucky (1999). She did not want, she says years later, Susie Salmon (the novel’s dead narrator) doing “work for her”, but wanted Susie free “to tell her own story”. Lucky would be the “real deal” about rape, while The Lovely Bones would be a fantasy. And yet, the memoir and novel are similar in many respects; and nearly identical to begin with. The Lovely Bones opens with the rape, murder and mutilation of a young girl – Susie – while Lucky opens with reference to the girl who was raped, murdered and mutilated in the tunnel Sebold was also raped in. This girl, Sebold maintains, always haunts her. Thus, I will argue, it is not possible to read her novel, which some critics have dismissed as “timid and sentimental”, without reading her gritty autobiography; and vice versa it is not possible to read Sebold’s rape memoir without reading her novel, which in a complex way bears witness to that unnamed girl, if not for all dead, unnamed girls. The question is, then, how does the intertextuality of Sebold’s novel and memoir, and, more broadly, the interrelationship of truth and fantasy, impact on our reading of Sebold’s work, especially her memoir? Keywords Rape, fact, fiction, truth, lie, reading, writing, creative witnessing, wishful thinking, utopia

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36

Wool, Zoë H. "War sick". Focaal 2013, n. 66 (1 giugno 2013): 139–47. http://dx.doi.org/10.3167/fcl.2013.660112.

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Finley, Erin. 2011. Fields of combat: Understanding PTSD among veterans of Iraq and Afghanistan. Ithaca, NY: Cornell University Press. 240 pages.Kilshaw, Susie. 2009. Impotent warriors: Gulf War syndrome, vulnerability and masculinity. Oxford: Berghahn Books. 282 pages.

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37

Naylor, Shano. "Boomchee". After Dinner Conversation 2, n. 1 (2021): 5–14. http://dx.doi.org/10.5840/adc2021212.

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At what point in a date do you owe the other party the duty to inform them you are engaged? Is marriage an exercise in love, or practicality? In this work of philosophical short story fiction, the law school student narrator working at a summer factory job decides to set up her shy female friend, Susie, with her boyfriend’s shy brother, Barry. They go on a double date and everything seems to be going fine. Only later does the narrator and her boyfriend find out that Barry is engaged to a mail-order bride from Southeast Asia that will be arriving shortly. The shy Barry, it turns out, wanted to “practice” going on a date before his new wife arrived. The law student narrator is embarrassed, and struggles with the moral duty both she, and Barry, owe to Susie.

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38

Lim, Wesley. "Breathing Back the History of German Modern Dance through the Horror Film Genre in Luca Guadagnino's Suspiria (2018)". Dance Research Journal 55, n. 1 (aprile 2023): 81–97. http://dx.doi.org/10.1017/s0149767723000177.

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Director Luca Guadagnino's film Suspiria (2018) depicts the dancer Susie Bannion joining a dance academy secretly run by a coven of witches in Berlin during the German Autumn of 1977. This article analyzes how Mary Wigman's Hexentanz II, contemporary dance, and horror film practices inform Susie's neo-expressionist movement form, which is also steeped in the discourse surrounding the RAF (Red Army Faction), the West German far-left militant organization, and fascism. I argue that “historical breathing”—breaths and sighs—takes on a sensorial mode by surveying the past and current situation of the dance school. By inhaling, Susie embodies the dance Volk (1948) and can feel its vexed choreographic history—its occult origins and Ausdruckstanz practices. Furthermore, her dance futilely attempts to comes to terms with the Nazi past but inevitably replicates the violence of the RAF.

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Naylor, Shani. "Boomchee". After Dinner Conversation 4, n. 4 (2023): 108–19. http://dx.doi.org/10.5840/adc20234438.

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Abstract (sommario):

At what point in a date do you owe the other party the duty to inform them you are engaged? Is marriage an exercise in love, or practicality? In this work of philosophical short story fiction, the law school student narrator working at a summer factory job decides to set up her shy female friend, Susie, with her boyfriend’s shy brother, Barry. They go on a double date and everything seems to be going fine. Only later does the narrator and her boyfriend find out that Barry is engaged to a mail-order bride from Southeast Asia that will be arriving shortly. The shy Barry, it turns out, wanted to “practice” going on a date before his new wife arrived. The law student narrator is embarrassed, and struggles with the moral duty both she, and Barry, owe to Susie.

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40

Coverley, Hannah, Lady Jo Reyes, Susie Verow e Jason Wong. "It's back to work we go…". Dental Nursing 16, n. 8 (2 agosto 2020): 382–83. http://dx.doi.org/10.12968/denn.2020.16.8.382.

