Libri sul tema "Structure-Based approaches"

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1

Merz, Kenneth M. Drug design: Structure- and ligand-based approaches. Cambridge [U.K.]: Cambridge University Press, 2010.

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2

1959-, Merz Kenneth M., Ringe Dagmar e Reynolds Charles H. 1957-, a cura di. Drug design: Structure and ligand-based approaches. Cambridge: Cambridge University Press, 2010.

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3

W, Codding Penelope, North Atlantic Treaty Organization. Scientific Affairs Division. e NATO Advanced Study Institute on Experimental and Computational Approaches to Structure-Based Drug Design (1996 : Erice, Italy), a cura di. Structure-based drug design: Experimental and computational approaches. Dordrecht: Kluwer Academic Publishers, 1998.

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4

1967-, Meurers W. Detmar, e Kiss Tibor 1962-, a cura di. Constraint-based approaches to Germanic syntax. Stanford, Calif: CSLI Publications, 2001.

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5

Gunji, Takao. Japanese phrase structure grammar: A unification-based approach. Dordrecht, Holland: D. Reidel, 1987.

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6

Papadopoulos, Alexandra. Standards-based curriculum and assessment prototypes: An eye on structure. Sea Cliff, NY: Center for the Study of Expertise in Teaching and Learning, 2005.

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7

Simpson, Jeffrey H. Organic structure determination using 2-D NMR spectroscopy: A problem-based approach. 2a ed. Waltham, MA: Academic Press, 2012.

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8

Hart, David K. Fundamentals of the structure and history of Russian: A usage-based approach. Bloomington, Indiana: Slavica, 2013.

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9

Alderson, Michael J. An integrated model of corporate pension policy and capital structure decision: A liability-based approach. [Urbana, Ill.]: College of Commerce and Business Administration, University of Illinois at Urbana-Champaign, 1986.

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10

McCoy, Dennis Bryan. Identity transition in persons undergoing elective interval sterilisation and vasectomy: An approach based on identity structure analysis. [s.l: The author], 1986.

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11

Donnelly, Stephen Kevin. Ethnic identity redefinition during acquisition of one's ancestral language (Irish): An approach based on identity structure analysis. [s.l: The Author], 1994.

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12

Tarakanov, Andrey, A. Sumin e A. Hvostov. Mathematical problems of decision-making in dynamic organizational systems. ru: INFRA-M Academic Publishing LLC., 2023. http://dx.doi.org/10.12737/1871445.

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The monograph develops the theory of decision-making in dynamic organizational systems with a complex structure in conditions of conflict and uncertainty. An overview of the current state of the theory is given. The systems are studied: hierarchical, coalition and coalition-hierarchical (hybrid). The main attention in the process of constructing mathematical models of systems is paid to the description of ways of information interaction of decision makers. At the same time, the variants of their unfavorable (conflict) and benevolent "attitude" to each other are taken into account. Two approaches to decision-making based on the principle of guaranteed results and approaches of game theory are proposed. Exactly: 1) making decisions from the point of view of a dedicated participant in the system based on penalty functions and obtaining the necessary optimality conditions; 2) making decisions based on special optimality principles constructed using the principles of Nash, Pareto, Joffrion, Stackelberg, Slater, threats — counter-threats and obtaining sufficient optimality conditions. Some theoretical results are illustrated by model examples. For researchers, postgraduates and students dealing with theoretical and practical issues of decision-making in complex systems.
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13

Bacchereti, Elisabetta, Federico Fastelli e Diego Salvadori, a cura di. Il graphic novel. Un crossover per la modernità. Florence: Firenze University Press, 2020. http://dx.doi.org/10.36253/978-88-5518-221-8.

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The graphic novel is one of the most suggestive and successful semiotic phenomena. This collection of essays focuses on the interrelations of image and text, and how they are substantiated and thematized by graphic novels. The volume gathers together twelve essays and follows a twofold structure: a historical and theoretical one, providing different and complementary approaches to the topic, from neurocognitive narratology to Digital Humanities; in the second part of the volume several case studies are discussed, based on key examples as shown by the following authors and their work: from Vanna Vinci and Lorenza Natarella, to Gipi, Zerocalcare and Manuel Fior; from Dino Buzzati to Hugo Pratt and Pazienza; from Pablo Echaurren to the Homeric epics’ comics remediation.
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14

Prokof'ev, Stanislav, Ekaterina Kameneva, Svetlana Solyannikova, Elena Didenko, Gul'nara Ruchkina, Natal'ya Sergeeva, Marina Abramova et al. Ecosystem of universities: transformation of the Russian education system. ru: INFRA-M Academic Publishing LLC., 2022. http://dx.doi.org/10.12737/1901313.

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The relevance of the monograph is determined by changes in the surrounding reality, the development of the digital economy, which actively influences the formation and development of ecosystems of business, banking, public services, etc.; the need to determine the main trends in the development of the modern ecosystem of universities for the formation of in-demand graduates able to work in the special conditions of modern development of Russia, which determines the formation of a new educational environment, based on the challenges facing our country. All this will contribute to a deeper and more comprehensive study of the structure of the university ecosystem, understanding its features due to the realities of the digital space. An overview of the features of the factors affecting the field of education, including the ecosystems already existing today in various spheres of the Russian economy, is presented. Proposals are made for the formation of a competence-based approach in the university environment in modern conditions. The main elements of the university ecosystem as a new model of the educational environment are considered. Special attention is paid to the development of the university ecosystem of personnel partnership and continuing education. The author's approaches to assessing the quality of education are proposed. The legislation is given as of July 1 , 2022 . It may be of interest to heads of the education system, teachers of higher educational institutions, teachers, employees of organizations of additional professional education, graduate students, undergraduates and students of pedagogical and psychological educational institutions.
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15

Lomakina, Tat'yana, e Nina Vasil'chenko. Modern technology of teaching a foreign language: design and experience. ru: INFRA-M Academic Publishing LLC., 2021. http://dx.doi.org/10.12737/1111366.

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The monograph deals with the theoretical and practical issues of pedagogical design of the technology of teaching a foreign language in the system of secondary vocational education. Presents an analysis of key concepts "instructional design" and "technology of education" that is meaningful and reveals the basic principles of the system, activity-based and student-centered approaches to the design of learning technologies to address new opportunities and the status of the str system in the modern socio-economic conditions. The author has developed a method of selection of the content of learning English language, based on the modular structure of the course, taking into account international experience in building the content of language education for professional purposes, the requirements of the educational-methodical complex of teaching business English and core competencies stipulated by the Council of Europe, as well as the requirements of the labour market and the needs of employers standardisert, intensificarea language training specialist of middle management by reflection of the status and trends of professional activities in various fields. For use in the system of professional development of teachers of secondary vocational education, additional education and the system of corporate training.
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16

Grassini, Maurizio, e Rossella Bardazzi, a cura di. Structural changes, international trade and multisectoral modelling. Florence: Firenze University Press, 2008. http://dx.doi.org/10.36253/978-88-8453-740-9.

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In September 2007 the national team members of the International Inforum (Interindustry Forecasting Project at the University of Maryland) group held the XV annual World Conference in Truijllo, Spain. Such Conferences offer the participants to report their achievements in the different fields concerning the macroeconomic multisectoral modeling approach and data development. The national partners build their country model based on a common input-output accounting structure and a similar econometric modeling approach for sectoral and macroeconomic variables. In each Conference, the contributions refer to the wide spectrum of research activities carried on within the Inforum system of models.
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17

Kovalenko, Vladimir. Design of information systems. ru: INFRA-M Academic Publishing LLC., 2020. http://dx.doi.org/10.12737/987869.

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The tutorial discusses the design features of information systems (is) involved in the implementation of CALS technologies: MRP/MRPII/ERP systems, e-Commerce systems (B2B), supply chain management (SCM), customer relationship management (CRM), and decision support systems (OLAP). The issues of choosing the design technology, software tools for project development, building functional and information models in the environment of Business Studio, MS Visio, Elma, AllFusion Modeling Suite and Oracle Designer 10g, as well as the development of technical and operational documentation are highlighted. The characteristics of CASE technologies and their implementation in the Oracle Designer 10g environment are considered. A comparative analysis of the standards of the organization of the life cycle of creating and using IP, practical recommendations for the development of standard profiles, examples of the development of an IP project based on a cascading model of the life cycle, including using a process approach in the management and automation of processes. The models of the client — server architecture and the structure of cloud computing are considered. Modern approaches to the selection of ready-made is and their implementation in automated enterprises are studied in detail. Meets the requirements of the Federal state educational standards of higher education of the latest generation. It is intended for students (bachelors and specialists) and masters of higher educational institutions studying in the direction of "Applied Informatics". It is also recommended for teachers and specialists working in the field of information technology.
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18

Kenneth M. Merz Jr PhD, Dagmar Ringe PhD e Charles H. Reynolds PhD. Drug Design: Structure- and Ligand-Based Approaches. Cambridge University Press, 2010.