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Dental nurse Hannah Coverley talks about her return to practice with colleagues Lady Jo Reyes and Susie Verow at The Maltings Dental Practice in Grantham, Lincolnshire, as they worked alongside newly appointed deputy chief dental officer for England, Jason Wong to welcome back their patients

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Sabin, Margery. "Review: Anthologies of Modern Indian Literature". College English 68, n. 1 (1 settembre 2005): 90–106. http://dx.doi.org/10.58680/ce20054102.

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Reviewed are The Vintage Book of Modern Indian Literature, edited by Amit Chaudhuri; Mirrorwork: Fifty Years of Indian Writing, 1947–1997, edited by Salman Rushdie and Elizabeth West; and Women Writing in India, Vol. 2: The Twentieth Century, edited by K. Lalita and Susie Tharu.

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42

Nisrina, Nabilah, e Hadiyanto Hadiyanto. "Lindsey Salmon’s Mourning Process in Facing Sister’s Death in Alis Sebold’s The Lovely Bones". Culturalistics: Journal of Cultural, Literary, and Linguistic Studies 5, n. 2 (1 luglio 2021): 60–67. http://dx.doi.org/10.14710/culturalistics.v5i2.12481.

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This study analyzes the mourning process of Lindsey Salmon, one of the characters in Alice Sebold’s “The Lovely Bones”. This study aims to analyze the character of Lindsey Salmon, the conflicts experienced by Lindsey Salmon, and to identify Lindsey Salmon’s mourning process in coping with Susie Salmon’s death. The writer applies psychological approach to analyze Lindsey Salmon’s process of mourning to Susie Salmon’s death by using J. William Worden’s theory named “the Four Tasks of Mourning”. The result of the study shows Lindsey Salmon’s mourning process through four tasks: accepting the reality of the loss, processing the pain of the grief, adjusting to a world without the deceased, and finding an enduring connection with the deceased in the midst of embarking on a new life. From this study, it can be concluded that even though it takes her a long time, Lindsey Salmon is capable of overcoming her grief over Susie’s death and moving on with her life.Keywords: character; conflict; four tasks of mourning

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Parker, Diane L., e Anthony J. Picard. "Portraits of Susie: Matching Curriculum, Instruction, Find Assessment". Teaching Children Mathematics 3, n. 7 (marzo 1997): 376–82. http://dx.doi.org/10.5951/tcm.3.7.0376.

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Assessment can be thought of as an attempt to create a portrait of a student's learning. But portraits can vary according to what the artist chooses to focus on, and assessment portraits are no different in this respect. In this article, we examine two assessment portraits of one student and show how they relate to issues of curriculum and instruction.

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44

Al-Mohammad, Hayder. "Making sense of everyday life - By Susie Scott". Journal of the Royal Anthropological Institute 16, n. 4 (3 novembre 2010): 935–36. http://dx.doi.org/10.1111/j.1467-9655.2010.01661_29.x.

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Pham, Minh-Ha T. "“Susie Bubble is a Sign of The Times”". Feminist Media Studies 13, n. 2 (maggio 2013): 245–67. http://dx.doi.org/10.1080/14680777.2012.678076.

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Orbach, Susie. "Therapy from the left: interview with Susie Orbach". European Journal of Psychotherapy & Counselling 6, n. 1 (marzo 2003): 75–85. http://dx.doi.org/10.1080/1364253032000157080.

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47

Calvo Manuel, Ana. "Trade in Artists’ Materials. Markets and Commerce in Europe to 1700." Ge-conservacion 2 (9 dicembre 2011): 166–68. http://dx.doi.org/10.37558/gec.v2i2.49.

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Reseña del libro:Trade in Artists’ Materials. Markets and Commerce in Europe to 1700. Edited by Jo Kirby, Susie Nash y Joanna Cannon Archetype Publications Ltd. Londres, 2010 509 páginas, ilustraciones en color y blanco y negro, 297 x 210 mm., pasta dura ISBN: 978-1-904982-25-8

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McRobbie, Angela. "A Response to Susie Orbach: On Generation and Femininity". Studies in Gender and Sexuality 9, n. 3 (30 giugno 2008): 239–45. http://dx.doi.org/10.1080/15240650802117838.

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Tota, Anna Lisa. "Book review: Susie Scott, Making Sense of Everyday Life". Qualitative Research 11, n. 6 (dicembre 2011): 765–66. http://dx.doi.org/10.1177/1468794111412265.

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Bloor, Michael. "Book Review: Susie Scott, Total Institutions and Reinvented Identities". Qualitative Research 13, n. 3 (29 maggio 2013): 385–86. http://dx.doi.org/10.1177/1468794113475418.

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