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19

Reynolds, Charles H., Dagmar Ringe e Kenneth M. Merz. Drug Design: Structure- and Ligand-Based Approaches. Cambridge University Press, 2010.

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20

Reynolds, Charles H., Dagmar Ringe e Merz Kenneth M. Jr. Drug Design: Structure- and Ligand-Based Approaches. Cambridge University Press, 2010.

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21

Reynolds, Charles H., Dagmar Ringe e Merz Kenneth M. Jr. Drug Design: Structure- and Ligand-Based Approaches. Cambridge University Press, 2006.

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22

Codding, P. W. Structure-Based Drug Design: Experimental and Computational Approaches. Springer Netherlands, 2010.

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23

Codding, P. W. Structure-Based Drug Design: Experimental and Computational Approaches. Springer, 2014.

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24

Codding, P. W. Structure-Based Drug Design Experimental and Computational Approaches. Springer, 1998.

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25

Codding, P. W. Structure-Based Drug Design: Experimental and Computational Approaches. Springer London, Limited, 2013.

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26

Andricopulo, Adriano D., e Leonardo L. G. Ferreira, a cura di. Chemoinformatics Approaches to Structure- and Ligand-Based Drug Design. Frontiers Media SA, 2019. http://dx.doi.org/10.3389/978-2-88945-744-1.

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27

Egbuna, Chukwuebuka, e Mithun Rudrapal. Computer Aided Drug Deisgn: From Ligand-Based Methods to Structure-Based Approaches. Elsevier, 2022.

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28

Egbuna, Chukwuebuka, e Mithun Rudrapal. Computer Aided Drug Deisgn: From Ligand-Based Methods to Structure-Based Approaches. Elsevier, 2022.

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29

Computer Aided Drug Design (CADD): From Ligand-Based Methods to Structure-Based Approaches. Elsevier, 2022. http://dx.doi.org/10.1016/c2020-0-04039-9.

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30

Andricopulo, Adriano D., e Leonardo L. G. Ferreira, a cura di. Chemoinformatics Approaches to Structure- and Ligand-Based Drug Design, Volume II. Frontiers Media SA, 2022. http://dx.doi.org/10.3389/978-2-88976-631-4.

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31

Velleman, Leah, e David Beaver. Question-based Models of Information Structure. A cura di Caroline Féry e Shinichiro Ishihara. Oxford University Press, 2015. http://dx.doi.org/10.1093/oxfordhb/9780199642670.013.29.

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Abstract (sommario):
We present approaches to the semantics and pragmatics of information structure which centre on Questions Under Discussion (QUDs). Questions, explicit or implicit, are seen as structuring discourse, and information structural marking is seen as reflecting that underlying discourse structure. Our presentation of the model is largely cast in terms of extensions of Roberts’s (2012b) analysis, which is itself related to Rooth’s (1985/1992) Alternative Semantics and Hamblin’s (1973) approach to the semantics of questions. We present the model in terms of a range of constraints that relate information structure to discourse structure, notably constraints on the ‘Relevance’ of utterances, on the ‘Congruence’ of answers to questions, and on the ‘Availability’ of discourse antecedents. We discuss the application of the approach to the interpretation of focus and some cases of contrastive topics, to discourse structure, to the interpretation of focus sensitive operators, and to certain cases of presupposition projection.
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32

Poppe, Andrew, e Angus W. MacDonald III. Cognitive Neuroscience Approaches to Personality Disorders. A cura di Christian Schmahl, K. Luan Phan, Robert O. Friedel e Larry J. Siever. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199362318.003.0004.

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This chapter describes a cognitive neuroscience approach to understanding the psychological and neural processes that underlie personality and behavior. It explicates the utility of the cognitive neuroscience approach and the fundamental principles of the methods and how to interpret the findings. The chapter reviews the different neuroimaging tools and approaches that can be used to investigate brain structure and function. In doing so, it provides detailed information about what each method measures and how issues to consider when evaluating these measurements and their functional significance. The chapter provides the reader an appreciation of how understanding brain structure and function in vivo can serve as a bridge between molecular/genetic and symptom-based data to enrich the pathophysiology of personality disorders.
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33

Meurers, W. Detmar, e Tibor Kiss. Constraint-Based Approaches to Germanic Syntax. CSLI Publications/Center for the Study of Language & Information, 2022.

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34

Kirchman, David L. Community structure of microbes in natural environments. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198789406.003.0004.

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Community structure refers to the taxonomic types of microbes and their relative abundance in an environment. This chapter focuses on bacteria with a few words about fungi; protists and viruses are discussed in Chapters 9 and 10. Traditional methods for identifying microbes rely on biochemical testing of phenotype observable in the laboratory. Even for cultivated microbes and larger organisms, the traditional, phenotype approach has been replaced by comparing sequences of specific genes, those for 16S rRNA (archaea and bacteria) or 18S rRNA (microbial eukaryotes). Cultivation-independent approaches based on 16S rRNA gene sequencing have revealed that natural microbial communities have a few abundant types and many rare ones. These organisms differ substantially from those that can be grown in the laboratory using cultivation-dependent approaches. The abundant types of microbes found in soils, freshwater lakes, and oceans all differ. Once thought to be confined to extreme habitats, Archaea are now known to occur everywhere, but are particularly abundant in the deep ocean, where they make up as much as 50% of the total microbial abundance. Dispersal of bacteria and other small microbes is thought to be easy, leading to the Bass Becking hypothesis that “everything is everywhere, but the environment selects.” Among several factors known to affect community structure, salinity and temperature are very important, as is pH especially in soils. In addition to bottom-up factors, both top-down factors, grazing and viral lysis, also shape community structure. According to the Kill the Winner hypothesis, viruses select for fast-growing types, allowing slower growing defensive specialists to survive. Cultivation-independent approaches indicate that fungi are more diverse than previously appreciated, but they are less diverse than bacteria, especially in aquatic habitats. The community structure of fungi is affected by many of the same factors shaping bacterial community structure, but the dispersal of fungi is more limited than that of bacteria. The chapter ends with a discussion about the relationship between community structure and biogeochemical processes. The value of community structure information varies with the process and the degree of metabolic redundancy among the community members for the process.
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35

Gunji, T. Japanese Phrase Structure Grammar: A Unification-based Approach. Springer, 2010.

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36

Gunji, T. Japanese Phrase Structure Grammar: A Unification-Based Approach. Springer London, Limited, 2013.

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37

Taber, Douglass F. Organic Spectroscopic Structure Determination: A Problem-Based Learning Approach. Oxford University Press, USA, 2007.

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38

Lau, M. W. Economic Structure of Trusts: Towards a Property-Based Approach. Oxford University Press, 2011.

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39

Simpson, Jeffrey H. Organic Structure Determination Using 2-D NMR Spectroscopy: A Problem-Based Approach. Elsevier Science & Technology Books, 2011.

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40

Simpson, Jeffrey H. Organic Structure Determination Using 2-D NMR Spectroscopy: A Problem-Based Approach. Elsevier Science & Technology Books, 2010.

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41

Güell, Oriol. A Network-Based Approach to Cell Metabolism: From Structure to Flux Balances. Springer, 2017.

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42

Güell, Oriol. A Network-Based Approach to Cell Metabolism: From Structure to Flux Balances. Springer, 2018.

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43

Crang, Richard, Robert Wise e Sheila Lyons-Sobaski. Plant Anatomy: A Concept-Based Approach to the Structure of Seed Plants. Springer, 2018.

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44

Hilgurt, S. Ya, e O. A. Chemerys. Reconfigurable signature-based information security tools of computer systems. PH “Akademperiodyka”, 2022. http://dx.doi.org/10.15407/akademperiodyka.458.297.

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The book is devoted to the research and development of methods for combining computational structures for reconfigurable signature-based information protection tools for computer systems and networks in order to increase their efficiency. Network security tools based, among others, on such AI-based approaches as deep neural networking, despite the great progress shown in recent years, still suffer from nonzero recognition error probability. Even a low probability of such an error in a critical infrastructure can be disastrous. Therefore, signature-based recognition methods with their theoretically exact matching feature are still relevant when creating information security systems such as network intrusion detection systems, antivirus, anti-spam, and wormcontainment systems. The real time multi-pattern string matching task has been a major performance bottleneck in such systems. To speed up the recognition process, developers use a reconfigurable hardware platform based on FPGA devices. Such platform provides almost software flexibility and near-ASIC performance. The most important component of a signature-based information security system in terms of efficiency is the recognition module, in which the multipattern matching task is directly solved. It must not only check each byte of input data at speeds of tens and hundreds of gigabits/sec against hundreds of thousand or even millions patterns of signature database, but also change its structure every time a new signature appears or the operating conditions of the protected system change. As a result of the analysis of numerous examples of the development of reconfigurable information security systems, three most promising approaches to the construction of hardware circuits of recognition modules were identified, namely, content-addressable memory based on digital comparators, Bloom filter and Aho–Corasick finite automata. A method for fast quantification of components of recognition module and the entire system was proposed. The method makes it possible to exclude resource-intensive procedures for synthesizing digital circuits on FPGAs when building complex reconfigurable information security systems and their components. To improve the efficiency of the systems under study, structural-level combinational methods are proposed, which allow combining into single recognition device several matching schemes built on different approaches and their modifications, in such a way that their advantages are enhanced and disadvantages are eliminated. In order to achieve the maximum efficiency of combining methods, optimization methods are used. The methods of: parallel combining, sequential cascading and vertical junction have been formulated and investigated. The principle of multi-level combining of combining methods is also considered and researched. Algorithms for the implementation of the proposed combining methods have been developed. Software has been created that allows to conduct experiments with the developed methods and tools. Quantitative estimates are obtained for increasing the efficiency of constructing recognition modules as a result of using combination methods. The issue of optimization of reconfigurable devices presented in hardware description languages is considered. A modification of the method of affine transformations, which allows parallelizing such cycles that cannot be optimized by other methods, was presented. In order to facilitate the practical application of the developed methods and tools, a web service using high-performance computer technologies of grid and cloud computing was considered. The proposed methods to increase efficiency of matching procedure can also be used to solve important problems in other fields of science as data mining, analysis of DNA molecules, etc. Keywords: information security, signature, multi-pattern matching, FPGA, structural combining, efficiency, optimization, hardware description language.
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45

Miano, Daniele. Introduction. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198786566.003.0001.

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In the Introduction there is a discussion of methodologies for the study of ancient deities. In the monograph as a whole a conceptual approach to the goddess Fortuna will be proposed, which partially uses methods of conceptual history and aims at exploring the connection between deities and concepts. The Introduction discusses the advantages and disadvantages of current approaches to ancient deities and ancient religion (structuralism in particular), and explains the rationale for a study based on concepts and conceptual history, as well as the foreseeable benefits and limitations of this approach. This section also outlines the structure of the book.
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46

Northoff, Georg. How Does the Brain’s Spontaneous Activity Generate Our Thoughts? A cura di Kalina Christoff e Kieran C. R. Fox. Oxford University Press, 2018. http://dx.doi.org/10.1093/oxfordhb/9780190464745.013.9.

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Recent investigations have demonstrated the psychological features (e.g. cognitive, affective, and social) of task-unrelated thoughts, as well as their underlying neural correlates in spontaneous activity, which cover various networks and regions, including the default-mode and central executive networks. Despite impressive progress in recent research, the mechanisms by means of which the brain’s spontaneous activity generates and constitutes thoughts remain unclear. This chapter suggests that the spatiotemporal structure of the brain’s spontaneous activity can integrate both content- and process-based approaches to task-unrelated or spontaneous thought—this amounts to what is described as the “spatiotemporal theory of task-unrelated thought” (STTT). Based on various lines of empirical evidence, the STTT postulates two main spatiotemporal mechanisms, spatiotemporal integration and extension. The STTT provides a novel brain-based spatiotemporal theory of task-unrelated thought that focuses on the brain’s spontaneous activity, including its spatiotemporal structure, which allows integrating content- and process-based approaches.
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47

Brunel, Jean L. P. Goals-Based Wealth Management: An Integrated and Practical Approach to Changing the Structure of Wealth Advisory Practices. Wiley & Sons, Limited, John, 2015.

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48

Brunel, Jean L. P. Goals-Based Wealth Management: An Integrated and Practical Approach to Changing the Structure of Wealth Advisory Practices. Wiley & Sons, Incorporated, John, 2015.

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49

Brunel, Jean L. P. Goals-Based Wealth Management: An Integrated and Practical Approach to Changing the Structure of Wealth Advisory Practices. Wiley & Sons, Incorporated, John, 2015.

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50

Brunel, Jean L. P. Goals-Based Wealth Management: An Integrated and Practical Approach to Changing the Structure of Wealth Advisory Practices. Wiley & Sons, Incorporated, John, 2015.

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